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Martin Brodie

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Publications

TOP 3
Martin J Brodie
Road to refractory epilepsy: The Glasgow story.
Martin J Brodie; Ghazi A Bamagous; Sarah J E Barry; Patrick Kwan
Effect of dosage failed of first antiepileptic drug on subsequent outcome.
Martin J Brodie; Barry E Gidal; Scott Mintzer; Alison M Pack; Charles J Vecht; Dieter Schmidt
Enzyme induction with antiepileptic drugs: cause for concern?

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All Publications

2013: Martin J Brodie
Road to refractory epilepsy: The Glasgow story.
Epilepsia 2013;54 Suppl 2():5-8.
2013: Martin J Brodie; Ghazi A Bamagous; Sarah J E Barry; Patrick Kwan
Effect of dosage failed of first antiepileptic drug on subsequent outcome.
Epilepsia 2013;54(1):194-8.
2013: Martin J Brodie; Barry E Gidal; Scott Mintzer; Alison M Pack; Charles J Vecht; Dieter Schmidt
Enzyme induction with antiepileptic drugs: cause for concern?
Epilepsia 2013;54(1):11-27.
2012: Martin J Brodie; Patrick Kwan
Current position of phenobarbital in epilepsy and its future.
Epilepsia 2012;53 Suppl 8():40-6.
2012: Martin J Brodie
Novel trial designs for monotherapy.
Epileptic disorders : international epilepsy journal with videotape 2012;14(2):132-7.
2012: Linda J Stephen; Martin J Brodie
Antiepileptic drug monotherapy versus polytherapy: pursuing seizure freedom and tolerability in adults.
Current opinion in neurology 2012;25(2):164-72.
2012: Linda J Stephen; Murray Forsyth; Kevin Kelly; Martin J Brodie
Antiepileptic drug combinations--have newer agents altered clinical outcomes?
Epilepsy research 2012;98(2-3):194-8.
2012: Martin J Brodie; Patrick Kwan
Newer drugs for focal epilepsy in adults.
BMJ (Clinical research ed.) 2012;344():e345.
2011: Linda J Stephen; Kevin Kelly; Pamela Parker; Martin J Brodie
Levetiracetam monotherapy--outcomes from an epilepsy clinic.
Seizure : the journal of the British Epilepsy Association 2011;20(7):554-7.
2011: Martin J Brodie; Athanasios Covanis; Antonio Gil-Nagel; Holger Lerche; Emilio Perucca; Graeme J Sills; H Steve White
Antiepileptic drug therapy: does mechanism of action matter?
Epilepsy & behavior : E&B 2011;21(4):331-41.
2011: Martin J Brodie; Graeme J Sills
Combining antiepileptic drugs--rational polytherapy?
Seizure : the journal of the British Epilepsy Association 2011;20(5):369-75.
2011: Linda J Stephen; Martin J Brodie
Pharmacotherapy of epilepsy: newly approved and developmental agents.
CNS drugs 2011;25(2):89-107.
2010: Martin J Brodie
Antiepileptic drug therapy the story so far.
Seizure : the journal of the British Epilepsy Association 2010;19(10):650-5.
2010: Martin J Brodie; H Lerche; A Gil-Nagel; C Elger; S Hall; P Shin; V Nohria; H Mansbach
Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy.
Neurology 2010;75(20):1817-24.
2010: Linda J Stephen; Kevin Kelly; Elaine A Wilson; Pamela Parker; Martin J Brodie
A prospective audit of adjunctive zonisamide in an everyday clinical setting.
Epilepsy & behavior : E&B 2010;17(4):455-60.
2009: Linda J Stephen; Martin J Brodie
Selection of antiepileptic drugs in adults.
Neurologic clinics 2009;27(4):967-92.
2009: Pedro Gonzalez; Graeme J Sills; Stuart Parks; Kevin Kelly; Linda J Stephen; David Keating; Gordon N Dutton; Martin J Brodie
Binasal visual field defects are not specific to vigabatrin.
Epilepsy & behavior : E&B 2009;16(3):521-6.
2009: Martin J Brodie; Andrew T Elder; Patrick Kwan
Epilepsy in later life.
Lancet neurology 2009;8(11):1019-30.
2009: Martin J Brodie; William E Rosenfeld; Blanca Vazquez; Rajesh Sachdeo; Carlos Perdomo; Allison Mann; Santiago Arroyo
Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: a randomized placebo-controlled trial.
Epilepsia 2009;50(8):1899-909.
2009: Mohd Makmor-Bakry; Graeme J Sills; Nikolas Hitiris; Elaine Butler; Elaine A Wilson; Martin J Brodie
Genetic variants in microsomal epoxide hydrolase influence carbamazepine dosing.
Clinical neuropharmacology 2009;32(4):205-12.
2009: Cassandra Szoeke; Graeme J Sills; Patrick Kwan; Slave Petrovski; Mark Newton; Nikolas Hitiris; Larry Baum; Samuel F Berkovic; Martin J Brodie; Leslie J Sheffield; Terence J O'Brien
Multidrug-resistant genotype (ABCB1) and seizure recurrence in newly treated epilepsy: data from international pharmacogenetic cohorts.
Epilepsia 2009;50(7):1689-96.
2008: Linda J Stephen; Martin J Brodie
Management of a first seizure. Special problems: adults and elderly.
Epilepsia 2008;49 Suppl 1():45-9.
2007: Nikolas Hitiris; Rajiv Mohanraj; John Norrie; Graeme J Sills; Martin J Brodie
Predictors of pharmacoresistant epilepsy.
Epilepsy research 2007;75(2-3):192-6.
2007: Linda J Stephen; Graeme J Sills; John Paul Leach; Elaine Butler; Pamela Parker; Nikolas Hitiris; Veronica M Leach; Elaine A Wilson; Martin J Brodie
Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy.
Epilepsy research 2007;75(2-3):122-9.
2007: Nikolas Hitiris; Rajiv Mohanraj; John Norrie; Martin J Brodie
Mortality in epilepsy.
Epilepsy & behavior : E&B 2007;10(3):363-76.
2007: Nikolas Hitiris; Suraya Suratman; Kevin Kelly; Linda J Stephen; Graeme J Sills; Martin J Brodie
Sudden unexpected death in epilepsy: a search for risk factors.
Epilepsy & behavior : E&B 2007;10(1):138-41.
2007: Martin J Brodie; Linda J Stephen
Outcomes in elderly patients with newly diagnosed and treated epilepsy.
International review of neurobiology 2007;81():253-63.
2006: John Paul Leach; Linda J Stephen; C Salveta; Martin J Brodie
Which electroencephalography (EEG) for epilepsy? The relative usefulness of different EEG protocols in patients with possible epilepsy.
Journal of neurology, neurosurgery, and psychiatry 2006;77(9):1040-2.
2006: Rajiv Mohanraj; John Norrie; Linda J Stephen; Kevin Kelly; Nikolas Hitiris; Martin J Brodie
Mortality in adults with newly diagnosed and chronic epilepsy: a retrospective comparative study.
Lancet neurology 2006;5(6):481-7.
2006: Nikolas Hitiris; Martin J Brodie
Modern antiepileptic drugs: guidelines and beyond.
Current opinion in neurology 2006;19(2):175-80.
2006: Rajiv Mohanraj; Martin J Brodie
Diagnosing refractory epilepsy: response to sequential treatment schedules.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2006;13(3):277-82.
2006: Nikolas Hitiris; Jeannette A Barrett; Martin J Brodie
Erectile dysfunction associated with pregabalin add-on treatment in patients with partial seizures: five case reports.
Epilepsy & behavior : E&B 2006;8(2):418-21.
2006: Linda J Stephen; Kevin Kelly; Rajiv Mohanraj; Martin J Brodie
Pharmacological outcomes in older people with newly diagnosed epilepsy.
Epilepsy & behavior : E&B 2006;8(2):434-7.
2005: Martin J Brodie; Patrick Kwan
Epilepsy in elderly people.
BMJ (Clinical research ed.) 2005;331(7528):1317-22.
2005: Rajiv Mohanraj; Martin J Brodie
Outcomes in newly diagnosed localization-related epilepsies.
Seizure : the journal of the British Epilepsy Association 2005;14(5):318-23.
2005: Graeme J Sills; Rajiv Mohanraj; Elaine Butler; Sheila McCrindle; Lindsay Collier; Elaine A Wilson; Martin J Brodie
Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.
Epilepsia 2005;46(5):643-7.
2005: Rajiv Mohanraj; Martin J Brodie
Pharmacological outcomes in newly diagnosed epilepsy.
Epilepsy & behavior : E&B 2005;6(3):382-7.
2005: Martin J Brodie
Response to antiepileptic drug therapy: winners and losers.
Epilepsia 2005;46 Suppl 10():31-2.
2005: Nikolas Hitiris; Martin J Brodie
Evidence-based treatment of idiopathic generalized epilepsies with older antiepileptic drugs.
Epilepsia 2005;46 Suppl 9():149-53.
2005: Martin J Brodie; Roderick Duncan; Herve Vespignani; Andras Solyom; Valeriy Bitenskyy; Cherry Lucas
Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures.
Epilepsia 2005;46(1):31-41.
2005: Rajiv Mohanraj; Pamela G Parker; Linda J Stephen; Martin J Brodie
Levetiracetam in refractory epilepsy: a prospective observational study.
Seizure : the journal of the British Epilepsy Association 2005;14(1):23-7.
2004: Kevin Kelly; Linda J Stephen; Martin J Brodie
Levetiracetam for people with mental retardation and refractory epilepsy.
Epilepsy & behavior : E&B 2004;5(6):878-83.
2004: Martin J Brodie
Zonisamide clinical trials: European experience.
Seizure : the journal of the British Epilepsy Association 2004;13 Suppl 1():S66-70; discussion S71-2.
2004: Graeme J Sills; Elaine Butler; George G Thompson; Martin J Brodie
Pharmacodynamic interaction studies with topiramate in the pentylenetetrazol and maximal electroshock seizure models.
Seizure : the journal of the British Epilepsy Association 2004;13(5):287-95.
2004: Kevin Kelly; Linda J Stephen; Martin J Brodie
Pharmacological outcomes in people with mental retardation and epilepsy.
Epilepsy & behavior : E&B 2004;5(1):67-71.
2003: J McDonagh; Linda J Stephen; Fiona M Dolan; Stuart Parks; Gordon N Dutton; K Kelly; David Keating; Graeme J Sills; Martin J Brodie
Peripheral retinal dysfunction in patients taking vigabatrin.
Neurology 2003;61(12):1690-4.
2003: Linda J Stephen; Jan Maxwell; Martin J Brodie
Outcomes from a nurse-led clinic for adolescents with epilepsy.
Seizure : the journal of the British Epilepsy Association 2003;12(8):539-44.
2003: Rajiv Mohanraj; Martin J Brodie
Measuring the efficacy of antiepileptic drugs.
Seizure : the journal of the British Epilepsy Association 2003;12(7):413-43.
2003: Graeme J Sills; Elaine Butler; Gerard Forrest; Neville Ratnaraj; Philip N Patsalos; Martin J Brodie
Vigabatrin, but not gabapentin or topiramate, produces concentration-related effects on enzymes and intermediates of the GABA shunt in rat brain and retina.
Epilepsia 2003;44(7):886-92.
2003: Martin J Brodie; Jacqueline A French
Role of levetiracetam in the treatment of epilepsy.
Epileptic disorders : international epilepsy journal with videotape 2003;5 Suppl 1():S65-72.
2003: Patrick Kwan; Graeme J Sills; Elaine Butler; Timothy W Gant; Martin J Brodie
Differential expression of multidrug resistance genes in naïve rat brain.
Neuroscience letters 2003;339(1):33-6.
2003: Martin J Brodie
Building new understandings in epilepsy: maximizing patient outcomes without sacrificing seizure control.
Epilepsia 2003;44 Suppl 4():1-2.
2002: Patrick Kwan; Graeme J Sills; Elaine Butler; Timothy W Gant; Brian S Meldrum; Martin J Brodie
Regional expression of multidrug resistance genes in genetically epilepsy-prone rat brain after a single audiogenic seizure.
Epilepsia 2002;43(11):1318-23.
2002: Martin J Brodie; David W Chadwick; Henning Anhut; Andreas Otte; Silke-Lo Messmer; Stephen Maton; Wilhelm Sauermann; Guta Murray; Elizabeth A Garofalo
Gabapentin versus lamotrigine monotherapy: a double-blind comparison in newly diagnosed epilepsy.
Epilepsia 2002;43(9):993-1000.
2002: Linda J Stephen; Martin J Brodie
Seizure freedom with more than one antiepileptic drug.
Seizure : the journal of the British Epilepsy Association 2002;11(6):349-51.
2002: Graeme J Sills; Sarah Lynagh; Gerard Forrest; Martin J Brodie
Influence of cytochrome P450 induction on the pharmacokinetics and pharmacodynamics of remacemide hydrochloride.
Epilepsy research 2002;49(3):247-54.
2002: Martin J Brodie; Patrick Kwan
Staged approach to epilepsy management.
Neurology 2002;58(8 Suppl 5):S2-8.
2002: Kevin Kelly; Linda J Stephen; Graeme J Sills; Martin J Brodie
Topiramate in patients with learning disability and refractory epilepsy.
Epilepsia 2002;43(4):399-402.
2002: Sarah Lynagh; Graeme J Sills; Trevor W Stone; Martin J Brodie
Differential effects of remacemide and desglycinyl-remacemide on epileptiform burst firing in the rat hippocampal slice.
Neuroscience letters 2002;321(1-2):33-6.
2002: Sarah Lynagh; Graeme J Sills; George G Thompson; Martin J Brodie
Na(+) channel effects of remacemide and desglycinyl-remacemide in rat cortical synaptosomes.
European journal of pharmacology 2002;438(1-2):63-8.
2001: Graeme J Sills; Martin J Brodie
Update on the mechanisms of action of antiepileptic drugs.
Epileptic disorders : international epilepsy journal with videotape 2001;3(4):165-72.
2001: Patrick Kwan; Martin J Brodie
Effectiveness of first antiepileptic drug.
Epilepsia 2001;42(10):1255-60.
2001: Linda J Stephen; Patrick Kwan; D Shapiro; M Dominiczak; Martin J Brodie
Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.
Epilepsia 2001;42(8):1002-6.
2001: Graeme J Sills; Philip N Patsalos; Elaine Butler; Gerard Forrest; Neville Ratnaraj; Martin J Brodie
Visual field constriction: accumulation of vigabatrin but not tiagabine in the retina.
Neurology 2001;57(2):196-200.
2001: Martin J Brodie
Monotherapy trials: prerequisite data.
Epilepsy research 2001;45(1-3):61-4; discussion 65-6.
2001: Martin J Brodie
Do we need any more new antiepileptic drugs?
Epilepsy research 2001;45(1-3):3-6.
2001: Patrick Kwan; Graeme J Sills; Martin J Brodie
The mechanisms of action of commonly used antiepileptic drugs.
Pharmacology & therapeutics 2001;90(1):21-34.
2001: Linda J Stephen; Patrick Kwan; Martin J Brodie
Does the cause of localisation-related epilepsy influence the response to antiepileptic drug treatment?
Epilepsia 2001;42(3):357-62.
2001: P Kwan; Martin J Brodie
Neuropsychological effects of epilepsy and antiepileptic drugs.
Lancet 2001;357(9251):216-22.
2001: Martin J Brodie
Management strategies for refractory localization-related seizures.
Epilepsia 2001;42 Suppl 3():27-30.
2000: Patrick Kwan; Graeme J Sills; K Kelly; Elaine Butler; Martin J Brodie
Glutamic acid decarboxylase autoantibodies in controlled and uncontrolled epilepsy: a pilot study.
Epilepsy research 2000;42(2-3):191-5.
2000: Graeme J Sills; C Rundfeldt; Elaine Butler; Gerard Forrest; George G Thompson; Martin J Brodie
A neurochemical study of the novel antiepileptic drug retigabine in mouse brain.
Pharmacological research : the official journal of the Italian Pharmacological Society 2000;42(6):553-7.
2000: P Kwan; Martin J Brodie
Epilepsy after the first drug fails: substitution or add-on?
Seizure : the journal of the British Epilepsy Association 2000;9(7):464-8.
2000: Sarah Lynagh; C McNeill; Graeme J Sills; Martin J Brodie
Simultaneous determination of remacemide hydrochloride and desglycinylremacemide (AR-R12495XX) in brain tissue by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 2000;746(2):325-9.
2000: Linda J Stephen; Graeme J Sills; Martin J Brodie
Topiramate in refractory epilepsy: a prospective observational study.
Epilepsia 2000;41(8):977-80.
2000: Martin J Brodie; J A French
Management of epilepsy in adolescents and adults.
Lancet 2000;356(9226):323-9.
2000: Linda J Stephen; Martin J Brodie
Epilepsy in elderly people.
Lancet 2000;355(9213):1441-6.
2000: Graeme J Sills; John Paul Leach; W S Kilpatrick; CM Fraser; George G Thompson; Martin J Brodie
Concentration-effect studies with topiramate on selected enzymes and intermediates of the GABA shunt.
Epilepsia 2000;41 Suppl 1():S30-4.
1999: Graeme J Sills; Elaine Butler; George G Thompson; Martin J Brodie
Vigabatrin and tiagabine are pharmacologically different drugs. A pre-clinical study.
Seizure : the journal of the British Epilepsy Association 1999;8(7):404-11.
1999: CM Fraser; Graeme J Sills; Elaine Butler; George G Thompson; K Lindsay; R Duncan; A Howatson; Martin J Brodie
Effects of valproate, vigabatrin and tiagabine on GABA uptake into human astrocytes cultured from foetal and adult brain tissue.
Epileptic disorders : international epilepsy journal with videotape 1999;1(3):153-7.
1999: Linda J Stephen; A R McLellan; J H Harrison; D Shapiro; Marek Dominiczak; Graeme J Sills; Martin J Brodie
Bone density and antiepileptic drugs: a case-controlled study.
Seizure : the journal of the British Epilepsy Association 1999;8(6):339-42.
1999: CM Fraser; Graeme J Sills; Gerard Forrest; George G Thompson; Martin J Brodie
Neurochemical studies with the anticonvulsant felbamate in mouse brain.
Pharmacological research : the official journal of the Italian Pharmacological Society 1999;40(3):257-61.
1999: CM Fraser; Graeme J Sills; Gerard Forrest; George G Thompson; Martin J Brodie
Effects of anti-epileptic drugs on glutamine synthetase activity in mouse brain.
British journal of pharmacology 1999;126(7):1634-8.
1999: L J Stephen; J E Maxwell; Martin J Brodie
Transient hemiparesis with topiramate.
BMJ (Clinical research ed.) 1999;318(7187):845.
1999: Martin J Brodie
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Epilepsia 1999;40 Suppl 6():S17-22; discussion S73-4.
1998: Linda J Stephen; Martin J Brodie
An islander with seizures.
Scottish medical journal 1998;43(6):183-4.
1998: C L Read; Linda J Stephen; I H Stolarek; A Paul; Graeme J Sills; Martin J Brodie
Cognitive effects of anticonvulsant monotherapy in elderly patients: a placebo-controlled study.
Seizure : the journal of the British Epilepsy Association 1998;7(2):159-62.
1998: J A Hannah; Martin J Brodie
Treatment of seizures in patients with learning disabilities.
Pharmacology & therapeutics 1998;78(1):1-8.
1998: Linda J Stephen; Graeme J Sills; Martin J Brodie
Lamotrigine and topiramate may be a useful combination.
Lancet 1998;351(9107):958-9.
1998: J A Hannah; Martin J Brodie
Epilepsy and learning disabilities--a challenge for the next millennium?
Seizure : the journal of the British Epilepsy Association 1998;7(1):3-13.
1998: John Paul Leach; Martin J Brodie
Tiagabine.
Lancet 1998;351(9097):203-7.
1998: Elaine A Wilson; Graeme J Sills; Gerard Forrest; Martin J Brodie
High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients.
Epilepsy research 1998;29(2):161-6.
1997: John Paul Leach; Graeme J Sills; Elaine Butler; Gerard Forrest; George G Thompson; Martin J Brodie
Neurochemical actions of the desglycinyl metabolite of remacemide hydrochloride (ARL 12495AA) in mouse brain.
British journal of pharmacology 1997;121(5):923-6.
1997: John Paul Leach; Graeme J Sills; Elaine Butler; Gerard Forrest; George G Thompson; Martin J Brodie
Neurochemical actions of gabapentin in mouse brain.
Epilepsy research 1997;27(3):175-80.
1997: John Paul Leach; J Girvan; V Jamieson; T Jones; A Richens; Martin J Brodie
Lack of pharmacokinetic interaction between remacemide hydrochloride and sodium valproate in epileptic patients.
Seizure : the journal of the British Epilepsy Association 1997;6(3):179-84.
1997: Martin J Brodie; M A Dichter
Established antiepileptic drugs.
Seizure : the journal of the British Epilepsy Association 1997;6(3):159-74.
1997: John Paul Leach; Graeme J Sills; Elaine Butler; Gerard Forrest; George G Thompson; Martin J Brodie
Neurochemical actions of vigabatrin and tiagabine alone and in combination in mouse cortex.
General pharmacology 1997;28(5):715-9.
1997: Graeme J Sills; John Paul Leach; CM Fraser; Gerard Forrest; Philip N Patsalos; Martin J Brodie
Neurochemical studies with the novel anticonvulsant levetiracetam in mouse brain.
European journal of pharmacology 1997;325(1):35-40.
1997: John Paul Leach; J Girvan; A Paul; Martin J Brodie
Gabapentin and cognition: a double blind, dose ranging, placebo controlled study in refractory epilepsy.
Journal of neurology, neurosurgery, and psychiatry 1997;62(4):372-6.
1997: Martin J Brodie; A W Yuen
Lamotrigine substitution study: evidence for synergism with sodium valproate? 105 Study Group.
Epilepsy research 1997;26(3):423-32.
1997: John Paul Leach; J Girvan; V Jamieson; T Jones; A Richens; Martin J Brodie
Mutual interaction between remacemide hydrochloride and phenytoin.
Epilepsy research 1997;26(2):381-8.