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Richard Zangar

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Enzyme-Linked Immunosorbent Assay

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Protein Array Analysis

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Susan C Tilton; Katrina M Waters; Bobbie-Jo M Webb-Robertson; Richard C Zangar; Diana J Bigelow; Norman J Karin; K Monica Lee; Joel G Pounds; Richard A Corley
Diet-induced obesity reprograms the inflammatory response of the murine lung to inhaled endotoxin.
Vikram Chaudhery; Cheng-Sheng Huang; Meng Lu; James Polans; Ruimin Tan; Richard C Zangar; Brian T Cunningham
Line-scanning detection instrument for photonic crystal enhanced fluorescence.
Hongjun Jin; Richard C Zangar
High-throughput, multiplexed analysis of 3-nitrotyrosine in individual proteins.

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2013: Susan C Tilton; Katrina M Waters; Bobbie-Jo M Webb-Robertson; Richard C Zangar; Diana J Bigelow; Norman J Karin; K Monica Lee; Joel G Pounds; Richard A Corley
Diet-induced obesity reprograms the inflammatory response of the murine lung to inhaled endotoxin.
Toxicology and applied pharmacology 2013;267(2):137-48.
2012: Vikram Chaudhery; Cheng-Sheng Huang; Meng Lu; James Polans; Ruimin Tan; Richard C Zangar; Brian T Cunningham
Line-scanning detection instrument for photonic crystal enhanced fluorescence.
Optics letters 2012;37(13):2565-7.
2012: Hongjun Jin; Richard C Zangar
High-throughput, multiplexed analysis of 3-nitrotyrosine in individual proteins.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2012;Chapter 17():Unit 17.15.
2012: Cheng-Sheng Huang; Meng Lu; Anusha Pokhriyal; James Polans; Ruimin Tan; Richard C Zangar; Vikram Chaudhery; Sherine George; Brian Cunningham
Multiplexed cancer biomarker detection using quartz-based photonic crystal surfaces.
Analytical chemistry 2012;84(2):1126-33.
2011: Cheryl L Baird; Christopher J Fischer; Ruimin Tan; Kristin D Victry; Richard C Zangar; Karin D Rodland
Reducing heterophilic antibody interference in immunoassays using single-chain antibodies.
Analytical biochemistry 2011;419(2):333-5.
2011: Richard C Zangar; Nikki Bollinger; L Meng Markillie; Ruimin M Tan; Thomas J Weber; Norman J Karin
Reactive oxygen species alter autocrine and paracrine signaling.
Free radical biology & medicine 2011;51(11):2041-7.
2011: Hongjun Jin; Elena S Peterson; Joel G Pounds; Mary Beth Scholand; Ruimin Tan; Bobbie-Jo Webb-Robertson; Diana J Bigelow; John R Hoidal; Richard C Zangar
Smoking, COPD, and 3-nitrotyrosine levels of plasma proteins.
Environmental health perspectives 2011;119(9):1314-20.
2011: Galya A Orr; Ruimin Tan; Barbara J Tarasevich; Kaylyn J Cassens; William B Chrisler; Lye Meng Markillie; Richard C Zangar; Brian D Thrall
Cellular recognition and trafficking of amorphous silica nanoparticles by macrophage scavenger receptor A.
Nanotoxicology 2011;5(3):296-311.
2011: Rachel M Gonzalez; Jeffrey R Marks; Ruimin Tan; Don S Daly; Richard C Zangar
Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(7):1543-51.
2011: Rachel M Gonzalez; Qibin Zhang; Richard C Zangar; Richard D Smith; Tom Metz
Development of a fibrinogen-specific sandwich enzyme-linked immunosorbent assay microarray assay for distinguishing between blood plasma and serum samples.
Analytical biochemistry 2011;414(1):99-102.
2011: Cheng-Sheng Huang; Sherine George; Meng Lu; Vikram Chaudhery; Ruimin Tan; Richard C Zangar; Brian Cunningham
Application of photonic crystal enhanced fluorescence to cancer biomarker microarrays.
Analytical chemistry 2011;83(4):1425-30.
2011: Yi Zhang; Rachel M Gonzalez; Richard C Zangar
Protein secretion in human mammary epithelial cells following HER1 receptor activation: influence of HER2 and HER3 expression.
BMC cancer 2011;11():69.
2011: Amanda M White; Don S Daly; Richard C Zangar
Analysis of high-throughput ELISA microarray data.
Methods in molecular biology (Clifton, N.J.) 2011;694():191-211.
2010: Hongjun Jin; Richard C Zangar
Antibody microarrays for high-throughput, multianalyte analysis.
Cancer biomarkers : section A of Disease markers 2010;6(5-6):281-90.
2010: Don Simone Daly; Kevin K Anderson; Shannon L Seurynck-Servoss; Rachel M Gonzalez; Amanda M White; Richard C Zangar
An internal calibration method for protein-array studies.
Statistical applications in genetics and molecular biology 2010;9():Article 14.
2009: Richard C Zangar; D S Daly; A M White; S L Servoss; R M Tan; J R Collett
ProMAT calibrator: A tool for reducing experimental bias in antibody microarrays.
Journal of proteome research 2009;8(8):3937-43.
2009: Amanda M White; James R Collett; Shannon L Seurynck-Servoss; Don S Daly; Richard C Zangar
ELISA-BASE: an integrated bioinformatics tool for analyzing and tracking ELISA microarray data.
Bioinformatics (Oxford, England) 2009;25(12):1566-7.
2009: David L Springer; John H Miller; Sherry L Spinelli; Ljiljana Pasa-Tolic; Samuel O Purvine; Donald S Daly; Richard C Zangar; Shuangshuang Jin; Neil Blumberg; Charles W Francis; Mark B Taubman; Ann E Casey; Steven D Wittlin; Richard P Phipps
Platelet proteome changes associated with diabetes and during platelet storage for transfusion.
Journal of proteome research 2009;8(5):2261-72.
2009: Katrina M Waters; Lisa M Masiello; Richard C Zangar; Barbara J Tarasevich; Norman J Karin; Ryan D Quesenberry; Somnath Bandyopadhyay; Justin G Teeguarden; Joel Pounds; Brian D Thrall
Macrophage responses to silica nanoparticles are highly conserved across particle sizes.
Toxicological sciences : an official journal of the Society of Toxicology 2009;107(2):553-69.
2009: Hongjun Jin; Richard C Zangar
Protein modifications as potential biomarkers in breast cancer.
Biomarker insights 2009;4():191-200.
2009: Shannon L Servoss; Rachel Gonzalez; Susan Varnum; Richard C Zangar
High-throughput analysis of serum antigens using sandwich ELISAs on microarrays.
Methods in molecular biology (Clifton, N.J.) 2009;520():143-50.
2008: Karin D Rodland; Nikki Bollinger; Danielle Ippolito; Lee K Opresko; Robert J Coffey; Richard C Zangar; H Steven Wiley
Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.
The Journal of biological chemistry 2008;283(46):31477-87.
2008: Shannon L Seurynck-Servoss; Cheryl L Baird; Keith D Miller; Noah B Pefaur; Rachel M Gonzalez; David O Apiyo; Heather E Engelmann; sudhir srivastava; Jacob Kagan; Karin D Rodland; Richard C Zangar
Immobilization strategies for single-chain antibody microarrays.
Proteomics 2008;8(11):2199-210.
2008: Rachel M Gonzalez; Shannon L Seurynck-Servoss; Sheila A Crowley; Marty Brown; Gilbert S Omenn; Daniel F Hayes; Richard C Zangar
Development and validation of sandwich ELISA microarrays with minimal assay interference.
Journal of proteome research 2008;7(6):2406-14.
2008: Richard C Zangar; N Bollinger; S Verma; N J Karin; Y Lu
The nuclear factor-kappa B pathway regulates cytochrome P450 3A4 protein stability.
Molecular pharmacology 2008;73(6):1652-8.
2008: Don S Daly; Kevin K Anderson; Amanda M White; Rachel M Gonzalez; Susan M Varnum; Richard C Zangar
Predicting protein concentrations with ELISA microarray assays, monotonic splines and Monte Carlo simulation.
Statistical applications in genetics and molecular biology 2008;7(1):Article21.
2007: Shannon L Seurynck-Servoss; Amanda M White; Cheryl L Baird; Karin D Rodland; Richard C Zangar
Evaluation of surface chemistries for antibody microarrays.
Analytical biochemistry 2007;371(1):105-15.
2007: Shannon L Seurynck-Servoss; Cheryl L Baird; Karin D Rodland; Richard C Zangar
Surface chemistries for antibody microarrays.
Frontiers in bioscience : a journal and virtual library 2007;12():3956-64.
2006: Amanda M White; Don S Daly; Susan M Varnum; Kevin K Anderson; Nikki Bollinger; Richard C Zangar
ProMAT: protein microarray analysis tool.
Bioinformatics (Oxford, England) 2006;22(10):1278-9.
2006: Richard C Zangar; Don S Daly; Amanda M White
ELISA microarray technology as a high-throughput system for cancer biomarker validation.
Expert review of proteomics 2006;3(1):37-44.
2005: Joshua N Adkins; Matthew Monroe; Kenneth J Auberry; Yufeng Shen; Jon M Jacobs; David G Camp; Frank Vitzthum; Karin D Rodland; Richard C Zangar; Richard D Smith; Joel G Pounds
A proteomic study of the HUPO Plasma Proteome Project's pilot samples using an accurate mass and time tag strategy.
Proteomics 2005;5(13):3454-66.
2005: Richard C Zangar; Susan M Varnum; Nikki Bollinger
Studying cellular processes and detecting disease with protein microarrays.
Drug metabolism reviews 2005;37(3):473-87.
2005: Don S Daly; Amanda M White; Susan M Varnum; Kevin K Anderson; Richard C Zangar
Evaluating concentration estimation errors in ELISA microarray experiments.
BMC bioinformatics 2005;6():17.
2004: Richard C Zangar; Dmitri Davydov; Seema Verma
Mechanisms that regulate production of reactive oxygen species by cytochrome P450.
Toxicology and applied pharmacology 2004;199(3):316-31.
2004: Richard C Zangar; Yang-Yi Fan; Robert S Chapkin
Interactions of phospholipase D and cytochrome P450 protein stability.
Biochemical pharmacology 2004;68(3):503-12.
2004: Wan-Nan U Chen; Ronald L Woodbury; Loel E Kathmann; Lee K Opresko; Richard C Zangar; H Steven Wiley; Brian D Thrall
Induced autocrine signaling through the epidermal growth factor receptor contributes to the response of mammary epithelial cells to tumor necrosis factor alpha.
The Journal of biological chemistry 2004;279(18):18488-96.
2004: Richard C Zangar; Susan M Varnum; Chandice Covington; Richard D Smith
A rational approach for discovering and validating cancer markers in very small samples using mass spectrometry and ELISA microarrays.
Disease markers 2004;20(3):135-48.
2004: Susan M Varnum; Ronald L Woodbury; Richard C Zangar
A protein microarray ELISA for screening biological fluids.
Methods in molecular biology (Clifton, N.J.) 2004;264():161-72.
2003: Amy L Kimzey; Karl K Weitz; F Peter Guengerich; Richard C Zangar
Hydroperoxy-10,12-octadecadienoic acid stimulates cytochrome P450 3A protein aggregation by a mechanism that is inhibited by substrate.
Biochemistry 2003;42(43):12691-9.
2003: Susan M Varnum; Chandice C Covington; Ronald L Woodbury; Konstantinos Petritis; Lars J Kangas; Mohamed S Abdullah; Joel G Pounds; Richard D Smith; Richard C Zangar
Proteomic characterization of nipple aspirate fluid: identification of potential biomarkers of breast cancer.
Breast cancer research and treatment 2003;80(1):87-97.
2003: Richard C Zangar; Thomas A Kocarek; Shang Shen; Nikki Bollinger; Michael S Dahn; Donna W Lee
Suppression of cytochrome P450 3A protein levels by proteasome inhibitors.
The Journal of pharmacology and experimental therapeutics 2003;305(3):872-9.
2002: Ronald L Woodbury; Susan M Varnum; Richard C Zangar
Elevated HGF levels in sera from breast cancer patients detected using a protein microarray ELISA.
Journal of proteome research 2002;1(3):233-7.
2002: Richard C Zangar; A L Kimzey; JR Okita; David S Wunschel; R J Edwards; H Kim; RT Okita
Cytochrome P450 3A conjugation to ubiquitin in a process distinct from classical ubiquitination pathway.
Molecular pharmacology 2002;61(4):892-904.
2001: H Kim; David A Putt; Richard C Zangar; C R Wolf; F P Guengerich; R J Edwards; Paul Hollenberg; Raymond F Novak
Differential induction of rat hepatic cytochromes P450 3A1, 3A2, 2B1, 2B2, and 2E1 in response to pyridine treatment.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(3):353-60.
2000: BS Cummings; Richard C Zangar; Raymond F Novak; Lawrence H Lash
Cytotoxicity of trichloroethylene and S-(1, 2-dichlorovinyl)-L-cysteine in primary cultures of rat renal proximal tubular and distal tubular cells.
Toxicology 2000;150(1-3):83-98.
2000: Karla D Thrall; M E Vucelick; Richard A Gies; Richard C Zangar; Karl K Weitz; Torka S Poet; DL Springer; D M Grant; Janet M Benson
Comparative metabolism of carbon tetrachloride in rats, mice, and hamsters using gas uptake and PBPK modeling.
Journal of toxicology and environmental health. Part A 2000;60(8):531-48.
2000: Thomas A Kocarek; Richard C Zangar; Raymond F Novak
Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability.
Archives of biochemistry and biophysics 2000;376(1):180-90.
2000: Richard C Zangar; Janet M Benson; V L Burnett; DL Springer
Cytochrome P450 2E1 is the primary enzyme responsible for low-dose carbon tetrachloride metabolism in human liver microsomes.
Chemico-biological interactions 2000;125(3):233-43.
1999: Richard C Zangar; JR Okita; H Kim; P E Thomas; A Anderson; R J Edwards; DL Springer; RT Okita
Effect of calcium channel antagonists nifedipine and nicardipine on rat cytochrome P-450 2B and 3A forms.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1436-41.
1999: BS Cummings; Richard C Zangar; Raymond F Novak; Lawrence H Lash
Cellular distribution of cytochromes P-450 in the rat kidney.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(4):542-8.
1998: Richard C Zangar; Raymond F Novak
Posttranslational elevation of cytochrome P450 3A levels and activity by dimethyl sulfoxide.
Archives of biochemistry and biophysics 1998;353(1):1-9.
1997: Richard C Zangar; M Hernandez; Raymond F Novak
Posttranscriptional elevation of cytochrome P450 3A expression.
Biochemical and biophysical research communications 1997;231(1):203-5.
1997: Richard C Zangar; Raymond F Novak
Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes.
Archives of biochemistry and biophysics 1997;337(2):217-24.
1996: Richard C Zangar; Kimberley Woodcroft; Raymond F Novak
Differential effects of ciprofibrate on renal and hepatic cytochrome P450 2E1 expression.
Toxicology and applied pharmacology 1996;141(1):110-6.
1996: Melissa Runge-Morris; Y Feng; Richard C Zangar; Raymond F Novak
Effects of hydrazine, phenelzine, and hydralazine treatment on rat hepatic and renal drug-metabolizing enzyme expression.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(7):734-7.
1995: Richard C Zangar; John J Reiners; Raymond F Novak
Gender-specific and developmental differences in protein kinase C isozyme expression in rat liver.
Carcinogenesis 1995;16(10):2593-7.
1995: Richard C Zangar; Kimberley Woodcroft; Thomas A Kocarek; Raymond F Novak
Xenobiotic-enhanced expression of cytochrome P450 2E1 and 2B1/2B2 in primary cultured rat hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(7):681-7.
1995: Richard C Zangar; Donald R Buhler; D L Springer
Neonatal exposure to xenobiotics alters adult hepatic protein kinase C alpha levels and testosterone metabolism: differential effects by diethylstilbestrol and phenobarbital.
Journal of toxicology and environmental health 1995;45(1):47-58.
1995: Kristen J Nikula; Raymond F Novak; I Y Chang; AR Dahl; Dean A Kracko; Richard C Zangar; S G Kim; J L Lewis
Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(5):529-35.
1995: Richard C Zangar; M Hernandez; Thomas A Kocarek; Raymond F Novak
Determination of the poly(A) tail lengths of a single mRNA species in total hepatic RNA.
BioTechniques 1995;18(3):465-9.
1993: Richard C Zangar; D L Springer; Donald R Buhler
Alterations in cytochrome P-450 levels in adult rats following neonatal exposure to xenobiotics.
Journal of toxicology and environmental health 1993;38(1):43-55.
1992: Richard C Zangar; D L Springer; J A McCrary; Raymond F Novak; T Primiano; Donald R Buhler
Changes in adult metabolism of aflatoxin B1 in rats neonatally exposed to diethylstilbestrol. Alterations in alpha-class glutathione S-transferases.
Carcinogenesis 1992;13(12):2375-9.
1989: Richard C Zangar; D L Springer; R L Buschbom; D D Mahlum
Comparison of fetotoxic effects of a dermally applied complex organic mixture in rats and mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1989;13(4):662-9.
1989: D A Dankovic; C W Wright; Richard C Zangar; D L Springer
Complex mixture effects on the dermal absorption of benzo[a]pyrene and other polycyclic aromatic hydrocarbons from mouse skin.
Journal of applied toxicology : JAT 1989;9(4):239-44.
1989: D A Dankovic; B L Thomas; Richard C Zangar; D W Later; D L Springer
Inhibition of benzo[a]pyrene-7,8-diol formation in vitro by complex organic mixtures.
Toxicology 1989;55(1-2):93-102.
1989: L B Sasser; D L Lundstrom; Richard C Zangar; D L Springer; D D Mahlum
Elevated blood pressure and heart rate in rats exposed to a coal-derived complex organic mixture.
Journal of applied toxicology : JAT 1989;9(1):47-52.
1987: Richard C Zangar; L B Sasser; D D Mahlum; R H Abhold; D L Springer
Cardiovascular effects in rats following exposure to a high-boiling coal liquid.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1987;9(4):659-67.