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Alfred Yung

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Friedman Henry S; Prados Michael D; Wen Patrick Y; Mikkelsen Tom; Schiff David; Abrey Lauren E; Yung W K Alfred; Paleologos Nina; Nicholas Martin K; Jensen Randy; Vredenburgh James; Huang Jane; Zheng Maoxia; Cloughesy Timothy
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.
Groves Morris D; Hess Kenneth R; Puduvalli Vinay K; Colman Howard; Conrad Charles A; Gilbert Mark R; Weinberg Jeffrey; Cristofanilli Massimo; Yung W K Alfred; Liu Ta-Jen
Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma.
Liu Ta-Jen; Koul Dimpy; LaFortune Tiffany; Tiao Ningyi; Shen Rui Jun; Maira Sauveur-Michel; Garcia-Echevrria Carlos; Yung W K Alfred
NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas.

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All Publications

2009: Friedman Henry S; Prados Michael D; Wen Patrick Y; Mikkelsen Tom; Schiff David; Abrey Lauren E; Yung W K Alfred; Paleologos Nina; Nicholas Martin K; Jensen Randy; Vredenburgh James; Huang Jane; Zheng Maoxia; Cloughesy Timothy
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(28):4733-40.
2009: Groves Morris D; Hess Kenneth R; Puduvalli Vinay K; Colman Howard; Conrad Charles A; Gilbert Mark R; Weinberg Jeffrey; Cristofanilli Massimo; Yung W K Alfred; Liu Ta-Jen
Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma.
Journal of neuro-oncology 2009;94(2):229-34.
2009: Liu Ta-Jen; Koul Dimpy; LaFortune Tiffany; Tiao Ningyi; Shen Rui Jun; Maira Sauveur-Michel; Garcia-Echevrria Carlos; Yung W K Alfred
NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas.
Molecular cancer therapeutics 2009;8(8):2204-10.
2009: Yung W K Alfred
Quality of life: a fertile field for inquiry.
Neuro-oncology 2009;11(3):241.
2009: Powis Garth; Ihle Nathan T; Yung W K Alfred
Inhibiting PI-3-K for glioma therapy.
Cell cycle (Georgetown, Tex.) 2009;8(3):335.
2008: Weller Michael; Yung W K Alfred
Bevacizumab--news from the fast lane?
Neuro-oncology 2008;10(5):647.
2008: de Groot J F; Gilbert M R; Aldape K; Hess K R; Hanna T A; Ictech S; Groves M D; Conrad C; Colman H; Puduvalli V K; Levin V; Yung W K A
Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma.
Journal of neuro-oncology 2008;90(1):89-97.
2008: de Groot John F; Yung Wai Kwan Alfred
Bevacizumab and irinotecan in the treatment of recurrent malignant gliomas.
Cancer journal (Sudbury, Mass.) 2008;14(5):279-85.
2008: Chang Susan M; Lamborn Kathleen R; Kuhn John G; Yung W K Alfred; Gilbert Mark R; Wen Patrick Y; Fine Howard A; Mehta Minesh P; DeAngelis Lisa M; Lieberman Frank S; Cloughesy Timothy F; Robins H Ian; Abrey Lauren E; Prados Michael D;
Neurooncology clinical trial design for targeted therapies: lessons learned from the North American Brain Tumor Consortium.
Neuro-oncology 2008;10(4):631-42.
2008: de Groot John F; Piao Yuji; Lu Li; Fuller Gregory N; Yung W K Alfred
Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation.
Journal of neuro-oncology 2008;88(2):121-33.
2008: Corn Benjamin W; Moughan Jennifer; Knisely Jonathan P S; Fox Sherry W; Chakravarti Arnab; Yung W K Alfred; Curran Walter J; Robins H Ian; Brachman David G; Henderson Randal H; Mehta Minesh P; Movsas Benjamin
Prospective evaluation of quality of life and neurocognitive effects in patients with multiple brain metastases receiving whole-brain radiotherapy with or without thalidomide on Radiation Therapy Oncology Group (RTOG) trial 0118.
International journal of radiation oncology, biology, physics 2008;71(1):71-8.
2008: Lamborn Kathleen R; Yung W K Alfred; Chang Susan M; Wen Patrick Y; Cloughesy Timothy F; DeAngelis Lisa M; Robins H Ian; Lieberman Frank S; Fine Howard A; Fink Karen L; Junck Larry; Abrey Lauren; Gilbert Mark R; Mehta Minesh; Kuhn John G; Aldape Kenneth D; Hibberts Janelle; Peterson Pamela M; Prados Michael D;
Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas.
Neuro-oncology 2008;10(2):162-70.
2008: Groves Morris D; Glantz Michael J; Chamberlain Marc C; Baumgartner Karen E; Conrad Charles A; Hsu Sigmund; Wefel Jeffrey S; Gilbert Mark R; Ictech Sandra; Hunter Kathy U; Forman Arthur D; Puduvalli Vinay K; Colman Howard; Hess Kenneth R; Yung W K Alfred
A multicenter phase II trial of intrathecal topotecan in patients with meningeal malignancies.
Neuro-oncology 2008;10(2):208-15.
2008: Puduvalli Vinay K; Giglio Pierre; Groves Morris D; Hess Kenneth R; Gilbert Mark R; Mahankali Srikanth; Jackson Edward F; Levin Victor A; Conrad Charles A; Hsu Sigmund H; Colman Howard; de Groot John F; Ritterhouse Melesa G; Ictech Sandra E; Yung W K Alfred
Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme.
Neuro-oncology 2008;10(2):216-22.
2008: Yung W K Alfred
Carrying Neuro-Oncology to a world that needs knowledge.
Neuro-oncology 2008;10(1):1.
2008: Freire Pablo; Vilela Marco; Deus Helena; Kim Yong-Wan; Koul Dimpy; Colman Howard; Aldape Kenneth D; Bogler Oliver; Yung W K Alfred; Coombes Kevin; Mills Gordon B; Vasconcelos Ana T; Almeida Jonas S
Exploratory analysis of the copy number alterations in glioblastoma multiforme.
PloS one 2008;3(12):e4076.
2007: Alonso Marta M; Gomez-Manzano Candelaria; Bekele B Nebiyou; Yung W K Alfred; Fueyo Juan
Adenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter.
Cancer research 2007;67(24):11499-504.
2007: Loghin Monica E; Prados Michael D; Wen Patrick; Junck Larry; Lieberman Frank; Fine Howard; Fink Karen L; Metha Minesh; Kuhn John; Lamborn Kathleen; Chang Susan M; Cloughesy Timothy; DeAngelis Lisa M; Robins Ian H; Aldape Kenneth D; Yung W K Alfred
Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7133-8.
2007: Scheurer Michael E; Etzel Carol J; Liu Mei; El-Zein Randa; Airewele Gladstone E; Malmer Beatrice; Aldape Kenneth D; Weinberg Jeffrey S; Yung W K Alfred; Bondy Melissa L
Aggregation of cancer in first-degree relatives of patients with glioma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(11):2491-5.
2007: Liu Juinn-Lin; Mao Zhenyu; LaFortune Tiffany A; Alonso Marta M; Gallick Gary E; Fueyo Juan; Yung W K Alfred
Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade.
Cancer research 2007;67(22):11054-63.
2007: Jiang Rongcai; Choi Woonyoung; Khan Asad; Hess Kenneth; Gerner Eugene W; Casero Robert A; Yung W K Alfred; Hamilton Stanley R; Zhang Wei
Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma.
International journal of oncology 2007;31(2):431-40.
2007: Alonso M M; Gomez-Manzano C; Jiang H; Bekele N B; Piao Y; Yung W K A; Alemany R; Fueyo J
Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo.
Cancer gene therapy 2007;14(8):756-61.
2007: Pelloski Christopher E; Ballman Karla V; Furth Alfred F; Zhang Li; Lin E; Sulman Erik P; Bhat Krishna; McDonald J Matthew; Yung W K Alfred; Colman Howard; Woo Shiao Y; Heimberger Amy B; Suki Dima; Prados Michael D; Chang Susan M; Barker Fred G; Buckner Jan C; James C David; Aldape Kenneth
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(16):2288-94.
2007: Koul Dimpy; Shen Ruijun; Shishodia Shishir; Takada Yasanuri; Bhat Krishna P; Reddy Shrikanth A G; Aggarwal Bharat B; Yung W K Alfred
PTEN down regulates AP-1 and targets c-fos in human glioma cells via PI3-kinase/Akt pathway.
Molecular and cellular biochemistry 2007;300(1-2):77-87.
2007: Olson Melissa V; Johnson David G; Jiang Hong; Xu Jing; Alonso Marta M; Aldape Kenneth D; Fuller Gregory N; Bekele B Nebiyou; Yung W K Alfred; Gomez-Manzano Candelaria; Fueyo Juan
Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.
Cancer research 2007;67(9):4005-9.
2007: Liu Ta-Jen; LaFortune Tiffany; Honda Toshiyuki; Ohmori Osamu; Hatakeyama Shinji; Meyer Thomas; Jackson Dowdy; de Groot John; Yung W K Alfred
Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo.
Molecular cancer therapeutics 2007;6(4):1357-67.
2007: Xia Dianren; Srinivas Harish; Ahn Young-Ho; Sethi Gautam; Sheng Xiaoyang; Yung W K Alfred; Xia Qianghua; Chiao Paul J; Kim Heetae; Brown Powel H; Wistuba Ignacio I; Aggarwal Bharat B; Kurie Jonathan M
Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway.
The Journal of biological chemistry 2007;282(6):3507-19.
2007: Groves Morris D; Puduvalli Vinay K; Chang Susan M; Conrad Charles A; Gilbert Mark R; Tremont-Lukats Ivo W; Liu Ta-Jen; Peterson Pamela; Schiff David; Cloughesy Timothy F; Wen Patrick Y; Greenberg Harry; Abrey Lauren E; DeAngelis Lisa M; Hess Kenneth R; Lamborn Kathleen R; Prados Michael D; Yung W K Alfred
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
Journal of neuro-oncology 2007;81(3):271-7.
2007: Xia Yan; Wang Ji; Liu Ta-Jen; Yung W K Alfred; Hunter Tony; Lu Zhimin
c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis.
Molecular cell 2007;25(2):219-32.
2007: Yung W K Alfred; James C David
Mapping the future of Neuro-Oncology.
Neuro-oncology 2007;9(1):1-2.
2006: Jiang Hong; Olson Melissa V; Medrano Diana R; Lee Ok-Hee; Xu Jing; Piao Yuji; Alonso Marta M; Gomez-Manzano Candelaria; Hung Mien-Chie; Yung W K Alfred; Fueyo Juan
A novel CRM1-dependent nuclear export signal in adenoviral E1A protein regulated by phosphorylation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2603-5.
2006: Koul Dimpy; Takada Yasunari; Shen Ruijun; Aggarwal Bharat B; Yung W K Alfred
PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kappaB signaling pathway in human glioma cells.
Biochemical and biophysical research communications 2006;350(2):463-71.
2006: Colman Howard; Berkey Brian A; Maor Moshe H; Groves Morris D; Schultz Christopher J; Vermeulen Sandra; Nelson Diana F; Mehta Minesh P; Yung W K Alfred;
Phase II Radiation Therapy Oncology Group trial of conventional radiation therapy followed by treatment with recombinant interferon-beta for supratentorial glioblastoma: results of RTOG 9710.
International journal of radiation oncology, biology, physics 2006;66(3):818-24.
2006: Mayes Debra A; Hu Yuanjie; Teng Yue; Siegel Eric; Wu Xiaosong; Panda Kishori; Tan Fang; Yung W K Alfred; Zhou Yi-Hong
PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene.
Cancer research 2006;66(20):9809-17.
2006: Groves Morris D; Puduvalli Vinay K; Conrad Charles A; Gilbert Mark R; Yung W K Alfred; Jaeckle Kurt; Liu Vivien; Hess Kenneth R; Aldape Kenneth D; Levin Victor A
Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status.
Journal of neuro-oncology 2006;80(1):83-90.
2006: Cloughesy Timothy F; Wen Patrick Y; Robins H Ian; Chang Susan M; Groves Morris D; Fink Karen L; Junck Larry; Schiff David; Abrey Lauren; Gilbert Mark R; Lieberman Frank; Kuhn John; DeAngelis Lisa M; Mehta Minesh; Raizer Jeff J; Yung W K Alfred; Aldape Ken; Wright John; Lamborn Kathleen R; Prados Michael D
Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(22):3651-6.
2006: Pelloski Christopher E; Lin E; Zhang Li; Yung W K Alfred; Colman Howard; Liu Juinn-Lin; Woo Shaio Y; Heimberger Amy B; Suki Dima; Prados Michael; Chang Susan; Barker Fredrick G; Fuller Gregory N; Aldape Kenneth D
Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(13):3935-41.
2006: Levin Victor A; Phuphanich Surasak; Yung W K Alfred; Forsyth Peter A; Maestro Rolando Del; Perry James R; Fuller Gregory N; Baillet Mark
Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation.
Journal of neuro-oncology 2006;78(3):295-302.
2006: Lee Ok-Hee; Fueyo Juan; Xu Jing; Yung W K Alfred; Lemoine Michael G; Lang Frederick F; Bekele B Nebiyou; Zhou Xian; Alonso Marta A; Aldape Kenneth D; Fuller Gregory N; Gomez-Manzano Candelaria
Sustained angiopoietin-2 expression disrupts vessel formation and inhibits glioma growth.
Neoplasia (New York, N.Y.) 2006;8(5):419-28.
2006: Alonso Marta M; Fueyo Juan; Yung W K Alfred; Gomez-Manzano Candelaria
E2F1 and telomerase: alliance in the dark side.
Cell cycle (Georgetown, Tex.) 2006;5(9):930-5.
2006: Levin V A; Giglio P; Puduvalli V K; Jochec J; Groves M D; Yung W K A; Hess K
Combination chemotherapy with 13-cis-retinoic acid and celecoxib in the treatment of glioblastoma multiforme.
Journal of neuro-oncology 2006;78(1):85-90.
2006: Prados Michael D; Lamborn Kathleen; Yung W K A; Jaeckle Kurt; Robins H Ian; Mehta Minesh; Fine Howard A; Wen Patrick Y; Cloughesy Timothy; Chang Susan; Nicholas M Kelly; Schiff David; Greenberg Harry; Junck Larry; Fink Karen; Hess Ken; Kuhn John;
A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.
Neuro-oncology 2006;8(2):189-93.
2006: Koul Dimpy; Shen Ruijun; Bergh Sherry; Sheng Xiaoyang; Shishodia Shishir; Lafortune Tiffany A; Lu Yiling; de Groot John F; Mills Gordon B; Yung W K Alfred
Inhibition of Akt survival pathway by a small-molecule inhibitor in human glioblastoma.
Molecular cancer therapeutics 2006;5(3):637-44.
2006: Gomez-Manzano Candelaria; Alonso Marta M; Yung W K Alfred; McCormick Frank; Curiel David T; Lang Frederick F; Jiang Hong; Bekele B Nebiyou; Zhou Xian; Alemany Ramon; Fueyo Juan
Delta-24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):556-62.
2005: Koul Dimpy; Shen Ruijun; Bergh Sherry; Lu Yiling; de Groot John F; Liu Ta Jen; Mills Gordon B; Yung W K Alfred
Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma.
Molecular cancer therapeutics 2005;4(11):1681-8.
2005: Alonso Marta M; Fueyo Juan; Shay Jerry W; Aldape Kenneth D; Jiang Hong; Lee Ok-Hee; Johnson David G; Xu Jing; Kondo Yasuko; Kanzawa Takao; Kyo Satoru; Bekele B Nebiyou; Zhou Xian; Nigro Janice; McDonald J Matthew; Yung W K Alfred; Gomez-Manzano Candelaria
Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.
Journal of the National Cancer Institute 2005;97(21):1589-600.
2005: Zhou Yi-Hong; Hess Kenneth R; Liu Longjian; Linskey Mark E; Yung W K Alfred
Modeling prognosis for patients with malignant astrocytic gliomas: quantifying the expression of multiple genetic markers and clinical variables.
Neuro-oncology 2005;7(4):485-94.
2005: Jiang Hong; Alemany Ramon; Gomez-Manzano Candelaria; Medrano Diana R; Lemoine Michael G; Olson Melissa V; Alonso Marta M; Lee Ok-Hee; Conrad Charles C; Yung W K Alfred; Fueyo Juan
Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses.
Neoplasia (New York, N.Y.) 2005;7(8):723-9.
2005: Liu Juinn-Lin; Sheng Xiaoyang; Hortobagyi Zsuzsanna K; Mao Zhenyu; Gallick Gary E; Yung W K Alfred
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
Molecular and cellular biology 2005;25(14):6211-24.
2005: de Groot John F; Liu Ta Jen; Fuller Gregory; Yung W K Alfred
The excitatory amino acid transporter-2 induces apoptosis and decreases glioma growth in vitro and in vivo.
Cancer research 2005;65(5):1934-40.
2005: Nigro Janice M; Misra Anjan; Zhang Li; Smirnov Ivan; Colman Howard; Griffin Chandi; Ozburn Natalie; Chen Mingang; Pan Edward; Koul Dimpy; Yung W K Alfred; Feuerstein Burt G; Aldape Kenneth D
Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma.
Cancer research 2005;65(5):1678-86.
2005: Conrad Charles; Miller C Ryan; Ji Yongjie; Gomez-Manzano Candeleria; Bharara Suman; McMurray John S; Lang Frederick F; Wong Franklin; Sawaya Raymond; Yung W K Alfred; Fueyo Juan
Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization.
Cancer gene therapy 2005;12(3):284-94.
2005: Zhou Yi-Hong; Wu Xiaosong; Tan Fang; Shi Yue-Xi; Glass Tricia; Liu T J; Wathen Kyle; Hess Kenneth R; Gumin Joy; Lang Frederick; Yung W K Alfred
PAX6 suppresses growth of human glioblastoma cells.
Journal of neuro-oncology 2005;71(3):223-9.
2005: Jiang Hong; Gomez-Manzano Candelaria; Alemany Ramon; Medrano Diana; Alonso Marta; Bekele B Nebiyou; Lin E; Conrad Charles C; Yung W K Alfred; Fueyo Juan
Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas.
Neoplasia (New York, N.Y.) 2005;7(1):48-56.
2004: Puduvalli Vinay K; Yung W K Alfred; Hess Kenneth R; Kuhn John G; Groves Morris D; Levin Victor A; Zwiebel James; Chang Susan M; Cloughesy Timothy F; Junck Larry; Wen Patrick; Lieberman Frank; Conrad Charles A; Gilbert Mark R; Meyers Christina A; Liu Vivien; Mehta Minesh P; Nicholas M Kelly; Prados Michael;
Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(21):4282-9.
2004: Yung W K Alfred
Current therapies for glioblastoma.
Clinical advances in hematology & oncology : H&O 2004;2(9):572-3.
2004: Wang Li-E; Bondy Melissa L; Shen Hongbing; El-Zein Randa; Aldape Kenneth; Cao Yumei; Pudavalli Vinay; Levin Victor A; Yung W K Alfred; Wei Qingyi
Polymorphisms of DNA repair genes and risk of glioma.
Cancer research 2004;64(16):5560-3.
2004: Gomez-Manzano Candelaria; Yung W K Alfred; Alemany Ramon; Fueyo Juan
Genetically modified adenoviruses against gliomas: from bench to bedside.
Neurology 2004;63(3):418-26.
2004: See Siew-Ju; Levin Victor A; Yung W-K Alfred; Hess Kenneth R; Groves Morris D
13-cis-retinoic acid in the treatment of recurrent glioblastoma multiforme.
Neuro-oncology 2004;6(3):253-8.
2004: Chang Susan M; Prados Michael D; Yung W K Alfred; Fine Howard; Junck Larry; Greenberg Harry; Robins H Ian; Mehta Minesh; Fink Karen L; Jaeckle Kurt A; Kuhn John; Hess Kenneth; Schold Clifford
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
Cancer 2004;100(8):1712-6.
2004: Gomez-Manzano Candelaria; Balague Cristina; Alemany Ramon; Lemoine Michael G; Mitlianga Paraskevi; Jiang Hong; Khan Asadullah; Alonso Marta; Lang Frederick F; Conrad Charles A; Liu Ta-Jen; Bekele B Nebiyou; Yung W K Alfred; Fueyo Juan
A novel E1A-E1B mutant adenovirus induces glioma regression in vivo.
Oncogene 2004;23(10):1821-8.
2004: Cerrato Julie A; Khan Tahira; Koul Dimpy; Lang Frederick F; Conrad Charles A; Yung W K Alfred; Liu Ta-Jen
Differential activation of the Fas/CD95 pathway by Ad-p53 in human gliomas.
International journal of oncology 2004;24(2):409-17.
2004: Prados Michael D; Yung W K A; Jaeckle Kurt A; Robins H Ian; Mehta Minesh P; Fine Howard A; Wen Patrick Y; Cloughesy Timothy F; Chang Susan M; Nicholas M Kelly; Schiff David; Greenberg Harry S; Junck Larry; Fink Karen L; Hess Kenneth R; Kuhn John;
Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.
Neuro-oncology 2004;6(1):44-54.
2004: Prados Michael D; Yung W K Alfred; Fine Howard A; Greenberg Harry S; Junck Larry; Chang Susan M; Nicholas M Kelly; Robins H Ian; Mehta Minesh P; Fink Karen L; Jaeckle Kurt A; Kuhn John; Hess Kenneth R; Schold S Clifford;
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
Neuro-oncology 2004;6(1):33-7.
2003: Lu Yiling; Yu Qinghua; Liu Jue Hui; Zhang Jinyi; Wang Hongwei; Koul Dimpy; McMurray John S; Fang Xianjun; Yung W K Alfred; Siminovitch Kathy A; Mills Gordon B
Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.
The Journal of biological chemistry 2003;278(41):40057-66.
2003: Dabaja Bouthaina S; McLaughlin Peter; Ha Chul S; Pro Barbara; Meyers Christina A; Seabrooke Lee F; Wilder Richard B; Kyritsis Athanassios P; Preti H Alejandro; Yung W K Alfred; Levin Victor; Cabanillas Fernando; Cox James D
Primary central nervous system lymphoma: Phase I evaluation of infusional bromodeoxyuridine with whole brain accelerated fractionation radiation therapy after chemotherapy.
Cancer 2003;98(5):1021-8.
2003: Zhou Yi-Hong; Tan Fang; Hess Kenneth R; Yung W K Alfred
The expression of PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: relationship to tumor grade and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3369-75.
2003: Lang Frederick F; Bruner Janet M; Fuller Gregory N; Aldape Kenneth; Prados Michael D; Chang Susan; Berger Mitchel S; McDermott Michael W; Kunwar Sandeep M; Junck Larry R; Chandler William; Zwiebel James A; Kaplan Richard S; Yung W K Alfred
Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(13):2508-18.
2003: Jaeckle Kurt A; Hess Kenneth R; Yung W K Alfred; Greenberg Harry; Fine Howard; Schiff David; Pollack Ian F; Kuhn John; Fink Karen; Mehta Minesh; Cloughesy Timothy; Nicholas M Kelly; Chang Susan; Prados Michael;
Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(12):2305-11.
2003: Fueyo Juan; Alemany Ramon; Gomez-Manzano Candelaria; Fuller Gregory N; Khan Asadullah; Conrad Charles A; Liu Ta-Jen; Jiang Hong; Lemoine Michael G; Suzuki Kaori; Sawaya Raymond; Curiel David T; Yung W K Alfred; Lang Frederick F
Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway.
Journal of the National Cancer Institute 2003;95(9):652-60.
2003: Levin Victor A; Hess Kenneth R; Choucair Ali; Flynn Patrick J; Jaeckle Kurt A; Kyritsis Athanassios P; Yung W K Alfred; Prados Michael D; Bruner Janet M; Ictech Sandra; Gleason Mary Jo; Kim Hyung-Woo
Phase III randomized study of postradiotherapy chemotherapy with combination alpha-difluoromethylornithine-PCV versus PCV for anaplastic gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):981-90.
2003: Gomez-Manzano Candelaria; Fueyo Juan; Jiang Hong; Glass Tricia L; Lee Ho-Young; Hu Min; Liu Juinn-Lin; Jasti Sushma L; Liu Ta-Jen; Conrad Charles A; Yung W K Alfred
Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis.
Annals of neurology 2003;53(1):109-17.
2003: Puduvalli Vinay K; Hashmi Masood; McAllister Leslie D; Levin Victor A; Hess Kenneth R; Prados Michael; Jaeckle Kurt A; Yung W K Alfred; Buys Saundra S; Bruner Janet M; Townsend Jeannette J; Davis Richard; Sawaya Raymond; Kyritsis Athanassios P
Anaplastic oligodendrogliomas: prognostic factors for tumor recurrence and survival.
Oncology 2003;65(3):259-66.
2002: Zhou Yi-Hong; Zheng Jessica B; Gu Xun; Saunders Grady F; Yung W-K Alfred
Novel PAX6 binding sites in the human genome and the role of repetitive elements in the evolution of gene regulation.
Genome research 2002;12(11):1716-22.
2002: Lang Frederick F; Gilbert Mark R; Puduvalli Vinay K; Weinberg Jeffrey; Levin Victor A; Yung W K Alfred; Sawaya Raymond; Fuller Gregory N; Conrad Charles A
Toward better early-phase brain tumor clinical trials: a reappraisal of current methods and proposals for future strategies.
Neuro-oncology 2002;4(4):268-77.
2002: Koul Dimpy; Shen Ruijun; Garyali Anil; Ke L D; Liu Ta-Jen; Yung W K Alfred
MMAC/PTEN tumor suppressor gene regulates vascular endothelial growth factor-mediated angiogenesis in prostate cancer.
International journal of oncology 2002;21(3):469-75.
2002: Levin V A; Yung W K A; Bruner J; Kyritsis A; Leeds N; Gleason M J; Hess K R; Meyers C A; Ictech S A; Chang E; Maor M H
Phase II study of accelerated fractionation radiation therapy with carboplatin followed by PCV chemotherapy for the treatment of anaplastic gliomas.
International journal of radiation oncology, biology, physics 2002;53(1):58-66.
2002: Koul Dimpy; Jasser Samar A; Lu Yiling; Davies Michael A; Shen Ruijun; Shi Yuexi; Mills Gordon B; Yung W K Alfred
Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.
Oncogene 2002;21(15):2357-64.
2002: Robins H Ian; Chang Susan M; Prados Michael D; Yung W K Alfred; Hess Kenneth; Schiff David; Greenberg Harry; Fink Karen; Nicolas Kelly; Kuhn John G; Cloughesy Timothy; Junck Larry; Mehta Minesh
A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study.
Neuro-oncology 2002;4(2):109-14.
2002: Ke Li Dao; Shi Yue-Xi; Yung W K Alfred
VEGF(121), VEGF(165) overexpression enhances tumorigenicity in U251 MG but not in NG-1 glioma cells.
Cancer research 2002;62(6):1854-61.
2002: Sheng Xiaoyang; Koul Dimpy; Liu Juinn-Lin; Liu Ta-Jen; Yung W K Alfred
Promoter analysis of tumor suppressor gene PTEN: identification of minimum promoter region.
Biochemical and biophysical research communications 2002;292(2):422-6.
2002: Groves Morris D; Puduvalli Vinay K; Hess Kenneth R; Jaeckle Kurt A; Peterson Pamela; Yung W K Alfred; Levin Victor A
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(5):1383-8.
2002: Fuller Gregory N; Hess Kenneth R; Rhee Chang Hun; Yung W K Alfred; Sawaya Raymond A; Bruner Janet M; Zhang Wei
Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene expression profiles parallels morphology-based classification, correlates with survival, and reveals clinically-relevant novel glioma subsets.
Brain pathology (Zurich, Switzerland) 2002;12(1):108-16.
2002: Kunschner Lara J; Fine Howard; Hess Kenneth; Jaeckle Kurt; Kyritsis Athanassios P; Yung W K Alfred
CI-980 for the treatment of recurrent or progressive malignant gliomas: national central nervous system consortium phase I-II evaluation of CI-980.
Cancer investigation 2002;20(7-8):948-54.
2001: Koul D; Parthasarathy R; Shen R; Davies M A; Jasser S A; Chintala S K; Rao J S; Sun Y; Benvenisite E N; Liu T J; Yung W K
Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.
Oncogene 2001;20(46):6669-78.
2001: Gomez-Manzano C; Mitlianga P; Fueyo J; Lee H Y; Hu M; Spurgers K B; Glass T L; Koul D; Liu T J; McDonnell T J; Yung W K
Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2.
Cancer research 2001;61(18):6693-7.
2001: Yung W K
Future directions for temozolomide therapy.
Seminars in oncology 2001;28(4 Suppl 13):43-6.
2001: Mohanam S; Jasti S L; Kondraganti S R; Chandrasekar N; Kin Y; Fuller G N; Lakka S S; Kyritsis A P; Dinh D H; Olivero W C; Gujrati M; Yung W K; Rao J S
Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2519-26.
2001: Kunschner L J; Kuttesch J; Hess K; Yung W K
Survival and recurrence factors in adult medulloblastoma: the M.D. Anderson Cancer Center experience from 1978 to 1998.
Neuro-oncology 2001;3(3):167-73.
2001: Lakka S S; Rajagopal R; Rajan M K; Mohan P M; Adachi Y; Dinh D H; Olivero W C; Gujrati M; Ali-Osman F; Roth J A; Yung W K; Kyritsis A P; Rao J S
Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(4):1087-93.
2001: Cerrato J A; Yung W K; Liu T J
Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis.
Neuro-oncology 2001;3(2):113-22.
2001: Koul D; Yao Y; Abbruzzese J L; Yung W K; Reddy S A
Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway.
The Journal of biological chemistry 2001;276(14):11402-8.
2001: Fueyo J; Gomez-Manzano C; Liu T J; Yung W K
Delivery of cell cycle genes to block astrocytoma growth.
Journal of neuro-oncology 2001;51(3):277-87.
2001: Mitlianga P G; Kyritsis A P; Gomez-Manzano C; Lemoine M G; Hu M; Liu T J; Yung W K; Fueyo J
Co-expression of E2F-2 enhances the p53 anti-cancer effect in human glioma cells.
International journal of oncology 2001;18(2):343-7.
2000: Yung W K; Albright R E; Olson J; Fredericks R; Fink K; Prados M D; Brada M; Spence A; Hohl R J; Shapiro W; Glantz M; Greenberg H; Selker R G; Vick N A; Rampling R; Friedman H; Phillips P; Bruner J; Yue N; Osoba D; Zaknoen S; Levin V A
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse.
British journal of cancer 2000;83(5):588-93.
2000: Glass T L; Liu T J; Yung W K
Inhibition of cell growth in human glioblastoma cell lines by farnesyltransferase inhibitor SCH66336.
Neuro-oncology 2000;2(3):151-8.
2000: Ke L D; Shi Y X; Im S A; Chen X; Yung W K
The relevance of cell proliferation, vascular endothelial growth factor, and basic fibroblast growth factor production to angiogenesis and tumorigenicity in human glioma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(6):2562-72.
2000: Yung W K
Temozolomide in malignant gliomas.
Seminars in oncology 2000;27(3 Suppl 6):27-34.
2000: Ke L D; Chen Z; Yung W K
A reliability test of standard-based quantitative PCR: exogenous vs endogenous standards.
Molecular and cellular probes 2000;14(2):127-35.
2000: Meyers C A; Hess K R; Yung W K; Levin V A
Cognitive function as a predictor of survival in patients with recurrent malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(3):646-50.
2000: Fueyo J; Gomez-Manzano C; Alemany R; Lee P S; McDonnell T J; Mitlianga P; Shi Y X; Levin V A; Yung W K; Kyritsis A P
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.
Oncogene 2000;19(1):2-12.
2000: Lakka S S; Jasti S L; Kyritsis A P; Yung W K; Ali-Osman F; Nicolson G L; Rao J S
Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades.
Clinical & experimental metastasis 2000;18(3):245-52.
1999: Chintala S K; Kyritsis A P; Mohan P M; Mohanam S; Sawaya R; Gokslan Z; Yung W K; Steck P; Uhm J H; Aggarwal B B; Rao J S
Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.
Molecular carcinogenesis 1999;26(4):274-85.
1999: Lang F F; Yung W K; Sawaya R; Tofilon P J
Adenovirus-mediated p53 gene therapy for human gliomas.
Neurosurgery 1999;45(5):1093-104.
1999: Hess K R; Wong E T; Jaeckle K A; Kyritsis A P; Levin V A; Prados M D; Yung W K
Response and progression in recurrent malignant glioma.
Neuro-oncology 1999;1(4):282-8.
1999: Alemany R; Gomez-Manzano C; Balagué C; Yung W K; Curiel D T; Kyritsis A P; Fueyo J
Gene therapy for gliomas: molecular targets, adenoviral vectors, and oncolytic adenoviruses.
Experimental cell research 1999;252(1):1-12.
1999: Yung W K; Prados M D; Yaya-Tur R; Rosenfeld S S; Brada M; Friedman H S; Albright R; Olson J; Chang S M; O'Neill A M; Friedman A H; Bruner J; Yue N; Dugan M; Zaknoen S; Levin V A
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(9):2762-71.
1999: Fuller G N; Rhee C H; Hess K R; Caskey L S; Wang R; Bruner J M; Yung W K; Zhang W
Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling.
Cancer research 1999;59(17):4228-32.
1999: Wong E T; Hess K R; Gleason M J; Jaeckle K A; Kyritsis A P; Prados M D; Levin V A; Yung W K
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(8):2572-8.
1999: Groves M D; Maor M H; Meyers C; Kyritsis A P; Jaeckle K A; Yung W K; Sawaya R E; Hess K; Bruner J M; Peterson P; Levin V A
A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme.
International journal of radiation oncology, biology, physics 1999;45(1):127-35.
1999: Tang P; Jasser S A; Sung J C; Shi Y; Steck P A; Yung W K
Transforming growth factor-alpha antisense vectors can inhibit glioma cell growth.
Journal of neuro-oncology 1999;43(2):127-35.
1999: Davies M A; Koul D; Dhesi H; Berman R; McDonnell T J; McConkey D; Yung W K; Steck P A
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN.
Cancer research 1999;59(11):2551-6.
1999: Sano T; Lin H; Chen X; Langford L A; Koul D; Bondy M L; Hess K R; Myers J N; Hong Y K; Yung W K; Steck P A
Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis.
Cancer research 1999;59(8):1820-4.
1999: Fueyo J; Gomez-Manzano C; Yung W K; Kyritsis A P
Targeting in gene therapy for gliomas.
Archives of neurology 1999;56(4):445-8.
1999: Im S A; Gomez-Manzano C; Fueyo J; Liu T J; Ke L D; Kim J S; Lee H Y; Steck P A; Kyritsis A P; Yung W K
Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo.
Cancer research 1999;59(4):895-900.
1999: Steck P A; Lin H; Langford L A; Jasser S A; Koul D; Yung W K; Pershouse M A
Functional and molecular analyses of 10q deletions in human gliomas.
Genes, chromosomes & cancer 1999;24(2):135-43.
1999: Gomez-Manzano C; Fueyo J; Alameda F; Kyritsis A P; Yung W K
Gene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis.
International journal of molecular medicine 1999;3(1):81-5.
1998: Sigurdson A J; Bondy M L; Hess K R; Toms S A; Kyritsis A P; Gu J; Wang L E; Wang X; Adatto P; Bruner J L; Yung W K; Levin V A; Wei Q
Gamma-ray mutagen sensitivity and survival in patients with glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(12):3031-5.
1998: Davies M A; Lu Y; Sano T; Fang X; Tang P; LaPushin R; Koul D; Bookstein R; Stokoe D; Yung W K; Mills G B; Steck P A
Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.
Cancer research 1998;58(23):5285-90.
1998: Fueyo J; Gomez-Manzano C; Yung W K; Kyritsis A P
The functional role of tumor suppressor genes in gliomas: clues for future therapeutic strategies.
Neurology 1998;51(5):1250-5.
1998: Lin H; Bondy M L; Langford L A; Hess K R; Delclos G L; Wu X; Chan W; Pershouse M A; Yung W K; Steck P A
Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2447-54.
1998: Lang F F; Yung W K; Raju U; Libunao F; Terry N H; Tofilon P J
Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene.
Journal of neurosurgery 1998;89(1):125-32.
1998: Fueyo J; Gomez-Manzano C; Yung W K; Liu T J; Alemany R; McDonnell T J; Shi X; Rao J S; Levin V A; Kyritsis A P
Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo.
Nature medicine 1998;4(6):685-90.
1998: Ke L D; Fueyo J; Chen X; Steck P A; Shi Y X; Im S A; Yung W K
A novel approach to glioma gene therapy: down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes.
International journal of oncology 1998;12(6):1391-6.
1998: Fueyo J; Gomez-Manzano C; Yung W K; Liu T J; Alemany R; Bruner J M; Chintala S K; Rao J S; Levin V A; Kyritsis A P
Suppression of human glioma growth by adenovirus-mediated Rb gene transfer.
Neurology 1998;50(5):1307-15.
1998: Ligon A H; Pershouse M A; Jasser S; Hong Y K; Yung W K; Steck P A
Differentially expressed gene products in glioblastoma cells suppressed for tumorigenicity.
Journal of neurovirology 1998;4(2):217-26.
1998: Hess K R; Wong E T; Yung W K
Assessing response to chemotherapy in malignant glioma: the role of steroids.
Neurology 1998;50(4):1197; disscussion 1197-8.
1998: Wong E T; Jackson E F; Hess K R; Schomer D F; Hazle J D; Kyritsis A P; Jaeckle K A; Yung W K; Levin V A; Leeds N E
Correlation between dynamic MRI and outcome in patients with malignant gliomas.
Neurology 1998;50(3):777-81.
1998: Fueyo J; Gomez-Manzano C; Puduvalli V K; Martin-Duque P; Perez-Soler R; Levin V A; Yung W K; Kyritsis A P
Adenovirus-mediated p16 transfer to glioma cells induces G1 arrest and protects from paclitaxel and topotecan: implications for therapy.
International journal of oncology 1998;12(3):665-9.
1997: Tang P; Steck P A; Yung W K
The autocrine loop of TGF-alpha/EGFR and brain tumors.
Journal of neuro-oncology 1997;35(3):303-14.
1997: Teng D H; Hu R; Lin H; Davis T; Iliev D; Frye C; Swedlund B; Hansen K L; Vinson V L; Gumpper K L; Ellis L; El-Naggar A; Frazier M; Jasser S; Langford L A; Lee J; Mills G B; Pershouse M A; Pollack R E; Tornos C; Troncoso P; Yung W K; Fujii G; Berson A; Steck P A
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.
Cancer research 1997;57(23):5221-5.
1997: Pershouse M A; Ligon A H; Pereira-Smith O M; Killary A M; Yung W K; Steck P A
Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells.
Genes, chromosomes & cancer 1997;20(3):260-7.
1997: Chintala S K; Fueyo J; Gomez-Manzano C; Venkaiah B; Bjerkvig R; Yung W K; Sawaya R; Kyritsis A P; Rao J S
Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro.
Oncogene 1997;15(17):2049-57.
1997: Kaba S E; Kyritsis A P; Conrad C; Gleason M J; Newman R; Levin V A; Yung W K
The treatment of recurrent cerebral gliomas with all-trans-retinoic acid (tretinoin).
Journal of neuro-oncology 1997;34(2):145-51.
1997: Gomez-Manzano C; Fueyo J; Kyritsis A P; McDonnell T J; Steck P A; Levin V A; Yung W K
Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.
Journal of the National Cancer Institute 1997;89(14):1036-44.
1997: Wei Q; Bondy M L; Mao L; Gaun Y; Cheng L; Cunningham J; Fan Y; Bruner J M; Yung W K; Levin V A; Kyritsis A P
Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas.
Cancer research 1997;57(9):1673-7.
1997: Steck P A; Pershouse M A; Jasser S A; Yung W K; Lin H; Ligon A H; Langford L A; Baumgard M L; Hattier T; Davis T; Frye C; Hu R; Swedlund B; Teng D H; Tavtigian S V
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.
Nature genetics 1997;15(4):356-62.
1997: Ligon A H; Pershouse M A; Jasser S A; Yung W K; Steck P A
Identification of a novel gene product, RIG, that is down-regulated in human glioblastoma.
Oncogene 1997;14(9):1075-81.
1997: Kaba S E; Kyritsis A P; Hess K; Yung W K; Mercier R; Dakhil S; Jaeckle K A; Levin V A
TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(3):1063-70.
1997: Kaba S E; DeMonte F; Bruner J M; Kyritsis A P; Jaeckle K A; Levin V; Yung W K
The treatment of recurrent unresectable and malignant meningiomas with interferon alpha-2B.
Neurosurgery 1997;40(2):271-5.
1997: Pershouse M A; El-Naggar A K; Hurr K; Lin H; Yung W K; Steck P A
Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma.
Oncogene 1997;14(3):369-73.
1996: Yung W K; Kyritsis A P; Gleason M J; Levin V A
Treatment of recurrent malignant gliomas with high-dose 13-cis-retinoic acid.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(12):1931-5.
1996: Kyritsis A P; Yung W K; Jaeckle K A; Bruner J; Gleason M J; Ictech S E; Flowers A; Levin V A
Combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas.
Neurosurgery 1996;39(5):921-6.
1996: Fueyo J; Gomez-Manzano C; Bruner J M; Saito Y; Zhang B; Zhang W; Levin V A; Yung W K; Kyritsis A P
Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas.
Oncogene 1996;13(8):1615-9.
1996: Kaba S E; Langford L A; Yung W K; Kyritsis A P
Resolution of recurrent malignant ganglioglioma after treatment with cis-retinoic acid.
Journal of neuro-oncology 1996;30(1):55-60.
1996: Gomez-Manzano C; Fueyo J; Kyritsis A P; Steck P A; Roth J A; McDonnell T J; Steck K D; Levin V A; Yung W K
Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis.
Cancer research 1996;56(4):694-9.
1996: Fueyo J; Gomez-Manzano C; Yung W K; Clayman G L; Liu T J; Bruner J; Levin V A; Kyritsis A P
Adenovirus-mediated p16/CDKN2 gene transfer induces growth arrest and modifies the transformed phenotype of glioma cells.
Oncogene 1996;12(1):103-10.
1995: Kyritsis A P; Bondy M L; Hess K R; Cunningham J E; Zhu D; Amos C J; Yung W K; Levin V A; Bruner J M
Prognostic significance of p53 immunoreactivity in patients with glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1617-22.
1995: Fueyo J; Gomez-Manzano C; Yung W K; Zhang W; Lee P S; Majumder S; Perhouse M; Levin V A; Kyritsis A P
A frequent polymorphism in exon 1 of the p16/CDKN2 gene.
Molecular and cellular probes 1995;9(6):465-6.
1995: Levin V A; Maor M H; Thall P F; Yung W K; Bruner J; Sawaya R; Kyritsis A P; Leeds N; Woo S; Rodriguez L
Phase II study of accelerated fractionation radiation therapy with carboplatin followed by vincristine chemotherapy for the treatment of glioblastoma multiforme.
International journal of radiation oncology, biology, physics 1995;33(2):357-64.
1995: Van Tassel P; Bruner J M; Maor M H; Leeds N E; Gleason M J; Yung W K; Levin V A
MR of toxic effects of accelerated fractionation radiation therapy and carboplatin chemotherapy for malignant gliomas.
AJNR. American journal of neuroradiology 1995;16(4):715-26.
1995: Steck P A; Ligon A H; Cheong P; Yung W K; Pershouse M A
Two tumor suppressive loci on chromosome 10 involved in human glioblastomas.
Genes, chromosomes & cancer 1995;12(4):255-61.
1993: Pershouse M A; Stubblefield E; Hadi A; Killary A M; Yung W K; Steck P A
Analysis of the functional role of chromosome 10 loss in human glioblastomas.
Cancer research 1993;53(20):5043-50.
1993: Kyritsis A P; Yung W K; Bruner J; Gleason M J; Levin V A
The treatment of anaplastic oligodendrogliomas and mixed gliomas.
Neurosurgery 1993;32(3):365-70; discussion 371.
1993: Meyers C A; Yung W K
Delayed neurotoxicity of intraventricular interleukin-2: a case report.
Journal of neuro-oncology 1993;15(3):265-7.
1992: Levin V A; Prados M D; Yung W K; Gleason M J; Ictech S; Malec M
Treatment of recurrent gliomas with eflornithine.
Journal of the National Cancer Institute 1992;84(18):1432-7.
1992: Yung W K; Janus T J; Maor M; Feun L G
Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas.
Journal of neuro-oncology 1992;12(2):131-5.
1991: Yung W K; Prados M; Levin V A; Fetell M R; Bennett J; Mahaley M S; Salcman M; Etcubanas E
Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: a phase I/II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(11):1945-9.
1991: Yung W K; Mechtler L; Gleason M J
Intravenous carboplatin for recurrent malignant glioma: a phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(5):860-4.
1991: Garden A S; Maor M H; Yung W K; Bruner J M; Woo S Y; Moser R P; Lee Y Y
Outcome and patterns of failure following limited-volume irradiation for malignant astrocytomas.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1991;20(2):99-110.
1990: Newton L K; Yung W K; Pettigrew L C; Steck P A
Growth regulatory activities of endothelial extracellular matrix: mediation by transforming growth factor-beta.
Experimental cell research 1990;190(1):127-32.
1990: Yung W K; Castellanos A M; Van Tassel P; Moser R P; Marcus S G
A pilot study of recombinant interferon beta (IFN-beta ser) in patients with recurrent glioma.
Journal of neuro-oncology 1990;9(1):29-34.
1989: Maria B L; Steck P A; Yung W K; Milici A; Bruner J M; Pathak S; Becker F F
The modulation of astrocytic differentiation in cells derived from a medulloblastoma surgical specimen.
Journal of neuro-oncology 1989;7(4):329-38.
1989: Yung W K; Harris M I; Bruner J M; Feun L G
Intravenous BCNU and AZQ in patients with recurrent malignant gliomas.
Journal of neuro-oncology 1989;7(3):237-40.
1989: Steck P A; Moser R P; Bruner J M; Liang L; Freidman A N; Hwang T L; Yung W K
Altered expression and distribution of heparan sulfate proteoglycans in human gliomas.
Cancer research 1989;49(8):2096-103.
1989: Yung W K; Lotan R; Lee P; Lotan D; Steck P A
Modulation of growth and epidermal growth factor receptor activity by retinoic acid in human glioma cells.
Cancer research 1989;49(4):1014-9.
1989: Yung W K
In vitro chemosensitivity testing and its clinical application in human gliomas.
Neurosurgical review 1989;12(3):197-203.
1988: McLaughlin P; Velasquez W S; Redman J R; Yung W K; Hagemeister F B; Rodriguez M A; Cabanillas F
Chemotherapy with dexamethasone, high-dose cytarabine, and cisplatin for parenchymal brain lymphoma.
Journal of the National Cancer Institute 1988;80(17):1408-12.
1988: Steck P A; Lee P; Hung M C; Yung W K
Expression of an altered epidermal growth factor receptor by human glioblastoma cells.
Cancer research 1988;48(19):5433-9.
1987: Yung W K; Steck P A; Kelleher P J; Moser R P; Rosenblum M G
Growth inhibitory effect of recombinant alpha and beta interferon on human glioma cells.
Journal of neuro-oncology 1987;5(4):323-30.

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