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Franck Broly

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Phenomena

Single-Stranded Conformational Polymorphism

Physiology

Procedures

Genes & Molecular Sequences

Alleles

Concepts & Ideas

Living Beings

European Continental Ancestry Group

Geographic Areas

France

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Publications

TOP 3
de Beaumais Tiphaine Adam; Fakhoury May; Pigneur Benedicte; Viola Sheila; Medard Yves; Broly Franck; Jacqz-Aigrain Evelyne
Characterization of a novel TPMT mutation associated with azathioprine-induced myelosuppression.
Standaert-Vitse Annie; Sendid Boualem; Joossens Marie; François Nadine; Vandewalle-El Khoury Peggy; Branche Julien; Van Kruiningen Herbert; Jouault Thierry; Rutgeerts Paul; Gower-Rousseau Corinne; Libersa Christian; Neut Christel; Broly Franck; Chamaillard Mathias; Vermeire Séverine; Poulain Daniel; Colombel Jean-Frédéric
Candida albicans colonization and ASCA in familial Crohn's disease.
Bezier Maud; Reguiai Ziad; Vitry Fabien; Broly Franck; Bernard Philippe
Thiopurine S-methyltransferase genotypic analysis in autoimmune bullous diseases.

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All Publications

2009: de Beaumais Tiphaine Adam; Fakhoury May; Pigneur Benedicte; Viola Sheila; Medard Yves; Broly Franck; Jacqz-Aigrain Evelyne
Characterization of a novel TPMT mutation associated with azathioprine-induced myelosuppression.
British journal of clinical pharmacology 2009;68(5):770-2.
2009: Standaert-Vitse Annie; Sendid Boualem; Joossens Marie; François Nadine; Vandewalle-El Khoury Peggy; Branche Julien; Van Kruiningen Herbert; Jouault Thierry; Rutgeerts Paul; Gower-Rousseau Corinne; Libersa Christian; Neut Christel; Broly Franck; Chamaillard Mathias; Vermeire Séverine; Poulain Daniel; Colombel Jean-Frédéric
Candida albicans colonization and ASCA in familial Crohn's disease.
The American journal of gastroenterology 2009;104(7):1745-53.
2008: Bezier Maud; Reguiai Ziad; Vitry Fabien; Broly Franck; Bernard Philippe
Thiopurine S-methyltransferase genotypic analysis in autoimmune bullous diseases.
European journal of dermatology : EJD 2008;18(5):512-7.
2008: Garat A; Cauffiez C; Renault N; Lo-Guidice J M; Allorge D; Chevalier D; Houdret N; Chavatte P; Loriot M A; Gala J L; Broly F
Characterisation of novel defective thiopurine S-methyltransferase allelic variants.
Biochemical pharmacology 2008;76(3):404-15.
2007: Tournel G; Cauffiez C; Leclerc J; Billaut-Laden I; Allorge D; Chevalier D; Migot-Nabias F; Kenani A; Broly F; Lo-Guidice J -M
CYP2F1 genetic polymorphism: identification of interethnic variations.
Xenobiotica; the fate of foreign compounds in biological systems 2007;37(12):1433-8.
2007: Allorge D; Beaune P-H; Becquemont L; Bessard G; Bezieau S; Boisdron-Celle M; Boyer J-C; Broly F; Dhaneens C-M; Fonrose X; Gagnieu M-C; Gamelin E; Gozé C; Jacqz-Aigrain E; Loric S; Loriot M-A; Marquet P; Morel A; Namour B; Paintaud G; Peoc'h K; Picard N; Watier H; Verstuyft C
[Molecular pharmacogenetics in hospital laboratories in France: current data and future prospects]
Annales pharmaceutiques françaises 2007;65(6):371-81.
2007: Tournel Gilles; Cauffiez Christelle; Billaut-Laden Ingrid; Allorge Delphine; Chevalier Dany; Bonnifet Fabien; Mensier Eric; Lafitte Jean-Jacques; Lhermitte Michel; Broly Franck; Lo-Guidice Jean-Marc
Molecular analysis of the CYP2F1 gene: identification of a frequent non-functional allelic variant.
Mutation research 2007;617(1-2):79-89.
2006: Quaranta S; Chevalier D; Allorge D; Lo-Guidice J M; Migot-Nabias F; Kenani A; Imbenotte M; Broly F; Lacarelle B; Lhermitte M
Ethnic differences in the distribution of CYP3A5 gene polymorphisms.
Xenobiotica; the fate of foreign compounds in biological systems 2006;36(12):1191-200.
2006: Lhermitte M; Allorge D; Broly F
[Therapeutic failure: importance of genes?]
Annales pharmaceutiques françaises 2006;64(6):406-15.
2006: Bonnet-Brilhault Frédérique; Broly Frank; Blanc Romuald; Furet Yves; Barthélémy Catherine; Paintaud Gilles
An ADHD 6-year-old child ultrarapid metabolizer for CYP2D6.
Journal of clinical psychopharmacology 2006;26(4):442-4.
2006: Billaut-Laden Ingrid; Allorge Delphine; Crunelle-Thibaut Aurélie; Rat Emmanuel; Cauffiez Christelle; Chevalier Dany; Houdret Nicole; Lo-Guidice Jean-Marc; Broly Franck
Evidence for a functional genetic polymorphism of the human thiosulfate sulfurtransferase (Rhodanese), a cyanide and H2S detoxification enzyme.
Toxicology 2006;225(1):1-11.
2006: Billaut-Laden Ingrid; Rat Emmanuel; Allorge Delphine; Crunelle-Thibaut Aurélie; Cauffiez Christelle; Chevalier Dany; Lo-Guidice Jean-Marc; Broly Franck
Evidence for a functional genetic polymorphism of the human mercaptopyruvate sulfurtransferase (MPST), a cyanide detoxification enzyme.
Toxicology letters 2006;165(2):101-11.
2006: Duparc Adeline; Staumont-Sallé Delphine; Broly Franck; Piette Frédéric; Delaporte Emmanuel
[Treatment of chronic lupus erythematosus with sulfasalazine in 18 patients: reappraisal]
Presse médicale (Paris, France : 1983) 2006;35(7-8):1138-42.
2006: Quaranta Sylvie; Chevalier Dany; Bourgarel-Rey Véronique; Allorge Delphine; Solas Caroline; Lo-Guidice Jean-Marc; Sampol-Manos Emmanuelle; Vacher-Coponat Henri; Moal Valérie; Broly Franck; Lhermitte Michel; Lacarelle Bruno
Identification by single-strand conformational polymorphism analysis of known and new mutations of the CYP3A5 gene in a French population.
Toxicology letters 2006;164(2):177-84.
2006: Rat Emmanuel; Billaut-Laden Ingrid; Allorge Delphine; Lo-Guidice Jean-Marc; Tellier Marie; Cauffiez Christelle; Jonckheere Nicolas; van Seuningen Isabelle; Lhermitte Michel; Romano Antonio; Guéant Jean-Louis; Broly Franck
Evidence for a functional genetic polymorphism of the human retinoic acid-metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida.
Birth defects research. Part A, Clinical and molecular teratology 2006;76(6):491-8.
2006: Lhermitte Michel; Allorge Delphine; Broly Franck
[Xenobiotic-metabolizing polymorphic enzymes. An opportunity for individualized drug treatment]
Bulletin de l'Académie nationale de médecine 2006;190(1):55-69; discussion 69-73.
2005: Cauffiez C; Pottier N; Tournel G; Lo-Guidice J-M; Allorge D; Chevalier D; Migot-Nabias F; Kenani A; Broly F
CYP2A13 genetic polymorphism in French Caucasian, Gabonese and Tunisian populations.
Xenobiotica; the fate of foreign compounds in biological systems 2005;35(7):661-9.
2005: Allorge Delphine; Bréant Didier; Harlow Jacky; Chowdry Joey; Lo-Guidice Jean-Marc; Chevalier Dany; Cauffiez Christelle; Lhermitte Michel; Blaney Frank E; Tucker Geoffrey T; Broly Franck; Ellis S Wynne
Functional analysis of CYP2D6.31 variant: homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution.
Proteins 2005;59(2):339-46.
2005: Allorge D; Hamdan R; Broly F; Libersa C; Colombel J-F
ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression.
Gut 2005;54(4):565.
2005: Hamdan-Khalil Rima; Gala Jean-Luc; Allorge Delphine; Lo-Guidice Jean-Marc; Horsmans Yves; Houdret Nicole; Broly Franck
Identification and functional analysis of two rare allelic variants of the thiopurine S-methyltransferase gene, TPMT*16 and TPMT*19.
Biochemical pharmacology 2005;69(3):525-9.
2004: Cauffiez Christelle; Klinzig Florian; Rat Emmanuel; Tournel Gilles; Allorge Delphine; Chevalier Dany; Pottier Nicolas; Lovecchio Tonio; Colombel Jean-Frédéric; Lhermitte Michel; Lo-Guidice Jean-Marc; Broly Franck
Human CYP4F12 genetic polymorphism: identification and functional characterization of seven variant allozymes.
Biochemical pharmacology 2004;68(12):2417-25.
2004: Vandel P; Haffen E; Nezelof S; Broly F; Kantelip J P; Sechter D
Clomipramine, fluoxetine and CYP2D6 metabolic capacity in depressed patients.
Human psychopharmacology 2004;19(5):293-8.
2004: Cauffiez Christelle; Klinzig Florian; Rat Emmanuel; Tournel Gilles; Allorge Delphine; Chevalier Dany; Lovecchio Tonio; Pottier Nicolas; Colombel Jean-Frédéric; Lhermitte Michel; D'Halluin Jean-Claude; Broly Franck; Lo-Guidice Jean-Marc
Functional characterization of genetic polymorphisms identified in the human cytochrome P450 4F12 (CYP4F12) promoter region.
Biochemical pharmacology 2004;67(12):2231-8.
2004: Eap Chin B; Bender Stefan; Jaquenoud Sirot E; Cucchia Gianni; Jonzier-Perey Michèle; Baumann Pierre; Allorge Delphine; Broly Franck
Nonresponse to clozapine and ultrarapid CYP1A2 activity: clinical data and analysis of CYP1A2 gene.
Journal of clinical psychopharmacology 2004;24(2):214-9.
2004: Cauffiez Christelle; Lo-Guidice Jean-Marc; Quaranta Sylvie; Allorge Delphine; Chevalier Dany; Cenée Sylvie; Hamdan Rima; Lhermitte Michel; Lafitte Jean-Jacques; Libersa Christian; Colombel Jean-Frédéric; Stücker Isabelle; Broly Franck
Genetic polymorphism of the human cytochrome CYP2A13 in a French population: implication in lung cancer susceptibility.
Biochemical and biophysical research communications 2004;317(2):662-9.
2004: Cauffiez Christelle; Lo-Guidice Jean-Marc; Chevalier Dany; Allorge Delphine; Hamdan Rima; Lhermitte Michel; Lafitte Jean-Jacques; Colombel Jean-Frédéric; Libersa Christian; Broly Franck
First report of a genetic polymorphism of the cytochrome P450 3A43 (CYP3A43) gene: identification of a loss-of-function variant.
Human mutation 2004;23(1):101.
2003: Charlier Corinne; Broly Franck; Lhermitte Michel; Pinto Emmanuel; Ansseau Marc; Plomteux Guy
Polymorphisms in the CYP 2D6 gene: association with plasma concentrations of fluoxetine and paroxetine.
Therapeutic drug monitoring 2003;25(6):738-42.
2003: Brocvielle H; Muret P; Goydadin A-C; Boone P; Broly F; Kantelip J-P; Humbert P
N-acetyltransferase 2 acetylation polymorphism: prevalence of slow acetylators does not differ between atopic dermatitis patients and healthy subjects.
Skin pharmacology and applied skin physiology 2003;16(6):386-92.
2003: Hamdan-Khalil Rima; Allorge Delphine; Lo-Guidice Jean-Marc; Cauffiez Christelle; Chevalier Dany; Spire Catherine; Houdret Nicole; Libersa Christian; Lhermitte Michel; Colombel Jean-Frédéric; Gala Jean-Luc; Broly Franck
In vitro characterization of four novel non-functional variants of the thiopurine S-methyltransferase.
Biochemical and biophysical research communications 2003;309(4):1005-10.
2003: Allorge Delphine; Chevalier Dany; Lo-Guidice Jean-Marc; Cauffiez Christelle; Suard Françoise; Baumann Pierre; Eap Chin B; Broly Franck
Identification of a novel splice-site mutation in the CYP1A2 gene.
British journal of clinical pharmacology 2003;56(3):341-4.
2002: Chevalier Dany; Allorge Delphine; Lo-Guidice Jean-Marc; Cauffiez Christelle; Lepetit Caroline; Migot-Nabias Florence; Kenani Abderaouf; Lhermitte Michel; Broly Franck
Sequence analysis, frequency and ethnic distribution of VNTR polymorphism in the 5'-untranslated region of the human prostacyclin synthase gene (CYP8A1).
Prostaglandins & other lipid mediators 2002;70(1-2):31-7.
2002: Lo-Guidice Jean-Marc; Allorge Delphine; Cauffiez Christelle; Chevalier Dany; Lafitte Jean-Jacques; Lhermitte Michel; Broly Franck
Genetic polymorphism of the human cytochrome P450 CYP4B1: evidence for a non-functional allelic variant.
Pharmacogenetics 2002;12(5):367-74.
2002: Becquemont Laurent; Chazouilleres Olivier; Serfaty Lawrence; Poirier Jean Marie; Broly Franck; Jaillon Patrice; Poupon Raoul; Funck-Brentano Christian
Effect of interferon alpha-ribavirin bitherapy on cytochrome P450 1A2 and 2D6 and N-acetyltransferase-2 activities in patients with chronic active hepatitis C.
Clinical pharmacology and therapeutics 2002;71(6):488-95.
2001: Allorge D; Harlow J; Boulet O; Hayhurst G P; Chowdry J; Roth E; Crewe K; Lo-Guidice J M; Lhermitte M; Broly F; Tucker G T; Ellis S W
In-vitro analysis of the contribution of CYP2D6.35 to ultra-rapid metabolism.
Pharmacogenetics 2001;11(8):739-41.
2001: Chevalier D; Cauffiez C; Allorge D; Lo-Guidice J M; Lhermitte M; Lafitte J J; Broly F
Five novel natural allelic variants-951A>C, 1042G>A (D348N), 1156A>T (I386F), 1217G>A (C406Y) and 1291C>T (C431Y)-of the human CYP1A2 gene in a French Caucasian population.
Human mutation 2001;17(4):355-6.
2001: Chevalier D; Allorge D; Lo-Guidice J M; Cauffiez C; Lhermitte M; Lafitte J J; Broly F
Detection of known and two novel (M331I and R464S) missense mutations in the human CYP1A1 gene in a French Caucasian population.
Human mutation 2001;17(4):355.
2001: Chevalier D; Cauffiez C; Bernard C; Lo-Guidice J M; Allorge D; Fazio F; Ferrari N; Libersa C; Lhermitte M; D'Halluin J C; Broly F
Characterization of new mutations in the coding sequence and 5'-untranslated region of the human prostacylcin synthase gene (CYP8A1).
Human genetics 2001;108(2):148-55.
2001: Chevalier D; Lo-Guidice J M; Sergent E; Allorge D; Debuysère H; Ferrari N; Libersa C; Lhermitte M; Broly F
Identification of genetic variants in the human thromboxane synthase gene (CYP5A1).
Mutation research 2001;432(3-4):61-7.
2000: Belmahdi F; Chevalier D; Lo-Guidice J M; Allorge D; Cauffiez C; Lafitte J J; Broly F
Identification of 6 new polymorphisms, g.11177G>A, g.14622C>T (R49C), g.17540T>C, g.17639T>C, g.30929T>C, g.31074G>A (R454Q), in the human microsomal epoxide hydrolase gene (EPHX1) in a French population.
Human mutation 2000;16(5):450.
2000: Lo-Guidice J M; Allorge D; Chevalier D; Debuysère H; Fazio F; Lafitte L J; Broly F
Molecular analysis of the N-acetyltransferase 1 gene (NAT1*) using polymerase chain reaction-restriction fragment-single strand conformation polymorphism assay.
Pharmacogenetics 2000;10(4):293-300.
2000: Colombel J F; Ferrari N; Debuysere H; Marteau P; Gendre J P; Bonaz B; Soulé J C; Modigliani R; Touze Y; Catala P; Libersa C; Broly F
Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy.
Gastroenterology 2000;118(6):1025-30.
2000: Haffen E; Vandel P; Paintaud G; Broly F; Vandel S; Bonin B; Bizouard P; Sechter D; Bechtel P R
Influence of CYP2D6*2 and CYP2D6*4 alleles on phenotype in polymedicated depressed inpatients: therapeutic consequences?
European journal of clinical pharmacology 2000;55(11-12):877-9.
1999: Dervieux T; Médard Y; Baudouin V; Maisin A; Zhang D; Broly F; Loirat C; Jacqz-Aigrain E
Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine.
British journal of clinical pharmacology 1999;48(6):793-800.
1999: Vandel P; Haffen E; Vandel S; Bonin B; Nezelof S; Sechter D; Broly F; Bizouard P; Dalery J
Drug extrapyramidal side effects. CYP2D6 genotypes and phenotypes.
European journal of clinical pharmacology 1999;55(9):659-65.
1999: Haffen E; Vandel P; Broly F; Vandel S; Sechter D; Bizouard P; Bechtel P R
Citalopram: an interaction study with clomipramine in a patient heterozygous for CYP2D6 genotype.
Pharmacopsychiatry 1999;32(6):232-4.
1999: Marez-Allorge D; Ellis S W; Lo Guidice J M; Tucker G T; Broly F
A rare G2061 insertion affecting the open reading frame of CYP2D6 and responsible for the poor metabolizer phenotype.
Pharmacogenetics 1999;9(3):393-6.
1999: Spire-Vayron de la Moureyre C; Debuysère H; Fazio F; Sergent E; Bernard C; Sabbagh N; Marez D; Lo Guidice J M; D'halluin J C; Broly F
Characterization of a variable number tandem repeat region in the thiopurine S-methyltransferase gene promoter.
Pharmacogenetics 1999;9(2):189-98.
1999: Sabbagh N; Brice A; Marez D; Dürr A; Legrand M; Lo Guidice J M; Destée A; Agid Y; Broly F
CYP2D6 polymorphism and Parkinson's disease susceptibility.
Movement disorders : official journal of the Movement Disorder Society 1999;14(2):230-6.
1998: Spire-Vayron de la Moureyre C; Debuysere H; Mastain B; Vinner E; Marez D; Lo Guidice J M; Chevalier D; Brique S; Motte K; Colombel J F; Turck D; Noel C; Flipo R M; Pol A; Lhermitte M; Lafitte J J; Libersa C; Broly F
Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.
British journal of pharmacology 1998;125(4):879-87.
1998: Sabbagh N; Marez D; Queyrel V; Lo Guidice J M; Spire C; Vanhille P; Jörgensen C; Hachulla E; Broly F
Genetic analysis of the cytochrome P450 CYP2D6 polymorphism in patients with systemic lupus erythematosus.
Pharmacogenetics 1998;8(3):191-4.
1998: Legrand-Andréoletti M; Stücker I; Marez D; Galais P; Cosme J; Sabbagh N; Spire C; Cenée S; Lafitte J J; Beaune P; Broly F
Cytochrome P450 CYP2D6 gene polymorphism and lung cancer susceptibility in Caucasians.
Pharmacogenetics 1998;8(1):7-14.
1998: Spire-Vayron de la Moureyre C; Debuysère H; Sabbagh N; Marez D; Vinner E; Chevalier E D; Lo Guidice J M; Broly F
Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis.
Human mutation 1998;12(3):177-85.
1997: Guidice J M; Marez D; Sabbagh N; Legrand-Andreoletti M; Spire C; Alcaïde E; Lafitte J J; Broly F
Evidence for CYP2D6 expression in human lung.
Biochemical and biophysical research communications 1997;241(1):79-85.
1997: Marez D; Legrand M; Sabbagh N; Guidice J M; Spire C; Lafitte J J; Meyer U A; Broly F
Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution.
Pharmacogenetics 1997;7(3):193-202.
1997: Sabbagh N; Delaporte E; Marez D; Lo-Guidice J M; Piette F; Broly F
NAT2 genotyping and efficacy of sulfasalazine in patients with chronic discoid lupus erythematosus.
Pharmacogenetics 1997;7(2):131-5.
1997: Delaporte E; Catteau B; Sabbagh N; Gosselin P; Breuillard F; Doutre M S; Broly F; Piette F; Bergoend H
[Treatment of discoid lupus erythematosus with sulfasalazine: 11 cases]
Annales de dermatologie et de vénéréologie 1997;124(2):151-6.
1996: Legrand M; Stucker I; Marez D; Sabbagh N; Lo-Guidice J M; Broly F
Influence of a mutation reducing the catalytic activity of the cytochrome P450 CYP2D6 on lung cancer susceptibility.
Carcinogenesis 1996;17(10):2267-9.
1996: Bordet R; Broly F; Destée A; Libersa C; Lafitte J J
Lack of relation between genetic polymorphism of cytochrome P-450IID6 and sporadic idiopathic Parkinson's disease.
Clinical neuropharmacology 1996;19(3):213-21.
1996: Marez D; Legrand M; Sabbagh N; Lo-Guidice J M; Boone P; Broly F
An additional allelic variant of the CYP2D6 gene causing impaired metabolism of sparteine.
Human genetics 1996;97(5):668-70.
1996: Bordet R; Broly F; Destée A; Libersa C
Debrisoquine hydroxylation genotype in familial forms of idiopathic Parkinson's disease.
Advances in neurology 1996;69():97-100.
1995: Broly F; Marez D; Sabbagh N; Legrand M; Millecamps S; Lo Guidice J M; Boone P; Meyer U A
An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis.
Pharmacogenetics 1995;5(6):373-84.
1995: Broly F; Marez D; Lo Guidice J M; Sabbagh N; Legrand M; Boone P; Meyer U A
A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency.
Human genetics 1995;96(5):601-3.
1995: Marez D; Sabbagh N; Legrand M; Lo-Guidice J M; Boone P; Broly F
A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype.
Pharmacogenetics 1995;5(5):305-11.
1994: Bordet R; Broly F; Destee A; Libersa C
Genetic polymorphism of cytochrome P450 2D6 in idiopathic Parkinson disease and diffuse Lewy body disease.
Clinical neuropharmacology 1994;17(5):484-8.
1993: Libersa C; Caron J; Broly F; Lacroix D; Lhermitte M
Interaction of propafenone and mexiletine.
Journal of the American College of Cardiology 1993;22(7):2061-2.
1993: Vandamme N; Broly F; Libersa C; Courseau C; Lhermitte M
Stereoselective hydroxylation of mexiletine in human liver microsomes: implication of P450IID6--a preliminary report.
Journal of cardiovascular pharmacology 1993;21(1):77-83.
1991: Broly F; Marecaux P; Houdret N; Lhermitte M; Houssin R
A high performance liquid chromatographic method for the quantitation of flecainide in plasma.
Biomedical chromatography : BMC 1991;5(6):248-50.
1991: Broly F; Vandamme N; Libersa C; Lhermitte M
The metabolism of mexiletine in relation to the debrisoquine/sparteine-type polymorphism of drug oxidation.
British journal of clinical pharmacology 1991;32(4):459-66.
1991: Broly F; Vandamme N; Caron J; Libersa C; Lhermitte M
Single-dose quinidine treatment inhibits mexiletine oxidation in extensive metabolizers of debrisoquine.
Life sciences 1991;48(26):PL123-8.
1990: Broly F; Libersa C; Lhermitte M
Mexiletine metabolism in vitro by human liver.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(3):362-8.
1990: Broly F; Libersa C; Lhermitte M; Dupuis B
Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes.
Biochemical pharmacology 1990;39(6):1045-53.
1989: Broly F; Libersa C; Lhermitte M; Bechtel P; Dupuis B
Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver.
British journal of clinical pharmacology 1989;28(1):29-36.
1988: Broly F; Libersa C; Lhermitte M
High-performance liquid chromatographic assay for mexiletine hydroxylation in microsomes of human liver.
Journal of chromatography 1988;431(2):369-78.
1987: Lhermitte M; Houdret N; Broly F; Roussel P; Carpentier C; Zaoui C; Lequien P
Simultaneous administration of caffeine and phenobarbitone in infants with apnea.
The Journal of pediatrics 1987;110(4):666-7.

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Franck Broly

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