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Zhaoshi Zeng

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Luc G Morris; Phillip Paty; Luke Peng; Deepa Ramaswami; Bhuvanesh Singh; David Solit; Efsevia Vakiani; Logan A Walsh; Zhaoshi Zeng; Yilong Zou; Şevin Turcan; Timothy C Cloughesy; Stephanie Eng; Ian Ganly; Yongxing Gong; Kasthuri Kannan; Andrew M Kaufman; Linda Liau; Ingo K Mellinghoff; Paul S Mischel; Victoria E Banuchi; Timothy Chan
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.
Yong H Wen; Zhaoshi Zeng; Muzaffar Akram; Edi Brogi; Jeff Catalano; Larry Norton; Philip B Paty; Jinru Shia
DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors.
Yevgeniy Karamurzin; Hikmat Al-Ahmadie; Daniel G Coit; Eileen M O'Reilly; Ihsane Ouansafi; Philip B Paty; Leonard B Saltz; Christine Sempoux; Jinru Shia; Robert A Soslow; Zsofia Kinga Stadler; Zhaoshi Zeng; Liying Zhang; David S Klimstra
Unusual DNA mismatch repair-deficient tumors in Lynch syndrome: a report of new cases and review of the literature.

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All Publications

2013: Luc G Morris; Phillip Paty; Luke Peng; Deepa Ramaswami; Bhuvanesh Singh; David Solit; Efsevia Vakiani; Logan A Walsh; Zhaoshi Zeng; Yilong Zou; Şevin Turcan; Timothy C Cloughesy; Stephanie Eng; Ian Ganly; Yongxing Gong; Kasthuri Kannan; Andrew M Kaufman; Linda Liau; Ingo K Mellinghoff; Paul S Mischel; Victoria E Banuchi; Timothy Chan
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.
Nature genetics 2013;45(3):253-61.
2012: Yong H Wen; Zhaoshi Zeng; Muzaffar Akram; Edi Brogi; Jeff Catalano; Larry Norton; Philip B Paty; Jinru Shia
DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors.
The American journal of surgical pathology 2012;36(11):1700-8.
2012: Yevgeniy Karamurzin; Hikmat Al-Ahmadie; Daniel G Coit; Eileen M O'Reilly; Ihsane Ouansafi; Philip B Paty; Leonard B Saltz; Christine Sempoux; Jinru Shia; Robert A Soslow; Zsofia Kinga Stadler; Zhaoshi Zeng; Liying Zhang; David S Klimstra
Unusual DNA mismatch repair-deficient tumors in Lynch syndrome: a report of new cases and review of the literature.
Human pathology 2012;43(10):1677-87.
2012: Efsevia Vakiani; Agnes Viale; Martin Weiser; Zhaoshi Zeng; Andrea Cercek Hanjis; Timothy Chan; Michael D'Angelica; Adriana Heguy; Manickam Janakiraman; Nancy Kemeny; Philip Paty; Leonard B Saltz; Ronglai Shen; Jinru Shia; Rileen Sinha; David B Solit
Comparative genomic analysis of primary versus metastatic colorectal carcinomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(24):2956-62.
2011: Thomas Bachleitner-Hofmann; Mark Y Sun; Chin-Tung Chen; David Liska; Zhaoshi Zeng; Agnes Viale; Adam B Olshen; Martina Mittlboeck; James G Christensen; Neal Rosen; David B Solit; Martin R Weiser
Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(1):122-33.
2010: Iyare Esemuede; Ann Forslund; Sajid A Khan; Li-Xuan Qin; Mark I Gimbel; Garrett M Nash; Zhaoshi Zeng; Shoshana Rosenberg; Jinru Shia; Francis Barany; Philip B Paty
Improved testing for microsatellite instability in colorectal cancer using a simplified 3-marker assay.
Annals of surgical oncology 2010;17(12):3370-8.
2010: Yu-Wei Cheng; Kamran Idrees; Richard Shattock; Sajid A Khan; Zhaoshi Zeng; Cameron Brennan; Philip B Paty; Francis Barany
Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer.
International journal of cancer. Journal international du cancer 2010;127(3):568-77.
2010: Manickam Janakiraman; Efsevia Vakiani; Zhaoshi Zeng; Christine A Pratilas; Barry S Taylor; Dhananjay Chitale; Ensar Halilovic; Manda Wilson; Kety Huberman; Julio Cezar Ricarte Filho; Yogindra Persaud; Douglas A Levine; James A Fagin; Suresh C Jhanwar; John M Mariadason; Alex E Lash; Marc Ladanyi; Leonard B Saltz; Adriana Heguy; Philip B Paty; David B Solit
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Cancer research 2010;70(14):5901-11.
2010: Garrett M Nash; Mark I Gimbel; Alfred M Cohen; Zhaoshi Zeng; Mackevin I Ndubuisi; Daniel R Nathanson; Jurg Ott; Francis Barany; Philip B Paty
KRAS mutation and microsatellite instability: two genetic markers of early tumor development that influence the prognosis of colorectal cancer.
Annals of surgical oncology 2010;17(2):416-24.
2010: Garrett M Nash; Mark I Gimbel; Jinru Shia; Daniel R Nathanson; MacKevin I Ndubuisi; Zhaoshi Zeng; Nancy Kemeny; Philip B Paty
KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases.
Annals of surgical oncology 2010;17(2):572-8.
2008: Thomas Bachleitner-Hofmann; Mark Y Sun; Chin-Tung Chen; Laura H Tang; Lin Song; Zhaoshi Zeng; Manish A Shah; James G Christensen; Neal Rosen; David B Solit; Martin R Weiser
HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells.
Molecular cancer therapeutics 2008;7(11):3499-508.
2008: Yu-Wei Cheng; Hanna Pincas; Manny Bacolod; Gunter Schemmann; Sarah F Giardina; Jianmin Huang; Sandra Barral; Kamran Idrees; Sajid A Khan; Zhaoshi Zeng; Shoshana Rosenberg; Daniel A Notterman; Jurg Ott; Philip B Paty; Francis Barany
CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(19):6005-13.
2008: Zhaoshi Zeng; Martin R Weiser; Eleanor Kuntz; Chin-Tung Chen; Sajid A Khan; Ann Forslund; Garrett M Nash; Mark Gimbel; Yuka Yamaguchi; Alfred T Culliford; Matthew D'Alessio; Francis Barany; Philip B Paty
c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases.
Cancer letters 2008;265(2):258-69.
2008: Sajid A Khan; Kamran Idrees; Ann Forslund; Zhaoshi Zeng; Shoshana Rosenberg; Hanna Pincas; Francis Barany; Kenneth Offit; Michael P LaQuaglia; Philip B Paty
Genetic variants in germline TP53 and MDM2 SNP309 are not associated with early onset colorectal cancer.
Journal of surgical oncology 2008;97(7):621-5.
2008: Manny Bacolod; Gunter S Schemmann; Shuang Wang; Richard Shattock; Sarah F Giardina; Zhaoshi Zeng; Jinru Shia; Robert F Stengel; Norman Gerry; Josephine Hoh; Tomas Kirchhoff; Bert Gold; Michael F Christman; Kenneth Offit; William L Gerald; Daniel A Notterman; Jurg Ott; Philip B Paty; Francis Barany
The signatures of autozygosity among patients with colorectal cancer.
Cancer research 2008;68(8):2610-21.
2008: Ann Forslund; Zhaoshi Zeng; Li-Xuan Qin; Shoshana Rosenberg; MacKevin Ndubuisi; Hanna Pincas; William Gerald; Daniel A Notterman; Francis Barany; Philip B Paty
MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers.
Molecular cancer research : MCR 2008;6(2):205-11.
2007: Udai S Kammula; Eleanor J Kuntz; Todd D Francone; Zhaoshi Zeng; Jinru Shia; Ron G Landmann; Philip B Paty; Martin R Weiser
Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome.
Cancer letters 2007;248(2):219-28.
2007: Todd D Francone; Ron G Landmann; Chin-Tung Chen; Mark Y Sun; Eleanor J Kuntz; Zhaoshi Zeng; Ronald P DeMatteo; Philip B Paty; Martin R Weiser
Novel xenograft model expressing human hepatocyte growth factor shows ligand-dependent growth of c-Met-expressing tumors.
Molecular cancer therapeutics 2007;6(4):1460-6.
2006: Dafna Tsafrir; Manny Bacolod; Zachariah Selvanayagam; Ilan Tsafrir; Jinru Shia; Zhaoshi Zeng; Hao Liu; Curtis Krier; Robert F Stengel; Francis Barany; William L Gerald; Philip B Paty; Eytan Domany; Daniel A Notterman
Relationship of gene expression and chromosomal abnormalities in colorectal cancer.
Cancer research 2006;66(4):2129-37.
2004: Zhaoshi Zeng; Martin R Weiser; Matthew D'Alessio; Andrew Grace; Jinru Shia; Philip B Paty
Immunoblot analysis of c-Met expression in human colorectal cancer: overexpression is associated with advanced stage cancer.
Clinical & experimental metastasis 2004;21(5):409-17.
2003: Garrett M Nash; Mark I Gimbel; Jinru Shia; Alfred T Culliford; Daniel R Nathanson; M Ndubuisi; Y Yamaguchi; Zhaoshi Zeng; Francis Barany; Philip B Paty
Automated, multiplex assay for high-frequency microsatellite instability in colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(16):3105-12.
2003: Daniel R Nathanson; Alfred T Culliford; Jinru Shia; Beiyun Chen; Matthew D'Alessio; Zhaoshi Zeng; Garrett M Nash; William Gerald; Francis Barany; Philip B Paty
HER 2/neu expression and gene amplification in colon cancer.
International journal of cancer. Journal international du cancer 2003;105(6):796-802.
2002: Zhaoshi Zeng; Wei-Ping Shu; Alfred M Cohen; Jose G Guillem
Matrix metalloproteinase-7 expression in colorectal cancer liver metastases: evidence for involvement of MMP-7 activation in human cancer metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):144-8.
2001: Zhaoshi Zeng; Yi Sun; W Shu; Jose G Guillem
Tissue inhibitor of metalloproteinase-3 is a basement membrane-associated protein that is significantly decreased in human colorectal cancer.
Diseases of the colon and rectum 2001;44(9):1290-6.
1999: S Mc Donnell; Vivek Chaudhry; J Mansilla-Soto; Zhaoshi Zeng; W P Shu; Jose G Guillem
Metastatic and non-metastatic colorectal cancer (CRC) cells induce host metalloproteinase production in vivo.
Clinical & experimental metastasis 1999;17(4):341-9.
1999: Zhaoshi Zeng; Alfred M Cohen; Jose G Guillem
Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis.
Carcinogenesis 1999;20(5):749-55.
1998: Zhaoshi Zeng; Jose G Guillem
Unique activation of matrix metalloproteinase-9 within human liver metastasis from colorectal cancer.
British journal of cancer 1998;78(3):349-53.
1996: Zhaoshi Zeng; Y Huang; Alfred M Cohen; Jose G Guillem
Prediction of colorectal cancer relapse and survival via tissue RNA levels of matrix metalloproteinase-9.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(12):3133-40.
1996: Zhaoshi Zeng; Jose G Guillem
Colocalisation of matrix metalloproteinase-9-mRNA and protein in human colorectal cancer stromal cells.
British journal of cancer 1996;74(8):1161-7.
1995: Zhaoshi Zeng; Jose G Guillem
Distinct pattern of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 mRNA expression in human colorectal cancer and liver metastases.
British journal of cancer 1995;72(3):575-82.
1995: Zhaoshi Zeng; Alfred M Cohen; Zuo-Feng Zhang; W Stetler-Stevenson; Jose G Guillem
Elevated tissue inhibitor of metalloproteinase 1 RNA in colorectal cancer stroma correlates with lymph node and distant metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(8):899-906.
1995: E Friedman; L I Gold; David S Klimstra; Zhaoshi Zeng; Sidney J Winawer; A Cohen
High levels of transforming growth factor beta 1 correlate with disease progression in human colon cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1995;4(5):549-54.
1995: Zhaoshi Zeng; Zuo-Feng Zhang; Elin R Sigurdson
Toxicity study of hepatic artery infusion chemotherapy with massive dose FUDR in rats.
Surgical oncology 1995;4(3):147-55.
1995: Zuo-Feng Zhang; Zhaoshi Zeng; Alvaro Sarkis; David S Klimstra; Elizabeth Charytonowicz; D Pollack; John Edward Vena; Jose G Guillem; J R Marshall; Carlos Cordon-Cardo
Family history of cancer, body weight, and p53 nuclear overexpression in Duke's C colorectal cancer.
British journal of cancer 1995;71(4):888-93.
1995: M Kuranami; CT Powell; H Hug; Zhaoshi Zeng; A M Cohen; Jose G Guillem
Differential expression of protein kinase C isoforms in human colorectal cancers.
The Journal of surgical research 1995;58(2):233-9.
1994: Zhaoshi Zeng; S Hsu; Zuo-Feng Zhang; Alfred M Cohen; Warren E Enker; A A Turnbull; Jose G Guillem
High level of Nm23-H1 gene expression is associated with local colorectal cancer progression not with metastases.
British journal of cancer 1994;70(5):1025-30.
1994: Zhaoshi Zeng; Alvaro Sarkis; Zuo-Feng Zhang; David S Klimstra; Elizabeth Charytonowicz; Jose G Guillem; Carlos Cordon-Cardo; Alfred M Cohen
p53 nuclear overexpression: an independent predictor of survival in lymph node--positive colorectal cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(10):2043-50.
1994: Z Zhang; A Aprikian; A Sarkis; Zhaoshi Zeng; D Pollack; C Cordoncardo; W Fair; C Begg
Factors associated with p53 nuclear accumulation in prostatic adenocarcinoma.
International journal of oncology 1994;4(4):897-902.
1993: Zhaoshi Zeng; Zuo-Feng Zhang
Cholecystectomy and colorectal cancer in China.
Surgical oncology 1993;2(6):311-9.
1993: Zhaoshi Zeng; Alfred M Cohen; C Urmacher
Usefulness of carcinoembryonic antigen monitoring despite normal preoperative values in node-positive colon cancer patients.
Diseases of the colon and rectum 1993;36(11):1063-8.
1992: Zhaoshi Zeng; Alfred M Cohen; S Hajdu; S S Sternberg; Elin R Sigurdson; Warren E Enker
Serosal cytologic study to determine free mesothelial penetration of intraperitoneal colon cancer.
Cancer 1992;70(4):737-40.