Robert Brodsky

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TOP 3
Emadi Ashkan; Jones Richard J; Brodsky Robert A
Cyclophosphamide and cancer: golden anniversary.
Brodsky Robert A
How I treat paroxysmal nocturnal hemoglobinuria.
Singer Andrew L; Locke Jamye E; Stewart Zoe A; Lonze Bonnie E; Hamilton James P; Scudiere Jennifer R; Anders Robert A; Rother Russell P; Brodsky Robert A; Cameron Andrew M
Successful liver transplantation for Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria treated with the anti-complement antibody eculizumab.

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All Publications

2009: Emadi Ashkan; Jones Richard J; Brodsky Robert A
Cyclophosphamide and cancer: golden anniversary.
Nature reviews. Clinical oncology 2009;6(11):638-47.
2009: Brodsky Robert A
How I treat paroxysmal nocturnal hemoglobinuria.
Blood 2009;113(26):6522-7.
2009: Singer Andrew L; Locke Jamye E; Stewart Zoe A; Lonze Bonnie E; Hamilton James P; Scudiere Jennifer R; Anders Robert A; Rother Russell P; Brodsky Robert A; Cameron Andrew M
Successful liver transplantation for Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria treated with the anti-complement antibody eculizumab.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2009;15(5):540-3.
2009: Hu Rong; Mukhina Galina L; Lee Soo Hee; Jones Richard J; Englund Paul T; Brown Patrick; Sharkis Saul J; Buckley J Thomas; Brodsky Robert A
Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma.
Experimental hematology 2009;37(4):423-434.e2.
2009: Bolaños-Meade J; Luznik L; Muth M; Matsui W H; Huff C A; Smith B D; Levy M Y; Kasamon Y L; Swinnen L J; Powell J D; Brodsky R A; Ambinder R F; Jones R J; Fuchs E J
Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen.
Bone marrow transplantation 2009;43(6):477-80.
2009: Parker Charles J; Brodsky Robert A; Levine John E
Treatment versus transplant for challenging hematologic disorders.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(1 Suppl):72-8.
2009: Savage William J; Barber James P; Mukhina Galina L; Hu Rong; Chen Guibin; Matsui William; Thoburn Chris; Hess Allan D; Cheng Linzhao; Jones Richard J; Brodsky Robert A
Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.
Experimental hematology 2009;37(1):42-51.
2008: Brodsky R A; Luznik L; Bolaños-Meade J; Leffell M S; Jones R J; Fuchs E J
Reduced intensity HLA-haploidentical BMT with post transplantation cyclophosphamide in nonmalignant hematologic diseases.
Bone marrow transplantation 2008;42(8):523-7.
2008: Warlick Erica D; O'Donnell Paul V; Borowitz Michael; Grupka Nichon; Decloe Lauren; Garrett-Mayer Elizabeth; Borrello Ivan; Brodsky Robert; Fuchs Ephraim; Huff Carol Ann; Luznik Leo; Matsui William; Ambinder Richard; Jones Richard J; Douglas Smith B
Myeloablative allogeneic bone marrow transplant using T cell depleted allografts followed by post-transplant GM-CSF in high-risk myelodysplastic syndromes.
Leukemia research 2008;32(9):1439-47.
2008: Krishnan Chitra; Kaplin Adam I; Brodsky Robert A; Drachman Daniel B; Jones Richard J; Pham Dzung L; Richert Nancy D; Pardo Carlos A; Yousem David M; Hammond Edward; Quigg Megan; Trecker Carrilin; McArthur Justin C; Nath Avindra; Greenberg Benjamin M; Calabresi Peter A; Kerr Douglas A
Reduction of disease activity and disability with high-dose cyclophosphamide in patients with aggressive multiple sclerosis.
Archives of neurology 2008;65(8):1044-51.
2008: Luznik Leo; O'Donnell Paul V; Symons Heather J; Chen Allen R; Leffell M Susan; Zahurak Marianna; Gooley Ted A; Piantadosi Steve; Kaup Michele; Ambinder Richard F; Huff Carol Ann; Matsui William; Bolaños-Meade Javier; Borrello Ivan; Powell Jonathan D; Harrington Elizabeth; Warnock Sandy; Flowers Mary; Brodsky Robert A; Sandmaier Brenda M; Storb Rainer F; Jones Richard J; Fuchs Ephraim J
HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(6):641-50.
2008: Tehlirian C V; Hummers L K; White B; Brodsky R A; Wigley F M
High-dose cyclophosphamide without stem cell rescue in scleroderma.
Annals of the rheumatic diseases 2008;67(6):775-81.
2008: Brodsky Robert A
Narrative review: paroxysmal nocturnal hemoglobinuria: the physiology of complement-related hemolytic anemia.
Annals of internal medicine 2008;148(8):587-95.
2008: Chen Guibin; Ye Zhaohui; Yu Xiaobing; Zou Jizhong; Mali Prashant; Brodsky Robert A; Cheng Linzhao
Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins.
Cell stem cell 2008;2(4):345-55.
2008: Brodsky Robert A
Advances in the diagnosis and therapy of paroxysmal nocturnal hemoglobinuria.
Blood reviews 2008;22(2):65-74.
2008: Brodsky Robert A; Young Neal S; Antonioli Elisabetta; Risitano Antonio M; Schrezenmeier Hubert; Schubert Jörg; Gaya Anna; Coyle Luke; de Castro Carlos; Fu Chieh-Lin; Maciejewski Jaroslaw P; Bessler Monica; Kroon Henk-André; Rother Russell P; Hillmen Peter
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.
Blood 2008;111(4):1840-7.
2008: Brodsky Robert A
Paroxysmal nocturnal hemoglobinuria: stem cells and clonality.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2008;():111-5.
2008: Drachman Daniel B; Adams Robert N; Hu Rong; Jones Richard J; Brodsky Robert A
Rebooting the immune system with high-dose cyclophosphamide for treatment of refractory myasthenia gravis.
Annals of the New York Academy of Sciences 2008;1132():305-14.
2007: Hillmen Peter; Muus Petra; Dührsen Ulrich; Risitano Antonio M; Schubert Jörg; Luzzatto Lucio; Schrezenmeier Hubert; Szer Jeffrey; Brodsky Robert A; Hill Anita; Socié Gerard; Bessler Monica; Rollins Scott A; Bell Leonard; Rother Russell P; Young Neal S
Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.
Blood 2007;110(12):4123-8.
2007: Savage William J; DeRusso Patricia A; Resar Linda M; Chen Allen R; Higman Meghan A; Loeb David M; Jones Richard J; Brodsky Robert A
Treatment of hepatitis-associated aplastic anemia with high-dose cyclophosphamide.
Pediatric blood & cancer 2007;49(7):947-51.
2007: Rother Russell P; Rollins Scott A; Mojcik Christopher F; Brodsky Robert A; Bell Leonard
Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria.
Nature biotechnology 2007;25(11):1256-64.
2007: Bolaños-Meade Javier; Garrett-Mayer Elizabeth; Luznik Leo; Anders Viki; Webb Jennifer; Fuchs Ephraim J; Huff Carol Ann; Matsui William; Borrello Ivan M; Brodsky Robert; Kasamon Yvette L; Swinnen Lode J; Flinn Ian W; Ambinder Richard F; Jones Richard J; Hess Allan D; Vogelsang Georgia B
Induction of autologous graft-versus-host disease: results of a randomized prospective clinical trial in patients with poor risk lymphoma.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(10):1185-91.
2007: Savage William J; Brodsky Robert A
New insights into paroxysmal nocturnal hemoglobinuria.
Hematology (Amsterdam, Netherlands) 2007;12(5):371-6.
2006: Hillmen Peter; Young Neal S; Schubert Jörg; Brodsky Robert A; Socié Gerard; Muus Petra; Röth Alexander; Szer Jeffrey; Elebute Modupe O; Nakamura Ryotaro; Browne Paul; Risitano Antonio M; Hill Anita; Schrezenmeier Hubert; Fu Chieh-Lin; Maciejewski Jaroslaw; Rollins Scott A; Mojcik Christopher F; Rother Russell P; Luzzatto Lucio
The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.
The New England journal of medicine 2006;355(12):1233-43.
2006: Brodsky Robert A; Hu Rong
PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis.
Leukemia & lymphoma 2006;47(7):1215-21.
2006: Maroney S A; Cunningham A C; Ferrel J; Hu R; Haberichter S; Mansbach C M; Brodsky R A; Dietzen D J; Mast A E
A GPI-anchored co-receptor for tissue factor pathway inhibitor controls its intracellular trafficking and cell surface expression.
Journal of thrombosis and haemostasis : JTH 2006;4(5):1114-24.
2006: Huff Carol Ann; Fuchs Ephraim J; Smith B Douglas; Blackford Amanda; Garrett-Mayer Elizabeth; Brodsky Robert A; Flinn Ian W; Ambinder Richard F; Borrello Ivan M; Matsui William H; Vogelsang Georgia B; Griffin Constance A; Luznik Leo; Jones Richard J
Graft-versus-host reactions and the effectiveness of donor lymphocyte infusions.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(4):414-21.
2006: Matsui W H; Brodsky R A; Smith B D; Borowitz M J; Jones R J
Quantitative analysis of bone marrow CD34 cells in aplastic anemia and hypoplastic myelodysplastic syndromes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(3):458-62.
2006: Kuo George P; Brodsky Robert A; Kim Hyun S
Catheter-directed thrombolysis and thrombectomy for the Budd-Chiari syndrome in paroxysmal nocturnal hemoglobinuria in three patients.
Journal of vascular and interventional radiology : JVIR 2006;17(2 Pt 1):383-7.
2006: Petri Michelle; Brodsky Robert
High-dose cyclophosphamide and stem cell transplantation for refractory systemic lupus erythematosus.
JAMA : the journal of the American Medical Association 2006;295(5):559-60.
2006: Brodsky Robert A
New insights into paroxysmal nocturnal hemoglobinuria.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2006;():24-8, 516.
2005: Armanios Mary; Chen Jiunn-Liang; Chang Yen-Pei Christy; Brodsky Robert A; Hawkins Anita; Griffin Constance A; Eshleman James R; Cohen Alan R; Chakravarti Aravinda; Hamosh Ada; Greider Carol W
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15960-4.
2005: Veidt Robin G; Ansari-Lari Ali; Brodsky Robert A
Severe aplastic anemia associated with paroxysmal nocturnal hemoglobinuria and lymphoplasmacytic lymphoma.
Leukemia & lymphoma 2005;46(8):1243-6.
2005: Brodsky Robert A; Jones Richard J
Aplastic anaemia.
Lancet 2005;365(9471):1647-56.
2005: Hu Rong; Mukhina Galina L; Piantadosi Steven; Barber Jamie P; Jones Richard J; Brodsky Robert A
PIG-A mutations in normal hematopoiesis.
Blood 2005;105(10):3848-54.
2005: Drachman Daniel B; Brodsky Robert A
High-dose therapy for autoimmune neurologic diseases.
Current opinion in oncology 2005;17(2):83-8.
2004: Brodsky Robert
Acquired severe aplastic anemia in children: is there a standard of care?
Pediatric blood & cancer 2004;43(7):711-2.
2004: Brodsky R A; Jones R J
Riddle: what do aplastic anemia, acute promyelocytic leukemia, and chronic myeloid leukemia have in common?
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(10):1740-2.
2004: Moyo Victor M; Mukhina Galina L; Garrett Elizabeth S; Brodsky Robert A
Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays.
British journal of haematology 2004;126(1):133-8.
2004: Brodsky Robert A; Chen Allen R; Brodsky Isadore; Jones Richard J
High-dose cyclophosphamide as salvage therapy for severe aplastic anemia.
Experimental hematology 2004;32(5):435-40.
2004: Jones Richard J; Brodsky Robert A
High-dose cyclophosphamide in severe aplastic anaemia.
British journal of haematology 2004;125(3):408-9; author reply 409-10.
2004: Nagajothi Nagaprasad; Matsui William H; Mukhina Galina L; Brodsky Robert A
Enhanced cytotoxicity of rituximab following genetic and biochemical disruption of glycosylphosphatidylinositol anchored proteins.
Leukemia & lymphoma 2004;45(4):795-9.
2003: Nousari Carlos H; Brodsky Robert; Anhalt Grant J
Evaluating the role of immunoablative high-dose cyclophosphamide therapy in pemphigus vulgaris.
Journal of the American Academy of Dermatology 2003;49(1):148-50.
2003: Huff Carol Ann; Fuchs Ephraim J; Noga Stephen J; O'Donnell Paul V; Ambinder Richard F; Diehl Louis; Borrello Ivan; Vogelsang Georgia B; Miller Carole B; Flinn Ian A; Brodsky Robert A; Marcellus Deborah; Jones Richard J
Long-term follow-up of T cell-depleted allogeneic bone marrow transplantation in refractory multiple myeloma: importance of allogeneic T cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2003;9(5):312-9.
2003: Wainwright Linda; Brodsky Robert A; Erasmus Linda K; Poyiadjis Stelios; Naidu Gita; MacKinnon Diane
Paroxysmal nocturnal hemoglobinuria arising from Fanconi anemia.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2003;25(2):167-8.
2003: Petri Michelle; Jones Richard J; Brodsky Robert A
High-dose cyclophosphamide without stem cell transplantation in systemic lupus erythematosus.
Arthritis and rheumatism 2003;48(1):166-73.
2003: Drachman Daniel B; Jones Richard J; Brodsky Robert A
Treatment of refractory myasthenia: "rebooting" with high-dose cyclophosphamide.
Annals of neurology 2003;53(1):29-34.
2002: Hsu Jack W; Czander Magalena; Anders Viki; Vogelsang Georgia; Brodsky Robert A
Parvovirus b19-associated pure red cell aplasia in chronic graft-versus-host disease.
British journal of haematology 2002;119(1):280-1.
2002: Hsu J W; Vogelsang G; Jones R J; Brodsky R A
Bone marrow transplantation in Shwachman-Diamond syndrome.
Bone marrow transplantation 2002;30(4):255-8.
2002: Moyo Victor M; Smith Douglas; Brodsky Isadore; Crilley Pamela; Jones Richard J; Brodsky Robert A
High-dose cyclophosphamide for refractory autoimmune hemolytic anemia.
Blood 2002;100(2):704-6.
2002: Brodsky Robert A
High dose cyclophosphamide treatment for autoimmune disorders.
TheScientificWorldJournal 2002;2():1808-15.
2002: Matsui William H; Gladstone Douglas E; Vala Milada S; Barber James P; Brodsky Robert A; Smith B Douglas; Jones Richard J
The role of growth factors in the activity of pharmacological differentiation agents.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2002;13(6):275-83.
2002: Smith B Douglas; Jones Richard J; Lee Shing M; Piantadosi Steve; Vala Milada S; Fuller Don; Gore Steven D; Noga Steven J; O'Donnell Paul V; Braine Hayden; Vogelsang Georgia B; Fuchs Ephraim J; Flinn Ian W; Brodsky Robert A; Ambinder Richard F; Miller Carole B
Autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide purging for acute myeloid leukaemia beyond first remission: a 10-year experience.
British journal of haematology 2002;117(4):907-13.
2002: Brodsky Robert A
High-dose cyclophosphamide for aplastic anemia and autoimmunity.
Current opinion in oncology 2002;14(2):143-6.
2002: Mukhina Galina L; Buckley Thomas; Brodsky Robert A
A rapid spectrophotometric screening assay for paroxysmal nocturnal hemoglobinuria.
Acta haematologica 2002;107(3):182-4.
2001: Akpek G; Ambinder R F; Piantadosi S; Abrams R A; Brodsky R A; Vogelsang G B; Zahurak M L; Fuller D; Miller C B; Noga S J; Fuchs E; Flinn I W; O'Donnell P; Seifter E J; Mann R B; Jones R J
Long-term results of blood and marrow transplantation for Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(23):4314-21.
2001: Mukhina G L; Buckley J T; Barber J P; Jones R J; Brodsky R A
Multilineage glycosylphosphatidylinositol anchor-deficient haematopoiesis in untreated aplastic anaemia.
British journal of haematology 2001;115(2):476-82.
2001: Brodsky R A; Sensenbrenner L L; Smith B D; Dorr D; Seaman P J; Lee S M; Karp J E; Brodsky I; Jones R J
Durable treatment-free remission after high-dose cyclophosphamide therapy for previously untreated severe aplastic anemia.
Annals of internal medicine 2001;135(7):477-83.
2001: Brodsky R A; Jones R J
High-dose cyclophosphamide in aplastic anaemia.
Lancet 2001;357(9262):1128-9.
2001: Brodsky R A; Fuller A K; Ratner L E; Leffell M S; Jones R J
Elimination of alloantibodies by immunoablative high-dose cyclophosphamide.
Transplantation 2001;71(3):482-4.
2001: Chen R; Eshleman J R; Brodsky R A; Medof M E
Glycophosphatidylinositol-anchored protein deficiency as a marker of mutator phenotypes in cancer.
Cancer research 2001;61(2):654-8.
2000: Brodsky R A; Mukhina G L; Li S; Nelson K L; Chiurazzi P L; Buckley J T; Borowitz M J
Improved detection and characterization of paroxysmal nocturnal hemoglobinuria using fluorescent aerolysin.
American journal of clinical pathology 2000;114(3):459-66.
2000: Brodsky R A; Petri M; Jones R J
Hematopoietic stem cell transplantation for systemic lupus erythematosus.
Rheumatic diseases clinics of North America 2000;26(2):377-87, viii.
1999: Nelson K L; Brodsky R A; Buckley J T
Channels formed by subnanomolar concentrations of the toxin aerolysin trigger apoptosis of T lymphomas.
Cellular microbiology 1999;1(1):69-74.
1999: Nousari H C; Brodsky R A; Jones R J; Grever M R; Anhalt G J
Immunoablative high-dose cyclophosphamide without stem cell rescue in paraneoplastic pemphigus: report of a case and review of this new therapy for severe autoimmune disease.
Journal of the American Academy of Dermatology 1999;40(5 Pt 1):750-4.
1999: Brodsky R A; Smith B D
Bone marrow transplantation for autoimmune diseases.
Current opinion in oncology 1999;11(2):83-6.
1999: Brodsky R A; Mukhina G L; Nelson K L; Lawrence T S; Jones R J; Buckley J T
Resistance of paroxysmal nocturnal hemoglobinuria cells to the glycosylphosphatidylinositol-binding toxin aerolysin.
Blood 1999;93(5):1749-56.
1999: Gladstone D E; Bedi A; Miller C B; Noga S J; Griffin C A; Piantadosi S; Cagnoni P J; Brodsky R A; Smith B D; Douglas T T; Shpall E J; Jones R J
Philadelphia chromosome-negative engraftment after autologous transplantation with granulocyte-macrophage colony-stimulating factor for chronic myeloid leukemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1999;5(6):394-9.
1998: Brodsky R A; Petri M; Smith B D; Seifter E J; Spivak J L; Styler M; Dang C V; Brodsky I; Jones R J
Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease.
Annals of internal medicine 1998;129(12):1031-5.
1998: Smith B D; Bambach B J; Vala M S; Barber J P; Enger C; Brodsky R A; Burke P J; Gore S D; Jones R J
Inhibited apoptosis and drug resistance in acute myeloid leukaemia.
British journal of haematology 1998;102(4):1042-9.
1998: Brodsky R A
Biology and management of acquired severe aplastic anemia.
Current opinion in oncology 1998;10(2):95-9.
1997: Brodsky R A; Vala M S; Barber J P; Medof M E; Jones R J
Resistance to apoptosis caused by PIG-A gene mutations in paroxysmal nocturnal hemoglobinuria.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8756-60.
1996: Brodsky R A; Bedi A; Jones R J
Are growth factors leukemogenic?
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(1):175-7.
1996: Brodsky R A; Sensenbrenner L L; Jones R J
Complete remission in severe aplastic anemia after high-dose cyclophosphamide without bone marrow transplantation.
Blood 1996;87(2):491-4.
1995: Nagarajan S; Brodsky R A; Young N S; Medof M E
Genetic defects underlying paroxysmal nocturnal hemoglobinuria that arises out of aplastic anemia.
Blood 1995;86(12):4656-61.
1995: Prince G M; Nguyen M; Lazarus H M; Brodsky R A; Terstappen L W; Medof M E
Peripheral blood harvest of unaffected CD34+ CD38- hematopoietic precursors in paroxysmal nocturnal hemoglobinuria.
Blood 1995;86(9):3381-6.
1994: Brodsky R A; Jane S M; Vanin E F; Mitsuya H; Peters T R; Shimada T; Medof M E; Nienhuis A W
Purified GPI-anchored CD4DAF as a receptor for HIV-mediated gene transfer.
Human gene therapy 1994;5(10):1231-9.
1994: Brodsky R A; Hasegawa S; Fibach E; Dunbar C E; Young N S; Rodgers G P
Acquired sideroblastic anaemia following progesterone therapy.
British journal of haematology 1994;87(4):859-62.
1990: Brodsky R; Topolsky D; Crilley P; Bulova S; Brodsky I
Frequency of veno-occlusive disease of the liver in bone marrow transplantation with a modified busulfan/cyclophosphamide preparative regimen.
American journal of clinical oncology 1990;13(3):221-5.

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