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Wendy Broom

Research Profile

Chemicals & Drugs

Disorders

Amyotrophic Lateral Sclerosis

Procedures

DNA Mutational Analysis

Physiology

Living Beings

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Publications

TOP 3
Wendy J Broom; Daniel V Johnson; Manuel Garber; Peter M Andersen; Niall Lennon; John Landers; Chad Nusbaum; Carsten Russ; Robert H Brown
DNA sequence analysis of the conserved region around the SOD1 gene locus in recessively inherited ALS.
Wendy J Broom; Matthew Greenway; Ghazaleh Sadri-Vakili; Carsten Russ; Kristen E Auwarter; Kelly E Glajch; Nicolas Dupre; Robert J Swingler; Shaun Purcell; Caroline Hayward; Peter C Sapp; Diane McKenna-Yasek; Paul N Valdmanis; Jean-Pierre Bouchard; Vincent Meininger; Betsy A Hosler; Jonathan D Glass; Meraida Polack; Guy A Rouleau; Jang-Ho Cha; Orla Hardiman; Robert H Brown
50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis.
Wendy J Broom; D V Johnson; K E Auwarter; A John Iafrate; Carsten Russ; A Al-Chalabi; Peter C Sapp; Diane McKenna-Yasek; Peter M Andersen; Robert H Brown
SOD1A4V-mediated ALS: absence of a closely linked modifier gene and origination in Asia.

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All Publications

2009: Wendy J Broom; Daniel V Johnson; Manuel Garber; Peter M Andersen; Niall Lennon; John Landers; Chad Nusbaum; Carsten Russ; Robert H Brown
DNA sequence analysis of the conserved region around the SOD1 gene locus in recessively inherited ALS.
Neuroscience letters 2009;463(1):64-9.
2008: Wendy J Broom; Matthew Greenway; Ghazaleh Sadri-Vakili; Carsten Russ; Kristen E Auwarter; Kelly E Glajch; Nicolas Dupre; Robert J Swingler; Shaun Purcell; Caroline Hayward; Peter C Sapp; Diane McKenna-Yasek; Paul N Valdmanis; Jean-Pierre Bouchard; Vincent Meininger; Betsy A Hosler; Jonathan D Glass; Meraida Polack; Guy A Rouleau; Jang-Ho Cha; Orla Hardiman; Robert H Brown
50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2008;9(4):229-37.
2008: Wendy J Broom; D V Johnson; K E Auwarter; A John Iafrate; Carsten Russ; A Al-Chalabi; Peter C Sapp; Diane McKenna-Yasek; Peter M Andersen; Robert H Brown
SOD1A4V-mediated ALS: absence of a closely linked modifier gene and origination in Asia.
Neuroscience letters 2008;430(3):241-5.
2007: Stephan Niemann; Wendy J Broom; Robert H Brown
Analysis of a genetic defect in the TATA box of the SOD1 gene in a patient with familial amyotrophic lateral sclerosis.
Muscle & nerve 2007;36(5):704-7.
2006: Wendy J Broom; Kristen E Auwarter; Jake Ni; Deborah E Russel; Li-An Yeh; Michele M Maxwell; Marcie A Glicksman; Aleksey G Kazantsev; Robert H Brown
Two approaches to drug discovery in SOD1-mediated ALS.
Journal of biomolecular screening 2006;11(7):729-35.
2006: Wendy J Broom; Ilknur Ay; Piera Pasinelli; Robert H Brown
Inhibition of SOD1 expression by mitomycin C is a non-specific consequence of cellular toxicity.
Neuroscience letters 2006;393(2-3):184-8.
2006: Wendy J Broom; Carsten Russ; Peter C Sapp; Diane McKenna-Yasek; Betsy A Hosler; Peter M Andersen; Robert H Brown
Variants in candidate ALS modifier genes linked to Cu/Zn superoxide dismutase do not explain divergent survival phenotypes.
Neuroscience letters 2006;392(1-2):52-7.