Huang-Ge Zhang

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Deng Zhong-bin; Liu Yuelong; Liu Cunren; Xiang Xiaoyu; Wang Jianhua; Cheng Ziqiang; Shah Spandan V; Zhang Shuangyin; Zhang Liming; Zhuang Xiaoying; Michalek Sue; Grizzle William E; Zhang Huang-Ge
Immature myeloid cells induced by a high-fat diet contribute to liver inflammation.
Deng Zhong-bin; Poliakov Anton; Hardy Robert W; Clements Ronald; Liu Cunren; Liu Yuelong; Wang Jianhua; Xiang Xiaoyu; Zhang Shuangqin; Zhuang Xiaoying; Shah Spandan V; Sun Dongmei; Michalek Sue; Grizzle William E; Garvey Timothy; Mobley Jim; Zhang Huang-Ge
Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance.
Xiang Xiaoyu; Poliakov Anton; Liu Cunren; Liu Yuelong; Deng Zhong-bin; Wang Jianhua; Cheng Ziqiang; Shah Spandan V; Wang Gui-Jun; Zhang Liming; Grizzle William E; Mobley Jim; Zhang Huang-Ge
Induction of myeloid-derived suppressor cells by tumor exosomes.

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2009: Deng Zhong-bin; Liu Yuelong; Liu Cunren; Xiang Xiaoyu; Wang Jianhua; Cheng Ziqiang; Shah Spandan V; Zhang Shuangyin; Zhang Liming; Zhuang Xiaoying; Michalek Sue; Grizzle William E; Zhang Huang-Ge
Immature myeloid cells induced by a high-fat diet contribute to liver inflammation.
Hepatology (Baltimore, Md.) 2009;50(5):1412-20.
2009: Deng Zhong-bin; Poliakov Anton; Hardy Robert W; Clements Ronald; Liu Cunren; Liu Yuelong; Wang Jianhua; Xiang Xiaoyu; Zhang Shuangqin; Zhuang Xiaoying; Shah Spandan V; Sun Dongmei; Michalek Sue; Grizzle William E; Garvey Timothy; Mobley Jim; Zhang Huang-Ge
Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance.
Diabetes 2009;58(11):2498-505.
2009: Xiang Xiaoyu; Poliakov Anton; Liu Cunren; Liu Yuelong; Deng Zhong-bin; Wang Jianhua; Cheng Ziqiang; Shah Spandan V; Wang Gui-Jun; Zhang Liming; Grizzle William E; Mobley Jim; Zhang Huang-Ge
Induction of myeloid-derived suppressor cells by tumor exosomes.
International journal of cancer. Journal international du cancer 2009;124(11):2621-33.
2009: Liu Yuelong; Shah Spandan V; Xiang Xiaoyu; Wang Jianhua; Deng Zhong-bin; Liu Cunren; Zhang Liming; Wu Jianming; Edmonds Tara; Jambor Christina; Kappes John C; Zhang Huang-Ge
COP9-associated CSN5 regulates exosomal protein deubiquitination and sorting.
The American journal of pathology 2009;174(4):1415-25.
2008: Wang Gui-Jun; Liu Yuelong; Qin Aijian; Shah Spandan V; Deng Zhong-bin; Xiang Xiaoyu; Cheng Ziqiang; Liu Cunren; Wang Jianhua; Zhang Liming; Grizzle William E; Zhang Huang-Ge
Thymus exosomes-like particles induce regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5242-8.
2007: Grizzle William E; Xu Xin; Zhang Shuangqin; Stockard Cecil R; Liu Cunren; Yu Shaohua; Wang Jianhua; Mountz John D; Zhang Huang-Ge
Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice.
Mechanisms of ageing and development 2007;128(11-12):672-80.
2007: Zhang Huang-Ge; Kim Helen; Liu Cunren; Yu Shaohua; Wang Jianhua; Grizzle William E; Kimberly Robert P; Barnes Stephen
Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity.
Biochimica et biophysica acta 2007;1773(7):1116-23.
2007: Yu Shaohua; Liu Cunren; Su Kaihong; Wang Jianhua; Liu Yuelong; Zhang Liming; Li Chuanyu; Cong Yingzi; Kimberly Robert; Grizzle William E; Falkson Carla; Zhang Huang-Ge
Tumor exosomes inhibit differentiation of bone marrow dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):6867-75.
2007: Liu Cunren; Yu Shaohua; Kappes John; Wang Jianhua; Grizzle William E; Zinn Kurt R; Zhang Huang-Ge
Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host.
Blood 2007;109(10):4336-42.
2007: Benavides Maximo A; Oelschlager Denise K; Zhang Huang-Ge; Stockard Cecil R; Vital-Reyes Victor S; Katkoori Venkat R; Manne Upender; Wang Wenquan; Bland Kirby I; Grizzle William E
Methionine inhibits cellular growth dependent on the p53 status of cells.
American journal of surgery 2007;193(2):274-83.
2007: Ying Wei-Zhong; Zhang Huang-Ge; Sanders Paul W
EGF receptor activity modulates apoptosis induced by inhibition of the proteasome of vascular smooth muscle cells.
Journal of the American Society of Nephrology : JASN 2007;18(1):131-42.
2006: Musani Solomon K; Zhang Huang-Ge; Hsu Hui-Chen; Yi Nengjun; Gorman Bernard S; Allison David B; Mountz John D
Principal component analysis of quantitative trait loci for immune response to adenovirus in mice.
Hereditas 2006;143(2006):189-97.
2006: Wang Jianhua; Li Chuanyu; Liu Yuelong; Mei Wan; Yu Shaohua; Liu Cunren; Zhang Liming; Cao Xu; Kimberly Robert P; Grizzle William; Zhang Huang-Ge
JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha.
The American journal of pathology 2006;169(3):889-902.
2006: Zhang Huang-Ge; Liu Cunren; Su Kaihong; Yu Shaohua; Zhang Liming; Zhang Shuangqin; Wang Jianhua; Cao Xu; Grizzle William; Kimberly Robert P
A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7385-93.
2006: Liu Cunren; Yu Shaohua; Zinn Kurt; Wang Jianhua; Zhang Liming; Jia Yujiang; Kappes John C; Barnes Stephen; Kimberly Robert P; Grizzle William E; Zhang Huang-Ge
Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1375-85.
2005: Yang Xinwen; Wang Jianhua; Liu Cunren; Grizzle William E; Yu Shaohua; Zhang Shuangqin; Barnes Stephen; Koopman William J; Mountz John D; Kimberly Robert P; Zhang Huang-Ge
Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts.
The American journal of pathology 2005;167(3):705-19.
2005: Zhang Huang-Ge; High Katherine A; Wu Qi; Yang PingAr; Schlachterman Alex; Yu Shaohua; Yi Nengjun; Hsu Hui-Chen; Mountz John D
Genetic analysis of the antibody response to AAV2 and factor IX.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(6):866-74.
2005: Hsu Hui-Chen; Li Lina; Zhang Huang-Ge; Mountz John D
Genetic regulation of thymic involution.
Mechanisms of ageing and development 2005;126(1):87-97.
2004: Xu X; Zhang H-G; Liu Z-Y; Wu Q; Yang P-A; Sun S-H; Chen J; Hsu H-C; Mountz J D
Defective clearance of adenovirus in IRF-1 mice associated with defects in NK and T cells but not macrophages.
Scandinavian journal of immunology 2004;60(1-2):89-99.
2004: Zhang Huang-Ge; Wang Jianhua; Yang Xinwen; Hsu Hui-Chen; Mountz John D
Regulation of apoptosis proteins in cancer cells by ubiquitin.
Oncogene 2004;23(11):2009-15.
2004: Zhang Huang-Ge; Hyde Karren; Page Grier P; Brand Jacob P L; Zhou Juling; Yu Shaohua; Allison David B; Hsu Hui-Chen; Mountz John D
Novel tumor necrosis factor alpha-regulated genes in rheumatoid arthritis.
Arthritis and rheumatism 2004;50(2):420-31.
2004: Zhang H-G; Hsu H-C; Yang P-A; Yang X; Wu Q; Liu Z; Yi N; Mountz J D
Identification of multiple genetic loci that regulate adenovirus gene therapy.
Gene therapy 2004;11(1):4-14.
2004: Hoves Sabine; Krause Stefan W; Herfarth Hans; Halbritter Dagmar; Zhang Huang-Ge; Mountz John D; Schölmerich Jürgen; Fleck Martin
Elimination of activated but not resting primary human CD4+ and CD8+ T cells by Fas ligand (FasL/CD95L)-expressing Killer-dendritic cells.
Immunobiology 2004;208(5):463-75.
2003: Liu Zhongyu; Xu Xin; Hsu Hui-Chen; Tousson Albert; Yang Ping-Ar; Wu Qi; Liu Cunren; Yu Shaohua; Zhang Huang-Ge; Mountz John D
CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis.
The Journal of clinical investigation 2003;112(9):1332-41.
2003: Hsu H-C; Zhang H-G; Li L; Yi N; Yang P-A; Wu Q; Zhou J; Sun S; Xu X; Yang X; Lu L; Van Zant G; Williams R W; Allison D B; Mountz J D
Age-related thymic involution in C57BL/6J x DBA/2J recombinant-inbred mice maps to mouse chromosomes 9 and 10.
Genes and immunity 2003;4(6):402-10.
2003: Hoves Sabine; Krause Stefan W; Halbritter Dagmar; Zhang Huang-Ge; Mountz John D; Schölmerich Jürgen; Fleck Martin
Mature but not immature Fas ligand (CD95L)-transduced human monocyte-derived dendritic cells are protected from Fas-mediated apoptosis and can be used as killer APC.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5406-13.
2003: Li L; Hsu H-C; Grizzle W E; Stockard C R; Ho K-J; Lott P; Yang P-A; Zhang H-G; Mountz J D;
Cellular mechanism of thymic involution.
Scandinavian journal of immunology 2003;57(5):410-22.
2003: Zhang Huang-Ge; Grizzle William E
Aging, immunity, and tumor susceptibility.
Immunology and allergy clinics of North America 2003;23(1):83-102, vi.
2002: Zhang Huang-Ge; Xie Jinfu; Dmitriev Igor; Kashentseva Elena; Curiel David T; Hsu Hui-Chen; Mountz John D
Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or production.
Journal of virology 2002;76(23):12023-31.
2002: Grizzle William E; Mountz John D; Yang Ping-Ar; Xu Xin; Sun Sheher; Van Zant Gary E; Williams Robert W; Hsu Hui-Chen; Zhang Huang-Ge
BXD recombinant inbred mice represent a novel T cell-mediated immune response tumor model.
International journal of cancer. Journal international du cancer 2002;101(3):270-9.
2002: Matsuki Y; Zhang H G; Hsu H C; Yang P A; Zhou T; Dodd C H; Cecconi F; Gruss P; Tadakuma T; Mountz J D
Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture.
Scandinavian journal of immunology 2002;56(2):174-84.
2002: Matsuki Y; Li L; Hsu H-C; Yang P A; Zheng R; Edwards C K; Chaudry I H; Zhang H-G; Mountz J D
Soluble Fas gene therapy protects against Fas-mediated apoptosis of hepatocytes but not the lethal effects of Fas-induced TNF-alpha production by Kupffer cells.
Cell death and differentiation 2002;9(6):626-35.
2002: Zhang Huang-Ge; Xie Jinfu; Xu Liang; Yang Pingar; Xu Xin; Sun Sheher; Wang Yongming; Curiel David T; Hsu Hui-Chen; Mountz John D
Hepatic DR5 induces apoptosis and limits adenovirus gene therapy product expression in the liver.
Journal of virology 2002;76(11):5692-700.
2002: Hsu Hui-Chen; Mountz John D; Williams Robert W; Shelton Brent J; Yang Ping-Ar; Matsuki Yasunori; Xu Xin; Dodd Christopher H; Li Lina; Geiger Hartmut; Zhang Huang-Ge; Van Zant Gary
Age-related change in thymic T-cell development is associated with genetic loci on mouse chromosomes 1, 3, and 11.
Mechanisms of ageing and development 2002;123(8):1145-58.
2002: Mountz John D; Zant Gary Van; Allison David B; Zhang Huang-Ge; Hsu Hui-Chen
Beneficial influences of systemic cooperation and sociological behavior on longevity.
Mechanisms of ageing and development 2002;123(8):963-73.
2002: Zhang Huang-Ge; Yang PingAr; Xie Jinfu; Liu Zhongyu; Liu Di; Xiu Liang; Zhou Tong; Wang Yongming; Hsu Hui-Chen; Mountz John D
Depletion of collagen II-reactive T cells and blocking of B cell activation prevents collagen II-induced arthritis in DBA/1j mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4164-72.
2002: Mountz John D; Hsu Hui-Chen; Wu Qi; Liu Hong-Gang; Zhang Huang-Ge; Mountz James M
Molecular imaging: new applications for biochemistry.
Journal of cellular biochemistry. Supplement 2002;39():162-71.
2001: Hsu H C; Shi J; Yang P; Xu X; Dodd C; Matsuki Y; Zhang H G; Mountz J D
Activated CD8(+) T cells from aged mice exhibit decreased activation-induced cell death.
Mechanisms of ageing and development 2001;122(15):1663-84.
2001: Dodd C H; Hsu H C; Chu W J; Yang P; Zhang H G; Mountz J D; Zinn K; Forder J; Josephson L; Weissleder R; Mountz J M; Mountz J D
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles.
Journal of immunological methods 2001;256(1-2):89-105.
2001: Hsu H C; Zhang H G; Song G G; Xie J; Liu D; Yang P A; Fleck M; Wintersberger W; Zhou T; Edwards C K; Mountz J D
Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection.
Arthritis and rheumatism 2001;44(9):2146-59.
2001: Zhang H G; Wang Y; Xie J F; Liang X; Liu D; Yang P; Hsu H C; Ray R B; Mountz J D
Regulation of tumor necrosis factor alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt.
Arthritis and rheumatism 2001;44(7):1555-67.
2001: Mountz J D; Van Zant G E; Zhang H G; Grizzle W E; Ahmed R; Williams R W; Hsu H C
Genetic dissection of age-related changes of immune function in mice.
Scandinavian journal of immunology 2001;54(1-2):10-20.
2001: Zhang H G; Wang Y M; Xie J F; Liang X; Hsu H C; Zhang X; Douglas J; Curiel D T; Mountz J D
Recombinant adenovirus expressing adeno-associated virus cap and rep proteins supports production of high-titer recombinant adeno-associated virus.
Gene therapy 2001;8(9):704-12.
2001: Fleck M; Zhang H G; Kern E R; Hsu H C; Müller-Ladner U; Mountz J D
Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local fasL gene transfer.
Arthritis and rheumatism 2001;44(4):964-73.
2001: Hsu H C; Zhou T; Shi J; Yang P A; Liu D; Zhang H G; Bluethmann H; Mountz J D
Aged mice exhibit in vivo defective peripheral clonal deletion of D(b)/H-Y reactive CD8(+) T cells.
Mechanisms of ageing and development 2001;122(3):305-26.
2001: Hsu H C; Matsuki Y; Zhang H G; Zhou T; Mountz J D
The Fas signaling connection between autoimmunity and embryonic lethality.
Journal of clinical immunology 2001;21(1):1-14.
2001: Hsu H C; Shultz L D; Su X; Shi J; Yang P A; Relyea M J; Zhang H G; Mountz J D
Mutation of the hematopoietic cell phosphatase (Hcph) gene is associated with resistance to gamma-irradiation-induced apoptosis in Src homology protein tyrosine phosphatase (SHP)-1-deficient "motheaten" mutant mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):772-80.
2000: Zhang H G; Xie J; Yang P; Wang Y; Xu L; Liu D; Hsu H C; Zhou T; Edwards C K; Mountz J D
Adeno-associated virus production of soluble tumor necrosis factor receptor neutralizes tumor necrosis factor alpha and reduces arthritis.
Human gene therapy 2000;11(17):2431-42.
2000: Zhang H G; Huang N; Liu D; Bilbao L; Zhang X; Yang P; Zhou T; Curiel D T; Mountz J D
Gene therapy that inhibits nuclear translocation of nuclear factor kappaB results in tumor necrosis factor alpha-induced apoptosis of human synovial fibroblasts.
Arthritis and rheumatism 2000;43(5):1094-105.
2000: Zhang H G; Fleck M; Kern E R; Liu D; Wang Y; Hsu H C; Yang P; Wang Z; Curiel D T; Zhou T; Mountz J D
Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient mice.
The Journal of clinical investigation 2000;105(6):813-21.
1999: Bilbao G; Contreras J L; Zhang H G; Pike M J; Overturf K; Mikheeva G; Krasnykh V; Curiel D T
Adenovirus-mediated gene expression in vivo is enhanced by the antiapoptotic bcl-2 gene.
Journal of virology 1999;73(8):6992-7000.
1999: Zhang H G; Su X; Liu D; Liu W; Yang P; Wang Z; Edwards C K; Bluethmann H; Mountz J D; Zhou T
Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1423-30.
1998: Zhang H G; Liu D; Heike Y; Yang P; Wang Z; Wang X; Curiel D T; Zhou T; Mountz J D
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells.
Nature biotechnology 1998;16(11):1045-9.
1998: Zhang H G; Zhou T; Yang P; Edwards C K; Curiel D T; Mountz J D
Inhibition of tumor necrosis factor alpha decreases inflammation and prolongs adenovirus gene expression in lung and liver.
Human gene therapy 1998;9(13):1875-84.
1998: Zhang H G; Bilbao G; Zhou T; Contreras J L; Gómez-Navarro J; Feng M; Saito I; Mountz J D; Curiel D T
Application of a Fas ligand encoding a recombinant adenovirus vector for prolongation of transgene expression.
Journal of virology 1998;72(3):2483-90.

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Huang-Ge Zhang

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