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Jeffrey Brodsky

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Chemicals & Drugs

Living Beings

Saccharomyces cerevisiae

Physiology

Concepts & Ideas

Tertiary Protein Structure

Phenomena

Protein Binding

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Network (preview)

Co-Publications
Name
16
McCracken, Ardythe
13
Fewell, Sheara
7
Goeckeler, Jennifer
7
Pipas, James
6
Fisher, Edward
6
Kruse, Kristina
5
Gusarova, Viktoria
5
Chiosis, Gabriela
5
Wipf, Peter
5
Zeidel, Mark
4
Watkins, Simon
4
Sullivan, Mara
4
Caplan, Avrom
4
Ahner, Annette
4
Coughlan, Christina

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Publications

TOP 3
Vembar Shruthi S; Jin Yi; Brodsky Jeffrey L; Hendershot Linda M
The mammalian Hsp40 ERdj3 requires its Hsp70 interaction and substrate-binding properties to complement various yeast Hsp40-dependent functions.
Brodsky Jeffrey L; Wojcikiewicz Richard J H
Substrate-specific mediators of ER associated degradation (ERAD).
Haney Conor M; Schneider Corinne; Beck Barbara; Brodsky Jeffrey L; Dömling Alexander
Identification of Hsp70 modulators through modeling of the substrate binding domain.

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All Publications

2009: Vembar Shruthi S; Jin Yi; Brodsky Jeffrey L; Hendershot Linda M
The mammalian Hsp40 ERdj3 requires its Hsp70 interaction and substrate-binding properties to complement various yeast Hsp40-dependent functions.
The Journal of biological chemistry 2009;284(47):32462-71.
2009: Brodsky Jeffrey L; Wojcikiewicz Richard J H
Substrate-specific mediators of ER associated degradation (ERAD).
Current opinion in cell biology 2009;21(4):516-21.
2009: Haney Conor M; Schneider Corinne; Beck Barbara; Brodsky Jeffrey L; Dömling Alexander
Identification of Hsp70 modulators through modeling of the substrate binding domain.
Bioorganic & medicinal chemistry letters 2009;19(14):3828-31.
2009: Park Hyun-Joo; Mylvaganum Murugesapillai; McPherson Anne; Fewell Sheara W; Brodsky Jeffrey L; Lingwood Clifford A
A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation.
Chemistry & biology 2009;16(4):461-70.
2009: Wright Christine M; Seguin Sandlin P; Fewell Sheara W; Zhang Haijiang; Ishwad Chandra; Vats Abhay; Lingwood Clifford A; Wipf Peter; Fanning Ellen; Pipas James M; Brodsky Jeffrey L
Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.
Virus research 2009;141(1):71-80.
2009: Patham Bhargavi; Duffy Josh; Lane Ariel; Davis Richard C; Wipf Peter; Fewell Sheara W; Brodsky Jeffrey L; Mensa-Wilmot Kojo
Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.
The Biochemical journal 2009;419(2):507-17.
2009: Chiang Annette N; Valderramos Juan-Carlos; Balachandran Raghavan; Chovatiya Raj J; Mead Brian P; Schneider Corinne; Bell Samantha L; Klein Michael G; Huryn Donna M; Chen Xiaojiang S; Day Billy W; Fidock David A; Wipf Peter; Brodsky Jeffrey L
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum.
Bioorganic & medicinal chemistry 2009;17(4):1527-33.
2008: Vembar Shruthi S; Brodsky Jeffrey L
One step at a time: endoplasmic reticulum-associated degradation.
Nature reviews. Molecular cell biology 2008;9(12):944-57.
2008: Brodsky Jeffrey L; Fisher Edward A
The many intersecting pathways underlying apolipoprotein B secretion and degradation.
Trends in endocrinology and metabolism: TEM 2008;19(7):254-9.
2008: Goeckeler Jennifer L; Petruso Anthony P; Aguirre Julia; Clement Cristina C; Chiosis Gabriela; Brodsky Jeffrey L
The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding.
FEBS letters 2008;582(16):2393-6.
2008: Kang Yanlong; Taldone Tony; Clement Cristina C; Fewell Sheara W; Aguirre Julia; Brodsky Jeffrey L; Chiosis Gabriela
Design of a fluorescence polarization assay platform for the study of human Hsp70.
Bioorganic & medicinal chemistry letters 2008;18(13):3749-51.
2008: Nakatsukasa Kunio; Brodsky Jeffrey L
The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum.
Traffic (Copenhagen, Denmark) 2008;9(6):861-70.
2008: Wright Christine M; Chovatiya Raj J; Jameson Nora E; Turner David M; Zhu Guangyu; Werner Stefan; Huryn Donna M; Pipas James M; Day Billy W; Wipf Peter; Brodsky Jeffrey L
Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation.
Bioorganic & medicinal chemistry 2008;16(6):3291-301.
2008: Nakatsukasa Kunio; Huyer Gregory; Michaelis Susan; Brodsky Jeffrey L
Dissecting the ER-associated degradation of a misfolded polytopic membrane protein.
Cell 2008;132(1):101-12.
2007: Buck Teresa M; Wright Christine M; Brodsky Jeffrey L
The activities and function of molecular chaperones in the endoplasmic reticulum.
Seminars in cell & developmental biology 2007;18(6):751-61.
2007: Sparvero Louis J; Patz Sarah; Brodsky Jeffrey L; Coughlan Christina M
Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast.
Analytical biochemistry 2007;370(2):162-70.
2007: Hrizo Stacy L; Gusarova Viktoria; Habiel David M; Goeckeler Jennifer L; Fisher Edward A; Brodsky Jeffrey L
The Hsp110 molecular chaperone stabilizes apolipoprotein B from endoplasmic reticulum-associated degradation (ERAD).
The Journal of biological chemistry 2007;282(45):32665-75.
2007: Brodsky Jeffrey L; Scott Craig M
Tipping the delicate balance: defining how proteasome maturation affects the degradation of a substrate for autophagy and endoplasmic reticulum associated degradation (ERAD).
Autophagy 2007;3(6):623-5.
2007: Feng Dejiang; Zhao Xueqiang; Soromani Christina; Toikkanen Jaana; Römisch Karin; Vembar Shruthi S; Brodsky Jeffrey L; Keränen Sirkka; Jäntti Jussi
The transmembrane domain is sufficient for Sbh1p function, its association with the Sec61 complex, and interaction with Rtn1p.
The Journal of biological chemistry 2007;282(42):30618-28.
2007: Scott Craig M; Kruse Kristina B; Schmidt Béla Z; Perlmutter David H; McCracken Ardythe A; Brodsky Jeffrey L
ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.
Molecular biology of the cell 2007;18(10):3776-87.
2007: Kashlan Ossama B; Mueller Gunhild M; Qamar Mohammad Z; Poland Paul A; Ahner Annette; Rubenstein Ronald C; Hughey Rebecca P; Brodsky Jeffrey L; Kleyman Thomas R
Small heat shock protein alphaA-crystallin regulates epithelial sodium channel expression.
The Journal of biological chemistry 2007;282(38):28149-56.
2007: Rodina Anna; Vilenchik Maria; Moulick Kamalika; Aguirre Julia; Kim Joungnam; Chiang Anne; Litz Julie; Clement Cristina C; Kang Yanlong; She Yuhong; Wu Nian; Felts Sara; Wipf Peter; Massague Joan; Jiang Xuejun; Brodsky Jeffrey L; Krystal Geoffrey W; Chiosis Gabriela
Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.
Nature chemical biology 2007;3(8):498-507.
2007: Gusarova Viktoria; Seo Jeongmin; Sullivan Mara L; Watkins Simon C; Brodsky Jeffrey L; Fisher Edward A
Golgi-associated maturation of very low density lipoproteins involves conformational changes in apolipoprotein B, but is not dependent on apolipoprotein E.
The Journal of biological chemistry 2007;282(27):19453-62.
2007: Brodsky Jeffrey L
The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation).
The Biochemical journal 2007;404(3):353-63.
2007: Perlmutter David H; Brodsky Jeffrey L; Balistreri William F; Trapnell Bruce C
Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review.
Hepatology (Baltimore, Md.) 2007;45(5):1313-23.
2007: Wright Christine M; Fewell Sheara W; Sullivan Mara L; Pipas James M; Watkins Simon C; Brodsky Jeffrey L
The Hsp40 molecular chaperone Ydj1p, along with the protein kinase C pathway, affects cell-wall integrity in the yeast Saccharomyces cerevisiae.
Genetics 2007;175(4):1649-64.
2007: Ahner Annette; Nakatsukasa Kunio; Zhang Hui; Frizzell Raymond A; Brodsky Jeffrey L
Small heat-shock proteins select deltaF508-CFTR for endoplasmic reticulum-associated degradation.
Molecular biology of the cell 2007;18(3):806-14.
2007: Mandal Atin K; Lee Paul; Chen Jennifer A; Nillegoda Nadinath; Heller Alana; DiStasio Susan; Oen Handy; Victor Jacob; Nair Devi M; Brodsky Jeffrey L; Caplan Avrom J
Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation.
The Journal of cell biology 2007;176(3):319-28.
2006: Kruse Kristina B; Brodsky Jeffrey L; McCracken Ardythe A
Autophagy: an ER protein quality control process.
Autophagy 2006;2(2):135-7.
2006: Zhang Hui; Schmidt Bela Z; Sun Fei; Condliffe Steven B; Butterworth Michael B; Youker Robert T; Brodsky Jeffrey L; Aridor Meir; Frizzell Raymond A
Cysteine string protein monitors late steps in cystic fibrosis transmembrane conductance regulator biogenesis.
The Journal of biological chemistry 2006;281(16):11312-21.
2006: Kruse Kristina B; Brodsky Jeffrey L; McCracken Ardythe A
Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ.
Molecular biology of the cell 2006;17(1):203-12.
2006: Brodsky Jeffrey L; Chiosis Gabriela
Hsp70 molecular chaperones: emerging roles in human disease and identification of small molecule modulators.
Current topics in medicinal chemistry 2006;6(11):1215-25.
2005: Kaufmann Nancy; Mathai John C; Hill Warren G; Dow Julian A T; Zeidel Mark L; Brodsky Jeffrey L
Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin.
American journal of physiology. Cell physiology 2005;289(2):C397-407.
2005: Chiosis Gabriela; Brodsky Jeffrey L
Small molecule microarrays: from proteins to mammalian cells - are we there yet?
Trends in biotechnology 2005;23(6):271-4.
2005: Coughlan Christina M; Brodsky Jeffrey L
Use of yeast as a model system to investigate protein conformational diseases.
Molecular biotechnology 2005;30(2):171-80.
2005: Nishikawa Shuh-ichi; Brodsky Jeffrey L; Nakatsukasa Kunio
Roles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD).
Journal of biochemistry 2005;137(5):551-5.
2005: Brodsky Jeffrey L
An in vitro assay for the selective endoplasmic reticulum associated degradation of an unglycosylated secreted protein.
Methods (San Diego, Calif.) 2005;35(4):354-9.
2005: Ahner Annette; Whyte Fadra M; Brodsky Jeffrey L
Distinct but overlapping functions of Hsp70, Hsp90, and an Hsp70 nucleotide exchange factor during protein biogenesis in yeast.
Archives of biochemistry and biophysics 2005;435(1):32-41.
2005: Shomura Yasuhito; Dragovic Zdravko; Chang Hung-Chun; Tzvetkov Nikolay; Young Jason C; Brodsky Jeffrey L; Guerriero Vince; Hartl F Ulrich; Bracher Andreas
Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange.
Molecular cell 2005;17(3):367-79.
2005: Karlgren Sara; Pettersson Nina; Nordlander Bodil; Mathai John C; Brodsky Jeffrey L; Zeidel Mark L; Bill Roslyn M; Hohmann Stefan
Conditional osmotic stress in yeast: a system to study transport through aquaglyceroporins and osmostress signaling.
The Journal of biological chemistry 2005;280(8):7186-93.
2005: McCracken A A; Brodsky J L
Recognition and delivery of ERAD substrates to the proteasome and alternative paths for cell survival.
Current topics in microbiology and immunology 2005;300():17-40.
2005: Lee Robert J; McCracken Ardythe A; Brodsky Jeffrey L
Reconstitution of endoplasmic reticulum-associated degradation using yeast membranes and cytosol.
Methods in molecular biology (Clifton, N.J.) 2005;301():175-84.
2004: Fewell Sheara W; Smith Christine M; Lyon Michael A; Dumitrescu Teodora Pene; Wipf Peter; Day Billy W; Brodsky Jeffrey L
Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.
The Journal of biological chemistry 2004;279(49):51131-40.
2004: Youker Robert T; Walsh Peter; Beilharz Traude; Lithgow Trevor; Brodsky Jeffrey L
Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast.
Molecular biology of the cell 2004;15(11):4787-97.
2004: Ahner Annette; Brodsky Jeffrey L
Checkpoints in ER-associated degradation: excuse me, which way to the proteasome?
Trends in cell biology 2004;14(9):474-8.
2004: Lee Robert J; Liu Chang-Wei; Harty Carol; McCracken Ardythe A; Latterich Martin; Römisch Karin; DeMartino George N; Thomas Philip J; Brodsky Jeffrey L
Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein.
The EMBO journal 2004;23(11):2206-15.
2004: Brodsky Jeffrey L; Gusarova Viktoria; Fisher Edward A
Vesicular trafficking of hepatic apolipoprotein B100 and its maturation to very low-density lipoprotein particles; studies from cells and cell-free systems.
Trends in cardiovascular medicine 2004;14(4):127-32.
2004: Shaner Lance; Trott Amy; Goeckeler Jennifer L; Brodsky Jeffrey L; Morano Kevin A
The function of the yeast molecular chaperone Sse1 is mechanistically distinct from the closely related hsp70 family.
The Journal of biological chemistry 2004;279(21):21992-2001.
2004: Coughlan Christina M; Walker Jennifer L; Cochran Jared C; Wittrup K Dane; Brodsky Jeffrey L
Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control.
The Journal of biological chemistry 2004;279(15):15289-97.
2003: Gusarova Viktoria; Brodsky Jeffrey L; Fisher Edward A
Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER.
The Journal of biological chemistry 2003;278(48):48051-8.
2003: McCracken Ardythe A; Brodsky Jeffrey L
Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).
BioEssays : news and reviews in molecular, cellular and developmental biology 2003;25(9):868-77.
2003: Kabani Mehdi; Kelley Stephanie S; Morrow Michael W; Montgomery Diana L; Sivendran Renuka; Rose Mark D; Gierasch Lila M; Brodsky Jeffrey L
Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP.
Molecular biology of the cell 2003;14(8):3437-48.
2003: Palmer Elizabeth A; Kruse Kristina B; Fewell Sheara W; Buchanan Sean M; Brodsky Jeffrey L; McCracken Ardythe A
Differential requirements of novel A1PiZ degradation deficient (ADD) genes in ER-associated protein degradation.
Journal of cell science 2003;116(Pt 11):2361-73.
2003: Sullivan Mara L; Youker Robert T; Watkins Simon C; Brodsky Jeffrey L
Localization of the BiP molecular chaperone with respect to endoplasmic reticulum foci containing the cystic fibrosis transmembrane conductance regulator in yeast.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(4):545-8.
2003: Coughlan Christina M; Brodsky Jeffrey L
Yeast as a model system to investigate protein conformational diseases.
Methods in molecular biology (Clifton, N.J.) 2003;232():77-90.
2002: Kabani Mehdi; McLellan Catherine; Raynes Deborah A; Guerriero Vince; Brodsky Jeffrey L
HspBP1, a homologue of the yeast Fes1 and Sls1 proteins, is an Hsc70 nucleotide exchange factor.
FEBS letters 2002;531(2):339-42.
2002: Goeckeler Jennifer L; Stephens Andi; Lee Paul; Caplan Avrom J; Brodsky Jeffrey L
Overexpression of yeast Hsp110 homolog Sse1p suppresses ydj1-151 thermosensitivity and restores Hsp90-dependent activity.
Molecular biology of the cell 2002;13(8):2760-70.
2002: Kabani Mehdi; Beckerich Jean-Marie; Brodsky Jeffrey L
Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p.
Molecular and cellular biology 2002;22(13):4677-89.
2002: Fewell Sheara W; Markle Dena M; Brodsky Jeffrey L
The carboxy terminus of simian virus 40 large T antigen is required to disrupt the yeast cell cycle.
Journal of virology 2002;76(9):4621-4.
2002: Fewell Sheara W; Pipas James M; Brodsky Jeffrey L
Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2002-7.
2002: Zhang Yimao; Michaelis Susan; Brodsky Jeffrey L
CFTR expression and ER-associated degradation in yeast.
Methods in molecular medicine 2002;70():257-65.
2001: Gusarova V; Caplan A J; Brodsky J L; Fisher E A
Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70.
The Journal of biological chemistry 2001;276(27):24891-900.
2001: Nishikawa S I; Fewell S W; Kato Y; Brodsky J L; Endo T
Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation.
The Journal of cell biology 2001;153(5):1061-70.
2001: Zhang Y; Nijbroek G; Sullivan M L; McCracken A A; Watkins S C; Michaelis S; Brodsky J L
Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast.
Molecular biology of the cell 2001;12(5):1303-14.
2001: Fewell S W; Day B W; Brodsky J L
Identification of an inhibitor of hsc70-mediated protein translocation and ATP hydrolysis.
The Journal of biological chemistry 2001;276(2):910-4.
2001: Fewell S W; Travers K J; Weissman J S; Brodsky J L
The action of molecular chaperones in the early secretory pathway.
Annual review of genetics 2001;35():149-91.
2000: McClellan A J; Brodsky J L
Mutation of the ATP-binding pocket of SSA1 indicates that a functional interaction between Ssa1p and Ydj1p is required for post-translational translocation into the yeast endoplasmic reticulum.
Genetics 2000;156(2):501-12.
2000: Sullivan C S; Tremblay J D; Fewell S W; Lewis J A; Brodsky J L; Pipas J M
Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40.
Molecular and cellular biology 2000;20(15):5749-57.
2000: McCracken A A; Werner E D; Powell M J; Kruse K B; Brodsky J L
Differential fates of invertase mutants in the yeast endoplasmic reticulum.
Yeast (Chichester, England) 2000;16(1):49-55.
2000: McCracken A A; Brodsky J L
A molecular portrait of the response to unfolded proteins.
Genome biology 2000;1(2):REVIEWS1013.
1999: Brodsky J L; McCracken A A
ER protein quality control and proteasome-mediated protein degradation.
Seminars in cell & developmental biology 1999;10(5):507-13.
1999: Coury L A; McGeoch J E; Guidotti G; Brodsky J L
The yeast Saccharomyces cerevisiae does not sequester chloride but can express a functional mammalian chloride channel.
FEMS microbiology letters 1999;179(2):327-32.
1999: Coury L A; Hiller M; Mathai J C; Jones E W; Zeidel M L; Brodsky J L
Water transport across yeast vacuolar and plasma membrane-targeted secretory vesicles occurs by passive diffusion.
Journal of bacteriology 1999;181(14):4437-40.
1999: Brodsky J L
Selectivity of the molecular chaperone-specific immunosuppressive agent 15-deoxyspergualin: modulation of Hsc70 ATPase activity without compromising DnaJ chaperone interactions.
Biochemical pharmacology 1999;57(8):877-80.
1999: Trimbur G M; Goeckeler J L; Brodsky J L; Walsh C J
Cloning, sequencing, and nucleolar targeting of the basal-body-binding nucleolar protein BN46/51.
Journal of cell science 1999;112 ( Pt 8)():1159-68.
1999: Brodsky J L; Werner E D; Dubas M E; Goeckeler J L; Kruse K B; McCracken A A
The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct.
The Journal of biological chemistry 1999;274(6):3453-60.
1999: Coury L A; Zeidel M L; Brodsky J L
Use of yeast sec6 mutant for purification of vesicles containing recombinant membrane proteins.
Methods in enzymology 1999;306():169-86.
1998: Brodsky J L; Lawrence J G; Caplan A J
Mutations in the cytosolic DnaJ homologue, YDJ1, delay and compromise the efficient translation of heterologous proteins in yeast.
Biochemistry 1998;37(51):18045-55.
1998: McClellan A J; Endres J B; Vogel J P; Palazzi D; Rose M D; Brodsky J L
Specific molecular chaperone interactions and an ATP-dependent conformational change are required during posttranslational protein translocation into the yeast ER.
Molecular biology of the cell 1998;9(12):3533-45.
1998: Brodsky J L; Bäuerle M; Horst M; McClellan A J
Mitochondrial Hsp70 cannot replace BiP in driving protein translocation into the yeast endoplasmic reticulum.
FEBS letters 1998;435(2-3):183-6.
1998: Brodsky J L; Pipas J M
Polyomavirus T antigens: molecular chaperones for multiprotein complexes.
Journal of virology 1998;72(7):5329-34.
1998: Coury L A; Mathai J C; Prasad G V; Brodsky J L; Agre P; Zeidel M L
Reconstitution of water channel function of aquaporins 1 and 2 by expression in yeast secretory vesicles.
The American journal of physiology 1998;274(1 Pt 2):F34-42.
1998: Brodsky J L
Translocation of proteins across the endoplasmic reticulum membrane.
International review of cytology 1998;178():277-328.
1997: Srinivasan A; McClellan A J; Vartikar J; Marks I; Cantalupo P; Li Y; Whyte P; Rundell K; Brodsky J L; Pipas J M
The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.
Molecular and cellular biology 1997;17(8):4761-73.
1997: Brodsky J L; McCracken A A
ER-associated and proteasomemediated protein degradation: how two topologically restricted events came together.
Trends in cell biology 1997;7(4):151-6.
1997: Brodsky J L
Quantitation of membrane proteins in reconstituted vesicles prepared from yeast.
Analytical biochemistry 1997;246(2):262-3.
1996: Werner E D; Brodsky J L; McCracken A A
Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):13797-801.
1996: Brodsky J L
Post-translational protein translocation: not all hsc70s are created equal.
Trends in biochemical sciences 1996;21(4):122-6.
1996: McCracken A A; Brodsky J L
Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.
The Journal of cell biology 1996;132(3):291-8.
1995: Brodsky J L; Goeckeler J; Schekman R
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9643-6.
1990: Brodsky J L; Guidotti G
Hydrolytic properties of the (Na+ + K+)-ATPase isozymes for beta-(2-furyl)acryloyl phosphate, a pseudosubstrate for the sodium pump.
Biochemical and biophysical research communications 1990;172(3):1055-9.
1990: Brodsky J L
Characterization of the (Na+ (+) K+)-ATPase from 3T3-F442A fibroblasts and adipocytes. Isozymes and insulin sensitivity.
The Journal of biological chemistry 1990;265(18):10458-65.
1990: Brodsky J L
Insulin activation of brain Na(+)-K(+)-ATPase is mediated by alpha 2-form of enzyme.
The American journal of physiology 1990;258(5 Pt 1):C812-7.
1990: Brodsky J L; Guidotti G
Sodium affinity of brain Na(+)-K(+)-ATPase is dependent on isozyme and environment of the pump.
The American journal of physiology 1990;258(5 Pt 1):C803-11.
1988: Bhattacharyya M V; Brodsky J L
Characterization of the glucose transporter from rat brain synaptosomes.
Biochemical and biophysical research communications 1988;155(2):685-91.

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