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Roderick Bronson

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Christian Bowman-Colin; Roderick T Bronson; Samuel Bunting; Hong Cai; Xixi Chen; Aedin C Culhane; Rinske Drost; Laura Fineman; Jos Jonkers; Chryssa Kanellopoulou; Christiaan Klijn; Andre Nussenzweig; Scott J Rodig; Bing Xia; Peter Bouwman; David M Livingston
Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Erin M Coffee; Veerle de Vriendt; Jeffrey A Engelman; Anthony C Faber; Gautam Goel; Roderick T Bronson; Lily Keung; Eric S Martin; Jatin Roper; Mark J Sinnamon; Sabine Tejpar; Loredana Vecchione; Wei Vivian Wang; Barbara J Weinstein; Ramnik J Xavier; Kenneth E Hung
Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer.
Hee Jung Park; Roderick T Bronson; Wayne N Frankel; Mingi Hong; Mark A Israel; Kyuson Yun
Elevated Id2 expression results in precocious neural stem cell depletion and abnormal brain development.

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All Publications

2013: Christian Bowman-Colin; Roderick T Bronson; Samuel Bunting; Hong Cai; Xixi Chen; Aedin C Culhane; Rinske Drost; Laura Fineman; Jos Jonkers; Chryssa Kanellopoulou; Christiaan Klijn; Andre Nussenzweig; Scott J Rodig; Bing Xia; Peter Bouwman; David M Livingston
Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(21):8632-7.
2013: Erin M Coffee; Veerle de Vriendt; Jeffrey A Engelman; Anthony C Faber; Gautam Goel; Roderick T Bronson; Lily Keung; Eric S Martin; Jatin Roper; Mark J Sinnamon; Sabine Tejpar; Loredana Vecchione; Wei Vivian Wang; Barbara J Weinstein; Ramnik J Xavier; Kenneth E Hung
Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(10):2688-98.
2013: Hee Jung Park; Roderick T Bronson; Wayne N Frankel; Mingi Hong; Mark A Israel; Kyuson Yun
Elevated Id2 expression results in precocious neural stem cell depletion and abnormal brain development.
Stem cells (Dayton, Ohio) 2013;31(5):1010-21.
2013: Marina V Kasaikina; Sergey N Novoselov; Ulrich Schweizer; Sandra Seeher; Anton A Turanov; Andrei Avanesov; Roderick T Bronson; Bradley A Carlson; Dolph L Hatfield; Vadim N Gladyshev
Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis.
Carcinogenesis 2013;34(5):1089-95.
2013: Peter C W Lee; Bruce A Yankner; Liviu Aron; Roderick T Bronson; Jean-Cosme Dodart; Lydia W Finley; Marcia Haigis; J Wade Harper
Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.
Molecular cell 2013;50(2):172-84.
2013: Jennifer A Calvo; David C Christiani; Lindsey W Eichinger; Iny Jhun; Annabelle Lake; Prajit Limsirichai; Lisiane Meira; Catherine A Moroski-Erkul; Roderick T Bronson; Dharini Shah; Leona D Samson
Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1.
PLoS genetics 2013;9(4):e1003413.
2013: Esther Baena; Roderick T Bronson; Yuko Fujiwara; Kimberly Glass; Frank J Godinho; Melanie J Hamblen; Jonghwan Kim; Douglas E Linn; Massimo Loda; Lorelei A Mucci; Minh Nguyen; Stuart H Orkin; Zhen Shao; Guo-Cheng Yuan; Xin Zhang; Zhe Li
ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.
Genes & development 2013;27(6):683-98.
2013: Ophélia Maertens; Richard Marais; Martin McMahon; Ludwine MESSIAEN; Jennifer A Wargo; Zachary A Cooper; Keith Flaherty; Dennie T Frederick; Scott Granter; Pablo Hollstein; Bryan Johnson; Roderick T Bronson; Karen Cichowski
Elucidating distinct roles for NF1 in melanomagenesis.
Cancer discovery 2013;3(3):338-49.
2012: Chengkai Dai; Hyoungtae Kwon; Roderick T Bronson; Junxia Cao; Sandro Santagata; Jiayuan Shi; Zijian Tang; Luke Whitesell; Susan Lindquist
Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.
The Journal of clinical investigation 2012;122(10):3742-54.
2012: Jinzhong Qin; Sridhar Ramaswamy; Warren A Whyte; Richard A Young; Schahram Akbarian; Endre Anderssen; Effie Apostolou; Roderick T Bronson; Hsu-Hsin Chen; Konrad Hochedlinger; Hanno Hock
The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development.
Cell stem cell 2012;11(3):319-32.
2012: MARTIN OUDEGA; Andres Hurtado; Donna Avison; Roderick T Bronson; William J Buchser; Owen Y Chao; Barbara Grimpe
Systemic administration of a deoxyribozyme to xylosyltransferase-1 mRNA promotes recovery after a spinal cord contusion injury.
Experimental neurology 2012;237(1):170-9.
2012: Hyun Jung Jun; Forest White; Roderick T Bronson; Sebastien de Feraudy; Hannah Johnson; Alain Charest
The oncogenic lung cancer fusion kinase CD74-ROS activates a novel invasiveness pathway through E-Syt1 phosphorylation.
Cancer research 2012;72(15):3764-74.
2012: H J Jun; J Lessard; Rolf Pfannl; A Raval; F White; C A Whittaker; S Woolfenden; H Zhu; Jaime Acquaviva; Abraham Boskovitz; Roderick T Bronson; D Chi; David E Housman; L Iyer; Al Charest
Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme.
Oncogene 2012;31(25):3039-50.
2012: Suchithra Menon; Justin Nicholatos; Jessica L Yecies; Hui H Zhang; Roderick T Bronson; Eylul Harputlugil; Jessica J Howell; David J Kwiatkowski; Brendan D Manning
Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice.
Science signaling 2012;5(217):ra24.
2012: Jianing Liu; Christine Miller; Michael D Milsom; Roderick T Bronson; Simone Hettmer; Inga Hofmann; Frederic Hua; Amy J Wagers
Induction of histiocytic sarcoma in mouse skeletal muscle.
PloS one 2012;7(8):e44044.
2012: Xianjun Zhu; Roderick T Bronson; Wilhelmine N de Vries; Richard T Libby; Kevin Seburn; Richard S Smith; Dana L Wright; Simon W M John
Mutations in a P-type ATPase gene cause axonal degeneration.
PLoS genetics 2012;8(8):e1002853.
2012: Jennifer M Ritchie; Haopeng Rui; Xiaohui Zhou; Roderick T Bronson; Brigid M Davis; Tetsuya Iida; Susuma Ito; Toshio Kodoma; Matthew K Waldor
Inflammation and disintegration of intestinal villi in an experimental model for Vibrio parahaemolyticus-induced diarrhea.
PLoS pathogens 2012;8(3):e1002593.
2011: Jaime Acquaviva; Abraham Boskovitz; Roderick T Bronson; Melissa Donovan; David E Housman; Hyun Jung Jun; Julie Lessard; Rolf Pfannl; Ami Raval; Rolando Ruiz; Charles A Whittaker; Steve Woolfenden; Haihao Zhu; Al Charest
Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation.
Cancer research 2011;71(23):7198-206.
2011: Jennifer M Ritchie; Dean Scholl; Steven R Williams; Roderick T Bronson; Brigid M Davis; Dana Gebhart; Jennifer L Greenwich; David Martin; Matthew K Waldor
An Escherichia coli O157-specific engineered pyocin prevents and ameliorates infection by E. coli O157:H7 in an animal model of diarrheal disease.
Antimicrobial agents and chemotherapy 2011;55(12):5469-74.
2011: Eric D Ciappio; Roderick T Bronson; Ryan S Brooks; Zhenhua Liu; Joel B Mason; Jimmy W Crott
Maternal B vitamin supplementation from preconception through weaning suppresses intestinal tumorigenesis in Apc1638N mouse offspring.
Gut 2011;60(12):1695-702.
2011: Juliana M Chan; Chester L Drum; Gershon Golomb; Robert Langer; June-Wha Rhee; Roderick T Bronson; Omid C Farokhzad
In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(48):19347-52.
2011: June Goto; Frances E Jensen; Steven G Kernie; Peter Klein; Stefanie Anderl; Roderick T Bronson; Jennifer A Chan; Yvonne I Chekaluk; Alessia Di Nardo; Izabela Malinowska Kolodziej; Wei Qin; Mustafa Sahin; Delia M Talos; Harry V Vinters; David J Kwiatkowski
Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(45):E1070-9.
2011: Thomas De Raedt; Marcia C Haigis; Seung Min Jeong; Raghu Kalluri; Valerie Lebleu; Danan Li; Kay F Macleod; Ophélia Maertens; Clare F Malone; Brendan D Manning; Emmanuel Normant; Zandra Walton; Kwok-Kin Wong; Jessica L Yecies; Roderick T Bronson; Yimei Chen; Karen Cichowski
Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.
Cancer cell 2011;20(3):400-13.
2011: Wenchu Lin; Jiayun Liu; Zongzhi Liu; Matthew Meyerson; Yoji Andrew MINAMISHIMA; Stuart H Orkin; Scott Rodig; Xiaohua Shen; Sabina Signoretti; David P Tuck; Hideo Watanabe; Elizaveta V. Benevolenskay; Michael L Beshiri; Lauren P Blair; Roderick T Bronson; Jian Cao; Andrew D Cherniack; Joshua Francis; Yuko Fujiwara; Christoph Geisen; Chiara Grisanzio; William G Kaelin; Dan Kawamori; Rohit N Kulkarni; Qing Zhang; Mike R Zou; Qin Yan
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(33):13379-86.
2011: Chun Liu; Robert M Russell; Roderick T Bronson; Xiang-Dong Wang
β-Cryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage, and squamous metaplasia in ferrets.
Cancer prevention research (Philadelphia, Pa.) 2011;4(8):1255-66.
2011: Chong Liu; Liqun Luo; Michael R Miller; Akiko Nishiyama; Jonathan C Sage; Roel G W Verhaak; Hannes Vogel; Roderick T Bronson; Oded Foreman; Simon Hippenmeyer; Hui Zong
Mosaic analysis with double markers reveals tumor cell of origin in glioma.
Cell 2011;146(2):209-21.
2011: Alison L Dooley; Levi A Garraway; Shantanu Banerji; Jordi Barretina; Roderick T Bronson; Derek Y Chiang; Denise Crowley; Talya L Dayton; Matthew Meyerson; Stephanie Senna; Eric L Snyder; Nicolas Stransky; Charles A Whittaker; Monte M Winslow; Tyler Jacks
Nuclear factor I/B is an oncogene in small cell lung cancer.
Genes & development 2011;25(14):1470-5.
2011: Neil Johnson; Danan Li; Yu-Chen Li; Lisa A Moreau; David R Newell; Scott J Rodig; Roderick T Bronson; Katherine A Cheng; Nicola J Curtin; Alan D D'Andrea; Huw D Thomas; Christine Unitt; Zandra E Walton; Kwok-Kin Wong; Geoffrey I Shapiro
Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.
Nature medicine 2011;17(7):875-82.
2011: Monte M Winslow; Talya L Dayton; Roel G W Verhaak; Caroline Kim-Kiselak; Eric L Snyder; David M Feldser; Diana D Hubbard; Michel J DuPage; Charles A Whittaker; Sebastian Hoersch; Stephanie Yoon; Denise Crowley; Roderick T Bronson; Derek Y Chiang; Matthew Meyerson; Tyler Jacks
Suppression of lung adenocarcinoma progression by Nkx2-1.
Nature 2011;473(7345):101-4.
2011: Stine Rasmussen; Jaime Imitola; Angel Ayuso-Sacido; Yue Wang; Sarah C Starossom; Pia Kivisäkk; Bing Zhu; Morten Meyer; Roderick T Bronson; Jose Manuel Garcia-Verdugo; Samia J Khoury
Reversible neural stem cell niche dysfunction in a model of multiple sclerosis.
Annals of neurology 2011;69(5):878-91.
2011: Katharine Ellwood-Yen; Heike Keilhack; Kaiko Kunii; Brian Dolinski; Yamicia Connor; Kun Hu; Kumiko Nagashima; Erin O'Hare; Yusuf Erkul; Alessandra Di Bacco; Diana Gargano; Nirah H Shomer; Minilik Angagaw; Erica Leccese; Paula Andrade; Melissa Hurd; Myung K Shin; Thomas F Vogt; Alan Northrup; Ekaterina V Bobkova; Shailaja Kasibhatla; Roderick T Bronson; Martin L Scott; Giulio Draetta; Victoria Richon; Nancy Kohl; Peter Blume-Jensen; Jannik N Andersen; Manfred Kraus
PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.
Cancer research 2011;71(8):3052-65.
2011: Huijuan Lv; Evis Havari; Sheena Pinto; Raju V S R K Gottumukkala; Lizbeth Cornivelli; Khadir Raddassi; Takashi Matsui; Anthony Rosenzweig; Roderick T Bronson; Ross Smith; Anne L Fletcher; Shannon J Turley; Kai Wucherpfennig; Bruno Kyewski; Myra A Lipes
Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans.
The Journal of clinical investigation 2011;121(4):1561-73.
2011: Jatin Roper; Mark J Sinnamon; Wei Vivian Wang; Roderick T Bronson; Peng-Chieh Chen; Wei Chen; Erin M Coffee; Lydia Lee; Eric S Martin; Larissa Georgeon Richard; Michael P Richardson; Kenneth E Hung
The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.
PloS one 2011;6(9):e25132.
2011: Ok S Shin; Masato Suzuki; Vincent C Tam; Matthew K Waldor; Roderick T Bronson; Jennifer M Ritchie; John J Mekalanos
Type III secretion is essential for the rapidly fatal diarrheal disease caused by non-O1, non-O139 Vibrio cholerae.
mBio 2011;2(3):e00106-11.
2011: Tanja Petnicki-Ocwieja; Alicia S DeFrancesco; Erin Chung; Courtney T Darcy; Roderick T Bronson; Koichi S Kobayashi; Linden T Hu
Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance.
PloS one 2011;6(2):e17414.
2010: Bjoern Schwer; Bjoern Schumacher; David Lombard; Cuiying Xiao; Martin V Kurtev; Jun Gao; Jennifer I Schneider; Hua Chai; Roderick T Bronson; Li-Huei Tsai; Chu-Xia Deng; Frederick W Alt
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(50):21790-4.
2010: Kristy R Kutanzi; Igor Koturbash; Roderick T Bronson; Igor P Pogribny; Olga Kovalchuk
Imbalance between apoptosis and cell proliferation during early stages of mammary gland carcinogenesis in ACI rats.
Mutation research 2010;694(1-2):1-6.
2010: Weiguo Hu; Richard Jin; Jinyan Zhang; Tao You; Zhihai Peng; Xiaowen Ge; Roderick T Bronson; Jose A Halperin; Joseph Loscalzo; Xuebin Qin
The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model.
Blood 2010;116(9):1613-22.
2010: Haihao Zhu; Steve Woolfenden; Roderick T Bronson; Zahara M Jaffer; Sofia Barluenga; Nicolas Winssinger; Allan E Rubenstein; Ruihong Chen; Al Charest
The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme.
Molecular cancer therapeutics 2010;9(9):2618-26.
2010: Yunli Zhou; Pornsuk Cheunsuchon; Yuki Nakayama; Michael W Lawlor; Ying Zhong; Kimberley A Rice; Li Zhang; Xun Zhang; Francesca E Gordon; Hart G W Lidov; Roderick T Bronson; Anne Klibanski
Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene.
Development (Cambridge, England) 2010;137(16):2643-52.
2010: Arjan van der Flier; Kwabena Badu-Nkansah; Charles A Whittaker; Denise Crowley; Roderick T Bronson; Adam Lacy-Hulbert; Richard O Hynes
Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development.
Development (Cambridge, England) 2010;137(14):2439-49.
2010: Cullen M Taniguchi; Jonathon Winnay; Tatsuya Kondo; Roderick T Bronson; Alexander R Guimaraes; José O Alemán; Ji Luo; Gregory Stephanopoulos; Ralph Weissleder; Lewis C Cantley; C Ronald Kahn
The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Cancer research 2010;70(13):5305-15.
2010: Tobias L Freitag; Candace Cham; Hsiang-Hsuan Sung; Georg F Beilhack; Ivana Durinovic-Belló; Salil D Patel; Roderick T Bronson; Detlef Schuppan; Grete Sønderstrup
Human risk allele HLA-DRB1*0405 predisposes class II transgenic Ab0 NOD mice to autoimmune pancreatitis.
Gastroenterology 2010;139(1):281-91.
2010: Raimon Duran-Struuck; Patricia S Cho; Alexander G S Teague; Brian Fishman; Aaron S Fishman; John S Hanekamp; Shannon G Moran; Krzysztof J Wikiel; Kelly K Ferguson; Diana P Lo; Mike Duggan; J Scott Arn; Bob Billiter; Ben Horner; Stuart Houser; Beow Yong Yeap; Susan V Westmoreland; Thomas R Spitzer; Isabel M McMorrow; David H Sachs; Roderick T Bronson; Christene A Huang
Myelogenous leukemia in adult inbred MHC-defined miniature swine: a model for human myeloid leukemias.
Veterinary immunology and immunopathology 2010;135(3-4):243-56.
2010: Christine A Denny; Karie A Heinecke; Youngho P Kim; Rena C Baek; Katrina S Loh; Terry D Butters; Roderick T Bronson; Frances M Platt; Thomas N Seyfried
Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.
Journal of neurochemistry 2010;113(6):1525-35.
2010: Christopher D Pritchard; Jonathan R Slotkin; Dou Yu; Haining Dai; Matthew S Lawrence; Roderick T Bronson; Francis M Reynolds; Yang D Teng; Eric J Woodard; Robert S Langer
Establishing a model spinal cord injury in the African green monkey for the preclinical evaluation of biodegradable polymer scaffolds seeded with human neural stem cells.
Journal of neuroscience methods 2010;188(2):258-69.
2010: Trudy Oliver; Kim L Mercer; Leanne C Sayles; James R Burke; Diana Mendus; Katherine S Lovejoy; Mei-Hsin Cheng; Aravind Subramanian; David Mu; Scott Powers; Denise Crowley; Roderick T Bronson; Charles A Whittaker; Arjun Bhutkar; Stephen J Lippard; Todd R Golub; Juergen Thomale; Tyler Jacks; Eric A. Sweet-Cordero
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.
Genes & development 2010;24(8):837-52.
2010: Jennifer M Ritchie; Haopeng Rui; Roderick T Bronson; Matthew K Waldor
Back to the future: studying cholera pathogenesis using infant rabbits.
mBio 2010;1(1):.
2010: Lei Xu; Shahinoor Begum; Marc Barry; Denise Crowley; Liquan Yang; Roderick T Bronson; Richard O Hynes
GPR56 plays varying roles in endogenous cancer progression.
Clinical & experimental metastasis 2010;27(4):241-9.
2010: A F Cheung; A M Carter; K K Kostova; J F Woodruff; D Crowley; Roderick T Bronson; Kevin Haigis; Tyler Jacks
Complete deletion of Apc results in severe polyposis in mice.
Oncogene 2010;29(12):1857-64.
2010: Gongxiong Wu; Ting Chen; Aliakbar Shahsafaei; Weiguo Hu; Roderick T Bronson; Guo-Ping Shi; Jose A Halperin; Huseyin Aktas; Xuebin Qin
Complement regulator CD59 protects against angiotensin II-induced abdominal aortic aneurysms in mice.
Circulation 2010;121(11):1338-46.
2010: Haopeng Rui; Jennifer M Ritchie; Roderick T Bronson; John J Mekalanos; Yuanxing Zhang; Matthew K Waldor
Reactogenicity of live-attenuated Vibrio cholerae vaccines is dependent on flagellins.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4359-64.
2010: Junxia Min; Alexander Zaslavsky; Giuseppe Fedele; Sara K McLaughlin; Elizabeth E Reczek; Thomas De Raedt; Isil Guney; David E Strochlic; Laura E Macconaill; Rameen Beroukhim; Roderick T Bronson; Sandra Ryeom; William C Hahn; Massimo Loda; Karen Cichowski
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB.
Nature medicine 2010;16(3):286-94.
2010: Melanie Haas Kucherlapati; Kyeryoung Lee; Andrew A Nguyen; Alan B Clark; Harry Hou; Andrew Rosulek; Hua Li; Kan Yang; Kunhua Fan; Martin Lipkin; Roderick T Bronson; Linda Jelicks; Thomas A Kunkel; Raju Kucherlapati; Winfried Edelmann
An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.
Gastroenterology 2010;138(3):993-1002.e1.
2010: Thomas H Chase; Bonnie L Lyons; Roderick T Bronson; Oded Foreman; Leah Rae Donahue; Lisa M Burzenski; Bruce Gott; Priscilla Lane; Belinda Harris; Uta Ceglarek; Joachim Thiery; Henning Wittenburg; Jonathan N Thon; Joseph E Italiano; Kenneth R Johnson; Leonard D Shultz
The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.
Blood 2010;115(6):1267-76.
2010: David G Kirsch; Philip M Santiago; Emmanuelle di Tomaso; Julie M Sullivan; Wu-Shiun Hou; Talya Dayton; Laura B Jeffords; Pooja Sodha; Kim L Mercer; Rhianna Cohen; Osamu Takeuchi; Stanley J Korsmeyer; Roderick T Bronson; Carla F. Kim; Kevin M Haigis; Rakesh K Jain; Tyler Jacks
p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.
Science (New York, N.Y.) 2010;327(5965):593-6.
2010: Kenneth E Hung; Marco A Maricevich; Larissa Georgeon Richard; Wei Y Chen; Michael P Richardson; Alexandra Kunin; Roderick T Bronson; Umar Mahmood; Raju Kucherlapati
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(4):1565-70.
2010: Jennifer P Wang; Anna M Cerny; Damon R Asher; Evelyn A Kurt-Jones; Roderick T Bronson; Robert W Finberg
MDA5 and MAVS mediate type I interferon responses to coxsackie B virus.
Journal of virology 2010;84(1):254-60.
2009: Anthony C Faber; Danan Li; Youngchul Song; Mei-Chih Liang; Beow Y Yeap; Roderick T Bronson; Eugene Lifshits; Zhao Chen; Sauveur-Michel Maira; Carlos García-Echeverría; Kwok-Kin Wong; Jeffrey A Engelman
Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19503-8.
2009: Yoji Andrew MINAMISHIMA; Javid Moslehi; Robert F Padera; Roderick T Bronson; Ronglih Liao; William G Kaelin
A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.
Molecular and cellular biology 2009;29(21):5729-41.
2009: Sara R Abromson-Leeman; Roderick T Bronson; Martin E Dorf
Encephalitogenic T cells that stably express both T-bet and ROR gamma t consistently produce IFNgamma but have a spectrum of IL-17 profiles.
Journal of neuroimmunology 2009;215(1-2):10-24.
2009: Ru-Ju Chian; Jianhong Li; Ilknur Ay; Samuel A Celia; Brenda B Kashi; Eric Tamrazian; Jonathan C Matthews; Roderick T Bronson; Anthony Rossomando; R Blake Pepinsky; Paul S Fishman; Robert H Brown; Jonathan W Francis
IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.
Brain research 2009;1287():1-19.
2009: Andrew J Heilpern; Warren Wertheim; Jia He; George Perides; Roderick T Bronson; Linden T Hu
Matrix metalloproteinase 9 plays a key role in lyme arthritis but not in dissemination of Borrelia burgdorferi.
Infection and immunity 2009;77(7):2643-9.
2009: Adam Amsterdam; Kevin Lai; Anna Z Komisarczuk; Thomas S Becker; Roderick T Bronson; Nancy Hopkins; Jacqueline A Lees
Zebrafish Hagoromo mutants up-regulate fgf8 postembryonically and develop neuroblastoma.
Molecular cancer research : MCR 2009;7(6):841-50.
2009: Xue Han; Xiaofeng Qian; Jacob G Bernstein; Hui-Hui Zhou; Giovanni Talei Franzesi; Patrick Stern; Roderick T Bronson; Ann M Graybiel; Robert Desimone; Edward S Boyden
Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain.
Neuron 2009;62(2):191-8.
2009: Ying Feng; Matthew T Valley; Josef Lazar; Allison L Yang; Roderick T Bronson; Stuart Firestein; William A Coetzee; James L Manley
SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart.
Developmental cell 2009;16(4):528-38.
2009: Susan A Cook; Gayle B Collin; Roderick T Bronson; Jürgen K Naggert; Dong P Liu; Ellen C Akeson; Muriel T Davisson
A mouse model for Meckel syndrome type 3.
Journal of the American Society of Nephrology : JASN 2009;20(4):753-64.
2009: Toshiyuki Araki; Gordon Chan; Susan Newbigging; Lily Morikawa; Roderick T Bronson; Benjamin G Neel
Noonan syndrome cardiac defects are caused by PTPN11 acting in endocardium to enhance endocardial-mesenchymal transformation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(12):4736-41.
2009: Haihao Zhu; Jaime Acquaviva; Pranatartiharan Ramachandran; Abraham Boskovitz; Steve Woolfenden; Rolf Pfannl; Roderick T Bronson; John W Chen; Ralph Weissleder; David E Housman; Al Charest
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2712-6.
2009: Mari Kuraguchi; Nana Yaw Ohene-Baah; Dmitriy Sonkin; Roderick T Bronson; Raju Kucherlapati
Genetic mechanisms in Apc-mediated mammary tumorigenesis.
PLoS genetics 2009;5(2):e1000367.
2009: Lisiane Meira; Catherine A Moroski-Erkul; Stephanie L Green; Jennifer A Calvo; Roderick T Bronson; Dharini Shah; Leona D Samson
Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(3):888-93.
2009: Joanna Klapacz; Lisiane Meira; David G Luchetti; Jennifer A Calvo; Roderick T Bronson; Winfried Edelmann; Leona D Samson
O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):576-81.
2009: Samanthi A Perera; Danan Li; Takeshi Shimamura; Maria G Raso; Hongbin Ji; Liang Chen; Christa L Borgman; Sara Zaghlul; Kathleyn A Brandstetter; Shigeto Kubo; Masaya Takahashi; Lucian R Chirieac; Robert F Padera; Roderick T Bronson; Geoffrey I Shapiro; Heidi Greulich; Matthew Meyerson; Ulrich Guertler; Pilar Garin Chesa; Flavio Solca; Ignacio I Wistuba; Kwok-Kin Wong
HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):474-9.
2009: Roderick T Bronson
Pathologic phenotyping of mutant mice.
Methods in molecular biology (Clifton, N.J.) 2009;530():435-61.
2009: Kevin Lai; Adam Amsterdam; Sarah Farrington; Roderick T Bronson; Nancy Hopkins; Jacqueline A Lees
Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(1):76-85.
2009: Glen D Raffel; Gerald Chu; Jonathan L Jesneck; Dana E Cullen; Roderick T Bronson; Olivier A Bernard; D Gary Gilliland
Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen.
Molecular and cellular biology 2009;29(2):333-41.
2008: Paul S Danielian; L B Friesenhahn; A M Faust; J C West; Alicia M Caron; Roderick T Bronson; Jacqueline A Lees
E2f3a and E2f3b make overlapping but different contributions to total E2f3 activity.
Oncogene 2008;27(51):6561-70.
2008: Melanie Haas Kucherlapati; Kan Yang; Kunhua Fan; Mari Kuraguchi; Dmitriy Sonkin; Andrew Rosulek; Martin Lipkin; Roderick T Bronson; Bruce Aronow; Raju Kucherlapati
Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15493-8.
2008: Tan Ince; Jerrold M Ward; Victor E Valli; Dennis Sgroi; Alexander Nikitin; Massimo Loda; Stephen M Griffey; Christopher P Crum; James M Crawford; Roderick T Bronson; Robert Cardiff
Do-it-yourself (DIY) pathology.
Nature biotechnology 2008;26(9):978-9; discussion 979.
2008: John R Mills; Yoshitaka Hippo; Francis Robert; Samuel M H Chen; Abba Malina; Chen-Ju Lin; Ulrike Trojahn; Hans-Guido Wendel; Al Charest; Roderick T Bronson; Scott C Kogan; Robert Nadon; David E Housman; Scott W Lowe; Jerry Pelletier
mTORC1 promotes survival through translational control of Mcl-1.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10853-8.
2008: Joseph H McCarty; Marc Barry; Denise Crowley; Roderick T Bronson; Adam Lacy-Hulbert; Richard O Hynes
Genetic ablation of alphav integrins in epithelial cells of the eyelid skin and conjunctiva leads to squamous cell carcinoma.
The American journal of pathology 2008;172(6):1740-7.
2008: Samanthi A Perera; richard s maser; Huili Xia; Kate McNamara; Alexei Protopopov; Liang Chen; Aram F Hezel; Carla F. Kim; Roderick T Bronson; Diego H Castrillon; Lynda Chin; Nabeel Bardeesy; Ronald A DePinho; Kwok-Kin Wong
Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.
Carcinogenesis 2008;29(4):747-53.
2008: Yoji Andrew MINAMISHIMA; Javid Moslehi; Nabeel Bardeesy; Darragh Cullen; Roderick T Bronson; William G Kaelin
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.
Blood 2008;111(6):3236-44.
2008: Andrea Ventura; Amanda G Young; Monte M Winslow; Laura Lintault; Alexander Meissner; Stefan J Erkeland; Jamie Newman; Roderick T Bronson; Denise Crowley; James R Stone; Rudolf Jaenisch; Phillip A Sharp; Tyler Jacks
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters.
Cell 2008;132(5):875-86.
2008: Weiguo Hu; Sean P Ferris; Rodney K Tweten; Gongxiong Wu; Svetlana Radaeva; Bin Gao; Roderick T Bronson; Jose A Halperin; Xuebin Qin
Rapid conditional targeted ablation of cells expressing human CD59 in transgenic mice by intermedilysin.
Nature medicine 2008;14(1):98-103.
2008: Sunny Wong; Denise Crowley; Roderick T Bronson; Richard O Hynes
Analyses of the role of endogenous SPARC in mouse models of prostate and breast cancer.
Clinical & experimental metastasis 2008;25(2):109-18.
2007: Zhe Li; Cristina E Tognon; Frank J Godinho; Laura Yasaitis; Hanno Hock; Jason Herschkowitz; Chris L Lannon; Eunah Cho; Seong-Jin Kim; Roderick T Bronson; Charles M Perou; Poul H B Sorensen; Stuart H Orkin
ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex.
Cancer cell 2007;12(6):542-58.
2007: Sara R Abromson-Leeman; Daniel Ladell; Roderick T Bronson; Martin E Dorf
Heterogeneity of EAE mediated by multiple distinct T-effector subsets.
Journal of neuroimmunology 2007;192(1-2):3-12.
2007: David Lombard; Frederick W Alt; Hwei-Ling Cheng; Jakob Bunkenborg; Ryan S Streeper; Raul Mostoslavsky; Jennifer Kim; George D Yancopoulos; David M Valenzuela; Andrew Murphy; Yinhua Yang; Yaohui Chen; Matthew David Hirschey; Roderick T Bronson; Marcia Haigis; Leonard Guarente; Robert V Farese; Sherman Weissman; Eric Verdin; Bjoern Schwer
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Molecular and cellular biology 2007;27(24):8807-14.
2007: Craig Furman; Alisha L Sieminski; Adam V Kwiatkowski; Douglas A Rubinson; Eliza Vasile; Roderick T Bronson; Reinhard Fässler; Frank B Gertler
Ena/VASP is required for endothelial barrier function in vivo.
The Journal of cell biology 2007;179(4):761-75.
2007: Adam V Kwiatkowski; Douglas A Rubinson; Erik W Dent; J Edward van Veen; Jonathan D Leslie; Jiangyang Zhang; Leslie M Mebane; Ulrike Philippar; Elaine Pinheiro; Aurora A Burds; Roderick T Bronson; Susumu Mori; Reinhard Fässler; Frank B Gertler
Ena/VASP Is Required for neuritogenesis in the developing cortex.
Neuron 2007;56(3):441-55.
2007: Ted Valli; Stephen W Barthold; Jerrold E Ward; CORY BRAYTON; Alex Nikitin; Alexander D Borowsky; Roderick T Bronson; Robert Cardiff; John Sundberg; Tan Ince
Over 60% of NIH extramural funding involves animal-related research.
Veterinary pathology 2007;44(6):962-3, author reply 963-4.
2007: Stine Rasmussen; Yue Wang; Pia Kivisäkk; Roderick T Bronson; Morten Meyer; Jaime Imitola; Samia J Khoury
Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis.
Brain : a journal of neurology 2007;130(Pt 11):2816-29.
2007: Adam Lacy-Hulbert; Aileen M Smith; Hamid Tissire; Marc Barry; Denise Crowley; Roderick T Bronson; Jürgen Roes; John Savill; Richard O Hynes
Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15823-8.
2007: Yong Woo; S M Wright; S A Maas; T L Alley; L B Caddle; Sonya Kamdar; Jason P Affourtit; O Foreman; Ellen C Akeson; Daniel Shaffer; Roderick T Bronson; Herbert C Morse; D Roopenian; Kevin D Mills
The nonhomologous end joining factor Artemis suppresses multi-tissue tumor formation and prevents loss of heterozygosity.
Oncogene 2007;26(41):6010-20.
2007: Stephan Niemann; Hiroaki Kanki; Yasuyuki Fukui; Keizo Takao; MASAHIRO FUKAYA; Meri N Hynynen; Michael J Churchill; Jeremy M Shefner; Roderick T Bronson; Robert H Brown; Masahiko Watanabe; Tsuyoshi Miyakawa; Shigeyoshi Itohara; Yasunori Hayashi
Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes.
The European journal of neuroscience 2007;26(6):1407-20.
2007: David G Kirsch; Daniela M Dinulescu; John B Miller; Jan Grimm; Philip M Santiago; Nathan P Young; G Petur Nielsen; Bradley J Quade; Christopher J Chaber; Christian P Schultz; Osamu Takeuchi; Roderick T Bronson; Denise Crowley; Stanley J Korsmeyer; Sam S Yoon; Francis J Hornicek; Ralph Weissleder; Tyler Jacks
A spatially and temporally restricted mouse model of soft tissue sarcoma.
Nature medicine 2007;13(8):992-7.
2007: Ok S Shin; Aruna K Behera; Roderick T Bronson; Linden T Hu
Role of novel protein kinase C isoforms in Lyme arthritis.
Cellular microbiology 2007;9(8):1987-96.
2007: Sunny Wong; Herbert Haack; Joseph L Kissil; Marc Barry; Roderick T Bronson; Steven S Shen; Charles A Whittaker; Denise Crowley; Richard O Hynes
Protein 4.1B suppresses prostate cancer progression and metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12784-9.
2007: Kenneth R Johnson; Coleen C Marden; Patricia Ward-Bailey; Leona H Gagnon; Roderick T Bronson; Leah Rae Donahue
Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2.
Molecular endocrinology (Baltimore, Md.) 2007;21(7):1593-602.
2007: Hongbin Ji; Zhenxiong Wang; Samanthi A Perera; Danan Li; Mei-Chih Liang; Sara Zaghlul; Kate McNamara; Liang Chen; Mitchell S Albert; Yanping Sun; Ruqayyah Al-Hashem; Lucian R Chirieac; Robert F Padera; Roderick T Bronson; Roman K Thomas; Levi A Garraway; Pasi A Janne; Bruce E Johnson; Lynda Chin; Kwok-Kin Wong
Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
Cancer research 2007;67(10):4933-9.
2007: Paul S Danielian; Carla F Bender Kim; Alicia M Caron; Eliza Vasile; Roderick T Bronson; Jacqueline A Lees
E2f4 is required for normal development of the airway epithelium.
Developmental biology 2007;305(2):564-76.
2007: Kwok-Kin Wong; richard s maser; E Sahin; S T Bailey; Huili Xia; Hongbin Ji; Kate McNamara; M Naylor; Roderick T Bronson; S Ghosh; R Welsh; Ronald A DePinho
Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres.
Oncogene 2007;26(20):2815-21.
2007: Tanuja Chitnis; Jaime Imitola; Yue Wang; Wassim Elyaman; Prianka Chawla; Maia Sharuk; Khadir Raddassi; Roderick T Bronson; Samia J Khoury
Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration.
The American journal of pathology 2007;170(5):1695-712.
2007: Alice T Shaw; Alexander Meissner; James A Dowdle; Denise Crowley; Margaret Magendantz; Chensi Ouyang; Tiziana Parisi; Jayaraj Rajagopal; Leah J Blank; Roderick T Bronson; James R Stone; David A Tuveson; Rudolf Jaenisch; Tyler Jacks
Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis.
Genes & development 2007;21(6):694-707.
2007: Amitinder Kaur; Hannah B Sanford; Deirdre Garry; Sabine Lang; Sherry A Klumpp; Daisuke Watanabe; Roderick T Bronson; Jeffrey D Lifson; margherita rosati; George Pavlakis; Barbara K Felber; David M Knipe; Ronald C Desrosiers
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.
Virology 2007;357(2):199-214.
2006: Eun-Kyung Suh; Annie Yang; Arminja Kettenbach; Casimir Bamberger; Ala H Michaelis; Zhou Zhu; Julia A Elvin; Roderick T Bronson; Christopher P Crum; Frank McKeon
p63 protects the female germ line during meiotic arrest.
Nature 2006;444(7119):624-8.
2006: junhao mao; Keith L Ligon; Elena Y Rakhlin; Sarah P Thayer; Roderick T Bronson; David H Rowitch; Andrew P McMahon
A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway.
Cancer research 2006;66(20):10171-8.
2006: Cruz Jonathan; Dohoon Kim; Lily Y Moy; Matthew M Dobbin; Xiaoyan Sun; Roderick T Bronson; Li-Huei Tsai
p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid beta in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(41):10536-41.
2006: Mari Kuraguchi; Xiu-Ping Wang; Roderick T Bronson; Rebecca Rothenberg; Nana Yaw Ohene-Baah; Jennifer J Lund; Melanie Haas Kucherlapati; Richard L Maas; Raju Kucherlapati
Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.
PLoS genetics 2006;2(9):e146.
2006: Hongbin Ji; Danan Li; Liang Chen; Takeshi Shimamura; Susumu Kobayashi; Kate McNamara; Umar Mahmood; Albert Mitchell; Yangping Sun; Ruqayyah Al-Hashem; Lucian R Chirieac; Robert F Padera; Roderick T Bronson; William Kim; Pasi A Janne; Geoffrey I Shapiro; Daniel Tenen; Bruce E Johnson; Ralph Weissleder; Norman E Sharpless; Kwok-Kin Wong
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.
Cancer cell 2006;9(6):485-95.
2006: Hongbin Ji; Xiaojun Zhao; Yuki Yuza; Takeshi Shimamura; Danan Li; Alexei Protopopov; Boonim L Jung; Kate McNamara; Huili Xia; Karen A Glatt; Roman K Thomas; Hidefumi Sasaki; James W Horner; Michael J Eck; Albert Mitchell; Yangping Sun; Ruqayyah Al-Hashem; Roderick T Bronson; Sridhar K Rabindran; Carolyn Discafani; Elizabeth Maher; Geoffrey I Shapiro; Matthew Meyerson; Kwok-Kin Wong
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7817-22.
2006: Christine A Denny; Julie L Kasperzyk; Kristen N Gorham; Roderick T Bronson; Thomas N Seyfried
Influence of caloric restriction on motor behavior, longevity, and brain lipid composition in Sandhoff disease mice.
Journal of neuroscience research 2006;83(6):1028-38.
2006: Melanie Haas Kucherlapati; Andrew A Nguyen; Roderick T Bronson; Raju Kucherlapati
Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.
Cancer research 2006;66(7):3576-83.
2006: Hongbin Ji; A McGarry Houghton; T J Mariani; S Perera; Carla F. Kim; Robert F Padera; Giovanni Tonon; Kate McNamara; L A Marconcini; Aram F Hezel; N El-Bardeesy; Roderick T Bronson; D Sugarbaker; richard s maser; Steven D Shapiro; Kwok-Kin Wong
K-ras activation generates an inflammatory response in lung tumors.
Oncogene 2006;25(14):2105-12.
2006: Aruna K Behera; Ethan Hildebrand; Roderick T Bronson; George Perides; Satoshi Uematsu; Shizuo Akira; Linden T Hu
MyD88 deficiency results in tissue-specific changes in cytokine induction and inflammation in interleukin-18-independent mice infected with Borrelia burgdorferi.
Infection and immunity 2006;74(3):1462-70.
2006: Lina I Yoo; David W Liu; Sandrine Le Vu; Roderick T Bronson; Hong Wu; Junying Yuan
Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
Cancer research 2006;66(4):1929-39.
2006: Sandra L Gilbert; Li Zhang; Michele L Forster; Jeffrey R Anderson; Tamaki Iwase; Betty Soliven; Leah Rae Donahue; Hope O Sweet; Roderick T Bronson; Muriel T Davisson; Robert Wollmann; Bruce T Lahn
Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice.
Nature genetics 2006;38(2):245-50.
2006: Deborah Palliser; Dipanjan Chowdhury; Qing-Yin Wang; Sandra Lee; Roderick T Bronson; David M Knipe; Judy Lieberman
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection.
Nature 2006;439(7072):89-94.
2006: George Perides; Yuzheng Zhuge; Tina Lin; Monique F Stins; Roderick T Bronson; Julian K Wu
The fibrinolytic system facilitates tumor cell migration across the blood-brain barrier in experimental melanoma brain metastasis.
BMC cancer 2006;6():56.
2006: Qingcong Lin; Alan B Clark; Scott D McCulloch; Tao Yuan; Roderick T Bronson; Thomas A Kunkel; Raju Kucherlapati
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice.
Cancer research 2006;66(1):87-94.
2006: Karlyne M Reilly; Karl W Broman; Roderick T Bronson; Shirley Tsang; Dagan A Loisel; Emily S Christy; Zhonghe Sun; John Diehl; David J Munroe; Robert G Tuskan
An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.
Cancer research 2006;66(1):62-8.
2006: Chiaki Takahashi; Bernardo Contreras; Tsuyoshi Iwanaga; Yujiro Takegami; Anke Bakker; Roderick T Bronson; Makoto Noda; Massimo Loda; Jennifer L Hunt; Mark E Ewen
Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.
Nature genetics 2006;38(1):118-23.
2005: Daniela Taverna; Denise Crowley; Mary Connolly; Roderick T Bronson; Richard O Hynes
A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas.
Cancer research 2005;65(22):10324-9.
2005: Xuebin Qin; Martin Dobarro; Sylvia J Bedford; Sean Ferris; Patricia Miranda; Wenping Song; Roderick T Bronson; Pablo E Visconti; Jose A Halperin
Further characterization of reproductive abnormalities in mCd59b knockout mice: a potential new function of mCd59 in male reproduction.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6294-302.
2005: Sunny Wong; Herbert Haack; Denise Crowley; Marc Barry; Roderick T Bronson; Richard O Hynes
Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis.
Cancer research 2005;65(21):9789-98.
2005: Chunling Yi; Joseph H McCarty; Scott A Troutman; Matthew S Eckman; Roderick T Bronson; Joseph L Kissil
Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer.
Molecular and cellular biology 2005;25(22):10052-9.
2005: Takeshi Fujiwara; Madhavi Bandi; Masayuki Nitta; Elena V Ivanova; Roderick T Bronson; David Pellman
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells.
Nature 2005;437(7061):1043-7.
2005: Yu-Wen Zhang; Yanli Su; Nathan Lanning; Pamela Swiatek; Roderick T Bronson; Robert Sigler; Richard W Martin; George Vande Woude
Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(33):11740-5.
2005: Michelle R Marques; Jennifer S Horner; Rebecca A Ihrie; Roderick T Bronson; Laura D Attardi
Mice lacking the p53/p63 target gene Perp are resistant to papilloma development.
Cancer research 2005;65(15):6551-6.
2005: Carla F. Kim; Erica L. Jackson; Amber E Woolfenden; Sharon Lawrence; Imran Babar; Sinae Vogel; Denise Crowley; Roderick T Bronson; Tyler Jacks
Identification of bronchioalveolar stem cells in normal lung and lung cancer.
Cell 2005;121(6):823-35.
2005: Damon R Asher; Anna M Cerny; Sarah R Weiler; James W Horner; Marilyn L Keeler; Mychell A Neptune; Stephen N Jones; Roderick T Bronson; Ronald A DePinho; Robert W Finberg
Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development.
Genesis (New York, N.Y. : 2000) 2005;42(2):77-85.
2005: Florian P Limbourg; Kyosuke Takeshita; Freddy Radtke; Roderick T Bronson; Michael T Chin; James K Liao
Essential role of endothelial Notch1 in angiogenesis.
Circulation 2005;111(14):1826-32.
2005: Jan D Marshall; Roderick T Bronson; Gayle B Collin; Anne D Nordstrom; Pietro Maffei; Richard B Paisey; Catherine Carey; Seamus Macdermott; Isabelle Russell-Eggitt; Sarah E Shea; Judy Davis; Sebastian Beck; Gocha Shatirishvili; Cristina Maria Mihai; Maria Hoeltzenbein; Giovanni Battista Pozzan; Ian Hopkinson; Nicola Sicolo; Jürgen K Naggert; Patsy M Nishina
New Alström syndrome phenotypes based on the evaluation of 182 cases.
Archives of internal medicine 2005;165(6):675-83.
2005: Rebecca A Ihrie; Michelle R Marques; Bichchau T Nguyen; Jennifer S Horner; Cristian Papazoglu; Roderick T Bronson; Alea A Mills; Laura D Attardi
Perp is a p63-regulated gene essential for epithelial integrity.
Cell 2005;120(6):843-56.
2005: Joseph H McCarty; Adam Lacy-Hulbert; Al Charest; Roderick T Bronson; Denise Crowley; David E Housman; John Savill; Jürgen Roes; Richard O Hynes
Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death.
Development (Cambridge, England) 2005;132(1):165-76.
2004: Kenneth P Olive; David A Tuveson; Zachary C Ruhe; Bob Yin; Nicholas A Willis; Roderick T Bronson; Denise Crowley; Tyler Jacks
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome.
Cell 2004;119(6):847-60.
2004: Chiaki Takahashi; Bernardo Contreras; Roderick T Bronson; Massimo Loda; Mark E Ewen
Genetic interaction between Rb and K-ras in the control of differentiation and tumor suppression.
Molecular and cellular biology 2004;24(23):10406-15.
2004: Mengfatt Ho; Cristina M Post; Leah Rae Donahue; Hart G W Lidov; Roderick T Bronson; Holly Goolsby; simon simon watkins; Gregory A Cox; Robert H Brown
Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency.
Human molecular genetics 2004;13(18):1999-2010.
2004: Karlyne M Reilly; Robert G Tuskan; Emily Christy; Dagan A Loisel; Jeremy Ledger; Roderick T Bronson; C Dahlem Smith; Shirley Tsang; David J Munroe; Tyler Jacks
Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):13008-13.
2004: Katarzyna Kozar; Maria A Ciemerych; Vivienne Rebel; Hirokazu Shigematsu; Agnieszka Zagozdzon; Ewa Sicinska; Yan Geng; Qunyan Yu; Shoumo Bhattacharya; Roderick T Bronson; Koichi Akashi; Piotr Sicinski
Mouse development and cell proliferation in the absence of D-cyclins.
Cell 2004;118(4):477-91.
2004: Toshiyuki Araki; M Golam Mohi; Fraz A Ismat; Roderick T Bronson; Ifor Williams; Jeffery L Kutok; Wentian Yang; Lily I Pao; D Gary Gilliland; Jonathan A Epstein; Benjamin G Neel
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.
Nature medicine 2004;10(8):849-57.
2004: Jianxin Xie; Hao Zhu; Kevin Larade; Annie Ladoux; Ayden Seguritan; Michelle Chu; Susumu Ito; Roderick T Bronson; Edward H Leiter; Chen-Yu Zhang; Evan D Rosen; H Franklin Bunn
Absence of a reductase, NCB5OR, causes insulin-deficient diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10750-5.
2004: Elzbieta H Wloga; Vittoria Criniti; Lili Yamasaki; Roderick T Bronson
Lymphomagenesis and female-specific lethality in p53-deficient mice occur independently of E2f1.
Nature cell biology 2004;6(7):565-7; author reply 567-8.
2004: Anat Stemmer-Rachamimov; David N Louis; G Petur Nielsen; Cristina R Antonescu; Alexander D Borowsky; Roderick T Bronson; Dennis K Burns; Pascale Cervera; Margaret E McLaughlin; Guido Reifenberger; Michael C Schmale; Mia MacCollin; Richard C Chao; Karen Cichowski; Michel Kalamarides; Shanta M Messerli; Andrea I McClatchey; Michiko Niwa-Kawakita; Nancy Ratner; Karlyne M Reilly; Yuan Zhu; Marco Giovannini
Comparative pathology of nerve sheath tumors in mouse models and humans.
Cancer research 2004;64(10):3718-24.
2004: Adam Amsterdam; Kirsten C Sadler; Kevin Lai; Sarah Farrington; Roderick T Bronson; Jacqueline A Lees; Nancy Hopkins
Many ribosomal protein genes are cancer genes in zebrafish.
PLoS biology 2004;2(5):E139.
2004: Matthew A Holsti; Tanuja Chitnis; Ronald J Panzo; Roderick T Bronson; Hideo Yagita; Mohamed H Sayegh; Arthur O Tzianabos
Regulation of postsurgical fibrosis by the programmed death-1 inhibitory pathway.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5774-81.
2004: Sandra W Leung; Elzbieta H Wloga; Alejandro F Castro; Thao Nguyen; Roderick T Bronson; Lili Yamasaki
A dynamic switch in Rb+/- mediated neuroendocrine tumorigenesis.
Oncogene 2004;23(19):3296-307.
2004: David A Tuveson; Alice T Shaw; Nicholas A Willis; Daniel P Silver; Erica L. Jackson; Sandy Chang; Kim L Mercer; Rebecca Grochow; Hanno Hock; Denise Crowley; Sunil R Hingorani; Tal Zaks; Catrina King; Michael Jacobetz; Lifu Wang; Roderick T Bronson; Stuart H Orkin; Ronald A DePinho; Tyler Jacks
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.
Cancer cell 2004;5(4):375-87.
2004: Alexander Nikitin; Ana Alcaraz; Miriam R Anver; Roderick T Bronson; Robert Cardiff; Darlene Dixon; Armando E Fraire; Edward Gabrielson; William Gunning; Diana C Haines; Matthew H Kaufman; R Ilona Linnoila; Robert R Maronpot; Alan S Rabson; Robert L Reddick; Sabine Rehm; Nora Rozengurt; Hildegard M Schuller; Elena N Shmidt; William D Travis; Jerrold M Ward; Tyler Jacks
Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium.
Cancer research 2004;64(7):2307-16.
2004: Cristina López-Rodríguez; Christopher L Antos; John M Shelton; James A Richardson; Fangming Lin; Tatiana I Novobrantseva; Roderick T Bronson; Peter Igarashi; Anjana Rao; Eric N Olson
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2392-7.
2004: Chun Liu; Robert M Russell; Donald E Smith; Roderick T Bronson; Paul Milbury; Satoru Furukawa; Xiang Wang; Jeffrey B Blumberg
The effect of dietary glutathione and coenzyme Q10 on the prevention and treatment of inflammatory bowel disease in mice.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 2004;74(1):74-85.
2003: Leah Rae Donahue; Bo Chang; Subburaman Mohan; Naohisa Miyakoshi; Jon E Wergedal; David J Baylink; Norman L Hawes; Clifford J Rosen; Patricia Ward-Bailey; Qing Yin Zheng; Roderick T Bronson; Kenneth R Johnson; Muriel T Davisson
A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(9):1612-21.
2003: Ulrike Ziebold; Eunice Y Lee; Roderick T Bronson; Jacqueline A Lees
E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas.
Molecular and cellular biology 2003;23(18):6542-52.
2003: Kathleen G Banks; Kevin A Johnson; Charles P Lerner; Connie L Mahaffey; Roderick T Bronson; Elizabeth M Simpson
Retroposon compensatory mechanism hypothesis not supported: Zfa knockout mice are fertile.
Genomics 2003;82(3):254-60.
2003: Yan Geng; Qunyan Yu; Ewa Sicinska; Manjusri Das; Jürgen E Schneider; Shoumo Bhattacharya; William M Rideout; Roderick T Bronson; Humphrey Gardner; Piotr Sicinski
Cyclin E ablation in the mouse.
Cell 2003;114(4):431-43.
2003: Katrin Layer; Guosheng Lin; Alessio Nencioni; Wei Hu; Adam Schmucker; Andrey N Antov; Xiaoyu Li; Satoshi Takamatsu; Timothy Chevassut; Nancy A Dower; Stacey L Stang; David Beier; Janet Buhlmann; Roderick T Bronson; Keith B Elkon; James C Stone; Luk Van Parijs; Bing Lim
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.
Immunity 2003;19(2):243-55.
2003: Chiaki Takahashi; Roderick T Bronson; Merav Socolovsky; Bernardo Contreras; Kwang Youl Lee; Tyler Jacks; Makoto Noda; Raju Kucherlapati; Mark E Ewen
Rb and N-ras function together to control differentiation in the mouse.
Molecular and cellular biology 2003;23(15):5256-68.
2003: Carola A. Neumann; Diane S Krause; Christopher V Carman; Shampa Das; Devendra P Dubey; Jennifer L Abraham; Roderick T Bronson; Yuko Fujiwara; Stuart H Orkin; Richard A Van Etten
Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression.
Nature 2003;424(6948):561-5.
2003: Yuji Ikeno; Roderick T Bronson; Gene B Hubbard; Shuko Lee; Andrzej Bartke
Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences 2003;58(4):291-6.
2003: Matthew J Kohn; Roderick T Bronson; Ed Harlow; Nicholas J Dyson; Lili Yamasaki
Dp1 is required for extra-embryonic development.
Development (Cambridge, England) 2003;130(7):1295-305.
2003: David V Serreze; Melissa A Pierce; Cristina M Post; Harold D Chapman; Holly Savage; Roderick T Bronson; Paul B Rothman; Gregory A Cox
Paralytic autoimmune myositis develops in nonobese diabetic mice made Th1 cytokine-deficient by expression of an IFN-gamma receptor beta-chain transgene.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2742-9.
2003: David MacPherson; Julien Sage; Denise Crowley; Andreas Trumpp; Roderick T Bronson; Tyler Jacks
Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system.
Molecular and cellular biology 2003;23(3):1044-53.
2003: Sandra S Zinkel; Christy C Ong; David O Ferguson; Hiromi Iwasaki; Koichi Akashi; Roderick T Bronson; Jeffery L Kutok; Frederick W Alt; Stanley J Korsmeyer
Proapoptotic BID is required for myeloid homeostasis and tumor suppression.
Genes & development 2003;17(2):229-39.
2003: Kenneth R Johnson; Priscilla W Lane; Susan A Cook; Belinda S Harris; Patricia Ward-Bailey; Roderick T Bronson; Bonnie L Lyons; Leonard D Shultz; Muriel T Davisson
Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Genomics 2003;81(1):6-14.
2003: Hanno Hock; Melanie J Hamblen; Heather M Rooke; David Traver; Roderick T Bronson; Scott Cameron; Stuart H Orkin
Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation.
Immunity 2003;18(1):109-20.
2002: Maria A Ciemerych; Anna Marie Kenney; Ewa Sicinska; Ilona Kalaszczynska; Roderick T Bronson; David H Rowitch; Humphrey Gardner; Piotr Sicinski
Development of mice expressing a single D-type cyclin.
Genes & development 2002;16(24):3277-89.
2002: Jacqueline H Finger; Roderick T Bronson; Belinda Harris; Kenneth Johnson; Stefan Przyborski; Susan L Ackerman
The netrin 1 receptors Unc5h3 and Dcc are necessary at multiple choice points for the guidance of corticospinal tract axons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(23):10346-56.
2002: Talat H Malik; Dietrich von Stechow; Roderick T Bronson; Ramesh A Shivdasani
Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes.
Molecular and cellular biology 2002;22(24):8592-600.
2002: Vivienne Rebel; Andrew L Kung; Elizabeth A Tanner; Hong Yang; Roderick T Bronson; David M Livingston
Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):14789-94.
2002: Susan L Cotman; Vladimir Vrbanac; Lori-Anne Lebel; Richard L Lee; Kevin A Johnson; Leah Rae Donahue; Allison Teed; Kristen Antonellis; Roderick T Bronson; Terry J Lerner; Marcy E MacDonald
Cln3(Deltaex7/8) knock-in mice with the common JNCL mutation exhibit progressive neurologic disease that begins before birth.
Human molecular genetics 2002;11(22):2709-21.
2002: Geoffrey D Girnun; Wendy M Smith; Stavit Drori; pasha sarraf; Elisabetta Mueller; Charis Eng; Prashant R Nambiar; Daniel W Rosenberg; Roderick T Bronson; Winfried Edelmann; Raju Kucherlapati; Frank J Gonzalez; Bruce M Spiegelman
APC-dependent suppression of colon carcinogenesis by PPARgamma.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13771-6.
2002: Akira Inoue; Markus G Seidel; Wenshu Wu; Shintaro Kamizono; Adolfo Ferrando; Roderick T Bronson; Hiromi Iwasaki; Koichi Akashi; akira morimoto; Johann K Hitzler; Tamara I Pestina; Carl W Jackson; Ryuhei Tanaka; Miriam J Chong; Peter J McKinnon; Takeshi Inukai; Gerard C Grosveld; A Thomas Look
Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.
Cancer cell 2002;2(4):279-88.
2002: Jeffrey A Klein; Chantal M Longo-Guess; Marlies P Rossmann; Kevin Seburn; Ronald E Hurd; Wayne N Frankel; Roderick T Bronson; Susan L Ackerman
The harlequin mouse mutation downregulates apoptosis-inducing factor.
Nature 2002;419(6905):367-74.
2002: Ute Felbor; Benedikt Kessler; Walther Mothes; Hans H Goebel; Hidde L Ploegh; Roderick T Bronson; Bjorn R Olsen
Neuronal loss and brain atrophy in mice lacking cathepsins B and L.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):7883-8.
2002: Kelly A Young; Melissa L Berry; Connie L Mahaffey; Jennifer R Saionz; Norman L Hawes; Bo Chang; Qing Yin Zheng; Richard S Smith; Roderick T Bronson; Randy J Nelson; Elizabeth M Simpson
Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent.
Behavioural brain research 2002;132(2):145-58.
2002: Hong Yang; Bart Williams; Phillip W Hinds; T Shane Shih; Tyler Jacks; Roderick T Bronson; David M Livingston
Tumor suppression by a severely truncated species of retinoblastoma protein.
Molecular and cellular biology 2002;22(9):3103-10.
2002: Georg F Weber; Roderick T Bronson; John Ilagan; Harvey Cantor; Rudolf Schmits; Tak W Mak
Absence of the CD44 gene prevents sarcoma metastasis.
Cancer research 2002;62(8):2281-6.
2002: Jennifer King; Catherine Rogers; Tammi L Reza; Ulrike Ziebold; James R Stone; Michael H Picard; Alicia M Caron; Roderick T Bronson; Jacqueline A Lees
Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.
Molecular and cellular biology 2002;22(8):2663-72.
2002: Jian Kang; Roderick T Bronson; Yang Xu
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair.
The EMBO journal 2002;21(6):1447-55.
2002: Bruce J Herron; Weining Lu; Cherie Rao; Shanming Liu; Heiko Peters; Roderick T Bronson; Monica J Justice; J David McDonald; David Beier
Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.
Nature genetics 2002;30(2):185-9.
2002: Hanlin Gao; Rose-Mary N Boustany; Janice A Espinola; Susan L Cotman; Lakshmi Srinidhi; Kristen Auger Antonellis; Tammy Gillis; Xuebin Qin; Shumei Liu; Leah Rae Donahue; Roderick T Bronson; Jerry R Faust; Derek Stout; Jonathan L Haines; Terry J Lerner; Marcy E MacDonald
Mutations in a novel CLN6-encoded transmembrane protein cause variant neuronal ceroid lipofuscinosis in man and mouse.
American journal of human genetics 2002;70(2):324-35.
2001: Erica L. Jackson; Nicholas A Willis; Kim L Mercer; Roderick T Bronson; Denise Crowley; R Montoya; Tyler Jacks; David A Tuveson
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.
Genes & development 2001;15(24):3243-8.
2001: J Ko; S Humbert; Roderick T Bronson; S Takahashi; Ashok Kulkarni; En Li; Li-Huei Tsai
p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(17):6758-71.
2001: Roderick T Bronson; Leah Rae Donahue; R Samples; J H Kim; Jürgen K Naggert
Mice with mutations in the mahogany gene Atrn have cerebral spongiform changes.
Journal of neuropathology and experimental neurology 2001;60(7):724-30.
2001: L Johnson; Kim L Mercer; D Greenbaum; Roderick T Bronson; Denise Crowley; David A Tuveson; Tyler Jacks
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.
Nature 2001;410(6832):1111-6.
2001: Nancy J Wandersee; A N Roesch; NR Hamblen; J de Moes; Martin van der Valk; Roderick T Bronson; J A Gimm; Narla Mohandas; Peter Demant; Jane E Barker
Defective spectrin integrity and neonatal thrombosis in the first mouse model for severe hereditary elliptocytosis.
Blood 2001;97(2):543-50.
2001: Yan Geng; Qunyan Yu; Ewa Sicinska; Manjusri Das; Roderick T Bronson; Piotr Sicinski
Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):194-9.
2001: Susan A Cook; Ellen C Akeson; CJ Calvano; Kenneth R Johnson; J Mandell; Norman L Hawes; Roderick T Bronson; TH Roderick; Muriel T Davisson
Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene.
Cytogenetics and cell genetics 2001;93(1-2):77-82.
2001: C K Reeb-Whitaker; Beverly Paigen; W G Beamer; Roderick T Bronson; Gary Churchill; Isabelle Schweitzer; David D Myers
The impact of reduced frequency of cage changes on the health of mice housed in ventilated cages.
Laboratory animals 2001;35(1):58-73.
2000: Muriel T Davisson; Kenneth R Johnson; Roderick T Bronson; Patricia Ward-Bailey; Susan A Cook; Belinda S Harris; Leah Rae Donahue
Grey intense: a new mouse mutation affecting pigmentation.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(12):1139-41.
2000: Madeleine R Brouns; Stephen F Matheson; Kang-Quan Hu; Ivana Delalle; Verne S Caviness; J Silver; Roderick T Bronson; Jeffrey Settleman
The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development.
Development (Cambridge, England) 2000;127(22):4891-903.
2000: Patricia Ward-Bailey; B Wood; Kenneth R Johnson; Roderick T Bronson; Leah Rae Donahue; Muriel T Davisson
Neuromuscular ataxia: a new spontaneous mutation in the mouse.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(10):820-3.
2000: Karlyne M Reilly; Dagan A Loisel; Roderick T Bronson; Margaret E McLaughlin; Tyler Jacks
Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects.
Nature genetics 2000;26(1):109-13.
2000: P O Humbert; Catherine Rogers; S Ganiatsas; Rebecca L Landsberg; Jeffrey M Trimarchi; S Dandapani; C Brugnara; Susan E Erdman; Mark D Schrenzel; Roderick T Bronson; Jacqueline A Lees
E2F4 is essential for normal erythrocyte maturation and neonatal viability.
Molecular cell 2000;6(2):281-91.
2000: Boris Nikolic; S Lee; Roderick T Bronson; Michael J Grusby; Megan Sykes
Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets.
The Journal of clinical investigation 2000;105(9):1289-98.
2000: Andrew L Kung; Vivienne Rebel; Roderick T Bronson; L E Ch'ng; Colin A Sieff; David M Livingston; Tso-Pang Yao
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP.
Genes & development 2000;14(3):272-7.
2000: S Li; Q Wang; Abhijit Chakladar; Roderick T Bronson; Andre Bernards
Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1.
Molecular and cellular biology 2000;20(2):697-701.
1999: Karen Cichowski; T S Shih; E Schmitt; S Santiago; Karlyne M Reilly; Margaret E McLaughlin; Roderick T Bronson; Tyler Jacks
Mouse models of tumor development in neurofibromatosis type 1.
Science (New York, N.Y.) 1999;286(5447):2172-6.
1999: Ruth Lipman; Gerard Dallal; Roderick T Bronson
Effects of genotype and diet on age-related lesions in ad libitum fed and calorie-restricted F344, BN, and BNF3F1 rats.
The journals of gerontology. Series A, Biological sciences and medical sciences 1999;54(11):B478-91.
1999: Ruth Lipman; Gerard Dallal; Roderick T Bronson
Lesion biomarkers of aging in B6C3F1 hybrid mice.
The journals of gerontology. Series A, Biological sciences and medical sciences 1999;54(11):B466-77.
1999: Annie Yang; Ronen Schweitzer; D Sun; Mourad Kaghad; N Walker; Roderick T Bronson; Clifford J Tabin; A Sharpe; Daniel Caput; Christopher P Crum; Frank McKeon
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.
Nature 1999;398(6729):714-8.
1998: Yijie Gao; Yi E Sun; KM Frank; Pieter Dikkes; Y Fujiwara; KJ Seidl; JoAnn Sekiguchi; GA Rathbun; Wojciech Swat; J Wang; Roderick T Bronson; Barbara A Malynn; M Bryans; Chengming Zhu; Jayanta Chaudhuri; L Davidson; R Ferrini; Thomas D Stamato; Stuart H Orkin; Michael E Greenberg; Frederick W Alt
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis.
Cell 1998;95(7):891-902.
1998: Nancy J Wandersee; J C Lee; TM Kaysser; Roderick T Bronson; Jane E Barker
Hematopoietic cells from -spectrin-deficient mice are sufficient to induce thrombotic events in hematopoietically ablated recipients.
Blood 1998;92(12):4856-63.
1998: Ruth Lipman; D E Smith; Jeffrey B Blumberg; Roderick T Bronson
Effects of caloric restriction or augmentation in adult rats: longevity and lesion biomarkers of aging.
Aging (Milan, Italy) 1998;10(6):463-70.
1998: A J Koleske; A M Gifford; Martin L Scott; M Nee; Roderick T Bronson; Klaus Miczek; David Baltimore
Essential roles for the Abl and Arg tyrosine kinases in neurulation.
Neuron 1998;21(6):1259-72.
1998: Daniela Taverna; Marie-Hélène Disatnik; Helen Rayburn; Roderick T Bronson; Joy T Yang; Thomas A Rando; Richard O Hynes
Dystrophic muscle in mice chimeric for expression of alpha5 integrin.
The Journal of cell biology 1998;143(3):849-59.
1998: Qing Ma; D Jones; Paul R Borghesani; Rosalind A Segal; T Nagasawa; T Kishimoto; Roderick T Bronson; Timothy A Springer
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9448-53.
1998: Ruth Lipman; Roderick T Bronson; D Wu; D E Smith; R Prior; G Cao; Sung Nim Han; KR Martin; Simin Nikbin Meydani; Mohsen Meydani
Disease incidence and longevity are unaltered by dietary antioxidant supplementation initiated during middle age in C57BL/6 mice.
Mechanisms of ageing and development 1998;103(3):269-84.
1998: Kenneth R Johnson; Hope O Sweet; Leah Rae Donahue; Patricia Ward-Bailey; Roderick T Bronson; Muriel T Davisson
A new spontaneous mouse mutation of Hoxd13 with a polyalanine expansion and phenotype similar to human synpolydactyly.
Human molecular genetics 1998;7(6):1033-8.
1998: Roderick T Bronson; Leah Rae Donahue; Kenneth R Johnson; A Tanner; Priscilla W Lane; J R Faust
Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9.
American journal of medical genetics 1998;77(4):289-97.
1998: Priscilla W Lane; Roderick T Bronson; Susan A Cook; Patricia Ward-Bailey; Leah Rae Donahue; Muriel T Davisson
Juvenile bare: a new hair loss mutation on chromosome 7 of the mouse.
The Journal of heredity 1998;89(3):254-7.
1998: Tso-Pang Yao; S P Oh; M Fuchs; N D Zhou; L E Ch'ng; D Newsome; Roderick T Bronson; E Li; David M Livingston; R Eckner
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.
Cell 1998;93(3):361-72.
1998: James Brugarolas; Roderick T Bronson; Tyler Jacks
p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells.
The Journal of cell biology 1998;141(2):503-14.
1998: Andrea I McClatchey; Ichiko Saotome; Kim L Mercer; Denise Crowley; James Gusella; Roderick T Bronson; Tyler Jacks
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.
Genes & development 1998;12(8):1121-33.
1998: Daniela Taverna; MH Ullman-Culleré; Helen Rayburn; Roderick T Bronson; Richard O Hynes
A test of the role of alpha5 integrin/fibronectin interactions in tumorigenesis.
Cancer research 1998;58(4):848-53.
1997: TM Kaysser; Nancy J Wandersee; Roderick T Bronson; Jane E Barker
Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis.
Blood 1997;90(11):4610-9.
1997: Gregory A Cox; Cathleen M Lutz; Chao-Ling Yang; Daniel Biemesderfer; Roderick T Bronson; A Fu; Peter S Aronson; Jeffrey L Noebels; Wayne N Frankel
Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice.
Cell 1997;91(1):139-48.
1997: L Johnson; D Greenbaum; Karen Cichowski; Kim L Mercer; E Murphy; E Schmitt; Roderick T Bronson; H Umanoff; Winfried Edelmann; R Kucherlapati; Tyler Jacks
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
Genes & development 1997;11(19):2468-81.
1997: A Fazeli; Robert Steen; S L Dickinson; D Bautista; WF Dietrich; Roderick T Bronson; R S Bresalier; Eric S Lander; J Costa; Robert A. Weinberg
Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10199-204.
1997: Bruce H Horwitz; Martin L Scott; SR Cherry; Roderick T Bronson; David Baltimore
Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells.
Immunity 1997;6(6):765-72.
1997: Jie Shen; Roderick T Bronson; D F Chen; W Xia; Dennis J Selkoe; Susumu Tonegawa
Skeletal and CNS defects in Presenilin-1-deficient mice.
Cell 1997;89(4):629-39.
1997: A Fazeli; S L Dickinson; Michelle L Hermston; robert Tighe; Robert Steen; C G Small; ET Stoeckli; Kazuko Keino-Masu; Masayuki Masu; Helen Rayburn; J Simons; Roderick T Bronson; J I Gordon; Marc Tessier-Lavigne; Robert A. Weinberg
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene.
Nature 1997;386(6627):796-804.
1997: Belinda S Harris; T Franz; S Ullrich; S Cook; Roderick T Bronson; Muriel T Davisson
Forebrain overgrowth (fog): a new mutation in the mouse affecting neural tube development.
Teratology 1997;55(4):231-40.
1997: P M Janaswami; EH Birkenmeier; Susan A Cook; L B Rowe; Roderick T Bronson; Muriel T Davisson
Identification and genetic mapping of a new polycystic kidney disease on mouse chromosome 8.
Genomics 1997;40(1):101-7.
1997: Susan A Cook; Roderick T Bronson; Leah Rae Donahue; N Ben-Arie; Muriel T Davisson
Cerebellar deficient folia (cdf): a new mutation on mouse chromosome 6.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(2):108-12.
1996: Piotr Sicinski; J L Donaher; Y Geng; S B Parker; H Gardner; M Y Park; R L Robker; J S Richards; Lynda McGinnis; J D Biggers; J J Eppig; Roderick T Bronson; S J Elledge; Robert A. Weinberg
Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.
Nature 1996;384(6608):470-4.
1996: Leah Rae Donahue; Susan A Cook; Kenneth R Johnson; Roderick T Bronson; Muriel T Davisson
Megencephaly: a new mouse mutation on chromosome 6 that causes hypertrophy of the brain.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(12):871-6.
1996: Hope O Sweet; Roderick T Bronson; Kenneth R Johnson; Susan A Cook; Muriel T Davisson
Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(11):798-802.
1996: Y Xu; Terry Ashley; E E Brainerd; Roderick T Bronson; M Stephen Meyn; David Baltimore
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma.
Genes & development 1996;10(19):2411-22.
1996: M Nacht; A Strasser; Yvonne Chan; A W Harris; M Schlissel; Roderick T Bronson; Tyler Jacks
Mutations in the p53 and SCID genes cooperate in tumorigenesis.
Genes & development 1996;10(16):2055-66.
1996: David Cobrinik; M H Lee; G Hannon; G Mulligan; Roderick T Bronson; Nicholas J Dyson; Ed Harlow; D Beach; Robert A. Weinberg; Tyler Jacks
Shared role of the pRB-related p130 and p107 proteins in limb development.
Genes & development 1996;10(13):1633-44.
1996: M H Lee; Bart Williams; G Mulligan; S Mukai; Roderick T Bronson; Nicholas J Dyson; Ed Harlow; Tyler Jacks
Targeted disruption of p107: functional overlap between p107 and Rb.
Genes & development 1996;10(13):1621-32.
1996: Hope O Sweet; Roderick T Bronson; Leah Rae Donahue; Muriel T Davisson
Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse.
The Journal of heredity 1996;87(2):87-95.
1995: A A Beg; W C Sha; Roderick T Bronson; David Baltimore
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice.
Genes & development 1995;9(22):2736-46.
1995: Piotr Sicinski; J L Donaher; S B Parker; T Li; A Fazeli; H Gardner; Sandra Z Haslam; Roderick T Bronson; S J Elledge; Robert A. Weinberg
Cyclin D1 provides a link between development and oncogenesis in the retina and breast.
Cell 1995;82(4):621-30.
1995: A A Beg; W C Sha; Roderick T Bronson; S Ghosh; David Baltimore
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B.
Nature 1995;376(6536):167-70.
1995: V P Sah; Laura D Attardi; G J Mulligan; Bart Williams; Roderick T Bronson; Tyler Jacks
A subset of p53-deficient embryos exhibit exencephaly.
Nature genetics 1995;10(2):175-80.
1995: Susan A Cook; Kenneth R Johnson; Roderick T Bronson; Muriel T Davisson
Neuromuscular degeneration (nmd): a mutation on mouse chromosome 19 that causes motor neuron degeneration.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(3):187-91.
1994: Bart Williams; E M Schmitt; L Remington; Roderick T Bronson; D M Albert; Robert A. Weinberg; Tyler Jacks
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences.
The EMBO journal 1994;13(18):4251-9.
1994: Bart Williams; L Remington; D M Albert; S Mukai; Roderick T Bronson; Tyler Jacks
Cooperative tumorigenic effects of germline mutations in Rb and p53.
Nature genetics 1994;7(4):480-4.
1994: Tyler Jacks; T S Shih; E M Schmitt; Roderick T Bronson; A Bernards; Robert A. Weinberg
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1.
Nature genetics 1994;7(3):353-61.
1994: Glenn Dranoff; A D Crawford; Michel Sadelain; B Ream; Asif Rashid; Roderick T Bronson; G R Dickersin; C J Bachurski; E L Mark; J A Whitsett
Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis.
Science (New York, N.Y.) 1994;264(5159):713-6.
1994: Wesley G Beamer; Hope O Sweet; Roderick T Bronson; J G Shire; D N Orth; Muriel T Davisson
Adrenocortical dysplasia: a mouse model system for adrenocortical insufficiency.
The Journal of endocrinology 1994;141(1):33-43.
1994: Tyler Jacks; L Remington; Bart Williams; E M Schmitt; Shlomit Halachmi; Roderick T Bronson; Robert A. Weinberg
Tumor spectrum analysis in p53-mutant mice.
Current biology : CB 1994;4(1):1-7.
1992: Tyler Jacks; A Fazeli; E M Schmitt; Roderick T Bronson; M A Goodell; Robert A. Weinberg
Effects of an Rb mutation in the mouse.
Nature 1992;359(6393):295-300.
1991: Luanne L Peters; Connie S Birkenmeier; Roderick T Bronson; R A White; Samuel E Lux; E Otto; V Bennett; A Higgins; Jane E Barker
Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice.
The Journal of cell biology 1991;114(6):1233-41.
1991: V L Tybulewicz; C E Crawford; P K Jackson; Roderick T Bronson; R C Mulligan
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene.
Cell 1991;65(7):1153-63.