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Carlos Zarate

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Dawn F Ionescu; Daniel C Mathews; Mark J Niciu; Erica M Richards; Carlos A Zarate
Neurobiology of anxious depression: a review.
Wallace C Duncan; Fabio Ferrarelli; Nadia S Hejazi; Husseini K Manji; Brady A Riedner; Simone Sarasso; Jessica Selter; Giulio Tononi; Peixiong Yuan; Nancy Brutsche; Carlos A Zarate
Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder.
Wallace C Duncan; Simone Sarasso; Jessica Selter; Nancy Brutsche; Carlos A Zarate
Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder.

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All Publications

2013: Dawn F Ionescu; Daniel C Mathews; Mark J Niciu; Erica M Richards; Carlos A Zarate
Neurobiology of anxious depression: a review.
Depression and anxiety 2013;30(4):374-85.
2013: Wallace C Duncan; Fabio Ferrarelli; Nadia S Hejazi; Husseini K Manji; Brady A Riedner; Simone Sarasso; Jessica Selter; Giulio Tononi; Peixiong Yuan; Nancy Brutsche; Carlos A Zarate
Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2013;16(2):301-11.
2013: Wallace C Duncan; Simone Sarasso; Jessica Selter; Nancy Brutsche; Carlos A Zarate
Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder.
Journal of affective disorders 2013;145(1):115-9.
2013: Márcio Gerhardt Soeiro-de-Souza; Carlos A Zarate; Kalil T Chaim; Wagner F Gattaz; Ricardo Alberto Moreno; Maria Concepción Garcia Otaduy; Giacomo Salvadore; Rodrigo Machado-Vieira
Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013;38(3):468-75.
2013: Rodrigo Machado-Vieira; Getulio Marca; Marcio G Soeiro-de-Souza; Joao V Busnello; Wagner F Gattaz; Ioline D Henter; David A Luckenbaugh; Carlos A Zarate
Early improvement with lithium in classic mania and its association with later response.
Journal of affective disorders 2013;144(1-2):160-4.
2012: David A Luckenbaugh; Craig A Marquardt; Daniel Mathews; Nancy Brutsche; Christy Cassarly; Jose Franco-Chaves; Lobna Ibrahim; Carlos A Zarate
Family history of alcohol dependence and antidepressant response to an N-methyl-D-aspartate antagonist in bipolar depression.
Bipolar disorders 2012;14(8):880-7.
2012: Gonzalo Laje; Níall Lally; Daniel Mathews; Francis J McMahon; Gerard Sanacora; Arthur Simen; Nirmala Akula; Nancy Brutsche; Anat Chemerinski; Benjamin Kelmendi; Carlos A Zarate
Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.
Biological psychiatry 2012;72(11):e27-8.
2012: Paolo Zanotti Fregonara; Carlos A Zarate; Yi Zhang; Sami S Zoghbi; Wayne C Drevets; Masahiro Fujita; Christina S Hines; Jeih-San Liow; ALAN MALLINGER; Victor W Pike; Robert B Innis
Population-based input function and image-derived input function for [¹¹C](R)-rolipram PET imaging: methodology, validation and application to the study of major depressive disorder.
NeuroImage 2012;63(3):1532-41.
2012: Masahiro Fujita; Christina S Hines; Robert B Innis; Jeih-San Liow; ALAN MALLINGER; Victor W Pike; Leah P Dickstein; Wayne C Drevets; Yi Zhang; Sami S Zoghbi; Carlos A Zarate
Downregulation of brain phosphodiesterase type IV measured with 11C-(R)-rolipram positron emission tomography in major depressive disorder.
Biological psychiatry 2012;72(7):548-54.
2012: Brian Cornwell; Maura L Furey; Christian Grillon; Craig A Marquardt; Giacomo Salvadore; Nancy E Brutsche; Carlos A Zarate
Synaptic potentiation is critical for rapid antidepressant response to ketamine in treatment-resistant major depression.
Biological psychiatry 2012;72(7):555-61.
2012: Giacomo Salvadore; Jun Shen; Jan Willem van der Veen; Jacqueline Baumann; Wayne C Drevets; Lobna A Ibrahim; David A Luckenbaugh; Rodrigo Machado-Vieira; Stefano Marenco; Yan Zhang; Carlos A Zarate
An investigation of amino-acid neurotransmitters as potential predictors of clinical improvement to ketamine in depression.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012;15(8):1063-72.
2012: Oz Malkesman; Husseini K Manji; Kazu Nakazawa; Gregory Rompala; Tyson Tragon; Gang Wang; W Scott Young; Carlos A Zarate; Daniel R Austin; Zhenzhong Cui; Anahita B Hamidi; Guang Chen
Acute D-serine treatment produces antidepressant-like effects in rodents.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012;15(8):1135-48.
2012: Carlos A Zarate; Nancy Brutsche; Gonzalo Laje; David A Luckenbaugh; Ruin Moaddel; Anuradha Ramamoorthy; Swarajya L Vattem Venkata; irving william wainer
Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression.
Biological psychiatry 2012;72(4):331-8.
2012: Lobna Ibrahim; Libby Jolkovsky; David Luckenbaugh; William Z Potter; Nancy Brutsche; William Joseph Herring; Nancy Diaz Granados; Carlos A Zarate
A Randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder.
Journal of clinical psychopharmacology 2012;32(4):551-7.
2012: Xiaochen Zhao; Carlos A Zarate; Nancy E Brutsche; Lobna Ibrahim; David Luckenbaugh; Donald E Mager; Ruin Moaddel; Swarajya Lakshmi Vattem Venkata; irving william wainer
Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.
British journal of clinical pharmacology 2012;74(2):304-14.
2012: Daniel C Mathews; Ioline D Henter; Carlos A Zarate
Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date.
Drugs 2012;72(10):1313-33.
2012: Carlos A Zarate; Craig A Marquardt; Jessica Selter; Nancy E Brutsche; A Cravchik; Nancy Diazgranados; Jose Franco-Chaves; Lobna Ibrahim; Victoria Liberty; David Luckenbaugh
Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial.
Biological psychiatry 2012;71(11):939-46.
2012: Lobna Ibrahim; Phillip Kronstein; David Luckenbaugh; Husseini K Manji; Ruin Moaddel; Irving Wainer; Nancy Brutsche; Nancy Diazgranados; Jose Franco-Chaves; Ioline D Henter; Carlos A Zarate
Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012;37(6):1526-33.
2012: Maura L Furey; Elana M Hoffman; David Luckenbaugh; Allison C Nugent; Andrew M Speer; Wayne C Drevets; Erica Frankel; Carlos A Zarate
Baseline mood-state measures as predictors of antidepressant response to scopolamine.
Psychiatry research 2012;196(1):62-7.
2011: Lobna Ibrahim; David Luckenbaugh; Rodrigo Machado-Vieira; Peixiong Yuan; Wallace Duncan; Carlos A Zarate
Rapid antidepressant changes with sleep deprivation in major depressive disorder are associated with changes in vascular endothelial growth factor (VEGF): a pilot study.
Brain research bulletin 2011;86(1-2):129-33.
2011: Lobna Ibrahim; Nancy Diazgranados; David Luckenbaugh; Rodrigo Machado-Vieira; Jacqueline Baumann; ALAN MALLINGER; Carlos A Zarate
Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression.
Progress in neuro-psychopharmacology & biological psychiatry 2011;35(4):1155-9.
2011: Linda Mah; Carlos A Zarate; Allison C Nugent; Jaskaran B Singh; Husseini K Manji; Wayne C Drevets
Neural mechanisms of antidepressant efficacy of the dopamine receptor agonist pramipexole in treatment of bipolar depression.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2011;14(4):545-51.
2011: Rodrigo Machado-Vieira; Natalia B Pivovarova; Ruslan I Stanika; Peixiong Yuan; Yun Wang; Rulun Zhou; Carlos A Zarate; Wayne C Drevets; Christine A Brantner; Amber Baum; Gonzalo Laje; Francis McMajon; Guang Chen; Jing Du; Husseini K Manji; S Brian Andrews
The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder.
Biological psychiatry 2011;69(4):344-52.
2011: Jonathan B Savitz; Allison Nugent; Wendy Bogers; Jonathan P Roiser; Earle E Bain; Alexander Neumeister; Carlos A Zarate; Husseini K Manji; Dara M Cannon; Sean Marrett; Fritz Henn; Dennis S Charney; Wayne C Drevets
Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study.
Biological psychiatry 2011;69(4):336-43.
2011: Giacomo Salvadore; Allison Nugent; Herve Lemaitre; David Luckenbaugh; Ruth Tinsley; Dara M Cannon; Alexander Neumeister; Carlos A Zarate; Wayne C Drevets
Prefrontal cortical abnormalities in currently depressed versus currently remitted patients with major depressive disorder.
NeuroImage 2011;54(4):2643-51.
2010: Nancy DiazGranados; Lobna A Ibrahim; Nancy E Brutsche; Rezvan Ameli; Ioline D Henter; David Luckenbaugh; Rodrigo Machado-Vieira; Carlos A Zarate
Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.
The Journal of clinical psychiatry 2010;71(12):1605-11.
2010: Giacomo Salvadore; Jorge A Quiroz; Rodrigo Machado-Vieira; Ioline D Henter; Husseini K Manji; Carlos A Zarate
The neurobiology of the switch process in bipolar disorder: a review.
The Journal of clinical psychiatry 2010;71(11):1488-501.
2010: Carlos A Zarate; Rodrigo Machado-Vieira; Ioline D Henter; Lobna Ibrahim; Nancy Diazgranados; Giacomo Salvadore
Glutamatergic modulators: the future of treating mood disorders?
Harvard review of psychiatry 2010;18(5):293-303.
2010: Giacomo Salvadore; Carlos I Viale; David Luckenbaugh; Vanessa C Zanatto; Luis V Portela; Diogo O Souza; Carlos A Zarate; Rodrigo Machado-Vieira
Increased uric acid levels in drug-naïve subjects with bipolar disorder during a first manic episode.
Progress in neuro-psychopharmacology & biological psychiatry 2010;34(6):819-21.
2010: Brian R Cornwell; Giacomo Salvadore; Veronica Colon-Rosario; David R Latov; Tom Holroyd; Frederick W Carver; Richard Coppola; Husseini K Manji; Carlos A Zarate; Christian Grillon
Abnormal hippocampal functioning and impaired spatial navigation in depressed individuals: evidence from whole-head magnetoencephalography.
The American journal of psychiatry 2010;167(7):836-44.
2010: Giacomo Salvadore; Brian Cornwell; Fabio Sambataro; David Latov; Veronica Colon-Rosario; Frederick Carver; Tom Holroyd; Nancy DiazGranados; Rodrigo Machado-Vieira; Christian Grillon; Wayne C Drevets; Carlos A Zarate
Anterior cingulate desynchronization and functional connectivity with the amygdala during a working memory task predict rapid antidepressant response to ketamine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(7):1415-22.
2010: Jonathan Savitz; Allison Nugent; Wendy Bogers; Alice Liu; Rebecca Sills; David Luckenbaugh; Earle E Bain; Joseph L Price; Carlos A Zarate; Husseini K Manji; Dara M Cannon; Sean Marrett; Dennis S Charney; Wayne C Drevets
Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication.
NeuroImage 2010;49(4):2966-76.
2010: Rodrigo Machado-Vieira; Giacomo Salvadore; Nancy DiazGranados; Lobna Ibrahim; David Latov; Cristina Wheeler-Castillo; Jacqueline Baumann; Ioline D Henter; Carlos A Zarate
New therapeutic targets for mood disorders.
TheScientificWorldJournal 2010;10():713-26.
2009: Rodrigo Machado-Vieira; Peixiong Yuan; Nancy Brutsche; Nancy DiazGranados; David Luckenbaugh; Husseini K Manji; Carlos A Zarate
Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist.
The Journal of clinical psychiatry 2009;70(12):1662-6.
2009: Giacomo Salvadore; Allison C Nugent; Guang Chen; Nirmala Akula; Peixiong Yuan; Dara M Cannon; Carlos A Zarate; Francis McMajon; Husseini K Manji; Wayne C Drevets
Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans.
Biological psychiatry 2009;66(8):804-7.
2009: Rodrigo Machado-Vieira; Husseini K Manji; Carlos A Zarate
The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2009;15(5):525-39.
2009: Rodrigo Machado-Vieira; Giacomo Salvadore; Nancy Diazgranados; Carlos A Zarate
Ketamine and the next generation of antidepressants with a rapid onset of action.
Pharmacology & therapeutics 2009;123(2):143-50.
2009: Rodrigo Machado-Vieira; Husseini K Manji; Carlos A Zarate
The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis.
Bipolar disorders 2009;11 Suppl 2():92-109.
2009: Giacomo Salvadore; Brian Cornwell; Veronica Colon-Rosario; Richard Coppola; Christian Grillon; Carlos A Zarate; Husseini K Manji
Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine.
Biological psychiatry 2009;65(4):289-95.
2009: Laura E Phelps; Nancy Brutsche; Jazmin R Moral; David Luckenbaugh; Husseini K Manji; Carlos A Zarate
Family history of alcohol dependence and initial antidepressant response to an N-methyl-D-aspartate antagonist.
Biological psychiatry 2009;65(2):181-4.
2009: Carlos A Zarate; Husseini K Manji
Protein kinase C inhibitors: rationale for use and potential in the treatment of bipolar disorder.
CNS drugs 2009;23(7):569-82.
2009: Rodrigo Machado-Vieira; Giacomo Salvadore; Lobna A Ibrahim; Nancy Diaz-Granados; Carlos A Zarate
Targeting glutamatergic signaling for the development of novel therapeutics for mood disorders.
Current pharmaceutical design 2009;15(14):1595-611.
2008: Nancy DiazGranados; Carlos A Zarate
A review of the preclinical and clinical evidence for protein kinase C as a target for drug development for bipolar disorder.
Current psychiatry reports 2008;10(6):510-9.
2008: M Kathleen Holmes; Kristine Erickson; David Luckenbaugh; Wayne C Drevets; Earle E Bain; Dara M Cannon; Joseph Snow; Barbara J Sahakian; Husseini K Manji; Carlos A Zarate
A comparison of cognitive functioning in medicated and unmedicated subjects with bipolar depression.
Bipolar disorders 2008;10(7):806-15.
2008: Giacomo Salvadore; Wayne C Drevets; Ioline D Henter; Carlos A Zarate; Husseini K Manji
Early intervention in bipolar disorder, part II: therapeutics.
Early intervention in psychiatry 2008;2(3):136-46.
2008: Giacomo Salvadore; Wayne C Drevets; Ioline D Henter; Carlos A Zarate; Husseini K Manji
Early intervention in bipolar disorder, part I: clinical and imaging findings.
Early intervention in psychiatry 2008;2(3):122-35.
2008: Rodrigo Machado-Vieira; Jair C Soares; Diogo R Lara; David Luckenbaugh; João V Busnello; Getulio Marca; Angelo Cunha; Diogo O Souza; Carlos A Zarate; Flávio Kapczinski
A double-blind, randomized, placebo-controlled 4-week study on the efficacy and safety of the purinergic agents allopurinol and dipyridamole adjunctive to lithium in acute bipolar mania.
The Journal of clinical psychiatry 2008;69(8):1237-45.
2008: Rodrigo Machado-Vieira; Giacomo Salvadore; David Luckenbaugh; Husseini K Manji; Carlos A Zarate
Rapid onset of antidepressant action: a new paradigm in the research and treatment of major depressive disorder.
The Journal of clinical psychiatry 2008;69(6):946-58.
2008: Carlos A Zarate; Husseini K Manji
Bipolar disorder: candidate drug targets.
The Mount Sinai journal of medicine, New York 2008;75(3):226-47.
2008: Carlos A Zarate; Husseini K Manji
The role of AMPA receptor modulation in the treatment of neuropsychiatric diseases.
Experimental neurology 2008;211(1):7-10.
2008: Sungho Maeng; Carlos A Zarate; Jing Du; Robert Schloesser; Joseph McCammon; Guang Chen; Husseini K Manji
Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
Biological psychiatry 2008;63(4):349-52.
2008: Andrew Newberg; Lisa A Catapano; Carlos A Zarate; Husseini K Manji
Neurobiology of bipolar disorder.
Expert review of neurotherapeutics 2008;8(1):93-110.
2007: Sungho Maeng; Carlos A Zarate
The role of glutamate in mood disorders: results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects.
Current psychiatry reports 2007;9(6):467-74.
2007: Carlos A Zarate; Jaskaran B Singh; Paul J Carlson; Jorge A Quiroz; Libby Jolkovsky; David Luckenbaugh; Husseini K Manji
Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study.
Bipolar disorders 2007;9(6):561-70.
2007: Jing Du; Katsuji Suzuki; Yanling Wei; Yun Wang; Rayah Blumenthal; Zheng Chen; Cynthia Falke; Carlos A Zarate; Husseini K Manji
The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(4):793-802.
2007: Linda Mah; Carlos A Zarate; Jaskaran Singh; Yu-Fei Duan; David Luckenbaugh; Husseini K Manji; Wayne C Drevets
Regional cerebral glucose metabolic abnormalities in bipolar II depression.
Biological psychiatry 2007;61(6):765-75.
2007: Neda F Gould; M Kathleen Holmes; Bryan D Fantie; David Luckenbaugh; Daniel S Pine; Todd D Gould; Neil Burgess; Husseini K Manji; Carlos A Zarate
Performance on a virtual reality spatial memory navigation task in depressed patients.
The American journal of psychiatry 2007;164(3):516-9.
2006: Jaskaran B Singh; Carlos A Zarate
Pharmacological treatment of psychiatric comorbidity in bipolar disorder: a review of controlled trials.
Bipolar disorders 2006;8(6):696-709.
2006: Carlos A Zarate; Jaskaran B Singh; Paul J Carlson; Nancy E Brutsche; Rezvan Ameli; David Luckenbaugh; Dennis S Charney; Husseini K Manji
A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.
Archives of general psychiatry 2006;63(8):856-64.
2006: Carlos A Zarate; Jaskaran Singh; Husseini K Manji
Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder.
Biological psychiatry 2006;59(11):1006-20.
2006: Rulun Zhou; Carlos A Zarate; Husseini K Manji
Identification of molecular mechanisms underlying mood stabilization through genome-wide gene expression profiling.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2006;9(3):263-6.
2006: Allison Nugent; Michael P Milham; Earle E Bain; Linda Mah; Dara M Cannon; Sean Marrett; Carlos A Zarate; Daniel S Pine; Joseph L Price; Wayne C Drevets
Cortical abnormalities in bipolar disorder investigated with MRI and voxel-based morphometry.
NeuroImage 2006;30(2):485-97.
2006: Paul J Carlson; Jaskaran B Singh; Carlos A Zarate; Wayne C Drevets; Husseini K Manji
Neural circuitry and neuroplasticity in mood disorders: insights for novel therapeutic targets.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2006;3(1):22-41.
2006: Carlos A Zarate; Jaskaran B Singh; Jorge A Quiroz; Georgette De Jesus; Kirk K Denicoff; David Luckenbaugh; Husseini K Manji; Dennis S Charney
A double-blind, placebo-controlled study of memantine in the treatment of major depression.
The American journal of psychiatry 2006;163(1):153-5.
2005: Kristine Erickson; Wayne C Drevets; Luke Clark; Dara M Cannon; Earle E Bain; Carlos A Zarate; Dennis S Charney; Barbara J Sahakian
Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder.
The American journal of psychiatry 2005;162(11):2171-3.
2005: Carlos A Zarate; Jorge A Quiroz; Jaskaran B Singh; Kirk D Denicoff; Georgette De Jesus; David Luckenbaugh; Dennis S Charney; Husseini K Manji
An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression.
Biological psychiatry 2005;57(4):430-2.
2004: Jorge A Quiroz; Jaskaran Singh; Todd D Gould; Kirk D Denicoff; Carlos A Zarate; Husseini K Manji
Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology.
Molecular psychiatry 2004;9(8):756-76.
2004: Todd D Gould; Jorge A Quiroz; Jaskaran Singh; Carlos A Zarate; Husseini K Manji
Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers.
Molecular psychiatry 2004;9(8):734-55.
2004: Carlos A Zarate; Jennifer L Payne; Jaskaran Singh; Jorge A Quiroz; David Luckenbaugh; Kirk D Denicoff; Dennis S Charney; Husseini K Manji
Pramipexole for bipolar II depression: a placebo-controlled proof of concept study.
Biological psychiatry 2004;56(1):54-60.
2004: Jing Du; Neil A Gray; Jorge A Quiroz; Steven Szabo; Carlos A Zarate; Husseini K Manji
Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking.
Dialogues in clinical neuroscience 2004;6(2):143-55.
2004: Todd D Gould; Carlos A Zarate; Husseini K Manji
Glycogen synthase kinase-3: a target for novel bipolar disorder treatments.
The Journal of clinical psychiatry 2004;65(1):10-21.
2004: Carlos A Zarate; Jennifer L Payne; Jorge A Quiroz; Jonathan Sporn; Kirk K Denicoff; David Luckenbaugh; Dennis S Charney; Husseini K Manji
An open-label trial of riluzole in patients with treatment-resistant major depression.
The American journal of psychiatry 2004;161(1):171-4.
2003: Carlos A Zarate; Jing Du; Jorge A Quiroz; Neil A Gray; Kirk D Denicoff; Jaskaran Singh; Dennis S Charney; Husseini K Manji
Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system.
Annals of the New York Academy of Sciences 2003;1003():273-91.
2003: Husseini K Manji; Jorge A Quiroz; Jennifer L Payne; Jaskaran Singh; Barbara P Lopes; Jenilee S Viegas; Carlos A Zarate
The underlying neurobiology of bipolar disorder.
World psychiatry : official journal of the World Psychiatric Association (WPA) 2003;2(3):136-46.
2003: Carlos A Zarate; Jorge A Quiroz
Combination treatment in bipolar disorder: a review of controlled trials.
Bipolar disorders 2003;5(3):217-25.
2003: Husseini K Manji; Jorge A Quiroz; Jonathan Sporn; Jennifer L Payne; Kirk D Denicoff; Neil A Gray; Carlos A Zarate; Dennis S Charney
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression.
Biological psychiatry 2003;53(8):707-42.
2002: Jennifer L Payne; Jorge A Quiroz; Carlos A Zarate; Husseini K Manji
Timing is everything: does the robust upregulation of noradrenergically regulated plasticity genes underlie the rapid antidepressant effects of sleep deprivation?
Biological psychiatry 2002;52(10):921-6.
2002: Carlos A Zarate; Jorge Quiroz; Jennifer L Payne; Husseini K Manji
Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders.
Psychopharmacology bulletin 2002;36(4):35-83.
2001: Carlos A Zarate; M Tohen; K Fletcher
Cycling into depression from a first episode of mania: a case-comparison study.
The American journal of psychiatry 2001;158(9):1524-6.