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William Young

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Yoannis Imbert-Fernandez; Brandie N Radde; Yun Teng; William W Young; Chuan Hu; Carolyn M Klinge
MUC1/A and MUC1/B splice variants differentially regulate inflammatory cytokine expression.
Yoannis Imbert; Gary N Foulks; Mark D Brennan; Marcia M Jumblatt; George John; Hassan A Shah; Catherine Newton; Farzan Pouranfar; William W Young
MUC1 and estrogen receptor alpha gene polymorphisms in dry eye patients.
Yoannis Imbert; Marcia M Jumblatt; Gary N Foulks; Erica G Couzin; Pamela S Steele; William W Young
Expression in human ocular surface tissues of the GalNAc-transferases that initiate mucin-type O-glycosylation.

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2011: Yoannis Imbert-Fernandez; Brandie N Radde; Yun Teng; William W Young; Chuan Hu; Carolyn M Klinge
MUC1/A and MUC1/B splice variants differentially regulate inflammatory cytokine expression.
Experimental eye research 2011;93(5):649-57.
2009: Yoannis Imbert; Gary N Foulks; Mark D Brennan; Marcia M Jumblatt; George John; Hassan A Shah; Catherine Newton; Farzan Pouranfar; William W Young
MUC1 and estrogen receptor alpha gene polymorphisms in dry eye patients.
Experimental eye research 2009;88(3):334-8.
2006: Yoannis Imbert; Marcia M Jumblatt; Gary N Foulks; Erica G Couzin; Pamela S Steele; William W Young
Expression in human ocular surface tissues of the GalNAc-transferases that initiate mucin-type O-glycosylation.
Cornea 2006;25(10):1193-9.
2006: Yoannis Imbert; Douglas Darling; Marcia M Jumblatt; Gary N Foulks; Erica G Couzin; Pamela S Steele; William W Young
MUC1 splice variants in human ocular surface tissues: possible differences between dry eye patients and normal controls.
Experimental eye research 2006;83(3):493-501.
2006: Marcia M Jumblatt; Yoannis Imbert; William W Young; Gary N Foulks; Pamela S Steele; Donald R Demuth
Glycoprotein 340 in normal human ocular surface tissues and tear film.
Infection and immunity 2006;74(7):4058-63.
2005: Yuqiang Wei; Ten-Yang Yen; Jian Cai; John O Trent; William M Pierce; William W Young
Structural features of the lysosomal hydrolase mannose 6-phosphate uncovering enzyme.
Glycoconjugate journal 2005;22(1-2):13-9.
2004: Partha Mukhopadhyay; Robert Greene; Wolfgang Zacharias; Martin C Weinrich; Saurabh Singh; William W Young; M Michele Pisano
Developmental gene expression profiling of mammalian, fetal orofacial tissue.
Birth defects research. Part A, Clinical and molecular teratology 2004;70(12):912-26.
2004: E Tian; Kelly G Ten Hagen; Lillian Shum; Howard C Hang; Yoannis Imbert; William W Young; Carolyn R Bertozzi; Lawrence Tabak
An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues.
The Journal of biological chemistry 2004;279(48):50382-90.
2004: William W Young
Organization of Golgi glycosyltransferases in membranes: complexity via complexes.
The Journal of membrane biology 2004;198(1):1-13.
2003: William W Young; Dana R Holcomb; Kelly G Ten Hagen; Lawrence Tabak
Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase isoforms in murine tissues determined by real-time PCR: a new view of a large family.
Glycobiology 2003;13(7):549-57.
2001: Jianghong Li; David M Rancour; ML Allende; CA Worth; Douglas Darling; J B Gilbert; Anant K Menon; William W Young
The DXD motif is required for GM2 synthase activity but is not critical for nucleotide binding.
Glycobiology 2001;11(3):217-29.
2000: Jianghong Li; Ten-Yang Yen; ML Allende; RK Joshi; Jian Cai; William M Pierce; E Jaskiewicz; Douglas Darling; Bruce A Macher; William W Young
Disulfide bonds of GM2 synthase homodimers. Antiparallel orientation of the catalytic domains.
The Journal of biological chemistry 2000;275(52):41476-86.
2000: ML Allende; Jianghong Li; Douglas Darling; CA Worth; William W Young
Evidence supporting a late Golgi location for lactosylceramide to ganglioside GM3 conversion.
Glycobiology 2000;10(10):1025-32.
1999: William W Young; ML Allende; E Jaskiewicz
Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA.
Glycobiology 1999;9(7):689-95.
1998: G Zhu; ML Allende; E Jaskiewicz; R Qian; Douglas Darling; CA Worth; Karen J Colley; William W Young
Two soluble glycosyltransferases glycosylate less efficiently in vivo than their membrane bound counterparts.
Glycobiology 1998;8(8):831-40.
1997: ML Allende; R M Schwendiman; William W Young
Appearance of beta 1,4 N-acetylgalactosaminyltransferase (glycosphingolipids GA2/GM2/GD2 synthase) in embryonic chicken vitreous humor during development.
Current eye research 1997;16(12):1263-9.
1997: G Zhu; E Jaskiewicz; R Bassi; Douglas Darling; William W Young
Beta 1,4 N-acetylgalactosaminyltransferase (GM2/GD2/GA2 synthase) forms homodimers in the endoplasmic reticulum: a strategy to test for dimerization of Golgi membrane proteins.
Glycobiology 1997;7(7):987-96.
1996: E Jaskiewicz; G Zhu; R Bassi; Douglas Darling; William W Young
Beta1,4-N-acetylgalactosaminyltransferase (GM2 synthase) is released from Golgi membranes as a neuraminidase-sensitive, disulfide-bonded dimer by a cathepsin D-like protease.
The Journal of biological chemistry 1996;271(42):26395-403.
1996: E Jaskiewicz; G Zhu; D J Taatjes; Douglas Darling; G E Zwanzig; William W Young
Cloned beta 1,4N-acetylgalactosaminyltransferase: subcellular localization and formation of disulfide bonded species.
Glycoconjugate journal 1996;13(2):213-23.
1994: M S Lutz; E Jaskiewicz; Douglas Darling; K Furukawa; William W Young
Cloned beta 1,4 N-acetylgalactosaminyltransferase synthesizes GA2 as well as gangliosides GM2 and GD2. GM3 synthesis has priority over GA2 synthesis for utilization of lactosylceramide substrate in vivo.
The Journal of biological chemistry 1994;269(46):29227-31.
1994: Dale Warnock; M S Lutz; W A Blackburn; William W Young; Jacques U Baenziger
Transport of newly synthesized glucosylceramide to the plasma membrane by a non-Golgi pathway.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2708-12.
1993: Dale Warnock; C Roberts; M S Lutz; W A Blackburn; William W Young; Jacques U Baenziger
Determination of plasma membrane lipid mass and composition in cultured Chinese hamster ovary cells using high gradient magnetic affinity chromatography.
The Journal of biological chemistry 1993;268(14):10145-53.
1993: William W Young
Molecular approaches to studying the intracellular trafficking of glycosphingolipids.
Advances in lipid research 1993;26():161-79.
1992: William W Young; M S Lutz; W A Blackburn
Endogenous glycosphingolipids move to the cell surface at a rate consistent with bulk flow estimates.
The Journal of biological chemistry 1992;267(17):12011-5.
1991: P Rock; M Allietta; William W Young; TE Thompson; T W Tillack
Ganglioside GM1 and asialo-GM1 at low concentration are preferentially incorporated into the gel phase in two-component, two-phase phosphatidylcholine bilayers.
Biochemistry 1991;30(1):19-25.
1990: P Rock; M Allietta; William W Young; TE Thompson; T W Tillack
Organization of glycosphingolipids in phosphatidylcholine bilayers: use of antibody molecules and Fab fragments as morphologic markers.
Biochemistry 1990;29(36):8484-90.
1990: William W Young; M S Lutz; S E Mills; S Lechler-Osborn
Use of brefeldin A to define sites of glycosphingolipid synthesis: GA2/GM2/GD2 synthase is trans to the brefeldin A block.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6838-42.
1989: V M Gordon; William W Young; S M Lechler; Mary C Gray; Stephen H Leppla; Erik L Hewlett
Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells.
The Journal of biological chemistry 1989;264(25):14792-6.
1988: G E Nichols; T Shiraishi; William W Young
Polarity of neutral glycolipids, gangliosides, and sulfated lipids in MDCK epithelial cells.
Journal of lipid research 1988;29(9):1205-13.
1988: T Shiraishi; Michael Kinter; S E Mills; M C Lippert; G Steven Bova; William W Young
The glycosphingolipids of human prostate tissue.
Biochimica et biophysica acta 1988;961(2):160-9.
1988: William W Young; S E Mills; M C Lippert; P Ahmed; S K Lau
Deletion of antigens of the Lewis a/b blood group family in human prostatic carcinoma.
The American journal of pathology 1988;131(3):578-86.
1987: J Vitali; William W Young; V B Schatz; S E Sobottka; Robert H Kretsinger
Crystal structure of an anti-Lewis alpha Fab determined by molecular replacement methods.
Journal of molecular biology 1987;198(2):351-5.
1987: G E Nichols; T Shiraishi; M Allietta; T W Tillack; William W Young
Polarity of the Forssman glycolipid in MDCK epithelial cells.
Biochimica et biophysica acta 1987;930(2):154-66.
1987: William W Young; C A Borgman
Short-bed, continuous development, thin-layer chromatography of glycosphingolipids.
Methods in enzymology 1987;138():125-32.
1986: G E Nichols; C A Borgman; William W Young
On tight junction structure: Forssman glycolipid does not flow between MDCK cells in an intact epithelial monolayer.
Biochemical and biophysical research communications 1986;138(3):1163-9.
1986: G E Nichols; J C Lovejoy; C A Borgman; J M Sanders; William W Young
Isolation and characterization of two types of MDCK epithelial cell clones based on glycosphingolipid pattern.
Biochimica et biophysica acta 1986;887(1):1-12.
1986: William W Young; C A Borgman; D M Wolock
Modes of shedding of glycosphingolipids from mouse lymphoma cells.
The Journal of biological chemistry 1986;261(5):2279-83.
1986: William W Young; C A Borgman
Short bed-continuous development thin-layer chromatography of glycosphingolipids.
Journal of lipid research 1986;27(1):120-4.
1984: William W Young; Y Tamura; D M Wolock; J W Fox
Staphylococcal protein A binding to the Fab fragments of mouse monoclonal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1984;133(6):3163-6.
1983: T W Tillack; M Allietta; R E Moran; William W Young
Localization of globoside and Forssman glycolipids on erythrocyte membranes.
Biochimica et biophysica acta 1983;733(1):15-24.