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Fernando Zamudio

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Alejandro Carbajal-Saucedo; Adolfo R de Roodt; Estuardo López-Vera; Eric N Smith; Fernando Z Zamudio; Melisa Bénard-Valle; Alejandro Olvera-Rodríguez
Isolation, characterization, cloning and expression of an alpha-neurotoxin from the venom of the Mexican coral snake Micrurus laticollaris (Squamata: Elapidae).
Herlinda Clement; George V Odell; Alejandro Olvera; Laura A Palomares; Lourival D Possani; Mabel Rodríguez; Alejandro Alagón; Fernando Z Zamudio; Rosana Sánchez-López
Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Herlinda Clement; Vanessa Costa de Oliveira; Alejandro Alagón; Melisa Bérnard Valle; Silvia E Hajos; Néstor R Lago; Lourival D Possani; NORMA VALDEZ Cruz; Fernando Z Zamudio; Adolfo de Roodt
Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A₂ from Bothrops (Rhinocerophis) ammodytoides venom.

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All Publications

2013: Alejandro Carbajal-Saucedo; Adolfo R de Roodt; Estuardo López-Vera; Eric N Smith; Fernando Z Zamudio; Melisa Bénard-Valle; Alejandro Olvera-Rodríguez
Isolation, characterization, cloning and expression of an alpha-neurotoxin from the venom of the Mexican coral snake Micrurus laticollaris (Squamata: Elapidae).
Toxicon : official journal of the International Society on Toxinology 2013;66():64-74.
2012: Herlinda Clement; George V Odell; Alejandro Olvera; Laura A Palomares; Lourival D Possani; Mabel Rodríguez; Alejandro Alagón; Fernando Z Zamudio; Rosana Sánchez-López
Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon : official journal of the International Society on Toxinology 2012;60(7):1223-7.
2012: Herlinda Clement; Vanessa Costa de Oliveira; Alejandro Alagón; Melisa Bérnard Valle; Silvia E Hajos; Néstor R Lago; Lourival D Possani; NORMA VALDEZ Cruz; Fernando Z Zamudio; Adolfo de Roodt
Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A₂ from Bothrops (Rhinocerophis) ammodytoides venom.
Toxicon : official journal of the International Society on Toxinology 2012;60(7):1314-23.
2012: Figen Caliskan; Fredy I V Coronas; V Quintero-Hernández; Rita Restano-Cassulini; Fernando Z Zamudio; Cesar V F Batista; Lourival D Possani
Turkish scorpion Buthacus macrocentrus: general characterization of the venom and description of Bu1, a potent mammalian Na⁺-channel α-toxin.
Toxicon : official journal of the International Society on Toxinology 2012;59(3):408-15.
2011: Gerardo Pavel Espino-Solis; Georgina Estrada; Timoteo Olamendi-Portugal; Villegas Villarreal Elba Crsitina; Fernando Z Zamudio; Sandrine Cestele; Lourival D Possani; Gerardo Corzo
Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus.
Toxicon : official journal of the International Society on Toxinology 2011;57(5):739-46.
2011: Juan-Elías Olivares; Margarita Rodríguez-Kessler; Luis Eduardo Servín; Fernando Z Zamudio; Xochitl Alvarado-Affantranger; Claudia Díaz-Camino; Georgina Estrada-Navarrete; Yamile Márquez; Timoteo Olamendi-Portugal; Federico Sánchez
Nodulin 41, a novel late nodulin of common bean with peptidase activity.
BMC plant biology 2011;11():134.
2010: Thomas Vandendriessche; Timoteo Olamendi-Portugal; Fernando Z Zamudio; Lourival D Possani; Jan Tytgat
Isolation and characterization of two novel scorpion toxins: The alpha-toxin-like CeII8, specific for Na(v)1.7 channels and the classical anti-mammalian CeII9, specific for Na(v)1.4 channels.
Toxicon : official journal of the International Society on Toxinology 2010;56(4):613-23.
2010: Elisa Redaelli; Rita Restano Cassulini; Deyanira Fuentes Silva; Herlinda Clement; Emanuele Schiavon; Fernando Z Zamudio; George Odell; Annarosa Arcangeli; Jeffrey J Clare; Alejandro Alagón; Ricardo C Rodríguez de la Vega; Lourival D Possani; Enzo Wanke
Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
The Journal of biological chemistry 2010;285(6):4130-42.
2009: Elisabeth Schwartz; E Michelle Capes; Elia Diego-García; Fernando Z Zamudio; Oscar Fuentes; Lourival D Possani; Héctor H Valdivia
Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors.
British journal of pharmacology 2009;157(3):392-403.
2008: Rita Restano-Cassulini; Timoteo Olamendi-Portugal; Fernando Z Zamudio; Baltazar Becerril; Lourival D Possani
Two novel ergtoxins, blockers of K+-channels, purified from the Mexican scorpion Centruroides elegans elegans.
Neurochemical research 2008;33(8):1525-33.
2008: Elisabeth Schwartz; Thalita S Camargos; Fernando Z Zamudio; Luciano P Silva; Carlos Bloch; Fabio Caixeta; Carlos Alberto Schwartz; Lourival D Possani
Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum.
Toxicon : official journal of the International Society on Toxinology 2008;51(8):1499-508.
2007: Herlinda Clement; George Odell; Fernando Z Zamudio; Elisa Redaelli; Enzo Wanke; Alejandro Alagón; Lourival D Possani
Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon : official journal of the International Society on Toxinology 2007;50(1):65-74.
2007: Cesar V F Batista; S A Román-González; S P Salas-Castillo; Fernando Z Zamudio; Froylan Gómez-Lagunas; Lourival D Possani
Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2007;146(1-2):147-57.
2007: F E Cázares-Raga; M González-Lázaro; C Montero-Solís; Lilia González-Cerón; Fernando Z Zamudio; Jesús Martínez-Barnetche; J A Torres-Monzón; M Ovilla-Muñoz; J Aguilar-Fuentes; Mario H Rodríguez; F de la Cruz Hernández-Hernández
GP35 ANOAL, an abundant acidic glycoprotein of female Anopheles albimanus saliva.
Insect molecular biology 2007;16(2):187-98.
2006: Elisabeth Schwartz; Carlos Alberto Schwartz; Froylan Gómez-Lagunas; Fernando Z Zamudio; Lourival D Possani
HgeTx1, the first K+-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad.
Toxicon : official journal of the International Society on Toxinology 2006;48(8):1046-53.
2006: Figen Caliskan; Blanca Inés García; Fredy I V Coronas; Cesar V F Batista; Fernando Z Zamudio; Lourival D Possani
Characterization of venom components from the scorpion Androctonus crassicauda of Turkey: peptides and genes.
Toxicon : official journal of the International Society on Toxinology 2006;48(1):12-22.
2006: Cesar V F Batista; Gina D'Suze; Froylan Gómez-Lagunas; Fernando Z Zamudio; Sergio Encarnación; Carlos Sevcik; Lourival D Possani
Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins.
Proteomics 2006;6(12):3718-27.
2006: Jacqueline Barona; Cesar V F Batista; Fernando Z Zamudio; Froylan Gomez-Lagunas; Enzo Wanke; Rafael Otero; Lourival D Possani
Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus.
Biochimica et biophysica acta 2006;1764(1):76-84.
2005: Timoteo Olamendi-Portugal; Sándor Somodi; Juan Antonio Fernández; Fernando Z Zamudio; Baltazar Becerril; Zoltán Varga; György Panyi; Rezso Gáspár; Lourival D Possani
Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells.
Toxicon : official journal of the International Society on Toxinology 2005;46(4):418-29.
2004: NORMA VALDEZ Cruz; Cesar V F Batista; Fernando Z Zamudio; Frank Bosmans; Jan Tytgat; Lourival D Possani
Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus.
European journal of biochemistry / FEBS 2004;271(23-24):4753-61.
2004: Gina D'Suze; Cesar V F Batista; Andrea Frau; Anna Rosa Murgia; Fernando Z Zamudio; Carlos Sevcik; Lourival D Possani; Gianfranco Prestipino
Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells.
Archives of biochemistry and biophysics 2004;430(2):256-63.
2004: Blanca Ramos-Cerrillo; Alejandro Olvera; George V Odell; Fernando Z Zamudio; Jorge Paniagua-Solís; Alejandro Alagón; Roberto P Stock
Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.
Toxicon : official journal of the International Society on Toxinology 2004;44(5):507-14.
2004: Xinsheng Zhu; Fernando Z Zamudio; Beth A Olbinski; Lourival D Possani; Héctor H Valdivia
Activation of skeletal ryanodine receptors by two novel scorpion toxins from Buthotus judaicus.
The Journal of biological chemistry 2004;279(25):26588-96.
2004: NORMA VALDEZ Cruz; Sonia Dávila; Alexei F Licea; Miguel Corona; Fernando Z Zamudio; Jesús García-Valdes; Leslie Boyer; Lourival D Possani
Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing.
Biochimie 2004;86(6):387-96.
2004: Federico del Río-Portilla; Elizabeth Hernández-Marín; Genaro Pimienta; Fredy V Coronas; Fernando Z Zamudio; Ricardo C Rodríguez de la Vega; Enzo Wanke; Lourival D Possani
NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.
European journal of biochemistry / FEBS 2004;271(12):2504-16.
2004: Cesar V F Batista; Luis del Pozo; Fernando Z Zamudio; Sandra Contreras; Baltazar Becerril; Enzo Wanke; Lourival D Possani
Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;803(1):55-66.
2004: Gina D'Suze; Carlos Sevcik; Miguel Corona; Fernando Z Zamudio; Cesar V F Batista; Fredy I V Coronas; Lourival D Possani
Ardiscretin a novel arthropod-selective toxin from Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 2004;43(3):263-72.
2003: Fredy V Coronas; Adolfo de Roodt; Timoteo Olamendi Portugal; Fernando Z Zamudio; Cesar V F Batista; Froylan Gómez-Lagunas; Lourival D Possani
Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus.
Toxicon : official journal of the International Society on Toxinology 2003;41(2):173-9.
2002: Miguel Corona; Georgina B Gurrola; Enrique Merino; Rita Restano Cassulini; NORMA VALDEZ Cruz; Blanca García; Martha E Ramírez-Domínguez; Fredy I V Coronas; Fernando Z Zamudio; Enzo Wanke; Lourival D Possani
A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides.
FEBS letters 2002;532(1-2):121-6.
2002: Cesar V F Batista; Fernando Z Zamudio; Sylvia Lucas; Jay W Fox; Andrea Frau; Gianfranco Prestipino; Lourival D Possani
Scorpion toxins from Tityus cambridgei that affect Na(+)-channels.
Toxicon : official journal of the International Society on Toxinology 2002;40(5):557-62.
2001: J Garcia-Valdes; Fernando Z Zamudio; L Toro; Lourival D Possani; L D Possan
Slotoxin, alphaKTx1.11, a new scorpion peptide blocker of MaxiK channels that differentiates between alpha and alpha+beta (beta1 or beta4) complexes.
FEBS letters 2001;505(3):369-73.
2000: A Torres-Larios; Georgina B Gurrola; Fernando Z Zamudio; Lourival D Possani
Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus.
European journal of biochemistry / FEBS 2000;267(16):5023-31.
2000: R Conde; Fernando Z Zamudio; M H Rodríguez; Lourival D Possani
Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom.
FEBS letters 2000;471(2-3):165-8.
1999: R Conde; Fernando Z Zamudio; Baltazar Becerril; Lourival D Possani
Phospholipin, a novel heterodimeric phospholipase A2 from Pandinus imperator scp6pion venom.
FEBS letters 1999;460(3):447-50.
1999: Barbara Selisko; A F Licea; Baltazar Becerril; Fernando Z Zamudio; Lourival D Possani; Eduardo Horjales
Antibody BCF2 against scorpion toxin Cn2 from Centuroides noxius Hoffmann: primary structure and three-dimensional model as free Fv fragment and complexed with its antigen.
Proteins 1999;37(1):130-43.
1999: Gina D'Suze; Fernando Z Zamudio; Froylan Gómez-Lagunas; Lourival D Possani
A novel K+ channel blocking toxin from Tityus discrepans scorpion venom.
FEBS letters 1999;456(1):146-8.
1997: Fernando Z Zamudio; R Conde; C Arévalo; Baltazar Becerril; B M Martin; Héctor H Valdivia; Lourival D Possani
The mechanism of inhibition of ryanodine receptor channels by imperatoxin I, a heterodimeric protein from the scorpion Pandinus imperator.
The Journal of biological chemistry 1997;272(18):11886-94.
1997: Fernando Z Zamudio; Georgina B Gurrola; C Arévalo; R Sreekumar; Jeffery W Walker; Héctor H Valdivia; Lourival D Possani
Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.
FEBS letters 1997;405(3):385-9.
1996: Fernando Z Zamudio; K M Wolf; Brian M Martin; Lourival D Possani; Vincent A Chiappinelli
Two novel alpha-neurotoxins isolated from the taipan snake, Oxyuranus scutellatus, exhibit reduced affinity for nicotinic acetylcholine receptors in brain and skeletal muscle.
Biochemistry 1996;35(24):7910-6.
1996: Baltazar Becerril; M Corona; F I Coronas; Fernando Z Zamudio; E S Calderon-Aranda; Paul Fletcher; Brian M Martin; Lourival D Possani
Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus.
The Biochemical journal 1996;313 ( Pt 3)():753-60.
1994: Georgina B Gurrola; G Moreno-Hagelsieb; Fernando Z Zamudio; M García; X Soberon; Lourival D Possani
The disulfide bridges of toxin 2 from the scorpion Centruroides noxius Hoffmann and its three-dimensional structure calculated using the coordinates of variant 3 from Centruroides sculpturatus.
FEBS letters 1994;347(1):59-62.
1993: A Vázquez; Baltazar Becerril; Brian M Martin; Fernando Z Zamudio; Francisco Bolívar; Lourival D Possani
Primary structure determination and cloning of the cDNA encoding toxin 4 of the scorpion Centruroides noxius Hoffmann.
FEBS letters 1993;320(1):43-6.
1992: Lourival D Possani; Brian M Martin; A Yatani; J Mochca-Morales; Fernando Z Zamudio; Georgina B Gurrola; A M Brown
Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1343-64.
1985: O Ladrón de Guevara; G Estrada; S Antonio; X Alvarado; L Guereca; Fernando Z Zamudio; Francisco Bolívar
Identification and isolation of human insulin A and B chains by high-performance liquid chromatography.
Journal of chromatography 1985;349(1):91-8.