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Alfred Yung

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W K Alfred Yung
From GWAS risk foci to glioma molecular subclass.
W K Alfred Yung
Year brings higher impact factor, more submissions for Neuro-Oncology.
Brian M Alexander; Walter J Curran; Bernadine A Donahue; Howard A Fine; Alan C Hartford; Kevin J Kerlin; Ray S Richards; Ivo W Tremont; Meihua Wang; W K Alfred Yung; Minesh Mehta
A phase II study of conventional radiation therapy and thalidomide for supratentorial, newly-diagnosed glioblastoma (RTOG 9806).

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All Publications

2013: W K Alfred Yung
From GWAS risk foci to glioma molecular subclass.
Neuro-oncology 2013;15(5):513-4.
2013: W K Alfred Yung
Year brings higher impact factor, more submissions for Neuro-Oncology.
Neuro-oncology 2013;15(1):1-3.
2013: Brian M Alexander; Walter J Curran; Bernadine A Donahue; Howard A Fine; Alan C Hartford; Kevin J Kerlin; Ray S Richards; Ivo W Tremont; Meihua Wang; W K Alfred Yung; Minesh Mehta
A phase II study of conventional radiation therapy and thalidomide for supratentorial, newly-diagnosed glioblastoma (RTOG 9806).
Journal of neuro-oncology 2013;111(1):33-9.
2012: Eudocia Q Lee; Victor A Levin; Frank Lieberman; Minesh Mehta; Michael D Prados; H Ian Robins; John J Wright; W K Alfred Yung; Lauren Abrey; Kenneth Aldape; Susan M Chang; Timothy F Cloughesy; Janet E Dancey; Lisa M DeAngelis; Jan Drappatz; Mark R Gilbert; John Kuhn; Kathleen R Lamborn; Patrick Y Wen
Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02.
Neuro-oncology 2012;14(12):1511-8.
2012: Eudocia Q Lee; Frank S Lieberman; Renee M McGovern; Michael D Prados; Vinay K Puduvalli; Joel M Reid; H Ian Robins; Matthew M Ames; Susan M Chang; Timothy F Cloughesy; Serena Desideri; Jan Drappatz; Igor Espinoza-Delgado; Mark R Gilbert; John G Kuhn; Kathleen R Lamborn; Andrew B Lassman; Jihong Xu; Xiabu Ye; W K Alfred Yung; Patrick Y Wen
Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(21):6032-9.
2012: Brett J Theeler; W K Alfred Yung; Gregory N Fuller; John F de Groot
Moving toward molecular classification of diffuse gliomas in adults.
Neurology 2012;79(18):1917-26.
2012: W K Alfred Yung
New impact factor reflects increased quality.
Neuro-oncology 2012;14(9):1115.
2012: Pierre Giglio; Mark R Gilbert; Morris D Groves; Kenneth R Hess; Sandra E Ictech; Sanghee L Kang; Victor A Levin; Vivien Liu; Monica Loghin; Latif Shooshtari Nasrin; Charles A Conrad; John de Groot; Megha Dhamne; W K Alfred Yung; Vinay K Puduvalli
Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma.
Cancer 2012;118(14):3599-606.
2012: W K Alfred Yung
The value of cell line validation.
Neuro-oncology 2012;14(6):675.
2012: David A Reardon; Jane Xia; Kenneth D Aldape; Wei Chen; Timothy Cloughesy; Charles A Conrad; Clifford DiLea; Margaret Dugan; Henry S Friedman; Jerry Huang; William Mietlowski; Paul Mischel; Michael D Prados; W K Alfred Yung
Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients.
Cancer chemotherapy and pharmacology 2012;69(6):1507-18.
2012: Jun Yao; Ying Yuan; W K Alfred Yung; Li Zhang; Qi Zhao; Xiaoming Liu; John N Weinstein
Identification of common prognostic gene expression signatures with biological meanings from microarray gene expression datasets.
PloS one 2012;7(9):e45894.
2011: Nu Zhang; Wen-Tai Chiu; Howard Colman; Aihua Gong; Xi He; He Huang; Hsueh-Te Lee; Mingguang Liu; René H Medema; Raymond Sawaya; Yong Wang; Ping Wei; Keping Xie; Jianfei Xue; W K Alfred Yung; Suyun Huang
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis.
Cancer cell 2011;20(4):427-42.
2011: Jennifer L Clarke; Michele M Ennis; Lauren Abrey; Kenneth Aldape; Susan M Chang; Timothy F Cloughesy; Lisa M Deangelis; Howard A Fine; Mark R Gilbert; John Kuhn; Kathleen R Lamborn; Frank S Lieberman; Minesh Mehta; Michael D Prados; H Ian Robins; Patrick Y Wen; W K Alfred Yung
Is surgery at progression a prognostic marker for improved 6-month progression-free survival or overall survival for patients with recurrent glioblastoma?
Neuro-oncology 2011;13(10):1118-24.
2011: Jennifer M Atkinson; Nidal Boulos; Angel Montero Carcaboso; Chris Eden; David W Ellison; Clementine Féau; Amar Gajjar; Paul Gibson; R Kiplin Guy; Robert A Johnson; Dimpy Koul; Tanya A Kranenburg; Kumarasamypet M Mohankumar; Timothy Phoenix; Helen M Poppleton; Waldemar Priebe; Anang A Shelat; Clinton F Stewart; Yiai Tong; Karen Wright; W K Alfred Yung; Liqin Zhu; Leggy Arnold; Richard J Gilbertson
An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.
Cancer cell 2011;20(3):384-99.
2011: W K Alfred Yung
New impact factor number reflects sustained and enhanced growth.
Neuro-oncology 2011;13(9):925.
2011: Patrick Y Wen; W K Alfred Yung; Tracy T Batchelor; Bruce A Chabner; Susan M Chang; Timothy F Cloughesy; John F de Groot; Keith Flaherty; Evanthia Galanis; Mark R Gilbert; Stuart A Grossman; Minesh Mehta; David Peereboom; Michael D Prados; David A Reardon; David Schiff; Gary K Schwartz; Lisa M DeAngelis
It is time to include patients with brain tumors in phase I trials in oncology.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(24):3211-3.
2011: Malika L Siker; Luis Souhami; Meihua Wang; W K Alfred Yung; Arnab Chakravarti; Christopher T Coughlin; Walter J. CURRAN; John Del Rowe; Jeff M Michalski; Diana F Nelson; Kimberly Porter; Minesh Mehta
Age as an independent prognostic factor in patients with glioblastoma: a Radiation Therapy Oncology Group and American College of Surgeons National Cancer Data Base comparison.
Journal of neuro-oncology 2011;104(1):351-6.
2011: Su Guan; Peter Houghton; Tiffany A Lafortune; Ruijun Shen; Ningyi Tiao; W K Alfred Yung; Dimpy Koul
Establishment and characterization of clinically relevant models of ependymoma: a true challenge for targeted therapy.
Neuro-oncology 2011;13(7):748-58.
2011: John F de Groot; Lisa De Angelis; Mark R Gilbert; Edward F Jackson; Kathleen R Lamborn; Andrew B Lassman; Frank S Lieberman; Minesh Mehta; Michael D Prados; H Ian Robins; Kenneth Aldape; Susan M Chang; Alice Chen; Timothy F Cloughesy; Jun Yao; W K Alfred Yung; Patrick Y Wen
Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(19):2689-95.
2011: Jeffrey S Wefel; Timothy Cloughesy; James L Zazzali; Maoxia Zheng; Michael Prados; Patrick Y Wen; Tom Mikkelsen; David Schiff; Lauren E Abrey; W K Alfred Yung; Nina Paleologos; Martin K Nicholas; Randy Jensen; James Vredenburgh; Asha Das; Henry S Friedman
Neurocognitive function in patients with recurrent glioblastoma treated with bevacizumab.
Neuro-oncology 2011;13(6):660-8.
2011: Yong-Wan Kim; Ta Jen Liu; Dimpy Koul; Ningyi Tiao; Abdullah H Feroze; Jing Wang; Garth Powis; W K Alfred Yung
Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM.
Neuro-oncology 2011;13(4):367-75.
2011: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung
Advances in translational research in neuro-oncology.
Archives of neurology 2011;68(3):303-8.
2011: Juinn-Lin Liu; Zhenyu Mao; Gary E Gallick; W K Alfred Yung
AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor.
Neuro-oncology 2011;13(2):184-94.
2011: Michael Prados; Timothy F Cloughesy; Meghna Samant; Liang Fang; Patrick Y Wen; Tom Mikkelsen; David Schiff; Lauren E Abrey; W K Alfred Yung; Nina Paleologos; M Kelly Nicholas; Randy Jensen; James Vredenburgh; Asha Das; Henry S Friedman
Response as a predictor of survival in patients with recurrent glioblastoma treated with bevacizumab.
Neuro-oncology 2011;13(1):143-51.
2010: W K Alfred Yung
The problem with cell phones...or maybe not.
Neuro-oncology 2010;12(11):1087.
2010: Mark R Gilbert; Javier Gonzalez; Kathy Hunter; Kenneth Hess; Pierre Giglio; Eric Chang; Vinay Puduvalli; Morris D Groves; Latif Shooshtari Nasrin; Charles Conrad; Victor Levin; Shiao Woo; Anita Mahajan; John de Groot; W K Alfred Yung
A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma.
Neuro-oncology 2010;12(11):1167-72.
2010: W K Alfred Yung; James J Vredenburgh; Timothy F Cloughesy; Phioanh Nghiemphu; Barbara Klencke; Mark R Gilbert; David A Reardon; Michael D Prados
Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study.
Neuro-oncology 2010;12(10):1061-70.
2010: Dimpy Koul; Ruijun Shen; Yong-Wan Kim; Yasuko Kondo; Yiling Lu; James Bankson; Sabrina M Ronen; D Lynn Kirkpatrick; Garth Powis; W K Alfred Yung
Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma.
Neuro-oncology 2010;12(6):559-69.
2010: W K Alfred Yung
Tumor stem cells, notch, and the news.
Neuro-oncology 2010;12(2):115.
2010: James J Vredenburgh; Timothy F Cloughesy; Meghna Samant; Michael Prados; Patrick Y Wen; Tom Mikkelsen; David Schiff; Lauren E Abrey; W K Alfred Yung; Nina Paleologos; Martin K Nicholas; Randy Jensen; Asha Das; Henry S Friedman
Corticosteroid use in patients with glioblastoma at first or second relapse treated with bevacizumab in the BRAIN study.
The oncologist 2010;15(12):1329-34.
2010: Jeffrey J Raizer; Lauren E Abrey; Andrew B Lassman; Susan M Chang; Kathleen R Lamborn; John Kuhn; W K Alfred Yung; Mark R Gilbert; Kenneth A Aldape; Patrick Y Wen; Howard A Fine; Minesh Mehta; Lisa De Angelis; Frank Lieberman; Timothy F Cloughesy; H Ian Robins; Janet Dancey; Michael D Prados
A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy.
Neuro-oncology 2010;12(1):95-103.
2010: Jeffrey J Raizer; Lauren E Abrey; Andrew B Lassman; Susan M Chang; Kathleen R Lamborn; John Kuhn; W K Alfred Yung; Mark R Gilbert; Kenneth Aldape; Patrick Y Wen; Howard A Fine; Minesh Mehta; Lisa De Angelis; Frank Lieberman; Timothy F Cloughesy; H Ian Robins; Janet Dancey; Michael D Prados
A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas.
Neuro-oncology 2010;12(1):87-94.
2010: Andrew D Norden; Jeffrey J Raizer; Lauren E Abrey; Kathleen R Lamborn; Andrew B Lassman; Susan M Chang; W K Alfred Yung; Mark R Gilbert; Howard A Fine; Minesh Mehta; Lisa De Angelis; Timothy F Cloughesy; H Ian Robins; Kenneth Aldape; Janet Dancey; Michael D Prados; Frank Lieberman; Patrick Y Wen
Phase II trials of erlotinib or gefitinib in patients with recurrent meningioma.
Journal of neuro-oncology 2010;96(2):211-7.
2009: Patrick Y Wen; W K Alfred Yung; Kathleen R Lamborn; Andrew D Norden; Timothy F Cloughesy; Lauren E Abrey; Howard A Fine; Susan M Chang; H Ian Robins; Karen Fink; Lisa De Angelis; Minesh Mehta; Emmanuelle di Tomaso; Jan Drappatz; Santosh kesari; Keith L Ligon; Ken Aldape; Rakesh K Jain; Charles D Stiles; Merrill J Egorin; Michael D Prados
Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).
Neuro-oncology 2009;11(6):853-60.
2009: Henry S Friedman; Michael D Prados; Patrick Y Wen; Tom Mikkelsen; David Schiff; Lauren E Abrey; W K Alfred Yung; Nina Paleologos; Martin K Nicholas; Randy Jensen; James J Vredenburgh; Jane Huang; Maoxia Zheng; Timothy F Cloughesy
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(28):4733-40.
2009: Morris D Groves; Kenneth R Hess; Vinay K Puduvalli; Howard Colman; Charles A Conrad; Mark R Gilbert; Jeffrey Weinberg; Massimo Cristofanilli; W K Alfred Yung; Ta-Jen Liu
Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma.
Journal of neuro-oncology 2009;94(2):229-34.
2009: Ta-Jen Liu; Dimpy Koul; Tiffany A Lafortune; Ningyi Tiao; Rui Jun Shen; Sauveur-Michel Maira; Carlos Garcia-Echevrria; W K Alfred Yung
NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas.
Molecular cancer therapeutics 2009;8(8):2204-10.
2009: W K Alfred Yung
Quality of life: a fertile field for inquiry.
Neuro-oncology 2009;11(3):241.
2009: Garth Powis; Nathan T Ihle; W K Alfred Yung
Inhibiting PI-3-K for glioma therapy.
Cell cycle (Georgetown, Tex.) 2009;8(3):335.
2008: Michael Weller; W K Alfred Yung
Bevacizumab--news from the fast lane?
Neuro-oncology 2008;10(5):647.
2008: John F de Groot; Mark R Gilbert; Kenneth Aldape; Kenneth R Hess; T A Hanna; Sandra Ictech; Morris D Groves; Charles Conrad; Howard Colman; Vinay K Puduvalli; Victor Levin; W K Alfred Yung
Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma.
Journal of neuro-oncology 2008;90(1):89-97.
2008: John F de Groot; W K Alfred Yung
Bevacizumab and irinotecan in the treatment of recurrent malignant gliomas.
Cancer journal (Sudbury, Mass.) 2008;14(5):279-85.
2008: Susan M Chang; Kathleen R Lamborn; John Kuhn; W K Alfred Yung; Mark R Gilbert; Patrick Y Wen; Howard A Fine; Minesh Mehta; Lisa De Angelis; Frank S Lieberman; Timothy F Cloughesy; H Ian Robins; Lauren E Abrey; Michael D Prados
Neurooncology clinical trial design for targeted therapies: lessons learned from the North American Brain Tumor Consortium.
Neuro-oncology 2008;10(4):631-42.
2008: John F de Groot; Yuji Piao; Li Lu; Gregory N Fuller; W K Alfred Yung
Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation.
Journal of neuro-oncology 2008;88(2):121-33.
2008: Benjamin W Corn; Jennifer Moughan; Jonathan Knisely; Sherry W Fox; Arnab Chakravarti; W K Alfred Yung; Walter Curran; H Ian Robins; David G Brachman; Randal H Henderson; Minesh Mehta; Benjamin Movsas
Prospective evaluation of quality of life and neurocognitive effects in patients with multiple brain metastases receiving whole-brain radiotherapy with or without thalidomide on Radiation Therapy Oncology Group (RTOG) trial 0118.
International journal of radiation oncology, biology, physics 2008;71(1):71-8.
2008: Kathleen R Lamborn; W K Alfred Yung; Susan M Chang; Patrick Y Wen; Timothy F Cloughesy; Lisa De Angelis; H Ian Robins; Frank S Lieberman; Howard A Fine; Karen L Fink; Larry Junck; Lauren E Abrey; Mark R Gilbert; Minesh Mehta; John Kuhn; Kenneth Aldape; Janelle Hibberts; Pamela M Peterson; Michael D Prados
Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas.
Neuro-oncology 2008;10(2):162-70.
2008: Morris D Groves; Michael J Glantz; Marc C Chamberlain; Karen E Baumgartner; Charles A Conrad; Sigmund Hsu; Jeffrey S Wefel; Mark R Gilbert; Sandra Ictech; Kathy U Hunter; Arthur Forman; Vinay K Puduvalli; Howard Colman; Kenneth R Hess; W K Alfred Yung
A multicenter phase II trial of intrathecal topotecan in patients with meningeal malignancies.
Neuro-oncology 2008;10(2):208-15.
2008: Vinay K Puduvalli; Pierre Giglio; Morris D Groves; Kenneth R Hess; Mark R Gilbert; Srikanth Mahankali; Edward F Jackson; Victor Levin; Charles A Conrad; Sigmund H Hsu; Howard Colman; John F de Groot; Melesa G Ritterhouse; Sandra E Ictech; W K Alfred Yung
Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme.
Neuro-oncology 2008;10(2):216-22.
2008: W K Alfred Yung
Carrying Neuro-Oncology to a world that needs knowledge.
Neuro-oncology 2008;10(1):1.
2008: Pablo Freire; Marco Vilela; Helena Deus; Yong-Wan Kim; Dimpy Koul; Howard Colman; Kenneth Aldape; Oliver Bogler; W K Alfred Yung; Kevin R Coombes; Gordon B Mills; Ana T Vasconcelos; Jonas Almeida
Exploratory analysis of the copy number alterations in glioblastoma multiforme.
PloS one 2008;3(12):e4076.
2007: Marta M Alonso; Candelaria Gomez-Manzano; B Nebiyou Bekele; W K Alfred Yung; Juan Fueyo
Adenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter.
Cancer research 2007;67(24):11499-504.
2007: Monica E Loghin; Michael D Prados; Patrick Y Wen; Larry Junck; Frank S Lieberman; Howard A Fine; Karen L Fink; Minesh Metha; John Kuhn; Kathleen R Lamborn; Susan M Chang; Timothy F Cloughesy; Lisa De Angelis; Ian H Robins; Kenneth Aldape; W K Alfred Yung
Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7133-8.
2007: Juinn-Lin Liu; Zhenyu Mao; Tiffany A Lafortune; Marta M Alonso; Gary E Gallick; Juan Fueyo; W K Alfred Yung
Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade.
Cancer research 2007;67(22):11054-63.
2007: Michael Scheurer; Carol J Etzel; Mei Liu; Randa A el-Zein; Gladstone Airewele; Beatrice Malmer; Kenneth Aldape; Jeffrey S Weinberg; W K Alfred Yung; Melissa L Bondy
Aggregation of cancer in first-degree relatives of patients with glioma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(11):2491-5.
2007: Rongcai Jiang; Woonyoung Choi; Asad Khan; Kenneth Hess; Eugene W Gerner; Robert A Casero; W K Alfred Yung; Stanley R Hamilton; Wei Zhang
Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma.
International journal of oncology 2007;31(2):431-40.
2007: Marta M Alonso; Candelaria Gomez-Manzano; Hong Jiang; Nebiyou Bekele; Yuji Piao; W K Alfred Yung; Ramon Alemany; Juan Fueyo
Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo.
Cancer gene therapy 2007;14(8):756-61.
2007: Christopher E Pelloski; Karla V Ballman; Alfred F Furth; LI Zhang; E Lin; Erik P Sulman; Krishna Bhat; J Matthew McDonald; W K Alfred Yung; Howard Colman; Shiao Y Woo; Amy B Heimberger; Dima Suki; Michael D Prados; Susan M Chang; Fred G Barker; Jan C Buckner; C David James; Kenneth Aldape
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(16):2288-94.
2007: Dimpy Koul; Ruijun Shen; Shishir Shishodia; Yasanuri Takada; Krishna P Bhat; Shrikanth A G Reddy; Bharat B Aggarwal; W K Alfred Yung
PTEN down regulates AP-1 and targets c-fos in human glioma cells via PI3-kinase/Akt pathway.
Molecular and cellular biochemistry 2007;300(1-2):77-87.
2007: Melissa V Olson; David G Johnson; Hong Jiang; Jing Xu; Marta M Alonso; Kenneth Aldape; Gregory N Fuller; B Nebiyou Bekele; W K Alfred Yung; Candelaria Gomez-Manzano; Juan Fueyo
Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.
Cancer research 2007;67(9):4005-9.
2007: Ta-Jen Liu; Tiffany A Lafortune; Toshiyuki Honda; Osamu Ohmori; Shinji Hatakeyama; Thomas Meyer; Dowdy Jackson; John de Groot; W K Alfred Yung
Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo.
Molecular cancer therapeutics 2007;6(4):1357-67.
2007: Dianren Xia; Harish Srinivas; Young-Ho Ahn; Gautam Sethi; Xiaoyang Sheng; W K Alfred Yung; Qianghua Xia; Paul J Chiao; Heetae Kim; Powel H Brown; Ignacio I Wistuba; Bharat B Aggarwal; Jonathan M Kurie
Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway.
The Journal of biological chemistry 2007;282(6):3507-19.
2007: Morris D Groves; Vinay K Puduvalli; Susan M Chang; Charles A Conrad; Mark R Gilbert; Ivo W Tremont-Lukats; Ta-Jen Liu; Pamela Peterson; David Schiff; Timothy F Cloughesy; Patrick Y Wen; Harry S Greenberg; Lauren E Abrey; Lisa De Angelis; Kenneth R Hess; Kathleen R Lamborn; Michael D Prados; W K Alfred Yung
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
Journal of neuro-oncology 2007;81(3):271-7.
2007: Yan Xia; Ji Wang; Ta-Jen Liu; W K Alfred Yung; Tony Hunter; Zhimin Lu
c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis.
Molecular cell 2007;25(2):219-32.
2007: W K Alfred Yung; C David James
Mapping the future of Neuro-Oncology.
Neuro-oncology 2007;9(1):1-2.
2006: Hong Jiang; Melissa V Olson; Diana R Medrano; Ok-Hee Lee; Jing Xu; Yuji Piao; Marta M Alonso; Candelaria Gomez-Manzano; Mien-Chie Hung; W K Alfred Yung; Juan Fueyo
A novel CRM1-dependent nuclear export signal in adenoviral E1A protein regulated by phosphorylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2603-5.
2006: Dimpy Koul; Yasunari Takada; Ruijun Shen; Bharat B Aggarwal; W K Alfred Yung
PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kappaB signaling pathway in human glioma cells.
Biochemical and biophysical research communications 2006;350(2):463-71.
2006: Howard Colman; Brian A Berkey; Moshe H Maor; Morris D Groves; Christopher J Schultz; Sandra Vermeulen; Diana F Nelson; Minesh Mehta; W K Alfred Yung
Phase II Radiation Therapy Oncology Group trial of conventional radiation therapy followed by treatment with recombinant interferon-beta for supratentorial glioblastoma: results of RTOG 9710.
International journal of radiation oncology, biology, physics 2006;66(3):818-24.
2006: Debra A Mayes; Yuanjie Hu; Yue Teng; Eric Siegel; Xiaosong Wu; Kishori Panda; Fang Tan; W K Alfred Yung; Yi-Hong Zhou
PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene.
Cancer research 2006;66(20):9809-17.
2006: Morris D Groves; Vinay K Puduvalli; Charles A Conrad; Mark R Gilbert; W K Alfred Yung; Kurt A Jaeckle; Vivien Liu; Kenneth R Hess; Kenneth Aldape; Victor Levin
Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status.
Journal of neuro-oncology 2006;80(1):83-90.
2006: Timothy F Cloughesy; Patrick Y Wen; H Ian Robins; Susan M Chang; Morris D Groves; Karen L Fink; Larry Junck; David Schiff; Lauren E Abrey; Mark R Gilbert; Frank S Lieberman; John Kuhn; Lisa De Angelis; Minesh Mehta; Jeffrey J Raizer; W K Alfred Yung; Kenneth Aldape; John Wright; Kathleen R Lamborn; Michael D Prados
Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(22):3651-6.
2006: Christopher E Pelloski; E Lin; LI Zhang; W K Alfred Yung; Howard Colman; Juinn-Lin Liu; Shiao Y Woo; Amy B Heimberger; Dima Suki; Michael Prados; Susan Chang; Fred G Barker; Gregory N Fuller; Kenneth Aldape
Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(13):3935-41.
2006: Victor Levin; Surasak Phuphanich; W K Alfred Yung; Peter A Forsyth; Rolando Del Maestro; James R Perry; Gregory N Fuller; Mark Baillet
Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation.
Journal of neuro-oncology 2006;78(3):295-302.
2006: Ok-Hee Lee; Juan Fueyo; Jing Xu; W K Alfred Yung; Michael G Lemoine; Frederick F Lang; B Nebiyou Bekele; Xian Zhou; Marta A Alonso; Kenneth Aldape; Gregory N Fuller; Candelaria Gomez-Manzano
Sustained angiopoietin-2 expression disrupts vessel formation and inhibits glioma growth.
Neoplasia (New York, N.Y.) 2006;8(5):419-28.
2006: Marta M Alonso; Juan Fueyo; W K Alfred Yung; Candelaria Gomez-Manzano
E2F1 and telomerase: alliance in the dark side.
Cell cycle (Georgetown, Tex.) 2006;5(9):930-5.
2006: Victor Levin; Pierre Giglio; Vinay K Puduvalli; Jacob L Jochec; Morris D Groves; W K Alfred Yung; K Hess
Combination chemotherapy with 13-cis-retinoic acid and celecoxib in the treatment of glioblastoma multiforme.
Journal of neuro-oncology 2006;78(1):85-90.
2006: Michael D Prados; Kathleen R Lamborn; W K Alfred Yung; Kurt A Jaeckle; H Ian Robins; Minesh Mehta; Howard A Fine; Patrick Y Wen; Timothy F Cloughesy; Susan Chang; M Kelly Nicholas; David Schiff; Harry S Greenberg; Larry Junck; Karen Fink; Kenneth Hess; John Kuhn
A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.
Neuro-oncology 2006;8(2):189-93.
2006: Dimpy Koul; Ruijun Shen; Sherry Bergh; Xiaoyang Sheng; Shishir Shishodia; Tiffany A Lafortune; Yiling Lu; John F de Groot; Gordon B Mills; W K Alfred Yung
Inhibition of Akt survival pathway by a small-molecule inhibitor in human glioblastoma.
Molecular cancer therapeutics 2006;5(3):637-44.
2006: Candelaria Gomez-Manzano; Marta M Alonso; W K Alfred Yung; Frank McCormick; David T Curiel; Frederick F Lang; Hong Jiang; B Nebiyou Bekele; Xian Zhou; Ramon Alemany; Juan Fueyo
Delta-24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):556-62.
2005: Marta M Alonso; Juan Fueyo; Jerry W Shay; Kenneth Aldape; Hong Jiang; Ok-Hee Lee; David G Johnson; Jing Xu; Yasuko Kondo; Takao Kanzawa; Satoru Kyo; B Nebiyou Bekele; Xian Zhou; Janice Nigro; J Matthew McDonald; W K Alfred Yung; Candelaria Gomez-Manzano
Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.
Journal of the National Cancer Institute 2005;97(21):1589-600.
2005: Dimpy Koul; Ruijun Shen; Sherry Bergh; Yiling Lu; John F de Groot; Ta-Jen Liu; Gordon B Mills; W K Alfred Yung
Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma.
Molecular cancer therapeutics 2005;4(11):1681-8.
2005: Yi-Hong Zhou; Kenneth R Hess; Longjian Liu; Mark E Linskey; W K Alfred Yung
Modeling prognosis for patients with malignant astrocytic gliomas: quantifying the expression of multiple genetic markers and clinical variables.
Neuro-oncology 2005;7(4):485-94.
2005: Hong Jiang; Ramon Alemany; Candelaria Gomez-Manzano; Diana R Medrano; Michael G Lemoine; Melissa V Olson; Marta M Alonso; Ok-Hee Lee; Charles C Conrad; W K Alfred Yung; Juan Fueyo
Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses.
Neoplasia (New York, N.Y.) 2005;7(8):723-9.
2005: Juinn-Lin Liu; Xiaoyang Sheng; Zsuzsanna K Hortobagyi; Zhenyu Mao; Gary E Gallick; W K Alfred Yung
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
Molecular and cellular biology 2005;25(14):6211-24.
2005: John F de Groot; Ta-Jen Liu; Gregory Fuller; W K Alfred Yung
The excitatory amino acid transporter-2 induces apoptosis and decreases glioma growth in vitro and in vivo.
Cancer research 2005;65(5):1934-40.
2005: Janice M Nigro; Anjan Misra; LI Zhang; Ivan Smirnov; Howard Colman; Chandi Griffin; Natalie Ozburn; Mingang Chen; Edward Pan; Dimpy Koul; W K Alfred Yung; Burt Feuerstein; Kenneth Aldape
Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma.
Cancer research 2005;65(5):1678-86.
2005: Charles Conrad; Ryan Miller; Yongjie Ji; Candelaria Gomez-Manzano; Suman Bharara; John S McMurray; Frederick F Lang; Franklin Wong; Raymond Sawaya; W K Alfred Yung; Juan Fueyo
Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization.
Cancer gene therapy 2005;12(3):284-94.
2005: Yi-Hong Zhou; Xiaosong Wu; Fang Tan; Yue-Xi Shi; Tricia Glass; T J Liu; Kyle Wathen; Kenneth R Hess; Joy Gumin; Frederick Lang; W K Alfred Yung
PAX6 suppresses growth of human glioblastoma cells.
Journal of neuro-oncology 2005;71(3):223-9.
2005: Hong Jiang; Candelaria Gomez-Manzano; Ramon Alemany; Diana R Medrano; Marta Alonso; B Nebiyou Bekele; E Lin; Charles C Conrad; W K Alfred Yung; Juan Fueyo
Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas.
Neoplasia (New York, N.Y.) 2005;7(1):48-56.
2004: Vinay K Puduvalli; W K Alfred Yung; Kenneth R Hess; John Kuhn; Morris D Groves; Victor Levin; James Zwiebel; Susan M Chang; Timothy F Cloughesy; Larry Junck; Patrick Y Wen; Frank S Lieberman; Charles A Conrad; Mark R Gilbert; Christina A Meyers; Vivien Liu; Minesh Mehta; M Kelly Nicholas; Michael Prados
Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(21):4282-9.
2004: W K Alfred Yung
Current therapies for glioblastoma.
Clinical advances in hematology & oncology : H&O 2004;2(9):572-3.
2004: Li-E Wang; Melissa L Bondy; Hongbing Shen; Randa A el-Zein; Kenneth Aldape; Yumei Cao; Vinay Pudavalli; Victor Levin; W K Alfred Yung; Qingyi Wei
Polymorphisms of DNA repair genes and risk of glioma.
Cancer research 2004;64(16):5560-3.
2004: Candelaria Gomez-Manzano; W K Alfred Yung; Ramon Alemany; Juan Fueyo
Genetically modified adenoviruses against gliomas: from bench to bedside.
Neurology 2004;63(3):418-26.
2004: Siew-Ju See; Victor Levin; W K Alfred Yung; Kenneth R Hess; Morris D Groves
13-cis-retinoic acid in the treatment of recurrent glioblastoma multiforme.
Neuro-oncology 2004;6(3):253-8.
2004: Susan M Chang; Michael D Prados; W K Alfred Yung; Howard A Fine; Larry Junck; Harry S Greenberg; H Ian Robins; Minesh Mehta; Karen L Fink; Kurt A Jaeckle; John Kuhn; Kenneth Hess; Clifford Schold
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
Cancer 2004;100(8):1712-6.
2004: Candelaria Gomez-Manzano; Cristina Balague; Ramon Alemany; Michael G Lemoine; Paraskevi G Mitlianga; Hong Jiang; Asadullah Khan; Marta Alonso; Frederick F Lang; Charles A Conrad; Ta-Jen Liu; B Nebiyou Bekele; W K Alfred Yung; Juan Fueyo
A novel E1A-E1B mutant adenovirus induces glioma regression in vivo.
Oncogene 2004;23(10):1821-8.
2004: Julie A Cerrato; Tahira Khan; Dimpy Koul; Frederick F Lang; Charles A Conrad; W K Alfred Yung; Ta-Jen Liu
Differential activation of the Fas/CD95 pathway by Ad-p53 in human gliomas.
International journal of oncology 2004;24(2):409-17.
2004: Michael D Prados; W K Alfred Yung; Kurt A Jaeckle; H Ian Robins; Minesh Mehta; Howard A Fine; Patrick Y Wen; Timothy F Cloughesy; Susan M Chang; M Kelly Nicholas; David Schiff; Harry S Greenberg; Larry Junck; Karen L Fink; Kenneth R Hess; John Kuhn
Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.
Neuro-oncology 2004;6(1):44-54.
2004: Michael D Prados; W K Alfred Yung; Howard A Fine; Harry S Greenberg; Larry Junck; Susan M Chang; M Kelly Nicholas; H Ian Robins; Minesh Mehta; Karen L Fink; Kurt A Jaeckle; John Kuhn; Kenneth R Hess; S Clifford Schold
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
Neuro-oncology 2004;6(1):33-7.
2003: Yiling Lu; Qinghua Yu; Jue Hui Liu; Jinyi Zhang; Hongwei Wang; Dimpy Koul; John S McMurray; Xianjun Fang; W K Alfred Yung; Katherine A Siminovitch; Gordon B Mills
Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.
The Journal of biological chemistry 2003;278(41):40057-66.
2003: Bouthaina S Dabaja; Peter McLaughlin; Chul Ha; Barbara Pro; Christina A Meyers; Lee F Seabrooke; Richard B Wilder; Athanassios P Kyritsis; H Alejandro Preti; W K Alfred Yung; Victor Levin; Fernando Cabanillas; James D Cox
Primary central nervous system lymphoma: Phase I evaluation of infusional bromodeoxyuridine with whole brain accelerated fractionation radiation therapy after chemotherapy.
Cancer 2003;98(5):1021-8.
2003: Yi-Hong Zhou; Fang Tan; Kenneth R Hess; W K Alfred Yung
The expression of PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: relationship to tumor grade and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3369-75.
2003: Frederick F Lang; Janet M Bruner; Gregory N Fuller; Kenneth Aldape; Michael D Prados; Susan Chang; Mitchel S Berger; Michael W McDermott; Sandeep Kunwar; Larry Junck; William F Chandler; James Zwiebel; Richard S. Kaplan; W K Alfred Yung
Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(13):2508-18.
2003: Kurt A Jaeckle; Kenneth R Hess; W K Alfred Yung; Harry S Greenberg; Howard A Fine; David Schiff; Ian F Pollack; John Kuhn; Karen Fink; Minesh Mehta; Timothy F Cloughesy; M Kelly Nicholas; Susan Chang; Michael Prados
Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(12):2305-11.
2003: Juan Fueyo; Ramon Alemany; Candelaria Gomez-Manzano; Gregory N Fuller; Asadullah Khan; Charles A Conrad; Ta-Jen Liu; Hong Jiang; Michael G Lemoine; Kaori Suzuki; Raymond Sawaya; David T Curiel; W K Alfred Yung; Frederick F Lang
Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway.
Journal of the National Cancer Institute 2003;95(9):652-60.
2003: Victor Levin; Kenneth R Hess; Ali Choucair; Patrick J Flynn; Kurt A Jaeckle; Athanassios P Kyritsis; W K Alfred Yung; Michael D Prados; Janet M Bruner; Sandra Ictech; Mary Jo Gleason; Hyung Woo Kim
Phase III randomized study of postradiotherapy chemotherapy with combination alpha-difluoromethylornithine-PCV versus PCV for anaplastic gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):981-90.
2003: Vinay K Puduvalli; Masood Hashmi; Leslie D McAllister; Victor Levin; Kenneth R Hess; Michael Prados; Kurt A Jaeckle; W K Alfred Yung; Saundra S Buys; Janet M Bruner; Jeannette J Townsend; Richard Davis; Raymond Sawaya; Athanassios P Kyritsis
Anaplastic oligodendrogliomas: prognostic factors for tumor recurrence and survival.
Oncology 2003;65(3):259-66.
2003: Candelaria Gomez-Manzano; Juan Fueyo; Hong Jiang; Tricia L Glass; Ho-Young Lee; Min Hu; Juinn-Lin Liu; Sushma L Jasti; Ta-Jen Liu; Charles A Conrad; W K Alfred Yung
Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis.
Annals of neurology 2003;53(1):109-17.
2002: Yi-Hong Zhou; Jessica B Zheng; Xun Gu; Grady F Saunders; W K Alfred Yung
Novel PAX6 binding sites in the human genome and the role of repetitive elements in the evolution of gene regulation.
Genome research 2002;12(11):1716-22.
2002: Frederick F Lang; Mark R Gilbert; Vinay K Puduvalli; Jeffrey Weinberg; Victor Levin; W K Alfred Yung; Raymond Sawaya; Gregory N Fuller; Charles A Conrad
Toward better early-phase brain tumor clinical trials: a reappraisal of current methods and proposals for future strategies.
Neuro-oncology 2002;4(4):268-77.
2002: Dimpy Koul; Ruijun Shen; Anil Garyali; Li Dao Ke; Ta-Jen Liu; W K Alfred Yung
MMAC/PTEN tumor suppressor gene regulates vascular endothelial growth factor-mediated angiogenesis in prostate cancer.
International journal of oncology 2002;21(3):469-75.
2002: Victor Levin; W K Alfred Yung; Janet Bruner; Athanassios P Kyritsis; Norman E Leeds; Mary Jo Gleason; Kenneth R Hess; Christina A Meyers; Sandra Ictech; E Chang; Moshe H Maor
Phase II study of accelerated fractionation radiation therapy with carboplatin followed by PCV chemotherapy for the treatment of anaplastic gliomas.
International journal of radiation oncology, biology, physics 2002;53(1):58-66.
2002: Dimpy Koul; Samar A Jasser; Yiling Lu; Michael A Davies; Ruijun Shen; Yuexi Shi; Gordon B Mills; W K Alfred Yung
Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.
Oncogene 2002;21(15):2357-64.
2002: H Ian Robins; Susan M Chang; Michael D Prados; W K Alfred Yung; Kenneth Hess; David Schiff; Harry S Greenberg; Karen Fink; Kelly Nicolas; John Kuhn; Timothy F Cloughesy; Larry Junck; Minesh Mehta
A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study.
Neuro-oncology 2002;4(2):109-14.
2002: Xiaoyang Sheng; Dimpy Koul; Juinn-Lin Liu; Ta-Jen Liu; W K Alfred Yung
Promoter analysis of tumor suppressor gene PTEN: identification of minimum promoter region.
Biochemical and biophysical research communications 2002;292(2):422-6.
2002: Li Dao Ke; Yue-Xi Shi; W K Alfred Yung
VEGF(121), VEGF(165) overexpression enhances tumorigenicity in U251 MG but not in NG-1 glioma cells.
Cancer research 2002;62(6):1854-61.
2002: Morris D Groves; Vinay K Puduvalli; Kenneth R Hess; Kurt A Jaeckle; Pamela Peterson; W K Alfred Yung; Victor Levin
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(5):1383-8.
2002: Lara J Kunschner; Howard A Fine; Kenneth Hess; Kurt A Jaeckle; Athanassios P Kyritsis; W K Alfred Yung
CI-980 for the treatment of recurrent or progressive malignant gliomas: national central nervous system consortium phase I-II evaluation of CI-980.
Cancer investigation 2002;20(7-8):948-54.
2002: Gregory N Fuller; Kenneth R Hess; Chang Hun Rhee; W K Alfred Yung; Raymond A Sawaya; Janet M Bruner; Wei Zhang
Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene expression profiles parallels morphology-based classification, correlates with survival, and reveals clinically-relevant novel glioma subsets.
Brain pathology (Zurich, Switzerland) 2002;12(1):108-16.
2001: Dimpy Koul; R Parthasarathy; Ruijun Shen; Michael A Davies; Samar A Jasser; Chintala Shravan; Jasti Sambasiva Rao; Yi Sun; E N Benvenisite; Ta-Jen Liu; W K Alfred Yung
Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.
Oncogene 2001;20(46):6669-78.
2001: Candelaria Gomez-Manzano; Paraskevi G Mitlianga; Juan Fueyo; Ho-Young Lee; Min Hu; Kevin B Spurgers; Tricia L Glass; Dimpy Koul; Ta-Jen Liu; Timothy J McDonnell; W K Alfred Yung
Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2.
Cancer research 2001;61(18):6693-7.
2001: W K Alfred Yung
Future directions for temozolomide therapy.
Seminars in oncology 2001;28(4 Suppl 13):43-6.
2001: Sanjeeva Mohanam; Sushma L Jasti; Shakuntala Kondraganti; Nirmala Chandrasekar; Yoshiaki Kin; Gregory N Fuller; Seeta Sajani Lakka; Athanassios P Kyritsis; Dzung Hong Dinh; Charles William Olivero; Meena Gujrati; W K Alfred Yung; Jasti Sambasiva Rao
Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2519-26.
2001: Lara J Kunschner; John Frank Kuttesch; Kenneth Hess; W K Alfred Yung
Survival and recurrence factors in adult medulloblastoma: the M.D. Anderson Cancer Center experience from 1978 to 1998.
Neuro-oncology 2001;3(3):167-73.
2001: Dimpy Koul; Yixin Yao; James L Abbruzzese; W K Alfred Yung; Shrikanth A G Reddy
Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway.
The Journal of biological chemistry 2001;276(14):11402-8.
2001: Seeta Sajani Lakka; R Rajagopal; M K Rajan; Pamarthi M Mohan; Yoshiaki Adachi; Dzung Hong Dinh; Charles William Olivero; Meena Gujrati; Francis Ali-Osman; Jack A Roth; W K Alfred Yung; Athanassios P Kyritsis; Jasti Sambasiva Rao
Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(4):1087-93.
2001: J A Cerrato; W K Alfred Yung; Ta-Jen Liu
Introduction of mutant p53 into a wild-type p53-expressing glioma cell line confers sensitivity to Ad-p53-induced apoptosis.
Neuro-oncology 2001;3(2):113-22.
2001: Juan Fueyo; Candelaria Gomez-Manzano; Ta-Jen Liu; W K Alfred Yung
Delivery of cell cycle genes to block astrocytoma growth.
Journal of neuro-oncology 2001;51(3):277-87.
2001: Paraskevi G Mitlianga; Athanassios P Kyritsis; Candelaria Gomez-Manzano; Michael G Lemoine; Min Hu; Ta-Jen Liu; W K Alfred Yung; Juan Fueyo
Co-expression of E2F-2 enhances the p53 anti-cancer effect in human glioma cells.
International journal of oncology 2001;18(2):343-7.
2000: W K Alfred Yung; Robert Albright; J Olson; R Fredericks; K Fink; Michael D Prados; M Brada; A Spence; R J Hohl; W Shapiro; Michael Glantz; Harry S Greenberg; R G Selker; N A Vick; Roy Rampling; H Friedman; P Phillips; Janet Bruner; N Yue; David Osoba; Sara Zaknoen; Victor Levin
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse.
British journal of cancer 2000;83(5):588-93.
2000: Tricia L Glass; Ta-Jen Liu; W K Alfred Yung
Inhibition of cell growth in human glioblastoma cell lines by farnesyltransferase inhibitor SCH66336.
Neuro-oncology 2000;2(3):151-8.
2000: Li Dao Ke; Yue-Xi Shi; Seock-Ah Im; X Chen; W K Alfred Yung
The relevance of cell proliferation, vascular endothelial growth factor, and basic fibroblast growth factor production to angiogenesis and tumorigenicity in human glioma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(6):2562-72.
2000: W K Alfred Yung
Temozolomide in malignant gliomas.
Seminars in oncology 2000;27(3 Suppl 6):27-34.
2000: L D Ke; Z Chen; W K Alfred Yung
A reliability test of standard-based quantitative PCR: exogenous vs endogenous standards.
Molecular and cellular probes 2000;14(2):127-35.
2000: Christina A Meyers; Kenneth R Hess; W K Alfred Yung; Victor Levin
Cognitive function as a predictor of survival in patients with recurrent malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(3):646-50.
2000: Juan Fueyo; Candelaria Gomez-Manzano; Ramon Alemany; P S Lee; Timothy J McDonnell; Paraskevi G Mitlianga; Yue-Xi Shi; Victor Levin; W K Alfred Yung; Athanassios P Kyritsis
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.
Oncogene 2000;19(1):2-12.
2000: Seeta Sajani Lakka; Sushma L Jasti; Athanassios P Kyritsis; W K Alfred Yung; Francis Ali-Osman; Garth L Nicolson; Jasti Sambasiva Rao
Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades.
Clinical & experimental metastasis 2000;18(3):245-52.
1999: Chintala Shravan; Athanassios P Kyritsis; Pamarthi M Mohan; Sanjeeva Mohanam; Raymond Sawaya; Z Gokslan; W K Alfred Yung; PA Steck; Joon H Uhm; Bharat B Aggarwal; Jasti Sambasiva Rao
Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.
Molecular carcinogenesis 1999;26(4):274-85.
1999: Frederick F Lang; W K Alfred Yung; Raymond Sawaya; P J Tofilon
Adenovirus-mediated p53 gene therapy for human gliomas.
Neurosurgery 1999;45(5):1093-104.
1999: Ramon Alemany; Candelaria Gomez-Manzano; Cristina Balagué; W K Alfred Yung; David T Curiel; Athanassios P Kyritsis; Juan Fueyo
Gene therapy for gliomas: molecular targets, adenoviral vectors, and oncolytic adenoviruses.
Experimental cell research 1999;252(1):1-12.
1999: Kenneth R Hess; ET Wong; Kurt A Jaeckle; Athanassios P Kyritsis; Victor Levin; Michael D Prados; W K Alfred Yung
Response and progression in recurrent malignant glioma.
Neuro-oncology 1999;1(4):282-8.
1999: W K Alfred Yung; Michael D Prados; R Yaya-Tur; S S Rosenfeld; M Brada; Henry S Friedman; Robert Albright; John Olson; Susan M Chang; A M O'Neill; Allan H Friedman; Janet Bruner; N Yue; Margaret Dugan; Sara Zaknoen; Victor Levin
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(9):2762-71.
1999: Gregory N Fuller; Chang Hun Rhee; Kenneth R Hess; L S Caskey; R Wang; Janet M Bruner; W K Alfred Yung; Weiqing Zhang
Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling.
Cancer research 1999;59(17):4228-32.
1999: ET Wong; Kenneth R Hess; Mary Jo Gleason; Kurt A Jaeckle; Athanassios P Kyritsis; Michael D Prados; Victor Levin; W K Alfred Yung
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(8):2572-8.
1999: Morris D Groves; Moshe H Maor; C Meyers; Athanassios P Kyritsis; Kurt A Jaeckle; W K Alfred Yung; Raymond Sawaya; K Hess; Janet M Bruner; Pamela Peterson; Victor Levin
A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme.
International journal of radiation oncology, biology, physics 1999;45(1):127-35.
1999: P Tang; Samar A Jasser; J C Sung; Y Shi; PA Steck; W K Alfred Yung
Transforming growth factor-alpha antisense vectors can inhibit glioma cell growth.
Journal of neuro-oncology 1999;43(2):127-35.
1999: Michael A Davies; Dimpy Koul; H Dhesi; R Berman; Timothy J McDonnell; David J McConkey; W K Alfred Yung; PA Steck
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN.
Cancer research 1999;59(11):2551-6.
1999: T Sano; Hui Lin; X Chen; Lauren Langford; Dimpy Koul; Melissa L Bondy; Kenneth R Hess; Jeffrey N Myers; Y K Hong; W K Alfred Yung; PA Steck
Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis.
Cancer research 1999;59(8):1820-4.
1999: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung; Athanassios P Kyritsis
Targeting in gene therapy for gliomas.
Archives of neurology 1999;56(4):445-8.
1999: Seock-Ah Im; Candelaria Gomez-Manzano; Juan Fueyo; Ta-Jen Liu; Li Dao Ke; Jang-Seong Kim; Ho-Young Lee; PA Steck; Athanassios P Kyritsis; W K Alfred Yung
Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo.
Cancer research 1999;59(4):895-900.
1999: PA Steck; Hui Lin; Lauren Langford; Samar A Jasser; Dimpy Koul; W K Alfred Yung; MA Pershouse
Functional and molecular analyses of 10q deletions in human gliomas.
Genes, chromosomes & cancer 1999;24(2):135-43.
1999: Candelaria Gomez-Manzano; Juan Fueyo; F Alameda; Athanassios P Kyritsis; W K Alfred Yung
Gene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis.
International journal of molecular medicine 1999;3(1):81-5.
1998: Alice J Sigurdson; Melissa L Bondy; Kenneth R Hess; Steven Toms; Athanassios P Kyritsis; Jian Gu; Li-E Wang; Xuemei Wang; Phyllis Adatto; J L Bruner; W K Alfred Yung; Victor Levin; Qingyi Wei
Gamma-ray mutagen sensitivity and survival in patients with glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(12):3031-5.
1998: Michael A Davies; Ying Lu; T Sano; Xiang Fang; P Tang; Ruth Lapushin; Dimpy Koul; Robert Bookstein; David Stokoe; W K Alfred Yung; Gordon B Mills; PA Steck
Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.
Cancer research 1998;58(23):5285-90.
1998: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung; Athanassios P Kyritsis
The functional role of tumor suppressor genes in gliomas: clues for future therapeutic strategies.
Neurology 1998;51(5):1250-5.
1998: Hui Lin; Melissa L Bondy; Lauren Langford; Kenneth R Hess; George L Delclos; Xifeng Wu; W Chan; MA Pershouse; W K Alfred Yung; PA Steck
Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2447-54.
1998: Frederick F Lang; W K Alfred Yung; Uma Raju; F Libunao; N H Terry; Philip J Tofilon
Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene.
Journal of neurosurgery 1998;89(1):125-32.
1998: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung; Ta-Jen Liu; Ramon Alemany; Timothy J McDonnell; X Shi; Jasti Sambasiva Rao; Victor Levin; Athanassios P Kyritsis
Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo.
Nature medicine 1998;4(6):685-90.
1998: Li Dao Ke; Juan Fueyo; X Chen; PA Steck; Yue-Xi Shi; Seock-Ah Im; W K Alfred Yung
A novel approach to glioma gene therapy: down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes.
International journal of oncology 1998;12(6):1391-6.
1998: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung; Ta-Jen Liu; Ramon Alemany; Janet M Bruner; Chintala Shravan; Jasti Sambasiva Rao; Victor Levin; Athanassios P Kyritsis
Suppression of human glioma growth by adenovirus-mediated Rb gene transfer.
Neurology 1998;50(5):1307-15.
1998: AH Ligon; MA Pershouse; Samar A Jasser; Y K Hong; W K Alfred Yung; PA Steck
Differentially expressed gene products in glioblastoma cells suppressed for tumorigenicity.
Journal of neurovirology 1998;4(2):217-26.
1998: Kenneth R Hess; ET Wong; W K Alfred Yung
Assessing response to chemotherapy in malignant glioma: the role of steroids.
Neurology 1998;50(4):1197; disscussion 1197-8.
1998: ET Wong; Edward F Jackson; Kenneth R Hess; Donald F Schomer; John D Hazle; Athanassios P Kyritsis; Kurt A Jaeckle; W K Alfred Yung; Victor Levin; Norman E Leeds
Correlation between dynamic MRI and outcome in patients with malignant gliomas.
Neurology 1998;50(3):777-81.
1998: Juan Fueyo; Candelaria Gomez-Manzano; Vinay K Puduvalli; P Martin-Duque; Roman Perez-Soler; Victor Levin; W K Alfred Yung; Athanassios P Kyritsis
Adenovirus-mediated p16 transfer to glioma cells induces G1 arrest and protects from paclitaxel and topotecan: implications for therapy.
International journal of oncology 1998;12(3):665-9.
1997: P Tang; PA Steck; W K Alfred Yung
The autocrine loop of TGF-alpha/EGFR and brain tumors.
Journal of neuro-oncology 1997;35(3):303-14.
1997: David Teng; R Hu; Hui Lin; T Davis; D Iliev; Cynthia Frye; B Swedlund; K L Hansen; V L Vinson; Kathi L Gumpper; L Ellis; Adel El-Naggar; M Frazier; Samar A Jasser; Lauren Langford; J Lee; Gordon B Mills; MA Pershouse; R E Pollack; Carmen Tornos; P Troncoso; W K Alfred Yung; GH Fujii; AE Berson; PA Steck
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.
Cancer research 1997;57(23):5221-5.
1997: MA Pershouse; AH Ligon; Olivia M Pereira-Smith; Ann McNeill Killary; W K Alfred Yung; PA Steck
Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells.
Genes, chromosomes & cancer 1997;20(3):260-7.
1997: Chintala Shravan; Juan Fueyo; Candelaria Gomez-Manzano; B Venkaiah; R Bjerkvig; W K Alfred Yung; Raymond Sawaya; Athanassios P Kyritsis; Jasti Sambasiva Rao
Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro.
Oncogene 1997;15(17):2049-57.
1997: SE Kaba; Athanassios P Kyritsis; C Conrad; Mary Jo Gleason; R Newman; Victor Levin; W K Alfred Yung
The treatment of recurrent cerebral gliomas with all-trans-retinoic acid (tretinoin).
Journal of neuro-oncology 1997;34(2):145-51.
1997: Candelaria Gomez-Manzano; Juan Fueyo; Athanassios P Kyritsis; Timothy J McDonnell; PA Steck; Victor Levin; W K Alfred Yung
Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.
Journal of the National Cancer Institute 1997;89(14):1036-44.
1997: Qingyi Wei; Melissa L Bondy; Li Mao; Y Gaun; Lie Cheng; Joan E. Cunningham; Y Fan; Janet M Bruner; W K Alfred Yung; Victor Levin; Athanassios P Kyritsis
Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas.
Cancer research 1997;57(9):1673-7.
1997: PA Steck; MA Pershouse; Samar A Jasser; W K Alfred Yung; Hui Lin; AH Ligon; Lauren Langford; ML Baumgard; T Hattier; T Davis; Cynthia Frye; R Hu; B Swedlund; David Teng; Sean V Tavtigian
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.
Nature genetics 1997;15(4):356-62.
1997: AH Ligon; MA Pershouse; Samar A Jasser; W K Alfred Yung; PA Steck
Identification of a novel gene product, RIG, that is down-regulated in human glioblastoma.
Oncogene 1997;14(9):1075-81.
1997: SE Kaba; Athanassios P Kyritsis; K Hess; W K Alfred Yung; R Mercier; Shaker R Dakhil; Kurt A Jaeckle; Victor Levin
TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(3):1063-70.
1997: SE Kaba; Franco DeMonte; Janet M Bruner; Athanassios P Kyritsis; Kurt A Jaeckle; Victor Levin; W K Alfred Yung
The treatment of recurrent unresectable and malignant meningiomas with interferon alpha-2B.
Neurosurgery 1997;40(2):271-5.
1997: MA Pershouse; Adel K El-Naggar; K Hurr; Hui Lin; W K Alfred Yung; PA Steck
Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma.
Oncogene 1997;14(3):369-73.
1996: W K Alfred Yung; Athanassios P Kyritsis; M J Gleason; Victor Levin
Treatment of recurrent malignant gliomas with high-dose 13-cis-retinoic acid.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(12):1931-5.
1996: Athanassios P Kyritsis; W K Alfred Yung; Kurt A Jaeckle; Janet Bruner; M J Gleason; S E Ictech; A Flowers; Victor Levin
Combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas.
Neurosurgery 1996;39(5):921-6.
1996: Juan Fueyo; Candelaria Gomez-Manzano; Janet M Bruner; Y Saito; B Zhang; W Zhang; Victor Levin; W K Alfred Yung; Athanassios P Kyritsis
Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas.
Oncogene 1996;13(8):1615-9.
1996: SE Kaba; Lauren Langford; W K Alfred Yung; Athanassios P Kyritsis
Resolution of recurrent malignant ganglioglioma after treatment with cis-retinoic acid.
Journal of neuro-oncology 1996;30(1):55-60.
1996: Candelaria Gomez-Manzano; Juan Fueyo; Athanassios P Kyritsis; PA Steck; Jack A Roth; Timothy J McDonnell; KD Steck; Victor Levin; W K Alfred Yung
Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis.
Cancer research 1996;56(4):694-9.
1996: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung; Gary L Clayman; Ta-Jen Liu; Janet Bruner; Victor Levin; Athanassios P Kyritsis
Adenovirus-mediated p16/CDKN2 gene transfer induces growth arrest and modifies the transformed phenotype of glioma cells.
Oncogene 1996;12(1):103-10.
1995: Athanassios P Kyritsis; Melissa L Bondy; Kenneth R Hess; Joan E. Cunningham; D Zhu; C J Amos; W K Alfred Yung; Victor Levin; J M Bruner
Prognostic significance of p53 immunoreactivity in patients with glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1617-22.
1995: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung; W Zhang; P S Lee; S Majumder; M Perhouse; Victor Levin; Athanassios P Kyritsis
A frequent polymorphism in exon 1 of the p16/CDKN2 gene.
Molecular and cellular probes 1995;9(6):465-6.
1995: Victor Levin; Moshe H Maor; Peter F Thall; W K Alfred Yung; Janet Bruner; Raymond Sawaya; Athanassios P Kyritsis; Norman E Leeds; S Woo; L Rodriguez
Phase II study of accelerated fractionation radiation therapy with carboplatin followed by vincristine chemotherapy for the treatment of glioblastoma multiforme.
International journal of radiation oncology, biology, physics 1995;33(2):357-64.
1995: P Van Tassel; Janet M Bruner; M H Maor; N E Leeds; M J Gleason; W K Alfred Yung; Victor Levin
MR of toxic effects of accelerated fractionation radiation therapy and carboplatin chemotherapy for malignant gliomas.
AJNR. American journal of neuroradiology 1995;16(4):715-26.
1995: PA Steck; AH Ligon; P Cheong; W K Alfred Yung; MA Pershouse
Two tumor suppressive loci on chromosome 10 involved in human glioblastomas.
Genes, chromosomes & cancer 1995;12(4):255-61.
1993: MA Pershouse; E Stubblefield; A Hadi; Ann McNeill Killary; W K Alfred Yung; PA Steck
Analysis of the functional role of chromosome 10 loss in human glioblastomas.
Cancer research 1993;53(20):5043-50.
1993: Athanassios P Kyritsis; W K Alfred Yung; Janet Bruner; M J Gleason; Victor Levin
The treatment of anaplastic oligodendrogliomas and mixed gliomas.
Neurosurgery 1993;32(3):365-70; discussion 371.
1993: C A Meyers; W K Alfred Yung
Delayed neurotoxicity of intraventricular interleukin-2: a case report.
Journal of neuro-oncology 1993;15(3):265-7.
1992: Victor Levin; Michael D Prados; W K Alfred Yung; M J Gleason; S Ictech; Mary Malec
Treatment of recurrent gliomas with eflornithine.
Journal of the National Cancer Institute 1992;84(18):1432-7.
1992: W K Alfred Yung; T J Janus; Moshe H Maor; Lynn Feun
Adjuvant chemotherapy with carmustine and cisplatin for patients with malignant gliomas.
Journal of neuro-oncology 1992;12(2):131-5.
1991: W K Alfred Yung; M Prados; Victor Levin; M R Fetell; J Bennett; M S Mahaley; Michael Salcman; E Etcubanas
Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: a phase I/II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(11):1945-9.
1991: W K Alfred Yung; L Mechtler; M J Gleason
Intravenous carboplatin for recurrent malignant glioma: a phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(5):860-4.
1991: Adam S Garden; Moshe H Maor; W K Alfred Yung; Janet M Bruner; Shiao Y Woo; R P Moser; Y Y Lee
Outcome and patterns of failure following limited-volume irradiation for malignant astrocytomas.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1991;20(2):99-110.
1990: L K Newton; W K Alfred Yung; L C Pettigrew; P A Steck
Growth regulatory activities of endothelial extracellular matrix: mediation by transforming growth factor-beta.
Experimental cell research 1990;190(1):127-32.
1990: W K Alfred Yung; A M Castellanos; P Van Tassel; R P Moser; S G Marcus
A pilot study of recombinant interferon beta (IFN-beta ser) in patients with recurrent glioma.
Journal of neuro-oncology 1990;9(1):29-34.
1989: Bernard L Maria; PA Steck; W K Alfred Yung; A Milici; Janet M Bruner; Sen Pathak; F F Becker
The modulation of astrocytic differentiation in cells derived from a medulloblastoma surgical specimen.
Journal of neuro-oncology 1989;7(4):329-38.
1989: W K Alfred Yung; M I Harris; Janet M Bruner; Lynn Feun
Intravenous BCNU and AZQ in patients with recurrent malignant gliomas.
Journal of neuro-oncology 1989;7(3):237-40.
1989: PA Steck; R P Moser; Janet M Bruner; L Liang; A N Freidman; Te-Long Hwang; W K Alfred Yung
Altered expression and distribution of heparan sulfate proteoglycans in human gliomas.
Cancer research 1989;49(8):2096-103.
1989: W K Alfred Yung; Reuben Lotan; P Lee; Dafna Lotan; PA Steck
Modulation of growth and epidermal growth factor receptor activity by retinoic acid in human glioma cells.
Cancer research 1989;49(4):1014-9.
1989: W K Alfred Yung
In vitro chemosensitivity testing and its clinical application in human gliomas.
Neurosurgical review 1989;12(3):197-203.
1988: Peter McLaughlin; W S Velasquez; J R Redman; W K Alfred Yung; F B Hagemeister; Maria A Rodriguez; Fernando Cabanillas
Chemotherapy with dexamethasone, high-dose cytarabine, and cisplatin for parenchymal brain lymphoma.
Journal of the National Cancer Institute 1988;80(17):1408-12.
1988: PA Steck; P Lee; Mien-Chie Hung; W K Alfred Yung
Expression of an altered epidermal growth factor receptor by human glioblastoma cells.
Cancer research 1988;48(19):5433-9.
1987: W K Alfred Yung; PA Steck; P J Kelleher; R P Moser; M G Rosenblum
Growth inhibitory effect of recombinant alpha and beta interferon on human glioma cells.
Journal of neuro-oncology 1987;5(4):323-30.