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Mark Zak

Research Profile

Chemicals & Drugs

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X Ray Crystallography

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Publications

TOP 3
Kyriacos C Nicolaou; Mark Zak; Shai Rahimipour; Anthony A Estrada; Sang Hyup Lee; Aurora O'Brate; Paraskevi Giannakakou; M Reza Ghadiri
Discovery of a biologically active thiostrepton fragment.
Kyriacos C Nicolaou; Mark Zak; Brian S Safina; Anthony A Estrada; Sang Hyup Lee; Marta Nevalainen
Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis.
Kyriacos C Nicolaou; Brian S Safina; Mark Zak; Sang Hyup Lee; Marta Nevalainen; Marco Bella; Anthony A Estrada; Christian Funke; Frédéric J Zécri; Stephan Bulat
Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks.

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All Publications

2005: Kyriacos C Nicolaou; Mark Zak; Shai Rahimipour; Anthony A Estrada; Sang Hyup Lee; Aurora O'Brate; Paraskevi Giannakakou; M Reza Ghadiri
Discovery of a biologically active thiostrepton fragment.
Journal of the American Chemical Society 2005;127(43):15042-4.
2005: Kyriacos C Nicolaou; Mark Zak; Brian S Safina; Anthony A Estrada; Sang Hyup Lee; Marta Nevalainen
Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis.
Journal of the American Chemical Society 2005;127(31):11176-83.
2005: Kyriacos C Nicolaou; Brian S Safina; Mark Zak; Sang Hyup Lee; Marta Nevalainen; Marco Bella; Anthony A Estrada; Christian Funke; Frédéric J Zécri; Stephan Bulat
Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks.
Journal of the American Chemical Society 2005;127(31):11159-75.
2005: Kyriacos C Nicolaou; Sang Hyup Lee; Anthony A Estrada; Mark Zak
Construction of substituted N-hydroxyindoles: synthesis of a nocathiacin I model system.
Angewandte Chemie (International ed. in English) 2005;44(24):3736-40.
2005: Kyriacos C Nicolaou; Anthony A Estrada; Mark Zak; Sang Hyup Lee; Brian S Safina
A mild and selective method for the hydrolysis of esters with trimethyltin hydroxide.
Angewandte Chemie (International ed. in English) 2005;44(9):1378-82.
2004: Kyriacos C Nicolaou; Brian S Safina; Mark Zak; Anthony A Estrada; Sang Hyup Lee
Total synthesis of thiostrepton, part 1: construction of the dehydropiperidine/thiazoline-containing macrocycle.
Angewandte Chemie (International ed. in English) 2004;43(38):5087-92.
2004: Kyriacos C Nicolaou; Mark Zak; Brian S Safina; Sang Hyup Lee; Anthony A Estrada
Total synthesis of thiostrepton, part 2: construction of the quinaldic acid macrocycle and final stages of the synthesis.
Angewandte Chemie (International ed. in English) 2004;43(38):5092-7.
2003: Kyriacos C Nicolaou; Marta Nevalainen; Mark Zak; Stephan Bulat; Marco Bella; Brian S Safina
Synthetic studies on thiostrepton: construction of thiostrepton analogues with the thiazoline-containing macrocycle.
Angewandte Chemie (International ed. in English) 2003;42(29):3418-24.
2002: Kyriacos C Nicolaou; Marta Nevalainen; Brian S Safina; Mark Zak; Stephan Bulat
A biomimetically inspired synthesis of the dehydropiperidine domain of thiostrepton.
Angewandte Chemie (International ed. in English) 2002;41(11):1941-5.
2002: Kyriacos C Nicolaou; Brian S Safina; Christian Funke; Mark Zak; Frédéric J Zécri
Stereocontrolled synthesis of the quinaldic acid macrocyclic system of thiostrepton.
Angewandte Chemie (International ed. in English) 2002;41(11):1937-40.