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Jürgen Zapf

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Elisabeth Eppler; Antje Caelers; Natallia Shved; Gyulin Hwang; Azizur M Rahman; Norman Maclean; Jürgen Zapf; Manfred Reinecke
Insulin-like growth factor I (IGF-I) in a growth-enhanced transgenic (GH-overexpressing) bony fish, the tilapia (Oreochromis niloticus): indication for a higher impact of autocrine/paracrine than of endocrine IGF-I.
Michael A Nauck; Manfred Reinecke; Aurel Perren; Jan Frystyk; Giorgi Berishvili; Cornelia Zwimpfer; Anja M Figge; Allan Flyvbjerg; Paul G Lankisch; Werner Blum; Günter Klöppel; Wolff Schmiegel; Jürgen Zapf
Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastasizing large-cell carcinoma of the lung.
Christoph Schmid; Cornelia Zwimpfer; Michael Brändle; Pierre-Alexandre Krayenbühl; Jürgen Zapf; Peter Wiesli
Effect of thyroxine replacement on serum IGF-I, IGFBP-3 and the acid-labile subunit in patients with hypothyroidism and hypopituitarism.

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2007: Elisabeth Eppler; Antje Caelers; Natallia Shved; Gyulin Hwang; Azizur M Rahman; Norman Maclean; Jürgen Zapf; Manfred Reinecke
Insulin-like growth factor I (IGF-I) in a growth-enhanced transgenic (GH-overexpressing) bony fish, the tilapia (Oreochromis niloticus): indication for a higher impact of autocrine/paracrine than of endocrine IGF-I.
Transgenic research 2007;16(4):479-89.
2007: Michael A Nauck; Manfred Reinecke; Aurel Perren; Jan Frystyk; Giorgi Berishvili; Cornelia Zwimpfer; Anja M Figge; Allan Flyvbjerg; Paul G Lankisch; Werner Blum; Günter Klöppel; Wolff Schmiegel; Jürgen Zapf
Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastasizing large-cell carcinoma of the lung.
The Journal of clinical endocrinology and metabolism 2007;92(5):1600-5.
2006: Christoph Schmid; Cornelia Zwimpfer; Michael Brändle; Pierre-Alexandre Krayenbühl; Jürgen Zapf; Peter Wiesli
Effect of thyroxine replacement on serum IGF-I, IGFBP-3 and the acid-labile subunit in patients with hypothyroidism and hypopituitarism.
Clinical endocrinology 2006;65(6):706-11.
2006: Peter Wiesli; Cornelia Zwimpfer; Jürgen Zapf; Christoph Schmid
Pregnancy-induced changes in insulin-like growth factor I (IGF-I), insulin-like growth factor binding protein 3 (IGFBP-3), and acid-labile subunit (ALS) in patients with growth hormone (GH) deficiency and excess.
Acta obstetricia et gynecologica Scandinavica 2006;85(8):900-5.
2005: Christoph Schmid; Tarcisio Bianda; Cornelia Zwimpfer; Jürgen Zapf; Peter Wiesli
Changes in insulin sensitivity induced by short-term growth hormone (GH) and insulin-like growth factor I (IGF-I) treatment in GH-deficient adults are not associated with changes in adiponectin levels.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2005;15(4):300-3.
2005: Tanja Jevdjovic; Caroline Maake; Cornelia Zwimpfer; Gunthild Krey; Elisabeth Eppler; Jürgen Zapf; Manfred Reinecke
The effect of hypophysectomy on pancreatic islet hormone and insulin-like growth factor I content and mRNA expression in rat.
Histochemistry and cell biology 2005;123(2):179-88.
2005: Peter Wiesli; René Bernays; Michael Brändle; Cornelia Zwimpfer; Heidi Seiler; Jürgen Zapf; Giatgen A Spinas; Christoph Schmid
Effect of pituitary surgery in patients with acromegaly on adiponectin serum concentrations and alanine aminotransferase activity.
Clinica chimica acta; international journal of clinical chemistry 2005;352(1-2):175-81.
2004: Tanja Jevdjovic; Caroline Maake; Elisabeth Eppler; Evangelos Zoidis; Manfred Reinecke; Jürgen Zapf
Effects of insulin--like growth factor-I treatment on the endocrine pancreas of hypophysectomized rats: comparison with growth hormone replacement.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(2):223-31.
2004: Peter Wiesli; Michael Brändle; Thomas Pfammatter; Jürgen Zapf; Giatgen A Spinas; Christoph Schmid
Insulin determination by specific and unspecific immunoassays in patients with insulinoma evaluated by the arterial stimulation and venous sampling test.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(1):123-6.
2004: Evangelos Zoidis; Claudia Ghirlanda-Keller; Martina Gosteli-Peter; Jürgen Zapf; Christoph Schmid
Regulation of phosphate (Pi) transport and NaPi-III transporter (Pit-1) mRNA in rat osteoblasts.
The Journal of endocrinology 2004;181(3):531-40.
2004: Peter Wiesli; Michael Brändle; Jürgen Zapf; Heidi Seiler; Cornelia Zwimpfer; Giatgen A Spinas; Christoph Schmid
Assessment of hyperinsulinaemia at the termination of the prolonged fast.
Clinica chimica acta; international journal of clinical chemistry 2004;342(1-2):227-31.
2004: Christoph Schmid; Peter Wiesli; René Bernays; Konrad Bloch; Jürgen Zapf; Cornelia Zwimpfer; Claudia Ghirlanda; Michael Brändle
Decrease in sE-selectin after pituitary surgery in patients with acromegaly.
Clinical chemistry 2004;50(3):650-2.
2004: Christoph Schmid; Michael Brändle; Cornelia Zwimpfer; Jürgen Zapf; Peter Wiesli
Effect of thyroxine replacement on creatinine, insulin-like growth factor 1, acid-labile subunit, and vascular endothelial growth factor.
Clinical chemistry 2004;50(1):228-31.
2003: Lorenz Meinel; Evangelos Zoidis; Jürgen Zapf; Paul O Hassa; Michael Hottiger; Joerg A Auer; Rebecca Schneider; Bruno Gander; Vera Luginbuehl; Regula Bettschart-Wolfisberger; Oscar E Illi; Hans P Merkle; Brigitte von Rechenberg
Localized insulin-like growth factor I delivery to enhance new bone formation.
Bone 2003;33(4):660-72.
2002: Jürgen Zapf; Martina Gosteli-Peter; Gisbert Weckbecker; Ernst B Hunziker; Manfred Reinecke
The somatostatin analog octreotide inhibits GH-stimulated, but not IGF-I-stimulated, bone growth in hypophysectomized rats.
Endocrinology 2002;143(8):2944-52.
2002: Elisabeth Eppler; Jürgen Zapf; N Bailer; Ursula G Falkmer; Sture Falkmer; Manfred Reinecke
IGF-I in human breast cancer: low differentiation stage is associated with decreased IGF-I content.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(6):813-21.
2002: Evangelos Zoidis; Martina Gosteli-Peter; Claudia Ghirlanda-Keller; Lorenz Meinel; Jürgen Zapf; Christoph Schmid
IGF-I and GH stimulate Phex mRNA expression in lungs and bones and 1,25-dihydroxyvitamin D(3) production in hypophysectomized rats.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(1):97-105.
2001: K T Bostedt; Christoph Schmid; Claudia Ghirlanda-Keller; Robert A Olie; K H Winterhalter; Jürgen Zapf
Insulin-like growth factor (IGF) I down-regulates type 1 IGF receptor (IGF 1R) and reduces the IGF I response in A549 non-small-cell lung cancer and Saos-2/B-10 osteoblastic osteosarcoma cells.
Experimental cell research 2001;271(2):368-77.
2001: Christoph Schmid; Claudia Ghirlanda-Keller; Jürgen Zapf
Effects of IGF-I and -II, IGF binding protein-3 (IGFBP-3), and transforming growth factor-beta (TGF-beta) on growth and apoptosis of human osteosarcoma Saos-2/B-10 cells: lack of IGF-independent IGFBP-3 effects.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(2):213-21.
2001: Lorenz Meinel; O E Illi; Jürgen Zapf; M Malfanti; H Peter Merkle; Bruno Gander
Stabilizing insulin-like growth factor-I in poly(D,L-lactide-co-glycolide) microspheres.
Journal of controlled release : official journal of the Controlled Release Society 2001;70(1-2):193-202.
2000: Evangelos Zoidis; Jürgen Zapf; Christoph Schmid
Phex cDNA cloning from rat bone and studies on phex mRNA expression: tissue-specificity, age-dependency, and regulation by insulin-like growth factor (IGF) I in vivo.
Molecular and cellular endocrinology 2000;168(1-2):41-51.
2000: Manfred Reinecke; Annette C Schmid; B Heyberger-Meyer; E B Hunziker; Jürgen Zapf
Effect of growth hormone and insulin-like growth factor I (IGF-I) on the expression of IGF-I messenger ribonucleic acid and peptide in rat tibial growth plate and articular chondrocytes in vivo.
Endocrinology 2000;141(8):2847-53.
2000: Jürgen Zapf; Marc Y Donath; C Schmid
[Spectrum of effectiveness of insulin-like growth factors (IGF)].
Schweizerische medizinische Wochenschrift 2000;130(6):190-5.
1999: Christoph Schmid; C Keller; Martina Gosteli-Peter; Jürgen Zapf
Mitogenic and antiapoptotic effects of insulin-like growth factor binding protein-6 in the human osteoblastic osteosarcoma cell line Saos-2/B-10.
Biochemical and biophysical research communications 1999;263(3):786-9.
1999: Marc Y Donath; Jürgen Zapf
Insulin-like growth factor I: an attractive option for chronic heart failure?
Drugs & aging 1999;15(4):251-4.
1999: Tarcisio Bianda; Jürgen Zapf; ER Froesch; Christoph Schmid
Insulin-like growth factor-I lowers fasting and postprandial triglyceride levels without affecting chylomicron clearance in healthy men.
Journal of internal medicine 1999;245(5):455-62.
1999: M Böni-Schnetzler; C Hauri; Jürgen Zapf
Leptin is suppressed during infusion of recombinant human insulin-like growth factor I (rhIGF I) in normal rats.
Diabetologia 1999;42(2):160-6.
1998: Marc Y Donath; Gabor Sütsch; XW Yan; B Piva; HP Brunner; Y Glatz; Jürgen Zapf; F Follath; ER Froesch; W Kiowski
Acute cardiovascular effects of insulin-like growth factor I in patients with chronic heart failure.
The Journal of clinical endocrinology and metabolism 1998;83(9):3177-83.
1998: Marc Y Donath; W Zierhut; Martina Gosteli-Peter; C Hauri; ER Froesch; Jürgen Zapf
Effects of IGF-I on cardiac growth and expression of mRNAs coding for cardiac proteins after induction of heart hypertrophy in the rat.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(1):109-17.
1998: Jürgen Zapf
Growth promotion by insulin-like growth factor I in hypophysectomized and diabetic rats.
Molecular and cellular endocrinology 1998;140(1-2):143-9.
1998: Christoph Schmid; C Keller; I Schläpfer; CM Veldman; Jürgen Zapf
Calcium and insulin-like growth factor I stimulation of sodium-dependent phosphate transport and proliferation of cultured rat osteoblasts.
Biochemical and biophysical research communications 1998;245(1):220-5.
1998: Marc Y Donath; ER Froesch; Jürgen Zapf
Insulin-like growth factor I and cardiac performance in heart failure.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl B():167-70.
1997: S Schmitt; Q Ren-Qiu; Toni Torresani; M Doebeli; Jürgen Zapf; Eugen J Schoenle
High molecular weight forms of IGF-II ('big-IGF-II') released by Wilms' tumor cells.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(4):396-401.
1997: Marc Y Donath; Martina Gosteli-Peter; C Hauri; ER Froesch; Jürgen Zapf
Insulin-like growth factor-I stimulates myofibrillar genes and modulates atrial natriuretic factor mRNA in rat heart.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(3):309-15.
1997: Jürgen Zapf
Total and free IGF serum levels.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(2):146-7.
1996: Christoph Schmid; I Schläpfer; Martina Gosteli-Peter; ER Froesch; Jürgen Zapf
Effects and fate of human IGF-binding protein-5 in rat osteoblast cultures.
The American journal of physiology 1996;271(6 Pt 1):E1029-35.
1996: Martina Gosteli-Peter; BA Harder; Hans M Eppenberger; Jürgen Zapf; Marcus C Schaub
Triiodothyronine induces over-expression of alpha-smooth muscle actin, restricts myofibrillar expansion and is permissive for the action of basic fibroblast growth factor and insulin-like growth factor I in adult rat cardiomyocytes.
The Journal of clinical investigation 1996;98(8):1737-44.
1996: ER Froesch; Mehboob A Hussain; Christoph Schmid; Jürgen Zapf
Insulin-like growth factor I: physiology, metabolic effects and clinical uses.
Diabetes/metabolism reviews 1996;12(3):195-215.
1996: Christoph Schmid; I Schläpfer; Martina Gosteli-Peter; C Hauri; ER Froesch; Jürgen Zapf
1 alpha,25-dihydroxyvitamin D3 increases IGF binding protein-5 expression in cultured osteoblasts.
FEBS letters 1996;392(1):21-4.
1996: M Böni-Schnetzler; Martina Gosteli-Peter; W Moritz; ER Froesch; Jürgen Zapf
Reduced ob mRNA in hypophysectomised rats is not restored by growth hormone (GH), but further suppressed by exogenously administered insulin-like growth factor (IGF) I.
Biochemical and biophysical research communications 1996;225(1):296-301.
1996: Martina Gosteli-Peter; Christoph Schmid; Jürgen Zapf
Triiodothyronine increases glucose transporter isotype 4 mRNA expression, glucose transport, and glycogen synthesis in adult rat cardiomyocytes in long-term culture.
Biochemical and biophysical research communications 1996;221(3):521-4.
1995: Christoph Schmid; I Schläpfer; A Keller; M Waldvogel; ER Froesch; Jürgen Zapf
Effects of insulin-like growth factor (IGF) binding proteins (BPs) -3 and -6 on DNA synthesis of rat osteoblasts: further evidence for a role of auto-/paracrine IGF I but not IGF II in stimulating osteoblast growth.
Biochemical and biophysical research communications 1995;212(1):242-8.
1995: Jürgen Zapf
Physiological role of the insulin-like growth factor binding proteins.
European journal of endocrinology / European Federation of Endocrine Societies 1995;132(6):645-54.
1995: Cheryl A Conover; S K Durham; Jürgen Zapf; F R Masiarz; M C Kiefer
Cleavage analysis of insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis and expression of protease-resistant IGF-binding protein-4 mutants.
The Journal of biological chemistry 1995;270(9):4395-400.
1995: Christoph Schmid; I Schläpfer; Martina Gosteli-Peter; ER Froesch; Jürgen Zapf
Expression, effects, and fate of IGFBP-5 are different in normal and malignant osteoblastic cells.
Progress in growth factor research 1995;6(2-4):167-73.
1995: Jürgen Zapf; C Hauri; E Futo; Mehboob A Hussain; J Rutishauser; C A Maack; ER Froesch
Intravenously injected insulin-like growth factor (IGF) I/IGF binding protein-3 complex exerts insulin-like effects in hypophysectomized, but not in normal rats.
The Journal of clinical investigation 1995;95(1):179-86.
1994: Martina Gosteli-Peter; K H Winterhalter; Christoph Schmid; ER Froesch; Jürgen Zapf
Expression and regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein messenger ribonucleic acid levels in tissues of hypophysectomized rats infused with IGF-I and growth hormone.
Endocrinology 1994;135(6):2558-67.
1994: Mehboob A Hussain; O Schmitz; A Mengel; Y Glatz; J S Christiansen; Jürgen Zapf; ER Froesch
Comparison of the effects of growth hormone and insulin-like growth factor I on substrate oxidation and on insulin sensitivity in growth hormone-deficient humans.
The Journal of clinical investigation 1994;94(3):1126-33.
1994: Christoph Schmid; I Schläpfer; M Peter; M Böni-Schnetzler; J Schwander; Jürgen Zapf; ER Froesch
Growth hormone and parathyroid hormone stimulate IGFBP-3 in rat osteoblasts.
The American journal of physiology 1994;267(2 Pt 1):E226-33.
1994: Marc Y Donath; Jürgen Zapf; M Eppenberger-Eberhardt; ER Froesch; Hans M Eppenberger
Insulin-like growth factor I stimulates myofibril development and decreases smooth muscle alpha-actin of adult cardiomyocytes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1686-90.
1994: Jürgen Zapf
Role of insulin-like growth factor II and IGF binding proteins in extrapancreatic tumor hypoglycemia.
Hormone research 1994;42(1-2):20-6.
1993: M A Peter; K H Winterhalter; M Böni-Schnetzler; ER Froesch; Jürgen Zapf
Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by growth hormone in rat white adipose tissue.
Endocrinology 1993;133(6):2624-31.
1993: Jürgen Zapf
Role of insulin-like growth factor (IGF) II and IGF binding proteins in extrapancreatic tumour hypoglycaemia.
Journal of internal medicine 1993;234(6):543-52.
1993: J Rutishauser; Christoph Schmid; C Hauri; ER Froesch; Jürgen Zapf
Growth hormone, but not insulin-like growth factor I, induces a serum protease activity for insulin-like growth factor binding protein-3 in hypophysectomized rats in vivo.
FEBS letters 1993;334(1):23-6.
1993: Mehboob A Hussain; O Schmitz; A Mengel; A Keller; J S Christiansen; Jürgen Zapf; ER Froesch
Insulin-like growth factor I stimulates lipid oxidation, reduces protein oxidation, and enhances insulin sensitivity in humans.
The Journal of clinical investigation 1993;92(5):2249-56.
1993: U Eriksson; G Duc; ER Froesch; Jürgen Zapf
Insulin-like growth factors (IGF) I and II and IGF binding proteins (IGFBPs) in human colostrum/transitory milk during the first week postpartum: comparison with neonatal and maternal serum.
Biochemical and biophysical research communications 1993;196(1):267-73.
1993: Christoph Schmid; I Schläpfer; M Waldvogel; M Peter; Jürgen Zapf; ER Froesch
Production of IGFBP-3 by connective tissue and endothelial cells.
Growth regulation 1993;3(1):65-7.
1993: M C Kiefer; Christoph Schmid; M Waldvogel; I Schläpfer; E Futo; F R Masiarz; K Green; P J Barr; Jürgen Zapf
Recombinant human insulin-like growth factor binding proteins 4, 5, and 6: biological and physiochemical characterization.
Growth regulation 1993;3(1):56-9.
1993: Cheryl A Conover; M C Kiefer; Jürgen Zapf
Posttranslational regulation of insulin-like growth factor binding protein-4 in normal and transformed human fibroblasts. Insulin-like growth factor dependence and biological studies.
The Journal of clinical investigation 1993;91(3):1129-37.
1992: Jürgen Zapf; E Futo; M Peter; ER Froesch
Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia?
The Journal of clinical investigation 1992;90(6):2574-84.
1992: Christoph Schmid; I Schläpfer; M Waldvogel; Jürgen Zapf; ER Froesch
Prostaglandin E2 stimulates synthesis of insulin-like growth factor binding protein-3 in rat bone cells in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(10):1157-63.
1992: M C Kiefer; Christoph Schmid; M Waldvogel; I Schläpfer; E Futo; F R Masiarz; K Green; P J Barr; Jürgen Zapf
Characterization of recombinant human insulin-like growth factor binding proteins 4, 5, and 6 produced in yeast.
The Journal of biological chemistry 1992;267(18):12692-9.
1992: Christoph Schmid; I Schläpfer; M Waldvogel; Peter Meier; J Schwander; M Böni-Schnetzler; Jürgen Zapf; ER Froesch
Differential regulation of insulin-like growth factor binding protein (IGFBP)-2 mRNA in liver and bone cells by insulin and retinoic acid in vitro.
FEBS letters 1992;303(2-3):205-9.
1992: Christoph Schmid; I Schläpfer; E Futo; M Waldvogel; J Schwander; Jürgen Zapf; ER Froesch
Triiodothyronine (T3) stimulates insulin-like growth factor (IGF)-1 and IGF binding protein (IGFBP)-2 production by rat osteoblasts in vitro.
Acta endocrinologica 1992;126(5):467-73.
1991: Christoph Schmid; J Rutishauser; I Schläpfer; ER Froesch; Jürgen Zapf
Intact but not truncated insulin-like growth factor binding protein-3 (IGFBP-3) blocks IGF I-induced stimulation of osteoblasts: control of IGF signalling to bone cells by IGFBP-3-specific proteolysis?
Biochemical and biophysical research communications 1991;179(1):579-85.
1991: M C Kiefer; F R Masiarz; D M Bauer; Jürgen Zapf
Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum.
The Journal of biological chemistry 1991;266(14):9043-9.
1991: M C Kiefer; R S Ioh; D M Bauer; Jürgen Zapf
Molecular cloning of a new human insulin-like growth factor binding protein.
Biochemical and biophysical research communications 1991;176(1):219-25.
1991: H P Guler; K Wettstein; W Schurr; Jürgen Zapf; ER Froesch
Recombinant human insulin-like growth factor I: effects in normal subjects and implications for use in patients.
Advances in experimental medicine and biology 1991;293():97-104.
1990: Jürgen Zapf; M Kiefer; J Merryweather; F Musiarz; D Bauer; W Born; J A Fischer; ER Froesch
Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia.
The Journal of biological chemistry 1990;265(25):14892-8.
1990: M Böni-Schnetzler; Christoph Schmid; J L Mary; B Zimmerli; Peter Meier; Jürgen Zapf; J Schwander; ER Froesch
Insulin regulates the expression of the insulin-like growth factor binding protein 2 mRNA in rat hepatocytes.
Molecular endocrinology (Baltimore, Md.) 1990;4(9):1320-6.
1990: Jürgen Zapf; Christoph Schmid; H P Guler; M Waldvogel; C Hauri; E Futo; P Hossenlopp; Michel Binoux; ER Froesch
Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia.
The Journal of clinical investigation 1990;86(3):952-61.
1990: K Binz; P Joller; P Froesch; H Binz; Jürgen Zapf; ER Froesch
Repopulation of the atrophied thymus in diabetic rats by insulin-like growth factor I.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3690-4.
1990: H P Guler; Christoph Schmid; Jürgen Zapf; ER Froesch
Effects of insulin-like growth factor I in man.
Acta paediatrica Scandinavica. Supplement 1990;367():52-4.
1989: S Keller; Jürgen Zapf
Effect of insulin on glucose transporter distribution in white fat cells from hypophysectomized rats.
FEBS letters 1989;259(1):189-93.
1989: H P Guler; Jürgen Zapf; Christoph Schmid; ER Froesch
Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production rates.
Acta endocrinologica 1989;121(6):753-8.
1989: K Binz; Jürgen Zapf; ER Froesch
The role of insulin-like growth factor I in growth of diabetic rats.
Acta endocrinologica 1989;121(5):628-32.
1989: H P Guler; K Binz; E Eigenmann; S Jäggi; D Zimmermann; Jürgen Zapf; ER Froesch
Small stature and insulin-like growth factors: prolonged treatment of mini-poodles with recombinant human insulin-like growth factor I.
Acta endocrinologica 1989;121(3):456-64.
1989: S Keller; Christoph Schmid; Jürgen Zapf; ER Froesch
Inhibition of insulin degradation by insulin-like growth factors I and II in human hepatoma (HepG2) cells.
Acta endocrinologica 1989;121(2):279-85.
1989: Jürgen Zapf; C Hauri; M Waldvogel; E Futo; H Häsler; K Binz; H P Guler; Christoph Schmid; ER Froesch
Recombinant human insulin-like growth factor I induces its own specific carrier protein in hypophysectomized and diabetic rats.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3813-7.
1989: H P Guler; Christoph Schmid; Jürgen Zapf; ER Froesch
Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2868-72.
1988: Jürgen Zapf; W Born; J Y Chang; P James; ER Froesch; J A Fischer
Isolation and NH2-terminal amino acid sequences of rat serum carrier proteins for insulin-like growth factors.
Biochemical and biophysical research communications 1988;156(3):1187-94.
1988: H P Guler; Jürgen Zapf; E Scheiwiller; ER Froesch
Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4889-93.
1988: P D Zenobi; H P Guler; Jürgen Zapf; ER Froesch
Insulin-like growth factors in the Göttinger miniature-pig.
Acta endocrinologica 1988;117(3):343-52.
1986: Jürgen Zapf; C Hauri; M Waldvogel; ER Froesch
Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats.
The Journal of clinical investigation 1986;77(6):1768-75.