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Antonis Zervos

Research Profile

Chemicals & Drugs

Procedures

Two-Hybrid System Techniques

Living Beings

Mouse

Anatomy

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Publications

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S Kang; C P Landel; J-P Louboutin; D Martinez; D S Strayer; Antonis S Zervos; Pinaki Datta; Teresa Fernandes-Alnemri; Emad S Alnemri
Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging.
Camilla T Ambivero; Lucia Cilenti; Antonis S Zervos
ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway.
Lucia Cilenti; Meenakshi P Balakrishnan; Xiao-Liang Wang; Camilla Ambivero; Martin Sterlicchi; Federica del Monte; Xin L Ma; Antonis S Zervos
Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination.

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All Publications

2013: S Kang; C P Landel; J-P Louboutin; D Martinez; D S Strayer; Antonis S Zervos; Pinaki Datta; Teresa Fernandes-Alnemri; Emad S Alnemri
Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging.
Cell death and differentiation 2013;20(2):259-69.
2012: Camilla T Ambivero; Lucia Cilenti; Antonis S Zervos
ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway.
Biochimica et biophysica acta 2012;1823(12):2149-56.
2011: Lucia Cilenti; Meenakshi P Balakrishnan; Xiao-Liang Wang; Camilla Ambivero; Martin Sterlicchi; Federica del Monte; Xin L Ma; Antonis S Zervos
Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination.
Journal of molecular and cellular cardiology 2011;50(4):652-61.
2011: Meenakshi P Balakrishnan; Lucia Cilenti; Camilla Ambivero; Yamafumi Goto; Minoru Takata; James Turkson; Xiaoman Shawn Li; Antonis S Zervos
THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death.
Biochemical and biophysical research communications 2011;404(1):195-200.
2009: Meenakshi P Balakrishnan; Lucia Cilenti; Zineb Mashak; Paiyal Popat; Emad S Alnemri; Antonis S Zervos
THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.
American journal of physiology. Heart and circulatory physiology 2009;297(2):H643-53.
2007: J Althaus; MD Siegelin; Faramarz Dehghani; Lucia Cilenti; Antonis S Zervos; Abdelhaq Rami
The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion.
Neurochemistry international 2007;50(1):172-80.
2006: Anupama Kotha; Madhavi Sekharam; Lucia Cilenti; Khandaker Siddiquee; Annette Khaled; Antonis S Zervos; Bradford Carter; James Turkson; Richard Jove
Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.
Molecular cancer therapeutics 2006;5(3):621-9.
2005: Mangala M Soundarapandian; Wei Hong Tu; Peter L Peng; Antonis S Zervos; YouMing Lu
AMPA receptor subunit GluR2 gates injurious signals in ischemic stroke.
Molecular neurobiology 2005;32(2):145-55.
2005: Dirk M Hentschel; Kwon Moo Park; Lucia Cilenti; Antonis S Zervos; Iain Drummond; Joseph V Bonventre
Acute renal failure in zebrafish: a novel system to study a complex disease.
American journal of physiology. Renal physiology 2005;288(5):F923-9.
2005: Lucia Cilenti; George A Kyriazis; Mangala M Soundarapandian; Valerie Stratico; Adam Yerkes; Kwon Moo Park; Alice M Sheridan; Emad S Alnemri; Joseph V Bonventre; Antonis S Zervos
Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells.
American journal of physiology. Renal physiology 2005;288(2):F371-9.
2005: Hui-Rong Liu; Erhe Gao; Aihua Hu; Ling Tao; Yan Qu; Patrick Most; Walter J Koch; Theodore A Christopher; Bernard L Lopez; Emad S Alnemri; Antonis S Zervos; Xin L Ma
Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion.
Circulation 2005;111(1):90-6.
2004: Lucia Cilenti; Mangala M Soundarapandian; George A Kyriazis; Valerie Stratico; Supriya Singh; Sanjeev Gupta; Joseph V Bonventre; Emad S Alnemri; Antonis S Zervos
Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death.
The Journal of biological chemistry 2004;279(48):50295-301.
2004: Alessandra Trencia; Francesca Fiory; Maria Alessandra Maitan; Pasquale Vito; Alessia P. Barbagallo; Anna Perfetti; Claudia Miele; Paola Ungaro; Francesco Oriente; Lucia Cilenti; Antonis S Zervos; Pietro Formisano; Francesco Beguinot
Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15.
The Journal of biological chemistry 2004;279(45):46566-72.
2004: Sanjeev Gupta; Rajesh Singh; Pinaki Datta; Zhijia Zhang; Christopher Orr; Zhixian Lu; Garrett C DuBois; Antonis S Zervos; Miriam H Meisler; Srinivasa M Srinivasula; Teresa Fernandes-Alnemri; Emad S Alnemri
The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity.
The Journal of biological chemistry 2004;279(44):45844-54.
2003: Daniela Junqueira; Lucia Cilenti; Lucia Musumeci; John M Sedivy; Antonis S Zervos
Random mutagenesis of PDZ(Omi) domain and selection of mutants that specifically bind the Myc proto-oncogene and induce apoptosis.
Oncogene 2003;22(18):2772-81.
2003: Lucia Cilenti; Younghee Lee; Sibylle Hess; Srinivasa M Srinivasula; Kwon Moo Park; Daniela Junqueira; Hedvika Davis; Joseph V Bonventre; Emad S Alnemri; Antonis S Zervos
Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.
The Journal of biological chemistry 2003;278(13):11489-94.
2002: Ramesh Hegde; Srinivasa M Srinivasula; ZhiJia Zhang; Richard Wassell; Rula Mukattash; Lucia Cilenti; Garrett C DuBois; Yuri Lazebnik; Antonis S Zervos; Teresa Fernandes-Alnemri; Emad S Alnemri
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction.
The Journal of biological chemistry 2002;277(1):432-8.