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Dong Zhang

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Pengcheng Zhu; Denis Martinvalet; Dipanjan Chowdhury; Dong Zhang; Ann Schlesinger; Judy Lieberman
The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1.
Dong Zhang; Kathrin Zaugg; Tak W Mak; Stephen J Elledge
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response.
Dipanjan Chowdhury; Paul J Beresford; Pengcheng Zhu; Dong Zhang; Jung-Suk Sung; Bruce Demple; Fred W Perrino; Judy Lieberman
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.

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2009: Pengcheng Zhu; Denis Martinvalet; Dipanjan Chowdhury; Dong Zhang; Ann Schlesinger; Judy Lieberman
The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1.
Blood 2009;114(6):1205-16.
2006: Dong Zhang; Kathrin Zaugg; Tak W Mak; Stephen J Elledge
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response.
Cell 2006;126(3):529-42.
2006: Dipanjan Chowdhury; Paul J Beresford; Pengcheng Zhu; Dong Zhang; Jung-Suk Sung; Bruce Demple; Fred W Perrino; Judy Lieberman
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.
Molecular cell 2006;23(1):133-42.
2006: Pengcheng Zhu; Dong Zhang; Dipanjan Chowdhury; Denis Martinvalet; Dennis Keefe; Lianfa Shi; Judy Lieberman
Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70.
EMBO reports 2006;7(4):431-7.
2005: Hanping Feng; Dong Zhang; Deborah Palliser; Pengcheng Zhu; Shenghe Cai; Ann Schlesinger; Laura Maliszewski; Judy Lieberman
Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):421-32.
2005: Lianfa Shi; Dennis Keefe; Enrique Durand; Hanping Feng; Dong Zhang; Judy Lieberman
Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5456-61.
2003: Erwei Song; Sang-Kyung Lee; Derek M. Dykxhoorn; Carl D Novina; Dong Zhang; Keith Crawford; Jan Cerny; Phillip A Sharp; Judy Lieberman; N Manjunath; Premlata Shankar
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages.
Journal of virology 2003;77(13):7174-81.
2003: Zusen Fan; Paul J Beresford; David Y Oh; Dong Zhang; Judy Lieberman
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.
Cell 2003;112(5):659-72.
2003: Zusen Fan; Paul J Beresford; Dong Zhang; Zhan Xu; Carl D Novina; Akira Yoshida; Yves Pommier; Judy Lieberman
Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A.
Nature immunology 2003;4(2):145-53.
2003: Dong Zhang; Premlata Shankar; Zhan Xu; Brooke Harnisch; Gang Chen; Christoph Lange; Sandra Lee; Hernan Valdez; Michael M Lederman; Judy Lieberman
Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic.
Blood 2003;101(1):226-35.
2002: Zusen Fan; Paul J Beresford; Dong Zhang; Judy Lieberman
HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.
Molecular and cellular biology 2002;22(8):2810-20.
2001: Paul J Beresford; Dong Zhang; D Y Oh; Zusen Fan; E L Greer; M L Russo; M Jaju; Judy Lieberman
Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks.
The Journal of biological chemistry 2001;276(46):43285-93.
2001: Dong Zhang; Paul J Beresford; AH Greenberg; Judy Lieberman
Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5746-51.
2001: Dong Zhang; MS Pasternack; Paul J Beresford; L Wagner; AH Greenberg; Judy Lieberman
Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.
The Journal of biological chemistry 2001;276(5):3683-90.
2001: Dong Zhang; N Abovich; Michael Rosbash
A biochemical function for the Sm complex.
Molecular cell 2001;7(2):319-29.
1999: Dong Zhang; Michael Rosbash
Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex.
Genes & development 1999;13(5):581-92.
1997: Françoise Stutz; J Kantor; Dong Zhang; T McCarthy; M Neville; Michael Rosbash
The yeast nucleoporin rip1p contributes to multiple export pathways with no essential role for its FG-repeat region.
Genes & development 1997;11(21):2857-68.