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Koichi Akashi

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Robert S Welner; Min Ye; Hong Zhang; K Disnika Senali Abayratna Wansa; Koichi Akashi; Giovanni Amabile; Christian Bach; Deepak Bararia; Touati Benoukraf; Akos Czibere; Christopher J Hetherington; Tadafumi Iino; Daniel G Tenen
C/EBPα is required for development of dendritic cell progenitors.
Naoyasu Ueda; Koichi Akashi; Yojiro Arinobu; Masahiro Ayano; Yasushi Inoue; Hiroki Mitoma; Hiroaki Niiro; Shun-Ichiro Ohta; Atsushi Tanaka; Hiroshi Tsukamoto; Takahiko Horiuchi
The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α.
Koji Kato; Takuro Kuriyama; Toshihiro Miyamoto; Yasuo Mori; Tsuyoshi Muta; Takashi Nakaike; Akihiko Numata; Hideyo Oka; Katsuto Takenaka; Takanori Teshima; Satoshi Yamasaki; Ayano Yurino; Hiromi Iwasaki; Koichi Akashi
Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia/lymphoma.

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2013: Robert S Welner; Min Ye; Hong Zhang; K Disnika Senali Abayratna Wansa; Koichi Akashi; Giovanni Amabile; Christian Bach; Deepak Bararia; Touati Benoukraf; Akos Czibere; Christopher J Hetherington; Tadafumi Iino; Daniel G Tenen
C/EBPα is required for development of dendritic cell progenitors.
Blood 2013;121(20):4073-81.
2013: Naoyasu Ueda; Koichi Akashi; Yojiro Arinobu; Masahiro Ayano; Yasushi Inoue; Hiroki Mitoma; Hiroaki Niiro; Shun-Ichiro Ohta; Atsushi Tanaka; Hiroshi Tsukamoto; Takahiko Horiuchi
The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α.
Inflammatory bowel diseases 2013;19(6):1224-31.
2013: Koji Kato; Takuro Kuriyama; Toshihiro Miyamoto; Yasuo Mori; Tsuyoshi Muta; Takashi Nakaike; Akihiko Numata; Hideyo Oka; Katsuto Takenaka; Takanori Teshima; Satoshi Yamasaki; Ayano Yurino; Hiromi Iwasaki; Koichi Akashi
Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia/lymphoma.
International journal of hematology 2013;97(3):430-2.
2013: Takuji Yamauchi; Nakayuki Honma; Chika Iwamoto; Hiromi Iwasaki; Yoshikane Kikushige; Takashi Matozaki; Toshihiro Miyamoto; Miki Nakao; Mariko Nishihara; Takahiro Shima; Katsuto Takenaka; Takahito Tokuyama; Shingo Urata; Koichi Akashi
Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.
Blood 2013;121(8):1316-25.
2013: Tomohiko Kamimura; Toshihiro Miyamoto; Shuichiro Takashima; Noriko Yokota; Yong Chong; Yoshikiyo Ito; Koichi Akashi
Higher incidence of injection site reactions after subcutaneous bortezomib administration on the thigh compared with the abdomen.
European journal of haematology 2013;90(2):157-61.
2013: Masahiko Fujihara; Mitsuhiro Fukata; Toru Maruyama; Keita Odashiro; Koichi Akashi; Yoshiaki Yokoi
Reduced plasma eicosapentaenoic acid-arachidonic acid ratio in peripheral artery disease.
Angiology 2013;64(2):112-8.
2013: Takahiro Shima; Ken Takase; Katsuto Takenaka; Takanori Teshima; Tetsuya Eto; Hideho Henzan; Yoshikiyo Ito; Hiromi Iwasaki; Kenjirou Kamezaki; Tomohiko Kamimura; Koji Kato; Yoshikane Kikushige; Toshihiro Miyamoto; Yasuo Mori; Koji Nagafuji; Akihiko Numata; Koichi Akashi
Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation.
Blood 2013;121(5):840-8.
2013: Kazumitsu Maehara; Koji Nagao; Chikashi Obuse; Jun Odawara; Koichi Akashi; Akihito Harada; Toshio Sakata; Taro Tachibana; Tomohiko Yoshimi; Yasuyuki Ohkawa
A co-localization model of paired ChIP-seq data using a large ENCODE data set enables comparison of multiple samples.
Nucleic acids research 2013;41(1):54-62.
2013: Mitsuhiro Fukata; Mine Harada; Fumihiko Ishikawa; Takaaki Kanemaru; Kohta Miyawaki; Koji Nagafuji; Yuho Najima; Kei-Ichiro Nakamura; Keita Odashiro; Yoriko Saito; Hideki Shimazu; Kazuya Shimoda; Katsuto Takenaka; Takuji Yamauchi; Koichi Akashi
Contribution of bone marrow-derived hematopoietic stem/progenitor cells to the generation of donor-marker(+) cardiomyocytes in vivo.
PloS one 2013;8(5):e62506.
2013: Yong Chong; Yoshikiyo Ito; Tomohiko Kamimura; Toshihiro Miyamoto; Shinji Shimoda; Nobuyuki Shimono; Hiroko Yakushiji; Koichi Akashi
Antibiotic rotation for febrile neutropenic patients with hematological malignancies: clinical significance of antibiotic heterogeneity.
PloS one 2013;8(1):e54190.
2013: Hitoshi Kusaba; Kenji Mitsugi; Keita Uchino; Koichi Akashi; Shuji Arita; Taito Esaki; Junji Kishimoto; Hozumi Kumagai; Eishi Baba
Phase I study of bevacizumab combined with irinotecan and S-1 as second-line chemotherapy in patients with advanced colorectal cancer.
Cancer chemotherapy and pharmacology 2013;71(1):29-34.
2013: Yoshikiyo Ito; Koichi Akashi; Yong Chong; Toshinobu Maki; Toshihiro Miyamoto; Tomohiko Kamimura
Nilotinib exacerbates diabetes mellitus by decreasing secretion of endogenous insulin.
International journal of hematology 2013;97(1):135-8.
2012: Kenjirou Kamezaki; Koichi Ohshima; Nobuyuki Shimono; Yukiko Harada; Koichi Akashi
[Diagnostic usefulness of FDG-PET/CT in multiple primary osseous Hodgkin lymphoma].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2012;53(12):2003-7.
2012: Takuro Kuriyama; Toshihiro Miyamoto; Katsuto Takenaka; Takanori Teshima; Takuji Yamauchi; Goichi Yoshimoto; Shinya Daitoku; Naoki Harada; Hiromi Iwasaki; Yoshikane Kikushige; Junji Kishimoto; Kentaro Kohno; Yasunobu Abe; Koichi Akashi
Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
Blood 2012;120(19):4058-67.
2012: Tomohiko Kamimura; Toshihiro Miyamoto; Shuichiro Takashima; Noriko Yokota; Yong Chong; Yoshikiyo Ito; Koichi Akashi
Injection site reaction after subcutaneous administration of bortezomib in Japanese patients with multiple myeloma.
International journal of hematology 2012;96(4):525-7.
2012: Keita Uchino; Eishi Baba; Minako Hirahashi; Gen Hirano; Taichi Isobe; Hitoshi Kusaba; Tsuyoshi Shirakawa; Masazumi Tsuneyoshi; Koichi Akashi
Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells.
Experimental cell research 2012;318(15):1799-807.
2012: Yoshikane Kikushige; Koichi Akashi
TIM-3 as a therapeutic target for malignant stem cells in acute myelogenous leukemia.
Annals of the New York Academy of Sciences 2012;1266():118-23.
2012: Yasuo Mori; Koji Nagafuji; Shinji Shimoda; Nobuyuki Shimono; Shuichiro Takashima; Katsuto Takenaka; Takanori Teshima; Shingo Urata; Hiromi Iwasaki; Kenjirou Kamezaki; Koji Kato; Yoshikane Kikushige; Toshihiro Miyamoto; Koichi Akashi
Low incidence of adenovirus hemorrhagic cystitis following autologous hematopoietic stem cell transplantation in the rituximab era.
American journal of hematology 2012;87(8):828-30.
2012: Y Mori; Koji Nagafuji; K Takenaka; T Teshima; Tanenao Eto; H Iwasaki; Kenjirou Kamezaki; Koji Kato; T Miyamoto; Koichi Akashi
Validation of pretransplantation assessment of mortality risk score in the outcome of hematopoietic SCT in non-Caucasians.
Bone marrow transplantation 2012;47(8):1075-81.
2012: Katsuto Takenaka; Koichi Akashi
[Bone marrow failure syndrome (idiopathic hematopoietic disorders): progress in diagnosis and treatment. Topics: III. Diagnosis and treatments; 6. Management of myelofibrosis].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2012;101(7):1969-76.
2012: Yoshihiro Eriguchi; Hiromi Iwasaki; Kiminori Nakamura; Hideyo Oka; Shinji Shimoda; Sonoko Shimoji; Nobuyuki Shimono; Shuichiro Takashima; Koichi Akashi; Tokiyoshi Ayabe; Hidetaka Uryu; Takanori Teshima
Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins.
Blood 2012;120(1):223-31.
2012: Katsuto Takenaka; Takanori Teshima; Tetsuya Eto; Naoki Harada; Hideho Henzan; Yoshikiyo Ito; Tomohiko Kamimura; Koji Kato; Toshihiro Miyamoto; Yasuo Mori; Koji Nagafuji; Yukiko Nishi; Ken Takase; Koichi Akashi
Initial low-dose valganciclovir as a preemptive therapy is effective for cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients.
International journal of hematology 2012;96(1):94-100.
2012: Akihito Harada; Anthony N Imbalzano; Daijiro Konno; Hiromi Kumamaru; Hitoshi Kurumizaka; Jun Odawara; Seiji Okada; Hirokazu Saiwai; Taro Tachibana; Toshiaki Tsubota; Tomohiko Yoshimi; Saori Yoshimura; Koichi Akashi; Yasuyuki Ohkawa
Chd2 interacts with H3.3 to determine myogenic cell fate.
The EMBO journal 2012;31(13):2994-3007.
2012: Shinji Shimoda; Koichi tsuneyama; Aftab A Ansari; M Eric Gershwin; Kenichi Harada; S Hisamoto; Hiromi Ishibashi; K Kikuchi; Patrick S C Leung; Mashio Nakamura; Yasuni Nakanuma; Hiroaki Niiro; Koichi Akashi
The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis.
Clinical and experimental immunology 2012;168(3):279-84.
2012: Tomohiko Kamimura; Noriaki Kawano; Toshihiro Miyamoto; Koji Nagafuji; Akihiko Numata; Takanori Teshima; Yong Chong; Shin Hayashi; Yoshikiyo Ito; Koichi Akashi
Successful treatment by donor lymphocyte infusion of adult T-cell leukemia/lymphoma relapse following allogeneic hematopoietic stem cell transplantation.
International journal of hematology 2012;95(6):725-30.
2012: Katsuto Takenaka; Koichi Akashi
[Leukemia stem cells: current understanding and future directions].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 2():139-45.
2012: Hiroaki Niiro; Kumiko Noda; Shun-Ichiro Ota; Takahiro Shima; Shinji Shimoda; Tadayoshi Taniyama; Hiroshi Tsukamoto; Hirofumi Tsuzuki; Yojiro Arinobu; Eishi Baba; Takahiko Horiuchi; Yasushi Inoue; Hiromi Iwasaki; Siamak Jabbarzadeh-Tabrizi; Yoshikane Kikushige; Koichi Akashi
CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells.
Blood 2012;119(10):2263-73.
2012: Tomohiko Kamimura; Toshihiro Miyamoto; Yusyu Ohno; Katsuto Takenaka; Chong Yong; Tetsuya Eto; Hideho Henzan; Yoshikiyo Ito; Koichi Akashi
[Clinical outcomes of allogeneic hematopoietic stem cell transplantation for adult primary myelofibrosis: retrospective analysis by Fukuoka BMT group].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2012;53(3):323-8.
2012: Eishi Baba; Taito Esaki; Hiromitsu Fujishima; Hitoshi Kusaba; Akitaka Makiyama; Kenji Mitsugi; Shuji Nakano; Risa Tanaka; Keita Uchino; Koichi Akashi
Phase 2 study of modified irinotecan and bolus 5-fluorouracil/l-leucovorin in Japanese metastatic colorectal cancer patients.
Advances in therapy 2012;29(3):287-96.
2012: Tetsuro Yamamoto; Shigeru Yoshizawa; Yojiro Arinobu; Akihito Hara; Shin-Ichi Harashima; Takahiko Horiuchi; Norihiko Inagaki; Yasushi Inoue; Takehiko Kaneko; Yoshihiro Kasamatsu; Yoichiro Kashiwagai; Haruhisa Machida; Junichi Maehara; Hisaaki Miyahara; Hiroaki Niiro; Eisuke Shono; Kenichi Suzawa; Tomoko Tahira; Kazuto Takamura; Kaoru Tsujioka; Hiroshi Tsukamoto; Naoki Uemura; Noriko Umegaki; Koichi Akashi
Hereditary angioedema in Japan: genetic analysis of 13 unrelated cases.
The American journal of the medical sciences 2012;343(3):210-4.
2012: Yasuo Mori; Koji Nagafuji; Seido Oku; Motoaki Shiratsuchi; Katsuto Takenaka; Takanori Teshima; Naoki Harada; Hiromi Iwasaki; Kenjiro Kamezaki; Koji Kato; Takuro Kuriyama; Toshihiro Miyamoto; Yasunobu Abe; Koichi Akashi
Different risk factors related to adenovirus- or BK virus-associated hemorrhagic cystitis following allogeneic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012;18(3):458-65.
2012: Akiko Sugiyama; Satoshi Takeuchi; Goichi Yoshimoto; Koichi Akashi; Shuji Fukagawa; Toshihiro Miyamoto; Yoichi Moroi; masutaka furue
Case of insulin edema occurring during intensive insulin therapy after bone marrow transplantation.
The Journal of dermatology 2012;39(2):172-5.
2012: Hiromi Kumamaru; Yasuyuki Ohkawa; Hideyuki Okano; Hirokazu Saiwai; Hisakata Yamada; Koichi Akashi; Yukihide Iwamoto; Kazu Kobayakawa; Kensuke Kubota; Seiji Okada
Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells.
Nature communications 2012;3():1140.
2012: Chiyo Mizuochi; Kenzaburo Tani; Manuela Tavian; Koichi Akashi; Katia Biasch; Stuart T Fraser; Yuka Horio; Yoshikane Kikushige; Daisuke Sugiyama
Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.
PloS one 2012;7(4):e35763.
2011: Taichi Isobe; Masato Komoda; Hitoshi Kusaba; Tsuyoshi Shirakawa; Shigeo Takaishi; Shingo Tamura; Takashi Ueki; Shuji Arita; Hiroshi Ariyama; Eishi Baba; Koichi Akashi
Human STEAP3 maintains tumor growth under hypoferric condition.
Experimental cell research 2011;317(18):2582-91.
2011: Tomohiko Kamimura; Toshihiro Miyamoto; Mine Harada; Koichi Akashi
Advances in therapies for acute promyelocytic leukemia.
Cancer science 2011;102(11):1929-37.
2011: G Nakaji; Keita Odashiro; S Yasuda; M Fujihara; M Fukata; Toru Maruyama; Koichi Akashi
Influence of common cardiac drugs on gastroesophageal reflux disease: multicenter questionnaire survey.
International journal of clinical pharmacology and therapeutics 2011;49(9):555-62.
2011: Eishi Baba; Taito Esaki; Hiromitsu Fujishima; Hitoshi Kusaba; Kenji Mitsugi; Tatsuma Morikita; Shuji Nakano; Hiroshi Ariyama; Koichi Akashi
Phase II study of sequential treatment with S-1 and cisplatin for metastatic gastric cancer.
Cancer chemotherapy and pharmacology 2011;68(3):611-7.
2011: Yoshikane Kikushige; Toshihiro Miyamoto; Yasuo Mori; Hiroaki Niiro; Takahiro Shima; Katsuto Takenaka; Shingo Urata; Takuji Yamauchi; Goichi Yoshimoto; Tetsuya Eto; Tadafumi Iino; Fumihiko Ishikawa; Hiromi Iwasaki; Koichi Akashi
Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia.
Cancer cell 2011;20(2):246-59.
2011: Hidetake Yabuuchi; Koichi Akashi; Mine Harada; Masamitsu Hatakenaka; Takahiko Horiuchi; Takeshi Kamitani; Yoshio Matsuo; Koji Nagafuji; Shuji Sakai; Shunya Sunami; Hiroshi Tsukamoto; Hiroshi Honda
Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis.
European journal of radiology 2011;79(2):e74-9.
2011: Katsuto Takenaka; Koichi Akashi
[Lymphoid malignancies: progress in diagnosis and treatment. Topics: I. Pathogenesis and pathophysiology--recent findings; 1. Leukemia stem cells in acute lymphoblastic leukemia].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(7):1753-64.
2011: Yojiro Arinobu; Koichi Akashi
[Myeloid lineage commitment from the hematopoietic stem cell].
Arerugī = [Allergy] 2011;60(7):817-22.
2011: Yoshikane Kikushige; Toshihiro Miyamoto; Koichi Akashi
[Specific surface markers of AML-leukemic stem cells].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2011;52(7):531-4.
2011: Takatoshi Aoki; Naoki Harada; Hiromi Iwasaki; Kenjiro Kamezaki; Toshihiro Miyamoto; Yasuo Mori; Koji Nagafuji; Nobuyuki Shimono; Katsuto Takenaka; Takanori Teshima; Takuji Yamauchi; Goichi Yoshimoto; Koichi Akashi
Successful allogeneic stem cell transplantation in two patients with acute myelogenous leukaemia and invasive aspergillosis by antifungal combination therapy.
Mycoses 2011;54(4):e255-9.
2011: T Kamimura; T Miyamoto; K Nagafuji; A Numata; Y Ohno; Y Takamatsu; K Takase; S Taniguchi; T Teshima; Koichi Akashi; Tanenao Eto; T Fujisaki; Hisashi Gondo; H Henzan; Y Ito; M Harada
Role of autotransplantation in the treatment of acute promyelocytic leukemia patients in remission: Fukuoka BMT Group observations and a literature review.
Bone marrow transplantation 2011;46(6):820-6.
2011: Shouichi Ohga; Masataka Ishimura; Goichi Yoshimoto; Toshihiro Miyamoto; Hidetoshi Takada; Tamami Tanaka; Koichi Ohshima; Yoshiyasu Ogawa; Ken-Ichi Imadome; Yasunobu Abe; Koichi Akashi; Toshiro Hara
Clonal origin of Epstein-Barr virus (EBV)-infected T/NK-cell subpopulations in EBV-positive T/NK-cell lymphoproliferative disorders of childhood.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011;51(1):31-7.
2011: Hiroshi Tsukamoto; Koji Nagafuji; Takahiko Horiuchi; Hiroki Mitoma; Hiroaki Niiro; Yojiro Arinobu; Yasushi Inoue; Kentaro To; Toshihiro Miyamoto; Hiromi Iwasaki; Takanori Teshima; Mine Harada; Koichi Akashi
Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis: predominant reconstitution of Th1 CD4+ T cells.
Rheumatology (Oxford, England) 2011;50(5):944-52.
2011: Shinji Shimoda; Kenichi Harada; Hiroaki Niiro; Ken Shirabe; Akinobu Taketomi; Yoshihiko Maehara; Koichi tsuneyama; Yasuni Nakanuma; Patrick S C Leung; Aftab A Ansari; M Eric Gershwin; Koichi Akashi
Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2011;53(4):1270-81.
2011: Makio Furukawa; Chikako Kiyohara; Hiroshi Tsukamoto; Hiroki Mitoma; Yasutaka Kimoto; Ayumi Uchino; Misato Nakagawa; Kensuke Oryoji; Terufumi Shimoda; Koichi Akashi; Mine Harada; Takahiko Horiuchi
Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus.
Rheumatology international 2011;31(3):365-76.
2011: Shuichiro Takashima; Masanori Kadowaki; Kazutoshi Aoyama; Motoko Koyama; Takeshi Oshima; Kazuma Tomizuka; Koichi Akashi; Takanori Teshima
The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells.
The Journal of experimental medicine 2011;208(2):285-94.
2011: Noriaki Kawano; Ikuo Kikuchi; Yuri Nagahiro; Hidenobu Ochiai; Nobuyuki Ono; Kazuya Shimoda; Akira Ueda; Shigehiro Uezono; Kiyoshi Yamashita; Shuro Yoshida; Daisuke Himeji; Naoko Ikeda; Fumihiko Ishikawa; Fumiko Kawano; Koichi Akashi
Clinical features and outcomes of 35 disseminated intravascular coagulation cases treated with recombinant human soluble thrombomodulin at a single institution.
Journal of clinical and experimental hematopathology : JCEH 2011;51(2):101-7.
2011: Jun Odawara; Koichi Akashi; Akihito Harada; Kazumitsu Maehara; Seiji Okada; Taro Tachibana; Tomohiko Yoshimi; Yasuyuki Ohkawa
The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach.
BMC genomics 2011;12():516.
2011: Hideki Shimazu; Koichi Akashi; Mitsuhiro Fukata; Toru Maruyama; Gen Nakaji; Keita Odashiro
Relationship between atrial fibrillation and gastroesophageal reflux disease: a multicenter questionnaire survey.
Cardiology 2011;119(4):217-23.
2011: Yasuo Mori; Katsuto Takenaka; Koichi Akashi; Naoki Harada; Hiromi Iwasaki; Koji Kato; Toshihiro Miyamoto; Kohta Miyawaki; Takanori Teshima
Diagnostic value of serum procalcitonin and C-reactive protein for infections after allogeneic hematopoietic stem cell transplantation versus nontransplant setting.
Internal medicine (Tokyo, Japan) 2011;50(19):2149-55.
2010: Yoshikane Kikushige; Takahiro Shima; Shin-ichiro Takayanagi; Shingo Urata; Toshihiro Miyamoto; Hiromi Iwasaki; Katsuto Takenaka; Takanori Teshima; Toshiyuki Tanaka; Yoshimasa Inagaki; Koichi Akashi
TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells.
Cell stem cell 2010;7(6):708-17.
2010: Hitoshi Kusaba; Taito Esaki; Kitaro Futami; Sinnosuke Tanaka; Hiromitsu Fujishima; Kenji Mitsugi; Kenji Sakai; Hiroshi Ariyama; Risa Tanaka; Naoko Kinugawa; Takashi Ueki; Rhuichi Mibu; Eishi Baba; Shuji Nakano; Koichi Akashi
Phase I/II study of a 3-week cycle of irinotecan and S-1 in patients with advanced colorectal cancer.
Cancer science 2010;101(12):2591-5.
2010: Tatsuya Sasaki; Chiyo Mizuochi; Yuka Horio; Kazuki Nakao; Koichi Akashi; Daisuke Sugiyama
Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse.
Development (Cambridge, England) 2010;137(23):3941-52.
2010: Yasuo Mori; Toshihiro Miyamoto; Koji Nagafuji; Kenjiro Kamezaki; Asataro Yamamoto; Noriyuki Saito; Koji Kato; Katsuto Takenaka; Hiromi Iwasaki; Naoki Harada; Yasunobu Abe; Takanori Teshima; Koichi Akashi
High incidence of human herpes virus 6-associated encephalitis/myelitis following a second unrelated cord blood transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(11):1596-602.
2010: Takahiro Wakasaki; Muneyuki Masuda; Hiroaki Niiro; Siamak Jabbarzadeh-Tabrizi; Kumiko Noda; Tadayoshi Taniyama; Shizuo Komune; Koichi Akashi
A critical role of c-Cbl-interacting protein of 85 kDa in the development and progression of head and neck squamous cell carcinomas through the ras-ERK pathway.
Neoplasia (New York, N.Y.) 2010;12(10):789-96.
2010: Yoshikane Kikushige; Toshihiro Miyamoto; Koichi Akashi
[Hematopoietic stem cells are primarily involved in pathogenesis of chronic lymphocytic leukemia].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2010;51(8):679-84.
2010: Seido Oku; Katsuto Takenaka; Takuro Kuriyama; Kotaro Shide; Takashi Kumano; Yoshikane Kikushige; Shingo Urata; Takuji Yamauchi; Chika Iwamoto; Haruko K Shimoda; Toshihiro Miyamoto; Koji Nagafuji; Junji Kishimoto; Kazuya Shimoda; Koichi Akashi
JAK2 V617F uses distinct signalling pathways to induce cell proliferation and neutrophil activation.
British journal of haematology 2010;150(3):334-44.
2010: Kalindi Parmar; Jungmin Kim; Stephen M Sykes; Akiko Shimamura; P Stuckert; Kaya Zhu; Abigail Hamilton; Mary Kathryn Deloach; Jeffery L Kutok; Koichi Akashi; D Gary Gilliland; Alan D'andrea
Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.
Stem cells (Dayton, Ohio) 2010;28(7):1186-95.
2010: Yasutaka Kimoto; Takahiko Horiuchi; Hiroshi Tsukamoto; Chikako Kiyohara; Hiroki Mitoma; Ayumi Uchino; Isao Furugo; Shigeru Yoshizawa; Akira Ueda; Shin-ichi Harashima; Takuya Sawabe; Tomoko Tahira; Kenshi Hayashi; Shigeru Yoshizawa; Terufumi Shimoda; Koichi Akashi; Mine Harada
Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.
Rheumatology (Oxford, England) 2010;49(7):1346-53.
2010: Yasuo Mori; Yoji Nagasaki; Kenjirou Kamezaki; Katsuto Takenaka; Hiromi Iwasaki; Naoki Harada; Toshihiro Miyamoto; Yasunobu Abe; Nobuyuki Shimono; Koichi Akashi; Takanori Teshima
High incidence of false-positive Aspergillus galactomannan test in multiple myeloma.
American journal of hematology 2010;85(6):449-51.
2010: T Aoki; Kenjirou Kamezaki; Takahisa Miyamoto; Koji Nagafuji; Yasuo Mori; T Yamauchi; Katsuto Takenaka; H Iwasaki; Naoki Harada; N Shimono; Takanori Teshima; Koichi Akashi
Cord blood stem cell transplantation in a patient with disseminated mucormycosis and acute myelogenous leukemia.
Transplant infectious disease : an official journal of the Transplantation Society 2010;12(3):277-9.
2010: Gen Nakaji; Masahiko Fujiwara; Mitsuhiro Fukata; Shioto Yasuda; Keita Odashiro; Toru Maruyama; Koichi Akashi
Open-loop, clockwise QT-RR hysteresis immediately before the onset of torsades de pointes in type 2 long QT syndrome.
Journal of electrocardiology 2010;43(3):261-3.
2010: Naoyasu Ueda; Yasushi Inoue; Daisuke Himeji; Yoshiya Shimao; Kensuke Oryoji; Hiroki Mitoma; Yojiro Arinobu; Hiroaki Niiro; Hiroshi Tsukamoto; Takahiko Horiuchi; Akira Ueda; Koichi Akashi
Wegener's granulomatosis detected initially by integrated 18F-fluorodeoxyglucose positron emission tomography/computed tomography.
Modern rheumatology / the Japan Rheumatism Association 2010;20(2):205-9.
2010: Shinji Shimoda; Kenichi Harada; Hiroaki Niiro; Akinobu Taketomi; Yoshihiko Maehara; Koichi tsuneyama; Kentaro Kikuchi; Yasuni Nakanuma; Ian R Mackay; M Eric Gershwin; Koichi Akashi
CX3CL1 (fractalkine): a signpost for biliary inflammation in primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2010;51(2):567-75.
2010: Ruriko Nishida; Yasuo Mori; Hiromi Iwasaki; Takahito Tokuyama; Kenjirou Kamezaki; Yoji Nagasaki; Hideyo Oka; Kohta Miyawaki; Noriyuki Saito; Katsuto Takenaka; Naoki Harada; Toshihiro Miyamoto; Takanori Teshima; Koichi Akashi
Pulmonary nocardiosis developed in a hematopoietic stem cell transplant recipient with bronchiolitis obliterans.
Internal medicine (Tokyo, Japan) 2010;49(14):1441-4.
2010: A Uchino; Hiroshi Tsukamoto; Hitoshi Nakashima; S Yoshizawa; Isao Furugo; Hiroki Mitoma; K Oryoji; T Shimoda; Hiroaki Niiro; Y Tada; T Yano; T Nonaka; Ryozo Oishi; Koichi Akashi; Takahiko Horiuchi
Tacrolimus is effective for lupus nephritis patients with persistent proteinuria.
Clinical and experimental rheumatology 2010;28(1):6-12.
2010: Kyoko Ariyoshi; Toru Maruyama; Keita Odashiro; Koichi Akashi; Takehiko Fujino; Nobuhiro Uyesaka
Impaired erythrocyte filterability of spontaneously hypertensive rats: investigation by nickel filtration technique.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(1):129-36.
2010: Yasuo Mori; Takatoshi Aoki; Katsuto Takenaka; Takuji Yamauchi; Asataro Yamamoto; Kenjirou Kamezaki; Hiromi Iwasaki; Naoki Harada; Toshihiro Miyamoto; Koji Nagafuji; Takanori Teshima; Koichi Akashi
Successful treatment of refractory advanced nasal NK/T cell lymphoma with unrelated cord blood stem cell transplantation incorporating focal irradiation.
International journal of hematology 2010;91(1):107-11.
2010: H Katsuta; T Akashi; R Katsuta; M Nagaya; D Kim; Y Arinobu; M Hara; Susan Bonner-Weir; A J Sharma; Koichi Akashi; Gordon C Weir
Single pancreatic beta cells co-express multiple islet hormone genes in mice.
Diabetologia 2010;53(1):128-38.
2009: Goichi Yoshimoto; Toshihiro Miyamoto; Siamak Jabbarzadeh-Tabrizi; Tadafumi Iino; Jennifer L Rocnik; Yoshikane Kikushige; Yasuo Mori; Takahiro Shima; Hiromi Iwasaki; Katsuto Takenaka; Koji Nagafuji; Shin-ichi Mizuno; Hiroaki Niiro; Gary D Gilliland; Koichi Akashi
FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation.
Blood 2009;114(24):5034-43.
2009: Yoshihiro Shibata; Hiroshi Ariyama; Eishi Baba; Yasushi Takii; Taito Esaki; Kenji Mitsugi; Tanji Tsuchiya; Hitoshi Kusaba; Koichi Akashi; Shuji Nakano
Oxaliplatin-induced allergic reaction in patients with colorectal cancer in Japan.
International journal of clinical oncology 2009;14(5):397-401.
2009: Takuji Yamauchi; Yasuo Mori; Toshihiro Miyamoto; Kenjirou Kamezaki; Takatoshi Aoki; Asataro Yamamoto; Katsuto Takenaka; Hiromi Iwasaki; Naoki Harada; Koji Nagafuji; Takanori Teshima; Koichi Akashi
Second unrelated cord blood transplantation using a reduced-intensity conditioning regimen combined with gemtuzumab ozogamicin in patients with relapsed acute myelogenous leukemia.
International journal of hematology 2009;90(3):416-20.
2009: Koichi Akashi
Lymphoid lineage fate decision of hematopoietic stem cells.
Annals of the New York Academy of Sciences 2009;1176():18-25.
2009: Takanori Teshima; Koji Nagafuji; Hideho Henzan; Koichi Miyamura; Ken Takase; Michihiro Hidaka; Toshihiro Miyamoto; Katsuto Takenaka; Koichi Akashi; Mine Harada
Rituximab for the treatment of corticosteroid-refractory chronic graft-versus-host disease.
International journal of hematology 2009;90(2):253-60.
2009: Yoji Nagasaki; Yoshihiro Eriguchi; Yujiro Uchida; Noriko Miyake; Yoriko Maehara; Masako Kadowaki; Mine Harada; Koichi Akashi; Nobuyuki Shimono
Combination therapy with micafungin and amphotericin B for invasive pulmonary aspergillosis in an immunocompromised mouse model.
The Journal of antimicrobial chemotherapy 2009;64(2):379-82.
2009: K Kohno; Koji Nagafuji; H Tsukamoto; T Horiuchi; K Takase; K Aoki; Hideho Henzan; Kenjirou Kamezaki; Katsuto Takenaka; Takahisa Miyamoto; Takanori Teshima; M Harada; Koichi Akashi
Infectious complications in patients receiving autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases.
Transplant infectious disease : an official journal of the Transplantation Society 2009;11(4):318-23.
2009: Ilona Kalaszczynska; Yan Geng; Tadafumi Iino; Shin-ichi Mizuno; Yoon Choi; Ilona Kondratiuk; Daniel P Silver; Debra J Wolgemuth; Koichi Akashi; Piotr Sicinski
Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells.
Cell 2009;138(2):352-65.
2009: Hirofumi Nakamura; Masahiko Fujiwara; Gen Nakaji; Shioto Yasuda; Eiji Karashima; Shin-ichi Hiramatsu; Keita Odashiro; Toru Maruyama; Koichi Akashi
Case of atrial tachycardia originating from giant coronary sinus connected to persistent left superior vena cava: successful catheter ablation guided by noncontact mapping.
Fukuoka igaku zasshi = Hukuoka acta medica 2009;100(7):258-64.
2009: Keizo Anzai; Koji Fukagawa; Ryuichi Iwakiri; Kazuma Fujimoto; Koichi Akashi; Patrick Tso
Increased lipid absorption and transport in the small intestine of zucker obese rats.
Journal of clinical biochemistry and nutrition 2009;45(1):82-5.
2009: Yoji Nagasaki; Toshihiro Miyamoto; Hideho Henzan; Koji Nagafuji; Mine Harada; Koichi Akashi
Longstanding remission of adult onset Still's disease under imatinib therapy in a patient with chronic myelogenous leukemia.
The Journal of rheumatology 2009;36(6):1349-51.
2009: Yojiro Arinobu; Hiromi Iwasaki; Koichi Akashi
Origin of basophils and mast cells.
Allergology international : official journal of the Japanese Society of Allergology 2009;58(1):21-8.
2009: Katsuto Takenaka; Tetsuya Eto; Koji Nagafuji; Kenjirou Kamezaki; Yayoi Matsuo; Goichi Yoshimoto; Naoki Harada; Maki Yoshida; Hideho Henzan; Ken Takase; Toshihiro Miyamoto; Koichi Akashi; Mine Harada; Takanori Teshima
Oral valganciclovir as preemptive therapy is effective for cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients.
International journal of hematology 2009;89(2):231-7.
2009: Motoko Koyama; Daigo Hashimoto; Kazutoshi Aoyama; Ken-ichi Matsuoka; Kennosuke Karube; Hiroaki Niiro; Mine Harada; Mitsune Tanimoto; Koichi Akashi; Takanori Teshima
Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells.
Blood 2009;113(9):2088-95.
2009: Akitaka Makiyama; Baoli Qin; Keita Uchino; Yoshihiro Shibata; Shuji Arita; Taichi Isobe; Gen Hirano; Hitoshi Kusaba; Eishi Baba; Koichi Akashi; Shuji Nakano
Schedule-dependent synergistic interaction between gemcitabine and oxaliplatin in human gallbladder adenocarcinoma cell lines.
Anti-cancer drugs 2009;20(2):123-30.
2009: Siamak Jabbarzadeh Tabrizi; Hiroaki Niiro; Mariko Masui; Goichi Yoshimoto; Tadafumi Iino; Yoshikane Kikushige; Takahiro Wakasaki; Eishi Baba; Shinji Shimoda; Toshihiro Miyamoto; Toshiro Hara; Koichi Akashi
T cell leukemia/lymphoma 1 and galectin-1 regulate survival/cell death pathways in human naive and IgM+ memory B cells through altering balances in Bcl-2 family proteins.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(3):1490-9.
2009: T Shima; Goichi Yoshimoto; Takahisa Miyamoto; Shuro Yoshida; Kenjirou Kamezaki; Katsuto Takenaka; H Iwasaki; Naoki Harada; Koji Nagafuji; Takanori Teshima; N Shimono; Koichi Akashi
Disseminated tuberculosis following second unrelated cord blood transplantation for acute myelogenous leukemia.
Transplant infectious disease : an official journal of the Transplantation Society 2009;11(1):75-7.
2009: Yasuo Mori; Hiromi Iwasaki; Kentaro Kohno; Goichi Yoshimoto; Yoshikane Kikushige; Aki Okeda; Naokuni Uike; Hiroaki Niiro; Katsuto Takenaka; Koji Nagafuji; Toshihiro Miyamoto; Mine Harada; Kiyoshi Takatsu; Koichi Akashi
Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor.
The Journal of experimental medicine 2009;206(1):183-93.
2009: Yayoi Matsuo; Kenjirou Kamezaki; Shoichiro Takeishi; Katsuto Takenaka; Tetsuya Eto; Atsushi Nonami; Toshihiro Miyamoto; Hiromi Iwasaki; Naoki Harada; Koji Nagafuji; Takanori Teshima; Koichi Akashi
Encephalomyelitis mimicking multiple sclerosis associated with chronic graft-versus-host disease after allogeneic bone marrow transplantation.
Internal medicine (Tokyo, Japan) 2009;48(16):1453-6.
2008: Takatoshi Aoki; Toshihiro Miyamoto; Shuro Yoshida; Asataro Yamamoto; Takuji Yamauchi; Goichi Yoshimoto; Yasuo Mori; Kenjirou Kamezaki; Hiromi Iwasaki; Katsuto Takenaka; Naoki Harada; Koji Nagafuji; Takanori Teshima; Koichi Akashi
Additional acquisition of t(1;21)(p32;q22) in a patient relapsing with acute myelogenous leukemia with NUP98-HOXA9.
International journal of hematology 2008;88(5):571-4.
2008: Tomoyuki Akashi; Hirokazu Shigematsu; Yoshiyuki Hamamoto; Hiromi Iwasaki; Shigeru Yatoh; Susan Bonner-Weir; Koichi Akashi; Gordon C Weir
Bone marrow or foetal liver cells fail to induce islet regeneration in diabetic Akita mice.
Diabetes/metabolism research and reviews 2008;24(7):585-90.
2008: Takahiro Shima; Goichi Yoshimoto; Atsushi Nonami; Shuro Yoshida; Kenjirou Kamezaki; Hiromi Iwasaki; Katsuto Takenaka; Toshihiro Miyamoto; Naoki Harada; Takanori Teshima; Koichi Akashi; Koji Nagafuji
Successful treatment of parainfluenza virus 3 pneumonia with oral ribavirin and methylprednisolone in a bone marrow transplant recipient.
International journal of hematology 2008;88(3):336-40.
2008: Shinji Shimoda; Hiroshi Miyakawa; Minoru Nakamura; Hiromi Ishibashi; Kentaro Kikuchi; hiroto kita; Hiroaki Niiro; Youjirou Arinobu; Nobuyuki Ono; Ian R Mackay; M Eric Gershwin; Koichi Akashi
CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in AMA-negative primary biliary cirrhosis.
Journal of autoimmunity 2008;31(2):110-5.
2008: Tadahisa Shono; Nobuhiko Yokoyama; Toshio Uesaka; Junya Kuroda; Ryu Takeya; Tomoko Yamasaki; Toshiyuki Amano; Masahiro Mizoguchi; Satoshi O Suzuki; Hiroaki Niiro; Kyoko Miyamoto; Koichi Akashi; Toru Iwaki; Hideki Sumimoto; Tomio Sasaki
Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival.
International journal of cancer. Journal international du cancer 2008;123(4):787-92.
2008: Yoshikane Kikushige; Goichi Yoshimoto; Toshihiro Miyamoto; Tadafumi Iino; Yasuo Mori; Hiromi Iwasaki; Hiroaki Niiro; Katsuto Takenaka; Koji Nagafuji; Mine Harada; Fumihiko Ishikawa; Koichi Akashi
Human Flt3 is expressed at the hematopoietic stem cell and the granulocyte/macrophage progenitor stages to maintain cell survival.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7358-67.
2008: Alan B Cantor; Hiromi Iwasaki; Yojiro Arinobu; Tyler B Moran; Hirokazu Shigematsu; Matthew R Sullivan; Koichi Akashi; Stuart H Orkin
Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage.
The Journal of experimental medicine 2008;205(3):611-24.
2007: Fumihiko Ishikawa; Hiroaki Niiro; Tadafumi Iino; Shuro Yoshida; Noriyuki Saito; Shinya Onohara; Toshihiro Miyamoto; Hiroko Minagawa; Shin-Ichiro Fujii; Leonard D Shultz; Mine Harada; Koichi Akashi
The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.
Blood 2007;110(10):3591-660.
2007: Fumihiko Ishikawa; Shuro Yoshida; Yoriko Saito; Atsushi Hijikata; Hiroshi Kitamura; Satoshi Tanaka; Ryu Nakamura; Toru Tanaka; Hiroko Tomiyama; Noriyuki Saito; Mitsuhiro Fukata; Toshihiro Miyamoto; Bonnie Lyons; Koichi Ohshima; Naoyuki Uchida; Shuichi Taniguchi; Osamu Ohara; Koichi Akashi; Mine Harada; Leonard D Shultz
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.
Nature biotechnology 2007;25(11):1315-21.
2007: H Iwasaki; Koichi Akashi
Hematopoietic developmental pathways: on cellular basis.
Oncogene 2007;26(47):6687-96.
2007: Yojiro Arinobu; Shin-ichi Mizuno; Yong Chong; Hirokazu Shigematsu; Tadafumi Iino; Hiromi Iwasaki; Thomas Graf; Robin Mayfield; Susan Chan; Philippe Kastner; Koichi Akashi
Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages.
Cell stem cell 2007;1(4):416-27.
2007: Kumi Yoshida; Yoshikazu Yonemitsu; Sakura Tanaka; Shuro Yoshida; Satoko Shibata; Haruhiko Kondo; Shinji Okano; Fumihiko Ishikawa; Koichi Akashi; Makoto Inoue; Mamoru Hasegawa; Katsuo Sueishi
In vivo repopulation of cytoplasmically gene transferred hematopoietic cells by temperature-sensitive mutant of recombinant Sendai viral vector.
Biochemical and biophysical research communications 2007;361(3):811-6.
2007: Mark W Feinberg; Akm Khyrul Wara; Zhuoxiao Cao; Maria A Lebedeva; Frank Rosenbauer; Hiromi Iwasaki; Hideyo Hirai; Jonathan P Katz; Richard L Haspel; Susan Gray; Koichi Akashi; Julie Segre; Klaus kaestner; Daniel G Tenen; Mukesh K Jain
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation.
The EMBO journal 2007;26(18):4138-48.
2007: Yasuo Mori; Goichi Yoshimoto; Takashi Kumano; Toshihiro Miyamoto; Tadafumi Iino; Katsuto Takenaka; Hiromi Iwasaki; Naoki Harada; Naoko Kinukawa; Koji Nagafuji; Takanori Teshima; Kazuya Shimoda; Koichi Akashi; Mine Harada
Distinctive expression of myelomonocytic markers and down-regulation of CD34 in acute myelogenous leukaemia with FLT3 tandem duplication and nucleophosmin mutation.
European journal of haematology 2007;79(1):17-24.
2007: Hiromi Iwasaki; Koichi Akashi
Myeloid lineage commitment from the hematopoietic stem cell.
Immunity 2007;26(6):726-40.
2007: Koichi Akashi
Cartography of hematopoietic stem cell commitment dependent upon a reporter for transcription factor activation.
Annals of the New York Academy of Sciences 2007;1106():76-81.
2007: Takahiro Maeda; Taha Merghoub; Robin M Hobbs; Lin Dong; Manami Maeda; Johannes L Zakrzewski; Marcel R M van den Brink; Arthur Zelent; Hirokazu Shigematsu; Koichi Akashi; Julie T Feldstein; Giorgio Cattoretti; Pier Paolo Pandolfi
Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF.
Science (New York, N.Y.) 2007;316(5826):860-6.
2007: Glen D Raffel; Thomas Mercher; Hirokazu Shigematsu; Ifor Williams; Dana E Cullen; Koichi Akashi; Olivier A Bernard; D Gary Gilliland
Ott1(Rbm15) has pleiotropic roles in hematopoietic development.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):6001-6.
2007: Tatiana G Jones; Tatiana G Jones; Graham M Lord; Laurie H Glimcher; Jenny Hallgren; Yojiro Arinobu; Koichi Akashi; Alison M Paterson; Michael A Gurish; Francis W Luscinskas
Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.
The Journal of experimental medicine 2007;204(2):431-9.
2007: Kenjirou Kamezaki; Toshihiro Miyamoto; Tomoko Henzan; Akihiko Numata; Hiromi Iwasaki; Koji Nagafuji; Mine Harada; Takanori Teshima; Koichi Akashi
Collection of mobilized peripheral blood stem cells from a donor with severe iron deficient anemia.
Journal of clinical apheresis 2007;22(5):292-4.
2006: Hiromi Iwasaki; Koichi Akashi
Thymus exclusivity: all the right conditions for T cells.
Immunity 2006;25(5):697-700.
2006: Hiromi Iwasaki; Shin-ichi Mizuno; Yojiro Arinobu; Hidetoshi Ozawa; Yasuo Mori; Hirokazu Shigematsu; Kiyoshi Takatsu; Daniel G Tenen; Koichi Akashi
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Genes & development 2006;20(21):3010-21.
2006: Ewa Sicinska; Young-Mi Lee; Judith Gits; Hirokazu Shigematsu; Qunyan Yu; Vivienne Rebel; Yan Geng; Christopher J Marshall; Koichi Akashi; David M Dorfman; Ivo P Touw; Piotr Sicinski
Essential role for cyclin D3 in granulocyte colony-stimulating factor-driven expansion of neutrophil granulocytes.
Molecular and cellular biology 2006;26(21):8052-60.
2006: Iris T Chan; Jeffery L Kutok; Ifor Williams; Sarah Cohen; Sandra Moore; Hirokazu Shigematsu; Timothy J Ley; Koichi Akashi; Michelle M Le Beau; D Gary Gilliland
Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.
Blood 2006;108(5):1708-15.
2006: Hideyo Hirai; Pu Zhang; Tajhal Dayaram; Christopher J Hetherington; Shin-ichi Mizuno; Jiro Imanishi; Koichi Akashi; Daniel G Tenen
C/EBPbeta is required for 'emergency' granulopoiesis.
Nature immunology 2006;7(7):732-9.
2006: Koichi Akashi; Hideo Yanai; J Nishikawa; M Satake; Yasuhiro Fukagawa; Takeshi Okamoto; I Sakaida
Ulcerous change decreases the accuracy of endoscopic ultrasonography diagnosis for the invasive depth of early gastric cancer.
International journal of gastrointestinal cancer 2006;37(4):133-8.
2006: Frank Rosenbauer; Bronwyn M. Owens; Li Yu; Joseph R Tumang; Ulrich Steidl; Jeffery L Kutok; Linda K Clayton; Katharina Wagner; Marina Scheller; Hiromi Iwasaki; Chunhui Liu; Björn Hackanson; Koichi Akashi; Achim Leutz; Thomas L Rothstein; Christoph Plass; Daniel G Tenen
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
Nature genetics 2006;38(1):27-37.
2005: Yojiro Arinobu; Hiromi Iwasaki; Michael F Gurish; Shin-ichi Mizuno; Hirokazu Shigematsu; Hidetoshi Ozawa; Daniel G Tenen; K Frank Austen; Koichi Akashi
Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):18105-10.
2005: Fumihiko Ishikawa; Masaki Yasukawa; Bonnie Lyons; Shuro Yoshida; Toshihiro Miyamoto; Goichi Yoshimoto; Takeshi Watanabe; Koichi Akashi; Leonard D Shultz; Mine Harada
Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.
Blood 2005;106(5):1565-73.
2005: Hiromi Iwasaki; Chamorro Somoza; Hirokazu Shigematsu; Estelle A Duprez; Junko Iwasaki-Arai; Shin-Ichi Mizuno; Yojiro Arinobu; Kristin Geary; Pu Zhang; Tajhal Dayaram; Maris L Fenyus; Shannon Elf; Susan Chan; Philippe Kastner; Claudia S Huettner; Richard Murray; Daniel G Tenen; Koichi Akashi
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.
Blood 2005;106(5):1590-600.
2005: N Kawano; Fumihiko Ishikawa; Kazuya Shimoda; M Yasukawa; Koji Nagafuji; Toshihiro Miyamoto; Eishi Baba; T Tanaka; S Yamasaki; Hisashi Gondo; T Otsuka; Koichi Ohshima; L D Shultz; Koichi Akashi; Mine Harada
Efficient engraftment of primary adult T-cell leukemia cells in newborn NOD/SCID/beta2-microglobulin(null) mice.
Leukemia 2005;19(8):1384-90.
2005: Joseph D Growney; Hirokazu Shigematsu; Zhe Li; Benjamin H Lee; Jennifer Adelsperger; Rebecca Rowan; David P Curley; Jeffery L Kutok; Koichi Akashi; Ifor Williams; Nancy A Speck; D Gary Gilliland
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.
Blood 2005;106(2):494-504.
2005: Hiromi Iwasaki; Shin-ichi Mizuno; Robin Mayfield; Hirokazu Shigematsu; Yojiro Arinobu; Brian Seed; Michael F Gurish; Kiyoshi Takatsu; Koichi Akashi
Identification of eosinophil lineage-committed progenitors in the murine bone marrow.
The Journal of experimental medicine 2005;201(12):1891-7.
2005: Toshihiro Miyamoto; Koichi Akashi
Lineage promiscuous expression of transcription factors in normal hematopoiesis.
International journal of hematology 2005;81(5):361-7.
2005: Koichi Akashi
Lineage promiscuity and plasticity in hematopoietic development.
Annals of the New York Academy of Sciences 2005;1044():125-31.
2005: Takeshi Inukai; Toshiya Inaba; Jinjun Dang; Ryoko Kuribara; Keiya Ozawa; Atsushi Miyajima; Wenshu Wu; A Thomas Look; Yojiro Arinobu; Hiromi Iwasaki; Koichi Akashi; Keiko Kagami; Kumiko Goi; Kanji Sugita; Shinpei Nakazawa
TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down-regulating expression of the common beta chain of cytokine receptors.
Blood 2005;105(11):4437-44.
2005: Koichi Akashi; David Traver; Leonard I Zon
The complex cartography of stem cell commitment.
Cell 2005;121(2):160-2.
2005: Yutaka Okuno; Gang Huang; Frank Rosenbauer; Erica K. Evans; Hanna S Radomska; Hiromi Iwasaki; Koichi Akashi; Françoise Moreau-Gachelin; Youlin Li; Pu Zhang; Berthold Göttgens; Daniel G Tenen
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element.
Molecular and cellular biology 2005;25(7):2832-45.
2005: Joseph T Opferman; Hiromi Iwasaki; Christy C Ong; Heikyung Suh; Shin-ichi Mizuno; Koichi Akashi; Stanley J Korsmeyer
Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.
Science (New York, N.Y.) 2005;307(5712):1101-4.
2005: M Golam Mohi; Ifor Williams; Charles R Dearolf; Gordon Chan; Jeffery L Kutok; Sarah Cohen; Kelly Morgan; Christina L Boulton; Hirokazu Shigematsu; Heike Keilhack; Koichi Akashi; D Gary Gilliland; Benjamin G Neel
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.
Cancer cell 2005;7(2):179-91.
2005: Jing Wang; Hiromi Iwasaki; Andrei V Krivtsov; Phillip G Febbo; Aaron R Thorner; Patricia Ernst; Ema Anastasiadou; Jeffery L Kutok; Scott C Kogan; Sandra S Zinkel; Jill K Fisher; Jay L Hess; Todd R Golub; Scott A Armstrong; Koichi Akashi; Stanley J Korsmeyer
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
The EMBO journal 2005;24(2):368-81.
2005: Steffen Koschmieder; Berthold Göttgens; Pu Zhang; Junko Iwasaki-Arai; Koichi Akashi; Jeffery L Kutok; Tajhal Dayaram; Kristin Geary; Anthony R Green; Daniel G Tenen; Claudia S Huettner
Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis.
Blood 2005;105(1):324-34.
2004: Ming Yan; Sebastien A Burel; Luke Peterson; Eiki Kanbe; Hiromi Iwasaki; Anita Boyapati; Robert Hines; Koichi Akashi; Dong-Er Zhang
Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17186-91.
2004: Koichi Akashi
[Stem cell system and regenerative medicine].
Fukuoka igaku zasshi = Hukuoka acta medica 2004;95(12):314-20.
2004: Brian J P Huntly; Hirokazu Shigematsu; Kenji Deguchi; Benjamin H Lee; Shinichi Mizuno; Nicole Duclos; Rebecca Rowan; Sonia M Amaral; David P Curley; Ifor Williams; Koichi Akashi; D Gary Gilliland
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.
Cancer cell 2004;6(6):587-96.
2004: Pu Zhang; Junko Iwasaki-Arai; Hiromi Iwasaki; Maris L Fenyus; Tajhal Dayaram; Bronwyn M. Owens; Hirokazu Shigematsu; Elena Levantini; Claudia S Huettner; Julie Lekstrom-Himes; Koichi Akashi; Daniel G Tenen
Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha.
Immunity 2004;21(6):853-63.
2004: Katarzyna Kozar; Maria A Ciemerych; Vivienne Rebel; Hirokazu Shigematsu; Agnieszka Zagozdzon; Ewa Sicinska; Yan Geng; Qunyan Yu; Shoumo Bhattacharya; Roderick T Bronson; Koichi Akashi; Piotr Sicinski
Mouse development and cell proliferation in the absence of D-cyclins.
Cell 2004;118(4):477-91.
2004: Hirokazu Shigematsu; Boris Reizis; Hiromi Iwasaki; Shin-ichi Mizuno; Dan Hu; David Traver; Philip Leder; Nobuo Sakaguchi; Koichi Akashi
Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin.
Immunity 2004;21(1):43-53.
2004: Frank Rosenbauer; Katharina Wagner; Jeffery L Kutok; Hiromi Iwasaki; Michelle M Le Beau; Yutaka Okuno; Koichi Akashi; Steven Fiering; Daniel G Tenen
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.
Nature genetics 2004;36(6):624-30.
2004: Iris T Chan; Jeffery L Kutok; Ifor Williams; Sarah Cohen; Lauren Kelly; Hirokazu Shigematsu; Leisa Johnson; Koichi Akashi; David A Tuveson; Tyler Jacks; D Gary Gilliland
Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.
The Journal of clinical investigation 2004;113(4):528-38.
2004: David Traver; Koichi Akashi
Lineage commitment and developmental plasticity in early lymphoid progenitor subsets.
Advances in immunology 2004;83():1-54.
2003: Linheng Li; Koichi Akashi
Unraveling the molecular components and genetic blueprints of stem cells.
BioTechniques 2003;35(6):1233-9.
2003: Michael K Richards; Fulu Liu; Hiromi Iwasaki; Koichi Akashi; Daniel C Link
Pivotal role of granulocyte colony-stimulating factor in the development of progenitors in the common myeloid pathway.
Blood 2003;102(10):3562-8.
2003: Min Ye; Hiromi Iwasaki; Catherine V Laiosa; Matthias Stadtfeld; Huafeng Xie; Susanne Heck; Bjorn Clausen; Koichi Akashi; Thomas Graf
Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.
Immunity 2003;19(5):689-99.
2003: Claudia S Huettner; Steffen Koschmieder; Hiromi Iwasaki; Junko Iwasaki-Arai; Hanna S Radomska; Koichi Akashi; Daniel G Tenen
Inducible expression of BCR/ABL using human CD34 regulatory elements results in a megakaryocytic myeloproliferative syndrome.
Blood 2003;102(9):3363-70.
2003: Hiromi Iwasaki; Shin-ichi Mizuno; Richard A Wells; Alan B Cantor; Sumiko Watanabe; Koichi Akashi
GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages.
Immunity 2003;19(3):451-62.
2003: Siddhartha Jaiswal; David Traver; Toshihiro Miyamoto; Koichi Akashi; Eric Lagasse; Irving L Weissman
Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):10002-7.
2003: Tian H Chi; Mimi Wan; Peggy P Lee; Koichi Akashi; Daniel Metzger; Pierre Chambon; Christopher B Wilson; Gerald R Crabtree
Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development.
Immunity 2003;19(2):169-82.
2003: Junko Iwasaki-Arai; Hiromi Iwasaki; Toshihiro Miyamoto; Sumiko Watanabe; Koichi Akashi
Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion.
The Journal of experimental medicine 2003;197(10):1311-22.
2003: Susanne Heck; Olga Ermakova; Hiromi Iwasaki; Koichi Akashi; Chiao-Wang Sun; Thomas M Ryan; Tim M Townes; Thomas Graf
Distinguishable live erythroid and myeloid cells in beta-globin ECFP x lysozyme EGFP mice.
Blood 2003;101(3):903-6.
2003: Sandra S Zinkel; Christy C Ong; David O Ferguson; Hiromi Iwasaki; Koichi Akashi; Roderick T Bronson; Jeffery L Kutok; Frederick W Alt; Stanley J Korsmeyer
Proapoptotic BID is required for myeloid homeostasis and tumor suppression.
Genes & development 2003;17(2):229-39.
2003: Koichi Akashi; Xi He; Jie Chen; Hiromi Iwasaki; Chao Niu; Brooke Steenhard; Jiwang Zhang; Jeffrey S Haug; Linheng Li
Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis.
Blood 2003;101(2):383-9.
2002: Yutaka Okuno; Claudia S Huettner; Hanna S Radomska; Victoria Petkova; Hiromi Iwasaki; Koichi Akashi; Daniel G Tenen
Distal elements are critical for human CD34 expression in vivo.
Blood 2002;100(13):4420-6.
2002: Hanna S Radomska; David A Gonzalez; Yutaka Okuno; Hiromi Iwasaki; Andras Nagy; Koichi Akashi; Daniel G Tenen; Claudia S Huettner
Transgenic targeting with regulatory elements of the human CD34 gene.
Blood 2002;100(13):4410-9.
2002: Andrew BitMansour; Stacy M Burns; David Traver; Koichi Akashi; Christopher H Contag; Irving L Weissman; Janice M Y Brown
Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation.
Blood 2002;100(13):4660-7.
2002: Akira Inoue; Markus G Seidel; Wenshu Wu; Shintaro Kamizono; Adolfo Ferrando; Roderick T Bronson; Hiromi Iwasaki; Koichi Akashi; akira morimoto; Johann K Hitzler; Tamara I Pestina; Carl W Jackson; Ryuhei Tanaka; Miriam J Chong; Peter J McKinnon; Takeshi Inukai; Gerard C Grosveld; A Thomas Look
Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.
Cancer cell 2002;2(4):279-88.
2002: Markus G Manz; Toshihiro Miyamoto; Koichi Akashi; Irving L Weissman
Prospective isolation of human clonogenic common myeloid progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11872-7.
2002: Toshihiro Miyamoto; Hiromi Iwasaki; Boris Reizis; Min Ye; Thomas Graf; Irving L Weissman; Koichi Akashi
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment.
Developmental cell 2002;3(1):137-47.
2002: Pu Zhang; Erik Nelson; Hanna S Radomska; Junko Iwasaki-Arai; Koichi Akashi; Alan D Friedman; Daniel G Tenen
Induction of granulocytic differentiation by 2 pathways.
Blood 2002;99(12):4406-12.
2002: Thanyaphong Na Nakorn; David Traver; Irving L Weissman; Koichi Akashi
Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S.
The Journal of clinical investigation 2002;109(12):1579-85.
2002: Koichi Akashi
[Potential usefulness of hematopoietic stem cells in regenerative medicine].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2002;39(3):246-52.
2002: Yutaka Okuno; Hiromi Iwasaki; Claudia S Huettner; Hanna S Radomska; David A Gonzalez; Daniel G Tenen; Koichi Akashi
Differential regulation of the human and murine CD34 genes in hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6246-51.
2001: Yiqun Li; Yutaka Okuno; Pumin Zhang; Hanna S Radomska; H Chen; Hiromi Iwasaki; Koichi Akashi; M J Klemsz; Scott R McKercher; Richard A Maki; Daniel G Tenen
Regulation of the PU.1 gene by distal elements.
Blood 2001;98(10):2958-65.
2001: Koichi Akashi; T Nagasaka; N Nakashim; T Harada; Tomomitsu Okamoto; Shigehiko Mizutani; H Ishiko
Squamous cell carcinoma of the vulva and adjacent lesions treated at Nagoya University Hospital from 1965 to 1997.
Nagoya journal of medical science 2001;64(3-4):109-21.
2001: Y Yuan; Liming Zhou; T Miyamoto; H Iwasaki; N Harakawa; Christopher J Hetherington; Sebastien A Burel; E Lagasse; I L Weissman; Koichi Akashi; Dong-Er Zhang
AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10398-403.
2001: David Traver; Toshihiro Miyamoto; J Christensen; J Iwasaki-Arai; Koichi Akashi; Irving L Weissman
Fetal liver myelopoiesis occurs through distinct, prospectively isolatable progenitor subsets.
Blood 2001;98(3):627-35.
2001: K Ohtsuki; Motoya Hayase; Koichi Akashi; S Kopiwoda; Harry W Strauss
Detection of monocyte chemoattractant protein-1 receptor expression in experimental atherosclerotic lesions: an autoradiographic study.
Circulation 2001;104(2):203-8.
2001: Markus G Manz; David Traver; Koichi Akashi; Miriam Merad; Toshihiro Miyamoto; Edgar G Engleman; Irving L Weissman
Dendritic cell development from common myeloid progenitors.
Annals of the New York Academy of Sciences 2001;938():167-73; discussion 173-4.
2001: Markus G Manz; David Traver; Toshihiro Miyamoto; Irving L Weissman; Koichi Akashi
Dendritic cell potentials of early lymphoid and myeloid progenitors.
Blood 2001;97(11):3333-41.
2001: Reina E Mebius; T Miyamoto; J Christensen; J Domen; Tom Cupedo; Irving L Weissman; Koichi Akashi
The fetal liver counterpart of adult common lymphoid progenitors gives rise to all lymphoid lineages, CD45+CD4+CD3- cells, as well as macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(11):6593-601.
2001: S Mizuno ; Takahito Chijiwa; Takashi Okamura; Koichi Akashi; Yasuyuki Fukumaki; Yoshiyuki Niho; H Sasaki
Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia.
Blood 2001;97(5):1172-9.
2000: David Traver; Koichi Akashi; Markus G Manz; Miriam Merad; Toshihiro Miyamoto; Edgar G Engleman; Irving L Weissman
Development of CD8alpha-positive dendritic cells from a common myeloid progenitor.
Science (New York, N.Y.) 2000;290(5499):2152-4.
2000: Koichi Akashi; S Mizuno
Epstein-Barr virus-infected natural killer cell leukemia.
Leukemia & lymphoma 2000;40(1-2):57-66.
2000: Koichi Akashi; S Mizuno; Shuji Isaji
Comparative study of perioperative management of hepatic resection.
Digestive diseases and sciences 2000;45(10):1988-95.
2000: Motonari Kondo; David C Scherer; Toshihiro Miyamoto; Angela G King; Koichi Akashi; K Sugamura; Irving L Weissman
Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines.
Nature 2000;407(6802):383-6.
2000: S Mizuno; T Okamura; H Iwasaki; Y Ohno; Koichi Akashi; S Inaba; Y Niho
Hypercoagulable state following transfusions of granulocytes obtained from granulocyte colony-stimulating factor-stimulated donors.
International journal of hematology 2000;72(1):115-7.
2000: Toshihiro Miyamoto; Irving L Weissman; Koichi Akashi
AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7521-6.
2000: Koichi Akashi; L I Richie; T Miyamoto; William Henry Carr; Irving L Weissman
B lymphopoiesis in the thymus.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(10):5221-6.
2000: Koichi Akashi; Tannishtha Reya; Dennise Dalma-Weiszhausz; Irving L Weissman
Lymphoid precursors.
Current opinion in immunology 2000;12(2):144-50.
2000: Sazuku Nisitani; Anne B Satterthwaite; Koichi Akashi; I L Weissman; Owen N Witte; Matthew I Wahl
Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2737-42.
2000: Koichi Akashi; David Traver; Toshihiro Miyamoto; Irving L Weissman
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages.
Nature 2000;404(6774):193-7.
2000: Koichi Akashi; T Eto; T Shibuya; Kazuya Shimoda; Mine Harada; Y Niho
Aclarubicin induces differentiation of leukemic progenitors in myelodysplastic syndrome cooperating with granulocyte colony-stimulating factor.
Leukemia research 2000;24(3):243-8.
2000: Reina E Mebius; Koichi Akashi
Precursors to neonatal lymph nodes: LT beta+CD45+CD4+CD3- cells are found in fetal liver.
Current topics in microbiology and immunology 2000;251():197-201.
1999: Hiromichi Iwasaki; Kazuya Shimoda; Seiichi Okamura; Takeshi Otsuka; Koji Nagafuji; Noboru Harada; Y Ohno; Toshihiro Miyamoto; Koichi Akashi; Mine Harada; Yoshiyuki Niho
Production of soluble granulocyte colony-stimulating factor receptors from myelomonocytic cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6907-11.
1999: Koichi Akashi; Tsunefumi Shibuya; S Taniguchi; S Hayashi; Hiromichi Iwasaki; T Teshima; Y Takamatsu; Hisashi Gondo; Takashi Okamura; Mine Harada; Yoshiyuki Niho
Multiple autoimmune haemopoietic disorders and insidious clonal proliferation of large granular lymphocytes.
British journal of haematology 1999;107(3):670-3.
1999: K Ohtsuki; Koichi Akashi; Y Aoka; Francis G Blankenberg; S Kopiwoda; Jonathan F Tait; Harry W Strauss
Technetium-99m HYNIC-annexin V: a potential radiopharmaceutical for the in-vivo detection of apoptosis.
European journal of nuclear medicine 1999;26(10):1251-8.
1999: Sang-Kyu Ye; Kazushige Maki; T Kitamura; S Sunaga; Koichi Akashi; J Domen; I L Weissman; Tasuku Honjo; Koichi Ikuta
Induction of germline transcription in the TCRgamma locus by Stat5: implications for accessibility control by the IL-7 receptor.
Immunity 1999;11(2):213-23.
1999: Koichi Akashi; David Traver; Motonari Kondo; Irving L Weissman
Lymphoid development from hematopoietic stem cells.
International journal of hematology 1999;69(4):217-26.
1999: S Mizuno; Koichi Akashi; Koichi Ohshima; H Iwasaki; T Miyamoto; N Uchida; T Shibuya; Mine Harada; M Kikuchi; Yoshiyuki Niho
Interferon-gamma prevents apoptosis in Epstein-Barr virus-infected natural killer cell leukemia in an autocrine fashion.
Blood 1999;93(10):3494-504.
1999: Koichi Akashi; Motonari Kondo; Samuel Cheshier; Judith A Shizuru; Kimberly L Gandy; J Domen; Reina E Mebius; David Traver; Irving L Weissman
Lymphoid development from stem cells and the common lymphocyte progenitors.
Cold Spring Harbor symposia on quantitative biology 1999;64():1-12.
1998: Koichi Akashi; M Kondo; I L Weissman
Role of interleukin-7 in T-cell development from hematopoietic stem cells.
Immunological reviews 1998;165():13-28.
1998: David Traver; Koichi Akashi; Irving L Weissman; Eric Lagasse
Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia.
Immunity 1998;9(1):47-57.
1998: K Hahm; Bradley S Cobb; Aaron S McCarty; Karen E Brown; CA Klug; R Lee; Koichi Akashi; Irving L Weissman; Amanda G Fisher; Stephen T Smale
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.
Genes & development 1998;12(6):782-96.
1998: Koichi Akashi; Motonari Kondo; Irving L Weissman
Two distinct pathways of positive selection for thymocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2486-91.
1998: Hiroshige Hibasami; Takashi Komiya; Y Achiwa; Kazuko Ohnishi; T Kojima; K Nakanishi; Koichi Akashi; Y Hara
Induction of apoptosis in human stomach cancer cells by green tea catechins.
Oncology reports 1998;5(2):527-9.
1998: I Ito; Koichi Akashi; Kenji Sakimura; M Mishina; Hiroyuki Sugiyama
Distribution and development of NMDA receptor activities at hippocampal synapses examined using mice lacking the epsilon1 subunit gene.
Neuroscience research 1998;30(2):119-23.
1998: Koichi Akashi; Tsunefumi Shibuya; Minoru Nakamura; A Oogami; Mine Harada; Yoshiyuki Niho
Large granular lymphocytic leukaemia with a mixed T-cell/B-cell phenotype.
British journal of haematology 1998;100(2):291-4.
1997: Motonari Kondo; Irving L Weissman; Koichi Akashi
Identification of clonogenic common lymphoid progenitors in mouse bone marrow.
Cell 1997;91(5):661-72.
1997: Hisashi Gondo; Mine Harada; Takahisa Miyamoto; Katsuto Takenaka; K Tanimoto; S Mizuno; T Fujisaki; Koji Nagafuji; Shin Hayashi; Tanenao Eto; S Taniguchi; Koichi Akashi; Naoki Harada; K Yamasaki; Tsunefumi Shibuya; Eijo Matsuishi; Yuju Ohno; S Makino; Yasushi Takamatsu; M Murakawa; T Teshima; Y Hirota; Takashi Okamura; Naoko Kinukawa; Yoshiyuki Niho
Autologous peripheral blood stem cell transplantation for acute myelogenous leukemia.
Bone marrow transplantation 1997;20(10):821-6.
1997: Mine Harada; Koichi Akashi; S Hayashi; T Eto; Y Takamatsu; Takanori Teshima; Y Hirota; S Taniguchi; K Nagafuji; S Mizuno; H Gondo; Y Niho
Granulocyte colony-stimulating factor-combined marrow-ablative chemotherapy and autologous blood cell transplantation for the treatment of patients with acute myelogenous leukemia in first remission. The Fukouka Bone Marrow Transplant Group.
International journal of hematology 1997;66(3):297-301.
1997: Motonari Kondo; Koichi Akashi; J Domen; K Sugamura; Irving L Weissman
Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice.
Immunity 1997;7(1):155-62.
1997: Koichi Akashi; Motonari Kondo; U von Freeden-Jeffry; R Murray; Irving L Weissman
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice.
Cell 1997;89(7):1033-41.
1997: H L Aguila; Koichi Akashi; J Domen; Kimberly L Gandy; Eric Lagasse; Reina E Mebius; Sean J Morrison; Judith A Shizuru; Samuel Strober; N Uchida; DE Wright; Irving L Weissman
From stem cells to lymphocytes: biology and transplantation.
Immunological reviews 1997;157():13-40.
1997: Koichi Akashi; Masanori Yasuda; R Suto; H Fukuda; Johbu Itoh; Y Tsutsumi; R Yoshiyuki Osamura
A case of epithelioid hemangioendothelioma associated with an artery.
The Tokai journal of experimental and clinical medicine 1997;22(2):65-9.
1997: T Miyamoto; Koichi Akashi; S Hayashi; A Oogami; T Okamura; H Iwasaki; M Murakawa; M Harada; Y Niho
Pericentric inversion of chromosome 16 and eosinophilia in chronic myelomonocytic leukemia.
Cancer genetics and cytogenetics 1997;94(2):99-102.
1996: Y Sawae; Y Niho; T Okamura; H Gondo; Mitsuo Kozuru; Naokuni Uike; Koichiro Muta; T Goto; Youko Suehiro; M Kumakawa; Junji Nishimura; Yuji Yufu; H Ishikura; S Yamashita; S Hisano; E Morioka; H Nakajima; Tsunefumi Shibuya; K Yamasaki; N Harada; R Asayama; S Hayashi; Koichi Akashi; E Suematsu; Chika Kawasaki
[Comparison between monotherapy with imipenem/cilastatin sodium (IPM/CS) and combinations of IPM/CS and other drugs for treating bacterial infections in patients with hematopoietic disorders].
The Japanese journal of antibiotics 1996;49(12):1049-61.
1996: Sean J Morrison; A M Wandycz; Koichi Akashi; A Globerson; Irving L Weissman
The aging of hematopoietic stem cells.
Nature medicine 1996;2(9):1011-6.
1996: Koichi Akashi; Irving L Weissman
The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection.
Immunity 1996;5(2):147-61.
1996: S Mizuno; M Toyoshima; Y Niho; Hisashi Gondo; Takashi Okamura; T Otsuka; Y Asano; S Makino; S Taniguchi; Koichi Akashi; M Murakawa; Y Takamatsu; T Fukuda; H Ono; H Iwasaki; M Kuroiwa; Y Kanechi; K Takenaka; K Tanimoto; H Shigematsu; T Yokoyama; K Osaki; T Fukuyama; T Murakami; N Uchida
[Peripheral blood stem cell transplantation for acute leukemia].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1996;37(7):584-90.
1996: Takahisa Miyamoto; Koji Nagafuji; Koichi Akashi; M Harada; Taiichi Kyo; T Akashi; K Takenaka; S Mizuno; Hisashi Gondo; Takashi Okamura; Hiroo Dohy; Y Niho
Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia.
Blood 1996;87(11):4789-96.
1996: T Miyamoto; Koichi Akashi; S Hayashi; H Gondo; M Murakawa; K Tanimoto; M Harada; Y Niho
Serum concentration of the soluble interleukin-2 receptor for monitoring acute graft-versus-host disease.
Bone marrow transplantation 1996;17(2):185-90.
1996: M Harada; T Teshima; T Fujisaki; S Mizuno; T Miyamoto; Y Takamatsu; A Kubota; Y Ohno; M Kuroiwa; K Takenaka; T Eto; Koichi Akashi; H Gondo; T Okamura; S Inaba; Y Niho
Granulocyte colony-stimulating factor-induced mobilization of peripheral blood stem cells for autologous and allogeneic transplantation. Fukuoka Bone Marrow Transplantation Group.
Cancer chemotherapy and pharmacology 1996;38 Suppl():S115-9.
1995: Takahisa Miyamoto; Koji Nagafuji; M Harada; Tanenao Eto; T Fujisaki; A Kubota; Koichi Akashi; S Mizuno; K Takenaka; Taisuke Kanaji
Quantitative analysis of AML1/ETO transcripts in peripheral blood stem cell harvests from patients with t(8;21) acute myelogenous leukaemia.
British journal of haematology 1995;91(1):132-8.
1995: Koichi Ohshima; Masahiro Kikuchi; S Mizuno; Koichi Akashi; K Moriyama; S Yoneda; Morishige Takeshita; T Shibata
Hepatosinusoidal leukaemia/lymphoma consisting of Epstein-Barr virus-containing natural killer cell leukaemia/lymphoma and T-cell lymphoma; mimicking malignant histiocytosis.
Hematological oncology 1995;13(2):83-97.
1995: Takahisa Miyamoto; Koji Nagafuji; M Harada; K Yamasaki; Tsunefumi Shibuya; Hiromichi Iwasaki; Koichi Akashi; S Mizuno; Tanenao Eto; K Takenaka
Characterization of blasts from a patient with eosinophilic blast crisis of chronic myelogenous leukaemia.
British journal of haematology 1995;89(1):207-10.
1995: Y Takamatsu; M Harada; T Teshima; S Makino; S Inaba; Koichi Akashi; Tsunefumi Shibuya; Y Niho
Relationship of infused CFU-GM and CFU-Mk mobilized by chemotherapy with or without G-CSF to platelet recovery after autologous blood stem cell transplantation.
Experimental hematology 1995;23(1):8-13.
1994: Y Sumiyoshi; Koichi Akashi; Masahiro Kikuchi
Detection of human herpes virus 6 (HHV 6) in the skin of a patient with primary HHV 6 infection and erythroderma.
Journal of clinical pathology 1994;47(8):762-3.
1994: Koichi Akashi; S Hayashi; H Gondo; S Mizuno; M Harada; K Tamura; K Yamasaki; T Shibuya; N Uike; T Okamura
Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults.
British journal of haematology 1994;87(2):243-50.
1994: Y Takamatsu; T Teshima; Koichi Akashi; S Inaba; M Harada; Y Niho
Successful second autologous blood stem cell transplantation after G-CSF-combined conditioning for the treatment of high-risk acute myelogenous leukemia.
Bone marrow transplantation 1994;13(3):325-7.
1994: Tanenao Eto; Y Takamatsu; M Harada; Naoki Harada; Koichi Akashi; T Teshima; S Inaba; Takashi Okamura; Y Niho
Effects of macrophage colony-stimulating factor (M-CSF) on the mobilization of peripheral blood stem cells.
Bone marrow transplantation 1994;13(2):125-9.
1994: Hisashi Gondo; T Minematsu; M Harada; Koichi Akashi; S Hayashi; S Taniguchi; K Yamasaki; Tsunefumi Shibuya; Y Takamatsu; T Teshima
Cytomegalovirus (CMV) antigenaemia for rapid diagnosis and monitoring of CMV-associated disease after bone marrow transplantation.
British journal of haematology 1994;86(1):130-7.
1993: Hisashi Gondo; M Harada; S Taniguchi; Koichi Akashi; S Hayashi; T Teshima; Y Takamatsu; Tanenao Eto; Koji Nagafuji; K Yamasaki
Cyclosporine combined with methylprednisolone or methotrexate in prophylaxis of moderate to severe acute graft-versus-host disease.
Bone marrow transplantation 1993;12(5):437-41.
1993: Hisashi Gondo; M Harada; T Minematsu; Koichi Akashi; S Hayashi; S Taniguchi; K Yamasaki; Tsunefumi Shibuya; Y Takamatsu; Tanenao Eto
[Cytomegalovirus antigenemia in the differential diagnosis of pulmonary infiltrates after allogeneic bone marrow transplantation].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1993;34(11):1438-44.
1993: Koji Nagafuji; M Harada; T Teshima; Tanenao Eto; Y Takamatsu; Takashi Okamura; M Murakawa; Koichi Akashi; Y Niho
Hematopoietic progenitor cells from patients with adult T-cell leukemia-lymphoma are not infected with human T-cell leukemia virus type 1.
Blood 1993;82(9):2823-8.
1993: Koji Nagafuji; M Harada; Y Takamatsu; Tanenao Eto; T Teshima; T Kamura; Takashi Okamura; S Hayashi; Koichi Akashi; M Murakawa
Evaluation of leukaemic contamination in peripheral blood stem cell harvests by reverse transcriptase polymerase chain reaction.
British journal of haematology 1993;85(3):578-83.
1993: M Harada; Tsunefumi Shibuya; T Teshima; M Murakawa; Takashi Okamura; Y Niho; Hisashi Gondo; S Hayashi; Koichi Akashi; K Tamura
A randomized phase II trial of low-dose aclarubicin vs very low-dose cytosine arabinoside for treatment of myelodysplastic syndromes.
Leukemia research 1993;17(8):629-32.
1993: T Teshima; M Harada; Y Takamatsu; K Makino; S Inaba; Koichi Akashi; S Kondo; T Tanaka; Eiichi Ishii; Y Niho
Granulocyte colony-stimulating factor (G-CSF)-induced mobilization of circulating haemopoietic stem cells.
British journal of haematology 1993;84(4):570-3.
1993: Koichi Akashi; Y Eizuru; Y Sumiyoshi; T Minematsu; S Hara; M Harada; M Kikuchi; Y Niho; Yohji A Minamishima
Brief report: severe infectious mononucleosis-like syndrome and primary human herpesvirus 6 infection in an adult.
The New England journal of medicine 1993;329(3):168-71.
1993: Koichi Akashi; M Matsunaga; K Dan
[Influences of anesthetic method on post-cholecystectomy pain--a comparison between epidural and general anesthesia].
Masui. The Japanese journal of anesthesiology 1993;42(7):1038-42.
1993: Koichi Akashi; S Taniguchi; Koji Nagafuji; M Harada; T Shibuya; S Hayashi; Hisashi Gondo; Y Niho
B-lymphoid/myeloid stem cell origin in Ph-positive acute leukemia with myeloid markers.
Leukemia research 1993;17(7):549-55.
1993: S Mizuno; Koichi Akashi; Y Hirota; S Gyoten; I Matsumoto; M Harada; Y Niho
Filgrastim treatment of leukaemic transformation in myelodysplastic syndrome.
Lancet 1993;341(8858):1475-6.
1993: Koichi Akashi; S Mizuno; M Harada; N Kimura; M Kinjyo; T Shibuya; K Shimoda; M Takeshita; S Okamura; I Matsumoto
T lymphoid/myeloid bilineal crisis in chronic myelogenous leukemia.
Experimental hematology 1993;21(6):743-8.
1993: K Y Liu; Koichi Akashi; M Harada; Y Takamatsu; Y Niho
Kinetics of circulating haematopoietic progenitors during chemotherapy-induced mobilization with or without granulocyte colony-stimulating factor.
British journal of haematology 1993;84(1):31-8.
1993: Y Niho; Koichi Akashi; K Hayashida
[Basis of cytokines--history and present status].
Rinsho byori. The Japanese journal of clinical pathology 1993;41(4):355-60.
1993: Hisashi Gondo; M Harada; N Hara; N Harada; N Asou; S Hayashi; Koichi Akashi; Y Niho; T Minematsu; Yohji A Minamishima
[Idiopathic interstitial pneumonitis possibly associated with chronic graft-versus-host disease].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1993;34(2):183-9.
1993: Koichi Akashi
The role of interleukin-4 in the negative regulation of leukemia cell growth.
Leukemia & lymphoma 1993;9(3):205-9.
1993: Y Takamatsu; Koichi Akashi; M Harada; T Teshima; S Inaba; K Shimoda; Tanenao Eto; Tsunefumi Shibuya; Seiichi Okamura; Y Niho
Cytokine production by peripheral blood monocytes and T cells during haemopoietic recovery after intensive chemotherapy.
British journal of haematology 1993;83(1):21-7.
1992: Tanenao Eto; Koichi Akashi; M Harada; Tsunefumi Shibuya; Y Takamatsu; T Teshima; Y Niho
Biological characteristics of CD7 positive acute myelogenous leukaemia.
British journal of haematology 1992;82(3):508-14.
1992: T Teshima; M Harada; Y Takamatsu; K Makino; S Taniguchi; S Inaba; S Kondo; T Tanaka; Koichi Akashi; I Minamishima
Cytotoxic drug and cytotoxic drug/G-CSF mobilization of peripheral blood stem cells and their use for autografting.
Bone marrow transplantation 1992;10(3):215-20.
1992: S Taniguchi; M Harada; S Makino; Koichi Akashi; T Toyoshima; Y Takamatsu; S Kondo; T Tanaka; M Murakawa; K Gondo
[Autologous peripheral blood stem cell transplantation--an evaluation in adults].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1992;33(7):945-9.
1992: Kazuya Shimoda; Seiichi Okamura; N Harada; Wataru Ikematsu; S Kondo; Chika Kawasaki; Teruo Tanaka; T Etou; Koichi Akashi; Takashi Okamura
Granulocyte colony-stimulating factor receptors on human acute leukemia: biphenotypic leukemic cells possess granulocyte colony-stimulating factor receptors.
Cancer research 1992;52(11):3052-5.
1992: Koichi Akashi; M Harada
[Immunophenotypic analysis in acute leukemia].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(6):1229-35.
1992: Naokuni Uike; S Yamashita; K Obama; H Takahira; H Nakai; J Inazawa; T Umemura; Koichi Akashi; Mitsuo Kozuru
[i(17q) appearing in acute phase in Ph1-negative, BCR-negative CML].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1992;33(5):694-9.
1992: Koichi Akashi; Tsunefumi Shibuya; M Harada; A Oogami; T Teshima; Y Takamatsu; M Kikuchi; Y Niho
Interstitial 9q deletion in T-lymphoid/myeloid biphenotypic leukaemia.
British journal of haematology 1992;80(2):172-7.
1992: T Teshima; M Harada; Y Takamatsu; S Inaba; S Kondo; Koichi Akashi; Takashi Okamura; Y Niho
Folinic acid does not mobilize hemopoietic progenitors following repeated consolidation chemotherapy for acute leukemia.
Journal of clinical apheresis 1992;7(4):213-6.
1992: M Harada; S Taniguchi; T Teshima; S Makino; Y Takamatsu; Koichi Akashi; H Gondo; T Etoh; S Kondo; T Shibuya
Cryopreservation, cytokine mobilization, and autotransplantation of peripheral blood stem cells.
Progress in clinical and biological research 1992;377():297-308.
1991: S Makino; M Harada; Koichi Akashi; S Taniguchi; Tsunefumi Shibuya; S Inaba; Y Niho
A simplified method for cryopreservation of peripheral blood stem cells at -80 degrees C without rate-controlled freezing.
Bone marrow transplantation 1991;8(4):239-44.
1991: Koichi Akashi; M Harada; T Shibuya; K Fukagawa; N Kimura; K Sagawa; Y Yoshikai; T Teshima; M Kikuchi; Y Niho
Simultaneous occurrence of myelomonocytic leukemia and multiple myeloma: involvement of common leukemic progenitors and their developmental abnormality of "lineage infidelity".
Journal of cellular physiology 1991;148(3):446-56.
1991: T Teshima; S Kondo; S Inaba; Koichi Akashi; T Shibuya; M Harada; Y Niho
Folinic acid did not expand the peripheral blood stem cell pool during recovery from consolidation chemotherapy.
British journal of haematology 1991;78(4):583.
1991: Koichi Akashi; Tsunefumi Shibuya; M Harada; Y Takamatsu; Naokuni Uike; T Eto; Y Niho
Interleukin 4 suppresses the spontaneous growth of chronic myelomonocytic leukemia cells.
The Journal of clinical investigation 1991;88(1):223-30.
1991: Koichi Akashi; M Harada; Tsunefumi Shibuya; Tanenao Eto; Y Takamatsu; T Teshima; Y Niho
Effects of interleukin-4 and interleukin-6 on the proliferation of CD34+ and CD34- blasts from acute myelogenous leukemia.
Blood 1991;78(1):197-204.
1991: T Teshima; S Kondo; M Harada; Tsunefumi Shibuya; Takashi Okamura; Y Tamari; N Kimura; Koichi Akashi; Seiichi Okamura; Y Niho
Characterization of leukaemic basophil progenitors from chronic myelogenous leukaemia.
British journal of haematology 1991;78(1):55-9.
1991: M Harada; Koichi Akashi; Tsunefumi Shibuya; Y Takamatsu; Y Niho
Role of interleukin-4 in the negative regulation of proliferation of chronic myelomonocytic leukemia cells.
Annals of the New York Academy of Sciences 1991;628():156-64.
1991: K Takahashi; S Taniguchi; Koichi Akashi; K Fujimoto; T Sibuya; H Ishibashi; M Harada; Y Niho
Human recombinant granulocyte colony-stimulating factor for the treatment of autoimmune neutropenia.
Acta haematologica 1991;86(2):95-8.
1990: T Teshima; Tsunefumi Shibuya; M Harada; Koichi Akashi; S Taniguchi; Takashi Okamura; Y Niho
Granulocyte-macrophage colony-stimulating factor suppresses induction of neutrophil alkaline phosphatase synthesis by granulocyte colony-stimulating factor.
Experimental hematology 1990;18(4):316-21.
1990: Koichi Akashi; Tsunefumi Shibuya; M Harada; E Morioka; K Oshima; N Kimura; M Takeshita; M Kurokawa; M Kikuchi; Y Niho
Acute 'bilineal-biphenotypic' leukaemia.
British journal of haematology 1990;74(4):402-7.
1990: Koichi Akashi; Kohei Nagasawa; T Mayumi; E Yokota; N Oochi; T Kusaba
Successful treatment of refractory systemic lupus erythematosus with intravenous immunoglobulins.
The Journal of rheumatology 1990;17(3):375-9.
1990: Koichi Akashi; S Taniguchi; T Teshima; Tsunefumi Shibuya; Takashi Okamura; M Harada; Y Niho
Effect of N-methionine-free, bacterially synthesized recombinant human granulocyte-macrophage colony-stimulating factor in a primate model.
European journal of haematology 1990;44(2):100-5.
1990: T Teshima; Koichi Akashi; Tsunefumi Shibuya; S Taniguchi; Takashi Okamura; M Harada; I Sumida; M Hanada; Y Niho
Central nervous system involvement in adult T-cell leukemia/lymphoma.
Cancer 1990;65(2):327-32.
1990: Koichi Akashi; M Harada; Tsunefumi Shibuya; E Morioka; Takashi Okamura; Yoshinobu Asano; S Taniguchi; T Teshima; M Kikuchi; Y Niho
Clinical characteristics of hybrid leukemia: report of five cases.
Leukemia research 1990;14(2):145-53.
1989: Tsunefumi Shibuya; K Moriyama; M Harada; T Okamura; S Taniguchi; Koichi Akashi; R Mori; Y Niho
Herpes simplex virus in oral mucosal ulcers in patients with hematological malignancy.
Japanese journal of clinical oncology 1989;19(4):348-52.
1988: M Harada; S Hayashi; S Taniguchi; N Ohhara; Koichi Akashi; T Otsuka; T Shibuya; S Okamura; Y Niho
Role of T lymphocytes in the suppression of hematopoiesis: hematopoietic suppressive factors and their mRNA expression in activated T lymphocytes.
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society 1988;51(8):1531-9.
1988: Koichi Akashi; T Ishimaru; Y Tsuda; S Nagafuchi; R Itaya; Jun Hayashi; Y Sawae; Yoshito Kawachi; Y Niho
Purulent pericarditis caused by Streptococcus milleri.
Archives of internal medicine 1988;148(11):2446-7.
1986: K Matsumoto; Y Nakamura; Koichi Akashi; H Yamaguchi
HVJ (Sendai virus) stimulates release of interferon from leukocytes used once for interferon production.
The Journal of general virology 1986;67 ( Pt 4)():809-12.
1986: K Suzuki; M Yamada; Koichi Akashi; T Fujikura
Similarity of kinetics of three types of myeloperoxidase from human leukocytes and four types from HL-60 cells.
Archives of biochemistry and biophysics 1986;245(1):167-73.
1985: Y Bessho; Koichi Akashi; K Nakanishi; T Murata; M Yamauchi
[Postoperative care and rehabilitation of patients with liver cancer].
[Kango gijutsu] : [Nursing technique] 1985;31(14):1892-7.
1985: H Haruyama; Koichi Akashi; C Shimazaki; A Nishio; M Nakagawa; H Ijichi; K Nishida; M Taniwaki; S Misawa
[A case of acute myelomonocytic leukemia with variant chromosome 16 and marrow eosinophilia].
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society 1985;48(5):1236-40.
1985: Koichi Akashi; A Kirimoto; M Higashiyama; H Saka; T Komada
[Pre and postoperative management and nursing of patients with esophageal cancer--with special reference to postoperative complications].
[Kango gijutsu] : [Nursing technique] 1985;31(9):1225-32.
1984: G Oshima; Koichi Akashi; M Yamada
pH dependence of salt activation of human leukocyte elastase.
Archives of biochemistry and biophysics 1984;233(1):212-8.