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Fiona Yull

Research Profile

Chemicals & Drugs

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Physiology

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Publications

TOP 3
Wei Han; Hui Li; Vasiliy V Polosukhin; Brahm H Segal; Fiona E Yull; Jiyang Cai; Linda A Gleaves; Timothy S Blackwell
NADPH Oxidase Limits Lipopolysaccharide-Induced Lung Inflammation and Injury in Mice through Reduction-Oxidation Regulation of NF-κB Activity.
James R Edwards; Linda Connelly; Nicole Fleming; Seint T Lwin; Megan M Moore; Gregory R Mundy; Jeffry S Nyman; Koichiro Ono; Daniel S Perrien; Fiona E Yull; Florent Elefteriou
Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.
Shann S Yu; Fiona E Yull; Whitney J Barham; Craig L Duvall; Cheryl M Lau; Hongmei Li; Christopher E Nelson; Halina M Onishko; Chelsey A Smith; Todd D Giorgio
Macrophage-specific RNA interference targeting via "click", mannosylated polymeric micelles.

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All Publications

2013: Wei Han; Hui Li; Vasiliy V Polosukhin; Brahm H Segal; Fiona E Yull; Jiyang Cai; Linda A Gleaves; Timothy S Blackwell
NADPH Oxidase Limits Lipopolysaccharide-Induced Lung Inflammation and Injury in Mice through Reduction-Oxidation Regulation of NF-κB Activity.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(9):4786-94.
2013: James R Edwards; Linda Connelly; Nicole Fleming; Seint T Lwin; Megan M Moore; Gregory R Mundy; Jeffry S Nyman; Koichiro Ono; Daniel S Perrien; Fiona E Yull; Florent Elefteriou
Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013;28(4):960-9.
2013: Shann S Yu; Fiona E Yull; Whitney J Barham; Craig L Duvall; Cheryl M Lau; Hongmei Li; Christopher E Nelson; Halina M Onishko; Chelsey A Smith; Todd D Giorgio
Macrophage-specific RNA interference targeting via "click", mannosylated polymeric micelles.
Molecular pharmaceutics 2013;10(3):975-87.
2012: R Zaynagetdinov; W Zhou; J A Ausborn; Dong-sheng Cheng; L Connelly; Barbara Fingleton; A G McLoed; R Stokes Peebles; Vasiliy V Polosukhin; L S Prince; Taylor P Sherrill; georgios stathopoulos; Fiona E Yull; Timothy S Blackwell
Epithelial nuclear factor-κB signaling promotes lung carcinogenesis via recruitment of regulatory T lymphocytes.
Oncogene 2012;31(26):3164-76.
2012: Melody Swartz; Melissa H Wong; Fiona E Yull; Lisa M Coussens; Noriho Iida; Edward W Roberts; Sabina Sangaletti; Yves A DeClerck
Tumor microenvironment complexity: emerging roles in cancer therapy.
Cancer research 2012;72(10):2473-80.
2012: Karabela Sophia; Frank McMahon; Ioannis Psallidas; Charis Roussos; Taylor P Sherrill; Timothy S Blackwell; Dong-sheng Cheng; Linda A Gleaves; Wei Han; Chrysoula A Kairi; Ioannis Kalomenidis; Ioannis Stathopoulos; Spyridoula Vassiliou; Fiona E Yull; Spyros G Zakynthinos; Rinat Zaynagetdinov; Georgios T Stathopoulos
Opposing effects of bortezomib-induced nuclear factor-κB inhibition on chemical lung carcinogenesis.
Carcinogenesis 2012;33(4):859-67.
2012: Yasunobu Arima; Ulrich A K Betz; Timothy S Blackwell; Masaya Harada; Toshio Hirano; Yoichiro Iwakura; Daisuke Kamimura; Tadafumi Kawamoto; Fuminori Kawano; Gabriel Márquez; Yoshinobu Ohira; Jin-Haeng Park; Fiona E Yull; Masaaki Murakami
Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier.
Cell 2012;148(3):447-57.
2012: Whitney Barham; Timothy S Blackwell; Linda Connelly; Taylor Sherrill; Fiona E Yull
Intraductal injection of LPS as a mouse model of mastitis: signaling visualized via an NF-κB reporter transgenic.
Journal of visualized experiments : JoVE 2012;(67):e4030.
2011: Rinat Zaynagetdinov; Jamie A Ausborn; Amber L Degryse; Linda A Gleaves; Wei Han; Allyson G McLoed; Frank B McMahon; Vasiliy V Polosukhin; Taylor P Sherrill; Georgios T Stathopoulos; Fiona E Yull; Timothy S Blackwell
A critical role for macrophages in promotion of urethane-induced lung carcinogenesis.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(11):5703-11.
2011: Timothy S Blackwell; Wei Han; Ashley N Hipps; Michael C Ostrowski; Yasutoshi Yamamoto; Fiona E Yull; Whitney J Barham; Lawrence S Prince
NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(5):2740-7.
2011: William E Lawson; Edward E Morrisey; Dawn C Newcomb; Vasiliy V Polosukhin; Juan Roldan; Harikrishna Tanjore; Xiaochuan C Xu; Fiona E Yull; Dong-sheng Cheng; Amber L Degryse; Brittany R Jones; Kirk B Lane; Michael F Beers; Timothy S Blackwell
Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(26):10562-7.
2011: L Connelly; W Barham; H M Onishko; T Sherrill; L A Chodosh; T S Blackwell; Fiona E Yull
Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden.
Oncogene 2011;30(12):1402-12.
2011: Sangwoon Chung; Jae-Woong Hwang; Vuokko L Kinnula; Timothy S Blackwell; Michael Bulger; Isaac Kirubakaran Sundar; Hongwei Yao; Fiona E Yull; Irfan Rahman
NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.
PloS one 2011;6(8):e23488.
2011: Linda Connelly; Halina M Onishko; Michael C Ostrowski; Taylor P Sherrill; Whitney Barham; Timothy S Blackwell; Lianyi Chen; Tahera Zabuawala; Fiona E Yull
NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model.
Breast cancer research : BCR 2011;13(4):R83.
2011: Aaron C-H Chen; Praveen R Arany; Timothy S Blackwell; Ying-Ying Huang; Gitika B Kharkwal; David Mooney; Taimur Saleem; Sulbha K Sharma; Elizabeth M Tomkinson; Fiona E Yull; Michael R Hamblin
Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts.
PloS one 2011;6(7):e22453.
2010: georgios stathopoulos; Taylor P Sherrill; Karabela Sophia; Kasia Goleniewska; Ioannis Kalomenidis; Charis Roussos; Barbara Fingleton; Fiona E Yull; R Stokes Peebles; Timothy S Blackwell
Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion.
American journal of respiratory and critical care medicine 2010;182(10):1273-81.
2010: Jinming Yang; Ryan Splittgerber; Fiona E Yull; Sara Kantrow; Gregory D Ayers; Michael Karin; Ann Richmond
Conditional ablation of Ikkb inhibits melanoma tumor development in mice.
The Journal of clinical investigation 2010;120(7):2563-74.
2010: Brahm H Segal; Wei Han; Jennifer J Bushey; Myungsoo Joo; Zahida Bhatti; Joy Feminella; Carly G Dennis; R Robert Vethanayagam; Fiona E Yull; Maegan Capitano; Paul K Wallace; Hans Minderman; John W Christman; Michael B Sporn; Jefferson Chan; Donald Vinh; Steven M Holland; Luigina R Romani; Sarah L Gaffen; Michael L Freeman; Timothy S Blackwell
NADPH oxidase limits innate immune responses in the lungs in mice.
PloS one 2010;5(3):e9631.
2010: Linda Connelly; Whitney Barham; Rachel Pigg; Leshana Saint-Jean; Taylor Sherrill; Dong-Sheng Cheng; Lewis A Chodosh; Timothy S Blackwell; Fiona E Yull
Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection.
Journal of cellular physiology 2010;222(1):73-81.
2009: Shian-Huey Chiang; Merlijn Bazuine; Carey N Lumeng; Lynn M Geletka; Jonathan Mowers; Nicole Marie White; Jing-Tyan Ma; Jie Zhou; Nathan R Qi; Dan Westcott; Jennifer B Delproposto; Timothy S Blackwell; Fiona E Yull; Alan Saltiel
The protein kinase IKKepsilon regulates energy balance in obese mice.
Cell 2009;138(5):961-75.
2009: Madhu Singh; Ann Kapoun; Linda Higgins; William Kutschke; Joshua M Thurman; Rong Zhang; Minati Singh; Jinying Yang; Xiaoqun Guan; John S Lowe; Robert M Weiss; Kathy Zimmermann; Fiona E Yull; Timothy S Blackwell; Peter J Mohler; Mark E Anderson
Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart.
The Journal of clinical investigation 2009;119(4):986-96.
2009: Wei Han; Myungsoo Joo; M Brett Everhart; John W Christman; Fiona E Yull; Timothy S Blackwell
Myeloid cells control termination of lung inflammation through the NF-kappaB pathway.
American journal of physiology. Lung cellular and molecular physiology 2009;296(3):L320-7.
2008: S M Chen; Dong-sheng Cheng; B J Williams; Taylor P Sherrill; Wei Han; M Chont; L Saint-Jean; John W Christman; Ruxana T Sadikot; Fiona E Yull; Timothy S Blackwell
The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.
Clinical and experimental immunology 2008;153(3):420-8.
2008: georgios stathopoulos; Taylor P Sherrill; Wei Han; Ruxana T Sadikot; Fiona E Yull; Timothy S Blackwell; Barbara Fingleton
Host nuclear factor-kappaB activation potentiates lung cancer metastasis.
Molecular cancer research : MCR 2008;6(3):364-71.
2008: georgios stathopoulos; Taylor P Sherrill; Wei Han; Ruxana T Sadikot; Vasiliy V Polosukhin; Barbara Fingleton; Fiona E Yull; Timothy S Blackwell
Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis.
Clinical & experimental metastasis 2008;25(1):43-51.
2007: georgios stathopoulos; Taylor P Sherrill; Dong-sheng Cheng; Robert M Scoggins; Wei Han; Vasiliy V Polosukhin; Linda Connelly; Fiona E Yull; Barbara Fingleton; Timothy S Blackwell
Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18514-9.
2007: Gye Young Parkgy; N Hu; X Wang; Ruxana T Sadikot; Fiona E Yull; Myungsoo Joo; R S Peebles; Timothy S Blackwell; John W Christman
Conditional regulation of cyclooxygenase-2 in tracheobronchial epithelial cells modulates pulmonary immunity.
Clinical and experimental immunology 2007;150(2):245-54.
2007: Dong-sheng Cheng; Wei Han; Sabrina M Chen; Taylor P Sherrill; Melissa Chont; Gye Young Parkgy; James R Sheller; Vasiliy V Polosukhin; John W Christman; Fiona E Yull; Timothy S Blackwell
Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6504-13.
2007: Linda Connelly; Cheryl L Robinson-Benion; Melissa Chont; Leshana Saint-Jean; Haijing Li; Vasiliy V Polosukhin; Timothy S Blackwell; Fiona E Yull
A transgenic model reveals important roles for the NF-kappa B alternative pathway (p100/p52) in mammary development and links to tumorigenesis.
The Journal of biological chemistry 2007;282(13):10028-35.
2006: M Brett Everhart; Wei Han; Taylor P Sherrill; Melissa Arutiunov; Vasiliy V Polosukhin; James R Burke; Ruxana T Sadikot; John W Christman; Fiona E Yull; Timothy S Blackwell
Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4995-5005.
2006: Ruxana T Sadikot; Heng Zeng; Myungsoo Joo; M Brett Everhart; Taylor P Sherrill; Bo Li; Dong-sheng Cheng; Fiona E Yull; John W Christman; Timothy S Blackwell
Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4923-30.
2006: Diana M Stafforini; James R Sheller; Timothy S Blackwell; Adam Sapirstein; Fiona E Yull; Thomas M McIntyre; Joseph V Bonventre; Stephen M Prescott; L Jackson Roberts
Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases.
The Journal of biological chemistry 2006;281(8):4616-23.
2006: georgios stathopoulos; Zhiwen Zhu; M Brett Everhart; Ioannis Kalomenidis; William E Lawson; Semra Bilaceroglu; Todd E Peterson; Daphne Mitchell; Fiona E Yull; Richard W Light; Timothy S Blackwell
Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
American journal of respiratory cell and molecular biology 2006;34(2):142-50.
2005: Sean M O'Donnell; Mark W Hansberger; Jodi L Connolly; James D Chappell; Melissa J Watson; Janene M Pierce; J Denise Wetzel; Wei Han; Erik S Barton; J Craig Forrest; Tibor Valyi-Nagy; Fiona E Yull; Timothy S Blackwell; Jeffrey N Rottman; Barbara Sherry; Terence S Dermody
Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease.
The Journal of clinical investigation 2005;115(9):2341-50.
2005: M Brett Everhart; Wei Han; Kelly S Parman; Vasiliy V Polosukhin; Heng Zeng; Ruxana T Sadikot; Bo Li; Fiona E Yull; John W Christman; Timothy S Blackwell
Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation.
Journal of leukocyte biology 2005;77(2):173-80.
2004: Usha Ponnappan; Fiona E Yull; Lee S F Soderberg
Inhaled isobutyl nitrite inhibited macrophage inducible nitric oxide by blocking NFkappaB signaling and promoting degradation of inducible nitric oxide synthase-2.
International immunopharmacology 2004;4(8):1075-82.
2004: Claus Schneider; W David Strayhorn; Dana M Brantley; Lillian B Nanney; Fiona E Yull; Alan R Brash
Upregulation of 8-lipoxygenase in the dermatitis of IkappaB-alpha-deficient mice.
The Journal of investigative dermatology 2004;122(3):691-8.
2004: Ruxana T Sadikot; Heng Zeng; Fiona E Yull; Bo Li; Dong-sheng Cheng; Douglas S Kernodle; E Duco Jansen; Christopher H Contag; Brahm H Segal; Steven M Holland; Timothy S Blackwell; John W Christman
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1801-8.
2003: Fiona E Yull; Wei Han; E Duco Jansen; M Brett Everhart; Ruxana T Sadikot; John W Christman; Timothy S Blackwell
Bioluminescent detection of endotoxin effects on HIV-1 LTR-driven transcription in vivo.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(6):741-9.
2003: Keith D Gray; Misho O Simovic; William C Chapman; Timothy S Blackwell; John W Christman; M Kay Washington; Fiona E Yull; Nada Jaffal; E Duco Jansen; Shiva Gautman; Steven C Stain
Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis.
The Journal of surgical research 2003;110(1):310-4.
2003: Ruxana T Sadikot; Wei Han; M Brett Everhart; Ornella Zoia; R Stokes Peebles; E Duco Jansen; Fiona E Yull; John W Christman; Timothy S Blackwell
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):1091-8.
2002: Ruxana T Sadikot; L James Wudel; Duco E Jansen; Jacob P Debelak; Fiona E Yull; John W Christman; Timothy S Blackwell; William C Chapman
Hepatic cryoablation-induced multisystem injury: bioluminescent detection of NF-kappaB activation in a transgenic mouse model.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2002;6(2):264-70.
2001: Ruxana T Sadikot; E Duco Jansen; Thomas R Blackwell; Ornella Zoia; Fiona E Yull; John W Christman; Timothy S Blackwell
High-dose dexamethasone accentuates nuclear factor-kappa b activation in endotoxin-treated mice.
American journal of respiratory and critical care medicine 2001;164(5):873-8.
2001: PB Bushdid; CL Chen; Dana M Brantley; Fiona E Yull; R Raghow; LD Kerr; Joey V Barnett
NF-kappaB mediates FGF signal regulation of msx-1 expression.
Developmental biology 2001;237(1):107-15.
2001: Dana M Brantley; CL Chen; Rebecca Cook; PB Bushdid; J L Bradberry; F Kittrell; D Medina; Lynn M Matrisian; LD Kerr; Fiona E Yull
Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epithelium.
Molecular biology of the cell 2001;12(5):1445-55.
2000: CL Chen; Fiona E Yull; Nancy L Cardwell; N Singh; W David Strayhorn; Lillian B Nanney; LD Kerr
RAG2-/-, I kappa B-alpha-/- chimeras display a psoriasiform skin disease.
The Journal of investigative dermatology 2000;115(6):1124-33.
2000: C L Chen; N Singh; Fiona E Yull; D Strayhorn; L Van Kaer; L D Kerr
Lymphocytes lacking I kappa B-alpha develop normally, but have selective defects in proliferation and function.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5418-27.
2000: Chuan-Ming Hao; Fiona E Yull; T Blackwell; Martin Kömhoff; Linda S Davis; Matthew D Breyer
Dehydration activates an NF-kappaB-driven, COX2-dependent survival mechanism in renal medullary interstitial cells.
The Journal of clinical investigation 2000;106(8):973-82.
2000: Dana M Brantley; Fiona E Yull; Rebecca Cook; Donna J Hicks; C M Cook; LD Kerr
Dynamic expression and activity of NF-kappaB during post-natal mammary gland morphogenesis.
Mechanisms of development 2000;97(1-2):149-55.
2000: Rebecca Cook; PB Bushdid; Dana M Brantley; Fiona E Yull; LD Kerr
Mesenchymal expression of nuclear factor-kappaB inhibits epithelial growth and branching in the embryonic chick lung.
Developmental biology 2000;225(2):322-38.
2000: Timothy S Blackwell; Fiona E Yull; CL Chen; A Venkatakrishnan; Thomas R Blackwell; Donna J Hicks; LH Lancaster; John W Christman; LD Kerr
Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation.
American journal of respiratory and critical care medicine 2000;162(3 Pt 1):1095-101.
2000: U S Sohur; CL Chen; Donna J Hicks; Fiona E Yull; LD Kerr
Nuclear factor-kappaB/Rel is apoptogenic in cytokine withdrawal-induced programmed cell death.
Cancer research 2000;60(5):1202-5.
1999: Timothy S Blackwell; Fiona E Yull; CL Chen; A Venkatakrishnan; Thomas R Blackwell; Donna J Hicks; LH Lancaster; John W Christman; LD Kerr
Use of genetically altered mice to investigate the role of nuclear factor-kappa B activation and cytokine gene expression in sepsis-induced ARDS.
Chest 1999;116(1 Suppl):73S-74S.
1999: CL Chen; Fiona E Yull; LD Kerr
Differential serine phosphorylation regulates IkappaB-alpha inactivation.
Biochemical and biophysical research communications 1999;257(3):798-806.
1998: PB Bushdid; Dana M Brantley; Fiona E Yull; Gareth L Blaeuer; LH Hoffman; L Niswander; LD Kerr
Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.
Nature 1998;392(6676):615-8.