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Neal Young
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54
Maciejewski, Jaroslaw
42
Kajigaya, Sachiko
36
Sloand, Elaine
35
Brown, Kevin
20
Barrett, John
20
Risitano, Antonio
19
Liu, Johnson
17
Calado, Rodrigo
16
Zeng, Weihua
14
Green, SW
13
Nunez, Olga
12
Chen, Guibin
11
Chen, Jichun
11
Kim, Sonnie
11
Scheinberg, Phillip
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All Publications
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2009: Calado R T; Regal J A; Kajigaya S; Young N S
Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations.
European journal of clinical investigation 2009;39(11):1025-32.
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2009: Calado Rodrigo T; Yewdell William T; Wilkerson Keisha L; Regal Joshua A; Kajigaya Sachiko; Stratakis Constantine A; Young Neal S
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Blood 2009;114(11):2236-43.
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2009: Savage Sharon A; Dokal Inderjeet; Armanios Mary; Aubert Geraldine; Cowen Edward W; Domingo Demetrio L; Giri Neelam; Greene Mark H; Orchard Paul J; Tolar Jakub; Tsilou Ekaterini; Van Waes Carter; Wong Judy M Y; Young Neal S; Alter Blanche P
Dyskeratosis congenita: the first NIH clinical research workshop.
Pediatric blood & cancer 2009;53(3):520-3.
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2009: Valdez Jessica M; Scheinberg Phillip; Young Neal S; Walsh Thomas J
Infections in patients with aplastic anemia.
Seminars in hematology 2009;46(3):269-76.
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2009: Takaku Tomoiku; Calado Rodrigo T; Kajigaya Sachiko; Young Neal S
Interleukin-23 receptor (IL-23R) gene polymorphisms in acquired aplastic anemia.
Annals of hematology 2009;88(7):653-7.
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2009: Sarcon Annahita K; Desierto Marie J; Zhou Wenjun; Visconte Valeria; Gibellini Federica; Chen Jichun; Young Neal S
Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure.
Experimental hematology 2009;37(4):477-86.
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2009: Omokaro Stephanie O; Desierto Marie J; Eckhaus Michael A; Ellison Felicia M; Chen Jichun; Young Neal S
Lymphocytes with aberrant expression of Fas or Fas ligand attenuate immune bone marrow failure in a mouse model.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3414-22.
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2009: Scheinberg Phillip; Wu Colin O; Nunez Olga; Scheinberg Priscila; Boss Carol; Sloand Elaine M; Young Neal S
Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study.
Haematologica 2009;94(3):348-54.
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2009: Tang Yong; Chen Jichun; Young Neal S
Expansion of haematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4.
British journal of haematology 2009;144(4):603-12.
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2009: Calado Rodrigo T; Regal Joshua A; Hills Mark; Yewdell William T; Dalmazzo Leandro F; Zago Marco A; Lansdorp Peter M; Hogge Donna; Chanock Stephen J; Estey Elihu H; Falcão Roberto P; Young Neal S
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1187-92.
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2009: Young Neal S
Paroxysmal nocturnal hemoglobinuria and myelodysplastic syndromes: clonal expansion of PIG-A-mutant hematopoietic cells in bone marrow failure.
Haematologica 2009;94(1):3-7.
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2009: Scheinberg Phillip; Wu Colin O; Nunez Olga; Young Neal S
Predicting response to immunosuppressive therapy and survival in severe aplastic anaemia.
British journal of haematology 2009;144(2):206-16.
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2008: Sloand Elaine M; Pfannes Loretta; Scheinberg Phillip; More Kenneth; Wu Colin O; Horne McDonald; Young Neal S
Increased soluble urokinase plasminogen activator receptor (suPAR) is associated with thrombosis and inhibition of plasmin generation in paroxysmal nocturnal hemoglobinuria (PNH) patients.
Experimental hematology 2008;36(12):1616-24.
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2008: Scheinberg Phillip; Wu Colin O; Nunez Olga; Young Neal S
Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine.
The Journal of pediatrics 2008;153(6):814-9.
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2008: Chen Jichun; Ellison Felicia M; Keyvanfar Keyvan; Omokaro Stephanie O; Desierto Marie J; Eckhaus Michael A; Young Neal S
Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice.
Experimental hematology 2008;36(10):1236-43.
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2008: Schubert Jörg; Hillmen Peter; Röth Alexander; Young Neal S; Elebute Modupe O; Szer Jeffrey; Gianfaldoni Giacomo; Socié Gérard; Browne Paul; Geller Robert; Rother Russell P; Muus Petra;
Eculizumab, a terminal complement inhibitor, improves anaemia in patients with paroxysmal nocturnal haemoglobinuria.
British journal of haematology 2008;142(2):263-72.
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2008: Young Neal S; Scheinberg Phillip; Calado Rodrigo T
Aplastic anemia.
Current opinion in hematology 2008;15(3):162-8.
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2008: Filippone Claudia; Zhi Ning; Wong Susan; Lu Jun; Kajigaya Sachiko; Gallinella Giorgio; Kakkola Laura; Söderlund-Venermo Maria; Young Neal S; Brown Kevin E
VP1u phospholipase activity is critical for infectivity of full-length parvovirus B19 genomic clones.
Virology 2008;374(2):444-52.
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2008: Calado Rodrigo T; Young Neal S
Telomere maintenance and human bone marrow failure.
Blood 2008;111(9):4446-55.
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2008: Young Neal S; Kaufman David W
The epidemiology of acquired aplastic anemia.
Haematologica 2008;93(4):489-92.
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2008: Feng Xingmin; Kajigaya Sachiko; Solomou Elena E; Keyvanfar Keyvan; Xu Xiuli; Raghavachari Nalini; Munson Peter J; Herndon Thomas M; Chen Jichun; Young Neal S
Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro.
Blood 2008;111(7):3675-83.
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2008: Wong Susan; Zhi Ning; Filippone Claudia; Keyvanfar Keyvan; Kajigaya Sachiko; Brown Kevin E; Young Neal S
Ex vivo-generated CD36+ erythroid progenitors are highly permissive to human parvovirus B19 replication.
Journal of virology 2008;82(5):2470-6.
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2008: Brodsky Robert A; Young Neal S; Antonioli Elisabetta; Risitano Antonio M; Schrezenmeier Hubert; Schubert Jörg; Gaya Anna; Coyle Luke; de Castro Carlos; Fu Chieh-Lin; Maciejewski Jaroslaw P; Bessler Monica; Kroon Henk-André; Rother Russell P; Hillmen Peter
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.
Blood 2008;111(4):1840-7.
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2007: Amexis Georgios; Young Neal S
Multiple antigenic peptides as vaccine platform for the induction of humoral responses against dengue-2 virus.
Viral immunology 2007;20(4):657-63.
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2007: Hillmen Peter; Muus Petra; Dührsen Ulrich; Risitano Antonio M; Schubert Jörg; Luzzatto Lucio; Schrezenmeier Hubert; Szer Jeffrey; Brodsky Robert A; Hill Anita; Socié Gerard; Bessler Monica; Rollins Scott A; Bell Leonard; Rother Russell P; Young Neal S
Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.
Blood 2007;110(12):4123-8.
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2007: Baerlocher Gabriela M; Sloand Elaine M; Young Neal S; Lansdorp Peter M
Telomere length in paroxysmal nocturnal hemoglobinuria correlates with clone size.
Experimental hematology 2007;35(12):1777-81.
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2007: Yao Yong-Gang; Childs Richard W; Kajigaya Sachiko; McCoy J Philip; Young Neal S
Mitochondrial DNA sequence heterogeneity of single CD34+ cells after nonmyeloablative allogeneic stem cell transplantation.
Stem cells (Dayton, Ohio) 2007;25(10):2670-6.
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2007: Solomou Elena E; Rezvani Katayoun; Mielke Stephan; Malide Daniela; Keyvanfar Keyvan; Visconte Valeria; Kajigaya Sachiko; Barrett A John; Young Neal S
Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia.
Blood 2007;110(5):1603-6.
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2007: Calado Rodrigo T; Graf Solomon A; Wilkerson Keisha L; Kajigaya Sachiko; Ancliff Philip J; Dror Yigal; Chanock Stephen J; Lansdorp Peter M; Young Neal S
Mutations in the SBDS gene in acquired aplastic anemia.
Blood 2007;110(4):1141-6.
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2007: Gidvani Vinod; Ramkissoon Shakti; Sloand Elaine M; Young Neal S
Cytokine gene polymorphisms in acquired bone marrow failure.
American journal of hematology 2007;82(8):721-4.
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2007: Sloand Elaine M; Read Elizabeth J; Scheinberg Phillip; Tang Yong; More Kenneth; Leitman Susan F; Maciejewski Jaroslaw; Young Neal S
Mobilization, collection, and immunomagnetic selection of peripheral blood CD34 cells in recovered aplastic anemia patients.
Transfusion 2007;47(7):1250-3.
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2007: Solomou Elena E; Wong Susan; Visconte Valeria; Gibellini Federica; Young Neal S
Decreased TCR zeta-chain expression in T cells from patients with acquired aplastic anaemia.
British journal of haematology 2007;138(1):72-6.
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2007: Solomou Elena E; Gibellini Federica; Stewart Brian; Malide Daniela; Berg Maria; Visconte Valeria; Green Spencer; Childs Richard; Chanock Stephen J; Young Neal S
Perforin gene mutations in patients with acquired aplastic anemia.
Blood 2007;109(12):5234-7.
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2007: Graf S A; Calado R T; Kajigaya S; Young N S
RMRP mutations in hematological disorders.
Clinical genetics 2007;71(5):468-70.
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2007: Chen Jichun; Ellison Felicia M; Eckhaus Michael A; Smith Aleah L; Keyvanfar Keyvan; Calado Rodrigo T; Young Neal S
Minor antigen h60-mediated aplastic anemia is ameliorated by immunosuppression and the infusion of regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4159-68.
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2007: Scheinberg Phillip; Fischer Steven H; Li Li; Nunez Olga; Wu Colin O; Sloand Elaine M; Cohen Jeffrey I; Young Neal S; John Barrett A
Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia.
Blood 2007;109(8):3219-24.
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2007: Graf Solomon A; Calado Rodrigo T; Young Neal S
PTPN22 620W allele is not associated with aplastic anemia.
American journal of hematology 2007;82(4):291-2.
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2007: Sloand Elaine M; Pfannes Loretta; Chen Gubin; Shah Simant; Solomou Elena E; Barrett John; Young Neal S
CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins.
Blood 2007;109(6):2399-405.
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2007: Yao Yong-Gang; Ellison Felicia M; McCoy J Philip; Chen Jichun; Young Neal S
Age-dependent accumulation of mtDNA mutations in murine hematopoietic stem cells is modulated by the nuclear genetic background.
Human molecular genetics 2007;16(3):286-94.
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2007: Xin Zhong-Tao; Beauchamp Adam D; Calado Rodrigo T; Bradford Jennifer W; Regal Joshua A; Shenoy Aarthi; Liang Yuying; Lansdorp Peter M; Young Neal S; Ly Hinh
Functional characterization of natural telomerase mutations found in patients with hematologic disorders.
Blood 2007;109(2):524-32.
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2007: Yao Yong-Gang; Ogasawara Yoji; Kajigaya Sachiko; Molldrem Jeffrey J; Falcão Roberto P; Pintão Maria-Carolina; McCoy J Philip; Rizzatti Edgar Gil; Young Neal S
Mitochondrial DNA sequence variation in single cells from leukemia patients.
Blood 2007;109(2):756-62.
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2007: Yao Yong-Gang; Bandelt Hans-Jürgen; Young Neal S
External contamination in single cell mtDNA analysis.
PloS one 2007;2(1):e681.
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2006: Young Neal S
Hematologic manifestations and diagnosis of parvovirus B19 infections.
Clinical advances in hematology & oncology : H&O 2006;4(12):908-10.
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2006: Young Neal S; Calado Rodrigo T; Scheinberg Phillip
Current concepts in the pathophysiology and treatment of aplastic anemia.
Blood 2006;108(8):2509-19.
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2006: Hillmen Peter; Young Neal S; Schubert Jörg; Brodsky Robert A; Socié Gerard; Muus Petra; Röth Alexander; Szer Jeffrey; Elebute Modupe O; Nakamura Ryotaro; Browne Paul; Risitano Antonio M; Hill Anita; Schrezenmeier Hubert; Fu Chieh-Lin; Maciejewski Jaroslaw; Rollins Scott A; Mojcik Christopher F; Rother Russell P; Luzzatto Lucio
The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.
The New England journal of medicine 2006;355(12):1233-43.
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2006: Sloand Elaine M; Yong Agnes S M; Ramkissoon Shakti; Solomou Elena; Bruno Tullia C; Kim Sonnie; Fuhrer Monika; Kajigaya Sachiko; Barrett A John; Young Neal S
Granulocyte colony-stimulating factor preferentially stimulates proliferation of monosomy 7 cells bearing the isoform IV receptor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(39):14483-8.
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2006: Amexis Georgios; Young Neal S
Parvovirus B19 empty capsids as antigen carriers for presentation of antigenic determinants of dengue 2 virus.
The Journal of infectious diseases 2006;194(6):790-4.
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2006: Scheinberg Phillip; Nunez Olga; Young Neal S
Retreatment with rabbit anti-thymocyte globulin and ciclosporin for patients with relapsed or refractory severe aplastic anaemia.
British journal of haematology 2006;133(6):622-7.
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2006: Scheinberg Phillip; Nunez Olga; Wu Colin; Young Neal S
Treatment of severe aplastic anaemia with combined immunosuppression: anti-thymocyte globulin, ciclosporin and mycophenolate mofetil.
British journal of haematology 2006;133(6):606-11.
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2006: Ogasawara Yoji; Amexis Georgios; Yamaguchi Hiroki; Kajigaya Sachiko; Leppla Stephan H; Young Neal S
Recombinant viral-like particles of parvovirus B19 as antigen carriers of anthrax protective antigen.
In vivo (Athens, Greece) 2006;20(3):319-24.
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2006: Savage Sharon A; Calado Rodrigo T; Xin Zhong-Tao; Ly Hinh; Young Neal S; Chanock Stephen J
Genetic variation in telomeric repeat binding factors 1 and 2 in aplastic anemia.
Experimental hematology 2006;34(5):664-71.
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2006: Srinivasan Ramaprasad; Takahashi Yoshiyuki; McCoy J Philip; Espinoza-Delgado Igor; Dorrance Colleen; Igarashi Takehito; Lundqvist Andreas; Barrett A John; Young Neal S; Geller Nancy; Childs Richard W
Overcoming graft rejection in heavily transfused and allo-immunised patients with bone marrow failure syndromes using fludarabine-based haematopoietic cell transplantation.
British journal of haematology 2006;133(3):305-14.
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2006: Solomou Elena E; Keyvanfar Keyvan; Young Neal S
T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia.
Blood 2006;107(10):3983-91.
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2006: Ramkissoon Shakti H; Mainwaring Lori A; Ogasawara Yoji; Keyvanfar Keyvan; McCoy J Philip; Sloand Elaine M; Kajigaya Sachiko; Young Neal S
Hematopoietic-specific microRNA expression in human cells.
Leukemia research 2006;30(5):643-7.
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2006: Sloand Elaine M; Scheinberg Phillip; Maciejewski Jaroslaw; Young Neal S
Brief communication: Successful treatment of pure red-cell aplasia with an anti-interleukin-2 receptor antibody (daclizumab).
Annals of internal medicine 2006;144(3):181-5.
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2006: Ramkissoon Shakti H; Mainwaring Lori A; Sloand Elaine M; Young Neal S; Kajigaya Sachiko
Nonisotopic detection of microRNA using digoxigenin labeled RNA probes.
Molecular and cellular probes 2006;20(1):1-4.
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2006: Zeng Weihua; Miyazato Akira; Chen Guibin; Kajigaya Sachiko; Young Neal S; Maciejewski Jaroslaw P
Interferon-gamma-induced gene expression in CD34 cells: identification of pathologic cytokine-specific signature profiles.
Blood 2006;107(1):167-75.
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2006: Young Neal S
Pathophysiologic mechanisms in acquired aplastic anemia.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2006;():72-7.
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2005: Ogasawara Yoji; Nakayama Kazutaka; Tarnowka Magdalena; McCoy J Philip; Kajigaya Sachiko; Levin Barbara C; Young Neal S
Mitochondrial DNA spectra of single human CD34+ cells, T cells, B cells, and granulocytes.
Blood 2005;106(9):3271-84.
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2005: Chen Jichun; Brandt Justin S; Ellison Felicia M; Calado Rodrigo T; Young Neal S
Defective stromal cell function in a mouse model of infusion-induced bone marrow failure.
Experimental hematology 2005;33(8):901-8.
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2005: Sloand Elaine M; Mainwaring Lori; Fuhrer Monika; Ramkissoon Shakti; Risitano Antonio M; Keyvanafar Keyvan; Lu Jun; Basu Atanu; Barrett A John; Young Neal S
Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome.
Blood 2005;106(3):841-51.
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2005: Chen G; Zeng W; Maciejewski J P; Kcyvanfar K; Billings E M; Young N S
Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in 'normal' phenotype cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(5):862-8.
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2005: Yamaguchi Hiroki; Calado Rodrigo T; Ly Hinh; Kajigaya Sachiko; Baerlocher Gabriela M; Chanock Stephen J; Lansdorp Peter M; Young Neal S
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia.
The New England journal of medicine 2005;352(14):1413-24.
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2005: Young Neal S
Paroxysmal nocturnal hemoglobinuria: current issues in pathophysiology and treatment.
Current hematology reports 2005;4(2):103-9.
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2005: Ly Hinh; Calado Rodrigo T; Allard Paulette; Baerlocher Gabriela M; Lansdorp Peter M; Young Neal S; Parslow Tristram G
Functional characterization of telomerase RNA variants found in patients with hematologic disorders.
Blood 2005;105(6):2332-9.
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2005: Risitano A M; Maciejewski J P; Muranski P; Wlodarski M; O'Keefe C; Sloand E M; Young N S
Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(2):217-22.
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2004: Bloom Michael L; Wolk Adam G; Simon-Stoos Karen L; Bard Julie S; Chen Jichun; Young Neal S
A mouse model of lymphocyte infusion-induced bone marrow failure.
Experimental hematology 2004;32(12):1163-72.
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2004: Chen Guibin; Zeng Weihua; Miyazato Akira; Billings Eric; Maciejewski Jaroslaw P; Kajigaya Sachiko; Sloand Elaine M; Young Neal S
Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities.
Blood 2004;104(13):4210-8.
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2004: Sloand Elaine M; Mainwaring Lori; Keyvanfar Keyvan; Chen Jichun; Maciejewski Jaroslaw; Klein Harvey G; Young Neal S
Transfer of glycosylphosphatidylinositol-anchored proteins to deficient cells after erythrocyte transfusion in paroxysmal nocturnal hemoglobinuria.
Blood 2004;104(12):3782-8.
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2004: Zeng Weihua; Kajigaya Sachiko; Chen Guibin; Risitano Antonio M; Nunez Olga; Young Neal S
Transcript profile of CD4+ and CD8+ T cells from the bone marrow of acquired aplastic anemia patients.
Experimental hematology 2004;32(9):806-14.
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2004: Chen Jichun; Lipovsky Karen; Ellison Felicia M; Calado Rodrigo T; Young Neal S
Bystander destruction of hematopoietic progenitor and stem cells in a mouse model of infusion-induced bone marrow failure.
Blood 2004;104(6):1671-8.
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2004: Kearns William G; Yamaguchi Hiroki; Young Neal S; Liu Johnson M
Centrosome amplification and aneuploidy in bone marrow failure patients.
Genes, chromosomes & cancer 2004;40(4):329-33.
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2004: Risitano Antonio M; Maciejewski Jaroslaw P; Green Spencer; Plasilova Magdalena; Zeng Weihua; Young Neal S
In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing.
Lancet 2004;364(9431):355-64.
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2004: Kearns William G; Sutton Joanne F; Maciejewski Jaroslaw P; Young Neal S; Liu Johnson M
Genomic instability in bone marrow failure syndromes.
American journal of hematology 2004;76(3):220-4.
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2004: Simak Jan; Holada Karel; Risitano Antonio M; Zivny Jan H; Young Neal S; Vostal Jaroslav G
Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria.
British journal of haematology 2004;125(6):804-13.
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2004: Shin Myung Geun; Kajigaya Sachiko; Tarnowka Magdalena; McCoy J Philip; Levin Barbara C; Young Neal S
Mitochondrial DNA sequence heterogeneity in circulating normal human CD34 cells and granulocytes.
Blood 2004;103(12):4466-77.
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2004: Lu Jun; Basu Atanu; Melenhorst J Joseph; Young Neal S; Brown Kevin E
Analysis of T-cell repertoire in hepatitis-associated aplastic anemia.
Blood 2004;103(12):4588-93.
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2004: Chen Guibin; Zeng Weihua; Green Spencer; Young Neal S
Frequent HPRT mutations in paroxysmal nocturnal haemoglobinuria reflect T cell clonal expansion, not genomic instability.
British journal of haematology 2004;125(3):383-91.
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2004: Plasilova Magdalena; Risitano Antonio M; O'Keefe Christine L; Rodriguez Alexander; Wlodarski Marcin; Young Neal S; Maciejewski Jaroslaw
Shared and individual specificities of immunodominant cytotoxic T-cell clones in paroxysmal nocturnal hemoglobinuria as determined by molecular analysis.
Experimental hematology 2004;32(3):261-9.
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2004: Young Neal S; Brown Kevin E
Parvovirus B19.
The New England journal of medicine 2004;350(6):586-97.
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2004: Sutton Joanne F; Stacey Michael; Kearns William G; Rieg Thomas S; Young Neal S; Liu Johnson M
Increased risk for aplastic anemia and myelodysplastic syndrome in individuals lacking glutathione S-transferase genes.
Pediatric blood & cancer 2004;42(2):122-6.
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2004: O'Keefe Christine L; Plasilova Magdalena; Wlodarski Marcin; Risitano Antonio M; Rodriguez Alexander R; Howe Evan; Young Neal S; Hsi Eric; Maciejewski Jaroslaw P
Molecular analysis of TCR clonotypes in LGL: a clonal model for polyclonal responses.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1960-9.
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2004: Takahashi Yoshiyuki; McCoy J Philip; Carvallo Cristian; Rivera Candido; Igarashi Takehito; Srinivasan Ramaprasad; Young Neal S; Childs Richard W
In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation.
Blood 2004;103(4):1383-90.
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2004: Zeng Weihua; Chen Guibin; Kajigaya Sachiko; Nunez Olga; Charrow Alexandra; Billings Eric M; Young Neal S
Gene expression profiling in CD34 cells to identify differences between aplastic anemia patients and healthy volunteers.
Blood 2004;103(1):325-32.
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2004: Shin Myung Geun; Kajigaya Sachiko; McCoy J Philip; Levin Barbara C; Young Neal S
Marked mitochondrial DNA sequence heterogeneity in single CD34+ cell clones from normal adult bone marrow.
Blood 2004;103(2):553-61.
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2004: Chen Guibin; Kook Hoon; Zeng Weihua; Young Neal S; Maciejewski Jaroslaw P
Is there a direct effect of antithymocyte globulin on hematopoiesis?
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(3):255-61.
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2003: Fogarty Patrick F; Yamaguchi Hiroki; Wiestner Adrian; Baerlocher Gabriela M; Sloand Elaine; Zeng Weihua S; Read Elizabeth J; Lansdorp Peter M; Young Neal S
Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA.
Lancet 2003;362(9396):1628-30.
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2003: Umemura Takeji; Tanaka Eiji; Ostapowicz George; Brown Kevin E; Heringlake Stefan; Tassopoulos Nicolaos C; Wang Richard Y-H; Yeo Anthony E T; Shih J Wai-Kuo; Orii Koji; Young Neal S; Hatzakis Angelos; Manns Michael P; Lee William M; Kiyosawa Kendo; Alter Harvey J
Investigation of SEN virus infection in patients with cryptogenic acute liver failure, hepatitis-associated aplastic anemia, or acute and chronic non-A-E hepatitis.
The Journal of infectious diseases 2003;188(10):1545-52.
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2003: Battiwalla Minoo; Melenhorst Jos; Saunthararajah Yogen; Nakamura Ryotaro; Molldrem Jeffrey; Young Neal S; Barrett A John
HLA-DR4 predicts haematological response to cyclosporine in T-large granular lymphocyte lymphoproliferative disorders.
British journal of haematology 2003;123(3):449-53.
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2003: Sloand E; Childs R W; Solomon S; Greene A; Young N S; Barrett A J
The graft-versus-leukemia effect of nonmyeloablative stem cell allografts may not be sufficient to cure chronic myelogenous leukemia.
Bone marrow transplantation 2003;32(9):897-901.
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2003: Maciejewski Jaroslaw P; Sloand Elaine M; Nunez Olga; Boss Carol; Young Neal S
Recombinant humanized anti-IL-2 receptor antibody (daclizumab) produces responses in patients with moderate aplastic anemia.
Blood 2003;102(10):3584-6.
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2003: Sloand Elaine M; Fuhrer Monika; Keyvanfar Keyvan; Mainwaring Lori; Maciejewski Jaroslaw; Wang Yu; Johnson Sarah; Barrett A John; Young Neal S
Cytogenetic abnormalities in paroxysmal nocturnal haemoglobinuria usually occur in haematopoietic cells that are glycosylphosphatidylinositol-anchored protein (GPI-AP) positive.
British journal of haematology 2003;123(1):173-6.
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2003: Yamaguchi Hiroki; Baerlocher Gabriela M; Lansdorp Peter M; Chanock Stephen J; Nunez Olga; Sloand Elaine; Young Neal S
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome.
Blood 2003;102(3):916-8.
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2003: Yamaguchi Hiroki; Aridgides Laura J; Zeng Weihua; Osgood Christopher; Young Neal S; Liu Johnson M
Genetic and transcriptional analysis of spindle checkpoint genes in bone marrow failure patients.
Blood cells, molecules & diseases 2003;30(3):307-11.
-
2003: Solomon S R; Nakamura R; Read E J; Leitman S F; Carter C; Childs R; Dunbar C E; Young N S; Barrett A J
Cyclosporine is required to prevent severe acute GVHD following T-cell-depleted peripheral blood stem cell transplantation.
Bone marrow transplantation 2003;31(9):783-8.
-
2003: Wong Susan; Young Neal S; Brown Kevin E
Prevalence of parvovirus B19 in liver tissue: no association with fulminant hepatitis or hepatitis-associated aplastic anemia.
The Journal of infectious diseases 2003;187(10):1581-6.
-
2003: Shin Myung Geun; Kajigaya Sachiko; Levin Barbara C; Young Neal S
Mitochondrial DNA mutations in patients with myelodysplastic syndromes.
Blood 2003;101(8):3118-25.
-
2003: Rosenfeld Stephen; Follmann Dean; Nunez Olga; Young Neal S
Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome.
JAMA : the journal of the American Medical Association 2003;289(9):1130-5.
-
2003: Risitano Antonio M; Holada Karel; Chen Guibin; Simak Jan; Vostal Jaroslav G; Young Neal S; Maciejewski Jaroslaw P
CD34+ cells from paroxysmal nocturnal hemoglobinuria (PNH) patients are deficient in surface expression of cellular prion protein (PrPc).
Experimental hematology 2003;31(1):65-72.
-
2002: Zeng Weihua; Maciejewski Jaroslaw P; Chen Guibin; Risitano Antonio M; Kirby Martha; Kajigaya Sachiko; Young Neal S
Selective reduction of natural killer T cells in the bone marrow of aplastic anaemia.
British journal of haematology 2002;119(3):803-9.
-
2002: Sloand Elaine M; Kim Sonnie; Fuhrer Monika; Risitano Antonio M; Nakamura Ryotaro; Maciejewski Jaroslaw P; Barrett A John; Young Neal S
Fas-mediated apoptosis is important in regulating cell replication and death in trisomy 8 hematopoietic cells but not in cells with other cytogenetic abnormalities.
Blood 2002;100(13):4427-32.
-
2002: Tisdale John F; Maciejewski Jaroslaw P; Nuñez Olga; Rosenfeld Stephen J; Young Neal S
Late complications following treatment for severe aplastic anemia (SAA) with high-dose cyclophosphamide (Cy): follow-up of a randomized trial.
Blood 2002;100(13):4668-70.
-
2002: Saunthararajah Yogen; Nakamura Ryotaro; Nam Jun-Mo; Robyn Jamie; Loberiza Fausto; Maciejewski Jaroslaw P; Simonis Toni; Molldrem Jeffrey; Young Neal S; Barrett A John
HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome.
Blood 2002;100(5):1570-4.
-
2002: Young Neal S; Maciejewski Jaroslaw P; Sloand Elaine; Chen Guiben; Zeng Weihua; Risitano Antonio; Miyazato Akira
The relationship of aplastic anemia and PNH.
International journal of hematology 2002;76 Suppl 2():168-72.
-
2002: Maciejewski Jaroslaw P; Risitano Antonio; Kook Hoon; Zeng Weihua; Chen Guibin; Young Neal S
Immune pathophysiology of aplastic anemia.
International journal of hematology 2002;76 Suppl 1():207-14.
-
2002: Molldrem Jeffrey J; Leifer Eric; Bahceci Erkut; Saunthararajah Yogen; Rivera Mary; Dunbar Cynthia; Liu Johnson; Nakamura Riotoro; Young Neal S; Barrett A John
Antithymocyte globulin for treatment of the bone marrow failure associated with myelodysplastic syndromes.
Annals of internal medicine 2002;137(3):156-63.
-
2002: Sloand Elaine; Kim Sonnie; Maciejewski Jaroslaw P; Tisdale John; Follmann Dean; Young Neal S
Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia.
Blood 2002;100(4):1185-91.
-
2002: Nagakura Shoichi; Ishihara Sonoko; Dunn Daniel E; Nishimura Jun-ichi; Kawaguchi Tatsuya; Horikawa Kentaro; Hidaka Michihiro; Kagimoto Tadashi; Eto Nozomu; Mitsuya Hiroaki; Kinoshita Taroh; Young Neal S; Nakakuma Hideki
Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro.
Blood 2002;100(3):1031-7.
-
2002: Chen Guibin; Kirby Martha; Zeng Weihua; Young Neal S; Maciejewski Jaroslaw P
Superior growth of glycophosphatidy linositol-anchored protein-deficient progenitor cells in vitro is due to the higher apoptotic rate of progenitors with normal phenotype in vivo.
Experimental hematology 2002;30(7):774-82.
-
2002: Holada Karel; Simak Jan; Risitano Antonio M; Maciejewski Jaroslaw; Young Neal S; Vostal Jaroslav G
Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein.
Blood 2002;100(1):341-3.
-
2002: Risitano Antonio M; Kook Hoon; Zeng Weihua; Chen Guibin; Young Neal S; Maciejewski Jaroslaw P
Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by V beta CDR3 spectratyping and flow cytometry.
Blood 2002;100(1):178-83.
-
2002: Kook Hoon; Risitano Antonio M; Zeng Weihua; Wlodarski Marcin; Lottemann Craig; Nakamura Ryotaro; Barrett John; Young Neal S; Maciejewski Jaroslaw P
Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens.
Blood 2002;99(10):3668-75.
-
2002: Maciejewski Jaroslaw P; Risitano Antonio; Sloand Elaine M; Nunez Olga; Young Neal S
Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia.
Blood 2002;99(9):3129-35.
-
2002: Young Neal S
Acquired aplastic anemia.
Annals of internal medicine 2002;136(7):534-46.
-
2002: Maciejewski Jaroslaw P; Risitano Antonio M; Sloand Elaine M; Wisch Laura; Geller Nancy; Barrett John A; Young Neal S;
A pilot study of the recombinant soluble human tumour necrosis factor receptor (p75)-Fc fusion protein in patients with myelodysplastic syndrome.
British journal of haematology 2002;117(1):119-26.
-
2002: Young Neal S
Immunosuppressive treatment of acquired aplastic anemia and immune-mediated bone marrow failure syndromes.
International journal of hematology 2002;75(2):129-40.
-
2001: Maciejewski J P; Rivera C; Kook H; Dunn D; Young N S
Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol-anchored protein-deficient clones.
British journal of haematology 2001;115(4):1015-22.
-
2001: Maciejewski J P; Follmann D; Nakamura R; Saunthararajah Y; Rivera C E; Simonis T; Brown K E; Barrett J A; Young N S
Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome.
Blood 2001;98(13):3513-9.
-
2001: Kook H; Zeng W; Guibin C; Kirby M; Young N S; Maciejewski J P
Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia.
Experimental hematology 2001;29(11):1270-7.
-
2001: Nakamura R; Bahceci E; Read E J; Leitman S F; Carter C S; Childs R; Dunbar C E; Gress R; Altemus R; Young N S; Barrett A J
Transplant dose of CD34(+) and CD3(+) cells predicts outcome in patients with haematological malignancies undergoing T cell-depleted peripheral blood stem cell transplants with delayed donor lymphocyte add-back.
British journal of haematology 2001;115(1):95-104.
-
2001: Zeng W; Maciejewski J P; Chen G; Young N S
Limited heterogeneity of T cell receptor BV usage in aplastic anemia.
The Journal of clinical investigation 2001;108(5):765-73.
-
2001: Brümmendorf T H; Maciejewski J P; Mak J; Young N S; Lansdorp P M
Telomere length in leukocyte subpopulations of patients with aplastic anemia.
Blood 2001;97(4):895-900.
-
2001: Saunthararajah Y; Molldrem J L; Rivera M; Williams A; Stetler-Stevenson M; Sorbara L; Young N S; Barrett J A
Coincident myelodysplastic syndrome and T-cell large granular lymphocytic disease: clinical and pathophysiological features.
British journal of haematology 2001;112(1):195-200.
-
2001: Brown K E; Young N S; Alving B M; Barbosa L H
Parvovirus B19: implications for transfusion medicine. Summary of a workshop.
Transfusion 2001;41(1):130-5.
-
2000: Tisdale J F; Dunn D E; Geller N; Plante M; Nunez O; Dunbar C E; Barrett A J; Walsh T J; Rosenfeld S J; Young N S
High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial.
Lancet 2000;356(9241):1554-9.
-
2000: Maciejewski J P; Kim S; Sloand E; Selleri C; Young N S
Sustained long-term hematologic recovery despite a marked quantitative defect in the stem cell compartment of patients with aplastic anemia after immunosuppressive therapy.
American journal of hematology 2000;65(2):123-31.
-
2000: Childs R; Chernoff A; Contentin N; Bahceci E; Schrump D; Leitman S; Read E J; Tisdale J; Dunbar C; Linehan W M; Young N S; Barrett A J
Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation.
The New England journal of medicine 2000;343(11):750-8.
-
2000: Young N S; Maciejewski J P
Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?".
The Journal of clinical investigation 2000;106(5):637-41.
-
2000: Liu Z; Donahue R E; Young N S; Brown K E
Sequencing and characterization of A-2 plaque virus: A new member of the Picornaviridae family.
Virology 2000;272(1):168-76.
-
2000: Sloand E M; Kim S; Maciejewski J P; Van Rhee F; Chaudhuri A; Barrett J; Young N S
Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo.
Blood 2000;95(7):2269-74.
-
2000: Handa A; Jubran R F; Dickstein B; Boylan A; Luban N L; Young N S; Brown K E
GB virus C/Hepatitis G virus infection is frequent in American children and young adults.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30(3):569-71.
-
2000: Bahçeci E; Read E J; Leitman S; Childs R; Dunbar C; Young N S; Barrett A J
CD34+ cell dose predicts relapse and survival after T-cell-depleted HLA-identical haematopoietic stem cell transplantation (HSCT) for haematological malignancies.
British journal of haematology 2000;108(2):408-14.
-
2000: Handa A; Dickstein B; Young N S; Brown K E
Prevalence of the newly described human circovirus, TTV, in United States blood donors.
Transfusion 2000;40(2):245-51.
-
2000: Young N S
Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia.
Seminars in hematology 2000;37(1):3-14.
-
2000: Giri N; Kang E; Tisdale J F; Follman D; Rivera M; Schwartz G N; Kim S; Young N S; Rick M E; Dunbar C E
Clinical and laboratory evidence for a trilineage haematopoietic defect in patients with refractory Diamond-Blackfan anaemia.
British journal of haematology 2000;108(1):167-75.
-
2000: Brown K E; Young N S
Epidemiology and pathology of erythroviruses.
Contributions to microbiology 2000;4():107-22.
-
1999: Childs R; Clave E; Contentin N; Jayasekera D; Hensel N; Leitman S; Read E J; Carter C; Bahceci E; Young N S; Barrett A J
Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses.
Blood 1999;94(9):3234-41.
-
1999: Liu J M; Kim S; Read E J; Futaki M; Dokal I; Carter C S; Leitman S F; Pensiero M; Young N S; Walsh C E
Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC).
Human gene therapy 1999;10(14):2337-46.
-
1999: Dunn D E; Tanawattanacharoen P; Boccuni P; Nagakura S; Green S W; Kirby M R; Kumar M S; Rosenfeld S; Young N S
Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes.
Annals of internal medicine 1999;131(6):401-8.
-
1999: Sloand E M; Kumar P N; Kim S; Chaudhuri A; Weichold F F; Young N S
Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo.
Blood 1999;94(3):1021-7.
-
1999: Young N S
Acquired aplastic anemia.
JAMA : the journal of the American Medical Association 1999;282(3):271-8.
-
1999: Yu J M; Emmons R V; Hanazono Y; Sellers S; Young N S; Dunbar C E
Expression of interferon-gamma by stromal cells inhibits murine long-term repopulating hematopoietic stem cell activity.
Experimental hematology 1999;27(5):895-903.
-
1999: Dunn D E; Ware R E; Parker C J; Mishoe H O; Young N S
Research directions in paroxysmal nocturnal hemoglobinuria.
Immunology today 1999;20(4):168-71.
-
1998: Sloand E M; Maciejewski J P; Dunn D; Moss J; Brewer B; Kirby M; Young N S
Correction of the PNH defect by GPI-anchored protein transfer.
Blood 1998;92(11):4439-45.
-
1998: Sloand E M; Young N S; Sato T; Kim S; Maciejewski J P
Inhibition of interleukin-1beta-converting enzyme in human hematopoietic progenitor cells results in blockade of cytokine-mediated apoptosis and expansion of their proliferative potential.
Experimental hematology 1998;26(11):1093-9.
-
1998: Sato T; Kim S; Selleri C; Young N S; Maciejewski J P
Measurement of secondary colony formation after 5 weeks in long-term cultures in patients with myelodysplastic syndrome.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(8):1187-94.
-
1998: Barrett A J; Mavroudis D; Tisdale J; Molldrem J; Clave E; Dunbar C; Cottler-Fox M; Phang S; Carter C; Okunnieff P; Young N S; Read E J
T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect.
Bone marrow transplantation 1998;21(6):543-51.
-
1998: Weichold F F; Zella D; Barabitskaja O; Maciejewski J P; Dunn D E; Sloand E M; Young N S
Neither human immunodeficiency virus-1 (HIV-1) nor HIV-2 infects most-primitive human hematopoietic stem cells as assessed in long-term bone marrow cultures.
Blood 1998;91(3):907-15.
-
1998: Sloand E M; Maciejewski J P; Sato T; Bruny J; Kumar P; Kim S; Weichold F F; Young N S
The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection.
The Journal of clinical investigation 1998;101(1):195-201.
-
1997: Molldrem J J; Caples M; Mavroudis D; Plante M; Young N S; Barrett A J
Antithymocyte globulin for patients with myelodysplastic syndrome.
British journal of haematology 1997;99(3):699-705.
-
1997: Sato T; Selleri C; Young N S; Maciejewski J P
Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-gamma due to phosphorylation of Stat1 and Stat3.
Blood 1997;90(12):4749-58.
-
1997: Sloand E M; Young N S; Sato T; Kumar P; Kim S; Weichold F F; Maciejewski J P
Secondary colony formation after long-term bone marrow culture using peripheral blood and bone marrow of HIV-infected patients.
AIDS (London, England) 1997;11(13):1547-53.
-
1997: Liu J M; Young N S; Walsh C E; Cottler-Fox M; Carter C; Dunbar C; Barrett A J; Emmons R
Retroviral mediated gene transfer of the Fanconi anemia complementation group C gene to hematopoietic progenitors of group C patients.
Human gene therapy 1997;8(14):1715-30.
-
1997: Abkowitz J L; Brown K E; Wood R W; Kovach N L; Green S W; Young N S
Clinical relevance of parvovirus B19 as a cause of anemia in patients with human immunodeficiency virus infection.
The Journal of infectious diseases 1997;176(1):269-73.
-
1997: O'Sullivan M G; Anderson D K; Goodrich J A; Tulli H; Green S W; Young N S; Brown K E
Experimental infection of cynomolgus monkeys with simian parvovirus.
Journal of virology 1997;71(6):4517-21.
-
1997: Brown K E; Wong S; Young N S
Prevalence of GBV-C/HGV, a novel 'hepatitis' virus, in patients with aplastic anaemia.
British journal of haematology 1997;97(2):492-6.
-
1997: Sato T; Selleri C; Anderson S; Young N S; Maciejewski J P
Expression and modulation of cellular receptors for interferon-gamma, tumour necrosis factor, and Fas on human bone marrow CD34+ cells.
British journal of haematology 1997;97(2):356-65.
-
1997: Young N S; Maciejewski J
The pathophysiology of acquired aplastic anemia.
The New England journal of medicine 1997;336(19):1365-72.
-
1997: Brown K E; Tisdale J; Barrett A J; Dunbar C E; Young N S
Hepatitis-associated aplastic anemia.
The New England journal of medicine 1997;336(15):1059-64.
-
1997: Devetten M P; Liu J M; Ling V; Weichold F F; Yu J; Medof M E; Young N S; Dunn D E
Paroxysmal nocturnal hemoglobinuria: new insights from murine Pig-a-deficient hematopoiesis.
Proceedings of the Association of American Physicians 1997;109(2):99-110.
-
1997: Brown K E; Wong S; Buu M; Binh T V; Be T V; Young N S
High prevalence of GB virus C/hepatitis G virus in healthy persons in Ho Chi Minh City, Vietnam.
The Journal of infectious diseases 1997;175(2):450-3.
-
1997: Sloand E M; Young N S; Kumar P; Weichold F F; Sato T; Maciejewski J P
Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication.
Blood 1997;89(4):1357-63.
-
1997: Maciejewski J P; Sloand E M; Sato T; Anderson S; Young N S
Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone.
Blood 1997;89(4):1173-81.
-
1997: Brown K E; Young N S
Human parvovirus B19 infections in infants and children.
Advances in pediatric infectious diseases 1997;13():101-26.
-
1997: Qazilbash M H; Liu J M; Vlachos A; Fruchtman S; Messner H; Zipursky A; Alter B P; Young N S
A new syndrome of familial aplastic anemia and chronic liver disease.
Acta haematologica 1997;97(3):164-7.
-
1997: Brown K E; Young N S
Parvovirus B19 in human disease.
Annual review of medicine 1997;48():59-67.
-
1996: Maciejewski J P; Young N S; Yu M; Anderson S M; Sloand E M
Analysis of the expression of glycosylphosphatidylinositol anchored proteins on platelets from patients with paroxysmal nocturnal hemoglobinuria.
Thrombosis research 1996;83(6):433-47.
-
1996: Maciejewski J P; Selleri C; Sato T; Anderson S; Young N S
A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia.
Blood 1996;88(6):1983-91.
-
1996: Dunn D E; Yu J; Nagarajan S; Devetten M; Weichold F F; Medof M E; Young N S; Liu J M
A knock-out model of paroxysmal nocturnal hemoglobinuria: Pig-a(-) hematopoiesis is reconstituted following intercellular transfer of GPI-anchored proteins.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7938-43.
-
1996: Muramatsu S; Mizukami H; Young N S; Brown K E
Nucleotide sequencing and generation of an infectious clone of adeno-associated virus 3.
Virology 1996;221(1):208-17.
-
1996: O'Sullivan M G; Anderson D K; Lund J E; Brown W P; Green S W; Young N S; Brown K E
Clinical and epidemiological features of simian parvovirus infection in cynomolgus macaques with severe anemia.
Laboratory animal science 1996;46(3):291-7.
-
1996: Selleri C; Maciejewski J P; Sato T; Young N S
Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition.
Blood 1996;87(10):4149-57.
-
1996: Emmons R V; Reid D M; Cohen R L; Meng G; Young N S; Dunbar C E; Shulman N R
Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction.
Blood 1996;87(10):4068-71.
-
1996: Young N S
Parvovirus infection and its treatment.
Clinical and experimental immunology 1996;104 Suppl 1():26-30.
-
1996: Brown K E; Young N S
Parvoviruses and bone marrow failure.
Stem cells (Dayton, Ohio) 1996;14(2):151-63.
-
1996: Mizukami H; Young N S; Brown K E
Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein.
Virology 1996;217(1):124-30.
-
1996: Young N S
Immune pathophysiology of acquired aplastic anaemia.
European journal of haematology. Supplementum 1996;60():55-9.
-
1996: Young N S
Drug-related blood dyscrasias. Introduction.
European journal of haematology. Supplementum 1996;60():6-8.
-
1995: Sato T; Selleri C; Young N S; Maciejewski J P
Hematopoietic inhibition by interferon-gamma is partially mediated through interferon regulatory factor-1.
Blood 1995;86(9):3373-80.
-
1995: Kawase M; Momoeda M; Young N S; Kajigaya S
Modest truncation of the major capsid protein abrogates B19 parvovirus capsid formation.
Journal of virology 1995;69(10):6567-71.
-
1995: Brown K E; Young N S
Parvovirus B19 infection and hematopoiesis.
Blood reviews 1995;9(3):176-82.
-
1995: Maciejewski J P; Selleri C; Sato T; Anderson S; Young N S
Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia.
British journal of haematology 1995;91(1):245-52.
-
1995: Kawase M; Momoeda M; Young N S; Kajigaya S
Most of the VP1 unique region of B19 parvovirus is on the capsid surface.
Virology 1995;211(2):359-66.
-
1995: Maciejewski J P; Selleri C; Sato T; Cho H J; Keefer L K; Nathan C F; Young N S
Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha.
The Journal of clinical investigation 1995;96(2):1085-92.
-
1995: Brown K E; Green S W; O'Sullivan M G; Young N S
Cloning and sequencing of the simian parvovirus genome.
Virology 1995;210(2):314-22.
-
1995: Brown K E; Green S W; Young N S
Goose parvovirus--an autonomous member of the dependovirus genus?
Virology 1995;210(2):283-91.
-
1995: Young N S
Aplastic anaemia.
Lancet 1995;346(8969):228-32.
-
1995: Maciejewski J P; Weichold F F; Young N S; Cara A; Zella D; Reitz M S; Gallo R C
Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro.
Nature medicine 1995;1(7):667-73.
-
1995: Young N S; Barrett A J
The treatment of severe acquired aplastic anemia.
Blood 1995;85(12):3367-77.
-
1995: Rosenfeld S J; Kimball J; Vining D; Young N S
Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia.
Blood 1995;85(11):3058-65.
-
1995: Gallinella G; Anderson S M; Young N S; Brown K E
Human parvovirus B19 can infect cynomolgus monkey marrow cells in tissue culture.
Journal of virology 1995;69(6):3897-9.
-
1995: Maciejewski J; Selleri C; Anderson S; Young N S
Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro.
Blood 1995;85(11):3183-90.
-
1995: Momoeda M; Kawase M; Young N S; Kajigaya S
Purification of functional recombinant YY1 expressed in Sf9 insect cells.
Protein expression and purification 1995;6(2):169-75.
-
1995: Anderson S; Momoeda M; Kawase M; Kajigaya S; Young N S
Peptides derived from the unique region of B19 parvovirus minor capsid protein elicit neutralizing antibodies in rabbits.
Virology 1995;206(1):626-32.
-
1994: Liu J M; Buchwald M; Walsh C E; Young N S
Fanconi anemia and novel strategies for therapy.
Blood 1994;84(12):3995-4007.
-
1994: Momoeda M; Wong S; Kawase M; Young N S; Kajigaya S
A putative nucleoside triphosphate-binding domain in the nonstructural protein of B19 parvovirus is required for cytotoxicity.
Journal of virology 1994;68(12):8443-6.
-
1994: Hartman K R; Brown K E; Green S W; Young N S
Lack of evidence for parvovirus B19 viraemia in children with chronic neutropenia.
British journal of haematology 1994;88(4):895-6.
-
1994: Gallinella G; Young N S; Brown K E
In situ hybridisation and in situ polymerase chain reaction detection of parvovirus B19 DNA within cells.
Journal of virological methods 1994;50(1-3):67-74.
-
1994: Momoeda M; Kawase M; Jane S M; Miyamura K; Young N S; Kajigaya S
The transcriptional regulator YY1 binds to the 5'-terminal region of B19 parvovirus and regulates P6 promoter activity.
Journal of virology 1994;68(11):7159-68.
-
1994: Maciejewski J P; Weichold F F; Young N S
HIV-1 suppression of hematopoiesis in vitro mediated by envelope glycoprotein and TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):4303-10.
-
1994: Walsh C E; Nienhuis A W; Samulski R J; Brown M G; Miller J L; Young N S; Liu J M
Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector.
The Journal of clinical investigation 1994;94(4):1440-8.
-
1994: Maciejewski J P; Hibbs J R; Anderson S; Katevas P; Young N S
Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure.
Experimental hematology 1994;22(11):1102-10.
-
1994: Miller J L; Donahue R E; Sellers S E; Samulski R J; Young N S; Nienhuis A W
Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):10183-7.
-
1994: Goodman S; Xiao X; Donahue R E; Moulton A; Miller J; Walsh C; Young N S; Samulski R J; Nienhuis A W
Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells.
Blood 1994;84(5):1492-500.
-
1994: Miyamura K; Kajigaya S; Momoeda M; Smith-Gill S J; Young N S
Parvovirus particles as platforms for protein presentation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8507-11.
-
1994: Brodsky R A; Hasegawa S; Fibach E; Dunbar C E; Young N S; Rodgers G P
Acquired sideroblastic anaemia following progesterone therapy.
British journal of haematology 1994;87(4):859-62.
-
1994: Wong S; Momoeda M; Field A; Kajigaya S; Young N S
Formation of empty B19 parvovirus capsids by the truncated minor capsid protein.
Journal of virology 1994;68(7):4690-4.
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1994: Walsh C E; Grompe M; Vanin E; Buchwald M; Young N S; Nienhuis A W; Liu J M
A functionally active retrovirus vector for gene therapy in Fanconi anemia group C.
Blood 1994;84(2):453-9.
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1994: Maciejewski J P; Anderson S; Katevas P; Young N S
Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure.
British journal of haematology 1994;87(2):227-34.
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1994: O'Sullivan M G; Anderson D C; Fikes J D; Bain F T; Carlson C S; Green S W; Young N S; Brown K E
Identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia. A paradigm of human B19 parvovirus infection.
The Journal of clinical investigation 1994;93(4):1571-6.
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1994: Brown K E; Hibbs J R; Gallinella G; Anderson S M; Lehman E D; McCarthy P; Young N S
Resistance to parvovirus B19 infection due to lack of virus receptor (erythrocyte P antigen).
The New England journal of medicine 1994;330(17):1192-6.
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1994: Brown K E; Green S W; Antunez de Mayolo J; Bellanti J A; Smith S D; Smith T J; Young N S
Congenital anaemia after transplacental B19 parvovirus infection.
Lancet 1994;343(8902):895-6.
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1994: Nisticò A; Young N S
gamma-Interferon gene expression in the bone marrow of patients with aplastic anemia.
Annals of internal medicine 1994;120(6):463-9.
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1994: Young N S
Agranulocytosis.
JAMA : the journal of the American Medical Association 1994;271(12):935-8.
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1994: Brown K E; Young N S; Liu J M
Molecular, cellular and clinical aspects of parvovirus B19 infection.
Critical reviews in oncology/hematology 1994;16(1):1-31.
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1994: Rosenfeld S J; Young N S; Alling D; Ayub J; Saxinger C
Subunit interaction in B19 parvovirus empty capsids.
Archives of virology 1994;136(1-2):9-18.
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1993: Liu J M; Auerbach A D; Anderson S M; Green S W; Young N S
A trial of recombinant human superoxide dismutase in patients with Fanconi anaemia.
British journal of haematology 1993;85(2):406-8.
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1993: Brown K E; Anderson S M; Young N S
Erythrocyte P antigen: cellular receptor for B19 parvovirus.
Science (New York, N.Y.) 1993;262(5130):114-7.
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1993: Maciejewski J P; Bruening E E; Donahue R E; Sellers S E; Carter C; Young N S; St Jeor S
Infection of mononucleated phagocytes with human cytomegalovirus.
Virology 1993;195(2):327-36.
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1993: Saikawa T; Anderson S; Momoeda M; Kajigaya S; Young N S
Neutralizing linear epitopes of B19 parvovirus cluster in the VP1 unique and VP1-VP2 junction regions.
Journal of virology 1993;67(6):3004-9.
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1993: Bansal G P; Hatfield J A; Dunn F E; Kramer A A; Brady F; Riggin C H; Collett M S; Yoshimoto K; Kajigaya S; Young N S
Candidate recombinant vaccine for human B19 parvovirus.
The Journal of infectious diseases 1993;167(5):1034-44.
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1993: Shimomura S; Wong S; Brown K E; Komatsu N; Kajigaya S; Young N S
Early and late gene expression in UT-7 cells infected with B19 parvovirus.
Virology 1993;194(1):149-56.
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1992: Maciejewski J P; Liu J M; Green S W; Walsh C E; Plumb M; Pragnell I B; Young N S
Expression of stem cell inhibitor (SCI) gene in patients with bone marrow failure.
Experimental hematology 1992;20(9):1112-7.
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1992: Liu J M; Green S W; Shimada T; Young N S
A block in full-length transcript maturation in cells nonpermissive for B19 parvovirus.
Journal of virology 1992;66(8):4686-92.
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1992: Walsh C E; Liu J M; Xiao X; Young N S; Nienhuis A W; Samulski R J
Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7257-61.
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1992: Maciejewski J P; Bruening E E; Donahue R E; Mocarski E S; Young N S; St Jeor S C
Infection of hematopoietic progenitor cells by human cytomegalovirus.
Blood 1992;80(1):170-8.
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1992: Koziol D E; Kurtzman G; Ayub J; Young N S; Henderson D K
Nosocomial human parvovirus B19 infection: lack of transmission from a chronically infected patient to hospital staff.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 1992;13(6):343-8.
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1992: Rosenfeld S J; Yoshimoto K; Kajigaya S; Anderson S; Young N S; Field A; Warrener P; Bansal G; Collett M S
Unique region of the minor capsid protein of human parvovirus B19 is exposed on the virion surface.
The Journal of clinical investigation 1992;89(6):2023-9.
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1992: Hibbs J R; Issaragrisil S; Young N S
High prevalence of hepatitis C viremia among aplastic anemia patients and controls from Thailand.
The American journal of tropical medicine and hygiene 1992;46(5):564-70.
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1992: Hibbs J R; Frickhofen N; Rosenfeld S J; Feinstone S M; Kojima S; Bacigalupo A; Locasciulli A; Tzakis A G; Alter H J; Young N S
Aplastic anemia and viral hepatitis. Non-A, Non-B, Non-C?
JAMA : the journal of the American Medical Association 1992;267(15):2051-4.
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1992: Young N S
The problem of clonality in aplastic anemia: Dr Dameshek's riddle, restated.
Blood 1992;79(6):1385-92.
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1992: Shimomura S; Komatsu N; Frickhofen N; Anderson S; Kajigaya S; Young N S
First continuous propagation of B19 parvovirus in a cell line.
Blood 1992;79(1):18-24.
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1992: Walsh C E; Liu J M; Anderson S M; Rossio J L; Nienhuis A W; Young N S
A trial of recombinant human interleukin-1 in patients with severe refractory aplastic anaemia.
British journal of haematology 1992;80(1):106-10.
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1991: Yoshimoto K; Rosenfeld S; Frickhofen N; Kennedy D; Hills R; Kajigaya S; Young N S
A second neutralizing epitope of B19 parvovirus implicates the spike region in the immune response.
Journal of virology 1991;65(12):7056-60.
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1991: Liu J M; Green S W; Hao Y S; McDonagh K T; Young N S; Shimada T
Upstream sequences within the terminal hairpin positively regulate the P6 promoter of B19 parvovirus.
Virology 1991;185(1):39-47.
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1991: Frickhofen N; Young N S
A rapid method of sample preparation for detection of DNA viruses in human serum by polymerase chain reaction.
Journal of virological methods 1991;35(1):65-72.
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1991: Dunbar C E; Smith D A; Kimball J; Garrison L; Nienhuis A W; Young N S
Treatment of Diamond-Blackfan anaemia with haematopoietic growth factors, granulocyte-macrophage colony stimulating factor and interleukin 3: sustained remissions following IL-3.
British journal of haematology 1991;79(2):316-21.
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1991: Kajigaya S; Fujii H; Field A; Anderson S; Rosenfeld S; Anderson L J; Shimada T; Young N S
Self-assembled B19 parvovirus capsids, produced in a baculovirus system, are antigenically and immunogenically similar to native virions.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4646-50.
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1991: Rosenfeld S J; Young N S
Viruses and bone marrow failure.
Blood reviews 1991;5(2):71-7.
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1991: Liu J M; Fujii H; Green S W; Komatsu N; Young N S; Shimada T
Indiscriminate activity from the B19 parvovirus p6 promoter in nonpermissive cells.
Virology 1991;182(1):361-4.
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1991: Young N S; Rosenfeld S; Antunez-de-Mayolo J; Hibbs J; Liu J; Maciejewski J; St Jeor S; Shimomura S; Kajigaya S
Viruses and bone marrow failure.
Schweizerische medizinische Wochenschrift. Supplementum 1991;43():28-32.
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1990: Frickhofen N; Young N S
Polymerase chain reaction for detection of parvovirus B19 in immunodeficient patients with anemia.
Behring Institute Mitteilungen 1990;(85):46-54.
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1990: Young N S
Flaviviruses and bone marrow failure.
JAMA : the journal of the American Medical Association 1990;263(22):3065-8.
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1990: Frickhofen N; Liu J M; Young N S
Etiologic mechanisms of hematopoietic failure.
The American journal of pediatric hematology/oncology 1990;12(4):385-95.
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1989: Frickhofen N; Young N S
Persistent parvovirus B19 infections in humans.
Microbial pathogenesis 1989;7(5):319-27.
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1989: Kajigaya S; Shimada T; Fujita S; Young N S
A genetically engineered cell line that produces empty capsids of B19 (human) parvovirus.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7601-5.
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1989: Kurtzman G J; Cohen B J; Field A M; Oseas R; Blaese R M; Young N S
Immune response to B19 parvovirus and an antibody defect in persistent viral infection.
The Journal of clinical investigation 1989;84(4):1114-23.
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1989: Nakao S; Lai C J; Young N S
Dengue virus, a flavivirus, propagates in human bone marrow progenitors and hematopoietic cell lines.
Blood 1989;74(4):1235-40.
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1989: Kurtzman G; Frickhofen N; Kimball J; Jenkins D W; Nienhuis A W; Young N S
Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy.
The New England journal of medicine 1989;321(8):519-23.
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1989: Kurtzman G J; Platanias L; Lustig L; Frickhofen N; Young N S
Feline parvovirus propagates in cat bone marrow cultures and inhibits hematopoietic colony formation in vitro.
Blood 1989;74(1):71-81.
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1989: Leonard E M; Raefsky E; Griffith P; Kimball J; Nienhuis A W; Young N S
Cyclosporine therapy of aplastic anaemia, congenital and acquired red cell aplasia.
British journal of haematology 1989;72(2):278-84.
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1989: Young N S; Baranski B; Kurtzman G
The immune system as mediator of virus-associated bone marrow failure: B19 parvovirus and Epstein-Barr virus.
Annals of the New York Academy of Sciences 1989;554():75-80.
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1988: Kurtzman G J; Cohen B; Meyers P; Amunullah A; Young N S
Persistent B19 parvovirus infection as a cause of severe chronic anaemia in children with acute lymphocytic leukaemia.
Lancet 1988;2(8621):1159-62.
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1988: Baranski B; Armstrong G; Truman J T; Quinnan G V; Straus S E; Young N S
Epstein-Barr virus in the bone marrow of patients with aplastic anemia.
Annals of internal medicine 1988;109(9):695-704.
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1988: Kurtzman G J; Gascon P; Caras M; Cohen B; Young N S
B19 parvovirus replicates in circulating cells of acutely infected patients.
Blood 1988;71(5):1448-54.
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1988: Bielory L; Gascon P; Lawley T J; Young N S; Frank M M
Human serum sickness: a prospective analysis of 35 patients treated with equine anti-thymocyte globulin for bone marrow failure.
Medicine 1988;67(1):40-57.
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1988: Baranski B G; Young N S
Autoimmune aspects of aplastic anemia.
In vivo (Athens, Greece) 1988;2(1):91-4.
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1987: Kurtzman G J; Ozawa K; Cohen B; Hanson G; Oseas R; Young N S
Chronic bone marrow failure due to persistent B19 parvovirus infection.
The New England journal of medicine 1987;317(5):287-94.
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1987: Young N S; Leonard E; Platanias L
Lymphocytes and lymphokines in aplastic anemia: pathogenic role and implications for pathogenesis.
Blood cells 1987;13(1-2):87-100.
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1986: Bielory L; Gascon P; Lawley T J; Nienhuis A; Frank M M; Young N S
Serum sickness and haematopoietic recovery with antithymocyte globulin in bone marrow failure patients.
British journal of haematology 1986;63(4):729-36.
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1985: Lawley T J; Bielory L; Gascon P; Yancey K B; Young N S; Frank M M
A study of human serum sickness.
The Journal of investigative dermatology 1985;85(1 Suppl):129s-132s.
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1985: Gascon P; Zoumbos N C; Scala G; Djeu J Y; Moore J G; Young N S
Lymphokine abnormalities in aplastic anemia: implications for the mechanism of action of antithymocyte globulin.
Blood 1985;65(2):407-13.
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1985: Zoumbos N C; Gascon P; Djeu J Y; Young N S
Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(1):188-92.
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1984: Lawley T J; Bielory L; Gascon P; Yancey K B; Young N S; Frank M M
A prospective clinical and immunologic analysis of patients with serum sickness.
The New England journal of medicine 1984;311(22):1407-13.
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1984: Lawley T J; Bielory L; Gascon P; Yancey K B; Young N S; Frank M M
Human serum sickness.
Transactions of the Association of American Physicians 1984;97():49-55.
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1982: Vembu D; Young N S; Willing M; Church E; Sanders-Haigh L; Anderson W F
Regulation of human globin gene expression in mouse erythroleukemia x human fibroblast hybrid cells.
Somatic cell genetics 1982;8(2):163-78.
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