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Steven Zeisel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Disorders

Choline Deficiency

Anatomy

Liver
Brain

Living Beings

Physiology

Objects

Diet

Concepts & Ideas

Nutritional Requirements

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Co-Publications
Name
34
Mar, Mei-Heng
22
da Costa, Kerry-Ann
18
Albright, Craig
13
Craciunescu, Corneliu
11
Fischer, Leslie
10
Niculescu, Mihai
8
Kohlmeier, Martin
8
Salganik, Rudolf
6
Stabler, Sally
5
Song, Jiannan
5
Wagner, Conrad
5
Shin, OH
5
Mudd, Harvey
5
Garner, Sanford
5
Allen, Robert

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Publications

TOP 3
Zeisel Steven H; da Costa Kerry-Ann
Choline: an essential nutrient for public health.
Xu Xinran; Gammon Marilie D; Zeisel Steven H; Bradshaw Patrick T; Wetmur James G; Teitelbaum Susan L; Neugut Alfred I; Santella Regina M; Chen Jia
High intakes of choline and betaine reduce breast cancer mortality in a population-based study.
Rosales Francisco J; Reznick J Steven; Zeisel Steven H
Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers.

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All Publications

2009: Zeisel Steven H; da Costa Kerry-Ann
Choline: an essential nutrient for public health.
Nutrition reviews 2009;67(11):615-23.
2009: Xu Xinran; Gammon Marilie D; Zeisel Steven H; Bradshaw Patrick T; Wetmur James G; Teitelbaum Susan L; Neugut Alfred I; Santella Regina M; Chen Jia
High intakes of choline and betaine reduce breast cancer mortality in a population-based study.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(11):4022-8.
2009: Rosales Francisco J; Reznick J Steven; Zeisel Steven H
Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers.
Nutritional neuroscience 2009;12(5):190-202.
2009: Zeisel Steven H
Epigenetic mechanisms for nutrition determinants of later health outcomes.
The American journal of clinical nutrition 2009;89(5):1488S-1493S.
2009: Xu Xinran; Gammon Marilie D; Zhang Yujing; Bestor Timothy H; Zeisel Steven H; Wetmur James G; Wallenstein Sylvan; Bradshaw Patrick T; Garbowski Gail; Teitelbaum Susan L; Neugut Alfred I; Santella Regina M; Chen Jia
BRCA1 promoter methylation is associated with increased mortality among women with breast cancer.
Breast cancer research and treatment 2009;115(2):397-404.
2009: Zeisel Steven H
Importance of methyl donors during reproduction.
The American journal of clinical nutrition 2009;89(2):673S-7S.
2009: Zeisel Steven H
Is maternal diet supplementation beneficial? Optimal development of infant depends on mother's diet.
The American journal of clinical nutrition 2009;89(2):685S-7S.
2008: Zeisel Steven H
Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models.
Brain research 2008;1237():5-11.
2008: Pop Elena A; Fischer Leslie M; Coan April D; Gitzinger Matt; Nakamura Jun; Zeisel Steven H
Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trial.
Menopause (New York, N.Y.) 2008;15(4 Pt 1):684-92.
2008: Rosales Francisco J; Zeisel Steven H
Perspectives from the symposium: The role of nutrition in infant and toddler brain and behavioral development.
Nutritional neuroscience 2008;11(3):135-43.
2008: Xu Xinran; Gammon Marilie D; Zeisel Steven H; Lee Yin Leng; Wetmur James G; Teitelbaum Susan L; Bradshaw Patrick T; Neugut Alfred I; Santella Regina M; Chen Jia
Choline metabolism and risk of breast cancer in a population-based study.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(6):2045-52.
2008: Zeisel Steven H
Is there a new component of the Mediterranean diet that reduces inflammation?
The American journal of clinical nutrition 2008;87(2):277-8.
2008: Gossell-Williams Maxine; Fletcher Horace; Zeisel Steven H
Unexpected depletion in plasma choline and phosphatidylcholine concentrations in a pregnant woman with bipolar affective disorder being treated with lithuim, haloperidol and benztropine: a case report.
Journal of medical case reports 2008;2():55.
2007: Chiuve Stephanie E; Giovannucci Edward L; Hankinson Susan E; Zeisel Steven H; Dougherty Lauren W; Willett Walter C; Rimm Eric B
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
The American journal of clinical nutrition 2007;86(4):1073-81.
2007: Zeisel Steven H
Nutrigenomics and metabolomics will change clinical nutrition and public health practice: insights from studies on dietary requirements for choline.
The American journal of clinical nutrition 2007;86(3):542-8.
2007: Cho Eunyoung; Willett Walter C; Colditz Graham A; Fuchs Charles S; Wu Kana; Chan Andrew T; Zeisel Steven H; Giovannucci Edward L
Dietary choline and betaine and the risk of distal colorectal adenoma in women.
Journal of the National Cancer Institute 2007;99(16):1224-31.
2007: Resseguie Mary; Song Jiannan; Niculescu Mihai D; da Costa Kerry-Ann; Randall Thomas A; Zeisel Steven H
Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(10):2622-32.
2007: Niculescu Mihai D; da Costa Kerry-Ann; Fischer Leslie M; Zeisel Steven H
Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not.
The American journal of clinical nutrition 2007;86(1):230-9.
2007: Zeisel Steven H
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline.
IUBMB life 2007;59(6):380-7.
2007: Niculescu Mihai D; Pop Elena A; Fischer Leslie M; Zeisel Steven H
Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not.
The Journal of nutritional biochemistry 2007;18(6):380-90.
2007: Fischer Leslie M; daCosta Kerry Ann; Kwock Lester; Stewart Paul W; Lu Tsui-Shan; Stabler Sally P; Allen Robert H; Zeisel Steven H
Sex and menopausal status influence human dietary requirements for the nutrient choline.
The American journal of clinical nutrition 2007;85(5):1275-85.
2007: Steck Susan E; Gammon Marilie D; Hebert James R; Wall Denise E; Zeisel Steven H
GSTM1, GSTT1, GSTP1, and GSTA1 polymorphisms and urinary isothiocyanate metabolites following broccoli consumption in humans.
The Journal of nutrition 2007;137(4):904-9.
2007: Couch Marion; Lai Victor; Cannon Trinitia; Guttridge Denis; Zanation Adam; George Jonathan; Hayes D Neil; Zeisel Steven; Shores Carol
Cancer cachexia syndrome in head and neck cancer patients: part I. Diagnosis, impact on quality of life and survival, and treatment.
Head & neck 2007;29(4):401-11.
2007: Niculescu Mihai D; Wu Renan; Guo Zhong; da Costa Kerry Ann; Zeisel Steven H
Diethanolamine alters proliferation and choline metabolism in mouse neural precursor cells.
Toxicological sciences : an official journal of the Society of Toxicology 2007;96(2):321-6.
2007: Bidulescu Aurelian; Chambless Lloyd E; Siega-Riz Anna Maria; Zeisel Steven H; Heiss Gerardo
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study.
BMC cardiovascular disorders 2007;7():20.
2006: Zeisel Steven H
The fetal origins of memory: the role of dietary choline in optimal brain development.
The Journal of pediatrics 2006;149(5 Suppl):S131-6.
2006: Craciunescu Corneliu N; Wu Renan; Zeisel Steven H
Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(10):1635-40.
2006: Buist N R M; Glenn B; Vugrek O; Wagner C; Stabler S; Allen R H; Pogribny I; Schulze A; Zeisel S H; Baric I; Mudd S H
S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man.
Journal of inherited metabolic disease 2006;29(4):538-45.
2006: da Costa Kerry-Ann; Niculescu Mihai D; Craciunescu Corneliu N; Fischer Leslie M; Zeisel Steven H
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans.
The American journal of clinical nutrition 2006;84(1):88-94.
2006: da Costa Kerry-Ann; Kozyreva Olga G; Song Jiannan; Galanko Joseph A; Fischer Leslie M; Zeisel Steven H
Common genetic polymorphisms affect the human requirement for the nutrient choline.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1336-44.
2006: Zeisel Steven H; Niculescu Mihai D
Perinatal choline influences brain structure and function.
Nutrition reviews 2006;64(4):197-203.
2006: Lindell Karen C; Adams Kelly M; Kohlmeier Martin; Zeisel Steven H
The evolution of Nutrition in Medicine, a computer-assisted nutrition curriculum.
The American journal of clinical nutrition 2006;83(4):956S-962S.
2006: Adams Kelly M; Lindell Karen C; Kohlmeier Martin; Zeisel Steven H
Status of nutrition education in medical schools.
The American journal of clinical nutrition 2006;83(4):941S-944S.
2006: Cho Eunyoung; Zeisel Steven H; Jacques Paul; Selhub Jacob; Dougherty Lauren; Colditz Graham A; Willett Walter C
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
The American journal of clinical nutrition 2006;83(4):905-11.
2006: Zeisel Steven H
Betaine supplementation and blood lipids: fact or artifact?
Nutrition reviews 2006;64(2 Pt 1):77-9.
2006: Niculescu Mihai D; Craciunescu Corneliu N; Zeisel Steven H
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):43-9.
2006: Zeisel Steven H
Choline: critical role during fetal development and dietary requirements in adults.
Annual review of nutrition 2006;26():229-50.
2005: Wijekoon Enoka P; Hall Beatrice; Ratnam Shobhitha; Brosnan Margaret E; Zeisel Steven H; Brosnan John T
Homocysteine metabolism in ZDF (type 2) diabetic rats.
Diabetes 2005;54(11):3245-51.
2005: Kohlmeier Martin; da Costa Kerry-Ann; Fischer Leslie M; Zeisel Steven H
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):16025-30.
2005: Zeisel Steven H
Choline, homocysteine, and pregnancy.
The American journal of clinical nutrition 2005;82(4):719-20.
2005: Albright Craig D; Mar Mei-Heng; Craciunescu Corneliu N; Song Jiannan; Zeisel Steven H
Maternal dietary choline availability alters the balance of netrin-1 and DCC neuronal migration proteins in fetal mouse brain hippocampus.
Brain research. Developmental brain research 2005;159(2):149-54.
2005: Song Jiannan; da Costa Kerry Ann; Fischer Leslie M; Kohlmeier Martin; Kwock Lester; Wang Shuli; Zeisel Steven H
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD).
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1266-71.
2005: Niculescu Mihai D; Craciunescu Corneliu N; Zeisel Steven H
Gene expression profiling of choline-deprived neural precursor cells isolated from mouse brain.
Brain research. Molecular brain research 2005;134(2):309-22.
2005: Zhu Xiaonan; Zeisel Steven H
Gene expression profiling in phosphatidylethanolamine N-methyltransferase knockout mice.
Brain research. Molecular brain research 2005;134(2):239-55.
2005: Fischer Leslie M; Scearce Julie A; Mar Mei-Heng; Patel Jayanti R; Blanchard Renee T; Macintosh Beth A; Busby Marjorie G; Zeisel Steven H
Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level.
The Journal of nutrition 2005;135(4):826-9.
2005: da Costa Kerry-Ann; Gaffney Christopher E; Fischer Leslie M; Zeisel Steven H
Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load.
The American journal of clinical nutrition 2005;81(2):440-4.
2005: Baric I; Cuk M; Fumic K; Vugrek O; Allen R H; Glenn B; Maradin M; Pazanin L; Pogribny I; Rados M; Sarnavka V; Schulze A; Stabler S; Wagner C; Zeisel S H; Mudd S H
S-Adenosylhomocysteine hydrolase deficiency: a second patient, the younger brother of the index patient, and outcomes during therapy.
Journal of inherited metabolic disease 2005;28(6):885-902.
2005: Albright Craig D; da Costa Kerry-Ann; Craciunescu Corneliu N; Klem Erich; Mar Mei-Heng; Zeisel Steven H
Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2005;15(1-4):59-68.
2004: Zeisel Steven H
Nutritional importance of choline for brain development.
Journal of the American College of Nutrition 2004;23(6 Suppl):621S-626S.
2004: Siega-Riz Anna Maria; Savitz David A; Zeisel Steven H; Thorp John M; Herring Amy
Second trimester folate status and preterm birth.
American journal of obstetrics and gynecology 2004;191(6):1851-7.
2004: Busby Marjorie G; Fischer Leslie; da Costa Kerry-Ann; Thompson Dorothene; Mar Mei-Heng; Zeisel Steven H
Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria.
Journal of the American Dietetic Association 2004;104(12):1836-45.
2004: Zeisel Steven H
Antioxidants suppress apoptosis.
The Journal of nutrition 2004;134(11):3179S-3180S.
2004: da Costa Kerry-Ann; Badea Mihaela; Fischer Leslie M; Zeisel Steven H
Elevated serum creatine phosphokinase in choline-deficient humans: mechanistic studies in C2C12 mouse myoblasts.
The American journal of clinical nutrition 2004;80(1):163-70.
2004: Niculescu Mihai D; Yamamuro Yutaka; Zeisel Steven H
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene.
Journal of neurochemistry 2004;89(5):1252-9.
2004: Schwahn Bernd C; Wendel Udo; Lussier-Cacan Suzanne; Mar Mei-Heng; Zeisel Steven H; Leclerc Daniel; Castro Carmen; Garrow Timothy A; Rozen Rima
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency.
Metabolism: clinical and experimental 2004;53(5):594-9.
2004: Zhu Xiaonan; Mar Mei-Heng; Song Jiannan; Zeisel Steven H
Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus.
Brain research. Developmental brain research 2004;149(2):121-9.
2004: Baric Ivo; Fumic Ksenija; Glenn Byron; Cuk Mario; Schulze Andreas; Finkelstein James D; James S Jill; Mejaski-Bosnjak Vlatka; Pazanin Leo; Pogribny Igor P; Rados Marko; Sarnavka Vladimir; Scukanec-Spoljar Mira; Allen Robert H; Stabler Sally; Uzelac Lidija; Vugrek Oliver; Wagner Conrad; Zeisel Steven; Mudd S Harvey
S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4234-9.
2004: Craciunescu Corneliu N; Brown Elliott C; Mar Mei-Heng; Albright Craig D; Nadeau Marie R; Zeisel Steven H
Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain.
The Journal of nutrition 2004;134(1):162-6.
2004: Fischer Leslie; Mahoney Chrysa; Jeffcoat A Robert; Koch Matthew A; Thomas Brian E; Valentine John L; Stinchcombe Thomas; Boan Jarol; Crowell James A; Zeisel Steven H
Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia.
Nutrition and cancer 2004;48(2):160-70.
2003: Norman Helen A; Butrum Ritva R; Feldman Elaine; Heber David; Nixon Daniel; Picciano Mary Frances; Rivlin Richard; Simopoulos Artemis; Wargovich Michael J; Weisburger Elizabeth K; Zeisel Steven H
The role of dietary supplements during cancer therapy.
The Journal of nutrition 2003;133(11 Suppl 1):3794S-3799S.
2003: Craciunescu Corneliu N; Albright Craig D; Mar Mei-Heng; Song Jiannan; Zeisel Steven H
Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus.
The Journal of nutrition 2003;133(11):3614-8.
2003: Watkins Steven M; Zhu Xiaonan; Zeisel Steven H
Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice.
The Journal of nutrition 2003;133(11):3386-91.
2003: Zeisel Steven H; Mar Mei-Heng; Howe Juliette C; Holden Joanne M
Concentrations of choline-containing compounds and betaine in common foods.
The Journal of nutrition 2003;133(5):1302-7.
2003: Albright Craig D; Salganik Rudolf I; Craciunescu Corneliu N; Mar Mei-Heng; Zeisel Steven H
Mitochondrial and microsomal derived reactive oxygen species mediate apoptosis induced by transforming growth factor-beta1 in immortalized rat hepatocytes.
Journal of cellular biochemistry 2003;89(2):254-61.
2003: Albright Craig D; Siwek Donald F; Craciunescu Corneliu N; Mar Mei-Heng; Kowall Neil W; Williams Christina L; Zeisel Steven H
Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus.
Nutritional neuroscience 2003;6(2):129-34.
2003: Kohlmeier Martin; McConathy Walter J; Cooksey Lindell Karen; Zeisel Steven H
Adapting the contents of computer-based instruction based on knowledge tests maintains effectiveness of nutrition education.
The American journal of clinical nutrition 2003;77(4 Suppl):1025S-1027S.
2003: Miltyk Woytek; Craciunescu Corneliu N; Fischer Leslie; Jeffcoat Robert A; Koch Matthew A; Lopaczynski Wlodek; Mahoney Chrysa; Jeffcoat Robert A; Crowell James; Paglieri Jennifer; Zeisel Steven H
Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer.
The American journal of clinical nutrition 2003;77(4):875-82.
2003: Schwahn Bernd C; Chen Zhoutao; Laryea Maurice D; Wendel Udo; Lussier-Cacan Suzanne; Genest Jacques; Mar Mei-Heng; Zeisel Steven H; Castro Carmen; Garrow Timothy; Rozen Rima
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(3):512-4.
2003: Zhu Xiaonan; Song Jiannan; Mar Mei-Heng; Edwards Lloyd J; Zeisel Steven H
Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline.
The Biochemical journal 2003;370(Pt 3):987-93.
2003: Mudd S H; Tangerman A; Stabler S P; Allen R H; Wagner C; Zeisel S H; Levy H L
Maternal methionine adenosyltransferase I/III deficiency: reproductive outcomes in a woman with four pregnancies.
Journal of inherited metabolic disease 2003;26(5):443-58.
2002: Bloedon LeAnne T; Jeffcoat A Robert; Lopaczynski Wlodek; Schell Michael J; Black Tracy M; Dix Kelly J; Thomas Brian F; Albright Craig; Busby Marjorie G; Crowell James A; Zeisel Steven H
Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women.
The American journal of clinical nutrition 2002;76(5):1126-37.
2002: Koc Hasan; Mar Mei-Heng; Ranasinghe Asoka; Swenberg James A; Zeisel Steven H
Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry.
Analytical chemistry 2002;74(18):4734-40.
2002: Niculescu Mihai D; Zeisel Steven H
Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline.
The Journal of nutrition 2002;132(8 Suppl):2333S-2335S.
2002: Yen Chi-Liang E; Mar Mei-Heng; Craciunescu Corneliu N; Edwards Lloyd J; Zeisel Steven H
Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells.
The Journal of nutrition 2002;132(7):1840-7.
2002: Cottington E M; LaMantia Christian; Stabler Sally P; Allen Robert H; Tangerman Albert; Wagner Conrad; Zeisel Steven H; Mudd S Harvey
Adverse event associated with methionine loading test: a case report.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):1046-50.
2002: Lehman-McKeeman Lois D; Gamsky Elizabeth A; Hicks Sarah M; Vassallo Jeffrey D; Mar Mei-Heng; Zeisel Steven H
Diethanolamine induces hepatic choline deficiency in mice.
Toxicological sciences : an official journal of the Society of Toxicology 2002;67(1):38-45.
2002: Fisher Melanie C; Zeisel Steven H; Mar Mei-Heng; Sadler Thomas W
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):619-21.
2002: Buchowski Maciej S; Plaisted Claudia; Fort Jane; Zeisel Steven H
Computer-assisted teaching of nutritional anemias and diabetes to first-year medical students.
The American journal of clinical nutrition 2002;75(1):154-61.
2002: Busby Marjorie G; Jeffcoat A Robert; Bloedon LeAnne T; Koch Matthew A; Black Tracy; Dix Kelly J; Heizer William D; Thomas Brian F; Hill Judith M; Crowell James A; Zeisel Steven H
Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men.
The American journal of clinical nutrition 2002;75(1):126-36.
2001: Thomas B F; Zeisel S H; Busby M G; Hill J M; Mitchell R A; Scheffler N M; Brown S S; Bloeden L T; Dix K J; Jeffcoat A R
Quantitative analysis of the principle soy isoflavones genistein, daidzein and glycitein, and their primary conjugated metabolites in human plasma and urine using reversed-phase high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Biomedical sciences and applications 2001;760(2):191-205.
2001: Vrablic A S; Albright C D; Craciunescu C N; Salganik R I; Zeisel S H
Altered mitochondrial function and overgeneration of reactive oxygen species precede the induction of apoptosis by 1-O-octadecyl-2-methyl-rac-glycero-3-phosphocholine in p53-defective hepatocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1739-44.
2001: Yen C L; Mar M H; Meeker R B; Fernandes A; Zeisel S H
Choline deficiency induces apoptosis in primary cultures of fetal neurons.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1704-10.
2001: Fisher M C; Zeisel S H; Mar M H; Sadler T W
Inhibitors of choline uptake and metabolism cause developmental abnormalities in neurulating mouse embryos.
Teratology 2001;64(2):114-22.
2001: Albright C D; Mar M H; Friedrich C B; Brown E C; Zeisel S H
Maternal choline availability alters the localization of p15Ink4B and p27Kip1 cyclin-dependent kinase inhibitors in the developing fetal rat brain hippocampus.
Developmental neuroscience 2001;23(2):100-6.
2000: Zeisel S H
Choline: needed for normal development of memory.
Journal of the American College of Nutrition 2000;19(5 Suppl):528S-531S.
2000: Cooksey K; Kohlmeier M; Plaisted C; Adams K; Zeisel S H
Getting nutrition education into medical schools: a computer-based approach.
The American journal of clinical nutrition 2000;72(3 Suppl):868S-76S.
2000: Zeisel S H
Is there a metabolic basis for dietary supplementation?
The American journal of clinical nutrition 2000;72(2 Suppl):507S-11S.
2000: Zeisel S H
Choline: an essential nutrient for humans.
Nutrition (Burbank, Los Angeles County, Calif.) 2000;16(7-8):669-71.
2000: Salganik R I; Albright C D; Rodgers J; Kim J; Zeisel S H; Sivashinskiy M S; Van Dyke T A
Dietary antioxidant depletion: enhancement of tumor apoptosis and inhibition of brain tumor growth in transgenic mice.
Carcinogenesis 2000;21(5):909-14.
2000: Kohlmeier M; Althouse L; Stritter F; Zeisel S H
Introducing cancer nutrition to medical students: effectiveness of computer-based instruction.
The American journal of clinical nutrition 2000;71(4):873-7.
2000: Plaisted C S; Kohlmeier M; Cooksey K; Zeisel S H
The development of "Nutrition in Medicine" interactive CD-ROM programs for medical nutrition education.
Journal of cancer education : the official journal of the American Association for Cancer Education 2000;15(3):140-3.
1999: Mar M H; Zeisel S H
Betaine in wine: answer to the French paradox?
Medical hypotheses 1999;53(5):383-5.
1999: Albright C D; Friedrich C B; Brown E C; Mar M H; Zeisel S H
Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum.
Brain research. Developmental brain research 1999;115(2):123-9.
1999: Zeisel S H; Plaisted C S
CD-ROMs for nutrition education.
Journal of the American College of Nutrition 1999;18(3):287.
1999: Albright C D; Tsai A Y; Friedrich C B; Mar M H; Zeisel S H
Choline availability alters embryonic development of the hippocampus and septum in the rat.
Brain research. Developmental brain research 1999;113(1-2):13-20.
1999: Zeisel S H; Salganik R I
Antioxidants and nutrition support.
Current opinion in clinical nutrition and metabolic care 1999;2(1):1-3.
1999: Yen C L; Mar M H; Zeisel S H
Choline deficiency-induced apoptosis in PC12 cells is associated with diminished membrane phosphatidylcholine and sphingomyelin, accumulation of ceramide and diacylglycerol, and activation of a caspase.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(1):135-42.
1998: Albright C D; Zeisel S H; Salganik R I
Choline deficiency induces apoptosis and decreases the number of eosinophilic preneoplastic foci in the liver of OXYS rats.
Pathobiology : journal of immunopathology, molecular and cellular biology 1998;66(2):71-6.
1997: Savendahl L; Mar M H; Underwood L E; Zeisel S H
Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction.
The American journal of clinical nutrition 1997;66(3):622-5.
1997: Shin O H; da Costa K A; Mar M H; Zeisel S H
Hepatic protein kinase C is not activated despite high intracellular 1,2-sn-diacylglycerol in obese Zucker rats.
Biochimica et biophysica acta 1997;1358(1):72-8.
1997: Zeisel S H; Albright C D; Shin O H; Mar M H; Salganik R I; da Costa K A
Choline deficiency selects for resistance to p53-independent apoptosis and causes tumorigenic transformation of rat hepatocytes.
Carcinogenesis 1997;18(4):731-8.
1997: Shin O H; Mar M H; Albright C D; Citarella M T; da Costa K A; Zeisel S H
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency.
Journal of cellular biochemistry 1997;64(2):196-208.
1997: Albright C D; Zeisel S H
Choline deficiency causes increased localization of transforming growth factor-beta1 signaling proteins and apoptosis in the rat liver.
Pathobiology : journal of immunopathology, molecular and cellular biology 1997;65(5):264-70.
1997: Albright C D; Liu R; Mar M H; Shin O H; Vrablic A S; Salganik R I; Zeisel S H
Diet, apoptosis, and carcinogenesis.
Advances in experimental medicine and biology 1997;422():97-107.
1997: Zeisel S H
Choline: essential for brain development and function.
Advances in pediatrics 1997;44():263-95.
1996: Holmes-McNary M Q; Cheng W L; Mar M H; Fussell S; Zeisel S H
Choline and choline esters in human and rat milk and in infant formulas.
The American journal of clinical nutrition 1996;64(4):572-6.
1996: Albright C D; Liu R; Bethea T C; Da Costa K A; Salganik R I; Zeisel S H
Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(4):510-6.
1996: Zeisel S H
Choline. A nutrient that is involved in the regulation of cell proliferation, cell death, and cell transformation.
Advances in experimental medicine and biology 1996;399():131-41.
1995: Zeisel S H; Mar M H; Zhou Z; da Costa K A
Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver.
The Journal of nutrition 1995;125(12):3049-54.
1995: Garner S C; Mar M H; Zeisel S H
Choline distribution and metabolism in pregnant rats and fetuses are influenced by the choline content of the maternal diet.
The Journal of nutrition 1995;125(11):2851-8.
1995: da Costa K A; Garner S C; Chang J; Zeisel S H
Effects of prolonged (1 year) choline deficiency and subsequent re-feeding of choline on 1,2-sn-diradylglycerol, fatty acids and protein kinase C in rat liver.
Carcinogenesis 1995;16(2):327-34.
1995: Zeisel S H; da Costa K A; Albright C D; Shin O H
Choline and hepatocarcinogenesis in the rat.
Advances in experimental medicine and biology 1995;375():65-74.
1995: Zeisel S H
Nutrients, signal transduction and carcinogenesis.
Advances in experimental medicine and biology 1995;369():175-83.
1994: Kim Y I; Miller J W; da Costa K A; Nadeau M; Smith D; Selhub J; Zeisel S H; Mason J B
Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver.
The Journal of nutrition 1994;124(11):2197-203.
1994: Zeisel S H; Blusztajn J K
Choline and human nutrition.
Annual review of nutrition 1994;14():269-96.
1993: Rohlfs E M; Louie D S; Zeisel S H
Lipid synthesis and secretion by primary cultures of rat mammary epithelial cells.
Journal of cellular physiology 1993;157(3):469-80.
1993: Rohlfs E M; Garner S C; Mar M H; Zeisel S H
Glycerophosphocholine and phosphocholine are the major choline metabolites in rat milk.
The Journal of nutrition 1993;123(10):1762-8.
1993: Garner S C; Chou S C; Mar M H; Coleman R A; Zeisel S H
Characterization of choline metabolism and secretion by human placental trophoblasts in culture.
Biochimica et biophysica acta 1993;1168(3):358-64.
1993: Zeisel S H
Choline phospholipids: signal transduction and carcinogenesis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(6):551-7.
1993: da Costa K A; Cochary E F; Blusztajn J K; Garner S C; Zeisel S H
Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline-deficient rats.
The Journal of biological chemistry 1993;268(3):2100-5.
1992: Zeisel S H
Choline: an important nutrient in brain development, liver function and carcinogenesis.
Journal of the American College of Nutrition 1992;11(5):473-81.
1992: Zhang J; Blusztajn J K; Zeisel S H
Measurement of the formation of betaine aldehyde and betaine in rat liver mitochondria by a high pressure liquid chromatography-radioenzymatic assay.
Biochimica et biophysica acta 1992;1117(3):333-9.
1991: Zeisel S H; Da Costa K A; Franklin P D; Alexander E A; Lamont J T; Sheard N F; Beiser A
Choline, an essential nutrient for humans.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(7):2093-8.
1990: Tayek J A; Bistrian B; Sheard N F; Zeisel S H; Blackburn G L
Abnormal liver function in malnourished patients receiving total parenteral nutrition: a prospective randomized study.
Journal of the American College of Nutrition 1990;9(1):76-83.
1989: Sheard N F; Zeisel S H
Choline: an essential dietary nutrient?
Nutrition (Burbank, Los Angeles County, Calif.) 1989;5(1):1-5.
1986: Sheard N F; Zeisel S H
An in vitro study of choline uptake by intestine from neonatal and adult rats.
Pediatric research 1986;20(8):768-72.
1986: Sheard N F; Tayek J A; Bistrian B R; Blackburn G L; Zeisel S H
Plasma choline concentration in humans fed parenterally.
The American journal of clinical nutrition 1986;43(2):219-24.
1986: Zeisel S H; Char D; Sheard N F
Choline, phosphatidylcholine and sphingomyelin in human and bovine milk and infant formulas.
The Journal of nutrition 1986;116(1):50-8.

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