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Sierd Bron

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Andrzej T Lulko; Jan-Willem Veening; Girbe Buist; Wiep Klaas Smits; Evert Jan Blom; Aaron C Beekman; Sierd Bron; Oscar P Kuipers
Production and secretion stress caused by overexpression of heterologous alpha-amylase leads to inhibition of sporulation and a prolonged motile phase in Bacillus subtilis.
Susanne Wolff; Haike Antelmann; Dirk Albrecht; Dörte Becher; Joerg Bernhardt; Sierd Bron; Knut Büttner; Jan Maarten van Dijl; Christine Eymann; Andreas Otto; Le Thi Tam; Michael Hecker
Towards the entire proteome of the model bacterium Bacillus subtilis by gel-based and gel-free approaches.
Elise Darmon; Ronald Dorenbos; Jochen Meens; Roland Freudl; Haike Antelmann; Michael Hecker; Oscar P Kuipers; Sierd Bron; Wim J Quax; Jean-Yves François Dubois; Jan Maarten van Dijl
A disulfide bond-containing alkaline phosphatase triggers a BdbC-dependent secretion stress response in Bacillus subtilis.

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2007: Andrzej T Lulko; Jan-Willem Veening; Girbe Buist; Wiep Klaas Smits; Evert Jan Blom; Aaron C Beekman; Sierd Bron; Oscar P Kuipers
Production and secretion stress caused by overexpression of heterologous alpha-amylase leads to inhibition of sporulation and a prolonged motile phase in Bacillus subtilis.
Applied and environmental microbiology 2007;73(16):5354-62.
2007: Susanne Wolff; Haike Antelmann; Dirk Albrecht; Dörte Becher; Joerg Bernhardt; Sierd Bron; Knut Büttner; Jan Maarten van Dijl; Christine Eymann; Andreas Otto; Le Thi Tam; Michael Hecker
Towards the entire proteome of the model bacterium Bacillus subtilis by gel-based and gel-free approaches.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;849(1-2):129-40.
2006: Elise Darmon; Ronald Dorenbos; Jochen Meens; Roland Freudl; Haike Antelmann; Michael Hecker; Oscar P Kuipers; Sierd Bron; Wim J Quax; Jean-Yves François Dubois; Jan Maarten van Dijl
A disulfide bond-containing alkaline phosphatase triggers a BdbC-dependent secretion stress response in Bacillus subtilis.
Applied and environmental microbiology 2006;72(11):6876-85.
2006: Haike Antelmann; Jan Maarten van Dijl; Sierd Bron; Michael Hecker
Proteomic survey through secretome of Bacillus subtilis.
Methods of biochemical analysis 2006;49():179-208.
2005: Wiep Klaas Smits; Jean-Yves François Dubois; Sierd Bron; Jan Maarten van Dijl; Oscar P Kuipers
Tricksy business: transcriptome analysis reveals the involvement of thioredoxin A in redox homeostasis, oxidative stress, sulfur metabolism, and cellular differentiation in Bacillus subtilis.
Journal of bacteriology 2005;187(12):3921-30.
2005: Wiep Klaas Smits; Caroline Eschevins; Kim A Susanna; Sierd Bron; Oscar P Kuipers; Leendert W Hamoen
Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development.
Molecular microbiology 2005;56(3):604-14.
2005: Vladimir Lazarevic; Blazenka Soldo; Noël Médico; Harold M Pooley; Sierd Bron; Dimitri Karamata
Bacillus subtilis alpha-phosphoglucomutase is required for normal cell morphology and biofilm formation.
Applied and environmental microbiology 2005;71(1):39-45.
2004: Jan D H Jongbloed; Ulrike Grieger; Haike Antelmann; Michael Hecker; Reindert Nijland; Sierd Bron; Jan Maarten van Dijl
Two minimal Tat translocases in Bacillus.
Molecular microbiology 2004;54(5):1319-25.
2004: Matti Sarvas; Colin R Harwood; Sierd Bron; Jan Maarten van Dijl
Post-translocational folding of secretory proteins in Gram-positive bacteria.
Biochimica et biophysica acta 2004;1694(1-3):311-27.
2004: Maarten L van Roosmalen; Nick Geukens; Jan D H Jongbloed; Harold Tjalsma; Jean-Yves François Dubois; Sierd Bron; Jan Maarten van Dijl; Jozef Anne
Type I signal peptidases of Gram-positive bacteria.
Biochimica et biophysica acta 2004;1694(1-3):279-97.
2004: Nathalie Campo; Harold Tjalsma; Girbe Buist; Dariusz Stepniak; Michel Meijer; Marten Veenhuis; Martin Westermann; Jörg P Müller; Sierd Bron; Jan Kok; Oscar P Kuipers; Jan D H Jongbloed
Subcellular sites for bacterial protein export.
Molecular microbiology 2004;53(6):1583-99.
2004: Harold Tjalsma; Haike Antelmann; Jan D H Jongbloed; Peter G Braun; Elise Darmon; Ronald Dorenbos; Jean-Yves François Dubois; Helga Westers; Geeske Zanen; Wim J Quax; Oscar P Kuipers; Sierd Bron; Michael Hecker; Jan Maarten van Dijl
Proteomics of protein secretion by Bacillus subtilis: separating the "secrets" of the secretome.
Microbiology and molecular biology reviews : MMBR 2004;68(2):207-33.
2004: Cordula Lindner; Reindert Nijland; Mariska van Hartskamp; Sierd Bron; Leendert W Hamoen; Oscar P Kuipers
Differential expression of two paralogous genes of Bacillus subtilis encoding single-stranded DNA binding protein.
Journal of bacteriology 2004;186(4):1097-105.
2004: Helga Westers; Elise Darmon; Geeske Zanen; Jan-Willem Veening; Oscar P Kuipers; Sierd Bron; Wim J Quax; Jan Maarten van Dijl
The Bacillus secretion stress response is an indicator for alpha-amylase production levels.
Letters in applied microbiology 2004;39(1):65-73.
2004: Harold Tjalsma; Emmo J Koetje; Rense Kiewiet; Oscar P Kuipers; M Kolkman; J van der Laan; R Daskin; E Ferrari; Sierd Bron
Engineering of quorum-sensing systems for improved production of alkaline protease by Bacillus subtilis.
Journal of applied microbiology 2004;96(3):569-78.
2003: Helga Westers; Ronald Dorenbos; Jan Maarten van Dijl; Jorrit Kabel; Tony Flanagan; Kevin M Devine; Florence Jude; Simone J Seror; Aaron C Beekman; Elise Darmon; Caroline Eschevins; Anne de Jong; Sierd Bron; Oscar P Kuipers; Alessandra M Albertini; Haike Antelmann; Michael Hecker; Nicola Zamboni; Uwe Sauer; Claude Bruand; Dusko S Ehrlich; Juan C Alonso; Margarita Salas; Wim J Quax
Genome engineering reveals large dispensable regions in Bacillus subtilis.
Molecular biology and evolution 2003;20(12):2076-90.
2003: Haike Antelmann; Elise Darmon; David Noone; Jan-Willem Veening; Helga Westers; Sierd Bron; Oscar P Kuipers; Kevin M Devine; Michael Hecker; Jan Maarten van Dijl
The extracellular proteome of Bacillus subtilis under secretion stress conditions.
Molecular microbiology 2003;49(1):143-56.
2003: Harold Tjalsma; Sierd Bron; Jan Maarten van Dijl
Complementary impact of paralogous Oxa1-like proteins of Bacillus subtilis on post-translocational stages in protein secretion.
The Journal of biological chemistry 2003;278(18):15622-32.
2003: Siger Holsappel; EIu Gagarina; EU Poluéktova; V Z Hezametdinova; M S Gel'fand; AA Prozorov; Sierd Bron
[The structure of the transposable genetic element ISBsu2 in the cryptic plasmid p1516 from a soil Bacillus subtilis strain and the presence of homologues of this element in the chromosomes of various Bacillus subtilis strains].
Mikrobiologiia 2003;72(1):70-5.
2003: Emmo J Koetje; Amra Hajdo-Milasinovic; Rense Kiewiet; Sierd Bron; Harold Tjalsma
A plasmid-borne Rap-Phr system of Bacillus subtilis can mediate cell-density controlled production of extracellular proteases.
Microbiology (Reading, England) 2003;149(Pt 1):19-28.
2002: EU Poluéktova; Siger Holsappel; EIu Gagarina; Sierd Bron; AA Prozorov
[The ISBsu2 mobile element is present in a plasmid of a soil strain and in the chromosomes of several other strains of Bacillus subtilis].
Genetika 2002;38(12):1719-22.
2002: Jan D H Jongbloed; Haike Antelmann; Michael Hecker; Reindert Nijland; Sierd Bron; Ulla Airaksinen; Frens Pries; Wim J Quax; Jan Maarten van Dijl; Peter G Braun
Selective contribution of the twin-arginine translocation pathway to protein secretion in Bacillus subtilis.
The Journal of biological chemistry 2002;277(46):44068-78.
2002: Elise Darmon; David Noone; Anne Masson; Sierd Bron; Oscar P Kuipers; Kevin M Devine; Jan Maarten van Dijl
A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis.
Journal of bacteriology 2002;184(20):5661-71.
2002: Jan Maarten van Dijl; Peter G Braun; Colin Robinson; Wim J Quax; Haike Antelmann; Michael Hecker; Jörg Müller; Harold Tjalsma; Sierd Bron; Jan D H Jongbloed
Functional genomic analysis of the Bacillus subtilis Tat pathway for protein secretion.
Journal of biotechnology 2002;98(2-3):243-54.
2002: EU Poluektova; Siger Holsappel; E Yu Gagarina; M S Gelfand; Sierd Bron; AA Prozorov
The presence of the transposable element ISBsu2 from a cryptic plasmid in chromosomes of some Bacillus subtilis strains.
Doklady. Biochemistry and biophysics 2002;386():275-7.
2002: Ronald Dorenbos; Torsten Stein; Jorrit Kabel; Claude Bruand; Albert Bolhuis; Sierd Bron; Wim J Quax; Jan Maarten van Dijl
Thiol-disulfide oxidoreductases are essential for the production of the lantibiotic sublancin 168.
The Journal of biological chemistry 2002;277(19):16682-8.
2002: Rob Meima; Caroline Eschevins; Sabine Fillinger; Albert Bolhuis; Leendert W Hamoen; Ronald Dorenbos; Wim J Quax; Jan Maarten van Dijl; Roberta Provvedi; Inês Chen; David Dubnau; Sierd Bron
The bdbDC operon of Bacillus subtilis encodes thiol-disulfide oxidoreductases required for competence development.
The Journal of biological chemistry 2002;277(9):6994-7001.
2001: Hanne-Leena Hyyryläinen; Albert Bolhuis; Elise Darmon; L Muukkonen; P Koski; Marika Vitikainen; Matti Sarvas; Zoltán Prágai; Sierd Bron; Jan Maarten van Dijl; Vesa P Kontinen
A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress.
Molecular microbiology 2001;41(5):1159-72.
2001: Haike Antelmann; Harold Tjalsma; Birgit Voigt; S Ohlmeier; Sierd Bron; Jan Maarten van Dijl; Michael Hecker
A proteomic view on genome-based signal peptide predictions.
Genome research 2001;11(9):1484-502.
2001: Nick Geukens; Elke Lammertyn; Lieve Van Mellaert; S Schacht; Kristien Schaerlaekens; Víctor Parro; Sierd Bron; Yves Engelborghs; Rafael P Mellado; Jozef Anne
Membrane topology of the Streptomyces lividans type I signal peptidases.
Journal of bacteriology 2001;183(16):4752-60.
2001: Maarten L van Roosmalen; Jan D H Jongbloed; Jean-Yves François Dubois; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Distinction between major and minor Bacillus signal peptidases based on phylogenetic and structural criteria.
The Journal of biological chemistry 2001;276(27):25230-5.
2001: Bidyut K Mohanty; Dirk Bussiere; T Sahoo; K S Pai; W J Meijer; Sierd Bron; Deepak Bastia
Structural and functional analysis of a bipolar replication terminus. Implications for the origin of polarity of fork arrest.
The Journal of biological chemistry 2001;276(16):13160-8.
2001: Maarten L van Roosmalen; Jan D H Jongbloed; A de Jonf; J van Eerden; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Detergent-independent in vitro activity of a truncated Bacillus signal peptidase.
Microbiology (Reading, England) 2001;147(Pt 4):909-17.
2001: Zoltán Prágai; Caroline Eschevins; Sierd Bron; Colin R Harwood
Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline phosphatases.
Journal of bacteriology 2001;183(8):2505-15.
2000: Jan D H Jongbloed; U Martin; Haike Antelmann; Michael Hecker; Harold Tjalsma; Gerard Venema; Sierd Bron; Jan Maarten van Dijl; J Müller
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
The Journal of biological chemistry 2000;275(52):41350-7.
2000: Maarten L van Roosmalen; Jan D H Jongbloed; Anneke Kuipers; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
A truncated soluble Bacillus signal peptidase produced in Escherichia coli is subject to self-cleavage at its active site.
Journal of bacteriology 2000;182(20):5765-70.
2000: Harold Tjalsma; Albert Bolhuis; Jan D H Jongbloed; Sierd Bron; Jan Maarten van Dijl
Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome.
Microbiology and molecular biology reviews : MMBR 2000;64(3):515-47.
2000: Harold Tjalsma; A G Stover; A Driks; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Conserved serine and histidine residues are critical for activity of the ER-type signal peptidase SipW of Bacillus subtilis.
The Journal of biological chemistry 2000;275(33):25102-8.
2000: Albert Bolhuis; Emmo J Koetje; Jean-Yves François Dubois; J Vehmaanperä; G Venema; Sierd Bron; Jan Maarten van Dijl
Did the mitochondrial processing peptidase evolve from a eubacterial regulator of gene expression?
Molecular biology and evolution 2000;17(1):198-201.
2000: Jörg P Müller; Sierd Bron; G Venema; J M van Dijl
Chaperone-like activities of the CsaA protein of Bacillus subtilis.
Microbiology (Reading, England) 2000;146 ( Pt 1)():77-88.
1999: Harold Tjalsma; Geeske Zanen; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
The potential active site of the lipoprotein-specific (type II) signal peptidase of Bacillus subtilis.
The Journal of biological chemistry 1999;274(40):28191-7.
1999: Albert Bolhuis; A Matzen; Hanne-Leena Hyyryläinen; Vesa P Kontinen; Rob Meima; J Chapuis; Gerard Venema; Sierd Bron; Roland Freudl; Jan Maarten van Dijl
Signal peptide peptidase- and ClpP-like proteins of Bacillus subtilis required for efficient translocation and processing of secretory proteins.
The Journal of biological chemistry 1999;274(35):24585-92.
1999: Albert Bolhuis; Gerard Venema; Wim J Quax; Sierd Bron; Jan Maarten van Dijl
Functional analysis of paralogous thiol-disulfide oxidoreductases in Bacillus subtilis.
The Journal of biological chemistry 1999;274(35):24531-8.
1999: Oscar P Kuipers; Anne de Jong; Siger Holsappel; Sierd Bron; Jan Kok; Leendert W Hamoen
DNA-microarrays and food-biotechnology.
Antonie van Leeuwenhoek 1999;76(1-4):353-5.
1999: Albert Bolhuis; Harold Tjalsma; H E Smith; Anne de Jong; Rob Meima; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Evaluation of bottlenecks in the late stages of protein secretion in Bacillus subtilis.
Applied and environmental microbiology 1999;65(7):2934-41.
1999: Albert Bolhuis; Harold Tjalsma; Keith Stephenson; Colin R Harwood; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Different mechanisms for thermal inactivation of Bacillus subtilis signal peptidase mutants.
The Journal of biological chemistry 1999;274(22):15865-8.
1999: Harold Tjalsma; J van den Dolder; W J Meijer; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
The plasmid-encoded signal peptidase SipP can functionally replace the major signal peptidases SipS and SipT of Bacillus subtilis.
Journal of bacteriology 1999;181(8):2448-54.
1999: Harold Tjalsma; Vesa P Kontinen; Zoltán Prágai; H Wu; Rob Meima; Gerard Venema; Sierd Bron; Matti Sarvas; Jan Maarten van Dijl
The role of lipoprotein processing by signal peptidase II in the Gram-positive eubacterium bacillus subtilis. Signal peptidase II is required for the efficient secretion of alpha-amylase, a non-lipoprotein.
The Journal of biological chemistry 1999;274(3):1698-707.
1998: Sierd Bron; Albert Bolhuis; Harold Tjalsma; Siger Holsappel; Gerard Venema; Jan Maarten van Dijl
Protein secretion and possible roles for multiple signal peptidases for precursor processing in bacilli.
Journal of biotechnology 1998;64(1):3-13.
1998: Albert Bolhuis; Kees Broekhuizen; Alexei Sorokin; Maarten L van Roosmalen; Gerard Venema; Sierd Bron; Wim J Quax; Jan Maarten van Dijl
SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins.
The Journal of biological chemistry 1998;273(33):21217-24.
1998: Harold Tjalsma; Albert Bolhuis; Maarten L van Roosmalen; Thomas Wiegert; W Schumann; Kees Broekhuizen; Wim J Quax; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidases.
Genes & development 1998;12(15):2318-31.
1998: Rob Meima; Gert Jan Haan; Gerard Venema; Sierd Bron; S de Jong
Sequence specificity of illegitimate plasmid recombination in Bacillus subtilis: possible recognition sites for DNA topoisomerase I.
Nucleic acids research 1998;26(10):2366-73.
1998: MA Noback; Siger Holsappel; Rense Kiewiet; Peter Terpstra; R Wambutt; Holger Wedler; Gerard Venema; Sierd Bron
The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene.
Microbiology (Reading, England) 1998;144 ( Pt 4)():859-75.
1998: W J Meijer; G B Wisman; Peter Terpstra; P B Thorsted; C M Thomas; Siger Holsappel; Gerard Venema; Sierd Bron
Rolling-circle plasmids from Bacillus subtilis: complete nucleotide sequences and analyses of genes of pTA1015, pTA1040, pTA1050 and pTA1060, and comparisons with related plasmids from gram-positive bacteria.
FEMS microbiology reviews 1998;21(4):337-68.
1998: S Schacht; Lieve Van Mellaert; Elke Lammertyn; Harold Tjalsma; J M van Dijl; Sierd Bron; Jozef Anne
The Sip(Sli) gene of Streptomyces lividans TK24 specifies an unusual signal peptidase with a putative C-terminal transmembrane anchor.
DNA sequence : the journal of DNA sequencing and mapping 1998;9(2):79-88.
1997: Harold Tjalsma; MA Noback; Sierd Bron; Gerard Venema; K Yamane; Jan Maarten van Dijl
Bacillus subtilis contains four closely related type I signal peptidases with overlapping substrate specificities. Constitutive and temporally controlled expression of different sip genes.
The Journal of biological chemistry 1997;272(41):25983-92.
1997: Zoltán Prágai; Harold Tjalsma; Albert Bolhuis; Jan Maarten van Dijl; Gerard Venema; Sierd Bron
The signal peptidase II (Isp) gene of Bacillus subtilis.
Microbiology (Reading, England) 1997;143 ( Pt 4)():1327-33.
1997: Rob Meima; BJ Haijema; H Dijkstra; Gert Jan Haan; Gerard Venema; Sierd Bron
Role of enzymes of homologous recombination in illegitimate plasmid recombination in Bacillus subtilis.
Journal of bacteriology 1997;179(4):1219-29.
1996: M A Noback; Peter Terpstra; Siger Holsappel; Gerard Venema; Sierd Bron
A 22 kb DNA sequence in the cspB-glpPFKD region at 75 degrees on the Bacillus subtilis chromosome.
Microbiology (Reading, England) 1996;142 ( Pt 11)():3021-6.
1996: Albert Bolhuis; Alexei Sorokin; V Azevedo; S Dusko Ehrlich; P G Braun; A de Jong; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Bacillus subtilis can modulate its capacity and specificity for protein secretion through temporally controlled expression of the sipS gene for signal peptidase I.
Molecular microbiology 1996;22(4):605-18.
1996: C Cordes; Rob Meima; B Twiest; B Kazemier; Gerard Venema; Jan Maarten van Dijl; Sierd Bron
The expression of a plasmid-specified exported protein causes structural plasmid instability in Bacillus subtilis.
Journal of bacteriology 1996;178(17):5235-42.
1996: W J Meijer; M Smith; R G Wake; A L de Boer; Gerard Venema; Sierd Bron
Identification and characterization of a novel type of replication terminator with bidirectional activity on the Bacillus subtilis theta plasmid pLS20.
Molecular microbiology 1996;19(6):1295-306.
1996: Rob Meima; Gerard Venema; Sierd Bron
A positive selection vector for the analysis of structural plasmid instability in Bacillus subtilis.
Plasmid 1996;35(1):14-30.
1995: Jos Seegers; A C Zhao; W J Meijer; S A Khan; Gerard Venema; Sierd Bron
Structural and functional analysis of the single-strand origin of replication from the lactococcal plasmid pWV01.
Molecular & general genetics : MGG 1995;249(1):43-50.
1995: Rob Meima; B J Haijema; Gerard Venema; Sierd Bron
Overproduction of the ATP-dependent nuclease AddAB improves the structural stability of a model plasmid system in Bacillus subtilis.
Molecular & general genetics : MGG 1995;248(4):391-8.
1995: W J Meijer; A J de Boer; S van Tongeren; Gerard Venema; Sierd Bron
Characterization of the replication region of the Bacillus subtilis plasmid pLS20: a novel type of replicon.
Nucleic acids research 1995;23(16):3214-23.
1995: W J Meijer; A de Jong; G Bea; A Wisman; Harold Tjalsma; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
The endogenous Bacillus subtilis (natto) plasmids pTA1015 and pTA1040 contain signal peptidase-encoding genes: identification of a new structural module on cryptic plasmids.
Molecular microbiology 1995;17(4):621-31.
1995: W J Meijer; D van der Lelie; Gerard Venema; Sierd Bron
Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in Lactococcus lactis.
Plasmid 1995;33(2):91-9.
1995: W J Meijer; D van der Lelie; Gerard Venema; Sierd Bron
Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in different Bacillus subtilis strains.
Plasmid 1995;33(2):79-89.
1995: W J Meijer; Gerard Venema; Sierd Bron
Characterization of single strand origins of cryptic rolling-circle plasmids from Bacillus subtilis.
Nucleic acids research 1995;23(4):612-9.
1995: Jan Maarten van Dijl; A de Jong; Gerard Venema; Sierd Bron
Identification of the potential active site of the signal peptidase SipS of Bacillus subtilis. Structural and functional similarities with LexA-like proteases.
The Journal of biological chemistry 1995;270(8):3611-8.
1995: Jos Seegers; C M Franke; R Kiewiet; Gerard Venema; Sierd Bron
Use of continuous culture for the selection of plasmids with improved segregational stability.
Plasmid 1995;33(1):71-7.
1994: Jos Seegers; Sierd Bron; C M Franke; Gerard Venema; R Kiewiet
The majority of lactococcal plasmids carry a highly related replicon.
Microbiology (Reading, England) 1994;140 ( Pt 6)():1291-300.
1993: J Vehmaanperä; A Görner; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
In vitro assay for the Bacillus subtilis signal peptidase SipS: systems for efficient in vitro transcription-translation and processing of precursors of secreted proteins.
FEMS microbiology letters 1993;114(2):207-14.
1993: R Kiewiet; Sierd Bron; K de Jonge; Gerard Venema; Jos Seegers
Theta replication of the lactococcal plasmid pWVO2.
Molecular microbiology 1993;10(2):319-27.
1993: R Kiewiet; Jan Kok; J F Seegers; Gerard Venema; Sierd Bron
The Mode of Replication Is a Major Factor in Segregational Plasmid Instability in Lactococcus lactis.
Applied and environmental microbiology 1993;59(2):358-64.
1992: G Perez-Martinez; Jan Kok; Gerard Venema; Jan Maarten van Dijl; H Smith; Sierd Bron
Protein export elements from Lactococcus lactis.
Molecular & general genetics : MGG 1992;234(3):401-11.
1992: Jan Maarten van Dijl; A de Jong; J Vehmaanperä; Gerard Venema; Sierd Bron
Signal peptidase I of Bacillus subtilis: patterns of conserved amino acids in prokaryotic and eukaryotic type I signal peptidases.
The EMBO journal 1992;11(8):2819-28.
1992: L Oskam; Gerard Venema; Sierd Bron
Plasmid pTB913 derivatives are segregationally stable in Bacillus subtilis at elevated temperatures.
Plasmid 1992;28(1):70-9.
1992: L Oskam; Gerard Venema; Sierd Bron
Plasmid maintenance in Bacillus stearothermophilus is strain-dependent.
FEMS microbiology letters 1992;72(3):203-8.
1992: L Oskam; D J Hillenga; Gerard Venema; Sierd Bron
The integrated state of the rolling-circle plasmid pTB913 in the composite Bacillus plasmid pTB19.
Molecular & general genetics : MGG 1992;233(3):462-8.
1991: Jan Maarten van Dijl; A de Jong; H Smith; Sierd Bron; Gerard Venema
Non-functional expression of Escherichia coli signal peptidase I in Bacillus subtilis.
Journal of general microbiology 1991;137(9):2073-83.
1991: Sierd Bron; W Meijer; Siger Holsappel; Peter Haima
Plasmid instability and molecular cloning in Bacillus subtilis.
Research in microbiology 1991;142(7-8):875-83.
1991: L Oskam; D J Hillenga; Gerard Venema; Sierd Bron
The large Bacillus plasmid pTB19 contains two integrated rolling-circle plasmids carrying mobilization functions.
Plasmid 1991;26(1):30-9.
1991: Jan Maarten van Dijl; A de Jong; H Smith; Sierd Bron; Gerard Venema
Lack of specific hybridization between the lep genes of Salmonella typhimurium and Bacillus licheniformis.
FEMS microbiology letters 1991;65(3):345-51.
1991: Kees Leenhouts; B Tolner; Sierd Bron; Jan Kok; Gerard Venema; Jos Seegers
Nucleotide sequence and characterization of the broad-host-range lactococcal plasmid pWVO1.
Plasmid 1991;26(1):55-66.
1991: Jan Maarten van Dijl; A de Jong; H Smith; Sierd Bron; Gerard Venema
Signal peptidase I overproduction results in increased efficiencies of export and maturation of hybrid secretory proteins in Escherichia coli.
Molecular & general genetics : MGG 1991;227(1):40-8.
1991: Sierd Bron; Siger Holsappel; Gerard Venema; B P Peeters
Plasmid deletion formation between short direct repeats in Bacillus subtilis is stimulated by single-stranded rolling-circle replication intermediates.
Molecular & general genetics : MGG 1991;226(1-2):88-96.
1990: Jan Maarten van Dijl; R van den Bergh; T Reversma; H Smith; Sierd Bron; Gerard Venema
Molecular cloning of the Salmonella typhimurium lep gene in Escherichia coli.
Molecular & general genetics : MGG 1990;223(2):233-40.
1990: B P Peeters; Sierd Bron; S Dusko Ehrlich
Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences.
The EMBO journal 1990;9(9):3023.
1990: Peter Haima; Sierd Bron; Gerard Venema
Novel plasmid marker rescue transformation system for molecular cloning in Bacillus subtilis enabling direct selection of recombinants.
Molecular & general genetics : MGG 1990;223(2):185-91.
1990: Peter Haima; D van Sinderen; Sierd Bron; Gerard Venema
An improved beta-galactosidase alpha-complementation system for molecular cloning in Bacillus subtilis.
Gene 1990;93(1):41-7.
1990: Ad Peijnenburg; Gerard Venema; Sierd Bron
Translational coupling in a penP-lacZ gene fusion in Bacillus subtilis and Escherichia coli: use of AUA as a restart codon.
Molecular & general genetics : MGG 1990;221(2):267-72.
1990: Peter Haima; D van Sinderen; H Schotting; Sierd Bron; Gerard Venema
Development of a beta-galactosidase alpha-complementation system for molecular cloning in Bacillus subtilis.
Gene 1990;86(1):63-9.
1990: D van der Lelie; H A Wösten; Sierd Bron; L Oskam; Gerard Venema
Conjugal mobilization of streptococcal plasmid pMV158 between strains of Lactococcus lactis subsp. lactis.
Journal of bacteriology 1990;172(1):47-52.
1989: D Brunier; B P Peeters; Sierd Bron; S Dusko Ehrlich
Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences.
The EMBO journal 1989;8(10):3127-33.
1989: D van der Lelie; Sierd Bron; Gerard Venema; L Oskam
Similarity of minus origins of replication and flanking open reading frames of plasmids pUB110, pTB913 and pMV158.
Nucleic acids research 1989;17(18):7283-94.
1989: Ad Peijnenburg; P V Breed; Sierd Bron; Gerard Venema
Plasmid deletion formation in recE4 and addB72 mutants of Bacillus subtilis.
Plasmid 1989;21(3):205-15.
1988: H Smith; A de Jong; Sierd Bron; Gerard Venema
Characterization of signal-sequence-coding regions selected from the Bacillus subtilis chromosome.
Gene 1988;70(2):351-61.
1988: Jan Maarten van Dijl; H Smith; Sierd Bron; Gerard Venema
Synthesis and processing of Escherichia coli TEM-beta-lactamase and Bacillus licheniformis alpha-amylase in E. coli: the role of signal peptidase I.
Molecular & general genetics : MGG 1988;214(1):55-61.
1988: Ad Peijnenburg; Sierd Bron; Gerard Venema
Plasmid deletion formation in Bacillus subtilis.
Plasmid 1988;20(1):23-32.
1988: B P Peeters; J H de Boer; Sierd Bron; Gerard Venema
Structural plasmid instability in Bacillus subtilis: effect of direct and inverted repeats.
Molecular & general genetics : MGG 1988;212(3):450-8.
1988: Sierd Bron; E Luxen; P Swart
Instability of recombinant pUB110 plasmids in Bacillus subtilis: plasmid-encoded stability function and effects of DNA inserts.
Plasmid 1988;19(3):231-41.
1988: Sierd Bron; L Jannière; S D Ehrlich
Restriction and modification in Bacillus subtilis Marburg 168: target sites and effects on plasmid transformation.
Molecular & general genetics : MGG 1988;211(1):186-9.
1987: Peter Haima; Sierd Bron; Gerard Venema
The effect of restriction on shotgun cloning and plasmid stability in Bacillus subtilis Marburg.
Molecular & general genetics : MGG 1987;209(2):335-42.
1987: Sierd Bron; P Bosma; M van Belkum; E Luxen
Stability function in the Bacillus subtilis plasmid pTA 1060.
Plasmid 1987;18(1):8-15.
1985: Sierd Bron; E Luxen
Segregational instability of pUB110-derived recombinant plasmids in Bacillus subtilis.
Plasmid 1985;14(3):235-44.
1984: Sierd Bron; E Luxen; G Venema
Restriction of hemimethylated DNA by the Bacillus subtilis R system.
Molecular & general genetics : MGG 1984;195(1-2):370-3.
1983: Sierd Bron; E Luxen; G Venema
Resistance of bacteriophage H1 to restriction and modification by Bacillus subtilis R.
Journal of virology 1983;46(3):703-8.
1982: Sierd Bron; E Luxen; G Venema
Restriction and modification in Bacillus subtilis: effects on transfection under marker rescue conditions.
Journal of virology 1982;42(2):357-64.
1980: Sierd Bron; E Luxen; T A Trautner
Restriction and modification in B. subtilis: the role of homology between donor and recipient DNA in transformation and transfection.
Molecular & general genetics : MGG 1980;179(1):111-7.
1980: Sierd Bron; E Luxen; G Venema; T A Trautner
Restriction and modification in B. subtilis: effects on transformation and transfection with native and single-stranded DNA.
Molecular & general genetics : MGG 1980;179(1):103-10.