FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Eleftheria Zeggini

Research Profile

Genes & Molecular Sequences

Physiology

Disorders

Procedures

Concepts & Ideas

Geographic Areas

Great Britain

Living Beings

European Continental Ancestry Group

Chemicals & Drugs

Objects

Breakfast

Occupations

Genetics, Population

Co-author Network

Publications

TOP 3
Katherine S Elliott; Cecilia M Lindgren; John Loughlin; Andrew McCaskie; William E R Ollier; Kalliope Panoutsopoulou; Ashok Rai; Stuart Ralston; Mike R Reed; Lorraine Southam; Timothy D Spector; Ana M Valdes; Gillian A Wallis; Mark Wilkinson; Nigel Arden; Nadim Aslam; Fraser Birrell; Ian Carluke; Andrew Carr; Kay Chapman; Aaron Day-Williams; Panos Deloukas; Michael Doherty; Eleftheria Zeggini
Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data.
Ioanna Ntalla; Kalliope Panoutsopoulou; Lorraine Southam; Panagiota Vlachou; Nigel William Rayner; Eleftheria Zeggini; George V Dedoussis
Replication of Established Common Genetic Variants for Adult BMI and Childhood Obesity in Greek Adolescents: The TEENAGE Study.
Gavin Hudson; John Loughlin; Andrew McCaskie; William E R Ollier; Kalliope Panoutsopoulou; Stuart H Ralston; Nigel W Rayner; Mike R Reed; David Samuels; Lorraine Southam; Tim D Spector; Ana M Valdes; Gillian A Wallis; J Mark Wilkinson; Ian Wilson; Eleftheria Zeggini; Nigel Arden; Fraser Birrell; Ian Carluke; Andrew Carr; Kay Chapman; Patrick F Chinnery; Panos Deloukas; Michael Doherty
No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Eleftheria Zeggini (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Katherine S Elliott; Cecilia M Lindgren; John Loughlin; Andrew McCaskie; William E R Ollier; Kalliope Panoutsopoulou; Ashok Rai; Stuart Ralston; Mike R Reed; Lorraine Southam; Timothy D Spector; Ana M Valdes; Gillian A Wallis; Mark Wilkinson; Nigel Arden; Nadim Aslam; Fraser Birrell; Ian Carluke; Andrew Carr; Kay Chapman; Aaron Day-Williams; Panos Deloukas; Michael Doherty; Eleftheria Zeggini
Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data.
Annals of the rheumatic diseases 2013;72(6):935-41.
2013: Ioanna Ntalla; Kalliope Panoutsopoulou; Lorraine Southam; Panagiota Vlachou; Nigel William Rayner; Eleftheria Zeggini; George V Dedoussis
Replication of Established Common Genetic Variants for Adult BMI and Childhood Obesity in Greek Adolescents: The TEENAGE Study.
Annals of human genetics 2013;77(3):268-74.
2013: Gavin Hudson; John Loughlin; Andrew McCaskie; William E R Ollier; Kalliope Panoutsopoulou; Stuart H Ralston; Nigel W Rayner; Mike R Reed; David Samuels; Lorraine Southam; Tim D Spector; Ana M Valdes; Gillian A Wallis; J Mark Wilkinson; Ian Wilson; Eleftheria Zeggini; Nigel Arden; Fraser Birrell; Ian Carluke; Andrew Carr; Kay Chapman; Patrick F Chinnery; Panos Deloukas; Michael Doherty
No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls.
Annals of the rheumatic diseases 2013;72(1):136-9.
2012: Vesna Boraska; Lynn F Cherkas; Danai Christakopoulou; David A Collier; Oliver S P Davis; George V Dedoussis; Juliette Harris; Sietske G Helder; Jaakko Kaprio; Leila Karhunen; Anna Keski-Rahkonen; Isabel Krug; Ioanna Ntalla; Anu Raevuori; So-Youn Shin; Nicole Soranzo; Tim D Spector; Janet Treasure; Thomas Pei-Chi Liao; Eleftheria Zeggini
Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2012;159B(7):803-11.
2012: Gisela Orozco; Eleftheria Zeggini; John Ioannidis; Andrew Morris
Sex-specific differences in effect size estimates at established complex trait loci.
International journal of epidemiology 2012;41(5):1376-82.
2012: Jennifer Asimit; Vesna Boraska; Aaron Day-Williams; Igor Rudan; Lina Zgaga; Eleftheria Zeggini
An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity.
European journal of human genetics : EJHG 2012;20(6):709-12.
2012: Margarida C Lopes; Eleftheria Zeggini; Kalliope Panoutsopoulou
Do genome-wide association scans have potential for translation?
Clinical chemistry and laboratory medicine : CCLM / FESCC 2012;50(2):255-60.
2012: Jennifer L Asimit; Eleftheria Zeggini
Imputation of rare variants in next-generation association studies.
Human heredity 2012;74(3-4):196-204.
2012: Ioanna Tachmazidou; Andrew Morris; Eleftheria Zeggini
Rare Variant Association Testing for Next-Generation Sequencing Data via Hierarchical Clustering.
Human heredity 2012;74(3-4):165-71.
2012: Marie-Claude Babron; Marie de Tayrac; Douglas N Rutledge; Eleftheria Zeggini; Emmanuelle Génin
Rare and low frequency variant stratification in the UK population: description and impact on association tests.
PloS one 2012;7(10):e46519.
2012: Jennifer L Asimit; Aaron G Day-Williams; Andrew P Morris; Eleftheria Zeggini
ARIEL and AMELIA: testing for an accumulation of rare variants using next-generation sequencing data.
Human heredity 2012;73(2):84-94.
2012: Margarida C Lopes; Graham R S Ritchie; Jennifer Asimit; Fiona Cunningham; Sally L John; Chris Joyce; Eleftheria Zeggini
A combined functional annotation score for non-synonymous variants.
Human heredity 2012;73(1):47-51.
2011: Kay Chapman; Teresa Ferreira; Andrew Morris; Jennifer Asimit; Eleftheria Zeggini
Defining the power limits of genome-wide association scan meta-analyses.
Genetic epidemiology 2011;35(8):781-9.
2011: Stephen Eyre; Xiayi Ke; Rachel Lawrence; John Bowes; K Panoutsopoulou; Anne Barton; Wendy Thomson; Jane Worthington; Eleftheria Zeggini
Examining the overlap between genome-wide rare variant association signals and linkage peaks in rheumatoid arthritis.
Arthritis and rheumatism 2011;63(6):1522-6.
2011: Lorraine Southam; Timothy D Spector; Ana M Valdes; Gillian A Wallis; J Mark Wilkinson; Nigel Arden; Andrew Carr; Kay Chapman; Panos Deloukas; Michael Doherty; Caroline Durrant; Teresa Ferreira; John Loughlin; Jonathan Marchini; Andrew McCaskie; William E R Ollier; Kalliope Panoutsopoulou; Stuart Ralston; N William Rayner; Eleftheria Zeggini
The effect of genome-wide association scan quality control on imputation outcome for common variants.
European journal of human genetics : EJHG 2011;19(5):610-4.
2011: Aaron G Day-Williams; Eleftheria Zeggini
The effect of next-generation sequencing technology on complex trait research.
European journal of clinical investigation 2011;41(5):561-7.
2011: Eleftheria Zeggini
Next-generation association studies for complex traits.
Nature genetics 2011;43(4):287-8.
2011: Aaron G Day-Williams; Eleanor Drury; Sarah Edkins; Kirsten McLay; Aarno Palotie; Alison J Coffey; Eleftheria Zeggini
An evaluation of different target enrichment methods in pooled sequencing designs for complex disease association studies.
PloS one 2011;6(11):e26279.
2011: Carl A Anderson; Nicole Soranzo; Eleftheria Zeggini; Jeffrey C Barrett
Synthetic associations are unlikely to account for many common disease genome-wide association signals.
PLoS biology 2011;9(1):e1000580.
2011: Jordana Tzenova Bell; Nicholas J Timpson; N William Rayner; Eleftheria Zeggini; Timothy M Frayling; Andrew T Hattersley; Andrew P Morris; Mark I McCarthy
Genome-wide association scan allowing for epistasis in type 2 diabetes.
Annals of human genetics 2011;75(1):10-9.
2011: Eleftheria Zeggini; J L Asimit
An evaluation of power to detect low-frequency variant associations using allele-matching tests that account for uncertainty.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2011;():100-5.
2010: John Bowes; Robert Lawrence; Stephen Eyre; Kalliope Panoutsopoulou; Gisela Orozco; Katherine S Elliott; Xiayi Ke; Andrew P Morris; Wendy Thomson; Jane Worthington; Anne Barton; Eleftheria Zeggini
Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.
Human genetics 2010;128(6):627-33.
2010: Gisela Orozco; Jeffrey C Barrett; Eleftheria Zeggini
Synthetic associations in the context of genome-wide association scan signals.
Human molecular genetics 2010;19(R2):R137-44.
2010: Andrew P Morris; Cecilia M Lindgren; Eleftheria Zeggini; Nicholas J Timpson; Timothy M Frayling; Andrew T Hattersley; Mark I McCarthy
A powerful approach to sub-phenotype analysis in population-based genetic association studies.
Genetic epidemiology 2010;34(4):335-43.
2010: Andrew P Morris; Eleftheria Zeggini
An evaluation of statistical approaches to rare variant analysis in genetic association studies.
Genetic epidemiology 2010;34(2):188-93.
2010: Jennifer Asimit; Eleftheria Zeggini
Rare variant association analysis methods for complex traits.
Annual review of genetics 2010;44():293-308.
2010: Robert Lawrence; Aaron G Day-Williams; Katherine S Elliott; Andrew P Morris; Eleftheria Zeggini
CCRaVAT and QuTie-enabling analysis of rare variants in large-scale case control and quantitative trait association studies.
BMC bioinformatics 2010;11():527.
2010: Vesna Boraska; Nigel W Rayner; Christopher J Groves; Timothy M Frayling; Mahamadou DIAKITE; Kirk Rockett; Dominic P Kwiatkowski; Aaron G Day-Williams; Mark I McCarthy; Eleftheria Zeggini
Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes.
BMC medical genetics 2010;11():69.
2010: D Schleinitz; Anke Tönjes; Yvonne Böttcher; K Dietrich; Beate Enigk; M Koriath; Gerhard Scholz; Matthias Blüher; Eleftheria Zeggini; M I McCarthy; Peter Kovacs; Michael Stumvoll
Lack of significant effects of the type 2 diabetes susceptibility loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on diabetes and quantitative metabolic traits.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2010;42(1):14-22.
2010: Anke Tönjes; Eleftheria Zeggini; Peter Kovacs; Yvonne Böttcher; Dorit Schleinitz; Kerstin Dietrich; Andrew P Morris; Beate Enigk; Nigel W Rayner; Moritz Koriath; Markus Eszlinger; Anu Kemppinen; Inga Prokopenko; Katrin Hoffmann; Daniel Teupser; Joachim Thiery; Knut Krohn; Mark I McCarthy; Michael Stumvoll
Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.
European journal of human genetics : EJHG 2010;18(1):104-10.
2009: Ulf Strömberg; Jonas Björk; Paolo Vineis; Karin Broberg; Eleftheria Zeggini
Ranking of genome-wide association scan signals by different measures.
International journal of epidemiology 2009;38(5):1364-73.
2009: Kalliope Panoutsopoulou; Eleftheria Zeggini
Finding common susceptibility variants for complex disease: past, present and future.
Briefings in functional genomics & proteomics 2009;8(5):345-52.
2009: Lorraine Southam; N Soranzo; S B Montgomery; Timothy M Frayling; Mark I McCarthy; I Barroso; Eleftheria Zeggini
Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
Diabetologia 2009;52(9):1846-51.
2009: John R B Perry; Mark I McCarthy; Andrew T Hattersley; Eleftheria Zeggini; Michael Weedon; Timothy M Frayling
Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach.
Diabetes 2009;58(6):1463-7.
2009: Rachel M Freathy; Amanda J Bennett; Susan M Ring; Beverley Shields; Christopher J Groves; Nicholas J Timpson; Michael Weedon; Eleftheria Zeggini; Cecilia M Lindgren; Hana Lango; John R B Perry; Anneli Pouta; Aimo Ruokonen; Elina Hyppönen; Chris Power; Paul Elliott; David P Strachan; Marjo-Riitta Järvelin; George Davey Smith; Mark I McCarthy; Timothy M Frayling; Andrew T Hattersley
Type 2 diabetes risk alleles are associated with reduced size at birth.
Diabetes 2009;58(6):1428-33.
2009: Mark I McCarthy; Eleftheria Zeggini
Genome-wide association studies in type 2 diabetes.
Current diabetes reports 2009;9(2):164-71.
2009: Vesna Boraska; Eleftheria Zeggini; Christopher J Groves; Nigel W Rayner; Veselin Skrabić; Mahamadou DIAKITE; Kirk Rockett; Dominic Kwiatkowski; Mark I McCarthy; Tatijana Zemunik
Family-based analysis of tumor necrosis factor and lymphotoxin-alpha tag polymorphisms with type 1 diabetes in the population of South Croatia.
Human immunology 2009;70(3):195-9.
2009: Eleftheria Zeggini; John Ioannidis
Meta-analysis in genome-wide association studies.
Pharmacogenomics 2009;10(2):191-201.
2009: Nicholas J Timpson; Cecilia M Lindgren; Michael Weedon; Joshua Randall; Willem H Ouwehand; David P Strachan; N William Rayner; Mark Walker; Graham A Hitman; Alex S F Doney; Colin N A Palmer; Andrew D Morris; Andrew T Hattersley; Eleftheria Zeggini; Timothy M Frayling; Mark I McCarthy
Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
Diabetes 2009;58(2):505-10.
2009: Jennifer Asimit; Eleftheria Zeggini
Testing for rare variant associations in complex diseases.
Genome medicine 2009;1(11):24.
2009: Andrew P Morris; Eleftheria Zeggini; Cecilia M Lindgren
Identification of novel putative rheumatoid arthritis susceptibility genes via analysis of rare variants.
BMC proceedings 2009;3 Suppl 7():S131.
2009: Robert Lawrence; Aaron G Day-Williams; Richard Mott; John Broxholme; Lon R Cardon; Eleftheria Zeggini
GLIDERS--a web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs.
BMC bioinformatics 2009;10():367.
2008: Inês Barroso; Jian'an Luan; Eleanor Wheeler; Pamela Whittaker; Jon Wasson; Eleftheria Zeggini; Michael N Weedon; Sarah Hunt; Ranganath Venkatesh; Timothy M Frayling; Marcos Delgado; Rosalind J Neuman; Jinghua Zhao; Richard Sherva; Benjamin Glaser; Mark Walker; Graham A Hitman; Mark I McCarthy; Andrew T Hattersley; M Alan Permutt; Nicholas J Wareham; Panos Deloukas
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.
Diabetes 2008;57(11):3161-5.
2008: Hana Lango; Colin N A Palmer; Andrew D Morris; Eleftheria Zeggini; Andrew T Hattersley; Mark I McCarthy; Timothy M Frayling; Michael Weedon
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.
Diabetes 2008;57(11):3129-35.
2008: Michael Weedon; Nicholas J Timpson; Debbie A Lawlor; Anneli Pouta; Yoav Ben-Shlomo; Aimo Ruokonen; Shah Ebrahim; Beverley Shields; Eleftheria Zeggini; Michael N Weedon; Cecilia M Lindgren; Hana Lango; David Melzer; Luigi Ferrucci; Giuseppe Paolisso; Matthew J Neville; Fredrik Karpe; Colin N A Palmer; Andrew D Morris; Paul Elliott; Marjo-Riitta Jarvelin; George Davey Smith; Mark I McCarthy; Andrew T Hattersley; Timothy M Frayling
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.
Diabetes 2008;57(5):1419-26.
2008: Steven Wiltshire; Andrew P Morris; Eleftheria Zeggini
Examining the statistical properties of fine-scale mapping in large-scale association studies.
Genetic epidemiology 2008;32(3):204-14.
2008: Vesna Boraska; Veselin Skrabić; Eleftheria Zeggini; Christopher James Groves; Maja Buljubasić; Marijana Peruzović; Tatijana Zemunik
Family-based analysis of vitamin D receptor gene polymorphisms and type 1 diabetes in the population of South Croatia.
Journal of human genetics 2008;53(3):210-4.
2007: Mark I McCarthy; Eleftheria Zeggini
Genome-wide association scans for Type 2 diabetes: new insights into biology and therapy.
Trends in pharmacological sciences 2007;28(12):598-601.
2007: Laura Pascoe; Andrea Tura; Sheila K Patel; Ibrahim M Ibrahim; Ele Ferrannini; Eleftheria Zeggini; Michael Weedon; Andrea Mari; Andrew T Hattersley; Mark I McCarthy; Timothy M Frayling; Mark Walker
Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.
Diabetes 2007;56(12):3101-4.
2007: Eleftheria Zeggini
A new era for Type 2 diabetes genetics.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(11):1181-6.
2007: Thomas M Barber; Amanda J Bennett; Christopher J Groves; Ulla Sovio; Aimo Ruokonen; Hannu Martikainen; Anneli Pouta; Anna-Liisa Hartikainen; Paul Elliott; J A H Wass; Marjo-Riitta Järvelin; Eleftheria Zeggini; Stephen Franks; Mark I McCarthy
Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS.
Diabetologia 2007;50(11):2318-22.
2007: Eleftheria Zeggini; Michael N Weedon; Cecilia M Lindgren; Timothy M Frayling; Katherine S Elliott; Hana Lango; Nicholas J Timpson; John R B Perry; Nigel W Rayner; Michael Weedon; Jeffrey C Barrett; Beverley Shields; Andrew P Morris; Sian Ellard; Christopher J Groves; Lorna W Harries; Jonathan Marchini; Katharine R Owen; Beatrice Knight; Lon R Cardon; Mark Walker; Graham A Hitman; Andrew D Morris; Alex S F Doney; Mark I McCarthy; Andrew T Hattersley
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
Science (New York, N.Y.) 2007;316(5829):1336-41.
2007: Thomas M Barber; Amanda J Bennett; Anna L Gloyn; Christopher J Groves; Ulla Sovio; Aimo Ruokonen; Hannu Martikainen; Anneli Pouta; Saara Taponen; Michael Weedon; Anna-Liisa Hartikainen; J A H Wass; Marjo-Riitta Järvelin; Eleftheria Zeggini; Stephen Franks; Mark I McCarthy
Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.
European journal of human genetics : EJHG 2007;15(6):679-84.
2007: Katharine R Owen; Christopher J Groves; Robert L Hanson; William C Knowler; Alan R Shuldiner; Steven C Elbein; Braxton D Mitchell; philippe froguel; Maggie C Y Ng; Juliana C Chan; Weiping Jia; Panos Deloukas; Graham A Hitman; Mark Walker; Timothy M Frayling; Andrew T Hattersley; Eleftheria Zeggini; Mark I McCarthy
Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.
Diabetes 2007;56(3):879-83.
2007: Winston S Chu; Swapan Kumar Das; Hua Wang; Juliana C Chan; Panos Deloukas; philippe froguel; Leslie J Baier; Weiping Jia; Mark I McCarthy; Maggie C Y Ng; Coleen M Damcott; Alan R Shuldiner; Eleftheria Zeggini; Steven C Elbein
Activating transcription factor 6 (ATF6) sequence polymorphisms in type 2 diabetes and pre-diabetic traits.
Diabetes 2007;56(3):856-62.
2007: Eleftheria Zeggini; Mark I McCarthy
Identifying susceptibility variants for type 2 diabetes.
Methods in molecular biology (Clifton, N.J.) 2007;376():235-50.
2007: Minal Desai; Eleftheria Zeggini; Virginia Horton; Katharine R Owen; Andrew T Hattersley; Jonathan C Levy; Mark Walker; K M Gillespie; Polly J Bingley; Graham A Hitman; Rury R Holman; Mark I McCarthy; Anne Clark
An association analysis of the HLA gene region in latent autoimmune diabetes in adults.
Diabetologia 2007;50(1):68-73.
2007: Eleftheria Zeggini; Mark I McCarthy
TCF7L2: the biggest story in diabetes genetics since HLA?
Diabetologia 2007;50(1):1-4.
2006: R Calle; Mark I McCarthy; P Banerjee; Eleftheria Zeggini; Carole A Cull; Kerensa I Thorne; Steven Wiltshire; S Terra; D Meyer; J Richmond; J Mancuso; Patrice M Milos; D Fryburg; Rury R Holman
Paraoxonase 2 (PON2) polymorphisms and development of renal dysfunction in type 2 diabetes: UKPDS 76.
Diabetologia 2006;49(12):2892-9.
2006: Michael Weedon; Mark I McCarthy; Graham A Hitman; Mark Walker; Christopher J Groves; Eleftheria Zeggini; Nigel W Rayner; Beverley Shields; Katharine R Owen; Andrew T Hattersley; Timothy M Frayling
Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.
PLoS medicine 2006;3(10):e374.
2006: Christopher J Groves; Eleftheria Zeggini; Jayne A L Minton; Timothy M Frayling; Michael Weedon; Nigel W Rayner; Graham A Hitman; Mark Walker; Steven Wiltshire; Andrew T Hattersley; Mark I McCarthy
Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.
Diabetes 2006;55(9):2640-4.
2006: Swapan Kumar Das; Winston S Chu; Terri C Hale; Xiaoqin Wang; Rebekah L Craig; Hua Wang; Alan R Shuldiner; philippe froguel; Panos Deloukas; Mark I McCarthy; Eleftheria Zeggini; Sandra J Hasstedt; Steven C Elbein
Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes.
Diabetes 2006;55(9):2631-9.
2006: Eleftheria Zeggini; Coleen M Damcott; Robert L Hanson; Mohammad A Karim; Nigel W Rayner; Christopher J Groves; Leslie J Baier; Terri C Hale; Andrew T Hattersley; Graham A Hitman; Sarah E Hunt; William C Knowler; Braxton D Mitchell; Maggie C Y Ng; Jeffrey R O'Connell; Toni I Pollin; Martine Vaxillaire; Mark Walker; Xiaoqin Wang; Pamela Whittaker; Kun-san Xiang; Xiang Kunsun; Weiping Jia; Juliana C N Chan; philippe froguel; Panos Deloukas; Alan R Shuldiner; Steven C Elbein; Mark I McCarthy
Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.
Diabetes 2006;55(9):2541-8.
2006: Eleftheria Zeggini; J Packham; Rachelle Donn; Paul Wordsworth; A Hall; Wendy Thomson
Association of HLA-DRB1*13 with susceptibility to uveitis in juvenile idiopathic arthritis in two independent data sets.
Rheumatology (Oxford, England) 2006;45(8):972-4.
2006: Minal Desai; Eleftheria Zeggini; Virginia Horton; Katharine R Owen; Andrew T Hattersley; Jonathan C Levy; Graham A Hitman; Mark Walker; Rury R Holman; Mark I McCarthy; Anne Clark
The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults.
Diabetes 2006;55(6):1890-4.
2006: Christopher J Groves; Eleftheria Zeggini; Mark Walker; Graham A Hitman; Jonathan C Levy; Stephen O'Rahilly; Andrew T Hattersley; Mark I McCarthy; Steven Wiltshire
Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.
Diabetes 2006;55(6):1884-9.
2006: Mark I McCarthy; Eleftheria Zeggini
Genetics of type 2 diabetes.
Current diabetes reports 2006;6(2):147-54.
2005: Eleftheria Zeggini; J R C Parkinson; Stephanie Halford; Katharine R Owen; Mark Walker; Graham A Hitman; Jonathan C Levy; Mike J Sampson; Timothy M Frayling; Andrew T Hattersley; Mark I McCarthy
Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(12):1696-700.
2005: Eleftheria Zeggini; William Rayner; Andrew P Morris; Andrew T Hattersley; Mark Walker; Graham A Hitman; Panos Deloukas; Lon R Cardon; Mark I McCarthy
An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets.
Nature genetics 2005;37(12):1320-2.
2005: L J Gibbons; Wendy Thomson; Eleftheria Zeggini; Jane Worthington; Anne Barton; Stephen Eyre; Rachelle Donn; Anne Hinks
The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis.
Rheumatology (Oxford, England) 2005;44(11):1390-3.
2005: Eleftheria Zeggini; Christopher J Groves; J R C Parkinson; Stephanie Halford; Katharine R Owen; Timothy M Frayling; Mark Walker; Graham A Hitman; Jonathan C Levy; Stephen O'Rahilly; Andrew T Hattersley; Mark I McCarthy
Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes.
Diabetologia 2005;48(10):2013-7.
2005: Brenda L Powell; Lema Haddad; Amanda Bennett; Neda Gharani; Ulla Sovio; Christopher J Groves; Karen Rush; Micaela J Goh; Gerard S Conway; Aimo Ruokonen; Hannu Martikainen; Anneli Pouta; Saara Taponen; Anna-Liisa Hartikainen; Stephanie Halford; Eleftheria Zeggini; Marjo-Riitta Järvelin; Stephen Franks; Mark I McCarthy
Analysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits.
The Journal of clinical endocrinology and metabolism 2005;90(5):2988-93.
2005: Rebecca Lamb; Eleftheria Zeggini; Wendy Thomson; Rachelle Donn
Toll-like receptor 4 gene polymorphisms and susceptibility to juvenile idiopathic arthritis.
Annals of the rheumatic diseases 2005;64(5):767-9.
2005: Mahsa M Amoli; Fiona Salway; Eleftheria Zeggini; W E R Ollier; Miguel A Gonzalez-Gay
MCP-1 gene haplotype association in biopsy proven giant cell arteritis.
The Journal of rheumatology 2005;32(3):507-10.
2005: Neil Shephard; Sally John; Lon Cardon; Mark I McCarthy; Eleftheria Zeggini
Will the real disease gene please stand up?
BMC genetics 2005;6 Suppl 1():S66.
2005: Eleftheria Zeggini; Anne Barton; Stephen Eyre; Daniel Ward; W E R Ollier; Jane Worthington; Sally John
Characterisation of the genomic architecture of human chromosome 17q and evaluation of different methods for haplotype block definition.
BMC genetics 2005;6():21.
2004: C F Liew; Christopher J Groves; Steven Wiltshire; Eleftheria Zeggini; Timothy M Frayling; Katharine R Owen; Mark Walker; Graham A Hitman; Jonathan C Levy; Stephen O'Rahilly; Andrew T Hattersley; Desmond G Johnston; Mark I McCarthy
Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.
Diabetologia 2004;47(12):2168-75.
2004: William Brintnell; Eleftheria Zeggini; Anne Barton; Wendy Thomson; Stephen Eyre; Anne Hinks; Alan J Silman; Jane Worthington
Evidence for a novel rheumatoid arthritis susceptibility locus on chromosome 6p.
Arthritis and rheumatism 2004;50(12):3823-30.
2004: Mahsa M Amoli; Miguel A Gonzalez-Gay; Eleftheria Zeggini; Fiona Salway; Carlos Garcia-Porrua; W E R Ollier
Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis.
The Journal of rheumatology 2004;31(12):2413-7.
2004: Eleftheria Zeggini; James Parkinson; Stephanie Halford; Katharine R Owen; Timothy M Frayling; Mark Walker; Graham A Hitman; Jonathan C Levy; Mike J Sampson; Edith J M Feskens; Andrew T Hattersley; Mark I McCarthy
Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset.
Diabetes 2004;53(12):3319-22.
2004: Eleftheria Zeggini; Anthony M Reginato; A Prais; W Thomson; William McLean; Rachelle Donn
Linkage and association studies of discoidin domain receptor 1 (DDR1) single nucleotide polymorphisms (SNPs) in juvenile oligoarthritis.
Rheumatology (Oxford, England) 2004;43(9):1138-41.
2004: Sally John; Neil Shephard; Guoying Liu; Eleftheria Zeggini; Manqiu Cao; Wenwei Chen; Nisha Vasavda; Tracy Mills; Anne Barton; Anne Hinks; Stephen Eyre; Keith W Jones; W E R Ollier; Alan Silman; Neil Gibson; Jane Worthington; Giulia C Kennedy
Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites.
American journal of human genetics 2004;75(1):54-64.
2004: Rachelle Donn; Zaynab Alourfi; Eleftheria Zeggini; Rebecca Lamb; Francine Jury; Mark Lunt; Cristina Meazza; de benedetti fabrizio; Wendy Thomson; David Ray
A functional promoter haplotype of macrophage migration inhibitory factor is linked and associated with juvenile idiopathic arthritis.
Arthritis and rheumatism 2004;50(5):1604-10.
2004: Anne Barton; H Platt; Fiona Salway; Deborah Symmons; E Barrett; Marwan Bukhari; Mark Lunt; Eleftheria Zeggini; Stephen Eyre; Anne Hinks; DJ Tellam; B Brintnell; W E R Ollier; Jane Worthington; Alan Silman
Polymorphisms in the tumour necrosis factor gene are not associated with severity of inflammatory polyarthritis.
Annals of the rheumatic diseases 2004;63(3):280-4.
2004: Adam Stevens; David W Ray; Eleftheria Zeggini; Sally John; Helen L Richards; Christopher E M Griffiths; Rachelle Donn
Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype.
The Journal of clinical endocrinology and metabolism 2004;89(2):892-7.
2003: Neil Shephard; Milena Falcaro; Eleftheria Zeggini; Philip Chapman; Anne Hinks; Anne Barton; Jane Worthington; Andrew Pickles; Sally John
Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure.
BMC genetics 2003;4 Suppl 1():S26.
2002: Eleftheria Zeggini; Wendy Thomson; Dominic Kwiatkowski; Anna Richardson; W E R Ollier; Rachelle Donn
Linkage and association studies of single-nucleotide polymorphism-tagged tumor necrosis factor haplotypes in juvenile oligoarthritis.
Arthritis and rheumatism 2002;46(12):3304-11.
2002: Eleftheria Zeggini; Rachelle Donn; W E R Ollier; Wendy Thomson
Evidence for linkage of HLA loci in juvenile idiopathic oligoarthritis: independent effects of HLA-A and HLA-DRB1.
Arthritis and rheumatism 2002;46(10):2716-20.
2002: Rachelle Donn; Zaynab Alourfi; de benedetti fabrizio; Cristina Meazza; Eleftheria Zeggini; Mark Lunt; Adam Stevens; Emma Shelley; Rebecca Lamb; W E R Ollier; Wendy Thomson; David Ray
Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis.
Arthritis and rheumatism 2002;46(9):2402-9.
2002: Eleftheria Zeggini; Wendy Thomson; Aliya Alansari; W E R Ollier; Rachelle Donn
Tumour necrosis factor receptor II polymorphism and juvenile idiopathic arthritis.
Rheumatology (Oxford, England) 2002;41(4):462-5.
2002: Rachelle Donn; Eleftheria Zeggini; Emma Shelley; W E R Ollier; Wendy Thomson
Lack of association between juvenile idiopathic arthritis and fas gene polymorphism.
The Journal of rheumatology 2002;29(1):166-8.
2001: Janet A Dixon; I Reynolds; Eleftheria Zeggini; Andrew B Tullo; M Chantal Hillarby
Fas mRNA expression in blood is reduced during episodes of human corneal graft rejection.
Transplantation 2001;71(5):702-5.