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Walter Zawalich

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Ramanaiah Mamillapalli; Joshua N VanHouten; Walter S Zawalich; John J Wysolmerski
Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells.
Walter S Zawalich; Kathleen C Zawalich
Enhanced activation of phospholipase C and insulin secretion from islets incubated in fatty acid-free bovine serum albumin.
Walter S Zawalich; Hanae Yamazaki; Kathleen C Zawalich
Biphasic insulin secretion from freshly isolated or cultured, perifused rodent islets: comparative studies with rats and mice.

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2008: Ramanaiah Mamillapalli; Joshua N VanHouten; Walter S Zawalich; John J Wysolmerski
Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells.
The Journal of biological chemistry 2008;283(36):24435-47.
2008: Walter S Zawalich; Kathleen C Zawalich
Enhanced activation of phospholipase C and insulin secretion from islets incubated in fatty acid-free bovine serum albumin.
Metabolism: clinical and experimental 2008;57(2):290-8.
2008: Walter S Zawalich; Hanae Yamazaki; Kathleen C Zawalich
Biphasic insulin secretion from freshly isolated or cultured, perifused rodent islets: comparative studies with rats and mice.
Metabolism: clinical and experimental 2008;57(1):30-9.
2007: Walter S Zawalich; Kathleen C Zawalich; Hanae Yamazaki
Divergent effects of epinephrine and prostaglandin E2 on glucose-induced insulin secretion from perifused rat islets.
Metabolism: clinical and experimental 2007;56(1):12-8.
2006: Hanae Yamazaki; Kathleen C Zawalich; Walter S Zawalich
Desensitization of the pancreatic beta-cell: effects of sustained physiological hyperglycemia and potassium.
American journal of physiology. Endocrinology and metabolism 2006;291(6):H1381-7.
2006: Isabelle Millet; F Susan Wong; Werner Gurr; Li Wen; Walter S Zawalich; E Allison Green; Richard A Flavell; Robert S Sherwin
Targeted expression of the anti-apoptotic gene CrmA to NOD pancreatic islets protects from autoimmune diabetes.
Journal of autoimmunity 2006;26(1):7-15.
2006: Walter S Zawalich; Gregory J Tesz; Hanae Yamazaki; Kathleen C Zawalich; William M Philbrick
Dexamethasone suppresses phospholipase C activation and insulin secretion from isolated rat islets.
Metabolism: clinical and experimental 2006;55(1):35-42.
2006: Hanae Yamazaki; William M Philbrick; Kathleen C Zawalich; Walter S Zawalich
Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine.
American journal of physiology. Endocrinology and metabolism 2006;290(1):E26-E33.
2005: David E Johnson; Hanae Yamazaki; Karen M Ward; Anne W Schmidt; Wesley S Lebel; Judith L Treadway; E Michael Gibbs; Walter S Zawalich; Hans Rollema
Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia.
Diabetes 2005;54(5):1552-8.
2004: Walter S Zawalich; H Yamazaki; Kathleen C Zawalich; G Cline
Comparative effects of amino acids and glucose on insulin secretion from isolated rat or mouse islets.
The Journal of endocrinology 2004;183(2):309-19.
2004: Yong Lian Zhu; Alexander Abdo; Joan F Gesmonde; Kathleen C Zawalich; Walter S Zawalich; Priscilla S Dannies
Aggregation and lack of secretion of most newly synthesized proinsulin in non-beta-cell lines.
Endocrinology 2004;145(8):3840-9.
2004: Walter S Zawalich; Kathleen C Zawalich; Gregory J Tesz; Makoto M Taketo; John Sterpka; William M Philbrick; Minoru MATSUI
Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses.
Biochemical and biophysical research communications 2004;315(4):872-6.
2004: Walter S Zawalich; Gregory J Tesz; Kathleen C Zawalich
Effects of prior 5-hydroxytryptamine exposure on rat islet insulin secretory and phospholipase C responses.
Endocrine 2004;23(1):11-6.
2003: Walter S Zawalich; Gregory J Tesz; Kathleen C Zawalich
Contrasting effects of nateglinide and rosiglitazone on insulin secretion and phospholipase C activation.
Metabolism: clinical and experimental 2003;52(11):1393-9.
2002: Paolo R O Salvalaggio; Songyan Deng; Charlotte Eielson Ariyan; Isabelle Millet; Walter S Zawalich; Giacomo P Basadonna; David M Rothstein
Islet filtration: a simple and rapid new purification procedure that avoids ficoll and improves islet mass and function.
Transplantation 2002;74(6):877-9.
2002: Walter S Zawalich; Gregory J Tesz; Kathleen C Zawalich
Inhibitors of phosphatidylinositol 3-kinase amplify insulin release from islets of lean but not obese mice.
The Journal of endocrinology 2002;174(2):247-58.
2002: Walter S Zawalich; Kathleen C Zawalich
Effects of glucose, exogenous insulin, and carbachol on C-peptide and insulin secretion from isolated perifused rat islets.
The Journal of biological chemistry 2002;277(29):26233-7.
2002: John Gerard Geisler; Walter S Zawalich; Kathleen C Zawalich; Jonathan R T Lakey; Hans A Stukenbrok; Anthony J Milici; Walter Soeller
Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.
Diabetes 2002;51(7):2158-69.
2001: Walter S Zawalich; Gregory J Tesz; Kathleen C Zawalich
Are 5-hydroxytryptamine-preloaded beta-cells an appropriate physiologic model system for establishing that insulin stimulates insulin secretion?
The Journal of biological chemistry 2001;276(40):37120-3.
2001: T Ort; Sergey V Voronov; Jun Guo; Kathleen C Zawalich; Stanley Froehner; Walter S Zawalich; Michele Solimena
Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion.
The EMBO journal 2001;20(15):4013-23.
2001: Walter S Zawalich; Kathleen C Zawalich
Effects of protein kinase C inhibitors on insulin secretory responses from rodent pancreatic islets.
Molecular and cellular endocrinology 2001;177(1-2):95-105.
2001: Walter S Zawalich; Kathleen C Zawalich; Gregory J Tesz; John Sterpka; William M Philbrick
Insulin secretion and IP levels in two distant lineages of the genus Mus: comparisons with rat islets.
American journal of physiology. Endocrinology and metabolism 2001;280(5):E720-8.
2000: Walter S Zawalich; M Bonnet-Eymard; Kathleen C Zawalich
Insulin secretion, inositol phosphate levels, and phospholipase C isozymes in rodent pancreatic islets.
Metabolism: clinical and experimental 2000;49(9):1156-63.
2000: Walter S Zawalich; Kathleen C Zawalich
A link between insulin resistance and hyperinsulinemia: inhibitors of phosphatidylinositol 3-kinase augment glucose-induced insulin secretion from islets of lean, but not obese, rats.
Endocrinology 2000;141(9):3287-95.
2000: Walter S Zawalich; Kathleen C Zawalich
Glucose-induced insulin secretion from islets of fasted rats: modulation by alternate fuel and neurohumoral agonists.
The Journal of endocrinology 2000;166(1):111-20.
1998: Walter S Zawalich; M Bonnet-Eymard; Kathleen C Zawalich
Glucose-induced desensitization of the pancreatic beta-cell is species dependent.
The American journal of physiology 1998;275(6 Pt 1):E917-24.
1998: Walter S Zawalich; M Bonnet-Eymard; Kathleen C Zawalich; G C Yaney
Chronic exposure to TPA depletes PKC alpha and augments Ca-dependent insulin secretion from cultured rat islets.
The American journal of physiology 1998;274(5 Pt 1):C1388-96.
1997: Walter S Zawalich; Kathleen C Zawalich
Regulation of insulin secretion via ATP-sensitive K+ channel independent mechanisms: role of phospholipase C.
The American journal of physiology 1997;272(4 Pt 1):E671-7.
1997: Walter S Zawalich; Kathleen C Zawalich
Influence of pyruvic acid methyl ester on rat pancreatic islets. Effects on insulin secretion, phosphoinositide hydrolysis, and sensitization of the beta cell.
The Journal of biological chemistry 1997;272(6):3527-31.
1997: Walter S Zawalich; M Bonnet-Eymard; Kathleen C Zawalich
Signal transduction in pancreatic beta-cells: regulation of insulin secretion by information flow in the phospholipase C/protein kinase C pathway.
Frontiers in bioscience : a journal and virtual library 1997;2():d160-72.
1996: Walter S Zawalich; Kathleen C Zawalich
Regulation of insulin secretion by phospholipase C.
The American journal of physiology 1996;271(3 Pt 1):E409-16.
1996: Walter S Zawalich; Kathleen C Zawalich; G G Kelley
Time-dependent effects of cholinergic stimulation on beta cell responsiveness.
Pflügers Archiv : European journal of physiology 1996;432(4):589-96.
1996: Walter S Zawalich; Kathleen C Zawalich
Signal transduction in isolated islets from the ob/ob mouse: enhanced sensitivity of protein kinase C to stimulation.
Biochemical and biophysical research communications 1996;223(3):618-23.
1996: Walter S Zawalich; Kathleen C Zawalich
Species differences in the induction of time-dependent potentiation of insulin secretion.
Endocrinology 1996;137(5):1664-9.
1996: Walter S Zawalich; Kathleen C Zawalich
Glucagon-like peptide-1 stimulates insulin secretion but not phosphoinositide hydrolysis from islets desensitized by prior exposure to high glucose or the muscarinic agonist carbachol.
Metabolism: clinical and experimental 1996;45(2):273-8.
1996: Rupangi C Vasavada; C Cavaliere; Augustine D'ercole; Pamela Dann; W J Burtis; A L Madlener; Kathleen C Zawalich; Walter S Zawalich; William M Philbrick; Andrew F Stewart
Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia.
The Journal of biological chemistry 1996;271(2):1200-8.
1995: Walter S Zawalich; Kathleen C Zawalich; G G Kelley
Regulation of insulin release by phospholipase C activation in mouse islets: differential effects of glucose and neurohumoral stimulation.
Endocrinology 1995;136(11):4903-9.
1995: Walter S Zawalich; Kathleen C Zawalich; G G Kelley
Effects of short-term culturing on islet phosphoinositide and insulin secretory responses to glucose and carbachol.
Acta diabetologica 1995;32(3):158-64.
1995: G G Kelley; Kathleen C Zawalich; Walter S Zawalich
Synergistic interaction of glucose and neurohumoral agonists to stimulate islet phosphoinositide hydrolysis.
The American journal of physiology 1995;269(3 Pt 1):E575-82.
1995: Walter S Zawalich; G G Kelley
The pathogenesis of NIDDM: the role of the pancreatic beta cell.
Diabetologia 1995;38(8):986-91.
1995: Walter S Zawalich; Kathleen C Zawalich; G G Kelley; Gerald I Shulman
Islet phosphoinositide hydrolysis and insulin secretory responses from prediabetic fa/fa ZDF rats.
Biochemical and biophysical research communications 1995;209(3):974-80.
1995: Howard Rasmussen; Kathleen C Zawalich; Walter S Zawalich
Metabolic activation of Ca(2+)-independent phosphoinositide hydrolysis in beta-cells and its role in the control of insulin secretion.
Endocrinology 1995;136(2):577-84.
1994: G G Kelley; Kathleen C Zawalich; Walter S Zawalich
Calcium and a mitochondrial signal interact to stimulate phosphoinositide hydrolysis and insulin secretion in rat islets.
Endocrinology 1994;134(4):1648-54.
1993: Walter S Zawalich; Kathleen C Zawalich; Gary W Cline; G Shulman; Howard Rasmussen
Comparative effects of monomethylsuccinate and glucose on insulin secretion from perifused rat islets.
Diabetes 1993;42(6):843-50.
1993: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
Influence of glucagon-like peptide-1 on beta cell responsiveness.
Regulatory peptides 1993;44(3):277-83.
1992: S Ganesan; R Calle; Kathleen C Zawalich; K Greenawalt; Walter S Zawalich; Gerald I Shulman; Howard Rasmussen
Immunocytochemical localization of alpha-protein kinase C in rat pancreatic beta-cells during glucose-induced insulin secretion.
The Journal of cell biology 1992;119(2):313-24.
1992: Walter S Zawalich; Kathleen C Zawalich
Biochemical mechanisms involved in monomethyl succinate-induced insulin secretion.
Endocrinology 1992;131(2):649-54.
1992: Walter S Zawalich; Kathleen C Zawalich
Glucosamine-induced desensitization of beta-cell responses: possible involvement of impaired information flow in the phosphoinositide cycle.
Endocrinology 1992;130(6):3135-42.
1992: Howard Rasmussen; Carlos M. Isales; S Ganesan; R Calle; Walter S Zawalich
Ca(2+)-cyclic AMP interactions in sustained cellular responses.
Ciba Foundation symposium 1992;164():98-108; discussion 108-12.
1991: Walter S Zawalich; Kathleen C Zawalich
Influence of staurosporine, nitrendipine and monooleoylglycerol on interleukin-1-induced insulin secretion and phosphoinositide hydrolysis.
Molecular and cellular endocrinology 1991;82(2-3):303-11.
1991: Walter S Zawalich; Kathleen C Zawalich; S Ganesan; R Calle; Howard Rasmussen
Influence of staurosporine on glucose-mediated and glucose-conditioned insulin secretion.
The Biochemical journal 1991;279 ( Pt 3)():807-13.
1991: Walter S Zawalich; Kathleen C Zawalich; S Ganesan; R Calle; Howard Rasmussen
Effects of the phorbol ester phorbol 12-myristate 13-acetate (PMA) on islet-cell responsiveness.
The Biochemical journal 1991;278 ( Pt 1)():49-56.
1991: Walter S Zawalich
Glyburide priming of beta cells. Possible involvement of phosphoinositide hydrolysis.
Biochemical pharmacology 1991;41(5):807-13.
1990: S Ganesan; R Calle; Kathleen C Zawalich; Joan I Smallwood; Walter S Zawalich; Howard Rasmussen
Glucose-induced translocation of protein kinase C in rat pancreatic islets.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9893-7.
1990: Howard Rasmussen; Kathleen C Zawalich; S Ganesan; R Calle; Walter S Zawalich
Physiology and pathophysiology of insulin secretion.
Diabetes care 1990;13(6):655-66.
1990: Walter S Zawalich; Kathleen C Zawalich
Forskolin-induced desensitization of pancreatic beta-cell insulin secretory responsiveness: possible involvement of impaired information flow in the inositol-lipid cycle.
Endocrinology 1990;126(5):2307-12.
1990: Walter S Zawalich
Multiple effects of increases in phosphoinositide hydrolysis on islets and their relationship to changing patterns of insulin secretion.
Diabetes research (Edinburgh, Scotland) 1990;13(3):101-11.
1990: Walter S Zawalich; Kathleen C Zawalich
Influence of monooleoylglycerol on islet cell phosphoinositide hydrolysis and insulin secretion.
Molecular and cellular endocrinology 1990;68(2-3):129-36.
1990: Walter S Zawalich; Kathleen C Zawalich; Gerald I Shulman; L Rossetti
Chronic in vivo hyperglycemia impairs phosphoinositide hydrolysis and insulin release in isolated perifused rat islets.
Endocrinology 1990;126(1):253-60.
1989: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
Cholinergic agonists prime the beta-cell to glucose stimulation.
Endocrinology 1989;125(5):2400-6.
1989: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
Interactions between lithium, inositol and mono-oleoylglycerol in the regulation of insulin secretion from isolated perifused rat islets.
The Biochemical journal 1989;262(2):557-61.
1989: Walter S Zawalich
Phosphoinositide hydrolysis and insulin secretion in response to glucose stimulation are impaired in isolated rat islets by prolonged exposure to the sulfonylurea tolbutamide.
Endocrinology 1989;125(1):281-6.
1989: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
The effect of monooleoylglycerol on insulin secretion from isolated perifused rat islets.
Diabetologia 1989;32(6):360-4.
1989: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
Interactions between cholinergic agonists and enteric factors in the regulation of insulin secretion from isolated perifused rat islets.
Acta endocrinologica 1989;120(6):702-7.
1989: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
The conditions under which rat islets are labelled with [3H]inositol alter the subsequent responses of these islets to a high glucose concentration.
The Biochemical journal 1989;259(3):743-9.
1989: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
Interleukin-1 alpha exerts glucose-dependent stimulatory and inhibitory effects on islet cell phosphoinositide hydrolysis and insulin secretion.
Endocrinology 1989;124(5):2350-7.
1989: Walter S Zawalich; B Dierolf; Kathleen C Zawalich
Interleukin-1 induces time-dependent potentiation in isolated rat islets: possible involvement of phosphoinositide hydrolysis.
Endocrinology 1989;124(2):720-6.
1989: Howard Rasmussen; P Barrett; Walter S Zawalich; Carlos M. Isales; P Stein; Joan I Smallwood; R McCarthy; Wendy B Bollag
Cycling of Ca2+ across the plasma membrane as a mechanism for generating a Ca2+ signal for cell activation.
Annals of the New York Academy of Sciences 1989;568():73-80.
1989: Walter S Zawalich; Kathleen C Zawalich
Interleukin 1 is a potent stimulator of islet insulin secretion and phosphoinositide hydrolysis.
The American journal of physiology 1989;256(1 Pt 1):E19-24.
1988: Walter S Zawalich; V A Diaz; Kathleen C Zawalich
Influence of cAMP and calcium on [3H]inositol efflux, inositol phosphate accumulation, and insulin release from isolated rat islets.
Diabetes 1988;37(11):1478-83.
1988: Walter S Zawalich; V A Diaz; Kathleen C Zawalich
Stimulatory effects of cholecystokinin on isolated perifused islets inhibited by potent and specific antagonist L 364718 [corrected].
Diabetes 1988;37(10):1432-7.
1988: Walter S Zawalich; Kathleen C Zawalich
Phosphoinositide hydrolysis and insulin release from isolated perifused rat islets. Studies with glucose.
Diabetes 1988;37(9):1294-300.
1988: Walter S Zawalich
Synergistic impact of cholecystokinin and gastric inhibitory polypeptide on the regulation of insulin secretion.
Metabolism: clinical and experimental 1988;37(8):778-81.
1988: Walter S Zawalich
Time-dependent potentiation of insulin release induced by alpha-ketoisocaproate and leucine in rats: possible involvement of phosphoinositide hydrolysis.
Diabetologia 1988;31(7):435-42.
1988: Walter S Zawalich; Kathleen C Zawalich
Induction of memory in rat pancreatic islets by tolbutamide. Dependence on ambient glucose level, calcium, and phosphoinositide hydrolysis.
Diabetes 1988;37(6):816-23.
1988: Walter S Zawalich; V A Diaz; Kathleen C Zawalich
Role of phosphoinositide metabolism in induction of memory in isolated perifused rat islets.
The American journal of physiology 1988;254(5 Pt 1):E609-16.
1988: Walter S Zawalich
Modulation of insulin secretion from beta-cells by phosphoinositide-derived second-messenger molecules.
Diabetes 1988;37(2):137-41.
1987: Walter S Zawalich; V A Diaz; Kathleen C Zawalich
Cholecystokinin-induced alterations in beta-cell sensitivity. Duration, specificity, and involvement of phosphoinositide metabolism.
Diabetes 1987;36(12):1420-4.
1987: L Rossetti; Gerald I Shulman; Walter S Zawalich
Physiological role of cholecystokinin in meal-induced insulin secretion in conscious rats. Studies with L 364718, a specific inhibitor of CCK-receptor binding.
Diabetes 1987;36(10):1212-5.
1987: Walter S Zawalich; N Takuwa; Y Takuwa; V A Diaz; Howard Rasmussen
Interactions of cholecystokinin and glucose in rat pancreatic islets.
Diabetes 1987;36(4):426-33.
1987: Walter S Zawalich; V A Diaz
Asperlicin antagonizes stimulatory effects of cholecystokinin on isolated islets.
The American journal of physiology 1987;252(3 Pt 1):E370-4.
1987: Walter S Zawalich; V A Diaz
Prior cholecystokinin exposure sensitizes islets of Langerhans to glucose stimulation.
Diabetes 1987;36(1):118-22.
1986: Walter S Zawalich; V A Diaz
Interleukin 1 inhibits insulin secretion from isolated perifused rat islets.
Diabetes 1986;35(10):1119-23.
1986: Walter S Zawalich; S B Cote; V A Diaz
Influence of cholecystokinin on insulin output from isolated perifused pancreatic islets.
Endocrinology 1986;119(2):616-21.
1985: Walter S Zawalich; Kathleen C Zawalich
Effect of exogenous phospholipase A2 on insulin secretion from perifused rat islets.
Diabetes 1985;34(5):471-6.
1984: Walter S Zawalich; Kathleen C Zawalich; Howard Rasmussen
Insulin secretion: combined tolbutamide, forskolin and TPA mimic action of glucose.
Cell calcium 1984;5(6):551-8.