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Rudolf Zechner

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THOMAS CHACKO PULINILKUNNIL; Terri J Waller; Martin E Young; Rudolf Zechner; Guenter Haemmerle; Erin E Kershaw; Petra C Kienesberger; Gregory Korbutt; Jeevan Nagendran; Jason R B Dyck
Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy.
Kathrin A Zierler; Robert Zimmermann; Sandra Eder; Doris Jaeger; Dagmar Kolb; Manju Kumari; Achim Lass; Bernd Mayer; Burkert Pieske; Nina M Pollak; Karina Preiss-Landl; Franz P W Radner; Gerald N Rechberger; Albrecht Schmidt; Gerald Woelkart; Rudolf Zechner; Guenter Haemmerle
Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.
Nina M Pollak; Thomas Rülicke; Renate Schreiber; Martina Schweiger; Rudolf Zechner; Kathrin A Zierler; Robert Zimmermann; Christoph Heier; Doris Jaeger; Dagmar Kolb; Stephanie Kolleritsch; Manju Kumari; Achim Lass; Philipp Markolin; Gernot F Grabner; Guenter Haemmerle
Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.

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2013: THOMAS CHACKO PULINILKUNNIL; Terri J Waller; Martin E Young; Rudolf Zechner; Guenter Haemmerle; Erin E Kershaw; Petra C Kienesberger; Gregory Korbutt; Jeevan Nagendran; Jason R B Dyck
Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy.
Diabetes 2013;62(5):1464-77.
2013: Kathrin A Zierler; Robert Zimmermann; Sandra Eder; Doris Jaeger; Dagmar Kolb; Manju Kumari; Achim Lass; Bernd Mayer; Burkert Pieske; Nina M Pollak; Karina Preiss-Landl; Franz P W Radner; Gerald N Rechberger; Albrecht Schmidt; Gerald Woelkart; Rudolf Zechner; Guenter Haemmerle
Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.
The Journal of biological chemistry 2013;288(14):9892-904.
2013: Nina M Pollak; Thomas Rülicke; Renate Schreiber; Martina Schweiger; Rudolf Zechner; Kathrin A Zierler; Robert Zimmermann; Christoph Heier; Doris Jaeger; Dagmar Kolb; Stephanie Kolleritsch; Manju Kumari; Achim Lass; Philipp Markolin; Gernot F Grabner; Guenter Haemmerle
Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.
Journal of lipid research 2013;54(4):1092-102.
2012: Maria Morak; Gerald N Rechberger; Gernot Riesenhuber; Hannes Schmidinger; Rudolf Zechner; Guenter Haemmerle; Manfred Kollroser; Florian Kronenberg; Albin Hermetter
Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues.
Molecular & cellular proteomics : MCP 2012;11(12):1777-89.
2012: Thomas O Eichmann; Robert V Farese; Joel T Haas; Manju Kumari; Achim Lass; Robert Zimmermann; Rudolf Zechner
Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.
The Journal of biological chemistry 2012;287(49):41446-57.
2012: Martina Schweiger; Rudolf Zechner; Robert Zimmermann; Elena Moser; Monika Oberer; Margret Paar; Franz P W Radner; Janina Brandis; Ines Cerk; Irina Cornaciu; Christina Eder; Gregor Gorkiewicz; Susanne Grond; Sander Kersten; Achim Lass
G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase.
Journal of lipid research 2012;53(11):2307-17.
2012: Chandramohan Chitraju; Jürgen Hartler; Harald Köfeler; Achim Lass; Gerhard G Thallinger; Martin Trötzmüller; Heimo Wolinski; Rudolf Zechner; Robert Zimmermann; Friedrich Spener
Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress.
Journal of lipid research 2012;53(10):2141-52.
2012: Manju Kumari; Achim Lass; Harald M Nagy; Monika Oberer; Margret Paar; Ashraf Y Rangrez; Gerald N Rechberger; Gabriele Schoiswohl; Sarah A Scott; Nuttaporn Wongsiriroj; Ruth Birner-Gruenberger; H Alex Brown; Chandramohan Chitraju; Irina Cornaciu; Sandra Eder; Guenter Haemmerle; Pavlina T Ivanova; Erin E Kershaw; Oskar Knittelfelder; Robert Zimmermann; Rudolf Zechner
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Cell metabolism 2012;15(5):691-702.
2012: Rudolf Zechner; Robert Zimmermann; Thomas O Eichmann; Guenter Haemmerle; Sepp D Kohlwein; Achim Lass; Frank Madeo
FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.
Cell metabolism 2012;15(3):279-91.
2011: Karoline Etschmaier; Alexandra Kober; Tatjana Becker; Anil Paul Chirackal Manavalan; Thomas O Eichmann; Michael Poeckl; Gerald N Rechberger; Monika Scholler; Rufina Schuligoi; Cornelia Schweinzer; Ingo E Streith; Carmen Tam-Amersdorfer; Rudolf Zechner; Robert Zimmermann; Ute Panzenboeck
Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.
Journal of neurochemistry 2011;119(5):1016-28.
2011: Kristina M Mueller; J Andrew Pospisilik; Michaela Schlederer; Guenther Schuetz; Veronika Sexl; Luigi Terracciano; Kay-Uwe Wagner; Rudolf Zechner; Leander Blaas; Emilio Casanova; Gerda Egger; David Engblom; Harald Esterbauer; Katrin Friedbichler; Guenter Haemmerle; Susanne Haindl; Peter Hasselblatt; Markus H Heim; Lukas Kenner; Jan-Wilhelm Kornfeld; Andrey V Kozlov; Dagmar Kratky; Richard Moriggl
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.
Hepatology (Baltimore, Md.) 2011;54(4):1398-409.
2011: Suman K Das; Clemens Diwoky; Sandra Eder; Gregor Gorkiewicz; Barbara Guertl; Guenter Haemmerle; Pooja Kumari; Silvia Schauer; Kuppusamy P Tamilarasan; Hannes Temmel; Michael Trauner; Paul Vesely; Rudolf Zechner; Robert Zimmermann; Gerald Hoefler
Adipose triglyceride lipase contributes to cancer-associated cachexia.
Science (New York, N.Y.) 2011;333(6039):233-8.
2011: Monika Oberer; Andras Boeszoermenyi; Harald M Nagy; Rudolf Zechner
Recent insights into the structure and function of comparative gene identification-58.
Current opinion in lipidology 2011;22(3):149-58.
2011: Ulrike Taschler; Franz P W Radner; Christoph Heier; Renate Schreiber; Martina Schweiger; Gabriele Schoiswohl; Karina Preiss-Landl; Doris Jaeger; Birgit Reiter; Harald C Koefeler; Jacek Wojciechowski; Christian Theussl; Josef M Penninger; Achim Lass; Guenter Haemmerle; Rudolf Zechner; Robert Zimmermann
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.
The Journal of biological chemistry 2011;286(20):17467-77.
2011: Franz Pw Radner; Susanne Grond; Guenter Haemmerle; Achim Lass; Rudolf Zechner
Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease.
Dermato-endocrinology 2011;3(2):77-83.
2011: Elma Aflaki; Branislav Radovic; Prakash G Chandak; Dagmar Kolb; Tobias Eisenberg; Julia Ring; Ismene Fertschai; Andreas Uellen; Heimo Wolinski; Sepp-Dieter Kohlwein; Rudolf Zechner; Sanja Levak-Frank; Wolfgang Sattler; Wolfgang F. Graier; Roland Malli; Frank Madeo; Dagmar Kratky
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
The Journal of biological chemistry 2011;286(9):7418-28.
2011: Irina Cornaciu; Catharina Ebner; Astrid Gruber; Achim Lass; Hanna Lindermuth; Harald M Nagy; Barbara Salzburger; Martina Schweiger; Rudolf Zechner; Robert Zimmermann; Andras Boeszoermenyi; Ines K Cerk; Monika Oberer
The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively.
PloS one 2011;6(10):e26349.
2011: Achim Lass; Robert Zimmermann; Monika Oberer; Rudolf Zechner
Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores.
Progress in lipid research 2011;50(1):14-27.
2010: Aliki Kosteli; Eiji Sugaru; Guenter Haemmerle; Jayne F Martin; Jason Lei; Rudolf Zechner; Anthony W Ferrante
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue.
The Journal of clinical investigation 2010;120(10):3466-79.
2010: Marlene Buchebner; Thomas Pfeifer; Nora Rathke; Prakash G Chandak; Achim Lass; Renate Schreiber; Adelheid Kratzer; Robert Zimmermann; Wolfgang Sattler; Harald Koefeler; Eleonore Fröhlich; Gerhard M Kostner; Ruth Birner-Gruenberger; Kyle P Chiang; Guenter Haemmerle; Rudolf Zechner; Sanja Levak-Frank; Benjamin Cravatt; Dagmar Kratky
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.
Journal of lipid research 2010;51(10):2896-908.
2010: Prakash G Chandak; Branislav Radovic; Elma Aflaki; Dagmar Kolb; Marlene Buchebner; Eleonore Fröhlich; Christoph Magnes; Frank Sinner; Guenter Haemmerle; Rudolf Zechner; Ira Tabas; Sanja Levak-Frank; Dagmar Kratky
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
The Journal of biological chemistry 2010;285(26):20192-201.
2010: Astrid Gruber; Irina Cornaciu; Achim Lass; Martina Schweiger; Margret Poeschl; Christina Eder; Manju Kumari; Gabriele Schoiswohl; Heimo Wolinski; Sepp D Kohlwein; Rudolf Zechner; Robert Zimmermann; Monika Oberer
The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
The Journal of biological chemistry 2010;285(16):12289-98.
2010: Franz P W Radner; Ingo E Streith; Gabriele Schoiswohl; Martina Schweiger; Manju Kumari; Thomas O Eichmann; Gerald Rechberger; Harald C Koefeler; Sandra Eder; Silvia Schauer; H Christian Theussl; Karina Preiss-Landl; Achim Lass; Robert Zimmermann; Gerald Hoefler; Rudolf Zechner; Guenter Haemmerle
Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
The Journal of biological chemistry 2010;285(10):7300-11.
2010: Gabriele Schoiswohl; Martina Schweiger; Renate Schreiber; Gregor Gorkiewicz; Karina Preiss-Landl; Ulrike Taschler; Kathrin A Zierler; Franz P W Radner; Thomas O Eichmann; Petra C Kienesberger; Sandra Eder; Achim Lass; Guenter Haemmerle; Thomas J Alsted; Bente Kiens; Gerald Hoefler; Rudolf Zechner; Robert Zimmermann
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids.
Journal of lipid research 2010;51(3):490-9.
2010: Stefan Coassin; Martina Schweiger; Anita Kloss-Brandstätter; Claudia Lamina; Margot Haun; Gertraud Erhart; Bernhard Paulweber; Yusof Rahman; Simon Olpin; Heimo Wolinski; Irina Cornaciu; Rudolf Zechner; Robert Zimmermann; Florian Kronenberg
Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population.
PLoS genetics 2010;6(12):e1001239.
2010: Gregor Gorkiewicz; Sabine Kienesberger; Caroline Schober; Sylvia R Scheicher; Christian Gülly; Rudolf Zechner; Ellen L Zechner
A genomic island defines subspecies-specific virulence features of the host-adapted pathogen Campylobacter fetus subsp. venerealis.
Journal of bacteriology 2010;192(2):502-17.
2009: Renate Schreiber; Ulrike Taschler; Heimo Wolinski; Andrea Seper; Stefanie N Tamegger; Maria Graf; Sepp D Kohlwein; Guenter Haemmerle; Robert Zimmermann; Rudolf Zechner; Achim Lass
Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver.
Journal of lipid research 2009;50(12):2514-23.
2009: Petra C Kienesberger; Daeho Lee; THOMAS CHACKO PULINILKUNNIL; Daniel S Brenner; Lingzhi Cai; Christoph Magnes; Harald C Koefeler; Ingo E Streith; Gerald N Rechberger; Guenter Haemmerle; Jeffrey S Flier; Rudolf Zechner; Young-Bum Kim; Erin E Kershaw
Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling.
The Journal of biological chemistry 2009;284(44):30218-29.
2009: Marie-Line Peyot; Claudiane Guay; Martin G Latour; Julien Lamontagne; Roxane Lussier; Marco Pineda; Neil B Ruderman; Guenter Haemmerle; Rudolf Zechner; Erik Joly; S R Murthy Madiraju; Vincent Poitout; Marc Prentki
Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion.
The Journal of biological chemistry 2009;284(25):16848-59.
2009: Robert Zimmermann; Achim Lass; Guenter Haemmerle; Rudolf Zechner
Fate of fat: the role of adipose triglyceride lipase in lipolysis.
Biochimica et biophysica acta 2009;1791(6):494-500.
2009: Monika Riederer; Wolfgang Erwa; Robert Zimmermann; Sasa Frank; Rudolf Zechner
Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine.
Atherosclerosis 2009;204(2):412-7.
2009: Petra C Kienesberger; Monika Oberer; Achim Lass; Rudolf Zechner
Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions.
Journal of lipid research 2009;50 Suppl():S63-8.
2008: Montserrat Pinent; Hubert Hackl; Thomas Rainer Burkard; Andreas Prokesch; Christine Papak; Marcel Scheideler; Günter Hämmerle; Rudolf Zechner; Zlatko Trajanoski; Juliane G Strauss
Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice.
Genomics 2008;92(1):26-32.
2008: Martina Schweiger; Gabriele Schoiswohl; Achim Lass; Franz P W Radner; Guenter Haemmerle; Roland Malli; Wolfgang F. Graier; Irina Cornaciu; Monika Oberer; Robert Salvayre; Judith Fischer; Rudolf Zechner; Robert Zimmermann
The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding.
The Journal of biological chemistry 2008;283(25):17211-20.
2008: Brendan N Reid; Gene P Ables; Oleg A Otlivanchik; Gabriele Schoiswohl; Rudolf Zechner; William S Blaner; Ira J Goldberg; Robert F Schwabe; Streamson Chua Jr.; Li-Shin Huang
Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.
The Journal of biological chemistry 2008;283(19):13087-99.
2008: Petra C Kienesberger; Achim Lass; Karina Preiss-Landl; Heimo Wolinski; Sepp D Kohlwein; Robert Zimmermann; Rudolf Zechner
Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase.
The Journal of biological chemistry 2008;283(9):5908-17.
2006: Martina Schweiger; Renate Schreiber; Guenter Haemmerle; Achim Lass; Christian Fledelius; Poul Jacobsen; Hans Tornqvist; Rudolf Zechner; Robert Zimmermann
Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism.
The Journal of biological chemistry 2006;281(52):40236-41.
2006: Marisa M O Tschernatsch; Bernhard Mlecnik; Zlatko Trajanoski; Rudolf Zechner; Robert Zimmermann
LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells.
Atherosclerosis 2006;189(2):310-7.
2006: Karin Osibow; Sasa Frank; Roland Malli; Rudolf Zechner; Wolfgang F. Graier
Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum.
The Biochemical journal 2006;396(1):173-82.
2006: Guenter Haemmerle; Achim Lass; Robert Zimmermann; Gregor Gorkiewicz; Carola Meyer; Jan Rozman; Gerhard Heldmaier; Robert Maier; Christian Theussl; Sandra Eder; Dagmar Kratky; Erwin F Wagner; Martin Klingenspor; Gerald Hoefler; Rudolf Zechner
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
Science (New York, N.Y.) 2006;312(5774):734-7.
2006: Achim Lass; Robert Zimmermann; Guenter Haemmerle; Monika Riederer; Gabriele Schoiswohl; Martina Schweiger; Petra Kienesberger; Juliane G Strauss; Gregor Gorkiewicz; Rudolf Zechner
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.
Cell metabolism 2006;3(5):309-19.
2006: Christoph F Kurat; klaus natter; Julia Petschnigg; Heimo Wolinski; Kim Scheuringer; Harald Scholz; Robert Zimmermann; Regina Leber; Rudolf Zechner; Sepp D Kohlwein
Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast.
The Journal of biological chemistry 2006;281(1):491-500.
2005: Marie L S Lindegaard; Gunilla Olivecrona; Christina Christoffersen; Dagmar Kratky; Jens Hannibal; Bodil Laub Petersen; Rudolf Zechner; Peter Damm; Lars B Nielsen
Endothelial and lipoprotein lipases in human and mouse placenta.
Journal of lipid research 2005;46(11):2339-46.
2005: Ruth Birner-Gruenberger; Heidrun Susani-Etzerodt; Markus Waldhuber; Gernot Riesenhuber; Hannes Schmidinger; Gerald Rechberger; Manfred Kollroser; Juliane G Strauss; Achim Lass; Robert Zimmermann; Guenter Haemmerle; Rudolf Zechner; Albin Hermetter
The lipolytic proteome of mouse adipose tissue.
Molecular & cellular proteomics : MCP 2005;4(11):1710-7.
2005: Rudolf Zechner; Juliane G Strauss; Guenter Haemmerle; Achim Lass; Robert Zimmermann
Lipolysis: pathway under construction.
Current opinion in lipidology 2005;16(3):333-40.
2005: Dagmar Kratky; Robert Zimmermann; Elke M Wagner; Juliane G Strauss; Weijun Jin; Gerhard Kostner; Guenter Haemmerle; Daniel J Rader; Rudolf Zechner
Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue.
The Journal of clinical investigation 2005;115(1):161-7.
2004: Robert Zimmermann; Juliane G Strauss; Guenter Haemmerle; Gabriele Schoiswohl; Ruth Birner-Gruenberger; Monika Riederer; Achim Lass; Georg Neuberger; Frank Eisenhaber; Albin Hermetter; Rudolf Zechner
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.
Science (New York, N.Y.) 2004;306(5700):1383-6.
2004: Gerhard Fritz; Elke M Wagner; Helmut Lindner; Wolfgang Hofmann; Rudolf Zechner; Otto Glatter
Dependence of lipoprotein-lipase-catalyzed triacylglycerol hydrolysis on droplet size of synthetic monodisperse emulsions measured with static light scattering.
Journal of colloid and interface science 2004;275(2):642-8.
2004: Ayanna Augustus; Hiroaki Yagyu; Guenter Haemmerle; André Bensadoun; Reeba K Vikramadithyan; So-Young Park; Jason K Kim; Rudolf Zechner; Ira J Goldberg
Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression.
The Journal of biological chemistry 2004;279(24):25050-7.
2004: Elke M Wagner; Dagmar Kratky; Guenter Haemmerle; Andelko Hrzenjak; Gerhard Kostner; Ernst Steyrer; Rudolf Zechner
Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis.
Journal of lipid research 2004;45(2):356-65.
2003: Robert Zimmermann; Guenter Haemmerle; Elke M Wagner; Juliane G Strauss; Dagmar Kratky; Rudolf Zechner
Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue.
Journal of lipid research 2003;44(11):2089-99.
2003: Peter J Voshol; Guenter Haemmerle; D Margriet Ouwens; Robert Zimmermann; Rudolf Zechner; Bas Teusink; J Antonie Maassen; Louis M Havekes; Johannes A Romijn
Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice.
Endocrinology 2003;144(8):3456-62.
2003: Guenter Haemmerle; Robert Zimmermann; Rudolf Zechner
Letting lipids go: hormone-sensitive lipase.
Current opinion in lipidology 2003;14(3):289-97.
2003: Gregor Gorkiewicz; Gebhard Feierl; Caroline Schober; Franz Dieber; Josef Köfer; Rudolf Zechner; Ellen L Zechner
Species-specific identification of campylobacters by partial 16S rRNA gene sequencing.
Journal of clinical microbiology 2003;41(6):2537-46.
2003: Juliane G Strauss; Marianne Hayn; Rudolf Zechner; Sanja Levak-Frank; Sasa Frank
Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in HepG2 cells.
The Biochemical journal 2003;371(Pt 3):981-8.
2003: Ouliana Ziouzenkova; Stéphane Perrey; Liana Asatryan; Juliana Hwang; Karen L Macnaul; David E Moller; Daniel J Rader; Alex Sevanian; Rudolf Zechner; Gerald Hoefler; Jorge Plutzky
Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2730-5.
2003: Christa Nöhammer; Friedrich Brunner; Gerald Wölkart; Philipp B Staber; Ernst Steyrer; Frank J Gonzalez; Rudolf Zechner; Gerald Hoefler
Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle.
Laboratory investigation; a journal of technical methods and pathology 2003;83(2):259-69.
2003: Friedrich Brunner; Robert Maier; Penelope Andrew; Gerald Wölkart; Rudolf Zechner; Bernd Mayer
Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase.
Cardiovascular research 2003;57(1):55-62.
2002: Juliane G Strauss; Robert Zimmermann; Andelko Hrzenjak; Yonggang Zhou; Dagmar Kratky; Sanja Levak-Frank; Gerhard Kostner; Rudolf Zechner; Sasa Frank
Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity.
The Biochemical journal 2002;368(Pt 1):69-79.
2002: Karina Preiss-Landl; Robert Zimmermann; Günter Hämmerle; Rudolf Zechner
Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism.
Current opinion in lipidology 2002;13(5):471-81.
2002: Daniel Goti; Zoltan Balazs; Ute Panzenboeck; Andelko Hrzenjak; Helga Reicher; Elke Wagner; Rudolf Zechner; Ernst Malle; Wolfgang Sattler
Effects of lipoprotein lipase on uptake and transcytosis of low density lipoprotein (LDL) and LDL-associated alpha-tocopherol in a porcine in vitro blood-brain barrier model.
The Journal of biological chemistry 2002;277(32):28537-44.
2002: Gregor Gorkiewicz; Gebhard Feierl; Rudolf Zechner; Ellen L Zechner
Transmission of Campylobacter hyointestinalis from a pig to a human.
Journal of clinical microbiology 2002;40(7):2601-5.
2002: Guenter Haemmerle; Robert Zimmermann; Juliane G Strauss; Dagmar Kratky; Monika Riederer; Gabriele Knipping; Rudolf Zechner
Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle.
The Journal of biological chemistry 2002;277(15):12946-52.
2002: Martin Merkel; Joerg Heeren; Wiebke Dudeck; Franz Rinninger; Herbert Radner; Jan L Breslow; Ira J Goldberg; Rudolf Zechner; Heiner Greten
Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake.
The Journal of biological chemistry 2002;277(9):7405-11.
2002: Guenter Haemmerle; Robert Zimmermann; Marianne Hayn; Christian Theussl; Georg Waeg; Elke Wagner; Wolfgang Sattler; Thomas M Magin; Erwin F Wagner; Rudolf Zechner
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis.
The Journal of biological chemistry 2002;277(7):4806-15.
2002: Victor E Esenabhalu; Mirza Cerimagic; Roland Malli; Karin Osibow; Sanja Levak-Frank; Maud Frieden; Wolfgang Sattler; Gerhard Kostner; Rudolf Zechner; Wolfgang F. Graier
Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice.
British journal of pharmacology 2002;135(1):143-54.
2001: Friedrich Brunner; Penelope Andrew; Gerald Wölkart; Rudolf Zechner; Bernd Mayer
Myocardial contractile function and heart rate in mice with myocyte-specific overexpression of endothelial nitric oxide synthase.
Circulation 2001;104(25):3097-102.
2001: Peter J Voshol; Miek C Jong; Vivian E H Dahlmans; Dagmar Kratky; Sanja Levak-Frank; Rudolf Zechner; Johannes A Romijn; Louis M Havekes
In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake.
Diabetes 2001;50(11):2585-90.
2001: Juliane G Strauss; Sasa Frank; Dagmar Kratky; G Hämmerle; Andelko Hrzenjak; Gabriele Knipping; A von Eckardstein; Gerhard Kostner; Rudolf Zechner
Adenovirus-mediated rescue of lipoprotein lipase-deficient mice. Lipolysis of triglyceride-rich lipoproteins is essential for high density lipoprotein maturation in mice.
The Journal of biological chemistry 2001;276(39):36083-90.
2001: Robert Zimmermann; U Panzenböck; Andrea Wintersperger; Sanja Levak-Frank; Wolfgang F. Graier; Otto Glatter; G Fritz; Gerhard Kostner; Rudolf Zechner
Lipoprotein lipase mediates the uptake of glycated LDL in fibroblasts, endothelial cells, and macrophages.
Diabetes 2001;50(7):1643-53.
2001: Dagmar Kratky; Juliane G Strauss; Rudolf Zechner
Tissue-specific activity of lipoprotein lipase in skeletal muscle regulates the expression of uncoupling protein 3 in transgenic mouse models.
The Biochemical journal 2001;355(Pt 3):647-52.
2000: Rudolf Zechner; J Strauss; Sasa Frank; Elke Wagner; W Hofmann; Dagmar Kratky; M Hiden; Sanja Levak-Frank
The role of lipoprotein lipase in adipose tissue development and metabolism.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24 Suppl 4():S53-6.
2000: Barbara Guertl; Alfred Beham; Rudolf Zechner; Heinz Stammberger; Gerald Hoefler
Nasopharyngeal angiofibroma: an APC-gene-associated tumor?
Human pathology 2000;31(11):1411-3.
2000: Miranda van Eck; Robert Zimmermann; Pieter Groot; Rudolf Zechner; Theo Van berkel
Role of macrophage-derived lipoprotein lipase in lipoprotein metabolism and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(9):E53-62.
2000: S Prattes; Gerd Hörl; Astrid Hammer; Astrid Blaschitz; Wolfgang F. Graier; Wolfgang Sattler; Rudolf Zechner; Ernst Steyrer
Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures.
Journal of cell science 2000;113 ( Pt 17)():2977-89.
2000: S Meraji; Peter M Abuja; Marianne Hayn; Gerhard Kostner; R Morris; S Oraii; Franz Tatzber; Willibald Wonisch; Rudolf Zechner; Fred Gey
Relationship between classic risk factors, plasma antioxidants and indicators of oxidant stress in angina pectoris (AP) in Tehran.
Atherosclerosis 2000;150(2):403-12.
2000: Robert Zimmermann; Peter Sartipy; R Winkler; Rudolf Zechner; Eva Hurt-Camejo; Gerhard Kostner
Endogenously produced glycosaminoglycans affecting the release of lipoprotein lipase from macrophages and the interaction with lipoproteins.
Biochimica et biophysica acta 2000;1484(2-3):316-24.
2000: C Nöhammer; Yosuf El Shabrawi; Silvia Schauer; M Hiden; J Berger; S Forss-Petter; E Winter; Robert Eferl; Rudolf Zechner; Gerald Hoefler
cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase.
European journal of biochemistry / FEBS 2000;267(4):1254-60.
1999: Xiaosong Wang; Joachim Greilberger; Sanja Levak-Frank; Robert Zimmermann; Rudolf Zechner; Günther Jürgens
Endogenously produced lipoprotein lipase enhances the binding and cell association of native, mildly oxidized and moderately oxidized low-density lipoprotein in mouse peritoneal macrophages.
The Biochemical journal 1999;343 Pt 2():347-53.
1999: Sanja Levak-Frank; W Hofmann; PH Weinstock; Herbert Radner; Wolfgang Sattler; Jan L Breslow; Rudolf Zechner
Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and high-density lipoprotein-cholesterol levels.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3165-70.
1997: PH Weinstock; Sanja Levak-Frank; Lisa Cooper Hudgins; Herbert Radner; Jeffrey M Friedman; Rudolf Zechner; Jan L Breslow
Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10261-6.
1997: Sanja Levak-Frank; PH Weinstock; T Hayek; Roy B Verdery; W Hofmann; R Ramakrishnan; Wolfgang Sattler; Jan L Breslow; Rudolf Zechner
Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma.
The Journal of biological chemistry 1997;272(27):17182-90.
1997: Rudolf Zechner
The tissue-specific expression of lipoprotein lipase: implications for energy and lipoprotein metabolism.
Current opinion in lipidology 1997;8(2):77-88.
1997: Gerald Hoefler; C Noehammer; Sanja Levak-Frank; Yosuf El Shabrawi; Silvia Schauer; Rudolf Zechner; Herbert Radner
Muscle-specific overexpression of human lipoprotein lipase in mice causes increased intracellular free fatty acids and induction of peroxisomal enzymes.
Biochimie 1997;79(2-3):163-8.
1997: Ute Panzenboeck; A Wintersberger; Sanja Levak-Frank; Robert Zimmermann; Rudolf Zechner; Gerhard Kostner; Ernst Malle; Wolfgang Sattler
Implications of endogenous and exogenous lipoprotein lipase for the selective uptake of HDL3-associated cholesteryl esters by mouse peritoneal macrophages.
Journal of lipid research 1997;38(2):239-53.
1996: Wolfgang Sattler; Sanja Levak-Frank; Herbert Radner; Gerhard Kostner; Rudolf Zechner
Muscle-specific overexpression of lipoprotein lipase in transgenic mice results in increased alpha-tocopherol levels in skeletal muscle.
The Biochemical journal 1996;318 ( Pt 1)():15-9.
1996: I Wicher; Wolfgang Sattler; A Ibovnik; Gerhard Kostner; Rudolf Zechner; Ernst Malle
Quantification of lipoprotein lipase (LPL) by dissociation-enhanced lanthanide fluorescence immunoassay. Comparison of immunoreactivity of LPL mass and enzyme activity of LPL.
Journal of immunological methods 1996;192(1-2):1-11.
1996: Ernst Steyrer; Sasa Frank; S Durovic; Rudolf Zechner; Gerhard Kostner
LDL structure and Lp(a) formation: the role of lecithin:cholesterol acyltransferase.
Zeitschrift für Gastroenterologie 1996;34 Suppl 3():39-40.
1996: Sasa Frank; S Durovic; Rudolf Zechner; Gerhard Kostner
Biosynthesis of lipoprotein-a from transfected cells.
Zeitschrift für Gastroenterologie 1996;34 Suppl 3():33-5.
1996: M Duque; M Graupner; H Stütz; I Wicher; Rudolf Zechner; Fritz Paltauf; Albin Hermetter
New fluorogenic triacylglycerol analogs as substrates for the determination and chiral discrimination of lipase activities.
Journal of lipid research 1996;37(4):868-76.
1995: PH Weinstock; Charles L Bisgaier; K Aalto-Setälä; Herbert Radner; Rajasekhar Ramakrishnan; Sanja Levak-Frank; AD Essenburg; Rudolf Zechner; Jan L Breslow
Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes.
The Journal of clinical investigation 1995;96(6):2555-68.
1995: Sanja Levak-Frank; Herbert Radner; A Walsh; Rudolf Stollberger; Gabriele Knipping; Gerald Hoefler; Wolfgang Sattler; PH Weinstock; Jan L Breslow; Rudolf Zechner
Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice.
The Journal of clinical investigation 1995;96(2):976-86.
1995: Ernst Steyrer; S Haubenwallner; G Hörl; W Giessauf; Gerhard Kostner; Rudolf Zechner
A single G to A nucleotide transition in exon IV of the lecithin: cholesterol acyltransferase (LCAT) gene results in an Arg140 to His substitution and causes LCAT-deficiency.
Human genetics 1995;96(1):105-9.
1994: S Durovic; Sasa Frank; Hubert Scharnagl; M W Baumstark; Rudolf Zechner; W März; Gerhard Kostner
Decreased binding of apolipoprotein (a) to familial defective apolipoprotein B-100 (Arg3500-->Gln). A study of the assembly of recombinant apolipoprotein (a) with mutant low density lipoproteins.
The Journal of biological chemistry 1994;269(48):30320-5.
1994: Ernst Steyrer; S Durovic; Sasa Frank; W Giessauf; A Burger; Hans Dieplinger; Rudolf Zechner; Gerhard Kostner
The role of lecithin: cholesterol acyltransferase for lipoprotein (a) assembly. Structural integrity of low density lipoproteins is a prerequisite for Lp(a) formation in human plasma.
The Journal of clinical investigation 1994;94(6):2330-40.
1994: Gerald Hoefler; M Forstner; M C McGuinness; W Hulla; M Hiden; Peter Krisper; Lukas Kenner; T Ried; Christoph Lengauer; Rudolf Zechner
cDNA cloning of the human peroxisomal enoyl-CoA hydratase: 3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme and localization to chromosome 3q26.3-3q28: a free left Alu Arm is inserted in the 3' noncoding region.
Genomics 1994;19(1):60-7.
1993: S Haubenwallner; G Hörl; N S Shachter; E Presta; S K Fried; Gerald Hoefler; Gerhard Kostner; Jan L Breslow; Rudolf Zechner
A novel missense mutation in the gene for lipoprotein lipase resulting in a highly conservative amino acid substitution (Asp180-->Glu) causes familial chylomicronemia (type I hyperlipoproteinemia).
Genomics 1993;18(2):392-6.
1993: A Birchbauer; Gabriele Knipping; B Juritsch; H Aschauer; Rudolf Zechner
Characterization of the apolipoprotein AI and CIII genes in the domestic pig.
Genomics 1993;15(3):643-52.
1993: S K Fried; B Appel; Rudolf Zechner
Interleukin 1 alpha decreases the synthesis and activity of lipoprotein lipase in human adipose tissue.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1993;25(2):129-30.
1992: K Aalto-Setälä; E A Fisher; X Chen; T Chajek-Shaul; T Hayek; Rudolf Zechner; A Walsh; Rajasekhar Ramakrishnan; Henry N Ginsberg; Jan L Breslow
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.
The Journal of clinical investigation 1992;90(5):1889-900.
1991: Rudolf Zechner; T C Newman; E Steiner; Jan L Breslow
The structure of the mouse lipoprotein lipase gene: a B1 repetitive element is inserted into the 3' untranslated region of the mRNA.
Genomics 1991;11(1):62-76.
1991: Rudolf Zechner; R Moser; T C Newman; S K Fried; Jan L Breslow
Apolipoprotein E gene expression in mouse 3T3-L1 adipocytes and human adipose tissue and its regulation by differentiation and lipid content.
The Journal of biological chemistry 1991;266(16):10583-8.
1990: Rudolf Zechner
Rapid and simple isolation procedure for lipoprotein lipase from human milk.
Biochimica et biophysica acta 1990;1044(1):20-5.
1989: S K Fried; Rudolf Zechner
Cachectin/tumor necrosis factor decreases human adipose tissue lipoprotein lipase mRNA levels, synthesis, and activity.
Journal of lipid research 1989;30(12):1917-23.
1988: M S Weintraub; Rudolf Zechner; A Brown; S Eisenberg; Jan L Breslow
Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.
The Journal of clinical investigation 1988;82(6):1884-93.
1988: Rudolf Zechner; T C Newman; B Sherry; A Cerami; Jan L Breslow
Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotein lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes.
Molecular and cellular biology 1988;8(6):2394-401.
1987: Rudolf Zechner; Hans Dieplinger; Ernst Steyrer; J Groener; D Calvert; Gerhard Kostner
In vitro formation of HDL-2 from HDL-3 and triacylglycerol-rich lipoproteins by the action of lecithin:cholesterol acyltransferase and cholesterol ester transfer protein.
Biochimica et biophysica acta 1987;918(1):27-35.
1987: Gerhard Kostner; Gabriele Knipping; J E Groener; Rudolf Zechner; Hans Dieplinger
The role of LCAT and cholesteryl ester transfer proteins for the HDL and LDL structure and metabolism.
Advances in experimental medicine and biology 1987;210():79-86.
1986: Gabriele Knipping; A Birchbauer; Ernst Steyrer; J Groener; Rudolf Zechner; Gerhard Kostner
Studies on the substrate specificity of human and pig lecithin: cholesterol acyltransferase: role of low-density lipoproteins.
Biochemistry 1986;25(18):5242-9.
1985: Gabriele Knipping; Rudolf Zechner; Gerhard Kostner; A Holasek
Factors affecting the conversion of high-density lipoproteins: experiments with pig and human plasma.
Biochimica et biophysica acta 1985;835(2):244-52.
1985: G M Kostner; F Krempler; Hans Dieplinger; Rudolf Zechner; I Teubl; F Sandhofer
Altered metabolism of low density lipoprotein in humans after prolonged incubation in plasma.
Clinical science (London, England : 1979) 1985;68(4):411-8.
1985: Hans Dieplinger; Rudolf Zechner; G M Kostner
The in vitro formation of HDL2 during the action of LCAT: the role of triglyceride-rich lipoproteins.
Journal of lipid research 1985;26(3):273-82.
1985: G M Kostner; H Wurm; Rudolf Zechner; E Pilger; Hans Dieplinger
Apolipoproteins: significance for lipid metabolism and for diagnosis of atherosclerotic disease.
Progress in clinical and biological research 1985;188():67-77.
1985: G M Kostner; B Hadorn; A Roscher; Rudolf Zechner
Plasma lipids and lipoproteins of a patient with cholesteryl ester storage disease.
Journal of inherited metabolic disease 1985;8(1):9-12.
1984: Rudolf Zechner; G M Kostner; Hans Dieplinger; Gábor Degovics; Peter Laggner
In vitro modification of the chemical composition of human plasma low density lipoproteins: effects of morphology and thermal properties.
Chemistry and physics of lipids 1984;36(2):111-9.
1984: Rudolf Zechner; Hans Dieplinger; A Roscher; G M Kostner
The low-density-lipoprotein pathway of native and chemically modified low-density lipoproteins isolated from plasma incubated in vitro.
The Biochemical journal 1984;224(2):569-76.
1984: Gabriele Knipping; Ernst Steyrer; Rudolf Zechner; A Holasek
Isolation and characterization of polymorphic forms of porcine apoC-II by chromatofocusing.
Journal of lipid research 1984;25(1):86-91.
1982: Rudolf Zechner; Hans Dieplinger; A Roscher; F Krempler; G M Kostner
The role of lecithin:cholesterol acyltransferase for the low density lipoprotein composition and specific binding to the B receptor.
Biochimica et biophysica acta 1982;712(2):433-5.