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Donald Zack

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Lars G Fritsche; Asbjorg Geirsdottir; Ronnie J George; Christian Gieger; Michael B Gorin; Neel Gupta; Robyn H Guymer; Gregory S Hageman; Stephanie A Hagstrom; Jonathan L Haines; Gregory Hannum; Simon P Harding; Christos Haritoglou; John R Heckenlively; Iris M Heid; Frank G Holz; Guy Hughes; Robert P Igo; John P A Ioannidis; Tatsuro Ishibashi; Sudha K Iyengar; Peronne Joseph; Gyungah Jun; Yoichiro Kamatani; Nicholas Katsanis; Jane C Khan; Ivana K Kim; Yutaka Kiyohara; Caroline C W Klaver; Barbara E K Klein; Michael L Klein; Ronald Klein; Jaclyn L Kovach; Igor Kozak; Michiaki Kubo; G Mark Lathrop; Clara J Lee; Kristine E Lee; Thierry Léveillard; Peter Lichtner; Andrew J Lotery; Thomas Meitinger; Joanna E Merriam; Paul Mitchell; Saddek Mohand-Saïd; Anthony T Moore; Denise J Morgan; Margaux A Morrison; Chelsea E Myers; Claudia N Keilhauer; Adam C Naj; Yusuke Nakamura; Yukinori Okada; Anton Orlin; M Carolina Ortube; Mohammad I Othman; Chris Pappas; Kyu Hyung Park; Gayle J T Pauer; Neal S Peachey; Margaret A Pericak-Vance; Olivier Poch; Rinki Ratna Priya; Robyn Reynolds; Andrea J Richardson; Stephan Ripke; Raymond Ripp; Guenther Rudolph; Euijung Ryu; José-Alain Sahel; Debra A Schaumberg; Hendrik P N Scholl; Matthew Schu; Stephen G Schwartz; William K Scott; Johanna M Seddon; Humma Shahid; Haraldur Sigurdsson; Giuliana Silvestri; Xueling Sim; Theru A Sivakumaran; R Theodore Smith; Lucia Sobrin; Eric H Souied; Dwight E Stambolian; Hreinn Stefansson; Kari Stefansson; Gwen M Sturgill-Short; Anand Swaroop; Atsushi Takahashi; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Nirubol Tosakulwong; Barbara J Truitt; Evangelia E Tsironi; André G Uitterlinden; Cornelia M van Duijn; Lingam Vijaya; Johannes R Vingerling; Eranga N Vithana; Jie Jin Wang; Bernhard H F Weber; Andrew R Webster; Daniel E Weeks; H-Erich Wichmann; Thomas W Winkler; Tien Y Wong; Alan F Wright; Brian L Yaspan; John R W Yates; Yi Yu; Donald J Zack; Diana Zelenika; Kang Zhang; Ming Zhang; Ling Zhao; Gonçalo R Abecasis; Anita Agarwal; Rando Allikmets; Satoshi Arakawa; Ana Maria Armbrecht; Isabelle Audo; Tin Aung; Paul N Baird; Gaetano R Barile; Mustapha Benchaboune; Alan C Bird; Paul N Bishop; Kari E Branham; Matthew Brooks; Alexander J Brucker; Gabriëlle H S Buitendijk; William H Cade; Melinda S Cain; Peter A Campochiaro; Chi-Chao Chan; Wei Chen; Ching-Yu Cheng; Emily Y Chew; Kimberly A Chin; Itay Chowers; Valentina Cipriani; David G Clayton; Radu Cojocaru; Yvette P Conley; Belinda K Cornes; Mark J Daly; Margaret M Deangelis; Baljean Dhillon; Albert O Edwards; Evangelos Evangelou; Jesen Fagerness; Lindsay A Farrer; Henry A Ferreyra; Peter J Francis; James S Friedman
Seven new loci associated with age-related macular degeneration.
Derek S Welsbie; Tian Xue; Zhiyong Yang; King-Wai Yau; Xinrong Zhou; Douglas Auld; CYNTHIA BERLINICKE; Richard Blouin; Sanford L Boye; Li-hui Cao; Chung-ha O Davis; Aaron DiAntonio; Raymond A Enke; Jie Fu; John Fuller; Yan Ge; Lucie Germain; Laszlo Hackler; Bing Han; Justin Hanes; William W Hauswirth; Syu-ichi Hirai; James Inglese; Nicholas Marsh-Armstrong; Scott E Martin; Shannath L Merbs; Katherine L Mitchell; Judy V Nguyen; Robert W Nickells; Harry A Quigley; Caroline Simard-Bisson; Donald J Zack
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death.
Igor O Nasonkin; Jacob Nellissery; Verity F Oliver; Krushangi Patel; Rivka A Rachel; Enrique J Rodriguez-Boulan; Donald J Zack; Kapil Bharti; Matthew Brooks; Raymond A Enke; Robert N Fariss; Milan Jamrich; Kevin Lazo; Yun Z Le; Shannath L Merbs; Anand Swaroop
Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis.

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2013: Lars G Fritsche; Asbjorg Geirsdottir; Ronnie J George; Christian Gieger; Michael B Gorin; Neel Gupta; Robyn H Guymer; Gregory S Hageman; Stephanie A Hagstrom; Jonathan L Haines; Gregory Hannum; Simon P Harding; Christos Haritoglou; John R Heckenlively; Iris M Heid; Frank G Holz; Guy Hughes; Robert P Igo; John P A Ioannidis; Tatsuro Ishibashi; Sudha K Iyengar; Peronne Joseph; Gyungah Jun; Yoichiro Kamatani; Nicholas Katsanis; Jane C Khan; Ivana K Kim; Yutaka Kiyohara; Caroline C W Klaver; Barbara E K Klein; Michael L Klein; Ronald Klein; Jaclyn L Kovach; Igor Kozak; Michiaki Kubo; G Mark Lathrop; Clara J Lee; Kristine E Lee; Thierry Léveillard; Peter Lichtner; Andrew J Lotery; Thomas Meitinger; Joanna E Merriam; Paul Mitchell; Saddek Mohand-Saïd; Anthony T Moore; Denise J Morgan; Margaux A Morrison; Chelsea E Myers; Claudia N Keilhauer; Adam C Naj; Yusuke Nakamura; Yukinori Okada; Anton Orlin; M Carolina Ortube; Mohammad I Othman; Chris Pappas; Kyu Hyung Park; Gayle J T Pauer; Neal S Peachey; Margaret A Pericak-Vance; Olivier Poch; Rinki Ratna Priya; Robyn Reynolds; Andrea J Richardson; Stephan Ripke; Raymond Ripp; Guenther Rudolph; Euijung Ryu; José-Alain Sahel; Debra A Schaumberg; Hendrik P N Scholl; Matthew Schu; Stephen G Schwartz; William K Scott; Johanna M Seddon; Humma Shahid; Haraldur Sigurdsson; Giuliana Silvestri; Xueling Sim; Theru A Sivakumaran; R Theodore Smith; Lucia Sobrin; Eric H Souied; Dwight E Stambolian; Hreinn Stefansson; Kari Stefansson; Gwen M Sturgill-Short; Anand Swaroop; Atsushi Takahashi; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Nirubol Tosakulwong; Barbara J Truitt; Evangelia E Tsironi; André G Uitterlinden; Cornelia M van Duijn; Lingam Vijaya; Johannes R Vingerling; Eranga N Vithana; Jie Jin Wang; Bernhard H F Weber; Andrew R Webster; Daniel E Weeks; H-Erich Wichmann; Thomas W Winkler; Tien Y Wong; Alan F Wright; Brian L Yaspan; John R W Yates; Yi Yu; Donald J Zack; Diana Zelenika; Kang Zhang; Ming Zhang; Ling Zhao; Gonçalo R Abecasis; Anita Agarwal; Rando Allikmets; Satoshi Arakawa; Ana Maria Armbrecht; Isabelle Audo; Tin Aung; Paul N Baird; Gaetano R Barile; Mustapha Benchaboune; Alan C Bird; Paul N Bishop; Kari E Branham; Matthew Brooks; Alexander J Brucker; Gabriëlle H S Buitendijk; William H Cade; Melinda S Cain; Peter A Campochiaro; Chi-Chao Chan; Wei Chen; Ching-Yu Cheng; Emily Y Chew; Kimberly A Chin; Itay Chowers; Valentina Cipriani; David G Clayton; Radu Cojocaru; Yvette P Conley; Belinda K Cornes; Mark J Daly; Margaret M Deangelis; Baljean Dhillon; Albert O Edwards; Evangelos Evangelou; Jesen Fagerness; Lindsay A Farrer; Henry A Ferreyra; Peter J Francis; James S Friedman
Seven new loci associated with age-related macular degeneration.
Nature genetics 2013;45(4):433-9, 439e1-2.
2013: Derek S Welsbie; Tian Xue; Zhiyong Yang; King-Wai Yau; Xinrong Zhou; Douglas Auld; CYNTHIA BERLINICKE; Richard Blouin; Sanford L Boye; Li-hui Cao; Chung-ha O Davis; Aaron DiAntonio; Raymond A Enke; Jie Fu; John Fuller; Yan Ge; Lucie Germain; Laszlo Hackler; Bing Han; Justin Hanes; William W Hauswirth; Syu-ichi Hirai; James Inglese; Nicholas Marsh-Armstrong; Scott E Martin; Shannath L Merbs; Katherine L Mitchell; Judy V Nguyen; Robert W Nickells; Harry A Quigley; Caroline Simard-Bisson; Donald J Zack
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(10):4045-50.
2013: Igor O Nasonkin; Jacob Nellissery; Verity F Oliver; Krushangi Patel; Rivka A Rachel; Enrique J Rodriguez-Boulan; Donald J Zack; Kapil Bharti; Matthew Brooks; Raymond A Enke; Robert N Fariss; Milan Jamrich; Kevin Lazo; Yun Z Le; Shannath L Merbs; Anand Swaroop
Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis.
Development (Cambridge, England) 2013;140(6):1330-41.
2013: Stephen Lumayag; Daniel A Nicholson; Sanja Turturro; David Valle; Karl J Wahlin; P Dane Witmer; Nicola J Corbett; Colleen Cowan; Caroline E Haldin; Beatrix Kovacs; Peter E Larsen; Donald J Zack; Shunbin Xu
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(6):E507-16.
2013: Louis R Pasquale; Margaret A Pericak-Vance; Tony Realini; Douglas J Rhee; Julia E Richards; Joel S Schuman; Kuldev Singh; Douglas Vollrath; Robert N Weinreb; Gadi Wollstein; Brian L Yaspan; Donald J Zack; Kang Zhang; Wael Abdrabou; R Rand Allingham; Donald L Budenz; Teresa C Chen; Elizabeth Delbono; David S Friedman; Douglas Gaasterland; Terry Gaasterland; Cynthia L Grosskreutz; Jonathan L Haines; Michael A Hauser; Jae H Kang; Richard K Lee; Paul R Lichter; Yutao Liu; Stephanie J Loomis; Catherine A McCarty; Sayoko E Moroi; Lana M Olson; Janey L Wiggs
CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States.
American journal of ophthalmology 2013;155(2):342-353.e5.
2013: Robert H Newman; QIANG NI; Akhilesh Pandey; Tony Pawson; Hee-Sool Rho; Alexey G Ryazanov; Matthew Shirley; Benjamin E Turk; Crystal Woodard; George Wu; SHULI XIA; Zhi Xie; Donald J Zack; Jin Zhang; Heng Zhu; Jun Seop Jeong; Morris J Birnbaum; Seth Blackshaw; Hillary M Clark; Philip A Cole; Christopher Cooper; Kevin N Dalby; Stephen Desiderio; Xinxin Gao; Anne-Claude Gingras; Renu Goel; Jianfei Hu; Shaohui Hu; Woochang Hwang; Hongkai Ji; Stefan Knapp; Jimmy Lin; John Neiswinger; Jiang Qian
Construction of human activity-based phosphorylation networks.
Molecular systems biology 2013;9():655.
2012: Julien Maruotti; Thuzar Thein; Donald J Zack; Noriko Esumi
MITF-M, a 'melanocyte-specific' isoform, is expressed in the adult retinal pigment epithelium.
Pigment cell & melanoma research 2012;25(5):641-4.
2012: Lucia Sobrin; Eric H Souied; Perciliz L Tan; André G Uitterlinden; Cornelia M van Duijn; Johannes R Vingerling; Yi Yu; Donald J Zack; R Theodore Smith; Rando Allikmets; Paul N Baird; Gaetano R Barile; Timothy W Behrens; Tushar R Bhangale; Milam A Brantley; Gabriëlle H S Buitendijk; Peter A Campochiaro; Usha Chakravarthy; Kimberly A Chin; Mark J Daly; Jesen Fagerness; Robert R Graham; Ruth E Hogg; John Ioannidis; Nicholas Katsanis; Caroline C W Klaver; Aaron Y Lee; Nicolas Leveziel; Joanna E Merriam; Soumya Raychaudhuri; Robyn Reynolds; Andrea J Richardson; Stephan Ripke; Johanna M Seddon
Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.
Ophthalmology 2012;119(9):1874-85.
2012: CYNTHIA BERLINICKE; Christopher F Ackermann; Steve H Chen; Mikael Lindvall; Sahiti Myneni; Vimla L Patel; Christoph Schulze; Yakov Shafranovich; Jian Wang; Donald J Zack; G Steven Bova
High-content screening data management for drug discovery in a small- to medium-size laboratory: results of a collaborative pilot study focused on user expectations as indicators of effectiveness.
Journal of laboratory automation 2012;17(4):255-65.
2012: Megan Ulmer; Douglas Vollrath; Robert Weinreb; Janey L Wiggs; Gadi Wollstein; Brian L Yaspan; Terri Young; Donald J Zack; Kang Zhang; Felicia Hawthorne; Jae H Kang; Richard Lee; Jun Li; Paul R Lichter; Yutao Liu; Sayoko E Moroi; Ayse Bilge Ozel; Louis R Pasquale; Margaret Pericak-Vance; Anthony Realini; Julia E Richards; Joel Schuman; Kuldev Singh; R Rand Allingham; Allison Ashley-Koch; Donald L Budenz; David S Friedman; Douglas Gaasterland; Jonathan Haines; Michael A Hauser
Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia.
Investigative ophthalmology & visual science 2012;53(8):4468-74.
2012: Giedrius Kalesnykas; Ericka N Oglesby; Mary Ellen Pease; Matthew R Steinhart; Jing Tian; Donald J Zack; Cone Frances; Harry A Quigley
Retinal ganglion cell morphology after optic nerve crush and experimental glaucoma.
Investigative ophthalmology & visual science 2012;53(7):3847-57.
2012: Kimberly A Toops; Donald J Zack; CYNTHIA BERLINICKE; Robert W Nickells
Hydrocortisone stimulates neurite outgrowth from mouse retinal explants by modulating macroglial activity.
Investigative ophthalmology & visual science 2012;53(4):2046-61.
2012: Ericka Oglesby; Mary Ellen Pease; Harry A Quigley; Matthew R Steinhart; Jing Tian; Donald J Zack; Cone Frances; Giedrius Kalesnykas
Semi-automated, quantitative analysis of retinal ganglion cell morphology in mice selectively expressing yellow fluorescent protein.
Experimental eye research 2012;96(1):107-15.
2012: Woochang Hwang; Hongkai Ji; George Wu; Donald J Zack; Laszlo Hackler; Jiang Qian
Dynamics of regulatory networks in the developing mouse retina.
PloS one 2012;7(10):e46521.
2012: Laszlo Hackler; Tomohiro Masuda; Shannath L Merbs; Verity F Oliver; Donald J Zack
Use of laser capture microdissection for analysis of retinal mRNA/miRNA expression and DNA methylation.
Methods in molecular biology (Clifton, N.J.) 2012;884():289-304.
2012: Janey L Wiggs; Gadi Wollstein; Brian L Yaspan; Sachiko Yoneyama; Donald J Zack; Kang Zhang; Wael Abdrabou; R Rand Allingham; Wendy Brodeur; Donald L Budenz; Joseph Caprioli; Andrew Thomas Crenshaw; Kristy Crooks; Elizabeth Delbono; Kimberly F Doheny; Jason Ernst; Bao J Fan; David S Friedman; Douglas Gaasterland; Terry Gaasterland; Michael A Hauser; Jae H Kang; Manolis Kellis; Cathy Laurie; Richard Lee; Paul R Lichter; Yutao Liu; Stephanie Loomis; Tomohiro Masuda; Cathy McCarty; Felipe A Medeiros; Daniel Mirel; Sayoko E Moroi; David C Musch; Lana M Olson; Louis R Pasquale; Margaret Pericak-Vance; Anthony Realini; Julia E Richards; Frank W Rozsa; Joel Schuman; Kathleen Scott; Kuldev Singh; Joshua D Stein; Edward H Trager; Paul Vanveldhuisen; Douglas Vollrath; Dan Y Wang; Robert N Weinreb; Jonathan L Haines
Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.
PLoS genetics 2012;8(4):e1002654.
2012: Shannath L Merbs; Verity F Oliver; Jiang Qian; Jun Wan; Laszlo Hackler; Miriam A Khan; Donald J Zack
Cell-specific DNA methylation patterns of retina-specific genes.
PloS one 2012;7(3):e32602.
2011: Soumya Raychaudhuri; Robyn Reynolds; Stephan Ripke; Albert K Tai; Perciliz L Tan; Soumya Vemuri; Yi Yu; Donald J Zack; Betsy Campochiaro; Peter A Campochiaro; Kimberly Chin; Mark J Daly; Sivakumar Gowrisankar; Oleg Iartchouk; Nicholas Katsanis; Kate Montgomery; Johanna M Seddon
A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.
Nature genetics 2011;43(12):1232-6.
2011: Jun Wan; Donald J Zack; Kieron M Torres; Laszlo Hackler; Tomohiro Masuda; Shannath L Merbs; Jiang Qian
Dynamic usage of alternative splicing exons during mouse retina development.
Nucleic acids research 2011;39(18):7920-30.
2011: Yi Yu; Donald J Zack; Haraldur Sigurdsson; R Theodore Smith; Lucia Sobrin; Eric H Souied; Kari Stefansson; Perciliz L Tan; Gudmar Thorleifsson; Unnur Thorsteinsdottir; André G Uitterlinden; Cornelia M van Duijn; Johannes R Vingerling; Rando Allikmets; Paul N Baird; Gaetano R Barile; timothy wayne behrens; Tushar R Bhangale; Milam A Brantley; Gabriëlle H S Buitendijk; Betsy Campochiaro; Peter A Campochiaro; Usha Chakravarthy; Kimberly A Chin; Mark J Daly; Evangelos Evangelou; Jesen Fagerness; Robert R Graham; Omar Gustafsson; Robyn H Guymer; Ruth Hogg; John Ioannidis; Nicholas Katsanis; Caroline C W Klaver; Aaron Y Lee; Phil H Lee; Nicolas Leveziel; Joanna E Merriam; Ward Ortmann; Soumya Raychaudhuri; Robyn Reynolds; Andrea J Richardson; Stephan Ripke; Luba D Robman; Johanna M Seddon
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.
Human molecular genetics 2011;20(18):3699-709.
2011: Zhiyong Yang; Donald J Zack
What has gene expression profiling taught us about glaucoma?
Experimental eye research 2011;93(2):191-5.
2011: Harry A Quigley; Cone Frances; Scott E Gelman; Zhiyong Yang; Janice L Son; Ericka N Oglesby; Mary Ellen Pease; Donald J Zack
Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice.
Experimental eye research 2011;92(4):299-305.
2011: Jared Iacovelli; Chen Zhao; Natalie Wolkow; Peter Veldman; Kandace Gollomp; Pallavi Ojha; Nina Lukinova; Ayala King; Leonard Feiner; Noriko Esumi; Donald J Zack; Eric A Pierce; Douglas Vollrath; Joshua L Dunaief
Generation of Cre transgenic mice with postnatal RPE-specific ocular expression.
Investigative ophthalmology & visual science 2011;52(3):1378-83.
2011: J. SAMUEL ZIGLER; Cheng Zhang; Rhonda Grebe; Gitanjali Sehrawat; Laszlo Hackler; Souvonik Adhya; Stacey Hose; D Scott McLeod; Imran A Bhutto; Walid Khaled Barbour; Geetha Parthasarathy; Donald J Zack; Yuri V Sergeev; Gerard A Lutty; James T Handa; Debasish Sinha
Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.
Journal of cell science 2011;124(Pt 4):523-31.
2011: Wolfgang Baehr; Ted Wensel; Greg Hageman; Sam Wu; Donald J Zack
Retinal ganglion cells: development, function, and disease.
Vision research 2011;51(2):223.
2011: Judy V Nguyen; Ileana Soto; Keun-Young Kim; Eric A Bushong; Ericka Oglesby; Francisco J Valiente-Soriano; Zhiyong Yang; Chung-ha O Davis; Joseph L Bedont; Janice L Son; John O Wei; Vladimir L Buchman; Donald J Zack; Vidal-Sanz Manuel; Mark H Ellisman; Nicholas Marsh-Armstrong
Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(3):1176-81.
2010: Karl Wahlin; Laszlo Hackler; Ruben Adler; Donald J Zack
Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina.
The Journal of comparative neurology 2010;518(24):4938-62.
2010: Jianfei Hu; Jun Wan; Laszlo Hackler; Donald J Zack; Jiang Qian
Computational analysis of tissue-specific gene networks: application to murine retinal functional studies.
Bioinformatics (Oxford, England) 2010;26(18):2289-97.
2010: Mali Jiang; Yair Porat-Shliom; Zhong Pei; Yong Cheng; Lan Xiang; Katherine Sommers; Qing Li; Frank Gillardon; Bastian Hengerer; CYNTHIA BERLINICKE; Wanli Smith; Donald J Zack; Michelle A Poirier; Christopher A Ross; WENZHEN DUAN
Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism.
Journal of neurochemistry 2010;114(2):419-29.
2010: Akiko Miki; Katsuaki Miki; Shinji Ueno; Delphine M Bonnet Wersinger; CYNTHIA BERLINICKE; Gillian C Shaw; Shinichi Usui; Yuxia Wang; Donald J Zack; Peter A Campochiaro
Prolonged blockade of VEGF receptors does not damage retinal photoreceptors or ganglion cells.
Journal of cellular physiology 2010;224(1):262-72.
2010: Sheikh Amer Riazuddin; Muhammad Iqbal; Yue Wang; Tomohiro Masuda; Yuhng Chen; Sara Bowne; Lori S Sullivan; Naushin H Waseem; Shomi Bhattacharya; Stephen P Daiger; Kang Zhang; Shaheen N Khan; Sheikh Riazuddin; J Fielding Hejtmancik; Paul Sieving; Donald J Zack; Nicholas Katsanis
A splice-site mutation in a retina-specific exon of BBS8 causes nonsyndromic retinitis pigmentosa.
American journal of human genetics 2010;86(5):805-12.
2010: Benjamin M Neale; Jesen Fagerness; Robyn Reynolds; Lucia Sobrin; Margaret Parker; Soumya Raychaudhuri; Perciliz L Tan; Edwin C Oh; Joanna E Merriam; Eric Souied; Paul S Bernstein; Binxing Li; Jeanne M Frederick; Kang Zhang; Milam A Brantley; Aaron Y Lee; Donald J Zack; Betsy Campochiaro; Peter A Campochiaro; Stephan Ripke; R Theodore Smith; Gaetano R Barile; Nicholas Katsanis; Rando Allikmets; Mark J Daly; Johanna M Seddon
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).
Proceedings of the National Academy of Sciences of the United States of America 2010;107(16):7395-400.
2010: Wei Chen; Dwight Stambolian; Albert O Edwards; Kari E H Branham; Mohammad Othman; Johanna Jakobsdottir; Nirubol Tosakulwong; Margaret Pericak-Vance; Peter A Campochiaro; Michael L Klein; Perciliz L Tan; Yvette P Conley; Atsuhiro Kanda; Laura Kopplin; Yanming Li; Katherine J Augustaitis; Athanasios J Karoukis; William Scott; Anita Agarwal; Jaclyn Kovach; Stephen Schwartz; Eric A Postel; Matthew Brooks; Keith H Baratz; William L Brown; Alexander J Brucker; Anton Orlin; Gary Brown; Allen Ho; Carl Regillo; Larry Donoso; Lifeng Tian; Brian Kaderli; Dexter Hadley; Stephanie A Hagstrom; Neal S Peachey; Ronald Klein; Barbara E K Klein; Gotoh Norimoto; Kenji Yamashiro; Frederick Ferris Iii; Jesen A Fagerness; Robyn Reynolds; Lindsay A Farrer; Ivana K Kim; Joan W Miller; Marta Cortón; Angel Carracedo; Manuel Sanchez-Salorio; Elizabeth W Pugh; Kimberly F Doheny; Maria Brion; Margaret M Deangelis; Daniel E Weeks; Donald J Zack; Emily Y Chew; John R Heckenlively; Nagahisa Yoshimura; Sudha K Iyengar; Peter J Francis; Nicholas Katsanis; Johanna M Seddon; Jonathan L Haines; Michael B Gorin; Gonçalo R Abecasis; Anand Swaroop
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(16):7401-6.
2010: Laszlo Hackler; Jun Wan; Anand Swaroop; Jiang Qian; Donald J Zack
MicroRNA profile of the developing mouse retina.
Investigative ophthalmology & visual science 2010;51(4):1823-31.
2010: Zhenglin Yang; Zongzhong Tong; Yuhong Chen; Jiexi Zeng; Fang Lu; Xufang Sun; Chao Zhao; Kevin Wang; Lisa Davey; Haoyu Chen; Nyall London; Daisuke Muramatsu; Francesca Salasar; Ruben Carmona; Daniel Kasuga; Xiaolei Wang; Matthew Bedell; Manjuxia Dixie; Peiquan Zhao; Ruifu Yang; Daniel Gibbs; Xiaoqi Liu; Yan Li; Cai Li; Yuanfeng Li; Betsy Campochiaro; Ryan Constantine; Donald J Zack; Peter A Campochiaro; Yinbin Fu; Dean Y Li; Nicholas Katsanis; Kang Zhang
Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration.
PLoS genetics 2010;6(2):e1000836.
2010: Sacha Reichman; Ravi Kiran Reddy Kalathur; Sophie Lambard; Najate Aït-Ali; Yanjiang Yang; Aurélie Lardenois; Raymond Ripp; Olivier Poch; Donald J Zack; José-Alain Sahel; Thierry Léveillard
The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina.
Human molecular genetics 2010;19(2):250-61.
2010: Sophie Lambard; Sacha Reichman; CYNTHIA BERLINICKE; Marie-Laure Niepon; Olivier Goureau; José-Alain Sahel; Thierry Léveillard; Donald J Zack
Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity.
PloS one 2010;5(10):e13075.
2009: Yuqin Yin; Qi Cui; Hui-Ya Gilbert; Yang Yang; Zhiyong Yang; CYNTHIA BERLINICKE; Zhiwei Li; Camila Zaverucha-do-Valle; Huamei He; Victoria Petkova; Donald J Zack; Larry I Benowitz
Oncomodulin links inflammation to optic nerve regeneration.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19587-92.
2009: Jun Wan; Jimmy Lin; Donald J Zack; Jiang Qian
Relating periodicity of nucleosome organization and gene regulation.
Bioinformatics (Oxford, England) 2009;25(14):1782-8.
2009: Mary Ellen Pease; Donald J Zack; CYNTHIA BERLINICKE; Kristen Bloom; Cone Frances; Yuxia Wang; Ronald L. Klein; William W Hauswirth; Harry A Quigley
Effect of CNTF on retinal ganglion cell survival in experimental glaucoma.
Investigative ophthalmology & visual science 2009;50(5):2194-200.
2009: Noriko Esumi; Shu Kachi; Laszlo Hackler; Tomohiro Masuda; Zhiyong Yang; Peter A Campochiaro; Donald J Zack
BEST1 expression in the retinal pigment epithelium is modulated by OTX family members.
Human molecular genetics 2009;18(1):128-41.
2008: Xueping Yu; Jimmy Lin; Donald J Zack; Joshua T Mendell; Jiang Qian
Analysis of regulatory network topology reveals functionally distinct classes of microRNAs.
Nucleic acids research 2008;36(20):6494-503.
2008: Zhenglin Yang; Charity Stratton; Peter J Francis; Mark E Kleinman; Perciliz L Tan; Daniel Gibbs; Zongzhong Tong; Haoyu Chen; Ryan Constantine; Xian Yang; Yuhong Chen; Jiexi Zeng; Lisa Davey; Xiang Ma; Vincent S Hau; Chi Wang; Jennifer Harmon; Jeanette Buehler; Erik Pearson; Shrena Patel; Yuuki Kaminoh; Scott Watkins; Ling Luo; Norman A Zabriskie; Paul S Bernstein; Wongil Cho; Andrea Schwager; David R Hinton; Michael L Klein; Sara C Hamon; Emily Simmons; Beifeng Yu; Betsy Campochiaro; Janet S Sunness; Peter A Campochiaro; Lynn Jorde; Giovanni Parmigiani; Donald J Zack; Nicholas Katsanis; Jayakrishna Ambati; Kang Zhang
Toll-like receptor 3 and geographic atrophy in age-related macular degeneration.
The New England journal of medicine 2008;359(14):1456-63.
2008: Shinji Ueno; Mary Ellen Pease; Delphine M Bonnet Wersinger; Tomohiro Masuda; Stanley A Vinores; Tamar Licht; Donald J Zack; Harry A Quigley; Eli Keshet; Peter A Campochiaro
Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels.
Journal of cellular physiology 2008;217(1):13-22.
2008: Yun-Zheng Le; Wei Zheng; Pengcheng Rao; Lixing Zheng; Robert E Anderson; Noriko Esumi; Donald J Zack; Meili Zhu
Inducible expression of cre recombinase in the retinal pigmented epithelium.
Investigative ophthalmology & visual science 2008;49(3):1248-53.
2008: Itay Chowers; Tal Meir; Michal Lederman; Nitza Goldenberg-Cohen; Yoram Cohen; Eyal Banin; Edward Averbukh; Itzhak Hemo; Ayala Pollack; Ruth Axer-Siegel; Orly Weinstein; Josephine Hoh; Donald J Zack; Tural Galbinur
Sequence variants in HTRA1 and LOC387715/ARMS2 and phenotype and response to photodynamic therapy in neovascular age-related macular degeneration in populations from Israel.
Molecular vision 2008;14():2263-71.
2008: Xiong Liu; Xueping Yu; Donald J Zack; Heng Zhu; Jiang Qian
TiGER: a database for tissue-specific gene expression and regulation.
BMC bioinformatics 2008;9():271.
2008: Debasish Sinha; Andrew Klise; Yuri V Sergeev; Stacey Hose; Imran A Bhutto; Laszlo Hackler; Tanya Malpic-Llanos; Sonia Samtani; Rhonda Grebe; Morton F Goldberg; J Fielding Hejtmancik; Avindra Nath; Donald J Zack; Robert Fariss; D Scott McLeod; Olof H Sundin; Karl W Broman; Gerard A Lutty; J. SAMUEL ZIGLER
betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development.
Molecular and cellular neurosciences 2008;37(1):85-95.
2007: Zhiyong Yang; Harry A Quigley; Mary Ellen Pease; Yanqin Yang; Jiang Qian; Danielle Valenta; Donald J Zack
Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms.
Investigative ophthalmology & visual science 2007;48(12):5539-48.
2007: Hangxiu Xu; Drina D Sta Iglesia; Jennifer Kielczewski; Danielle Valenta; Mary Ellen Pease; Donald J Zack; Harry A Quigley
Characteristics of progenitor cells derived from adult ciliary body in mouse, rat, and human eyes.
Investigative ophthalmology & visual science 2007;48(4):1674-82.
2007: Noriko Esumi; Shu Kachi; Peter A Campochiaro; Donald J Zack
VMD2 promoter requires two proximal E-box sites for its activity in vivo and is regulated by the MITF-TFE family.
The Journal of biological chemistry 2007;282(3):1838-50.
2007: Guiyuan Li; Robert E Anderson; Hiroshi Tomita; Ruben Adler; Xiaochun Liu; Donald J Zack; Raju V S Rajala
Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(1):203-11.
2007: Xueping Yu; Jimmy Lin; Donald J Zack; Jiang Qian
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors.
BMC bioinformatics 2007;8():437.
2007: John B Kerrison; Donald J Zack
Neurite outgrowth in retinal ganglion cell culture.
Methods in molecular biology (Clifton, N.J.) 2007;356():427-34.
2006: Jiang Qian; Jimmy Lin; Donald J Zack
Characterization of binding sites of eukaryotic transcription factors.
Genomics, proteomics & bioinformatics 2006;4(2):67-79.
2006: Itay Chowers; Robert Wong; Tzvete Dentchev; Ronald H Farkas; Jared Iacovelli; Tushara L Gunatilaka; Nancy E Medeiros; J Brett Presley; Peter A Campochiaro; Christine A Curcio; Joshua L Dunaief; Donald J Zack
The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration.
Investigative ophthalmology & visual science 2006;47(5):2135-40.
2006: Shu Kachi; Noriko Esumi; Donald J Zack; Peter A Campochiaro
Sustained expression after nonviral ocular gene transfer using mammalian promoters.
Gene therapy 2006;13(9):798-804.
2006: Kimberley M Dorval; Brian P Bobechko; Hiroki Fujieda; Shiming Chen; Donald J Zack; Rod Bremner
CHX10 targets a subset of photoreceptor genes.
The Journal of biological chemistry 2006;281(2):744-51.
2006: Jimmy Lin; Donald J Zack; Jiang Qian
Transcriptional regulatory network prediction.
Biotechnology & genetic engineering reviews 2006;22():45-62.
2006: Xueping Yu; Jimmy Lin; Donald J Zack; Jiang Qian
Computational analysis of tissue-specific combinatorial gene regulation: predicting interaction between transcription factors in human tissues.
Nucleic acids research 2006;34(17):4925-36.
2006: Xueping Yu; Jimmy Lin; Tomohiro Masuda; Noriko Esumi; Donald J Zack; Jiang Qian
Genome-wide prediction and characterization of interactions between transcription factors in Saccharomyces cerevisiae.
Nucleic acids research 2006;34(3):917-27.
2005: Rebecca L Bradford; Chenwei Wang; Donald J Zack; Ruben Adler
Roles of cell-intrinsic and microenvironmental factors in photoreceptor cell differentiation.
Developmental biology 2005;286(1):31-45.
2005: John B Kerrison; Elia J Duh; Yilin Yu; Deborah C Otteson; Donald J Zack
A system for inducible gene expression in retinal ganglion cells.
Investigative ophthalmology & visual science 2005;46(8):2932-9.
2005: Yuji Oshima; Sachiko Oshima; Hiroyuki Nambu; Shu Kachi; Kyoichi Takahashi; Naoyasu Umeda; Jikui Shen; Aling Dong; Rajendra S Apte; Elia J Duh; Sean F Hackett; Godwin Okoye; Kazuki Ishibashi; James T Handa; Michele Melia; Stanley J Wiegand; George D Yancopoulos; Donald J Zack; Peter A Campochiaro
Different effects of angiopoietin-2 in different vascular beds: new vessels are most sensitive.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(8):963-5.
2005: Shu Kachi; Y Oshima; Noriko Esumi; M Kachi; Brian Rogers; Donald J Zack; Peter A Campochiaro
Nonviral ocular gene transfer.
Gene therapy 2005;12(10):843-51.
2005: Deborah C Otteson; Motokazu Tsujikawa; Tushara L Gunatilaka; Jarema Malicki; Donald J Zack
Genomic organization of zebrafish cone-rod homeobox gene and exclusion as a candidate gene for retinal degeneration in niezerka and mikre oko.
Molecular vision 2005;11():986-95.
2005: Jiang Qian; Noriko Esumi; Yangjian Chen; Qingliang Wang; Itay Chowers; Donald J Zack
Identification of regulatory targets of tissue-specific transcription factors: application to retina-specific gene regulation.
Nucleic acids research 2005;33(11):3479-91.
2005: Deborah C Otteson; Hong Lai; Yuhui Liu; Donald J Zack
Zinc-finger domains of the transcriptional repressor KLF15 bind multiple sites in rhodopsin and IRBP promoters including the CRS-1 and G-rich repressor elements.
BMC molecular biology 2005;6():15.
2005: John B Kerrison; Robert N Lewis; Deborah C Otteson; Donald J Zack
Bone morphogenetic proteins promote neurite outgrowth in retinal ganglion cells.
Molecular vision 2005;11():208-15.
2004: Yuji Oshima; Sachiko Oshima; Hiroyuki Nambu; Shu Kachi; Sean F Hackett; Michele Melia; Michael Kaleko; Sheila Connelly; Noriko Esumi; Donald J Zack; Peter A Campochiaro
Increased expression of VEGF in retinal pigmented epithelial cells is not sufficient to cause choroidal neovascularization.
Journal of cellular physiology 2004;201(3):393-400.
2004: Abigail S Hackam; Richelle Strom; Dongmei Liu; Jiang Qian; Chenwei Wang; Deborah C Otteson; Tushara L Gunatilaka; Ronald H Farkas; Itay Chowers; Masaaki Kageyama; Thierry Leveillard; José-Alain Sahel; Peter A Campochiaro; Giovanni Parmigiani; Donald J Zack
Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse.
Investigative ophthalmology & visual science 2004;45(9):2929-42.
2004: Abigail S Hackam; Jiang Qian; Dongmei Liu; Tushara L Gunatilaka; Ronald H Farkas; Itay Chowers; Masaaki Kageyama; Giovanni Parmigiani; Donald J Zack
Comparative gene expression analysis of murine retina and brain.
Molecular vision 2004;10():637-49.
2004: Deborah C Otteson; Yuhui Liu; Hong Lai; ChenWei Wang; Susan Gray; Mukesh K Jain; Donald J Zack
Kruppel-like factor 15, a zinc-finger transcriptional regulator, represses the rhodopsin and interphotoreceptor retinoid-binding protein promoters.
Investigative ophthalmology & visual science 2004;45(8):2522-30.
2004: Ronald H Farkas; Jiang Qian; Jeffrey L. Goldberg; Harry A Quigley; Donald J Zack
Gene expression profiling of purified rat retinal ganglion cells.
Investigative ophthalmology & visual science 2004;45(8):2503-13.
2004: Sepideh Zareparsi; Alfred O Hero; Donald J Zack; Robert W Williams; Anand Swaroop
Seeing the unseen: Microarray-based gene expression profiling in vision.
Investigative ophthalmology & visual science 2004;45(8):2457-62.
2004: Itay Chowers; Yoonhee Kim; Ronald H Farkas; Tushara L Gunatilaka; Abigail S Hackam; Peter A Campochiaro; Silvia C Finnemann; Donald J Zack
Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake.
Investigative ophthalmology & visual science 2004;45(7):2098-106.
2004: Karl Wahlin; Lynette Lim; Elizabeth A Grice; Peter A Campochiaro; Donald J Zack; Ruben Adler
A method for analysis of gene expression in isolated mouse photoreceptor and Müller cells.
Molecular vision 2004;10():366-75.
2004: Zhenglin Yang; Yang Li; Li Jiang; Goutam Karan; Darius M Moshfeghi; Scott O'Connor; Xi Li; Zhengya Yu; Hilel Lewis; Donald J Zack; Samuel Jacobson; Kang Zhang
A novel RDS/peripherin gene mutation associated with diverse macular phenotypes.
Ophthalmic genetics 2004;25(2):133-45.
2004: Qing-liang Wang; Shiming Chen; Noriko Esumi; Prabodh K Swain; Heidi S Haines; Guanghua Peng; B Michele Melia; Iain McIntosh; John R Heckenlively; Samuel G Jacobson; Edwin M Stone; Anand Swaroop; Donald J Zack
QRX, a novel homeobox gene, modulates photoreceptor gene expression.
Human molecular genetics 2004;13(10):1025-40.
2004: Steven J Pittler; Youwen Zhang; Shiming Chen; Alan J Mears; Donald J Zack; Zhiyong Ren; Prabodh K Swain; Suxia Yao; Anand Swaroop; J Brandon White
Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity.
The Journal of biological chemistry 2004;279(19):19800-7.
2004: Ronald H Farkas; Itay Chowers; Abigail S Hackam; Masaaki Kageyama; Robert W Nickells; Deborah C Otteson; Elia J Duh; Chenwei Wang; Danielle Valenta; Tushara L Gunatilaka; Mary Ellen Pease; Harry A Quigley; Donald J Zack
Increased expression of iron-regulating genes in monkey and human glaucoma.
Investigative ophthalmology & visual science 2004;45(5):1410-7.
2004: Hiroyuki Nambu; Rie Nambu; Yuji Oshima; Sean F Hackett; Godwin Okoye; Stanley J Wiegand; George D Yancopoulos; Donald J Zack; Peter A Campochiaro
Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier.
Gene therapy 2004;11(10):865-73.
2004: Noriko Esumi; Yuji Oshima; Yuanyuan Li; Peter A Campochiaro; Donald J Zack
Analysis of the VMD2 promoter and implication of E-box binding factors in its regulation.
The Journal of biological chemistry 2004;279(18):19064-73.
2004: Elia J Duh; Hoseong S Yang; Julia A Haller; Eugene de JUAN; Mark S Humayun; Peter L Gehlbach; Michele Melia; Dante J Pieramici; JOSEPH HARLAN; Peter A Campochiaro; Donald J Zack
Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis.
American journal of ophthalmology 2004;137(4):668-74.
2004: Itay Chowers; Noriko Esumi; Peter A Campochiaro; Donald J Zack
Studies on retinal and retinal pigment epithelial gene expression.
Novartis Foundation symposium 2004;255():131-45; discussion 145-6, 177-8.
2003: Itay Chowers; Dongmei Liu; Ronald H Farkas; Tushara L Gunatilaka; Abigail S Hackam; Steven L Bernstein; Peter A Campochiaro; Giovanni Parmigiani; Donald J Zack
Gene expression variation in the adult human retina.
Human molecular genetics 2003;12(22):2881-93.
2003: Keith R G Martin; Harry A Quigley; Donald J Zack; Hana Levkovitch-Verbin; Jennifer Kielczewski; Danielle Valenta; Lisa A Baumrind; Mary Ellen Pease; Ronald L. Klein; William W Hauswirth
Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.
Investigative ophthalmology & visual science 2003;44(10):4357-65.
2003: Itay Chowers; Tushara L Gunatilaka; Ronald H Farkas; Jiang Qian; Abigail S Hackam; Elia J Duh; Masaaki Kageyama; Chenwei Wang; Amit Vora; Peter A Campochiaro; Donald J Zack
Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray.
Investigative ophthalmology & visual science 2003;44(9):3732-41.
2003: Hana Levkovitch-Verbin; Harry A Quigley; Keith R G Martin; Donald J Zack; Mary Ellen Pease; Danielle Valenta
A model to study differences between primary and secondary degeneration of retinal ganglion cells in rats by partial optic nerve transection.
Investigative ophthalmology & visual science 2003;44(8):3388-93.
2003: Abigail S Hackam; Rebecca L Bradford; Rita N Bakhru; Raza M Shah; Ronald H Farkas; Donald J Zack; Ruben Adler
Gene discovery in the embryonic chick retina.
Molecular vision 2003;9():262-76.
2003: Godwin Okoye; Joelle Zimmer; Jennifer U Sung; Peter L Gehlbach; Tye Deering; Hiroyuki Nambu; Sean F Hackett; Michele Melia; Noriko Esumi; Donald J Zack; Peter A Campochiaro
Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(10):4164-72.
2003: Michael J Pianta; Tomas S Aleman; Artur Vahe Cideciyan; Janet S Sunness; Yuanyuan Li; Betsy A Campochiaro; Peter A Campochiaro; Donald J Zack; Edwin M Stone; Samuel G Jacobson
In vivo micropathology of Best macular dystrophy with optical coherence tomography.
Experimental eye research 2003;76(2):203-11.
2002: Anand Swaroop; Donald J Zack
Transcriptome analysis of the retina.
Genome biology 2002;3(8):REVIEWS1022.
2002: Shiwani Sharma; Jinghua T Chang; Neil G Della; Peter A Campochiaro; Donald J Zack
Identification of novel bovine RPE and retinal genes by subtractive hybridization.
Molecular vision 2002;8():251-8.
2002: Keisuke Mori; Peter L Gehlbach; Satoru Yamamoto; Elia J Duh; Donald J Zack; Quihong Li; Kenneth I Berns; Brian J Raisler; William W Hauswirth; Peter A Campochiaro
AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization.
Investigative ophthalmology & visual science 2002;43(6):1994-2000.
2002: Joshua L Dunaief; Ayala King; Noriko Esumi; Matthew Eagen; Tzvete Dentchev; Ching-Hwa Sung; Shiming Chen; Donald J Zack
Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo.
Current eye research 2002;24(5):392-6.
2002: Shiming Chen; Qing-Liang Wang; Siqun Xu; Ivy Liu; Lili Y Li; Yufang Wang; Donald J Zack
Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy.
Human molecular genetics 2002;11(8):873-84.
2002: Kang Zhang; Daniel C Garibaldi; Yang Li; W Richard Green; Donald J Zack
Butterfly-shaped pattern dystrophy: a genetic, clinical, and histopathological report.
Archives of ophthalmology 2002;120(4):485-90.
2002: Stuart J McKinnon; Donna Lehman; Lisa A Kerrigan-Baumrind; Carol Merges; Mary Ellen Pease; Danielle F Kerrigan; Nancy L Ransom; N Grace Tahzib; Herbert A Reitsamer; Hana Levkovitch-Verbin; Harry A Quigley; Donald J Zack
Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.
Investigative ophthalmology & visual science 2002;43(4):1077-87.
2002: Elia J Duh; Hoseong S Yang; Izumi Suzuma; Masaru Miyagi; Elaine Youngman; Keisuke Mori; Miyuki Katai; Lin Yan; Kiyoshi Suzuma; Karen West; Shekar Davarya; Patrick Tong; Peter L Gehlbach; Joel R Pearlman; John W Crabb; Lloyd Paul Aiello; Peter A Campochiaro; Donald J Zack
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth.
Investigative ophthalmology & visual science 2002;43(3):821-9.
2002: Kyoko Ohno-Matsui; Akira Hirose; Satoru Yamamoto; Jina Saikia; Naoyuki Okamoto; Peter L Gehlbach; Elia J Duh; Sean F Hackett; Michelle Chang; Dean Bok; Donald J Zack; Peter A Campochiaro
Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment.
The American journal of pathology 2002;160(2):711-9.
2002: Rizgar A Mageed; Donald J Zack
Cross-reactivity and pathogenicity of anti-DNA autoantibodies in systemic lupus erythematosus.
Lupus 2002;11(12):783-6.
2001: Karl Wahlin; Ruben Adler; Donald J Zack; Peter A Campochiaro
Neurotrophic signaling in normal and degenerating rodent retinas.
Experimental eye research 2001;73(5):693-701.
2001: Haruhiko Yamada; Eri Yamada; Akira Ando; Noriko Esumi; N Bora; Jina Saikia; C H Sung; Donald J Zack; Peter A Campochiaro
Fibroblast growth factor-2 decreases hyperoxia-induced photoreceptor cell death in mice.
The American journal of pathology 2001;159(3):1113-20.
2001: Susan E Wilkie; Y Li; Evelyne C Deery; Richard J Newbold; D Garibaldi; J B Bateman; H Zhang; W Lin; Donald J Zack; Shomi S Bhattacharya; Martin J Warren; David Hunt; Kang Zhang
Identification and functional consequences of a new mutation (E155G) in the gene for GCAP1 that causes autosomal dominant cone dystrophy.
American journal of human genetics 2001;69(3):471-80.
2001: Keisuke Mori; Elia J Duh; Peter L Gehlbach; Akira Ando; Kyoichi Takahashi; Joel R Pearlman; K Mori; Hoseong S Yang; Donald J Zack; Damodar Ettyreddy; Douglas E Brough; Lisa L Wei; Peter A Campochiaro
Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization.
Journal of cellular physiology 2001;188(2):253-63.
2001: Radouil T Tzekov; Y Liu; Melanie M Sohocki; Donald J Zack; Stephen P Daiger; John R Heckenlively; David G Birch
Autosomal dominant retinal degeneration and bone loss in patients with a 12-bp deletion in the CRX gene.
Investigative ophthalmology & visual science 2001;42(6):1319-27.
2001: W Yan; G F Jang; Francoise Haeseleer; Noriko Esumi; J Chang; M Kerrigan; M Campochiaro; Peter A Campochiaro; Krzysztof Palczewski; Donald J Zack
Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium.
Genomics 2001;72(2):193-202.
2001: Masahiko Shimura; Yukun Yuan; J T Chang; S Zhang; Peter A Campochiaro; Donald J Zack; Bret A Hughes
Expression and permeation properties of the K(+) channel Kir7.1 in the retinal pigment epithelium.
The Journal of physiology 2001;531(Pt 2):329-46.
2001: Yuhui Liu; Y Shen; J S Rest; P A Raymond; Donald J Zack
Isolation and characterization of a zebrafish homologue of the cone rod homeobox gene.
Investigative ophthalmology & visual science 2001;42(2):481-7.
2001: Eri Yamada; T Tobe; Haruhiko Yamada; Naoyuki Okamoto; Donald J Zack; Z Werb; P D Soloway; Peter A Campochiaro
TIMP-1 promotes VEGF-induced neovascularization in the retina.
Histology and histopathology 2001;16(1):87-97.
2001: Kang Zhang; MF Kniazeva; Min Han; W Li; Z Yu; Zhenglin Yang; Yingying Li; Michael Metzker; Rando Allikmets; Donald J Zack; Laura E Kakuk; Pamela S Lagali; Paul W Wong; Ian M MacDonald; Paul Sieving; David Figueroa; Christopher P Austin; Robert Gould; Radha Ayyagari; Konstantin Petrukhin
A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy.
Nature genetics 2001;27(1):89-93.
2000: M A Chang; J W Horner; Bruce R Conklin; Ronald A DePinho; Dean Bok; Donald J Zack
Tetracycline-inducible system for photoreceptor-specific gene expression.
Investigative ophthalmology & visual science 2000;41(13):4281-7.
2000: Kai-Yin Chau; Shuqi Chen; Donald J Zack; Santa Jeremy Ono
Functional domains of the cone-rod homeobox (CRX) transcription factor.
The Journal of biological chemistry 2000;275(47):37264-70.
2000: Kai-Yin Chau; Nikhil C Munshi; Andrea Keane-Myers; Kam-Wa Cheung-Chau; AK Tai; Guidalberto Manfioletti; C Kathleen Dorey; Dimitris Thanos; Donald J Zack; Santa Jeremy Ono
The architectural transcription factor high mobility group I(Y) participates in photoreceptor-specific gene expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(19):7317-24.
2000: Harry A Quigley; Stuart J McKinnon; Donald J Zack; Mary Ellen Pease; Lisa A Kerrigan-Baumrind; Danielle F Kerrigan; R S Mitchell
Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats.
Investigative ophthalmology & visual science 2000;41(11):3460-6.
2000: Haruhiko Yamada; Eri Yamada; N Kwak; Akira Ando; A Suzuki; Noriko Esumi; Donald J Zack; Peter A Campochiaro
Cell injury unmasks a latent proangiogenic phenotype in mice with increased expression of FGF2 in the retina.
Journal of cellular physiology 2000;185(1):135-42.
2000: kenneth mitton; Prabodh K Swain; Shiming Chen; Siqun Xu; Donald J Zack; Anand Swaroop
The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation.
The Journal of biological chemistry 2000;275(38):29794-9.
2000: Man-Seong Seo; Naoyuki Okamoto; MA Vinores; Stanley A Vinores; Sean F Hackett; Haruhiko Yamada; Eri Yamada; Nancy L Derevjanik; W LaRochelle; Donald J Zack; Peter A Campochiaro
Photoreceptor-specific expression of platelet-derived growth factor-B results in traction retinal detachment.
The American journal of pathology 2000;157(3):995-1005.
2000: Donald J Zack
Neurotrophic rescue of photoreceptors: are Müller cells the mediators of survival?
Neuron 2000;26(2):285-6.
2000: Karl Wahlin; Peter A Campochiaro; Donald J Zack; Ruben Adler
Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors.
Investigative ophthalmology & visual science 2000;41(3):927-36.
2000: Mary Ellen Pease; Stuart J McKinnon; Harry A Quigley; Lisa A Kerrigan-Baumrind; Donald J Zack
Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma.
Investigative ophthalmology & visual science 2000;41(3):764-74.
2000: Jeevan Mathura; N Jafari; J T Chang; Sean F Hackett; Karl Wahlin; Neil G Della; Naoyuki Okamoto; Donald J Zack; Peter A Campochiaro
Bone morphogenetic proteins-2 and -4: negative growth regulators in adult retinal pigmented epithelium.
Investigative ophthalmology & visual science 2000;41(2):592-600.
2000: Haruhiko Yamada; Eri Yamada; Akira Ando; Man-Seong Seo; Noriko Esumi; Naoyuki Okamoto; MA Vinores; W LaRochelle; Donald J Zack; Peter A Campochiaro
Platelet-derived growth factor-A-induced retinal gliosis protects against ischemic retinopathy.
The American journal of pathology 2000;156(2):477-87.
2000: S Chen; Donald J Zack
Cloning and characterization of retinal transcription factors, using target site-based methodology.
Methods in enzymology 2000;316():590-610.
1999: Donald J Zack; M Dean; Robert S Molday; Jeremy Nathans; T M Redmond; E M Stone; Anand Swaroop; David Valle; B H Weber
What can we learn about age-related macular degeneration from other retinal diseases?
Molecular vision 1999;5():30.
1999: Dale S Gregerson; J W Torseth; Scott W McPherson; Josh P Roberts; T Shinohara; Donald J Zack
Retinal expression of a neo-self antigen, beta-galactosidase, is not tolerogenic and creates a target for autoimmune uveoretinitis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):1073-80.
1999: Donald J Zack
Birth and death in the retina: more related than we thought?
Neuron 1999;23(3):411-2.
1999: MF Kniazeva; Michael Chiang; Garry R Cutting; Donald J Zack; Min Han; Kang Zhang
Clinical and genetic studies of an autosomal dominant cone-rod dystrophy with features of Stargardt disease.
Ophthalmic genetics 1999;20(2):71-81.
1999: Y Fei; Suraporn Matragoon; Sylvia B Smith; P A Overbeek; S Chen; Donald J Zack; Gregory I Liou
Functional dissection of the promoter of the interphotoreceptor retinoid-binding protein gene: the cone-rod-homeobox element is essential for photoreceptor-specific expression in vivo.
Journal of biochemistry 1999;125(6):1189-99.
1999: MF Kniazeva; Michael Chiang; B Morgan; A L Anduze; Donald J Zack; Min Han; Kang Zhang
A new locus for autosomal dominant stargardt-like disease maps to chromosome 4.
American journal of human genetics 1999;64(5):1394-9.
1999: David A R Bessant; Annette M Payne; kenneth mitton; Q L Wang; Prabodh K Swain; C Plant; Alan C Bird; Donald J Zack; Anand Swaroop; Shomi S Bhattacharya
A mutation in NRL is associated with autosomal dominant retinitis pigmentosa.
Nature genetics 1999;21(4):355-6.
1999: J T Chang; Noriko Esumi; K Moore; Yingying Li; S Zhang; C Chew; B Goodman; Amir Rattner; S Moody; Gail Stetten; Peter A Campochiaro; Donald J Zack
Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium.
Human molecular genetics 1999;8(4):575-83.
1999: Anand Swaroop; Q L Wang; W Wu; J Cook; CL Coats; Siqun Xu; Shiming Chen; Donald J Zack; Paul Sieving
Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: direct evidence for the involvement of CRX in the development of photoreceptor function.
Human molecular genetics 1999;8(2):299-305.
1999: H Ozaki; AY Yu; Neil G Della; K Ozaki; JD Luna; Haruhiko Yamada; Sean F Hackett; Naoyuki Okamoto; Donald J Zack; Gregg L Semenza; Peter A Campochiaro
Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression.
Investigative ophthalmology & visual science 1999;40(1):182-9.
1998: Samuel G Jacobson; Artur Vahe Cideciyan; Y Huang; D B Hanna; Carol L Freund-Taylor; Louisa M Affatigato; R E Carr; Donald J Zack; Edwin M Stone; Roderick R McInnes
Retinal degenerations with truncation mutations in the cone-rod homeobox (CRX) gene.
Investigative ophthalmology & visual science 1998;39(12):2417-26.
1998: DA Swanson; J T Chang; Peter A Campochiaro; Donald J Zack; David Valle
Mammalian orthologs of C. elegans unc-119 highly expressed in photoreceptors.
Investigative ophthalmology & visual science 1998;39(11):2085-94.
1998: H Ozaki; Naoyuki Okamoto; Sagrario Ortega; M Chang; K Ozaki; Srinivas R Sadda; MA Vinores; Nancy L Derevjanik; Donald J Zack; Claudio Basilico; Peter A Campochiaro
Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization.
The American journal of pathology 1998;153(3):757-65.
1998: Alberto Perez-Mediavilla; C Chew; Peter A Campochiaro; R W Nickells; V Notario; Donald J Zack; S Patricia Becerra
Sequence and expression analysis of bovine pigment epithelium-derived factor.
Biochimica et biophysica acta 1998;1398(2):203-14.
1998: Carol L Freund-Taylor; Q L Wang; S Chen; B L Muskat; C D Wiles; V C Sheffield; S G Jacobson; Roderick R McInnes; Donald J Zack; E M Stone
De novo mutations in the CRX homeobox gene associated with Leber congenital amaurosis.
Nature genetics 1998;18(4):311-2.
1998: Breandán N Kennedy; S Goldflam; M A Chang; Peter A Campochiaro; A A Davis; Donald J Zack; John W Crabb
Transcriptional regulation of cellular retinaldehyde-binding protein in the retinal pigment epithelium. A role for the photoreceptor consensus element.
The Journal of biological chemistry 1998;273(10):5591-8.
1998: Xiaojie Li; Shiming Chen; Q Wang; Donald J Zack; Solomon H Snyder; Jimo Borjigin
A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1876-81.
1998: T Tobe; Naoyuki Okamoto; MA Vinores; Nancy L Derevjanik; Stanley A Vinores; Donald J Zack; Peter A Campochiaro
Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors.
Investigative ophthalmology & visual science 1998;39(1):180-8.
1997: Prabodh K Swain; Shiming Chen; Q L Wang; Louisa M Affatigato; CL Coats; K D Brady; Gerald A Fishman; Samuel G Jacobson; Anand Swaroop; E Stone; Paul Sieving; Donald J Zack
Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration.
Neuron 1997;19(6):1329-36.
1997: Shiming Chen; Q L Wang; Z Nie; Hui Sun; G Lennon; Neal G Copeland; DJ Gilbert; Nancy A Jenkins; Donald J Zack
Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes.
Neuron 1997;19(5):1017-30.
1997: L A Kerrigan; Donald J Zack; Harry A Quigley; Sylvia B Smith; Mary Ellen Pease
TUNEL-positive ganglion cells in human primary open-angle glaucoma.
Archives of ophthalmology 1997;115(8):1031-5.
1997: J T Chang; S Milligan; Yongbo Li; C E Chew; J Wiggs; Neal G Copeland; Nancy A Jenkins; Peter A Campochiaro; D R Hyde; Donald J Zack
Mammalian homolog of Drosophila retinal degeneration B rescues the mutant fly phenotype.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(15):5881-90.
1997: Naoyuki Okamoto; T Tobe; Sean F Hackett; H Ozaki; MA Vinores; W LaRochelle; Donald J Zack; Peter A Campochiaro
Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization.
The American journal of pathology 1997;151(1):281-91.
1997: Henry D Jampel; X Chen; C Chue; Donald J Zack
Expression of carbonic anhydrase isozyme III in the ciliary processes and lens.
Investigative ophthalmology & visual science 1997;38(2):539-43.
1996: Robert W Nickells; Donald J Zack
Apoptosis in ocular disease: a molecular overview.
Ophthalmic genetics 1996;17(4):145-65.
1996: R Kumar; S Chen; D Scheurer; Q L Wang; Elia J Duh; C H Sung; Alnawaz Rehemtulla; Anand Swaroop; Ruben Adler; Donald J Zack
The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures.
The Journal of biological chemistry 1996;271(47):29612-8.
1996: S Chen; Donald J Zack
Ret 4, a positive acting rhodopsin regulatory element identified using a bovine retina in vitro transcription system.
The Journal of biological chemistry 1996;271(45):28549-57.
1996: C H Lee; N G Della; C E Chew; Donald J Zack
Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(21):6784-94.
1996: Donald J Zack; M Stempniak; A L Wong; Carol L Freund-Taylor; R H Weisbart
Mechanisms of cellular penetration and nuclear localization of an anti-double strand DNA autoantibody.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):2082-8.
1996: N G Della; Peter A Campochiaro; Donald J Zack
Localization of TIMP-3 mRNA expression to the retinal pigment epithelium.
Investigative ophthalmology & visual science 1996;37(9):1921-4.
1996: Peter A Campochiaro; M Chang; M Ohsato; Stanley A Vinores; Z Nie; Leonard M Hjelmeland; Alka Mansukhani; Claudio Basilico; Donald J Zack
Retinal degeneration in transgenic mice with photoreceptor-specific expression of a dominant-negative fibroblast growth factor receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(5):1679-88.
1996: Z Nie; S Chen; R Kumar; Donald J Zack
RER, an evolutionarily conserved sequence upstream of the rhodopsin gene, has enhancer activity.
The Journal of biological chemistry 1996;271(5):2667-75.
1996: Alnawaz Rehemtulla; R Warwar; R Kumar; X Ji; Donald J Zack; Anand Swaroop
The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):191-5.
1995: Donald J Zack; A L Wong; M Stempniak; R H Weisbart
Two kappa immunoglobulin light chains are secreted by an anti-DNA hybridoma: implications for isotypic exclusion.
Molecular immunology 1995;32(17-18):1345-53.
1995: Donald J Zack; M Stempniak; A L Wong; R H Weisbart
Localization of an Fc-binding reactivity to the constant region of human IgG4. Implications for the pathogenesis of rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):5057-63.
1995: Harry A Quigley; Robert W Nickells; L A Kerrigan; Mary Ellen Pease; D J Thibault; Donald J Zack
Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.
Investigative ophthalmology & visual science 1995;36(5):774-86.
1995: Donald J Zack; K Yamamoto; A L Wong; M Stempniak; C French; R H Weisbart
DNA mimics a self-protein that may be a target for some anti-DNA antibodies in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(4):1987-94.
1995: Robert W Nickells; C F Burgoyne; Harry A Quigley; Donald J Zack
Cloning and characterization of rod opsin cDNA from the Old World monkey, Macaca fascicularis.
Investigative ophthalmology & visual science 1995;36(1):72-82.
1994: Donald J Zack; A L Wong; R H Weisbart
Novel structural features of autoantibodies in murine lupus: a possible superantigen binding site?
Immunology and cell biology 1994;72(6):513-20.
1994: Peter Gouras; Hild Kjeldbye; Donald J Zack
Reporter gene expression in cones in transgenic mice carrying bovine rhodopsin promoter/lacZ transgenes.
Visual neuroscience 1994;11(6):1227-31.
1994: Peter Gouras; J Du; Hild Kjeldbye; S Yamamoto; Donald J Zack
Long-term photoreceptor transplants in dystrophic and normal mouse retina.
Investigative ophthalmology & visual science 1994;35(8):3145-53.
1994: M I Chiu; Donald J Zack; Y Wang; Jeremy Nathans
Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.
Genomics 1994;21(2):440-3.
1993: Donald J Zack
Ocular gene therapy. From fantasy to foreseeable reality.
Archives of ophthalmology 1993;111(11):1477-9.
1993: Donald J Zack
Of mice and men: what mice can teach us about human ophthalmic disease.
Archives of ophthalmology 1993;111(7):911-3.
1992: Y Wang; Jennifer P Macke; Shannath L Merbs; Donald J Zack; B Klaunberg; J Bennett; John D Gearhart; Jeremy Nathans
A locus control region adjacent to the human red and green visual pigment genes.
Neuron 1992;9(3):429-40.
1992: Peter Gouras; J Du; Hild Kjeldbye; S Yamamoto; Donald J Zack
Reconstruction of degenerate rd mouse retina by transplantation of transgenic photoreceptors.
Investigative ophthalmology & visual science 1992;33(9):2579-86.
1991: Peter Gouras; J Du; Hild Kjeldbye; R Kwun; R Lopez; Donald J Zack
Transplanted photoreceptors identified in dystrophic mouse retina by a transgenic reporter gene.
Investigative ophthalmology & visual science 1991;32(13):3167-74.
1991: Seung-Uon Shin; Ronald A DePinho; Donald J Zack; S Rudikoff; Matthew D Scharff
Instability of immunoglobulin genes in S107 cell line.
Somatic cell and molecular genetics 1991;17(3):259-76.
1991: Donald J Zack; J Bennett; Y Wang; C Davenport; B Klaunberg; John D Gearhart; Jeremy Nathans
Unusual topography of bovine rhodopsin promoter-lacZ fusion gene expression in transgenic mouse retinas.
Neuron 1991;6(2):187-99.
1987: A M Giusti; N C Chien; Donald J Zack; Seung-Uon Shin; Matthew D Scharff
Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2926-30.
1986: N Chien; A M Giusti; Donald J Zack; D French; Seung-Uon Shin; Betty Diamond; Matthew D Scharff
Effect of somatic mutation on antibody affinity and specificity.
The Mount Sinai journal of medicine, New York 1986;53(3):181-6.
1983: J L Teillaud; C Desaymard; A M Giusti; B Haseltine; R R Pollock; D E Yelton; Donald J Zack; Matthew D Scharff
Monoclonal antibodies reveal the structural basis of antibody diversity.
Science (New York, N.Y.) 1983;222(4625):721-6.
1981: Donald J Zack; S L Morrison; W D Cook; W Dackowski; Matthew D Scharff
Somatically generated mouse myeloma variants synthesizing IgA half-molecules.
The Journal of experimental medicine 1981;154(5):1554-69.
1980: W D Cook; S Rudikoff; A M Giusti; Donald J Zack; T Kelly; Matthew D Scharff
Antigen binding variants of the S107 mouse myeloma cell line.
Progress in clinical and biological research 1980;42():217-30.