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Angelika Bröer

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Physiology

Biological Transport

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Disorders

Hartnup Disease

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Publications

TOP 3
I Moschen; Angelika Bröer; Sandra Galić; Florian Lang; Stefan Broer
Significance of short chain fatty acid transport by members of the monocarboxylate transporter family (MCT).
Stephen J Fairweather; Megan L O'Mara; Angelika Bröer; Stefan Broer
Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1.
Angelika Bröer; Charles G Bailey; Jeff Holst; Torsten Juelich; John Rasko; Peter S Solomon; Nadine Tietze; Jessica M Vanslambrouck; Stefan Broer
Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse.

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All Publications

2012: I Moschen; Angelika Bröer; Sandra Galić; Florian Lang; Stefan Broer
Significance of short chain fatty acid transport by members of the monocarboxylate transporter family (MCT).
Neurochemical research 2012;37(11):2562-8.
2012: Stephen J Fairweather; Megan L O'Mara; Angelika Bröer; Stefan Broer
Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1.
The Biochemical journal 2012;446(1):135-48.
2011: Angelika Bröer; Charles G Bailey; Jeff Holst; Torsten Juelich; John Rasko; Peter S Solomon; Nadine Tietze; Jessica M Vanslambrouck; Stefan Broer
Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse.
The Journal of biological chemistry 2011;286(30):26638-51.
2010: Sarojini Balkrishna; Angelika Bröer; Alice Kingsland; Stefan Broer
Rapid downregulation of the rat glutamine transporter SNAT3 by a caveolin-dependent trafficking mechanism in Xenopus laevis oocytes.
American journal of physiology. Cell physiology 2010;299(5):C1047-57.
2010: Jessica M Vanslambrouck; Angelika Bröer; Thuvaraka Thavyogarajah; Jeff Holst; Charles G Bailey; Stefan Bröer; John E J Rasko
Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria.
The Biochemical journal 2010;428(3):397-407.
2009: Stefan Broer; Hans-Peter Schneider; Angelika Bröer; Joachim W Deitmer
Mutation of asparagine 76 in the center of glutamine transporter SNAT3 modulates substrate-induced conductances and Na+ binding.
The Journal of biological chemistry 2009;284(38):25823-31.
2008: Stefan Broer; Charles G Bailey; Sonja Kowalczuk; Cynthia Ng; Jessica M Vanslambrouck; Helen Rodgers; Christiane Auray-Blais; Juleen A Cavanaugh; Angelika Bröer; John Rasko
Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters.
The Journal of clinical investigation 2008;118(12):3881-92.
2008: Sonja Kowalczuk; Angelika Bröer; Nadine Tietze; Jessica M Vanslambrouck; John Rasko; Stefan Broer
A protein complex in the brush-border membrane explains a Hartnup disorder allele.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(8):2880-7.
2007: Stefan Broer; Angelika Bröer; Jonas T Hansen; William A Bubb; Vladimir J Balcar; Fatima A Nasrallah; Brett Garner; Caroline Rae
Alanine metabolism, transport, and cycling in the brain.
Journal of neurochemistry 2007;102(6):1758-70.
2007: Hans-Peter Schneider; Stefan Broer; Angelika Bröer; Joachim W Deitmer
Heterologous expression of the glutamine transporter SNAT3 in Xenopus oocytes is associated with four modes of uncoupled transport.
The Journal of biological chemistry 2007;282(6):3788-98.
2006: Kevin Saliba; Rowena E Martin; Angelika Bröer; Roselani I Henry; C Siobhan McCarthy; Megan J Downie; Richard J W Allen; Kylie A Mullin; Geoffrey I McFadden; Stefan Broer; Kiaran Kirk
Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite.
Nature 2006;443(7111):582-5.
2006: Sarah Chubb; Alice L Kingsland; Angelika Bröer; Stefan Broer
Mutation of the 4F2 heavy-chain carboxy terminus causes y+ LAT2 light-chain dysfunction.
Molecular membrane biology 2006;23(3):255-67.
2006: Angelika Bröer; Nadine Tietze; Sonja Kowalczuk; Sarah Chubb; Michael Munzinger; Lasse K Bak; Stefan Broer
The orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2).
The Biochemical journal 2006;393(Pt 1):421-30.
2006: Angelika Bröer; Juleen A Cavanaugh; John Rasko; Stefan Broer
The molecular basis of neutral aminoacidurias.
Pflügers Archiv : European journal of physiology 2006;451(4):511-7.
2005: Christoph Böhmer; Angelika Bröer; Michael Munzinger; Sonja Kowalczuk; John Rasko; Florian Lang; Stefan Broer
Characterization of mouse amino acid transporter B0AT1 (slc6a19).
The Biochemical journal 2005;389(Pt 3):745-51.
2005: Sonja Kowalczuk; Angelika Bröer; Michael Munzinger; Nadine Tietze; Karin Klingel; Stefan Broer
Molecular cloning of the mouse IMINO system: an Na+- and Cl--dependent proline transporter.
The Biochemical journal 2005;386(Pt 3):417-22.
2004: Angelika Bröer; Joachim W Deitmer; Stefan Broer
Astroglial glutamine transport by system N is upregulated by glutamate.
Glia 2004;48(4):298-310.
2004: Vincent Berezowski; Dorota Miecz; Mariusz Marszałek; Angelika Bröer; Stefan Broer; Roméo Cecchelli; Katarzyna A Nałecz
Involvement of OCTN2 and B0,+ in the transport of carnitine through an in vitro model of the blood-brain barrier.
Journal of neurochemistry 2004;91(4):860-72.
2004: Heng F Seow; Stefan Broer; Angelika Bröer; Charles G Bailey; Simon J Potter; Juleen A Cavanaugh; John Rasko
Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19.
Nature genetics 2004;36(9):1003-7.
2004: Angelika Bröer; Karin Klingel; Sonja Kowalczuk; John Rasko; Juleen Cavanaugh; Stefan Broer
Molecular cloning of mouse amino acid transport system B0, a neutral amino acid transporter related to Hartnup disorder.
The Journal of biological chemistry 2004;279(23):24467-76.
2004: Manuel Pineda; Carsten A Wagner; Angelika Bröer; Paul A Stehberger; Simone Kaltenbach; Josep Lluis Gelpí; Rafael Martín Del Río; Antonio Zorzano; Manuel Palacín; Florian Lang; Stefan Broer
Cystinuria-specific rBAT(R365W) mutation reveals two translocation pathways in the amino acid transporter rBAT-b0,+AT.
The Biochemical journal 2004;377(Pt 3):665-74.
2003: Sandra Galić; Hans-Peter Schneider; Angelika Bröer; Joachim W Deitmer; Stefan Broer
The loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability.
The Biochemical journal 2003;376(Pt 2):413-22.
2003: Joachim W Deitmer; Angelika Bröer; Stefan Broer
Glutamine efflux from astrocytes is mediated by multiple pathways.
Journal of neurochemistry 2003;87(1):127-35.
2003: Tobias Heckel; Angelika Bröer; Heinrich Wiesinger; Florian Lang; Stefan Broer
Asymmetry of glutamine transporters in cultured neural cells.
Neurochemistry international 2003;43(4-5):289-98.
2003: Caroline Rae; Nathan Hare; William A Bubb; Sally R McEwan; Angelika Bröer; James A McQuillan; Vladimir J Balcar; Arthur D Conigrave; Stefan Broer
Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.
Journal of neurochemistry 2003;85(2):503-14.
2002: Angelika Bröer; Alexandra Albers; Iwan Setiawan; Robert H Edwards; Farrukh A Chaudhry; Florian Lang; Carsten A Wagner; Stefan Broer
Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions.
The Journal of physiology 2002;539(Pt 1):3-14.
2001: Alexandra Albers; Angelika Bröer; Carsten A Wagner; Iwan Setiawan; P A Lang; E U Kranz; Florian Lang; Stefan Broer
Na+ transport by the neural glutamine transporter ATA1.
Pflügers Archiv : European journal of physiology 2001;443(1):92-101.
2001: Angelika Bröer; B Friedrich; Carsten A Wagner; Sophie Fillon; Vadivel Ganapathy; Florian Lang; Stefan Broer
Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains.
The Biochemical journal 2001;355(Pt 3):725-31.
2000: Brigitte Pfeiffer-Guglielmi; Stefan Broer; Angelika Bröer; Bernd Hamprecht
Isozyme pattern of glycogen phosphorylase in the rat nervous system and rat astroglia-rich primary cultures: electrophoretic and polymerase chain reaction studies.
Neurochemical research 2000;25(11):1485-91.
2000: Carsten A Wagner; Ulrike Lükewille; Simone Kaltenbach; I Moschen; Angelika Bröer; Teut Risler; Stefan Broer; Florian Lang
Functional and pharmacological characterization of human Na(+)-carnitine cotransporter hOCTN2.
American journal of physiology. Renal physiology 2000;279(3):F584-91.
2000: Angelika Bröer; Carsten A Wagner; Florian Lang; Stefan Broer
The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine.
The Biochemical journal 2000;349 Pt 3():787-95.
2000: Carsten A Wagner; Angelika Bröer; Alexandra Albers; Nikita L Gamper; Florian Lang; Stefan Broer
The heterodimeric amino acid transporter 4F2hc/LAT1 is associated in Xenopus oocytes with a non-selective cation channel that is regulated by the serine/threonine kinase sgk-1.
The Journal of physiology 2000;526 Pt 1():35-46.
2000: Angelika Bröer; C Wagner; Florian Lang; Stefan Broer
Neutral amino acid transporter ASCT2 displays substrate-induced Na+ exchange and a substrate-gated anion conductance.
The Biochemical journal 2000;346 Pt 3():705-10.
1999: Angelika Bröer; Neville Brookes; Vadivel Ganapathy; K S Dimmer; Carsten A Wagner; Florian Lang; Stefan Broer
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux.
Journal of neurochemistry 1999;73(5):2184-94.
1999: B Rahman; Hans-Peter Schneider; Angelika Bröer; Joachim W Deitmer; Stefan Broer
Helix 8 and helix 10 are involved in substrate recognition in the rat monocarboxylate transporter MCT1.
Biochemistry 1999;38(35):11577-84.
1999: Stefan Broer; Angelika Bröer; Hans-Peter Schneider; C Stegen; A P Halestrap; Joachim W Deitmer
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes.
The Biochemical journal 1999;341 ( Pt 3)():529-35.
1998: J Pfeuffer; Stefan Broer; Angelika Bröer; M Lechte; U Flögel; Dieter Leibfritz
Expression of aquaporins in Xenopus laevis oocytes and glial cells as detected by diffusion-weighted 1H NMR spectroscopy and photometric swelling assay.
Biochimica et biophysica acta 1998;1448(1):27-36.
1998: Angelika Bröer; Bernd Hamprecht; Stefan Broer
Discrimination of two amino acid transport activities in 4F2 heavy chain- expressing Xenopus laevis oocytes.
The Biochemical journal 1998;333 ( Pt 3)():549-54.
1998: Stefan Broer; Hans-Peter Schneider; Angelika Bröer; B Rahman; Bernd Hamprecht; Joachim W Deitmer
Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH.
The Biochemical journal 1998;333 ( Pt 1)():167-74.
1998: Stefan Broer; A Schuster; Carsten A Wagner; Angelika Bröer; I Forster; J Biber; H Murer; A Werner; Florian Lang; Andreas E Busch
Chloride conductance and Pi transport are separate functions induced by the expression of NaPi-1 in Xenopus oocytes.
The Journal of membrane biology 1998;164(1):71-7.
1997: Stefan Broer; Angelika Bröer; Bernd Hamprecht
Expression of the surface antigen 4F2hc affects system-L-like neutral-amino-acid-transport activity in mammalian cells.
The Biochemical journal 1997;324 ( Pt 2)():535-41.
1995: Stefan Broer; Angelika Bröer; Bernd Hamprecht
The 4F2hc surface antigen is necessary for expression of system L-like neutral amino acid-transport activity in C6-BU-1 rat glioma cells: evidence from expression studies in Xenopus laevis oocytes.
The Biochemical journal 1995;312 ( Pt 3)():863-70.
1994: Stefan Broer; Angelika Bröer; Bernd Hamprecht
Expression of Na+-independent isoleucine transport activity from rat brain in Xenopus laevis oocytes.
Biochimica et biophysica acta 1994;1192(1):95-100.
1993: Stefan Broer; G Ji; Angelika Bröer; Simon Silver
Arsenic efflux governed by the arsenic resistance determinant of Staphylococcus aureus plasmid pI258.
Journal of bacteriology 1993;175(11):3480-5.