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Anamarija Zega

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Veronika Škedelj; Gregor Anderluh; Emilija Arsovska; Marija Bešter-Rogač; Julieanne Bostock; Ian Chopra; Stanislav Gobec; Vesna Hodnik; Martina Hrast; Ana Kroflič; Alex J O'Neill; Christopher Randall; Tihomir Tomašić; Anamarija Zega
6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase.
Nace Zidar; Roman Šink; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Stanislav Gobec; Andreja Kovač; Lucija Peterlin Mašič; Delphine Patin; Manica Müller Premru; Tihomir Tomašić; Anamarija Zega; Danijel Kikelj
New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation.
Tihomir Tomasić; Anamarija Zega; Nace Zidar; Manica Müller-Premru; Roman Sink; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Stanislav Gobec; Danijel Kikelj; Andreja Kovac; Lucija Peterlin Masic
Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).

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All Publications

2012: Veronika Škedelj; Gregor Anderluh; Emilija Arsovska; Marija Bešter-Rogač; Julieanne Bostock; Ian Chopra; Stanislav Gobec; Vesna Hodnik; Martina Hrast; Ana Kroflič; Alex J O'Neill; Christopher Randall; Tihomir Tomašić; Anamarija Zega
6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase.
PloS one 2012;7(8):e39922.
2011: Nace Zidar; Roman Šink; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Stanislav Gobec; Andreja Kovač; Lucija Peterlin Mašič; Delphine Patin; Manica Müller Premru; Tihomir Tomašić; Anamarija Zega; Danijel Kikelj
New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation.
European journal of medicinal chemistry 2011;46(11):5512-23.
2011: Tihomir Tomasić; Anamarija Zega; Nace Zidar; Manica Müller-Premru; Roman Sink; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Stanislav Gobec; Danijel Kikelj; Andreja Kovac; Lucija Peterlin Masic
Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).
Journal of medicinal chemistry 2011;54(13):4600-10.
2011: Izidor Sosič; Hélène Barreteau; Mihael Simčič; Roman Sink; Jozko Cesar; Anamarija Zega; Simona Golic Grdadolnik; Carlos A Contreras-Martel; Andréa Dessen; Ana Amoroso; Bernard Joris; Didier Blanot; Stanislav Gobec
Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid.
European journal of medicinal chemistry 2011;46(7):2880-94.
2011: Veronika Škedelj; Tihomir Tomašić; Lucija Peterlin Mašič; Anamarija Zega
ATP-binding site of bacterial enzymes as a target for antibacterial drug design.
Journal of medicinal chemistry 2011;54(4):915-29.
2010: Nace Zidar; Tihomir Tomasić; Roman Sink; Veronika Rupnik; Andreja Kovac; Samo Turk; Delphine Patin; Didier Blanot; Carlos A Contreras-Martel; Andréa Dessen; Manica Müller-Premru; Anamarija Zega; Stanislav Gobec; Lucija Peterlin-Masic; Danijel Kikelj
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.
Journal of medicinal chemistry 2010;53(18):6584-94.
2010: Tihomir Tomasić; Nace Zidar; Andreja Kovac; Samo Turk; Mihael Simcic; Didier Blanot; Manica Müller-Premru; Metka Filipic; Simona Golic Grdadolnik; Anamarija Zega; Marko Anderluh; Stanislav Gobec; Danijel Kikelj; Lucija Peterlin-Masic
5-Benzylidenethiazolidin-4-ones as multitarget inhibitors of bacterial Mur ligases.
ChemMedChem 2010;5(2):286-95.
2010: Roman Sink; Stanislav Gobec; Slavko Pečar; Anamarija Zega
False positives in the early stages of drug discovery.
Current medicinal chemistry 2010;17(34):4231-55.
2008: Roman Sink; Andreja Kovac; Tihomir Tomasić; Veronika Rupnik; Audrey Boniface; Julieanne Bostock; Ian Chopra; Didier Blanot; Lucija Peterlin Masic; Stanislav Gobec; Anamarija Zega
Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases.
ChemMedChem 2008;3(9):1362-70.
2008: Polona Smrdel; Marija Bogataj; Anamarija Zega; Odon Planinsek; Ales Mrhar
Shape optimization and characterization of polysaccharide beads prepared by ionotropic gelation.
Journal of microencapsulation 2008;25(2):90-105.
2008: Simona Strgulc Krajsek; Primoz Buh; Anamarija Zega; Samo Kreft
Identification of herbarium whole-leaf samples of Epilobium species by ATR-IR spectroscopy.
Chemistry & biodiversity 2008;5(2):310-7.
2006: Odon Planinsek; Daniela Planinsek; Anamarija Zega; Matej Breznik; Stane Srcic
Surface analysis of powder binary mixtures with ATR FTIR spectroscopy.
International journal of pharmaceutics 2006;319(1-2):13-9.
2006: Luka Peternel; Mateja Stempelj; Manica Cerne; Anamarija Zega; Ales Obreza; Marko Oblak; Gorazd Drevensek; Metka V Budihna; Lovro Stanovnik; Uros Urleb
Direct thrombin inhibitors built on the azaphenylalanine scaffold provoke degranulation of mast cells.
Thrombosis and haemostasis 2006;95(2):294-300.
2006: Lucija Peterlin-Masic; Jozko Cesar; Anamarija Zega
Metabolism-directed optimisation of antithrombotics: the prodrug principle.
Current pharmaceutical design 2006;12(1):73-91.
2005: Luka Peternel; Mojca Stegnar; Gorazd Drevensek; Metka V Budihna; Mojca Bozic; Anamarija Zega; Anton Stalc; Manica Cerne; Uros Urleb
Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models.
Thrombosis and haemostasis 2005;93(3):437-42.
2005: Anamarija Zega
Azapeptides as pharmacological agents.
Current medicinal chemistry 2005;12(5):589-97.
2004: Anamarija Zega; Gregor Mlinsek; Tom Solmajer; Alenka Trampus-Bakija; Mojca Stegnar; Uros Urleb
Thrombin inhibitors built on an azaphenylalanine scaffold.
Bioorganic & medicinal chemistry letters 2004;14(6):1563-7.
2001: Anamarija Zega; Gregor Mlinsek; P Sepic; S Golic Grdadolnik; Tom Solmajer; T B Tschopp; B Steiner; Danijel Kikelj; Uros Urleb
Design and structure-activity relationship of thrombin inhibitors with an azaphenylalanine scaffold: potency and selectivity enhancements via P2 optimization.
Bioorganic & medicinal chemistry 2001;9(10):2745-56.
2001: Anamarija Zega; Alenka Trampus-Bakija; M Fortuna; Mojca Stegnar; T B Tschopp; B Steiner; Uros Urleb
Novel thrombin inhibitors with azaphenylalanine scaffold.
Die Pharmazie 2001;56(9):683-5.