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David Broide

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pejman Soroosh; Yan Fei Adams; David H Broide; Heonsik Choi; Taylor A Doherty; Wei Duan; Naseem Khorram; Amit Kumar Mehta; Zbigniew Mikulski; Peter Rosenthal; Michael Croft
Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance.
Kwang Je Baek; Jae Youn Cho; Victor Nizet; Peter Rosenthal; Laura E Crotty Alexander; David H Broide
Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model.
Véronique Schulten; Alessandro Sette; John Sidney; Fatima Ferreira; Rapheul Alam; David H Broide; Fatima Ferreira-Briza; Jason A Greenbaum; Howard M Grey; Michael Hauser; Ravi Kolla; Cecilia S Lindestam Arlehamn; Denise M McKinney; Carla Oseroff; Bjoern Peters
Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.

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2013: pejman Soroosh; Yan Fei Adams; David H Broide; Heonsik Choi; Taylor A Doherty; Wei Duan; Naseem Khorram; Amit Kumar Mehta; Zbigniew Mikulski; Peter Rosenthal; Michael Croft
Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance.
The Journal of experimental medicine 2013;210(4):775-88.
2013: Kwang Je Baek; Jae Youn Cho; Victor Nizet; Peter Rosenthal; Laura E Crotty Alexander; David H Broide
Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model.
Clinical immunology (Orlando, Fla.) 2013;147(1):27-37.
2013: Véronique Schulten; Alessandro Sette; John Sidney; Fatima Ferreira; Rapheul Alam; David H Broide; Fatima Ferreira-Briza; Jason A Greenbaum; Howard M Grey; Michael Hauser; Ravi Kolla; Cecilia S Lindestam Arlehamn; Denise M McKinney; Carla Oseroff; Bjoern Peters
Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(9):3459-64.
2012: Marina Miller; James L Mueller; Maho Niwa; Alexa Pham; Peter Rosenthal; Maho Suzukawa; Arvin B Tam; Jae Youn Cho; Taylor A Doherty; Hal M Hoffman; Naseem Khorram; David H Broide
ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(41):16648-53.
2012: Taylor A Doherty; Naseem Khorram; Hee-Kyoo Kim; Peter Rosenthal; Jinny E Chang; Michael Croft; David H Broide
STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria.
American journal of physiology. Lung cellular and molecular physiology 2012;303(7):L577-88.
2012: Carla Oseroff; Bjoern Peters; Federica Sallusto; Rafeul Alam; Tess M Brodie; David H Broide; Jason A Greenbaum; Howard Grey; Ravi Kolla; Denise M McKinney; John Sidney; Scott Southwood; Victoria Tripple; Randi Vita; Alessandro Sette
T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(4):1800-11.
2012: Carla Oseroff; Bjoern Peters; Anna Pomés; David H Broide; Jason Greenbaum; Howard Grey; Ravi Kolla; John Sidney; Victoria Tripple; Robert A Wood; Alessandro Sette
Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(2):679-88.
2012: Taylor A Doherty; Naseem Khorram; Marina Miller; Alexa Pham; Peter Rosenthal; Dean Sheppard; Kotaro Sugimoto; Jae Youn Cho; Michael Croft; David H Broide
Alternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(6):2622-9.
2011: Eitan Rubinstein; Ajit Varki; Seema S Aceves; James Chao; Jae Youn Cho; Marina Miller; Alexa Pham; Peter Rosenthal; David H Broide
Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis.
Journal of pediatric gastroenterology and nutrition 2011;53(4):409-16.
2011: Marina Miller; Alexa Pham; Joe Ramsdell; Jae Youn Cho; Paul J Friedman; David H Broide
Persistent airway inflammation and emphysema progression on CT scan in ex-smokers observed for 4 years.
Chest 2011;139(6):1380-7.
2011: Taylor A Doherty; pejman Soroosh; Naseem Khorram; Satoshi Fukuyama; Peter Rosenthal; Jae Youn Cho; Paula S Norris; Heonsik Choi; Stefanie Scheu; Klaus Pfeffer; Bruce L Zuraw; Carl Ware; David H Broide; Michael Croft
The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling.
Nature medicine 2011;17(5):596-603.
2011: Hye-Yung Yum; Jae Youn Cho; Marina Miller; David H Broide
Allergen-induced coexpression of bFGF and TGF-β1 by macrophages in a mouse model of airway remodeling: bFGF induces macrophage TGF-β1 expression in vitro.
International archives of allergy and immunology 2011;155(1):12-22.
2010: Seema S Aceves; Diana Chen; Robert O Newbury; Ranjan Dohil; John F Bastian; David H Broide
Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-β1, and increase esophageal smooth muscle contraction.
The Journal of allergy and clinical immunology 2010;126(6):1198-204.e4.
2010: Marina Miller; Alexa Pham; Jae Youn Cho; Peter Rosenthal; David H Broide
Adiponectin-deficient mice are protected against tobacco-induced inflammation and increased emphysema.
American journal of physiology. Lung cellular and molecular physiology 2010;299(6):L834-42.
2010: David H Broide
Allergic rhinitis: Pathophysiology.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2010;31(5):370-4.
2010: Sang Yeub Lee; Marina Miller; Jae Youn Cho; Dae Jin Song; Michael Karin; David H Broide
Inactivation of I kappaB-kinase-beta dependent genes in airway epithelium reduces tobacco smoke induced acute airway inflammation.
International immunopharmacology 2010;10(8):906-12.
2010: Suzan Pae; Jae Youn Cho; Shanna Dayan; Marina Miller; Alan Pemberton; David H Broide
Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9.
Immunogenetics 2010;62(8):499-506.
2010: Hiroyuki Takahashi; Hisanobu Ogata; Reiko Nishigaki; David H Broide; Michael Karin
Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation.
Cancer cell 2010;17(1):89-97.
2010: Jae Youn Cho; Dae Jae Song; Alexa Pham; Peter Rosenthal; Marina Miller; Shanna Dayan; Taylor A Doherty; Ajit Varki; David H Broide
Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13.
Respiratory research 2010;11():154.
2010: Dae Jin Song; Myung Goo Min; Marina Miller; Jae Youn Cho; Hye-Yung Yum; David H Broide
Toll-like receptor-9 agonist inhibits airway inflammation, remodeling and hyperreactivity in mice exposed to chronic environmental tobacco smoke and allergen.
International archives of allergy and immunology 2010;151(4):285-96.
2009: Dae Jin Song; Jae Youn Cho; Sang Yeub Lee; Marina Miller; Peter Rosenthal; pejman Soroosh; Michael Croft; Mai Zhang; Ajit Varki; David H Broide
Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):5333-41.
2009: Dae Jin Song; Myung Goo Min; Marina Miller; Jae Youn Cho; David H Broide
Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen.
American journal of physiology. Lung cellular and molecular physiology 2009;297(2):L380-7.
2009: Dae Jin Song; Jae Youn Cho; Marina Miller; Wendy Strangman; Mai Zhang; Ajit Varki; David H Broide
Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model.
Clinical immunology (Orlando, Fla.) 2009;131(1):157-69.
2009: David H Broide
Immunomodulation of allergic disease.
Annual review of medicine 2009;60():279-91.
2009: Marina Miller; Jae Youn Cho; Alexa Pham; Joe Ramsdell; David H Broide
Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):684-91.
2008: David H Broide
New perspectives on mechanisms underlying chronic allergic inflammation and asthma in 2007.
The Journal of allergy and clinical immunology 2008;122(3):475-80.
2008: Seema S Aceves; David H Broide
Airway fibrosis and angiogenesis due to eosinophil trafficking in chronic asthma.
Current molecular medicine 2008;8(5):350-8.
2008: David H Broide
Immunologic and inflammatory mechanisms that drive asthma progression to remodeling.
The Journal of allergy and clinical immunology 2008;121(3):560-70; quiz 571-2.
2007: Taylor Doherty; David H Broide
Cytokines and growth factors in airway remodeling in asthma.
Current opinion in immunology 2007;19(6):676-80.
2007: Tomoko Hayashi; Ji-Hun Mo; Xing Gong; Cyprian Rossetto; Angela Jang; Lucinda Beck; Gregory I Elliott; Irina Kufareva; Ruben Abagyan; David H Broide; Jongdae Lee; Eyal Raz
3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18619-24.
2007: Marina Miller; Joe Ramsdell; Paul J Friedman; Jae Youn Cho; Marian Renvall; David H Broide
Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema.
The Journal of allergy and clinical immunology 2007;120(5):1118-25.
2007: David H Broide
The pathophysiology of allergic rhinoconjunctivitis.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2007;28(4):398-403.
2007: Annie V Le; Jae Youn Cho; Marina Miller; Shauna McElwain; Kirsti Golgotiu; David H Broide
Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7310-6.
2007: Myung Goo Min; Dae Jin Song; Marina Miller; Jae Youn Cho; Shauna McElwain; Paul Ferguson; David H Broide
Coexposure to environmental tobacco smoke increases levels of allergen-induced airway remodeling in mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5321-8.
2007: Seema S Aceves; Robert O Newbury; Ranjan Dohil; John F Bastian; David H Broide
Esophageal remodeling in pediatric eosinophilic esophagitis.
The Journal of allergy and clinical immunology 2007;119(1):206-12.
2006: Dae Hyun Lim; Jae Youn Cho; Marina Miller; Kirsti McElwain; Shauna McElwain; David H Broide
Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice.
American journal of physiology. Lung cellular and molecular physiology 2006;291(2):L265-71.
2006: Jae Youn Cho; Marina Miller; Kirsti McElwain; Shauna McElwain; Jung Yeon Shim; Eyal Raz; David H Broide
Remodeling associated expression of matrix metalloproteinase 9 but not tissue inhibitor of metalloproteinase 1 in airway epithelium: modulation by immunostimulatory DNA.
The Journal of allergy and clinical immunology 2006;117(3):618-25.
2006: Sook Young Lee; Jae Youn Cho; Marina Miller; Kirsti McElwain; Shauna McElwain; Pragada Sriramarao; Eyal Raz; David H Broide
Immunostimulatory DNA inhibits allergen-induced peribronchial angiogenesis in mice.
The Journal of allergy and clinical immunology 2006;117(3):597-603.
2006: Annie V Le; David H Broide
Indoleamine-2,3-dioxygenase modulation of allergic immune responses.
Current allergy and asthma reports 2006;6(1):27-31.
2006: Marina Miller; Jae Youn Cho; Kirsti McElwain; Shauna McElwain; Jung Yeon Shim; Michael Manni; Ji Sun Baek; David H Broide
Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L162-9.
2005: David H Broide; Toby Lawrence; Taylor Doherty; Jae Youn Cho; Marina Miller; Kirsti McElwain; Shauna McElwain; Michael Karin
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(49):17723-8.
2005: Jae Youn Cho; Marina Miller; Kirsti McElwain; Shauna McElwain; David H Broide
Combination of corticosteroid therapy and allergen avoidance reverses allergen-induced airway remodeling in mice.
The Journal of allergy and clinical immunology 2005;116(5):1116-22.
2005: David H Broide
DNA vaccines: an evolving approach to the treatment of allergic disorders.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2005;26(3):195-8.
2005: Tomoko Hayashi; Xing Gong; Cyprian Rossetto; Carol Shen; Kenji Takabayashi; Vanessa Redecke; Hans L Spiegelberg; David H Broide; Eyal Raz
Induction and inhibition of the Th2 phenotype spread: implications for childhood asthma.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5864-73.
2005: David H Broide
Immunostimulatory sequences of DNA and conjugates in the treatment of allergic rhinitis.
Current allergy and asthma reports 2005;5(3):182-5.
2004: Cho Jae Youn; Marina Miller; Kwang Je Baek; Ji Won Han; Jyothi Nayar; Sook Young Lee; Kirsti McElwain; Shauna McElwain; Eyal Raz; David H Broide
Immunostimulatory DNA reverses established allergen-induced airway remodeling.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7556-64.
2004: Christoph J Binder; Karsten Hartvigsen; Mi-Kyung Chang; Marina Miller; David H Broide; Wulf Palinski; Linda K Curtiss; Maripat Corr; Joseph L Witztum
IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis.
The Journal of clinical investigation 2004;114(3):427-37.
2004: Tomoko Hayashi; Lucinda Beck; Cyprian Rossetto; Xing Gong; Osamu Takikawa; Kenji Takabayashi; David H Broide; Dennis A Carson; Eyal Raz
Inhibition of experimental asthma by indoleamine 2,3-dioxygenase.
The Journal of clinical investigation 2004;114(2):270-9.
2004: Jae Youn Cho; Marina Miller; Kwang Je Baek; Ji Won Han; Jyothi Nayar; Monica Rodriguez; Sook Young Lee; Kirsti McElwain; Shauna McElwain; Eyal Raz; David H Broide
Immunostimulatory DNA inhibits transforming growth factor-beta expression and airway remodeling.
American journal of respiratory cell and molecular biology 2004;30(5):651-61.
2004: Vanessa Redecke; Hans Häcker; Sandip K Datta; Agnes Fermin; PAULA PITHA-ROWE; David H Broide; Eyal Raz
Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2739-43.
2004: Jae Youn Cho; Marina Miller; Kwang Je Baek; Ji Won Han; Jyothi Nayar; Sook Young Lee; Kirsti McElwain; Shauna McElwain; Stephanie Friedman; David H Broide
Inhibition of airway remodeling in IL-5-deficient mice.
The Journal of clinical investigation 2004;113(4):551-60.
2003: Reid K Ikeda; Marina Miller; Jyothi Nayar; Linda Walker; Jae Youn Cho; Kirsti McElwain; Shauna McElwain; Eyal Raz; David H Broide
Accumulation of peribronchial mast cells in a mouse model of ovalbumin allergen induced chronic airway inflammation: modulation by immunostimulatory DNA sequences.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4860-7.
2003: Reid K Ikeda; Jyothi Nayar; Jae Youn Cho; Marina Miller; Monica Rodriguez; Eyal Raz; David H Broide
Resolution of airway inflammation following ovalbumin inhalation: comparison of ISS DNA and corticosteroids.
American journal of respiratory cell and molecular biology 2003;28(6):655-63.
2003: Lyudmila Sikora; Ann-Cathrine Johansson; Savita P Rao; Greg K Hughes; David H Broide; Pragada Sriramarao
A murine model to study leukocyte rolling and intravascular trafficking in lung microvessels.
The American journal of pathology 2003;162(6):2019-28.
2003: Hal M Hoffman; Simon G Gregory; James L Mueller; Mark Tresierras; David H Broide; Alan A Wanderer; Richard D Kolodner
Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P.
Human genetics 2003;112(2):209-16.
2003: Sophia K Khaldoyanidi; Lyudmila Sikora; David H Broide; Marc E Rothenberg; Pragada Sriramarao
Constitutive overexpression of IL-5 induces extramedullary hematopoiesis in the spleen.
Blood 2003;101(3):863-8.
2002: Marina Miller; Jae Youn Cho; Kwang Je Baek; Diego Castaneda; Jyothi Nayar; Monica Rodriguez; Mark Roman; Eyal Raz; David H Broide
Plasmid DNA encoding the respiratory syncytial virus G protein protects against RSV-induced airway hyperresponsiveness.
Vaccine 2002;20(23-24):3023-33.
2002: David H Broide
Fast flowing eosinophils: signals for stopping and stepping out of blood vessels.
American journal of respiratory cell and molecular biology 2002;26(6):637-40.
2002: David H Broide; Marina Miller; Diego Castaneda; Jyothi Nayar; Jae Youn Cho; Mark Roman; Lesley G Ellies; Pragada Sriramarao
Core 2 oligosaccharides mediate eosinophil and neutrophil peritoneal but not lung recruitment.
American journal of physiology. Lung cellular and molecular physiology 2002;282(2):L259-66.
2001: David H Broide; G Stachnick; Diego Castaneda; Jyothi Nayar; Marina Miller; J Cho; M Rodriquez; Mark Roman; Eyal Raz
Immunostimulatory DNA mediates inhibition of eosinophilic inflammation and airway hyperreactivity independent of natural killer cells in vivo.
The Journal of allergy and clinical immunology 2001;108(5):759-63.
2001: Jae Youn Cho; Marina Miller; Kwang Je Baek; Diego Castaneda; Jyothi Nayar; Mark Roman; Eyal Raz; David H Broide
Immunostimulatory DNA sequences inhibit respiratory syncytial viral load, airway inflammation, and mucus secretion.
The Journal of allergy and clinical immunology 2001;108(5):697-702.
2001: Hal M Hoffman; James L Mueller; David H Broide; Alan A Wanderer; Richard D Kolodner
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome.
Nature genetics 2001;29(3):301-5.
2001: Hal M Hoffman; Alan A Wanderer; David H Broide
Familial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic fever.
The Journal of allergy and clinical immunology 2001;108(4):615-20.
2001: Marina Miller; K L Sung; W A Muller; Jae Youn Cho; Mark Roman; Diego Castaneda; Jyothi Nayar; T Condon; J Kim; Pragada Sriramarao; David H Broide
Eosinophil tissue recruitment to sites of allergic inflammation in the lung is platelet endothelial cell adhesion molecule independent.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2292-7.
2001: David H Broide; G Stachnick; Diego Castaneda; Jyothi Nayar; Marina Miller; Jae Youn Cho; Mark Roman; Jose Zubeldia; T Hayashi; Eyal Raz; T Hyashi
Systemic administration of immunostimulatory DNA sequences mediates reversible inhibition of Th2 responses in a mouse model of asthma.
Journal of clinical immunology 2001;21(3):175-82.
2001: M Cecilia Berin; Lars Eckmann; David H Broide; Martin F Kagnoff
Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts.
American journal of respiratory cell and molecular biology 2001;24(4):382-9.
2001: David H Broide; G Stachnick; Diego Castaneda; Jyothi Nayar; Pragada Sriramarao
Inhibition of eosinophilic inflammation in allergen-challenged TNF receptor p55/p75--and TNF receptor p55-deficient mice.
American journal of respiratory cell and molecular biology 2001;24(3):304-11.
2001: David H Broide; Pragada Sriramarao
Eosinophil trafficking to sites of allergic inflammation.
Immunological reviews 2001;179():163-72.
2001: Anthony A Horner; John Henry Van Uden; Jose Zubeldia; David H Broide; Eyal Raz
DNA-based immunotherapeutics for the treatment of allergic disease.
Immunological reviews 2001;179():102-18.
2000: K P Sung; L Yang; J Kim; D Ko; G Stachnick; Diego Castaneda; Jyothi Nayar; David H Broide
Eotaxin induces a sustained reduction in the functional adhesive state of very late antigen 4 for the connecting segment 1 region of fibronectin.
The Journal of allergy and clinical immunology 2000;106(5):933-40.
2000: Hal M Hoffman; Fred A Wright; David H Broide; Alan A Wanderer; Richard D Kolodner
Identification of a locus on chromosome 1q44 for familial cold urticaria.
American journal of human genetics 2000;66(5):1693-8.
2000: Pragada Sriramarao; Richard G DiScipio; R R Cobb; M Cybulsky; G Stachnick; Diego Castaneda; M Elices; David H Broide
VCAM-1 is more effective than MAdCAM-1 in supporting eosinophil rolling under conditions of shear flow.
Blood 2000;95(2):592-601.
2000: David H Broide; Jae Youn Cho; Marina Miller; Jyothi Nayar; G Stachnick; Diego Castaneda; Mark Roman; Eyal Raz
Modulation of asthmatic response by immunostimulatory DNA sequences.
Springer seminars in immunopathology 2000;22(1-2):117-24.
2000: David H Broide; K Campbell; T Gifford; Pragada Sriramarao
Inhibition of eosinophilic inflammation in allergen-challenged, IL-1 receptor type 1-deficient mice is associated with reduced eosinophil rolling and adhesion on vascular endothelium.
Blood 2000;95(1):263-9.
1999: David H Broide; H Hoffman; Pragada Sriramarao
Genes that regulate eosinophilic inflammation.
American journal of human genetics 1999;65(2):302-7.
1999: David H Broide; Eyal Raz
DNA-Based immunization for asthma.
International archives of allergy and immunology 1999;118(2-4):453-6.
1999: Richard G DiScipio; PJ Daffern; MA Jagels; David H Broide; Pragada Sriramarao
A comparison of C3a and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1127-36.
1998: David H Broide; J Schwarze; Helen Tighe; T Gifford; MD Nguyen; S Malek; John Henry Van Uden; Elena Martin-Orozco; E W Gelfand; Eyal Raz
Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):7054-62.
1998: J S Goodman; John Henry Van Uden; H Kobayashi; David H Broide; Eyal Raz
DNA immunotherapeutics: new potential treatment modalities for allergic disease.
International archives of allergy and immunology 1998;116(3):177-87.
1998: David H Broide; D Humber; S Sullivan; Pragada Sriramarao
Inhibition of eosinophil rolling and recruitment in P-selectin- and intracellular adhesion molecule-1-deficient mice.
Blood 1998;91(8):2847-56.
1998: David H Broide; S Sullivan; T Gifford; Pragada Sriramarao
Inhibition of pulmonary eosinophilia in P-selectin- and ICAM-1-deficient mice.
American journal of respiratory cell and molecular biology 1998;18(2):218-25.
1997: K L Sung; Y Li; M Elices; J Gang; Pragada Sriramarao; David H Broide
Granulocyte-macrophage colony-stimulating factor regulates the functional adhesive state of very late antigen-4 expressed by eosinophils.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):919-27.
1996: Pragada Sriramarao; C R Norton; P Borgstrom; Richard G DiScipio; B A Wolitzky; David H Broide
E-selectin preferentially supports neutrophil but not eosinophil rolling under conditions of flow in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4672-80.
1996: Pragada Sriramarao; David H Broide
Differential regulation of eosinophil adhesion under conditions of flow in vivo.
Annals of the New York Academy of Sciences 1996;796():218-25.
1996: S Sullivan; David H Broide
Compartmentalization of eosinophil granulocyte-macrophage colony-stimulating factor expression in patients with asthma.
The Journal of allergy and clinical immunology 1996;97(4):966-76.
1996: Pragada Sriramarao; W Anderson; B A Wolitzky; David H Broide
Mouse bone marrow-derived mast cells roll on P-selectin under conditions of flow in vivo.
Laboratory investigation; a journal of technical methods and pathology 1996;74(3):634-43.
1996: W H Anderson; T M Davidson; David H Broide
Mast cell TNF mRNA expression in nasal mucosa demonstrated by in situ hybridization: a comparison of mast cell detection methods.
Journal of immunological methods 1996;189(2):145-55.
1996: M S Weinberger; T M Davidson; David H Broide
Differential expression of vascular cell adhesion molecule mRNA and protein in nasal mucosa in response to IL-1 or tumor necrosis factor.
The Journal of allergy and clinical immunology 1996;97(2):662-71.
1995: P Ferguson; David H Broide
Environmental and bronchoalveolar lavage Dermatophagoides pteronyssinus antigen levels in atopic asthmatics.
American journal of respiratory and critical care medicine 1995;151(1):71-4.
1995: David H Broide
Alpha 4 integrin-induced cytokine production and eosinophil function.
Springer seminars in immunopathology 1995;16(4):405-15.
1994: Pragada Sriramarao; Ulrich H von Andrian; Eugene C Butcher; MA Bourdon; David H Broide
L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):4238-46.
1992: David H Broide; M M Paine; Gary S Firestein
Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics.
The Journal of clinical investigation 1992;90(4):1414-24.
1992: David H Broide; M Lotz; A J Cuomo; D A Coburn; E C Federman; Stephen I Wasserman
Cytokines in symptomatic asthma airways.
The Journal of allergy and clinical immunology 1992;89(5):958-67.
1991: Stephen I Wasserman; David H Broide; D L Marquardt
Cetirizine therapy for seasonal allergic rhinitis: alternative dosage schedules.
Clinical therapeutics 1991;13(6):707-13.
1991: David H Broide; G J Gleich; A J Cuomo; D A Coburn; E C Federman; L B Schwartz; Stephen I Wasserman
Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway.
The Journal of allergy and clinical immunology 1991;88(4):637-48.
1991: David H Broide; Gary S Firestein
Endobronchial allergen challenge in asthma. Demonstration of cellular source of granulocyte macrophage colony-stimulating factor by in situ hybridization.
The Journal of clinical investigation 1991;88(3):1048-53.
1990: David H Broide; C M Smith; Stephen I Wasserman
Mast cells and pulmonary fibrosis. Identification of a histamine releasing factor in bronchoalveolar lavage fluid.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1838-44.
1990: David H Broide; S Eisman; J W Ramsdell; P Ferguson; L B Schwartz; Stephen I Wasserman
Airway levels of mast cell-derived mediators in exercise-induced asthma.
The American review of respiratory disease 1990;141(3):563-8.
1989: David H Broide; Stephen I Wasserman; J Alvaro-Gracia; Nathan J Zvaifler; Gary S Firestein
Transforming growth factor-beta 1 selectively inhibits IL-3-dependent mast cell proliferation without affecting mast cell function or differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(5):1591-7.
1989: Stephen I Wasserman; D L Marquardt; David H Broide; L Walker; K Barrett
Characterization, activation, and functional importance of mucosal mast cells.
Progress in clinical and biological research 1989;297():155-61; discussion 161.
1988: David H Broide; D D Metcalfe; Stephen I Wasserman
Functional and biochemical characterization of rat bone marrow derived mast cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(12):4298-305.
1988: Gary S Firestein; W D Xu; K Townsend; David H Broide; J Alvaro-Gracia; A Glasebrook; Nathan J Zvaifler
Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis.
The Journal of experimental medicine 1988;168(5):1573-86.