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Antonio Zarzuelo

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TOP 3
N Garrido-Mesa; Antonio Zarzuelo; Julio Gálvez
Minocycline: far beyond an antibiotic.
Francesca Algieri; Oscar Bañuelos; Manuel Casares-Porcel; Natividad Garrido-Mesa; M Reyes González-Tejero; Joaquín Molero-Mesa; M Elena Rodriguez-Cabezas; Alba Rodriguez-Nogales; M Pilar Utrilla; Antonio Zarzuelo; Pedro Zorrilla; Julio Galvez
Intestinal anti-inflammatory activity of hydroalcoholic extracts of Phlomis purpurea L. and Phlomis lychnitis L. in the trinitrobenzenesulphonic acid model of rat colitis.
Borja Ocón; Mercedes Ortega-González; Fermin Sanchez de Medina; María Dolores Suárez; Antonio Zarzuelo; Andrea Anzola; Olga Martínez-Augustin
Active hexose-correlated compound and Bifidobacterium longum BB536 exert symbiotic effects in experimental colitis.

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All Publications

2013: N Garrido-Mesa; Antonio Zarzuelo; Julio Gálvez
Minocycline: far beyond an antibiotic.
British journal of pharmacology 2013;169(2):337-52.
2013: Francesca Algieri; Oscar Bañuelos; Manuel Casares-Porcel; Natividad Garrido-Mesa; M Reyes González-Tejero; Joaquín Molero-Mesa; M Elena Rodriguez-Cabezas; Alba Rodriguez-Nogales; M Pilar Utrilla; Antonio Zarzuelo; Pedro Zorrilla; Julio Galvez
Intestinal anti-inflammatory activity of hydroalcoholic extracts of Phlomis purpurea L. and Phlomis lychnitis L. in the trinitrobenzenesulphonic acid model of rat colitis.
Journal of ethnopharmacology 2013;146(3):750-9.
2013: Borja Ocón; Mercedes Ortega-González; Fermin Sanchez de Medina; María Dolores Suárez; Antonio Zarzuelo; Andrea Anzola; Olga Martínez-Augustin
Active hexose-correlated compound and Bifidobacterium longum BB536 exert symbiotic effects in experimental colitis.
European journal of nutrition 2013;52(2):457-66.
2013: Abdelali Daddaoua; Fermín Sánchez de Medina; Carlos J Aranda; Enrique Martínez-Plata; Borja Ocón; Mercedes Ortega-González; María D Suárez; Antonio Zarzuelo; Olga Martínez-Augustin
The nutritional supplement Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-κB/MAPK activation.
Food chemistry 2013;136(3-4):1288-95.
2013: Patricia Martínez-Moya; Pilar Requena; Isabel Romero-Calvo; María Dolores Suárez; Antonio Zarzuelo; Raquel González; Cristina Hernández-Chirlaque; José Juan G Marín; Olga Martínez-Augustin; Carlos J Aranda; Fermin Sanchez de Medina
Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis.
International immunopharmacology 2013;15(2):372-80.
2013: N Garrido-Mesa; Antonio Zarzuelo; Julio Gálvez
What is behind the non-antibiotic properties of minocycline?
Pharmacological research : the official journal of the Italian Pharmacological Society 2013;67(1):18-30.
2012: P Martínez-Moya; B Ocón; M Ortega-González; A Anzola; R González; C Hernández-Chirlaque; R López-Posadas; Olga Martínez-Augustin; María Dolores Suárez; Antonio Zarzuelo; Fermin Sanchez de Medina
Exogenous alkaline phosphatase treatment complements endogenous enzyme protection in colonic inflammation and reduces bacterial translocation in rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 2012;66(2):144-53.
2012: Elvira Bailón; Margarita Cueto-Sola; Julio Gálvez; Natividad Garrido-Mesa; Judith Rodríguez-Ruiz; Pilar Utrilla; Jordi Xaus; Antonio Zarzuelo; Mònica Comalada
A shorter and more specific oral sensitization-based experimental model of food allergy in mice.
Journal of immunological methods 2012;381(1-2):41-9.
2012: Belén Arribas; Elvira Bailón; Desirée Camuesco; Mònica Comalada; Natividad Garrido-Mesa; Laurens Kruidenier; Mónica Olivares; Laura Perán; M Elena Rodríguez-Cabezas; Ian R Sanderson; Jordi Xaus; Antonio Zarzuelo; Julio Gálvez
The immunomodulatory properties of viable Lactobacillus salivarius ssp. salivarius CECT5713 are not restricted to the large intestine.
European journal of nutrition 2012;51(3):365-74.
2011: Natividad Garrido-Mesa; M Elena Rodríguez-Cabezas; Pilar Utrilla; Antonio Zarzuelo; Pedro Zorrilla; Mònica Comalada; José Garrido-Mesa; Julio Gálvez
The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice.
Biochemical pharmacology 2011;82(12):1891-900.
2011: Elvira Bailón; Antonio Celada; Margarita Cueto-Sola; Julio Gálvez; Natividad Garrido-Mesa; Ana Nieto; Pilar Utrilla; Jordi Xaus; Antonio Zarzuelo; Mònica Comalada
DNFB-DNS hapten-induced colitis in mice should not be considered a model of inflammatory bowel disease.
Inflammatory bowel diseases 2011;17(10):2087-101.
2011: María José Zarzuelo; Elvira Bailón; Pilar Galindo; Julio Gálvez; Manuel Gómez-Guzmán; Rosario Jiménez; Rocío López-Sepúlveda; Ana Nieto; Francisco Pérez-Vizcaíno; Ana María Quintela; Isabel Rodríguez-Gómez; Miguel Romero; Manuel Sanchez; Juan Tamargo; Antonio Zarzuelo; Juan Duarte
Antihypertensive effects of peroxisome proliferator-activated receptor-β activation in spontaneously hypertensive rats.
Hypertension 2011;58(4):733-43.
2011: Isabel Romero-Calvo; María Dolores Suárez; Antonio Zarzuelo; Olga Martínez-Augustin; Cristina Mascaraque; Fermin Sanchez de Medina
Intestinal inflammation and the enterocyte transportome.
Biochemical Society transactions 2011;39(4):1096-101.
2011: R González; Isabel Ballester; R López-Posadas; M D Suárez; Antonio Zarzuelo; O Martínez-Augustin; F Sánchez de Medina
Effects of flavonoids and other polyphenols on inflammation.
Critical reviews in food science and nutrition 2011;51(4):331-62.
2011: Natividad Garrido-Mesa; Desirée Camuesco; Belén Arribas; Mònica Comalada; Elvira Bailón; Margarita Cueto-Sola; Pilar Utrilla; Ana Nieto; Antonio Zarzuelo; M Elena Rodríguez-Cabezas; Julio Gálvez
The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;63(4):308-19.
2011: Rocío López-Posadas; Raquel González; Isabel Ballester; Patricia Martínez-Moya; Isabel Romero-Calvo; María Dolores Suárez; Antonio Zarzuelo; Olga Martínez-Augustin; Fermin Sanchez de Medina
Tissue-nonspecific alkaline phosphatase is activated in enterocytes by oxidative stress via changes in glycosylation.
Inflammatory bowel diseases 2011;17(2):543-56.
2010: M Elena Rodríguez-Cabezas; Desirée Camuesco; Belén Arribas; Natividad Garrido-Mesa; Mònica Comalada; Elvira Bailón; Margarita Cueto-Sola; Pilar Utrilla; Eduardo Guerra-Hernández; Carlos Pérez-Roca; Julio Gálvez; Antonio Zarzuelo
The combination of fructooligosaccharides and resistant starch shows prebiotic additive effects in rats.
Clinical nutrition (Edinburgh, Scotland) 2010;29(6):832-9.
2010: Rocío López-Posadas; Pilar Requena; Raquel González; María Dolores Suárez; Antonio Zarzuelo; Fermin Sanchez de Medina; Olga Martínez-Augustin
Bovine glycomacropeptide has intestinal antiinflammatory effects in rats with dextran sulfate-induced colitis.
The Journal of nutrition 2010;140(11):2014-9.
2010: Elvira Bailón; Margarita Cueto-Sola; Pilar Utrilla; M Elena Rodríguez-Cabezas; Natividad Garrido-Mesa; Antonio Zarzuelo; Jordi Xaus; Julio Gálvez; Mònica Comalada
Butyrate in vitro immune-modulatory effects might be mediated through a proliferation-related induction of apoptosis.
Immunobiology 2010;215(11):863-73.
2010: Miguel Romero; Rosario Jiménez; Manuel Sanchez; Rocío López-Sepúlveda; Antonio Zarzuelo; Juan Tamargo; Francisco Pérez-Vizcaíno; Juan Duarte
Vascular superoxide production by endothelin-1 requires Src non-receptor protein tyrosine kinase and MAPK activation.
Atherosclerosis 2010;212(1):78-85.
2010: R López-Posadas; Isabel Ballester; C Mascaraque; María Dolores Suárez; Antonio Zarzuelo; Olga Martínez-Augustin; Fermin Sanchez de Medina
Flavonoids exert distinct modulatory actions on cyclooxygenase 2 and NF-kappaB in an intestinal epithelial cell line (IEC18).
British journal of pharmacology 2010;160(7):1714-26.
2010: Fermín Sánchez de Medina; Abdelali Daddaoua; Pilar Requena; Fermín Capitán-Cañadas; Antonio Zarzuelo; María Dolores Suárez; Olga Martínez-Augustin
New insights into the immunological effects of food bioactive peptides in animal models of intestinal inflammation.
The Proceedings of the Nutrition Society 2010;69(3):454-62.
2010: Isabel Romero-Calvo; Borja Ocón; Patricia Martínez-Moya; María Dolores Suárez; Antonio Zarzuelo; Olga Martínez-Augustin; Fermin Sanchez de Medina
Reversible Ponceau staining as a loading control alternative to actin in Western blots.
Analytical biochemistry 2010;401(2):318-20.
2010: Pilar Requena; Raquel González; Rocío López-Posadas; Ana Abadía-Molina; María Dolores Suárez; Antonio Zarzuelo; Fermin Sanchez de Medina; Olga Martínez-Augustin
The intestinal antiinflammatory agent glycomacropeptide has immunomodulatory actions on rat splenocytes.
Biochemical pharmacology 2010;79(12):1797-804.
2010: Belén Arribas; Elena Suárez-Pereira; Carmen Ortiz Mellet; José M García Fernández; Christoph Buttersack; M Elena Rodríguez-Cabezas; Natividad Garrido-Mesa; Elvira Bailon; Eduardo Guerra-Hernández; Antonio Zarzuelo; Julio Gálvez
Di-D-fructose dianhydride-enriched caramels: effect on colon microbiota, inflammation, and tissue damage in trinitrobenzenesulfonic acid-induced colitic rats.
Journal of agricultural and food chemistry 2010;58(10):6476-84.
2010: Olga Martínez-Augustin; Rocío López-Posadas; Raquel González; Isabel Ballester; María Dolores Suárez; Antonio Zarzuelo; Fermín Sánchez de Medina
It may not be intestinal, but tissue non-specific alkaline phosphatase.
Gut 2010;59(4):560; author reply 560.
2010: Milagros Galisteo; Rocío Morón; Leonor Rivera; Rosario Romero; Anna Anguera; Antonio Zarzuelo
Plantago ovata husks-supplemented diet ameliorates metabolic alterations in obese Zucker rats through activation of AMP-activated protein kinase. Comparative study with other dietary fibers.
Clinical nutrition (Edinburgh, Scotland) 2010;29(2):261-7.
2010: Miguel Romero; Rosario Jiménez; Belén Hurtado; Juan Manuel Moreno; Isabel Rodríguez-Gómez; Rocío López-Sepúlveda; Antonio Zarzuelo; Francisco Pérez-Vizcaino; Juan Tamargo; Félix Vargas; Juan Duarte
Lack of beneficial metabolic effects of quercetin in adult spontaneously hypertensive rats.
European journal of pharmacology 2010;627(1-3):242-50.
2010: Rosario Jiménez; Manuel Sanchez; María José Zarzuelo; Miguel Romero; Ana María Quintela; Rocío López-Sepúlveda; Pilar Galindo; Manuel Gómez-Guzmán; Jose Manuel Haro; Antonio Zarzuelo; Francisco Pérez-Vizcaíno; Juan Duarte
Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor beta agonists via the phosphatidyl-inositol-3 kinase-Akt pathway.
The Journal of pharmacology and experimental therapeutics 2010;332(2):554-61.
2009: Pilar Requena; Abdelali Daddaoua; Emilia Guadix; Antonio Zarzuelo; María Dolores Suárez; Fermín Sánchez de Medina; Olga Martínez-Augustin
Bovine glycomacropeptide induces cytokine production in human monocytes through the stimulation of the MAPK and the NF-kappaB signal transduction pathways.
British journal of pharmacology 2009;157(7):1232-40.
2009: B Arribas; M Elena Rodríguez-Cabezas; Desirée Camuesco; Mònica Comalada; Elvira Bailón; P Utrilla; Ana Nieto; Angel Concha; Antonio Zarzuelo; Julio Gálvez
A probiotic strain of Escherichia coli, Nissle 1917, given orally exerts local and systemic anti-inflammatory effects in lipopolysaccharide-induced sepsis in mice.
British journal of pharmacology 2009;157(6):1024-33.
2009: Olga Martínez-Augustin; Rocío López-Posadas; Raquel González; María Dolores Suárez; Antonio Zarzuelo; Fermin Sanchez de Medina
Genomic analysis of sulfasalazine effect in experimental colitis is consistent primarily with the modulation of NF-kappaB but not PPAR-gamma signaling.
Pharmacogenetics and genomics 2009;19(5):363-72.
2009: Leonor Rivera; Rocío Morón; Antonio Zarzuelo; Milagros Galisteo
Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats.
Biochemical pharmacology 2009;77(6):1053-63.
2009: Elvira Bailón; Juan Román; Isabel Ramis; Pedro Michelena; Dolors Balsa; Manuel Merlos; Antonio Zarzuelo; Julio Gálvez; Mònica Comalada
The new salicylate derivative UR-1505 modulates the Th2/humoral response in a dextran sodium sulphate model of colitis that resembles ulcerative colitis.
Journal of pharmacological sciences 2009;109(2):315-8.
2009: Belén Arribas; Maria Elena Rodríguez-Cabezas; Mònica Comalada; Elvira Bailón; Desirée Camuesco; Mónica Olivares; Jordi Xaus; Antonio Zarzuelo; Julio Gálvez
Evaluation of the preventative effects exerted by Lactobacillus fermentum in an experimental model of septic shock induced in mice.
The British journal of nutrition 2009;101(1):51-8.
2008: Leonor Rivera; Rocío Morón; Manuel Sanchez; Antonio Zarzuelo; Milagros Galisteo
Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats.
Obesity (Silver Spring, Md.) 2008;16(9):2081-7.
2008: Rocío López-Posadas; Isabel Ballester; Ana Clara Abadía-Molina; María Dolores Suárez; Antonio Zarzuelo; Olga Martínez-Augustin; Fermin Sanchez de Medina
Effect of flavonoids on rat splenocytes, a structure-activity relationship study.
Biochemical pharmacology 2008;76(4):495-506.
2008: Elvira Bailón; Mònica Comalada; Juan Román; Pedro Michelena; Isabel Ramis; Manuel Merlos; Ana Nieto; Angel Concha; Antonio Zarzuelo; Julio Gálvez
UR-1505, a salicylate able to selectively block T-cell activation, shows intestinal anti-inflammatory activity in the chronic phase of the DSS model of rat colitis.
Inflammatory bowel diseases 2008;14(7):888-97.
2008: P Requena; Abdelali Daddaoua; E Martínez-Plata; Mercedes González; Antonio Zarzuelo; María Dolores Suárez; Fermin Sanchez de Medina; Olga Martínez-Augustin
Bovine glycomacropeptide ameliorates experimental rat ileitis by mechanisms involving downregulation of interleukin 17.
British journal of pharmacology 2008;154(4):825-32.
2008: Rocío López-Sepúlveda; Rosario Jiménez; Miguel Romero; Maria José Zarzuelo; Manuel Sanchez; Manuel Gómez-Guzmán; Félix Vargas; Francisco O'Valle; Antonio Zarzuelo; Francisco Pérez-Vizcaíno; Juan Duarte
Wine polyphenols improve endothelial function in large vessels of female spontaneously hypertensive rats.
Hypertension 2008;51(4):1088-95.
2008: Milagros Galisteo; Juan Duarte; Antonio Zarzuelo
Effects of dietary fibers on disturbances clustered in the metabolic syndrome.
The Journal of nutritional biochemistry 2008;19(2):71-84.
2008: José M García Pinilla; Julio Gálvez; Fernando Cabrera Bueno; Manuel F Jiménez-Navarro; Juan J Gómez-Doblas; Milagros Galisteo; Desiré Camuesco; Carlos de Teresa Galván; Salvador Espinosa Caliani; Antonio Zarzuelo; Eduardo De Teresa Galván
Baseline glutathione peroxidase activity affects prognosis after acute coronary syndromes.
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 2008;35(3):262-7.
2008: Olga Martínez-Augustin; Manuel Merlos; Antonio Zarzuelo; María Dolores Suárez; Fermin Sanchez de Medina
Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis.
BMC genomics 2008;9():490.
2007: Elvira Bailón; Desirée Camuesco; Ana Nieto; Angel Concha; Alberto Fernández de Arriba; Juan Román; Isabel Ramis; Manuel Merlos; Antonio Zarzuelo; Julio Gálvez; Mònica Comalada
The intestinal anti-inflammatory effects of the novel agent UR-1505 in the TNBS model of rat colitis are mediated by T-lymphocyte inhibition.
Biochemical pharmacology 2007;74(10):1496-506.
2007: Laura Peran; Desirée Camuesco; Mònica Comalada; E Bailon; A Henriksson; Jordi Xaus; Antonio Zarzuelo; Julio Galvez
A comparative study of the preventative effects exerted by three probiotics, Bifidobacterium lactis, Lactobacillus casei and Lactobacillus acidophilus, in the TNBS model of rat colitis.
Journal of applied microbiology 2007;103(4):836-44.
2007: Rocío Vera; Rosario Jiménez; Federica Lodi; Manuel Sanchez; Milagros Galisteo; Antonio Zarzuelo; Francisco Pérez-Vizcaíno; Juan Duarte
Genistein restores caveolin-1 and AT-1 receptor expression and vascular function in large vessels of ovariectomized hypertensive rats.
Menopause (New York, N.Y.) 2007;14(5):933-40.
2007: Rosario Jiménez; Rocío López-Sepúlveda; María Kadmiri; Miguel Romero; Rocío Vera; Manuel Sanchez; Félix Vargas; Francisco O'Valle; Antonio Zarzuelo; Montserrat Dueñas; Celestino Santos-Buelga; Juan Duarte
Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase.
Free radical biology & medicine 2007;43(3):462-73.
2007: Juan Román; Alberto Fernández de Arriba; Sonia Barrón; Pedro Michelena; Marta Giral; Manuel Merlos; Elvira Bailón; Mònica Comalada; Julio Gálvez; Antonio Zarzuelo; Isabel Ramis
UR-1505, a new salicylate, blocks T cell activation through nuclear factor of activated T cells.
Molecular pharmacology 2007;72(2):269-79.
2007: Abdelali Daddaoua; Enrique Martínez-Plata; Rocío López-Posadas; José María Vieites; Mercedes González; Pilar Requena; Antonio Zarzuelo; María Dolores Suárez; Fermin Sanchez de Medina; Olga Martínez-Augustin
Active hexose correlated compound acts as a prebiotic and is antiinflammatory in rats with hapten-induced colitis.
The Journal of nutrition 2007;137(5):1222-8.
2007: Isabel Ballester; Abdelali Daddaoua; R López-Posadas; Ana Nieto; María Dolores Suárez; Antonio Zarzuelo; Olga Martínez-Augustin; Fermin Sanchez de Medina
The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats.
British journal of pharmacology 2007;151(2):206-15.
2007: Rocío Vera; Manuel Sanchez; Milagros Galisteo; Inmaculada Concepción Villar; Rosario Jimenez; Antonio Zarzuelo; Francisco Pérez-Vizcaíno; Juan Duarte
Chronic administration of genistein improves endothelial dysfunction in spontaneously hypertensive rats: involvement of eNOS, caveolin and calmodulin expression and NADPH oxidase activity.
Clinical science (London, England : 1979) 2007;112(3):183-91.
2007: Laura Peran; Saleta Sierra; Mònica Comalada; Federico Lara-Villoslada; Elvira Bailón; Ana Nieto; Angel Concha; Mónica Olivares; Antonio Zarzuelo; Jordi Xaus; Julio Gálvez
A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis.
The British journal of nutrition 2007;97(1):96-103.
2006: Julio Galvez; Juliano de Souza Gracioso; Desirée Camuesco; Julio Galvez; Wagner Vilegas; Alba Regina Monteiro Souza Brito; Antonio Zarzuelo
Intestinal antiinflammatory activity of a lyophilized infusion of Turnera ulmifolia in TNBS rat colitis.
Fitoterapia 2006;77(7-8):515-20.
2006: Laura Peran; Desirée Camuesco; Mònica Comalada; Ana Nieto; Angel Concha; José Luis Adrio; Mónica Olivares; Jordi Xaus; Antonio Zarzuelo; Julio Galvez
Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis.
International journal of colorectal disease 2006;21(8):737-46.
2006: Mònica Comalada; Isabel Ballester; Elvira Bailón; Saleta Sierra; Jordi Xaus; Julio Gálvez; Fermin Sanchez de Medina; Antonio Zarzuelo
Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship.
Biochemical pharmacology 2006;72(8):1010-21.
2006: Federico Lara-Villoslada; Oscar de Haro; Desirée Camuesco; Mònica Comalada; Javier Velasco; Antonio Zarzuelo; Jordi Xaus; Julio Galvez
Short-chain fructooligosaccharides, in spite of being fermented in the upper part of the large intestine, have anti-inflammatory activity in the TNBS model of colitis.
European journal of nutrition 2006;45(7):418-25.
2006: Mònica Comalada; Elvira Bailón; Oscar de Haro; Federico Lara-Villoslada; Jordi Xaus; Antonio Zarzuelo; Julio Gálvez
The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype.
Journal of cancer research and clinical oncology 2006;132(8):487-97.
2006: Desirée Camuesco; Mònica Comalada; Angel Concha; Ana Nieto; Saleta Sierra; Jordi Xaus; Antonio Zarzuelo; Julio Gálvez
Intestinal anti-inflammatory activity of combined quercitrin and dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, in rats with DSS-induced colitis.
Clinical nutrition (Edinburgh, Scotland) 2006;25(3):466-76.
2006: M Isabel Baena; María José Faus; Paloma C Fajardo; Francisco M Luque; Francisco Sierra; Jose Martinez-Olmos; Andres Cabrera; Fernando Fernandez-Llimos; Fernando Martinez-Martinez; José Jiménez; Antonio Zarzuelo
Medicine-related problems resulting in emergency department visits.
European journal of clinical pharmacology 2006;62(5):387-93.
2006: Abdelali Daddaoua; Víctor Puerta; Pilar Requena; Antonio Martínez-Férez; Emilia Guadix; Fermin Sanchez de Medina; Antonio Zarzuelo; María Dolores Suárez; Julio Boza; Olga Martínez-Augustin
Goat milk oligosaccharides are anti-inflammatory in rats with hapten-induced colitis.
The Journal of nutrition 2006;136(3):672-6.
2006: Bartolome Quintero; Elena Planells; María del Carmen Cabeza; Javier Esquivias; María del Pilar Gutiérrez; Cristina Sánchez; Pilar Aranda; Antonio Zarzuelo; Juan Llopis
Tumor-promoting activity of p-hydroxybenzenediazonium is accelerated in Mg-deficient rats.
Chemico-biological interactions 2006;159(3):186-95.
2006: Manuel Sanchez; Milagros Galisteo; Rocío Vera; Inmaculada Concepción Villar; Antonio Zarzuelo; Juan Tamargo; Francisco Pérez-Vizcaíno; Juan Duarte
Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats.
Journal of hypertension 2006;24(1):75-84.
2005: Milagros Galisteo; Manuel Sanchez; Rocío Vera; Mercedes González; Anna Anguera; Juan Duarte; Antonio Zarzuelo
A diet supplemented with husks of Plantago ovata reduces the development of endothelial dysfunction, hypertension, and obesity by affecting adiponectin and TNF-alpha in obese Zucker rats.
The Journal of nutrition 2005;135(10):2399-404.
2005: Laura Peran; Desirée Camuesco; Mònica Comalada; Ana Nieto; Angel Concha; Maria Paz Diaz-Ropero; Mónica Olivares; Jordi Xaus; Antonio Zarzuelo; Julio Galvez
Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis.
World journal of gastroenterology : WJG 2005;11(33):5185-92.
2005: Inmaculada Concepción Villar; Rocío Vera; Milagros Galisteo; Francisco O'Valle; Miguel Romero; Antonio Zarzuelo; Juan Duarte
Endothelial nitric oxide production stimulated by the bioflavonoid chrysin in rat isolated aorta.
Planta medica 2005;71(9):829-34.
2005: Rocío Vera; Milagros Galisteo; Inmaculada Concepción Villar; Manuel Sanchez; Antonio Zarzuelo; Francisco Pérez-Vizcaíno; Juan Duarte
Soy isoflavones improve endothelial function in spontaneously hypertensive rats in an estrogen-independent manner: role of nitric-oxide synthase, superoxide, and cyclooxygenase metabolites.
The Journal of pharmacology and experimental therapeutics 2005;314(3):1300-9.
2005: Julio Galvez; M Elena Rodríguez-Cabezas; Antonio Zarzuelo
Effects of dietary fiber on inflammatory bowel disease.
Molecular nutrition & food research 2005;49(6):601-8.
2005: Isabel Ballester; Raquel González; Ana Nieto; Antonio Zarzuelo; Fermin Sanchez de Medina
Monochloramine induces acute and protracted colitis in the rat: response to pharmacological treatment.
Life sciences 2005;76(25):2965-80.
2005: Abdelali Daddaoua; Víctor Puerta; Antonio Zarzuelo; María Dolores Suárez; Fermin Sanchez de Medina; Olga Martínez-Augustin
Bovine glycomacropeptide is anti-inflammatory in rats with hapten-induced colitis.
The Journal of nutrition 2005;135(5):1164-70.
2005: Desirée Camuesco; Julio Gálvez; Ana Nieto; Mònica Comalada; M Elena Rodríguez-Cabezas; Angel Concha; Jordi Xaus; Antonio Zarzuelo
Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis.
The Journal of nutrition 2005;135(4):687-94.
2005: Desirée Camuesco; Laura Peran; Mònica Comalada; Ana Nieto; Luiz C Di Stasi; M Elena Rodriguez-Cabezas; Angel Concha; Antonio Zarzuelo; Julio Galvez
Preventative effects of lactulose in the trinitrobenzenesulphonic acid model of rat colitis.
Inflammatory bowel diseases 2005;11(3):265-71.
2005: Rubén Pérez-Navarro; Isabel Ballester; Antonio Zarzuelo; Fermin Sanchez de Medina
Disturbances in epithelial ionic secretion in different experimental models of colitis.
Life sciences 2005;76(13):1489-501.
2005: María Francisca García-Saura; Milagros Galisteo; Inmaculada Concepción Villar; Almudena Bermejo; Antonio Zarzuelo; Félix Vargas; Juan Duarte
Effects of chronic quercetin treatment in experimental renovascular hypertension.
Molecular and cellular biochemistry 2005;270(1-2):147-55.
2005: R Pérez-Navarro; Olga Martínez-Augustin; Isabel Ballester; Antonio Zarzuelo; Fermin Sanchez de Medina
Experimental inflammation of the rat distal colon inhibits ion secretion in the proximal colon by affecting the enteric nervous system.
Naunyn-Schmiedeberg's archives of pharmacology 2005;371(2):114-21.
2005: Mònica Comalada; Desirée Camuesco; Saleta Sierra; Isabel Ballester; Jordi Xaus; Julio Gálvez; Antonio Zarzuelo
In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway.
European journal of immunology 2005;35(2):584-92.
2004: Fermin Sanchez de Medina; Olga Martínez-Augustin; Raquel González; Isabel Ballester; Ana Nieto; Julio Gálvez; Antonio Zarzuelo
Induction of alkaline phosphatase in the inflamed intestine: a novel pharmacological target for inflammatory bowel disease.
Biochemical pharmacology 2004;68(12):2317-26.
2004: Desirée Camuesco; Mònica Comalada; M Elena Rodríguez-Cabezas; Ana Nieto; Miguel Lorente; Angel Concha; Antonio Zarzuelo; Julio Gálvez
The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression.
British journal of pharmacology 2004;143(7):908-18.
2004: Inmaculada Concepción Villar; Milagros Galisteo; Rocío Vera; Francisco O'Valle; María Francisca García-Saura; Antonio Zarzuelo; Juan Duarte
Effects of the dietary flavonoid chrysin in isolated rat mesenteric vascular bed.
Journal of vascular research 2004;41(6):509-16.
2004: Milagros Galisteo; María Francisca García-Saura; Rosario Jiménez; Inmaculada Concepción Villar; Antonio Zarzuelo; Félix Vargas; Juan Duarte
Effects of chronic quercetin treatment on antioxidant defence system and oxidative status of deoxycorticosterone acetate-salt-hypertensive rats.
Molecular and cellular biochemistry 2004;259(1-2):91-9.
2004: Milagros Galisteo; María Francisca García-Saura; Rosario Jiménez; Inmaculada Concepción Villar; Rosemary Wangensteen; Antonio Zarzuelo; Félix Vargas; Juan Duarte
Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil.
Planta medica 2004;70(4):334-41.
2004: Luiz C Di Stasi; Desirée Camuesco; Ana Nieto; Wagner Vilegas; Antonio Zarzuelo; Julio Galvez
Intestinal anti-inflammatory activity of paepalantine, an isocoumarin isolated from the capitula of Paepalanthus bromelioides, in the trinitrobenzenesulphonic acid model of rat colitis.
Planta medica 2004;70(4):315-20.
2004: Raquel González; Fermin Sanchez de Medina; Olga Martínez-Augustin; Ana Nieto; Julio Gálvez; Severiano Risco; Antonio Zarzuelo
Anti-inflammatory effect of diosmectite in hapten-induced colitis in the rat.
British journal of pharmacology 2004;141(6):951-60.
2003: Julio Gálvez; Margarita Garrido; M Elena Rodríguez-Cabezas; Isabel Ramis; Fermin Sanchez de Medina; Manuel Merlos; Antonio Zarzuelo
The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production.
Inflammatory bowel diseases 2003;9(6):363-71.
2003: M Elena Rodríguez-Cabezas; Julio Gálvez; Desirée Camuesco; Miguel Lorente; Angel Concha; O Martinez-Augustin; Luis Redondo; Antonio Zarzuelo
Intestinal anti-inflammatory activity of dietary fiber (Plantago ovata seeds) in HLA-B27 transgenic rats.
Clinical nutrition (Edinburgh, Scotland) 2003;22(5):463-71.
2003: Almudena Bermejo; Antonio Zarzuelo; Juan Duarte
In vivo vascular effects of genistein on a rat model of septic shock induced by lipopolysaccharide.
Journal of cardiovascular pharmacology 2003;42(3):329-38.
2002: M Elena Rodríguez-Cabezas; Julio Gálvez; Miguel Lorente; Angel Concha; Desirée Camuesco; Samira Azzouz; Antonio Osuna; Luis Redondo; Antonio Zarzuelo
Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats.
The Journal of nutrition 2002;132(11):3263-71.
2002: Inmaculada Concepción Villar; Rosario Jiménez; Milagros Galisteo; Maria Francisca Garcia-Saura; Antonio Zarzuelo; Juan Duarte
Effects of chronic chrysin treatment in spontaneously hypertensive rats.
Planta medica 2002;68(9):847-50.
2002: Juan Duarte; Rosario Jiménez; Francisco O'Valle; Milagros Galisteo; Raquel Pérez-Palencia; Félix Vargas; Francisco Pérez-Vizcaíno; Antonio Zarzuelo; Juan Tamargo
Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats.
Journal of hypertension 2002;20(9):1843-54.
2002: Fermin Sanchez de Medina; R Pérez; Olga Martínez-Augustin; Raquel González; Miguel Lorente; Julio Gálvez; Antonio Zarzuelo
Disturbances of colonic ion secretion in inflammation: role of the enteric nervous system and cAMP.
Pflügers Archiv : European journal of physiology 2002;444(3):378-88.
2002: Fermin Sanchez de Medina; B Vera; Julio Gálvez; Antonio Zarzuelo
Effect of quercitrin on the early stages of hapten induced colonic inflammation in the rat.
Life sciences 2002;70(26):3097-108.
2002: Rosario Jiménez; Antonio Zarzuelo; Milagros Galisteo; Juan Duarte
Involvement of protein kinase C and Na+/K+-ATPase in the contractile response induced by myricetin in rat isolated aorta.
Planta medica 2002;68(2):133-7.
2001: Julio Gálvez; G Coelho; ME Crespo; T Cruz; M Elena Rodríguez-Cabezas; Angel Concha; M Gonzalez; Antonio Zarzuelo
Intestinal anti-inflammatory activity of morin on chronic experimental colitis in the rat.
Alimentary pharmacology & therapeutics 2001;15(12):2027-39.
2001: Raquel González; Fermin Sanchez de Medina; Julio Gálvez; M Elena Rodríguez-Cabezas; Juan Duarte; Antonio Zarzuelo
Dietary vitamin E supplementation protects the rat large intestine from experimental inflammation.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 2001;71(4):243-50.
2001: Juan Duarte; Milagros Galisteo; MA Ocete; Francisco Pérez-Vizcaino; Antonio Zarzuelo; Juan Tamargo
Effects of chronic quercetin treatment on hepatic oxidative status of spontaneously hypertensive rats.
Molecular and cellular biochemistry 2001;221(1-2):155-60.
2001: Juan Duarte; R Pérez-Palencia; Félix Vargas; MA Ocete; Francisco Pérez-Vizcaino; Antonio Zarzuelo; Juan Tamargo
Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats.
British journal of pharmacology 2001;133(1):117-24.
2001: T Cruz; Julio Gálvez; E Crespo; MA Ocete; Antonio Zarzuelo
Effects of silymarin on the acute stage of the trinitrobenzenesulphonic acid model of rat colitis.
Planta medica 2001;67(1):94-6.
2000: Julio Gálvez; M Garrido; Manuel Merlos; María Isabel Torres; Antonio Zarzuelo
Intestinal anti-inflammatory activity of UR-12746, a novel 5-ASA conjugate, on acute and chronic experimental colitis in the rat.
British journal of pharmacology 2000;130(8):1949-59.
2000: Juan Duarte; A I Torres; Antonio Zarzuelo
Cardiovascular effects of visnagin on rats.
Planta medica 2000;66(1):35-9.
1999: ME Crespo; Julio Gálvez; T Cruz; MA Ocete; Antonio Zarzuelo
Anti-inflammatory activity of diosmin and hesperidin in rat colitis induced by TNBS.
Planta medica 1999;65(7):651-3.
1999: Rosario Jiménez; Emile Andriambeloson; Juan Duarte; Ramaroson Andriantsitohaina; J Jiménez; Francisco Pérez-Vizcaino; Antonio Zarzuelo; Juan Tamargo
Involvement of thromboxane A2 in the endothelium-dependent contractions induced by myricetin in rat isolated aorta.
British journal of pharmacology 1999;127(7):1539-44.
1999: Juan Duarte; A Martinez; Almudena Bermejo; B Vera; M J Gámez; P Cabo; Antonio Zarzuelo
Cardiovascular effects of captopril and enalapril in obese Zucker rats.
European journal of pharmacology 1999;365(2-3):225-32.
1999: Juan Duarte; Lugnier Claire; A I Torres; Francisco Pérez-Vizcaino; Antonio Zarzuelo; Juan Tamargo
Effects of visnagin on cyclic nucleotide phosphodiesterases and their role in its inhibitory effects on vascular smooth muscle contraction.
General pharmacology 1999;32(1):71-4.
1998: MA Ocete; Julio Gálvez; ME Crespo; T Cruz; Mercedes González; María Isabel Torres; Antonio Zarzuelo
Effects of morin on an experimental model of acute colitis in rats.
Pharmacology 1998;57(5):261-70.
1998: T Cruz; Julio Gálvez; MA Ocete; ME Crespo; F Sánchez de Medina L-H; Antonio Zarzuelo
Oral administration of rutoside can ameliorate inflammatory bowel disease in rats.
Life sciences 1998;62(7):687-95.
1997: Juan Duarte; MA Ocete; Francisco Pérez-Vizcaino; Antonio Zarzuelo; Juan Tamargo
Effect of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase.
European journal of pharmacology 1997;338(1):25-33.
1997: Julio Gálvez; T Cruz; E Crespo; MA Ocete; Miguel Lorente; Fermin Sanchez de Medina; Antonio Zarzuelo
Rutoside as mucosal protective in acetic acid-induced rat colitis.
Planta medica 1997;63(5):409-14.
1997: J Durate; I Vallejo; Francisco Pérez-Vizcaino; Rosario Jiménez; Antonio Zarzuelo; Juan Tamargo
Effects of visnadine on rat isolated vascular smooth muscles.
Planta medica 1997;63(3):233-6.
1997: Fermin Sanchez de Medina; Julio Gálvez; M González; Antonio Zarzuelo; K E Barrett
Effects of quercetin on epithelial chloride secretion.
Life sciences 1997;61(20):2049-55.
1996: Fermin Sanchez de Medina; Julio Gálvez; J A Romero; Antonio Zarzuelo
Effect of quercitrin on acute and chronic experimental colitis in the rat.
The Journal of pharmacology and experimental therapeutics 1996;278(2):771-9.
1996: Antonio Zarzuelo; I Jiménez; M J Gámez; P Utrilla; I Fernadez; María Isabel Torres; I Osuna
Effects of luteolin 5-O-beta-rutinoside in streptozotocin-induced diabetic rats.
Life sciences 1996;58(25):2311-6.
1995: Juan Duarte; Francisco Pérez-Vizcaíno; A I Torres; Antonio Zarzuelo; J Jiménez; Juan Tamargo
Vasodilator effects of visnagin in isolated rat vascular smooth muscle.
European journal of pharmacology 1995;286(2):115-22.
1995: J Galvez; José Pedro De la Cruz; Antonio Zarzuelo; Felipe Sanchez de la Cuesta
Flavonoid inhibition of enzymic and nonenzymic lipid peroxidation in rat liver differs from its influence on the glutathione-related enzymes.
Pharmacology 1995;51(2):127-33.
1995: Julio Gálvez; Fermin Sanchez de Medina; J Jiménez; María Isabel Torres; MI Fernández; M C Núñez; Antonio Ríos; Angel Gil; Antonio Zarzuelo
Effect of quercitrin on lactose-induced chronic diarrhoea in rats.
Planta medica 1995;61(4):302-6.
1994: J Galvez; José Pedro De la Cruz; Antonio Zarzuelo; Fermin Sanchez de Medina; J Jimenez; Felipe Sanchez de la Cuesta
Oral administration of quercitrin modifies intestinal oxidative status in rats.
General pharmacology 1994;25(6):1237-43.
1994: Juan Duarte; Francisco Pérez-Vizcaíno; Antonio Zarzuelo; J Jiménez; Juan Tamargo
Inhibitory effects of quercetin and staurosporine on phasic contractions in rat vascular smooth muscle.
European journal of pharmacology 1994;262(1-2):149-56.
1994: Fermin Sanchez de Medina; M J Gámez; I Jiménez; J Jiménez; J I Osuna; Antonio Zarzuelo
Hypoglycemic activity of juniper "berries".
Planta medica 1994;60(3):197-200.
1993: S Martin; E Padilla; MA Ocete; J Galvez; J Jiménez; Antonio Zarzuelo
Anti-inflammatory activity of the essential oil of Bupleurum fruticescens.
Planta medica 1993;59(6):533-6.
1993: Juan Duarte; Francisco Pérez-Vizcaíno; Antonio Zarzuelo; J Jiménez; Juan Tamargo
Aminophylline preferentially inhibits chloroethylclonidine-insensitive alpha-adrenoceptor-mediated contractions in rat aorta.
General pharmacology 1993;24(6):1359-64.
1993: Juan Duarte; Francisco Pérez-Vizcaíno; Antonio Zarzuelo; J Jiménez; Juan Tamargo
Vasodilator effects of quercetin in isolated rat vascular smooth muscle.
European journal of pharmacology 1993;239(1-3):1-7.
1993: J Galvez; Antonio Zarzuelo; ME Crespo; Miguel Lorente; MA Ocete; J Jiménez
Antidiarrhoeic activity of Euphorbia hirta extract and isolation of an active flavonoid constituent.
Planta medica 1993;59(4):333-6.
1993: Juan Duarte; O Pérez; Antonio Zarzuelo; J Jiménez; Francisco Pérez-Vizcaíno; Juan Tamargo
Effects of oleuropeoside in isolated guinea-pig atria.
Planta medica 1993;59(4):318-22.
1993: Juan Duarte; Francisco Pérez-Vizcaíno; P Utrilla; J Jiménez; Juan Tamargo; Antonio Zarzuelo
Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships.
General pharmacology 1993;24(4):857-62.
1993: Julio Gálvez; ME Crespo; J Jiménez; A Suárez; Antonio Zarzuelo
Antidiarrhoeic activity of quercitrin in mice and rats.
The Journal of pharmacy and pharmacology 1993;45(2):157-9.
1992: M Gonzalez; Antonio Zarzuelo; M J Gamez; M P Utrilla; J Jimenez; I Osuna
Hypoglycemic activity of olive leaf.
Planta medica 1992;58(6):513-5.
1992: Juan Duarte; Francisco Pérez-Vizcaino; J Jimenez; Antonio Zarzuelo; Juan Tamargo
Effects of aminophylline on contractions and 45Ca uptake in isolated rat vascular smooth muscle.
General pharmacology 1992;23(4):601-6.
1992: J Galvez Peralta; Antonio Zarzuelo; R Busson; C Cobbaert; P de Witte
(-)-Epicatechin-3-galloyl ester: a secretagogue compound from the bark of Sclerocarya birrea.
Planta medica 1992;58(2):174-5.
1991: Antonio Zarzuelo; Juan Duarte; J Jiménez; M González; M P Utrilla
Vasodilator effect of olive leaf.
Planta medica 1991;57(5):417-9.
1990: M J Gamez; J Jimenez; C Navarro; Antonio Zarzuelo
Study of the essential oil of Lavandula dentata L.
Die Pharmazie 1990;45(1):69-70.
1990: Antonio Zarzuelo; S Risco; M J Gámez; J Jimenez; M Cámara; M A Martinez
Hypoglycemic action of Salvia lavandulifolia Vahl. spp. oxyodon:a contribution to studies on the mechanism of action.
Life sciences 1990;47(11):909-15.
1990: M D Pérez Raya; Antonio Zarzuelo; J M Duarte; J Jiménez; C Navarro
Chlorpromazine and clothiapine actions at the level of the CNS and vas deferens.
Pharmaceutica acta Helvetiae 1990;65(8):228-32.
1989: MA Ocete; S Risco; Antonio Zarzuelo; J Jimenez
Pharmacological activity of the essential oil of Bupleurum gibraltaricum: anti-inflammatory activity and effects on isolated rat uteri.
Journal of ethnopharmacology 1989;25(3):305-13.
1989: M L Gil; J Jimenez; MA Ocete; Antonio Zarzuelo; M M Cabo
Comparative study of different essential oils of Bupleurum gibraltaricum Lamarck.
Die Pharmazie 1989;44(4):284-7.
1989: I Lorente; MA Ocete; Antonio Zarzuelo; M M Cabo; J Jimenez
Bioactivity of the essential oil of Bupleurum fruticosum.
Journal of natural products 1989;52(2):267-72.
1988: M J Gamez; Antonio Zarzuelo; S Risco; P Utrilla; J Jimenez
Hypoglycemic activity in various species of the genus Lavandula. Part 2: Lavandula dentata and Lavandula latifolia.
Die Pharmazie 1988;43(6):441-2.
1987: M J Gámez; J Jiménez; S Risco; Antonio Zarzuelo
Hypoglycemic activity in various species of the genus Lavandula. Part 1: Lavandula stoechas L. and Lavandula multifida L.
Die Pharmazie 1987;42(10):706-7.
1986: J Jimenez; S Risco; T Ruiz; Antonio Zarzuelo
Hypoglycemic activity of Salvia lavandulifolia.
Planta medica 1986;(4):260-2.