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Shyng-Shiou Yuan

Research Profile

Physiology

Disorders

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Tumor Cell Line

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Publications

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Steven Lo; Shyng-Shiou F Yuan; Ya-Fang Chang; Yu-Jen Cheng; Chin Hsu; Hsiang-Wei Hsueh; Po-Huang Lee; Ya-Ching Hsieh
Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.
Shyng-Shiou F Yuan; Yun-Ju Chen; Ming-Feng Hou; Ya-Ching Hsieh; Chien-Yiu Huang; Yi-Chen Lee; Steven Lo
Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer.
Yun-Ju Chen; Chao-Ming Hung; Ying-Hsien Kao; Nari Kay; Chin-Chen Chen; Shyng-Shiou F Yuan
Progesterone receptor is involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin-stimulated breast cancer cells proliferation.

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2013: Steven Lo; Shyng-Shiou F Yuan; Ya-Fang Chang; Yu-Jen Cheng; Chin Hsu; Hsiang-Wei Hsueh; Po-Huang Lee; Ya-Ching Hsieh
Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.
Annals of surgery 2013;257(2):352-63.
2012: Shyng-Shiou F Yuan; Yun-Ju Chen; Ming-Feng Hou; Ya-Ching Hsieh; Chien-Yiu Huang; Yi-Chen Lee; Steven Lo
Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer.
Journal of the National Cancer Institute 2012;104(19):1485-502.
2012: Yun-Ju Chen; Chao-Ming Hung; Ying-Hsien Kao; Nari Kay; Chin-Chen Chen; Shyng-Shiou F Yuan
Progesterone receptor is involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin-stimulated breast cancer cells proliferation.
Cancer letters 2012;319(2):223-31.
2012: Yi-Chen Lee; Steven Lo; Chun-Chieh Wu; Yun-Ju Chen; Ming-Feng Hou; Shyng-Shiou F Yuan
Resistin expression in breast cancer tissue as a marker of prognosis and hormone therapy stratification.
Gynecologic oncology 2012;125(3):742-50.
2011: Yi-Chen Lee; Jinu-Huang Su; Yi-Hsin Yang; Hsueh-Ling Chang; Ming-Feng Hou; Shyng-Shiou F Yuan
High visfatin expression in breast cancer tissue is associated with poor survival.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(9):1892-901.
2011: Huei-Mei Chen; Fang-Rong Chang; Ya-Ching Hsieh; Yu-Jen Cheng; Kun-Chou Hsieh; Lih-Min Tsai; An-Shen Lin; Yang-Chang Wu; Shyng-Shiou F Yuan
A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species.
Free radical biology & medicine 2011;50(9):1151-62.
2010: Huajun Zhao; Fu Ou-Yang; I-Fen Chen; Ming-Feng Hou; Shyng-Shiou F Yuan; Hsueh-Ling Chang; Yi-Chen Lee; Rina Plattner; Susan E Waltz; Shuk-Mei Ho; Jonathan Sims; Shao-Chun Wang
Enhanced resistance to tamoxifen by the c-ABL proto-oncogene in breast cancer.
Neoplasia (New York, N.Y.) 2010;12(3):214-23.
2009: Huei-Mei Chen; Yang-Chang Wu; Yi-Chen Chia; Fang-Rong Chang; Hseng-Kuang Hsu; Ya-Ching Hsieh; Chih-Chen Chen; Shyng-Shiou F Yuan
Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells.
Cancer letters 2009;286(2):161-71.
2008: Hsueh-Ling Chang; Jinu-Huang Su; Yao-Tsung Yeh; Yi-Chen Lee; Huey-May Chen; Yang-Chang Wu; Shyng-Shiou F Yuan
Protoapigenone, a novel flavonoid, inhibits ovarian cancer cell growth in vitro and in vivo.
Cancer letters 2008;267(1):85-95.
2008: Hsueh-Ling Chang; Yang-Chang Wu; Jinu-Huang Su; Yao-Tsung Yeh; Shyng-Shiou F Yuan
Protoapigenone, a novel flavonoid, induces apoptosis in human prostate cancer cells through activation of p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase 1/2.
The Journal of pharmacology and experimental therapeutics 2008;325(3):841-9.
2007: Yao-Tsung Yeh; Fu Ou-Yang; I-Fen Chen; Sheau-Fang Yang; Jinu-Huang Su; Ming-Feng Hou; Shyng-Shiou F Yuan
Altered p-JAK1 expression is associated with estrogen receptor status in breast infiltrating ductal carcinoma.
Oncology reports 2007;17(1):35-9.
2006: deng-chyang wu; I-Chen Wu; Sheng-Wen Wang; Chien-Yu Lu; Hung-Lung Ke; Shyng-Shiou F Yuan; Yuan-Yung Wang; Wen-Hsiung Chang; Tsang-En Wang; Ming-Jong Bair; Fu-Chen Kuo
Comparison of stool enzyme immunoassay and immunochromatographic method for detecting Helicobacter pylori antigens before and after eradication.
Diagnostic microbiology and infectious disease 2006;56(4):373-8.
2006: Sheau-Fang Yang; Shyng-Shiou F Yuan; Yao-Tsung Yeh; Sz-Chi Hung; Ming-Tsang Wu; Jinu-Huang Su; Chee-Yin Chai
Positive association between STAT3 and Ki-67 in cervical intraepithelial neoplasia.
The Kaohsiung journal of medical sciences 2006;22(11):539-46.
2006: Hsueh-Ling Chang; Hseng-Kuang Hsu; Jinu-Huang Su; Pei-Hui Wang; Yueh-Fang Chung; Yi-Chen Chia; Li-Yu Tsai; Yang-Chang Wu; Shyng-Shiou F Yuan
The fractionated Toona sinensis leaf extract induces apoptosis of human ovarian cancer cells and inhibits tumor growth in a murine xenograft model.
Gynecologic oncology 2006;102(2):309-14.
2006: Yao-Tsung Yeh; Fu Ou-Yang; I-Fen Chen; Sheau-Fang Yang; Yuan-Yung Wang; Hung-Yi Chuang; Jinu-Huang Su; Ming-Feng Hou; Shyng-Shiou F Yuan
STAT3 ser727 phosphorylation and its association with negative estrogen receptor status in breast infiltrating ductal carcinoma.
International journal of cancer. Journal international du cancer 2006;118(12):2943-7.
2006: Da-Chung Chen; Yueh-Fang Chung; Yao-Tsung Yeh; Hso-Chi Chaung; Fu-Chen Kuo; Ou-Yang Fu; Hue-Yong Chen; Ming-Feng Hou; Shyng-Shiou F Yuan
Serum adiponectin and leptin levels in Taiwanese breast cancer patients.
Cancer letters 2006;237(1):109-14.
2006: Yao-Tsung Yeh; Ming-Feng Hou; Yueh-Fang Chung; Yi-Jiun Chen; Sheau-Fang Yang; Da-Chung Chen; Jinu-Huang Su; Shyng-Shiou F Yuan
Decreased expression of phosphorylated JNK in breast infiltrating ductal carcinoma is associated with a better overall survival.
International journal of cancer. Journal international du cancer 2006;118(11):2678-84.
2006: Shyng-Shiou F Yuan; Hsueh-Ling Chang; Hsiao-Wen Chen; Fu-Chen Kuo; Chih-Chuang Liaw; Jinu-Huang Su; Yang-Chang Wu
Selective cytotoxicity of squamocin on T24 bladder cancer cells at the S-phase via a Bax-, Bad-, and caspase-3-related pathways.
Life sciences 2006;78(8):869-74.
2006: Te-Fu Chan; Jinu-Huang Su; Yueh-Fang Chung; Yu-Hsin Hsu; Yao-Tsung Yeh; Shyng-Shiou F Yuan
Elevated amniotic fluid leptin levels in pregnant women who are destined to develop preeclampsia.
Acta obstetricia et gynecologica Scandinavica 2006;85(2):171-4.
2005: Da-Chung Chen; Shyng-Shiou F Yuan; Her-Young Su; Shin-Chieh Lo; Shin-Sia Ren; Gwo-Jang Wu
Urinary cyclic guanosine 3',5'-monophosphate and cyclic adenosine 3',5'-monophosphate changes in spontaneous and induced onset active labor.
Acta obstetricia et gynecologica Scandinavica 2005;84(11):1081-6.
2005: Sheau-Fang Yang; Shyng-Shiou F Yuan; Yao-Tsung Yeh; Ming-Tsang Wu; Jinu-Huang Su; Sz-Chi Hung; Chee-Yin Chai
The role of p-STAT3 (ser727) revealed by its association with Ki-67 in cervical intraepithelial neoplasia.
Gynecologic oncology 2005;98(3):446-52.
2005: Fu-Chen Kuo; deng-chyang wu; Shyng-Shiou F Yuan; Kwo-Ming Hsiao; Yuan-Yung Wang; Yuan-Chieh Yang; Yi-Ching Lo
Effects of arecoline in relaxing human umbilical vessels and inhibiting endothelial cell growth.
Journal of perinatal medicine 2005;33(5):399-405.
2004: Te-Fu Chan; Yueh-Fang Chung; Hung-Sheng Chen; Jinu-Huang Su; Shyng-Shiou F Yuan
Elevated amniotic fluid leptin levels in early second trimester are associated with earlier delivery and lower birthweight in twin pregnancy.
Acta obstetricia et gynecologica Scandinavica 2004;83(8):707-10.
2004: Shyng-Shiou F Yuan; Kun-Bow Tsai; Yueh-Fang Chung; Te-Fu Chan; Yao-Tsung Yeh; Li-Yu Tsai; Jinu-Huang Su
Aberrant expression and possible involvement of the leptin receptor in endometrial cancer.
Gynecologic oncology 2004;92(3):769-75.
2004: Shyng-Shiou F Yuan; Yueh-Fang Chung; Hsiao-Wen Chen; Kun-Bow Tsai; Hsueh-Ling Chang; Chun-Hsiung Huang; Jinu-Huang Su
Aberrant expression and possible involvement of the leptin receptor in bladder cancer.
Urology 2004;63(2):408-13.
2004: Hsiao-Wen Chen; Shyng-Shiou F Yuan; Chi-Jen Lin
Ureteral reimplantation for vesicoureteral reflux: comparison of minimally invasive extravesical with transvesical and conventional extravesical techniques.
Urology 2004;63(2):364-7; discussion 367-8.
2004: Te-Fu Chan; Shyng-Shiou F Yuan; Hung-Sheng Chen; Chen-Feng Guu; Lee-Chen Wu; Yao-Tsung Yeh; Yueh-Fang Chung; Shiang-Bin Jong; Jinu-Huang Su
Correlations between umbilical and maternal serum adiponectin levels and neonatal birthweights.
Acta obstetricia et gynecologica Scandinavica 2004;83(2):165-9.
2004: Hung-Sheng Chen; Te-Fu Chan; Yueh-Fang Chung; Jinu-Huang Su; Shyng-Shiou F Yuan
Aberrant serum adiponectin levels in women with uterine leiomyomas.
Gynecologic and obstetric investigation 2004;58(3):160-3.
2003: Shyng-Shiou F Yuan; Yuan-Kai Yang; Hsiao-Wen Chen; Yueh-Fang Chung; Hsueh-Ling Chang; Jinu-Huang Su
Neocarzinostatin-induced Rad51 nuclear focus formation is cell cycle regulated and aberrant in AT cells.
Toxicology and applied pharmacology 2003;192(3):231-6.
2003: Chih-Chen Chen; Yu-Hsin Hsu; Te-Fu Chan; Shyng-Shiou F Yuan; Jinu-Huang Su
Poor long-term outcome in a survivor presenting with the twin reversed arterial perfusion sequence in utero: a case report.
The Kaohsiung journal of medical sciences 2003;19(10):526-30.
2003: Ming-Feng Hou; Shwu-Bin Lin; Shyng-Shiou F Yuan; Shih-Meng Tsai; Szu Hua Wu; Fu Ou-Yang; Jan-Sing Hsieh; Kun-Bow Tsai; Tsung-Jen Huang; Li-Yu Tsai
The clinical significance between activation of nuclear factor kappa B transcription factor and overexpression of HER-2/neu oncoprotein in Taiwanese patients with breast cancer.
Clinica chimica acta; international journal of clinical chemistry 2003;334(1-2):137-44.
2003: Shyng-Shiou F Yuan; Hsueh-Ling Chang; Hsiao-Wen Chen; Yao-Tsung Yeh; Ying-Hsien Kao; Kuei-Hsiang Lin; Yang-Chang Wu; Jinu-Huang Su
Annonacin, a mono-tetrahydrofuran acetogenin, arrests cancer cells at the G1 phase and causes cytotoxicity in a Bax- and caspase-3-related pathway.
Life sciences 2003;72(25):2853-61.
2003: Te-Fu Chan; Jinu-Huang Su; Yueh-Fang Chung; Yu-Hsin Hsu; Yao-Tsung Yeh; Shiang-Bin Jong; Shyng-Shiou F Yuan
Amniotic fluid and maternal serum leptin levels in pregnant women who subsequently develop preeclampsia.
European journal of obstetrics, gynecology, and reproductive biology 2003;108(1):50-3.
2003: Shyng-Shiou F Yuan; Hsueh-Ling Chang; Eva Y-H P Lee
Ionizing radiation-induced Rad51 nuclear focus formation is cell cycle-regulated and defective in both ATM(-/-) and c-Abl(-/-) cells.
Mutation research 2003;525(1-2):85-92.
2003: Shyng-Shiou F Yuan; Ming-Feng Hou; Hsueh-Ling Chang; Te-Fu Chan; Y H Wu; Yang-Chang Wu; Jinu-Huang Su
Arsenite-induced nitric oxide generation is cell cycle-dependent and aberrant in NBS cells.
Toxicology in vitro : an international journal published in association with BIBRA 2003;17(2):139-43.
2003: Te-Fu Chan; Jinu-Huang Su; Yueh-Fang Chung; Hsueh-Ling Chang; Shyng-Shiou F Yuan
Decreased serum leptin levels in women with uterine leiomyomas.
Acta obstetricia et gynecologica Scandinavica 2003;82(2):173-6.
2003: Ming-Feng Hou; Shwu-Bin Lin; Shyng-Shiou F Yuan; Li-Yu Tsai; Shih-Meng Tsai; Jan-Sing Hsieh; Tsung-Jen Huang
Diagnostic value of urine deoxypyridinoline for detecting bone metastases in breast cancer patients.
Annals of clinical and laboratory science 2003;33(1):55-61.
2003: Ashraf Taha Khalil; Fang-Rong Chang; Yue-Han Lee; Chung-Yi Chen; Chih-Chuang Liaw; Patnam Ramesh; Shyng-Shiou F Yuan; Yang-Chang Wu
Chemical constituents from the Hydrangea chinensis.
Archives of pharmacal research 2003;26(1):15-20.
2002: Yu-Hsin Hsu; Te- Fu Chan; Shyng-Shiou F Yuan; Sheng-Lan Wang; Jinu-Huang Su
Retroperitoneal leiomyomas: a rare tumor of the pelvis.
The Kaohsiung journal of medical sciences 2002;18(12):636-9.
2002: Shyng-Shiou F Yuan; Yao-Tsung Yeh; Eva Y-H P Lee
Pax-2 interacts with RB and reverses its repression on the promoter of Rig-1, a Robo member.
Biochemical and biophysical research communications 2002;296(4):1019-25.
2002: Shyng-Shiou F Yuan; Hsueh-Ling Chang; Ming-Feng Hou; Te-Fu Chan; Ying-Hsien Kao; Yang-Chang Wu; Jinu-Huang Su
Neocarzinostatin induces Mre11 phosphorylation and focus formation through an ATM- and NBS1-dependent mechanism.
Toxicology 2002;177(2-3):123-30.
2002: Shyng-Shiou F Yuan; Jinu-Huang Su; Ming-Feng Hou; Fei-Wen Yang; Song Zhao; Eva Y-H P Lee
Arsenic-induced Mre11 phosphorylation is cell cycle-dependent and defective in NBS cells.
DNA repair 2002;1(2):137-42.