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Neal Young

Research Profile

Disorders

Anatomy

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Parvovirus B19, Human

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TOP 3
Yong-Gang Yao; Xingmin Feng; Sachiko Kajigaya; J Philip McCoy; Leigh Samsel; Giuseppe Torelli; Neal S Young
Accumulation of mtDNA variations in human single CD34(+) cells from maternally related individuals: Effects of aging and family genetic background.
Anna M Aalbers; Andre Baruchel; Rodrigo T Calado; Valerie de Haas; Karin Geleijns; Sachiko Kajigaya; Gertjan J L Kaspers; Taco W Kuijpers; Rob Pieters; Dirk Reinhardt; Jan Trka; Vincent H J van der Velden; Neal S Young; C Michel Zwaan; Marry M van den Heuvel-Eibrink
Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia.
Keyvan Keyvanfar; Prashanth Swamy; Jason Weed; Rodrigo T Calado; Sachiko Kajigaya; Neal S Young
Interphase Chromosome Flow-FISH.

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All Publications

2013: Yong-Gang Yao; Xingmin Feng; Sachiko Kajigaya; J Philip McCoy; Leigh Samsel; Giuseppe Torelli; Neal S Young
Accumulation of mtDNA variations in human single CD34(+) cells from maternally related individuals: Effects of aging and family genetic background.
Stem cell research 2013;10(3):361-70.
2013: Anna M Aalbers; Andre Baruchel; Rodrigo T Calado; Valerie de Haas; Karin Geleijns; Sachiko Kajigaya; Gertjan J L Kaspers; Taco W Kuijpers; Rob Pieters; Dirk Reinhardt; Jan Trka; Vincent H J van der Velden; Neal S Young; C Michel Zwaan; Marry M van den Heuvel-Eibrink
Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia.
British journal of haematology 2013;160(4):559-61.
2012: Keyvan Keyvanfar; Prashanth Swamy; Jason Weed; Rodrigo T Calado; Sachiko Kajigaya; Neal S Young
Interphase Chromosome Flow-FISH.
Blood 2012;120(15):e54-9.
2012: Phillip Scheinberg; Neal S Young
How I treat acquired aplastic anemia.
Blood 2012;120(6):1185-96.
2012: Matthew J Olnes; Loretta Pfannes; Phillip Scheinberg; Aarthie Shenoy; Jerome Groopman; Minjung Kwak; Kelsey Loeliger; Manoj Maniar; Irina Maric; Xin Tian; Zachary Tucker; Barbara Weinstein; Francois Wilhelm; Agnes S M Yong; Neal S Young; Elaine M Sloand
Directed therapy for patients with myelodysplastic syndromes (MDS) by suppression of cyclin D1 with ON 01910.Na.
Leukemia research 2012;36(8):982-9.
2012: Bogdan Dumitriu; Neal S Young
Damage control and its costs: BM failure in Fanconi anemia stems from overactive p53/p21.
Cell stem cell 2012;11(1):7-8.
2012: Matthew J Olnes; Ankur R Parikh; Phillip Scheinberg; Susan Soto; Yong Tang; Colin O Wu; Neal S Young; Angelique Biancotto; Katherine R Calvo; Ronan Desmond; Bogdan Dumitriu; Xingmin Feng; Jay Lozier; Cynthia E Dunbar
Eltrombopag and improved hematopoiesis in refractory aplastic anemia.
The New England journal of medicine 2012;367(1):11-9.
2012: Neal S Young
Bone marrow failure and the new telomere diseases: practice and research.
Hematology (Amsterdam, Netherlands) 2012;17 Suppl 1():S18-21.
2012: Rodrigo T Calado; J N Cooper; H M Padilla-Nash; T Ried; P Scheinberg; Elaine M Sloand; C O Wu; Neal S Young
Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia.
Leukemia 2012;26(4):700-7.
2012: Anna M Aalbers; Rodrigo T Calado; Sachiko Kajigaya; Marry M van den Heuvel-Eibrink; Vincent H J van der Velden; Neal S Young
Human telomere disease due to disruption of the CCAAT box of the TERC promoter.
Blood 2012;119(13):3060-3.
2012: Matthew J Olnes; Hesed Padilla-Nash; Loretta Pfannes; Andrea Poon; Thomas Ried; Susan F Leitman; Kelsey Loeliger; Susan J Miranda; Zachary Tucker; Yu Ying Yau; Neal S Young; Elaine M Sloand
Effects of granulocyte-colony-stimulating factor on Monosomy 7 aneuploidy in healthy hematopoietic stem cell and granulocyte donors.
Transfusion 2012;52(3):537-41.
2011: Phillip Scheinberg; Priscila Scheinberg; Barbara Weinstein; Colin O Wu; Angélique Biancotto; Olga Nunez; Neal S Young
Horse versus rabbit antithymocyte globulin in acquired aplastic anemia.
The New England journal of medicine 2011;365(5):430-8.
2011: Andrew J Erie; Keyvan Keyvanfar; J Philip McCoy; Leigh Samsel; Tomoiku Takaku; Neal S Young; Marie J Desierto; Jichun Chen
MHC class II upregulation and colocalization with Fas in experimental models of immune-mediated bone marrow failure.
Experimental hematology 2011;39(8):837-49.
2011: Rodrigo T Calado; Jennifer Brudno; Paulomi Mehta; Joseph J Kovacs; Colin Wu; Marco Zago; STEPHEN CHANOCK; Thomas D Boyer; Neal S Young
Constitutional telomerase mutations are genetic risk factors for cirrhosis.
Hepatology (Baltimore, Md.) 2011;53(5):1600-7.
2011: Xingmin Feng; Phillip Scheinberg; Colin O Wu; Leigh Samsel; Olga Nunez; Courtney Prince; Rebecca D Ganetzky; J Philip McCoy; Jaroslaw P Maciejewski; Neal S Young
Cytokine signature profiles in acquired aplastic anemia and myelodysplastic syndromes.
Haematologica 2011;96(4):602-6.
2011: Elaine M Sloand; J Joseph Melenhorst; Zachary C G Tucker; Loretta Pfannes; Jason M Brenchley; Agnes S M Yong; Valeria Visconte; Colin Wu; Emma Gostick; Phillip Scheinberg; Matthew J Olnes; Daniel C Douek; David A Price; A John Barrett; Neal S Young
T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy.
Blood 2011;117(9):2691-9.
2010: Elaine M Sloand; Matthew J Olnes; Aarthie Shenoy; Barbara Weinstein; Carol Boss; Kelsey Loeliger; Colin O Wu; Kenneth More; A John Barrett; Phillip Scheinberg; Neal S Young
Alemtuzumab treatment of intermediate-1 myelodysplasia patients is associated with sustained improvement in blood counts and cytogenetic remissions.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(35):5166-73.
2010: Regis Peffault de Latour; Valeria Visconte; Tomoiku Takaku; Colin Wu; Andrew J Erie; Annahita K Sarcon; Marie J Desierto; Phillip Scheinberg; Keyvan Keyvanfar; Olga Nunez; Jichun Chen; Neal S Young
Th17 immune responses contribute to the pathophysiology of aplastic anemia.
Blood 2010;116(20):4175-84.
2010: Susan Wong; Keyvan Keyvanfar; Zhihong Wan; Sachiko Kajigaya; Neal S Young; Ning Zhi
Establishment of an erythroid cell line from primary CD36+ erythroid progenitor cells.
Experimental hematology 2010;38(11):994-1005.e1-2.
2010: Phillip Scheinberg; James N Cooper; Elaine M Sloand; Colin O Wu; Rodrigo T Calado; Neal S Young
Association of telomere length of peripheral blood leukocytes with hematopoietic relapse, malignant transformation, and survival in severe aplastic anemia.
JAMA : the journal of the American Medical Association 2010;304(12):1358-64.
2010: Phillip Scheinberg; Michael Marte; Olga Nunez; Neal S Young
Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine.
Haematologica 2010;95(7):1075-80.
2010: Valeria Visconte; Nalini Raghavachari; Delong Liu; Keyvan Keyvanfar; Marie J Desierto; Jichun Chen; Neal S Young
Phenotypic and functional characterization of a mouse model of targeted Pig-a deletion in hematopoietic cells.
Haematologica 2010;95(2):214-23.
2010: Yong Tang; Marie J Desierto; Jichun Chen; Neal S Young
The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failure.
Blood 2010;115(3):541-8.
2010: Neal S Young
Telomere biology and telomere diseases: implications for practice and research.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2010;2010():30-5.
2010: Neal S Young; Andrea Bacigalupo; Judith C W Marsh
Aplastic anemia: pathophysiology and treatment.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(1 Suppl):S119-25.
2009: Rodrigo T Calado; Neal S Young
Telomere diseases.
The New England journal of medicine 2009;361(24):2353-65.
2009: Rodrigo T Calado; J A Regal; Sachiko Kajigaya; Neal S Young
Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations.
European journal of clinical investigation 2009;39(11):1025-32.
2009: Rodrigo T Calado; William T Yewdell; Keisha L Wilkerson; Joshua A Regal; Sachiko Kajigaya; Constantine Straturis; Neal S Young
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Blood 2009;114(11):2236-43.
2009: Sharon A Savage; Inderjeet Dokal; Mary Armanios; Geraldine Aubert; Edward W Cowen; Demetrio L Domingo; Neelam Giri; Mark H Greene; Paul J Orchard; Jakub Tolar; Ekaterini Tsilou; Carter Van Waes; Judy M Y Wong; Neal S Young; BLANCHE ALTER
Dyskeratosis congenita: the first NIH clinical research workshop.
Pediatric blood & cancer 2009;53(3):520-3.
2009: Jessica M Valdez; Phillip Scheinberg; Neal S Young; THOMAS WALSH
Infections in patients with aplastic anemia.
Seminars in hematology 2009;46(3):269-76.
2009: Tomoiku Takaku; Rodrigo T Calado; Sachiko Kajigaya; Neal S Young
Interleukin-23 receptor (IL-23R) gene polymorphisms in acquired aplastic anemia.
Annals of hematology 2009;88(7):653-7.
2009: Annahita K Sarcon; Marie J Desierto; Wenjun Zhou; Valeria Visconte; Federica Gibellini; Jichun Chen; Neal S Young
Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure.
Experimental hematology 2009;37(4):477-86.
2009: Stephanie O Omokaro; Marie J Desierto; Michael Eckhaus; Felicia M Ellison; Jichun Chen; Neal S Young
Lymphocytes with aberrant expression of Fas or Fas ligand attenuate immune bone marrow failure in a mouse model.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3414-22.
2009: Phillip Scheinberg; Colin O Wu; Olga Nunez; Priscila Scheinberg; Carol Boss; Elaine M Sloand; Neal S Young
Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study.
Haematologica 2009;94(3):348-54.
2009: Yong Tang; Jichun Chen; Neal S Young
Expansion of haematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4.
British journal of haematology 2009;144(4):603-12.
2009: Rodrigo T Calado; Joshua A Regal; Mark Hills; William T Yewdell; Leandro F Dalmazzo; Marco Zago; Peter M Lansdorp; Donna Hogge; STEPHEN CHANOCK; Elihu H Estey; Roberto P Falcão; Neal S Young
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1187-92.
2009: Rodrigo T Calado; Joshua A Regal; David E Kleiner; David S Schrump; Nathan R Peterson; Veronica Pons; STEPHEN CHANOCK; Peter M Lansdorp; Neal S Young
A spectrum of severe familial liver disorders associate with telomerase mutations.
PloS one 2009;4(11):e7926.
2009: Neal S Young
Paroxysmal nocturnal hemoglobinuria and myelodysplastic syndromes: clonal expansion of PIG-A-mutant hematopoietic cells in bone marrow failure.
Haematologica 2009;94(1):3-7.
2009: Phillip Scheinberg; Colin O Wu; Olga Nunez; Neal S Young
Predicting response to immunosuppressive therapy and survival in severe aplastic anaemia.
British journal of haematology 2009;144(2):206-16.
2008: Elaine M Sloand; Loretta Pfannes; Phillip Scheinberg; Kenneth More; Colin O Wu; McDonald Horne; Neal S Young
Increased soluble urokinase plasminogen activator receptor (suPAR) is associated with thrombosis and inhibition of plasmin generation in paroxysmal nocturnal hemoglobinuria (PNH) patients.
Experimental hematology 2008;36(12):1616-24.
2008: Phillip Scheinberg; Colin O Wu; Olga Nunez; Neal S Young
Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine.
The Journal of pediatrics 2008;153(6):814-9.
2008: Jichun Chen; Felicia M Ellison; Keyvan Keyvanfar; Stephanie O Omokaro; Marie J Desierto; Michael A Eckhaus; Neal S Young
Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice.
Experimental hematology 2008;36(10):1236-43.
2008: Jörg Schubert; Peter Hillmen; Alexander Röth; Neal S Young; Modupe Elebute; Jeff Szer; Giacomo Gianfaldoni; Gérard Socié; Paul Browne; Robert Geller; Russell P Rother; Petra Muus
Eculizumab, a terminal complement inhibitor, improves anaemia in patients with paroxysmal nocturnal haemoglobinuria.
British journal of haematology 2008;142(2):263-72.
2008: Claudia Filippone; Ning Zhi; Susan Wong; Jun Lu; Sachiko Kajigaya; Giorgio Gallinella; Laura Kakkola; Maria Söderlund-Venermo; Neal S Young; Kevin E Brown
VP1u phospholipase activity is critical for infectivity of full-length parvovirus B19 genomic clones.
Virology 2008;374(2):444-52.
2008: Neal S Young; Phillip Scheinberg; Rodrigo T Calado
Aplastic anemia.
Current opinion in hematology 2008;15(3):162-8.
2008: Rodrigo T Calado; Neal S Young
Telomere maintenance and human bone marrow failure.
Blood 2008;111(9):4446-55.
2008: Neal S Young; David W Kaufman
The epidemiology of acquired aplastic anemia.
Haematologica 2008;93(4):489-92.
2008: Xingmin Feng; Sachiko Kajigaya; Elena E Solomou; Keyvan Keyvanfar; Xiuli Xu; Nalini Raghavachari; Peter J Munson; Thomas M Herndon; Jichun Chen; Neal S Young
Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro.
Blood 2008;111(7):3675-83.
2008: Susan Wong; Ning Zhi; Claudia Filippone; Keyvan Keyvanfar; Sachiko Kajigaya; Kevin E Brown; Neal S Young
Ex vivo-generated CD36+ erythroid progenitors are highly permissive to human parvovirus B19 replication.
Journal of virology 2008;82(5):2470-6.
2008: Robert A Brodsky; Neal S Young; Elisabetta Antonioli; Antonio M Risitano; Hubert Schrezenmeier; Jörg Schubert; Anna Gaya; Luke Coyle; Carlos de Castro; Chieh-Lin Fu; Jaroslaw P Maciejewski; Monica Bessler; Henk-André Kroon; Russell P Rother; Peter Hillmen
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.
Blood 2008;111(4):1840-7.
2007: Georgios Amexis; Neal S Young
Multiple antigenic peptides as vaccine platform for the induction of humoral responses against dengue-2 virus.
Viral immunology 2007;20(4):657-63.
2007: Peter Hillmen; Petra Muus; Ulrich Dührsen; Antonio M Risitano; Jörg Schubert; Lucio Luzzatto; Hubert Schrezenmeier; Jeff Szer; Robert A Brodsky; Anita Hill; Gérard Socié; Monica Bessler; Scott A Rollins; Leonard Bell; Russell P Rother; Neal S Young
Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.
Blood 2007;110(12):4123-8.
2007: Gabriela M Baerlocher; Elaine M Sloand; Neal S Young; Peter M Lansdorp
Telomere length in paroxysmal nocturnal hemoglobinuria correlates with clone size.
Experimental hematology 2007;35(12):1777-81.
2007: Yong-Gang Yao; Richard W Childs; Sachiko Kajigaya; J Philip McCoy; Neal S Young
Mitochondrial DNA sequence heterogeneity of single CD34+ cells after nonmyeloablative allogeneic stem cell transplantation.
Stem cells (Dayton, Ohio) 2007;25(10):2670-6.
2007: Elena E Solomou; Katayoun Rezvani; Stephan Mielke; Daniela Malide; Keyvan Keyvanfar; Valeria Visconte; Sachiko Kajigaya; A John Barrett; Neal S Young
Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia.
Blood 2007;110(5):1603-6.
2007: Rodrigo T Calado; Solomon A Graf; Keisha L Wilkerson; Sachiko Kajigaya; Phil J Ancliff; Yigal Dror; STEPHEN CHANOCK; Peter M Lansdorp; Neal S Young
Mutations in the SBDS gene in acquired aplastic anemia.
Blood 2007;110(4):1141-6.
2007: Vinod Gidvani; Shakti H Ramkissoon; Elaine M Sloand; Neal S Young
Cytokine gene polymorphisms in acquired bone marrow failure.
American journal of hematology 2007;82(8):721-4.
2007: Elaine M Sloand; Elizabeth J Read; Phillip Scheinberg; Yong Tang; Kenneth More; Susan F Leitman; Jaroslaw Maciejewski; Neal S Young
Mobilization, collection, and immunomagnetic selection of peripheral blood CD34 cells in recovered aplastic anemia patients.
Transfusion 2007;47(7):1250-3.
2007: Elena E Solomou; Susan Wong; Valeria Visconte; Federica Gibellini; Neal S Young
Decreased TCR zeta-chain expression in T cells from patients with acquired aplastic anaemia.
British journal of haematology 2007;138(1):72-6.
2007: Elena E Solomou; Federica Gibellini; Brian Stewart; Daniela Malide; Maria Berg; Valeria Visconte; Spencer Green; Richard Childs; STEPHEN CHANOCK; Neal S Young
Perforin gene mutations in patients with acquired aplastic anemia.
Blood 2007;109(12):5234-7.
2007: Solomon A Graf; Rodrigo T Calado; Sachiko Kajigaya; Neal S Young
RMRP mutations in hematological disorders.
Clinical genetics 2007;71(5):468-70.
2007: Phillip Scheinberg; Steven H Fischer; Li Li; Olga Nunez; Colin O Wu; Elaine M Sloand; Jeffrey I Cohen; Neal S Young; A John Barrett
Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia.
Blood 2007;109(8):3219-24.
2007: Jichun Chen; Felicia M Ellison; Michael Eckhaus; Aleah L Smith; Keyvan Keyvanfar; Rodrigo T Calado; Neal S Young
Minor antigen h60-mediated aplastic anemia is ameliorated by immunosuppression and the infusion of regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4159-68.
2007: Solomon A Graf; Rodrigo T Calado; Neal S Young
PTPN22 620W allele is not associated with aplastic anemia.
American journal of hematology 2007;82(4):291-2.
2007: Elaine M Sloand; Loretta Pfannes; Gubin Chen; Simant Shah; Elena E Solomou; John Barrett; Neal S Young
CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins.
Blood 2007;109(6):2399-405.
2007: Yong-Gang Yao; Felicia M Ellison; J Philip McCoy; Jichun Chen; Neal S Young
Age-dependent accumulation of mtDNA mutations in murine hematopoietic stem cells is modulated by the nuclear genetic background.
Human molecular genetics 2007;16(3):286-94.
2007: Zhong-Tao Xin; Adam D Beauchamp; Rodrigo T Calado; Jennifer W Bradford; Joshua A Regal; Aarthi Shenoy; Yuying Liang; Peter M Lansdorp; Neal S Young; Hinh Ly
Functional characterization of natural telomerase mutations found in patients with hematologic disorders.
Blood 2007;109(2):524-32.
2007: Yong-Gang Yao; Yoji Ogasawara; Sachiko Kajigaya; Jeffrey J Molldrem; Roberto P Falcão; Maria-Carolina Pintão; J Philip McCoy; Edgar G Rizzatti; Neal S Young
Mitochondrial DNA sequence variation in single cells from leukemia patients.
Blood 2007;109(2):756-62.
2007: Yong-Gang Yao; Hans-Jürgen Bandelt; Neal S Young
External contamination in single cell mtDNA analysis.
PloS one 2007;2(8):e681.
2006: Neal S Young
Hematologic manifestations and diagnosis of parvovirus B19 infections.
Clinical advances in hematology & oncology : H&O 2006;4(12):908-10.
2006: Neal S Young; Rodrigo T Calado; Phillip Scheinberg
Current concepts in the pathophysiology and treatment of aplastic anemia.
Blood 2006;108(8):2509-19.
2006: Elaine M Sloand; Agnes S M Yong; Shakti H Ramkissoon; Elena E Solomou; Tullia C Bruno; Sonnie Kim; Monika Fuhrer; Sachiko Kajigaya; A John Barrett; Neal S Young
Granulocyte colony-stimulating factor preferentially stimulates proliferation of monosomy 7 cells bearing the isoform IV receptor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(39):14483-8.
2006: Peter Hillmen; Neal S Young; Jörg Schubert; Robert A Brodsky; Gérard Socié; Petra Muus; Alexander Röth; Jeff Szer; Modupe Elebute; Ryotaro Nakamura; Paul Browne; Antonio M Risitano; Anita Hill; Hubert Schrezenmeier; Chieh-Lin Fu; Jaroslaw Maciejewski; Scott A Rollins; Christopher F Mojcik; Russell P Rother; Lucio Luzzatto
The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.
The New England journal of medicine 2006;355(12):1233-43.
2006: Georgios Amexis; Neal S Young
Parvovirus B19 empty capsids as antigen carriers for presentation of antigenic determinants of dengue 2 virus.
The Journal of infectious diseases 2006;194(6):790-4.
2006: Phillip Scheinberg; Olga Nunez; Neal S Young
Retreatment with rabbit anti-thymocyte globulin and ciclosporin for patients with relapsed or refractory severe aplastic anaemia.
British journal of haematology 2006;133(6):622-7.
2006: Phillip Scheinberg; Olga Nunez; Colin Wu; Neal S Young
Treatment of severe aplastic anaemia with combined immunosuppression: anti-thymocyte globulin, ciclosporin and mycophenolate mofetil.
British journal of haematology 2006;133(6):606-11.
2006: Elena E Solomou; Keyvan Keyvanfar; Neal S Young
T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia.
Blood 2006;107(10):3983-91.
2006: Yoji Ogasawara; Georgios Amexis; Hiroki Yamaguchi; Sachiko Kajigaya; Stephen H Leppla; Neal S Young
Recombinant viral-like particles of parvovirus B19 as antigen carriers of anthrax protective antigen.
In vivo (Athens, Greece) 2006;20(3):319-24.
2006: Sharon A Savage; Rodrigo T Calado; Zhong-Tao Xin; Hinh Ly; Neal S Young; STEPHEN CHANOCK
Genetic variation in telomeric repeat binding factors 1 and 2 in aplastic anemia.
Experimental hematology 2006;34(5):664-71.
2006: Ramaprasad Srinivasan; Yoshiyuki Takahashi; J Philip McCoy; Igor Espinoza-Delgado; Colleen Dorrance; Takehito Igarashi; Andreas Lundqvist; A John Barrett; Neal S Young; Nancy Geller; Richard W Childs
Overcoming graft rejection in heavily transfused and allo-immunised patients with bone marrow failure syndromes using fludarabine-based haematopoietic cell transplantation.
British journal of haematology 2006;133(3):305-14.
2006: Shakti H Ramkissoon; Lori Mainwaring; Yoji Ogasawara; Keyvan Keyvanfar; J Philip McCoy; Elaine M Sloand; Sachiko Kajigaya; Neal S Young
Hematopoietic-specific microRNA expression in human cells.
Leukemia research 2006;30(5):643-7.
2006: Elaine M Sloand; Phillip Scheinberg; Jaroslaw Maciejewski; Neal S Young
Brief communication: Successful treatment of pure red-cell aplasia with an anti-interleukin-2 receptor antibody (daclizumab).
Annals of internal medicine 2006;144(3):181-5.
2006: Shakti H Ramkissoon; Lori Mainwaring; Elaine M Sloand; Neal S Young; Sachiko Kajigaya
Nonisotopic detection of microRNA using digoxigenin labeled RNA probes.
Molecular and cellular probes 2006;20(1):1-4.
2006: Neal S Young
Pathophysiologic mechanisms in acquired aplastic anemia.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2006;():72-7.
2006: Weihua Zeng; Akira Miyazato; Guibin Chen; Sachiko Kajigaya; Neal S Young; Jaroslaw P Maciejewski
Interferon-gamma-induced gene expression in CD34 cells: identification of pathologic cytokine-specific signature profiles.
Blood 2006;107(1):167-75.
2005: Yoji Ogasawara; Kazutaka Nakayama; Magdalena Tarnowka; J Philip McCoy; Sachiko Kajigaya; Barbara C Levin; Neal S Young
Mitochondrial DNA spectra of single human CD34+ cells, T cells, B cells, and granulocytes.
Blood 2005;106(9):3271-84.
2005: Jichun Chen; Justin S Brandt; Felicia M Ellison; Rodrigo T Calado; Neal S Young
Defective stromal cell function in a mouse model of infusion-induced bone marrow failure.
Experimental hematology 2005;33(8):901-8.
2005: Elaine M Sloand; Lori Mainwaring; Monika Fuhrer; Shakti H Ramkissoon; Antonio M Risitano; Keyvan Keyvanafar; Jun Lu; Atanu Basu; A John Barrett; Neal S Young
Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome.
Blood 2005;106(3):841-51.
2005: Guibin Chen; Weihua Zeng; Jaroslaw P Maciejewski; K Kcyvanfar; Eric M Billings; Neal S Young
Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in 'normal' phenotype cells.
Leukemia 2005;19(5):862-8.
2005: Hiroki Yamaguchi; Rodrigo T Calado; Hinh Ly; Sachiko Kajigaya; Gabriela M Baerlocher; STEPHEN CHANOCK; Peter M Lansdorp; Neal S Young
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia.
The New England journal of medicine 2005;352(14):1413-24.
2005: Hinh Ly; Rodrigo T Calado; Paulette Allard; Gabriela M Baerlocher; Peter M Lansdorp; Neal S Young; Tristam PARSLOW
Functional characterization of telomerase RNA variants found in patients with hematologic disorders.
Blood 2005;105(6):2332-9.
2005: Neal S Young
Paroxysmal nocturnal hemoglobinuria: current issues in pathophysiology and treatment.
Current hematology reports 2005;4(2):103-9.
2005: Antonio M Risitano; Jaroslaw P Maciejewski; Pawel Muranski; Marcin W Wlodarski; Christine L O'Keefe; Elaine M Sloand; Neal S Young
Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients.
Leukemia 2005;19(2):217-22.
2004: Guibin Chen; Weihua Zeng; Akira Miyazato; Eric M Billings; Jaroslaw P Maciejewski; Sachiko Kajigaya; Elaine M Sloand; Neal S Young
Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities.
Blood 2004;104(13):4210-8.
2004: Michael L Bloom; Adam G Wolk; Karen L Simon-Stoos; Julie S Bard; Jichun Chen; Neal S Young
A mouse model of lymphocyte infusion-induced bone marrow failure.
Experimental hematology 2004;32(12):1163-72.
2004: Elaine M Sloand; Lori Mainwaring; Keyvan Keyvanfar; Jichun Chen; Jaroslaw Maciejewski; HARVEY KLEIN; Neal S Young
Transfer of glycosylphosphatidylinositol-anchored proteins to deficient cells after erythrocyte transfusion in paroxysmal nocturnal hemoglobinuria.
Blood 2004;104(12):3782-8.
2004: Jichun Chen; Karen Lipovsky; Felicia M Ellison; Rodrigo T Calado; Neal S Young
Bystander destruction of hematopoietic progenitor and stem cells in a mouse model of infusion-induced bone marrow failure.
Blood 2004;104(6):1671-8.
2004: Weihua Zeng; Sachiko Kajigaya; Guibin Chen; Antonio M Risitano; Olga Nunez; Neal S Young
Transcript profile of CD4+ and CD8+ T cells from the bone marrow of acquired aplastic anemia patients.
Experimental hematology 2004;32(9):806-14.
2004: William G Kearns; Hiroki Yamaguchi; Neal S Young; Johnson Ming-Yu Liu
Centrosome amplification and aneuploidy in bone marrow failure patients.
Genes, chromosomes & cancer 2004;40(4):329-33.
2004: Antonio M Risitano; Jaroslaw P Maciejewski; Spencer Green; Magdalena Plasilova; Weihua Zeng; Neal S Young
In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing.
Lancet 2004;364(9431):355-64.
2004: William G Kearns; Joanne F Sutton; Jaroslaw P Maciejewski; Neal S Young; Johnson Ming-Yu Liu
Genomic instability in bone marrow failure syndromes.
American journal of hematology 2004;76(3):220-4.
2004: Myung Geun Shin; Sachiko Kajigaya; Magdalena Tarnowka; J Philip McCoy; Barbara C Levin; Neal S Young
Mitochondrial DNA sequence heterogeneity in circulating normal human CD34 cells and granulocytes.
Blood 2004;103(12):4466-77.
2004: Jun Lu; Atanu Basu; J Joseph Melenhorst; Neal S Young; Kevin E Brown
Analysis of T-cell repertoire in hepatitis-associated aplastic anemia.
Blood 2004;103(12):4588-93.
2004: Jan Simak; Karel Holada; Antonio M Risitano; Jan Zivny; Neal S Young; Jaroslav G Vostal
Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria.
British journal of haematology 2004;125(6):804-13.
2004: Guibin Chen; Weihua Zeng; Spencer Green; Neal S Young
Frequent HPRT mutations in paroxysmal nocturnal haemoglobinuria reflect T cell clonal expansion, not genomic instability.
British journal of haematology 2004;125(3):383-91.
2004: Magdalena Plasilova; Antonio M Risitano; Christine L O'Keefe; Alexander Rodriguez; Marcin W Wlodarski; Neal S Young; Jaroslaw Maciejewski
Shared and individual specificities of immunodominant cytotoxic T-cell clones in paroxysmal nocturnal hemoglobinuria as determined by molecular analysis.
Experimental hematology 2004;32(3):261-9.
2004: Yoshiyuki Takahashi; J Philip McCoy; Cristian Carvallo; Candido Rivera; Takehito Igarashi; Ramaprasad Srinivasan; Neal S Young; Richard W Childs
In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation.
Blood 2004;103(4):1383-90.
2004: Neal S Young; Kevin E Brown
Parvovirus B19.
The New England journal of medicine 2004;350(6):586-97.
2004: Joanne F Sutton; Martin Stacey; William G Kearns; Thomas S Rieg; Neal S Young; Johnson Ming-Yu Liu
Increased risk for aplastic anemia and myelodysplastic syndrome in individuals lacking glutathione S-transferase genes.
Pediatric blood & cancer 2004;42(2):122-6.
2004: Christine L O'Keefe; Magdalena Plasilova; Marcin W Wlodarski; Antonio M Risitano; Alexander R Rodriguez; Evan C Howe; Neal S Young; Eric D Hsi; Jaroslaw P Maciejewski
Molecular analysis of TCR clonotypes in LGL: a clonal model for polyclonal responses.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1960-9.
2004: Myung Geun Shin; Sachiko Kajigaya; J Philip McCoy; Barbara C Levin; Neal S Young
Marked mitochondrial DNA sequence heterogeneity in single CD34+ cell clones from normal adult bone marrow.
Blood 2004;103(2):553-61.
2004: Guibin Chen; Hoon Kook; Weihua Zeng; Neal S Young; Jaroslaw P Maciejewski
Is there a direct effect of antithymocyte globulin on hematopoiesis?
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(3):255-61.
2004: Weihua Zeng; Guibin Chen; Sachiko Kajigaya; Olga Nunez; Alexandra Charrow; Eric M Billings; Neal S Young
Gene expression profiling in CD34 cells to identify differences between aplastic anemia patients and healthy volunteers.
Blood 2004;103(1):325-32.
2003: Patrick F Fogarty; Hiroki Yamaguchi; Adrian Wiestner; Gabriela M Baerlocher; Elaine M Sloand; Weihua S Zeng; Elizabeth J Read; Peter M Lansdorp; Neal S Young
Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA.
Lancet 2003;362(9396):1628-30.
2003: Takeji Umemura; Eiji Tanaka; George Ostapowicz; Kevin E Brown; Stefan Heringlake; Nicolaos C Tassopoulos; Richard Y-H Wang; Anthony E T Yeo; James Shih; Koji Orii; Neal S Young; Angelos Hatzakis; Michael P Manns; William M Lee; Kendo Kiyosawa; Harvey Alter
Investigation of SEN virus infection in patients with cryptogenic acute liver failure, hepatitis-associated aplastic anemia, or acute and chronic non-A-E hepatitis.
The Journal of infectious diseases 2003;188(10):1545-52.
2003: Jaroslaw P Maciejewski; Elaine M Sloand; Olga Nunez; Carol Boss; Neal S Young
Recombinant humanized anti-IL-2 receptor antibody (daclizumab) produces responses in patients with moderate aplastic anemia.
Blood 2003;102(10):3584-6.
2003: Minoo Battiwalla; J Joseph Melenhorst; Yogen Saunthararajah; Ryotaro Nakamura; Jeffrey J Molldrem; Neal S Young; A John Barrett
HLA-DR4 predicts haematological response to cyclosporine in T-large granular lymphocyte lymphoproliferative disorders.
British journal of haematology 2003;123(3):449-53.
2003: Elaine M Sloand; Richard W Childs; Scott Solomon; Adeira Greene; Neal S Young; A John Barrett
The graft-versus-leukemia effect of nonmyeloablative stem cell allografts may not be sufficient to cure chronic myelogenous leukemia.
Bone marrow transplantation 2003;32(9):897-901.
2003: Elaine M Sloand; Monika Fuhrer; Keyvan Keyvanfar; Lori Mainwaring; Jaroslaw Maciejewski; Yu Wang; Sarah Johnson; A John Barrett; Neal S Young
Cytogenetic abnormalities in paroxysmal nocturnal haemoglobinuria usually occur in haematopoietic cells that are glycosylphosphatidylinositol-anchored protein (GPI-AP) positive.
British journal of haematology 2003;123(1):173-6.
2003: Hiroki Yamaguchi; Gabriela M Baerlocher; Peter M Lansdorp; STEPHEN CHANOCK; Olga Nunez; Elaine M Sloand; Neal S Young
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome.
Blood 2003;102(3):916-8.
2003: Susan Wong; Neal S Young; Kevin E Brown
Prevalence of parvovirus B19 in liver tissue: no association with fulminant hepatitis or hepatitis-associated aplastic anemia.
The Journal of infectious diseases 2003;187(10):1581-6.
2003: Hiroki Yamaguchi; Laura Aridgides; Weihua Zeng; Christopher J Osgood; Neal S Young; Johnson Ming-Yu Liu
Genetic and transcriptional analysis of spindle checkpoint genes in bone marrow failure patients.
Blood cells, molecules & diseases 2003;30(3):307-11.
2003: Scott R Solomon; Ryotaro Nakamura; Elizabeth J Read; Susan F Leitman; Charles Carter; Richard Childs; Cynthia E Dunbar; Neal S Young; A John Barrett
Cyclosporine is required to prevent severe acute GVHD following T-cell-depleted peripheral blood stem cell transplantation.
Bone marrow transplantation 2003;31(9):783-8.
2003: Myung Geun Shin; Sachiko Kajigaya; Barbara C Levin; Neal S Young
Mitochondrial DNA mutations in patients with myelodysplastic syndromes.
Blood 2003;101(8):3118-25.
2003: Stephen Rosenfeld; dean follmann; Olga Nunez; Neal S Young
Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome.
JAMA : the journal of the American Medical Association 2003;289(9):1130-5.
2003: Antonio M Risitano; Karel Holada; Guibin Chen; Jan Simak; Jaroslav G Vostal; Neal S Young; Jaroslaw P Maciejewski
CD34+ cells from paroxysmal nocturnal hemoglobinuria (PNH) patients are deficient in surface expression of cellular prion protein (PrPc).
Experimental hematology 2003;31(1):65-72.
2002: Elaine M Sloand; Sonnie Kim; Monika Fuhrer; Antonio M Risitano; Ryotaro Nakamura; Jaroslaw P Maciejewski; A John Barrett; Neal S Young
Fas-mediated apoptosis is important in regulating cell replication and death in trisomy 8 hematopoietic cells but not in cells with other cytogenetic abnormalities.
Blood 2002;100(13):4427-32.
2002: John F Tisdale; Jaroslaw P Maciejewski; Olga Nuñez; Stephen Rosenfeld; Neal S Young
Late complications following treatment for severe aplastic anemia (SAA) with high-dose cyclophosphamide (Cy): follow-up of a randomized trial.
Blood 2002;100(13):4668-70.
2002: Weihua Zeng; Jaroslaw P Maciejewski; Guibin Chen; Antonio M Risitano; Martha Kirby; Sachiko Kajigaya; Neal S Young
Selective reduction of natural killer T cells in the bone marrow of aplastic anaemia.
British journal of haematology 2002;119(3):803-9.
2002: Yogen Saunthararajah; Ryotaro Nakamura; Jun-Mo Nam; Jamie Robyn; Fausto R Loberiza; Jaroslaw P Maciejewski; Toni Simonis; Jeffrey J Molldrem; Neal S Young; A John Barrett
HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome.
Blood 2002;100(5):1570-4.
2002: Elaine M Sloand; Sonnie Kim; Jaroslaw P Maciejewski; John F Tisdale; dean follmann; Neal S Young
Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia.
Blood 2002;100(4):1185-91.
2002: Jeffrey J Molldrem; Eric Leifer; Erkut Bahceci; Yogen Saunthararajah; Mary Rivera; Cynthia Dunbar; Johnson Ming-Yu Liu; Riotoro Nakamura; Neal S Young; A John Barrett
Antithymocyte globulin for treatment of the bone marrow failure associated with myelodysplastic syndromes.
Annals of internal medicine 2002;137(3):156-63.
2002: Neal S Young; Jaroslaw P Maciejewski; Elaine M Sloand; Guiben Chen; Weihua Zeng; Antonio M Risitano; Akira Miyazato
The relationship of aplastic anemia and PNH.
International journal of hematology 2002;76 Suppl 2():168-72.
2002: Jaroslaw P Maciejewski; Antonio M Risitano; Hoon Kook; Weihua Zeng; Guibin Chen; Neal S Young
Immune pathophysiology of aplastic anemia.
International journal of hematology 2002;76 Suppl 1():207-14.
2002: Shoichi Nagakura; Sonoko Ishihara; Daniel E Dunn; Jun-ichi Nishimura; Tatsuya Kawaguchi; Kentaro Horikawa; Michihiro Hidaka; Tadashi Kagimoto; Nozomu Eto; Hiroaki Mitsuya; Taroh Kinoshita; Neal S Young; Hideki Nakakuma
Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro.
Blood 2002;100(3):1031-7.
2002: Guibin Chen; Martha Kirby; Weihua Zeng; Neal S Young; Jaroslaw P Maciejewski
Superior growth of glycophosphatidy linositol-anchored protein-deficient progenitor cells in vitro is due to the higher apoptotic rate of progenitors with normal phenotype in vivo.
Experimental hematology 2002;30(7):774-82.
2002: Karel Holada; Jan Simak; Antonio M Risitano; Jaroslaw Maciejewski; Neal S Young; Jaroslav G Vostal
Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein.
Blood 2002;100(1):341-3.
2002: Antonio M Risitano; Hoon Kook; Weihua Zeng; Guibin Chen; Neal S Young; Jaroslaw P Maciejewski
Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by V beta CDR3 spectratyping and flow cytometry.
Blood 2002;100(1):178-83.
2002: Hoon Kook; Antonio M Risitano; Weihua Zeng; Marcin W Wlodarski; Craig Lottemann; Ryotaro Nakamura; John Barrett; Neal S Young; Jaroslaw P Maciejewski
Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens.
Blood 2002;99(10):3668-75.
2002: Jaroslaw P Maciejewski; Antonio M Risitano; Elaine M Sloand; Olga Nunez; Neal S Young
Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia.
Blood 2002;99(9):3129-35.
2002: Neal S Young
Acquired aplastic anemia.
Annals of internal medicine 2002;136(7):534-46.
2002: Jaroslaw P Maciejewski; Antonio M Risitano; Elaine M Sloand; Laura Wisch; Nancy Geller; John A Barrett; Neal S Young; Antonio M Ristiano
A pilot study of the recombinant soluble human tumour necrosis factor receptor (p75)-Fc fusion protein in patients with myelodysplastic syndrome.
British journal of haematology 2002;117(1):119-26.
2002: Neal S Young
Immunosuppressive treatment of acquired aplastic anemia and immune-mediated bone marrow failure syndromes.
International journal of hematology 2002;75(2):129-40.
2001: Jaroslaw P Maciejewski; dean follmann; Ryotaro Nakamura; Yogen Saunthararajah; C E Rivera; Toni Simonis; Kevin E Brown; John A Barrett; Neal S Young
Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome.
Blood 2001;98(13):3513-9.
2001: J P Maciejewski; C Rivera; H Kook; D Dunn; Neal S Young
Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol-anchored protein-deficient clones.
British journal of haematology 2001;115(4):1015-22.
2001: Hoon Kook; Weihua Zeng; C Guibin; Martha Kirby; Neal S Young; Jaroslaw P Maciejewski
Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia.
Experimental hematology 2001;29(11):1270-7.
2001: Ryotaro Nakamura; Erkut Bahceci; Elizabeth J Read; Susan F Leitman; Charles S Carter; Richard Childs; Cynthia E Dunbar; R Gress; R Altemus; Neal S Young; A John Barrett
Transplant dose of CD34(+) and CD3(+) cells predicts outcome in patients with haematological malignancies undergoing T cell-depleted peripheral blood stem cell transplants with delayed donor lymphocyte add-back.
British journal of haematology 2001;115(1):95-104.
2001: Weihua Zeng; Jaroslaw P Maciejewski; Guibin Chen; Neal S Young
Limited heterogeneity of T cell receptor BV usage in aplastic anemia.
The Journal of clinical investigation 2001;108(5):765-73.
2001: Tim H Brümmendorf; J P Maciejewski; Jennifer Mak; Neal S Young; Peter M Lansdorp
Telomere length in leukocyte subpopulations of patients with aplastic anemia.
Blood 2001;97(4):895-900.
2001: Yogen Saunthararajah; J L Molldrem; Mary Rivera; A Williams; Maryalice Stetler-Stevenson; Lynn Sorbara; Neal S Young; John A Barrett
Coincident myelodysplastic syndrome and T-cell large granular lymphocytic disease: clinical and pathophysiological features.
British journal of haematology 2001;112(1):195-200.
2001: Kevin E Brown; Neal S Young; Barbara M Alving; L H Barbosa
Parvovirus B19: implications for transfusion medicine. Summary of a workshop.
Transfusion 2001;41(1):130-5.
2000: John F Tisdale; Daniel E Dunn; Nancy Geller; M Plante; Olga Nunez; C E Dunbar; A John Barrett; THOMAS WALSH; Stephen Rosenfeld; Neal S Young
High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial.
Lancet 2000;356(9241):1554-9.
2000: Jaroslaw P Maciejewski; Sonnie Kim; Elaine M Sloand; Carmine Selleri; Neal S Young
Sustained long-term hematologic recovery despite a marked quantitative defect in the stem cell compartment of patients with aplastic anemia after immunosuppressive therapy.
American journal of hematology 2000;65(2):123-31.
2000: Richard Childs; A Chernoff; N Contentin; Erkut Bahceci; D Schrump; Susan F Leitman; Elizabeth J Read; John F Tisdale; Cynthia Dunbar; W M Linehan; Neal S Young; A John Barrett
Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation.
The New England journal of medicine 2000;343(11):750-8.
2000: Neal S Young; Jaroslaw P Maciejewski
Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?".
The Journal of clinical investigation 2000;106(5):637-41.
2000: Z Liu; R E Donahue; Neal S Young; Kevin E Brown
Sequencing and characterization of A-2 plaque virus: A new member of the Picornaviridae family.
Virology 2000;272(1):168-76.
2000: Elaine M Sloand; Sonnie Kim; Jaroslaw P Maciejewski; Frits van Rhee; A Chaudhuri; John Barrett; Neal S Young
Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo.
Blood 2000;95(7):2269-74.
2000: A Handa; R F Jubran; B Dickstein; A Boylan; N L Luban; Neal S Young; Kevin E Brown
GB virus C/Hepatitis G virus infection is frequent in American children and young adults.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30(3):569-71.
2000: E Bahçeci; Elizabeth J Read; Susan F Leitman; Richard Childs; Cynthia Dunbar; Neal S Young; A John Barrett
CD34+ cell dose predicts relapse and survival after T-cell-depleted HLA-identical haematopoietic stem cell transplantation (HSCT) for haematological malignancies.
British journal of haematology 2000;108(2):408-14.
2000: A Handa; B Dickstein; Neal S Young; Kevin E Brown
Prevalence of the newly described human circovirus, TTV, in United States blood donors.
Transfusion 2000;40(2):245-51.
2000: Kevin E Brown; Neal S Young
Epidemiology and pathology of erythroviruses.
Contributions to microbiology 2000;4():107-22.
2000: Neal S Young
Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia.
Seminars in hematology 2000;37(1):3-14.
2000: Neelam Giri; E Kang; John F Tisdale; dean follmann; Mary Rivera; G N Schwartz; Sonnie Kim; Neal S Young; Margaret E Rick; Cynthia E Dunbar
Clinical and laboratory evidence for a trilineage haematopoietic defect in patients with refractory Diamond-Blackfan anaemia.
British journal of haematology 2000;108(1):167-75.
1999: Richard Childs; E Clave; N Contentin; D Jayasekera; Nancy Hensel; Susan F Leitman; Elizabeth J Read; Charles Carter; Erkut Bahceci; Neal S Young; A John Barrett
Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses.
Blood 1999;94(9):3234-41.
1999: Daniel E Dunn; P Tanawattanacharoen; P Boccuni; Shoichi Nagakura; SW Green; M R Kirby; M S Kumar; Stephen Rosenfeld; Neal S Young
Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes.
Annals of internal medicine 1999;131(6):401-8.
1999: Johnson Ming-Yu Liu; Sonnie Kim; Elizabeth J Read; Makoto Futaki; I Dokal; C S Carter; Susan F Leitman; M Pensiero; Neal S Young; Christopher E Walsh
Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC).
Human gene therapy 1999;10(14):2337-46.
1999: Elaine M Sloand; P N Kumar; Sonnie Kim; A Chaudhuri; Frank F Weichold; Neal S Young
Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo.
Blood 1999;94(3):1021-7.
1999: Neal S Young
Acquired aplastic anemia.
JAMA : the journal of the American Medical Association 1999;282(3):271-8.
1999: JM Yu; RV Emmons; Yutaka Hanazono; Stephanie Sellers; Neal S Young; Cynthia E Dunbar
Expression of interferon-gamma by stromal cells inhibits murine long-term repopulating hematopoietic stem cell activity.
Experimental hematology 1999;27(5):895-903.
1999: Daniel E Dunn; R E Ware; C J Parker; H O Mishoe; Neal S Young
Research directions in paroxysmal nocturnal hemoglobinuria.
Immunology today 1999;20(4):168-71.
1998: Elaine M Sloand; Jaroslaw P Maciejewski; D Dunn; Joel Moss; B Brewer; Martha Kirby; Neal S Young
Correction of the PNH defect by GPI-anchored protein transfer.
Blood 1998;92(11):4439-45.
1998: Elaine M Sloand; Neal S Young; T Sato; S Kim; Jaroslaw P Maciejewski
Inhibition of interleukin-1beta-converting enzyme in human hematopoietic progenitor cells results in blockade of cytokine-mediated apoptosis and expansion of their proliferative potential.
Experimental hematology 1998;26(11):1093-9.
1998: T Sato; Sonnie Kim; Carmine Selleri; Neal S Young; Jaroslaw P Maciejewski
Measurement of secondary colony formation after 5 weeks in long-term cultures in patients with myelodysplastic syndrome.
Leukemia 1998;12(8):1187-94.
1998: A John Barrett; DA Mavroudis; John F Tisdale; Jeffrey J Molldrem; E Clave; Cynthia Dunbar; M Cottler-Fox; Sheila Phang; Charles Carter; P Okunnieff; Neal S Young; Elizabeth J Read
T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect.
Bone marrow transplantation 1998;21(6):543-51.
1998: Frank F Weichold; Davide Zella; Oxana Barabitskaja; Jaroslaw P Maciejewski; Daniel E Dunn; Elaine M Sloand; Neal S Young
Neither human immunodeficiency virus-1 (HIV-1) nor HIV-2 infects most-primitive human hematopoietic stem cells as assessed in long-term bone marrow cultures.
Blood 1998;91(3):907-15.
1998: Elaine M Sloand; Jaroslaw P Maciejewski; T Sato; J Bruny; P Kumar; Sonnie Kim; Frank F Weichold; Neal S Young
The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection.
The Journal of clinical investigation 1998;101(1):195-201.
1997: T Sato; Carmine Selleri; Neal S Young; Jaroslaw P Maciejewski
Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-gamma due to phosphorylation of Stat1 and Stat3.
Blood 1997;90(12):4749-58.
1997: Jeffrey J Molldrem; M Caples; DA Mavroudis; M Plante; Neal S Young; A John Barrett
Antithymocyte globulin for patients with myelodysplastic syndrome.
British journal of haematology 1997;99(3):699-705.
1997: Elaine M Sloand; Neal S Young; T Sato; P Kumar; Sonnie Kim; Frank F Weichold; Jaroslaw P Maciejewski
Secondary colony formation after long-term bone marrow culture using peripheral blood and bone marrow of HIV-infected patients.
AIDS (London, England) 1997;11(13):1547-53.
1997: Johnson Ming-Yu Liu; Neal S Young; Christopher E Walsh; M Cottler-Fox; Charles Carter; Cynthia Dunbar; A J Barrett; RV Emmons
Retroviral mediated gene transfer of the Fanconi anemia complementation group C gene to hematopoietic progenitors of group C patients.
Human gene therapy 1997;8(14):1715-30.
1997: Janis L Abkowitz; Kevin E Brown; Robert W Wood; N L Kovach; SW Green; Neal S Young
Clinical relevance of parvovirus B19 as a cause of anemia in patients with human immunodeficiency virus infection.
The Journal of infectious diseases 1997;176(1):269-73.
1997: MG O'Sullivan; Deborah K Anderson; J A Goodrich; H Tulli; SW Green; Neal S Young; Kevin E Brown
Experimental infection of cynomolgus monkeys with simian parvovirus.
Journal of virology 1997;71(6):4517-21.
1997: Neal S Young; Jaroslaw Maciejewski
The pathophysiology of acquired aplastic anemia.
The New England journal of medicine 1997;336(19):1365-72.
1997: Kevin E Brown; Susan Wong; Neal S Young
Prevalence of GBV-C/HGV, a novel 'hepatitis' virus, in patients with aplastic anaemia.
British journal of haematology 1997;97(2):492-6.
1997: T Sato; Carmine Selleri; S Anderson; Neal S Young; Jaroslaw P Maciejewski
Expression and modulation of cellular receptors for interferon-gamma, tumour necrosis factor, and Fas on human bone marrow CD34+ cells.
British journal of haematology 1997;97(2):356-65.
1997: Kevin E Brown; John F Tisdale; A John Barrett; C E Dunbar; Neal S Young
Hepatitis-associated aplastic anemia.
The New England journal of medicine 1997;336(15):1059-64.
1997: MP Devetten; Johnson Ming-Yu Liu; V Ling; Frank F Weichold; J Yu; M Edward Medof; Neal S Young; Daniel E Dunn
Paroxysmal nocturnal hemoglobinuria: new insights from murine Pig-a-deficient hematopoiesis.
Proceedings of the Association of American Physicians 1997;109(2):99-110.
1997: Elaine M Sloand; Neal S Young; P Kumar; Frank F Weichold; T Sato; Jaroslaw P Maciejewski
Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication.
Blood 1997;89(4):1357-63.
1997: Jaroslaw P Maciejewski; Elaine M Sloand; T Sato; S Anderson; Neal S Young
Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone.
Blood 1997;89(4):1173-81.
1997: Kevin E Brown; Susan Wong; M Buu; T V Binh; T V Be; Neal S Young
High prevalence of GB virus C/hepatitis G virus in healthy persons in Ho Chi Minh City, Vietnam.
The Journal of infectious diseases 1997;175(2):450-3.
1997: Kevin E Brown; Neal S Young
Human parvovirus B19 infections in infants and children.
Advances in pediatric infectious diseases 1997;13():101-26.
1997: M H Qazilbash; Johnson Ming-Yu Liu; Adrianna Vlachos; Steven Fruchtman; H Messner; A Zipursky; BLANCHE ALTER; Neal S Young
A new syndrome of familial aplastic anemia and chronic liver disease.
Acta haematologica 1997;97(3):164-7.
1997: Kevin E Brown; Neal S Young
Parvovirus B19 in human disease.
Annual review of medicine 1997;48():59-67.
1996: Jaroslaw P Maciejewski; Neal S Young; M Yu; S M Anderson; Elaine M Sloand
Analysis of the expression of glycosylphosphatidylinositol anchored proteins on platelets from patients with paroxysmal nocturnal hemoglobinuria.
Thrombosis research 1996;83(6):433-47.
1996: Jaroslaw P Maciejewski; Carmine Selleri; T Sato; S Anderson; Neal S Young
A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia.
Blood 1996;88(6):1983-91.
1996: Daniel E Dunn; J Yu; S Nagarajan; M Devetten; Frank F Weichold; M E Medof; Neal S Young; Johnson Ming-Yu Liu
A knock-out model of paroxysmal nocturnal hemoglobinuria: Pig-a(-) hematopoiesis is reconstituted following intercellular transfer of GPI-anchored proteins.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7938-43.
1996: S Muramatsu; H Mizukami; Neal S Young; Kevin E Brown
Nucleotide sequencing and generation of an infectious clone of adeno-associated virus 3.
Virology 1996;221(1):208-17.
1996: MG O'Sullivan; Deborah K Anderson; J E Lund; W P Brown; SW Green; Neal S Young; Kevin E Brown
Clinical and epidemiological features of simian parvovirus infection in cynomolgus macaques with severe anemia.
Laboratory animal science 1996;46(3):291-7.
1996: Carmine Selleri; Jaroslaw P Maciejewski; T Sato; Neal S Young
Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition.
Blood 1996;87(10):4149-57.
1996: RV Emmons; D M Reid; R L Cohen; G Meng; Neal S Young; Cynthia E Dunbar; N R Shulman
Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction.
Blood 1996;87(10):4068-71.
1996: Neal S Young
Parvovirus infection and its treatment.
Clinical and experimental immunology 1996;104 Suppl 1():26-30.
1996: Kevin E Brown; Neal S Young
Parvoviruses and bone marrow failure.
Stem cells (Dayton, Ohio) 1996;14(2):151-63.
1996: H Mizukami; Neal S Young; Kevin E Brown
Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein.
Virology 1996;217(1):124-30.
1996: Neal S Young
Immune pathophysiology of acquired aplastic anaemia.
European journal of haematology. Supplementum 1996;60():55-9.
1996: Neal S Young
Drug-related blood dyscrasias. Introduction.
European journal of haematology. Supplementum 1996;60():6-8.
1995: T Sato; Carmine Selleri; Neal S Young; Jaroslaw P Maciejewski
Hematopoietic inhibition by interferon-gamma is partially mediated through interferon regulatory factor-1.
Blood 1995;86(9):3373-80.
1995: M Kawase; M Momoeda; Neal S Young; Sachiko Kajigaya
Modest truncation of the major capsid protein abrogates B19 parvovirus capsid formation.
Journal of virology 1995;69(10):6567-71.
1995: Kevin E Brown; Neal S Young
Parvovirus B19 infection and hematopoiesis.
Blood reviews 1995;9(3):176-82.
1995: Jaroslaw P Maciejewski; Carmine Selleri; T Sato; S Anderson; Neal S Young
Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia.
British journal of haematology 1995;91(1):245-52.
1995: M Kawase; M Momoeda; Neal S Young; Sachiko Kajigaya
Most of the VP1 unique region of B19 parvovirus is on the capsid surface.
Virology 1995;211(2):359-66.
1995: Jaroslaw P Maciejewski; Carmine Selleri; T Sato; H J Cho; L K Keefer; C F Nathan; Neal S Young
Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha.
The Journal of clinical investigation 1995;96(2):1085-92.
1995: Neal S Young
Aplastic anaemia.
Lancet 1995;346(8969):228-32.
1995: Kevin E Brown; SW Green; MG O'Sullivan; Neal S Young
Cloning and sequencing of the simian parvovirus genome.
Virology 1995;210(2):314-22.
1995: Kevin E Brown; SW Green; Neal S Young
Goose parvovirus--an autonomous member of the dependovirus genus?
Virology 1995;210(2):283-91.
1995: Jaroslaw P Maciejewski; Frank F Weichold; Neal S Young; Andrea Cara; Davide Zella; Marvin Reitz; Robert C Gallo
Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro.
Nature medicine 1995;1(7):667-73.
1995: Neal S Young; A John Barrett
The treatment of severe acquired aplastic anemia.
Blood 1995;85(12):3367-77.
1995: Stephen Rosenfeld; J Kimball; D Vining; Neal S Young
Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia.
Blood 1995;85(11):3058-65.
1995: G Gallinella; S M Anderson; Neal S Young; Kevin E Brown
Human parvovirus B19 can infect cynomolgus monkey marrow cells in tissue culture.
Journal of virology 1995;69(6):3897-9.
1995: Jaroslaw P Maciejewski; Carmine Selleri; S Anderson; Neal S Young
Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro.
Blood 1995;85(11):3183-90.
1995: M Momoeda; M Kawase; Neal S Young; Sachiko Kajigaya
Purification of functional recombinant YY1 expressed in Sf9 insect cells.
Protein expression and purification 1995;6(2):169-75.
1995: S Anderson; M Momoeda; M Kawase; Sachiko Kajigaya; Neal S Young
Peptides derived from the unique region of B19 parvovirus minor capsid protein elicit neutralizing antibodies in rabbits.
Virology 1995;206(1):626-32.
1994: Johnson Ming-Yu Liu; M Buchwald; Christopher E Walsh; Neal S Young
Fanconi anemia and novel strategies for therapy.
Blood 1994;84(12):3995-4007.
1994: M Momoeda; S Wong; M Kawase; Neal S Young; Sachiko Kajigaya
A putative nucleoside triphosphate-binding domain in the nonstructural protein of B19 parvovirus is required for cytotoxicity.
Journal of virology 1994;68(12):8443-6.
1994: K R Hartman; Kevin E Brown; SW Green; Neal S Young
Lack of evidence for parvovirus B19 viraemia in children with chronic neutropenia.
British journal of haematology 1994;88(4):895-6.
1994: G Gallinella; Neal S Young; Kevin E Brown
In situ hybridisation and in situ polymerase chain reaction detection of parvovirus B19 DNA within cells.
Journal of virological methods 1994;50(1-3):67-74.
1994: M Momoeda; M Kawase; Stephen M Jane; K Miyamura; Neal S Young; Sachiko Kajigaya
The transcriptional regulator YY1 binds to the 5'-terminal region of B19 parvovirus and regulates P6 promoter activity.
Journal of virology 1994;68(11):7159-68.
1994: Jaroslaw P Maciejewski; Frank F Weichold; Neal S Young
HIV-1 suppression of hematopoiesis in vitro mediated by envelope glycoprotein and TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):4303-10.
1994: J L Miller; Robert E Donahue; Stephanie Sellers; R Jude Samulski; Neal S Young; A W Nienhuis
Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):10183-7.
1994: Christopher E Walsh; A W Nienhuis; R Jude Samulski; M G Brown; J L Miller; Neal S Young; Johnson Ming-Yu Liu
Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector.
The Journal of clinical investigation 1994;94(4):1440-8.
1994: Jaroslaw P Maciejewski; J R Hibbs; S Anderson; P Katevas; Neal S Young
Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure.
Experimental hematology 1994;22(11):1102-10.
1994: S Goodman; Xiaodong Xiao; Robert E Donahue; A Moulton; J Miller; Christopher E Walsh; Neal S Young; R Jude Samulski; A W Nienhuis
Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells.
Blood 1994;84(5):1492-500.
1994: K Miyamura; Sachiko Kajigaya; M Momoeda; S J Smith-Gill; Neal S Young
Parvovirus particles as platforms for protein presentation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8507-11.
1994: Robert A Brodsky; S Hasegawa; E Fibach; Cynthia E Dunbar; Neal S Young; G P Rodgers
Acquired sideroblastic anaemia following progesterone therapy.
British journal of haematology 1994;87(4):859-62.
1994: Christopher E Walsh; Markus Grompe; E Vanin; M Buchwald; Neal S Young; A W Nienhuis; Johnson Ming-Yu Liu
A functionally active retrovirus vector for gene therapy in Fanconi anemia group C.
Blood 1994;84(2):453-9.
1994: S Wong; M Momoeda; A Field; Sachiko Kajigaya; Neal S Young
Formation of empty B19 parvovirus capsids by the truncated minor capsid protein.
Journal of virology 1994;68(7):4690-4.
1994: Jaroslaw P Maciejewski; S Anderson; P Katevas; Neal S Young
Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure.
British journal of haematology 1994;87(2):227-34.
1994: Kevin E Brown; J R Hibbs; G Gallinella; S M Anderson; E D Lehman; P McCarthy; Neal S Young
Resistance to parvovirus B19 infection due to lack of virus receptor (erythrocyte P antigen).
The New England journal of medicine 1994;330(17):1192-6.
1994: Kevin E Brown; SW Green; J Antunez de Mayolo; J A Bellanti; S D Smith; T J Smith; Neal S Young
Congenital anaemia after transplacental B19 parvovirus infection.
Lancet 1994;343(8902):895-6.
1994: MG O'Sullivan; D C Anderson; J D Fikes; F T Bain; C S Carlson; SW Green; Neal S Young; Kevin E Brown
Identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia. A paradigm of human B19 parvovirus infection.
The Journal of clinical investigation 1994;93(4):1571-6.
1994: Neal S Young
Agranulocytosis.
JAMA : the journal of the American Medical Association 1994;271(12):935-8.
1994: A Nisticò; Neal S Young
gamma-Interferon gene expression in the bone marrow of patients with aplastic anemia.
Annals of internal medicine 1994;120(6):463-9.
1994: Kevin E Brown; Neal S Young; Johnson Ming-Yu Liu
Molecular, cellular and clinical aspects of parvovirus B19 infection.
Critical reviews in oncology/hematology 1994;16(1):1-31.
1994: Stephen Rosenfeld; Neal S Young; D Alling; J Ayub; William Saxinger
Subunit interaction in B19 parvovirus empty capsids.
Archives of virology 1994;136(1-2):9-18.
1993: Johnson Ming-Yu Liu; A D Auerbach; S M Anderson; SW Green; Neal S Young
A trial of recombinant human superoxide dismutase in patients with Fanconi anaemia.
British journal of haematology 1993;85(2):406-8.
1993: Kevin E Brown; S M Anderson; Neal S Young
Erythrocyte P antigen: cellular receptor for B19 parvovirus.
Science (New York, N.Y.) 1993;262(5130):114-7.
1993: Jaroslaw P Maciejewski; E E Bruening; Robert E Donahue; Stephanie Sellers; Charles Carter; Neal S Young; S St Jeor
Infection of mononucleated phagocytes with human cytomegalovirus.
Virology 1993;195(2):327-36.
1993: T Saikawa; S Anderson; M Momoeda; Sachiko Kajigaya; Neal S Young
Neutralizing linear epitopes of B19 parvovirus cluster in the VP1 unique and VP1-VP2 junction regions.
Journal of virology 1993;67(6):3004-9.
1993: Geetha P Bansal; J A Hatfield; F E Dunn; Andrew Kramer; F Brady; C H Riggin; Marc S Collett; K Yoshimoto; Sachiko Kajigaya; Neal S Young
Candidate recombinant vaccine for human B19 parvovirus.
The Journal of infectious diseases 1993;167(5):1034-44.
1993: S Shimomura; S Wong; Kevin E Brown; N Komatsu; Sachiko Kajigaya; Neal S Young
Early and late gene expression in UT-7 cells infected with B19 parvovirus.
Virology 1993;194(1):149-56.
1992: Jaroslaw P Maciejewski; Johnson Ming-Yu Liu; SW Green; Christopher E Walsh; Mark Plumb; I B Pragnell; Neal S Young
Expression of stem cell inhibitor (SCI) gene in patients with bone marrow failure.
Experimental hematology 1992;20(9):1112-7.
1992: Johnson Ming-Yu Liu; SW Green; T Shimada; Neal S Young
A block in full-length transcript maturation in cells nonpermissive for B19 parvovirus.
Journal of virology 1992;66(8):4686-92.
1992: Christopher E Walsh; Johnson Ming-Yu Liu; Xiaodong Xiao; Neal S Young; A W Nienhuis; R Jude Samulski
Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7257-61.
1992: Jaroslaw P Maciejewski; E E Bruening; Robert E Donahue; Edward Mocarski; Neal S Young; S C St Jeor
Infection of hematopoietic progenitor cells by human cytomegalovirus.
Blood 1992;80(1):170-8.
1992: D E Koziol; G Kurtzman; J Ayub; Neal S Young; D K Henderson
Nosocomial human parvovirus B19 infection: lack of transmission from a chronically infected patient to hospital staff.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 1992;13(6):343-8.
1992: Stephen Rosenfeld; K Yoshimoto; Sachiko Kajigaya; S Anderson; Neal S Young; A Field; Paul Warrener; Geetha P Bansal; Marc S Collett
Unique region of the minor capsid protein of human parvovirus B19 is exposed on the virion surface.
The Journal of clinical investigation 1992;89(6):2023-9.
1992: J R Hibbs; S Issaragrisil; Neal S Young
High prevalence of hepatitis C viremia among aplastic anemia patients and controls from Thailand.
The American journal of tropical medicine and hygiene 1992;46(5):564-70.
1992: J R Hibbs; Norbert Frickhofen; Stephen Rosenfeld; S M Feinstone; S Kojima; A Bacigalupo; A Locasciulli; Andreas G Tzakis; Harvey Alter; Neal S Young
Aplastic anemia and viral hepatitis. Non-A, Non-B, Non-C?
JAMA : the journal of the American Medical Association 1992;267(15):2051-4.
1992: Neal S Young
The problem of clonality in aplastic anemia: Dr Dameshek's riddle, restated.
Blood 1992;79(6):1385-92.
1992: S Shimomura; N Komatsu; Norbert Frickhofen; S Anderson; Sachiko Kajigaya; Neal S Young
First continuous propagation of B19 parvovirus in a cell line.
Blood 1992;79(1):18-24.
1992: Christopher E Walsh; Johnson Ming-Yu Liu; S M Anderson; J L Rossio; A W Nienhuis; Neal S Young
A trial of recombinant human interleukin-1 in patients with severe refractory aplastic anaemia.
British journal of haematology 1992;80(1):106-10.
1991: K Yoshimoto; S Rosenfeld; Norbert Frickhofen; D Kennedy; R Hills; Sachiko Kajigaya; Neal S Young
A second neutralizing epitope of B19 parvovirus implicates the spike region in the immune response.
Journal of virology 1991;65(12):7056-60.
1991: Johnson Ming-Yu Liu; SW Green; Y S Hao; Kevin T McDonagh; Neal S Young; T Shimada
Upstream sequences within the terminal hairpin positively regulate the P6 promoter of B19 parvovirus.
Virology 1991;185(1):39-47.
1991: Norbert Frickhofen; Neal S Young
A rapid method of sample preparation for detection of DNA viruses in human serum by polymerase chain reaction.
Journal of virological methods 1991;35(1):65-72.
1991: Cynthia E Dunbar; D A Smith; J Kimball; L Garrison; A W Nienhuis; Neal S Young
Treatment of Diamond-Blackfan anaemia with haematopoietic growth factors, granulocyte-macrophage colony stimulating factor and interleukin 3: sustained remissions following IL-3.
British journal of haematology 1991;79(2):316-21.
1991: Sachiko Kajigaya; H Fujii; A Field; S Anderson; S Rosenfeld; L J Anderson; T Shimada; Neal S Young
Self-assembled B19 parvovirus capsids, produced in a baculovirus system, are antigenically and immunogenically similar to native virions.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4646-50.
1991: Stephen Rosenfeld; Neal S Young
Viruses and bone marrow failure.
Blood reviews 1991;5(2):71-7.
1991: Johnson Ming-Yu Liu; H Fujii; SW Green; N Komatsu; Neal S Young; T Shimada
Indiscriminate activity from the B19 parvovirus p6 promoter in nonpermissive cells.
Virology 1991;182(1):361-4.
1991: Neal S Young; S Rosenfeld; J Antunez-de-Mayolo; J Hibbs; Johnson Ming-Yu Liu; Jaroslaw P Maciejewski; S St Jeor; S Shimomura; Sachiko Kajigaya
Viruses and bone marrow failure.
Schweizerische medizinische Wochenschrift. Supplementum 1991;43():28-32.
1990: Norbert Frickhofen; Neal S Young
Polymerase chain reaction for detection of parvovirus B19 in immunodeficient patients with anemia.
Behring Institute Mitteilungen 1990;(85):46-54.
1990: Neal S Young
Flaviviruses and bone marrow failure.
JAMA : the journal of the American Medical Association 1990;263(22):3065-8.
1990: Norbert Frickhofen; Johnson Ming-Yu Liu; Neal S Young
Etiologic mechanisms of hematopoietic failure.
The American journal of pediatric hematology/oncology 1990;12(4):385-95.
1989: Norbert Frickhofen; Neal S Young
Persistent parvovirus B19 infections in humans.
Microbial pathogenesis 1989;7(5):319-27.
1989: Sachiko Kajigaya; T Shimada; S Fujita; Neal S Young
A genetically engineered cell line that produces empty capsids of B19 (human) parvovirus.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7601-5.
1989: G J Kurtzman; B J Cohen; A M Field; R Oseas; R. Michael Blaese; Neal S Young
Immune response to B19 parvovirus and an antibody defect in persistent viral infection.
The Journal of clinical investigation 1989;84(4):1114-23.
1989: S Nakao; C J Lai; Neal S Young
Dengue virus, a flavivirus, propagates in human bone marrow progenitors and hematopoietic cell lines.
Blood 1989;74(4):1235-40.
1989: G Kurtzman; Norbert Frickhofen; J Kimball; D W Jenkins; A W Nienhuis; Neal S Young
Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy.
The New England journal of medicine 1989;321(8):519-23.
1989: G J Kurtzman; L Platanias; L Lustig; Norbert Frickhofen; Neal S Young
Feline parvovirus propagates in cat bone marrow cultures and inhibits hematopoietic colony formation in vitro.
Blood 1989;74(1):71-81.
1989: E M Leonard; E Raefsky; P Griffith; J Kimball; A W Nienhuis; Neal S Young
Cyclosporine therapy of aplastic anaemia, congenital and acquired red cell aplasia.
British journal of haematology 1989;72(2):278-84.
1989: Neal S Young; B Baranski; G Kurtzman
The immune system as mediator of virus-associated bone marrow failure: B19 parvovirus and Epstein-Barr virus.
Annals of the New York Academy of Sciences 1989;554():75-80.
1988: G J Kurtzman; B Cohen; Paul A Meyers; A Amunullah; Neal S Young
Persistent B19 parvovirus infection as a cause of severe chronic anaemia in children with acute lymphocytic leukaemia.
Lancet 1988;2(8621):1159-62.
1988: B Baranski; G Armstrong; J T Truman; G V Quinnan; Stephen E Straus; Neal S Young
Epstein-Barr virus in the bone marrow of patients with aplastic anemia.
Annals of internal medicine 1988;109(9):695-704.
1988: G J Kurtzman; P Gascon; M Caras; B Cohen; Neal S Young
B19 parvovirus replicates in circulating cells of acutely infected patients.
Blood 1988;71(5):1448-54.
1988: Leonard Bielory; P Gascon; T J Lawley; Neal S Young; M M Frank
Human serum sickness: a prospective analysis of 35 patients treated with equine anti-thymocyte globulin for bone marrow failure.
Medicine 1988;67(1):40-57.
1988: B G Baranski; Neal S Young
Autoimmune aspects of aplastic anemia.
In vivo (Athens, Greece) 1988;2(1):91-4.
1987: G J Kurtzman; K Ozawa; B Cohen; G Hanson; R Oseas; Neal S Young
Chronic bone marrow failure due to persistent B19 parvovirus infection.
The New England journal of medicine 1987;317(5):287-94.
1987: Neal S Young; E Leonard; L Platanias
Lymphocytes and lymphokines in aplastic anemia: pathogenic role and implications for pathogenesis.
Blood cells 1987;13(1-2):87-100.
1986: Leonard Bielory; P Gascon; T J Lawley; A Nienhuis; M M Frank; Neal S Young
Serum sickness and haematopoietic recovery with antithymocyte globulin in bone marrow failure patients.
British journal of haematology 1986;63(4):729-36.
1985: T J Lawley; Leonard Bielory; P Gascon; K B Yancey; Neal S Young; M M Frank
A study of human serum sickness.
The Journal of investigative dermatology 1985;85(1 Suppl):129s-132s.
1985: P Gascon; N C Zoumbos; G Scala; J Y Djeu; J G Moore; Neal S Young
Lymphokine abnormalities in aplastic anemia: implications for the mechanism of action of antithymocyte globulin.
Blood 1985;65(2):407-13.
1985: N C Zoumbos; P Gascon; J Y Djeu; Neal S Young
Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(1):188-92.
1984: T J Lawley; Leonard Bielory; P Gascon; K B Yancey; Neal S Young; M M Frank
A prospective clinical and immunologic analysis of patients with serum sickness.
The New England journal of medicine 1984;311(22):1407-13.
1984: T J Lawley; Leonard Bielory; P Gascon; K B Yancey; Neal S Young; M M Frank
Human serum sickness.
Transactions of the Association of American Physicians 1984;97():49-55.
1982: D Vembu; Neal S Young; M Willing; E Church; L Sanders-Haigh; W French Anderson
Regulation of human globin gene expression in mouse erythroleukemia x human fibroblast hybrid cells.
Somatic cell genetics 1982;8(2):163-78.