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Qiang Zhang

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Xiaona Tian; Dianrui Zhang; Dandan Zheng; Lejiao Jia; Han Li; Guangpu Liu; Jingyi Shen; Yuemao Shen; Qiang Zhang
Nanosuspension for parenteral delivery of a p-terphenyl derivative: Preparation, characteristics and pharmacokinetic studies.
Cheng-Jun Chen; Qiang Feng; Ling-Yan Gao; Wen-Jie Hou; Xiao-Yan Liu; Wan-Liang Lu; Xiao-Fei Ma; Jian-Cheng Wang; Liang-Ren Zhang; En-Yu Zhao; Zhi-Xia Zhao; Qiang Zhang
Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly(amidoamine) for siRNA delivery.
Bing He; Zengrong Jia; Jiancheng Wang; X Wang; Chao Yu; Lan Yuan; Hua Zhang; Wenbing Dai; Wenwen Du; Yuchen Fan; Xuan Zhang; Qiang Zhang
The transport pathways of polymer nanoparticles in MDCK epithelial cells.

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All Publications

2013: Xiaona Tian; Dianrui Zhang; Dandan Zheng; Lejiao Jia; Han Li; Guangpu Liu; Jingyi Shen; Yuemao Shen; Qiang Zhang
Nanosuspension for parenteral delivery of a p-terphenyl derivative: Preparation, characteristics and pharmacokinetic studies.
Colloids and surfaces. B, Biointerfaces 2013;108():29-33.
2013: Cheng-Jun Chen; Qiang Feng; Ling-Yan Gao; Wen-Jie Hou; Xiao-Yan Liu; Wan-Liang Lu; Xiao-Fei Ma; Jian-Cheng Wang; Liang-Ren Zhang; En-Yu Zhao; Zhi-Xia Zhao; Qiang Zhang
Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly(amidoamine) for siRNA delivery.
Biomaterials 2013;34(21):5303-16.
2013: Bing He; Zengrong Jia; Jiancheng Wang; X Wang; Chao Yu; Lan Yuan; Hua Zhang; Wenbing Dai; Wenwen Du; Yuchen Fan; Xuan Zhang; Qiang Zhang
The transport pathways of polymer nanoparticles in MDCK epithelial cells.
Biomaterials 2013;34(17):4309-26.
2013: Shuqin Yan; Qiang Zhang; Mingzhong Li; Yu Liu; Shenzhou Lu; Jiannan Wang; David L Kaplan
Silk fibroin/chondroitin sulfate/hyaluronic acid ternary scaffolds for dermal tissue reconstruction.
Acta biomaterialia 2013;9(6):6771-82.
2013: Caiyun Li; Guangpu Liu; Jingyi Shen; Xiaona Tian; Dianrui Zhang; Hejian Guo; Leilei Hao; Dandan Zheng; Qiang Zhang
Preparation and characterization of galactosylated bovine serum albumin nanoparticles for liver-targeted delivery of oridonin.
International journal of pharmaceutics 2013;448(1):79-86.
2013: Wenxiang Bi; Yuanfang Guo; Gaoying Sun; Yuping Wei; Jinxiang Wu; Qiang Zhang; Liang Dong
MADD promotes the survival of human lung adenocarcinoma cells by inhibiting apoptosis.
Oncology reports 2013;29(4):1533-9.
2013: Lejiao Jia; Zhenyu Li; Guangpu Liu; Jingyi Shen; Dianrui Zhang; Qiang Zhang; Dandan Zheng; Xiaona Tian
In vitro and in vivo evaluation of paclitaxel-loaded mesoporous silica nanoparticles with three pore sizes.
International journal of pharmaceutics 2013;445(1-2):12-9.
2013: Yuchen Fan; Fengying Fu; Bing He; Jiancheng Wang; Xueqing Wang; Hounan Wu; Lan Yuan; Hua Zhang; Wenbing Dai; Wenwen Du; Xuan Zhang; Qiang Zhang
The reduction of tumor interstitial fluid pressure by liposomal imatinib and its effect on combination therapy with liposomal doxorubicin.
Biomaterials 2013;34(9):2277-88.
2013: Guangpu Liu; Yue Liu; Cunxian Duan; Hejian Guo; Lejiao Jia; Yang Jiao; Caiyun Li; Jingyi Shen; Xiaona Tian; Dianrui Zhang; Qiang Zhang; Dandan Zheng; Hongxiang Lou
In vitro and in vivo evaluation of riccardin D nanosuspensions with different particle size.
Colloids and surfaces. B, Biointerfaces 2013;102():620-6.
2013: Feihu Wang; Dianrui Zhang; Qiang Zhang; Dandan Zheng; Hejian Guo; Shengrong Guo; Leilei Hao; Caiyun Li
Tissue distribution and pharmacokinetics evaluation of DOMC-FA micelles for intravenous delivery of PTX.
Journal of drug targeting 2013;21(2):137-45.
2013: Yuan-Yuan Jiao; Wan-Liang Lu; Xue-Qing Wang; Zhen-Jun Yang; Qiang Zhang
A novel approach to improve the pharmacokinetic properties of 8-chloro-adenosine by the dual combination of lipophilic derivatisation and liposome formulation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2013;48(1-2):249-58.
2013: Yu Duan; Dan Li; Wei Ren; Xin Wang; Ke-Fu Yu; Xuan Zhang; Xin Zhao; Qiang Zhang
Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation.
OncoTargets and therapy 2013;6():189-98.
2013: Xiao-Lei Wang; Qiang Zhang; Cun-Xian Jia; Yu-Yang Li; Li-Yuan Liu; Liang Li
Obesity, diabetes mellitus, and the risk of female breast cancer in Eastern China.
World journal of surgical oncology 2013;11():71.
2013: Li-Min Luo; Ping Song; Ke-Fu Yu; Xuan Zhang; Bing-Xiang Zhao; Xin Zhao; Yang Zhao; Ruo Du; Yu Duan; Yue Huang; Qiang Zhang
Anti-tumor and anti-angiogenic effect of metronomic cyclic NGR-modified liposomes containing paclitaxel.
Biomaterials 2013;34(4):1102-14.
2013: Zhaohui Wang; Hounan Wu; Yang Yu; Lan Yuan; Hua Zhang; Jingrong Cui; Wenbing Dai; Jiancheng Wang; X Wang; Xuan Zhang; Qiang Zhang
A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth.
Biomaterials 2013;34(3):756-64.
2013: Wenwen Du; Yuchen Fan; Bing He; Jiancheng Wang; X Wang; Lan Yuan; Hua Zhang; Xuan Zhang; Nan Zheng; Qiang Zhang
Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery.
Biomaterials 2013;34(3):794-806.
2012: Qiang Zhang; Jiang Zhou; Xiaojie Cui; Sen Lin; Gu Yuan
Convenient method for the synthesis of a flexible cyclic polyamide for selective targeting of c-myb G-quadruplex DNA.
Organic letters 2012;14(24):6126-9.
2012: Lejiao Jia; Zhenyu Li; Guangpu Liu; Yue Liu; Jingyi Shen; Dianrui Zhang; Qiang Zhang; Dandan Zheng; Cunxian Duan; Xiaona Tian
Successfully tailoring the pore size of mesoporous silica nanoparticles: exploitation of delivery systems for poorly water-soluble drugs.
International journal of pharmaceutics 2012;439(1-2):81-91.
2012: Qiang Zhang; Jun-qing Hao; Shan-ying Huang; Yu-ping Wei; Jin-xiang Wu; Liang Dong
[Effect of XPA expression on the chemotherapy sensitivity of A549/DDP cells].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 2012;28(11):1182-4.
2012: Zhaohui Wang; Hounan Wu; Yang Yu; Lan Yuan; Hua Zhang; Jingrong Cui; Wenbing Dai; Jingkai Lu; Jiancheng Wang; X Wang; Xuan Zhang; Qiang Zhang
The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer.
Biomaterials 2012;33(33):8451-60.
2012: Dandan Zheng; Cunxian Duan; Hejian Guo; Lejiao Jia; Caiyun Li; Guangpu Liu; Yue Liu; Feihu Wang; Dianrui Zhang; Qiang Zhang
Galactosylated chitosan nanoparticles for hepatocyte-targeted delivery of oridonin.
International journal of pharmaceutics 2012;436(1-2):379-86.
2012: Xue-Qing Wang; Qiang Zhang
pH-sensitive polymeric nanoparticles to improve oral bioavailability of peptide/protein drugs and poorly water-soluble drugs.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;82(2):219-29.
2012: Xiao-Mei Tao; Jia-bao Wang; Jian-Cheng Wang; Liang-Ren Zhang; Qiang Feng; Shan-yun Gao; Qiang Zhang
Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;82(2):401-9.
2012: Wenbing Dai; Wu Jin; You Wan; Jiancheng Wang; X Wang; Junlin Zhang; Xuan Zhang; Qiang Zhang
Spatiotemporally controlled co-delivery of anti-vasculature agent and cytotoxic drug by octreotide-modified stealth liposomes.
Pharmaceutical research 2012;29(10):2902-11.
2012: Zhi-Xia Zhao; En-Yu Zhao; Cheng-Jun Chen; Qiang Feng; Ling-Yan Gao; Shan-Yun Gao; Wen-Jie Hou; Xiao-Yan Liu; Jian-Cheng Wang; Liang-Ren Zhang; Qiang Zhang
Self-assembly nanomicelles based on cationic mPEG-PLA-b-Polyarginine(R15) triblock copolymer for siRNA delivery.
Biomaterials 2012;33(28):6793-807.
2012: Min Guan; Yang Liu; Xue-Nong Zhang; Yi Zhou; Qiao-Ling Zhu; Yong-Yan Bei; Qiang Zhang
N-trimethyl chitosan nanoparticle-encapsulated lactosyl-norcantharidin for liver cancer therapy with high targeting efficacy.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(7):1172-81.
2012: Wenbing Dai; Jiancheng Wang; Xueqing Wang; Yiguang Wang; Tingyuan Yang; Xuan Zhang; Qiang Zhang
Peptide PHSCNK as an integrin α5β1 antagonist targets stealth liposomes to integrin-overexpressing melanoma.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(7):1152-61.
2012: Jifu Hao; Fugang Wang; Xiaodan Wang; Dianrui Zhang; Yanping Bi; Yunsheng Gao; Xuemei Zhao; Qiang Zhang
Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;47(2):497-505.
2012: Zhaohui Wang; Yang Yu; Haoran Zhang; Hua Zhang; Jie Ma; J Wang; X Wang; Xuan Zhang; Qiang Zhang
LyP-1 modification to enhance delivery of artemisinin or fluorescent probe loaded polymeric micelles to highly metastatic tumor and its lymphatics.
Molecular pharmaceutics 2012;9(9):2646-57.
2012: Suna He; Dong Mei; Xueqing Wang; Hua Zhang; Zheng Cui; Wenbing Dai; Qiang Zhang
A cremophor-free self-microemulsified delivery system for intravenous injection of teniposide: evaluation in vitro and in vivo.
AAPS PharmSciTech 2012;13(3):846-52.
2012: Enyu Zhao; Zhixia Zhao; Chengjun Chen; Qiang Feng; Lingyan Gao; Mingyuan Gao; Wenjie Hou; Jiancheng Wang; Chunhui Yang; Qiang Zhang
Surface engineering of gold nanoparticles for in vitro siRNA delivery.
Nanoscale 2012;4(16):5102-9.
2012: Leilei Hao; Caiyun Li; Yue Liu; Siyang Song; Feihu Wang; Xiaoyong Wang; Qingyan Xu; Dianrui Zhang; Hejian Guo; Dandan Zheng; Qiang Zhang
Studies on the preparation, characterization and pharmacokinetics of Amoitone B nanocrystals.
International journal of pharmaceutics 2012;433(1-2):157-64.
2012: Dandan Zheng; Wenting Dai; Cunxian Duan; Lejiao Jia; Yue Liu; Dianrui Zhang; Qiang Zhang
In vivo studies on the oridonin-loaded nanostructured lipid carriers.
Drug delivery 2012;19(6):286-91.
2012: Qiang Zhang; Huijing Zhao; Yahong Zhao; Mingzhong Li; Shenzhou Lu; Shuqin Yan; Yumin Yang; David L Kaplan
Preparation of uniaxial multichannel silk fibroin scaffolds for guiding primary neurons.
Acta biomaterialia 2012;8(7):2628-38.
2012: Xiangrui Liu; Hannah Scott; Jiabei Sun; Shanshan Wang; Xiaomei Chen; Xuan Zhang; Qiang Zhang
Pharmacokinetics, tissue distribution and anti-tumour efficacy of paclitaxel delivered by polyvinylpyrrolidone solid dispersion.
The Journal of pharmacy and pharmacology 2012;64(6):775-82.
2012: Yun-Huan Jin; Jia-Wei Qi; Ming-Xi Qiao; Qiang Zhang; Jia Zhu; Chan-Juan Hu; Hai-Yang Hu; Da-Wei Chen
pH-sensitive chitosan-derived nanoparticles as doxorubicin carriers for effective anti-tumor activity: preparation and in vitro evaluation.
Colloids and surfaces. B, Biointerfaces 2012;94():184-91.
2012: Nan Zheng; Xuan Zhang; Wenbing Dai; Wenwen Du; Jinming Gao; Liandi Lei; J Wang; X Wang; Hua Zhang; Haoran Zhang; Qiang Zhang
A novel lanreotide-encoded micelle system targets paclitaxel to the tumors with overexpression of somatostatin receptors.
Molecular pharmaceutics 2012;9(5):1175-88.
2012: Yu-Ping Wei; Jin-Xiang Wu; Qiang Zhang; Wen-Xiang Bi; Yuan-Fang Guo; Gao-Ying Sun; Liang Dong
[Expression of MADD in lung adenocarcinoma tissues and its effects on proliferation and apoptosis of lung adenocarcinoma A549 cells].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 2012;28(4):354-7.
2012: Lejiao Jia; Guangpu Liu; Yue Liu; Jingyi Shen; Xiaona Tian; Dianrui Zhang; Cunxian Duan; Dandan Zheng; Qiang Zhang
In vitro and in vivo evaluation of oridonin-loaded long circulating nanostructured lipid carriers.
International journal of biological macromolecules 2012;50(3):523-9.
2012: Peng Zhao; Jinghai Zhang; Qiang Zhang; Yihui Deng; Tongying Jiang; Changshan Sun; Jin Sun; Lihong Wang; Siling Wang
Uniform mesoporous carbon as a carrier for poorly water soluble drug and its cytotoxicity study.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;80(3):535-43.
2012: Yue Liu; Pengcheng Xie; Dianrui Zhang; Qiang Zhang
A mini review of nanosuspensions development.
Journal of drug targeting 2012;20(3):209-23.
2012: Shanshan Zhao; Xuan Zhang; Wenbing Dai; Bing He; Zhonggui He; Jiancheng Wang; Qiang Zhang
Monitoring the transport of polymeric micelles across MDCK cell monolayer and exploring related mechanisms.
Journal of controlled release : official journal of the Controlled Release Society 2012;158(3):413-23.
2012: Yanzhuo Zhang; Qiang Zhang; Xiaoyu Bai; Tongying Jiang; Jiancheng Wang; Siling Wang
Mesoporous silica nanoparticles for increasing the oral bioavailability and permeation of poorly water soluble drugs.
Molecular pharmaceutics 2012;9(3):505-13.
2012: Bing-Xiang Zhao; Yang Zhao; Xuan Zhang; Su Chen; Yue Huang; Lin-Min Luo; Ping Song; Xin Wang; Ke-Fu Yu; Qiang Zhang
The efficiency of tumor-specific pH-responsive peptide-modified polymeric micelles containing paclitaxel.
Biomaterials 2012;33(8):2508-20.
2012: Dan Li; Jie-Si Li; Xing-Huo Li; Wei Ren; Ping Song; Ke Yang; Ke-Fu Yu; Ruo Du; Yu Duan; Xin Hu; Dan Huang; Xiao-Yan Ke; Xuan Zhang; Qiang Zhang
Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings.
International journal of nanomedicine 2012;7():6105-14.
2012: Wei Qu; Jiancheng Wang; Xuan Zhang; Wenbin Dai; Lars Hovgaard; Song Li; Yong Li; Qiang Zhang
A silica-based pH-sensitive nanomatrix system improves the oral absorption and efficacy of incretin hormone glucagon-like peptide-1.
International journal of nanomedicine 2012;7():4983-94.
2012: Jia-lin Wang; Zhao-Hui Wang; Wen-bing Dai; Zhao-ming Guo; Ying Li; Yu-ling Liu; Qiang Zhang
EphA2 targeted doxorubicin stealth liposomes as a therapy system for choroidal neovascularization in rats.
Investigative ophthalmology & visual science 2012;53(11):7348-57.
2012: Cheng-Jun Chen; Ling-Yan Gao; Xiao-Yan Liu; Wan-Liang Lu; Jian-Cheng Wang; En-Yu Zhao; Zhi-Xia Zhao; Shu-Feng Zhou; Qiang Zhang
A comparative study of three ternary complexes prepared in different mixing orders of siRNA/redox-responsive hyperbranched poly (amido amine)/hyaluronic acid.
International journal of nanomedicine 2012;7():3837-49.
2012: Zhi-Gang Yu; Jin Zhang; Qiang Zhang; Jin-Hai Tang; Cui-Zhi Geng; Cun-Xian Jia; Yu-Yang Li; Li-Yuan Liu; Zhong-Bing Ma
The prevalence and correlates of breast cancer among women in Eastern China.
PloS one 2012;7(6):e37784.
2012: Yong-yan Bei; Wei-liang Chen; Xiao-yan Chen; Zong-lin Gu; Yang Liu; Lin-seng Shi; Qin Wang; Wen-juan Wang; Kong-lang Xing; Jing-yu Xu; Xue-nong Zhang; Ai-jun Zhu; Qiang Zhang
Novel norcantharidin-loaded liver targeting chitosan nanoparticles to enhance intestinal absorption.
International journal of nanomedicine 2012;7():1819-27.
2012: Xin-Yuan Ding; Zong-Lin Gu; Cheng-Jiao Hong; Yang Liu; Lin-Seng Shi; Kong-Lang Xing; Xue-Nong Zhang; Ai-Jun Zhu; Wei-Liang Chen; Qiang Zhang
Pharmacokinetics, tissue distribution, and metabolites of a polyvinylpyrrolidone-coated norcantharidin chitosan nanoparticle formulation in rats and mice, using LC-MS/MS.
International journal of nanomedicine 2012;7():1723-35.
2012: Qiang Zhang; Li-yuan Liu; Kun Mu; Fei Wang; Zhi-gang Yu
The changes in female physical and childbearing characteristics in China and potential association with risk of breast cancer.
BMC public health 2012;12():368.
2012: Min Guan; Yang Liu; Yong-Yan Bei; Zong-Lin Gu; Xue-Nong Zhang; Qiao-Ling Zhu; Qiang Zhang
Uptake and transport of a novel anticancer drug-delivery system: lactosyl-norcantharidin-associated N-trimethyl chitosan nanoparticles across intestinal Caco-2 cell monolayers.
International journal of nanomedicine 2012;7():1921-30.
2012: Shanshan Zhao; Xuan Zhang; Zhonggui He; Jiancheng Wang; Lan Yuan; Qiang Zhang
A novel and facile approach to imaging nanoparticles transport across Transwell filter grown cell monolayer in real-time and in situ under confocal laser scanning microscopy.
Biological & pharmaceutical bulletin 2012;35(3):335-45.
2012: Feihu Wang; Dianrui Zhang; Qiang Zhang; Dandan Zheng; Yuxuan Chen; Cunxian Duan; Leilei Hao; Lejiao Jia; Yue Liu; Guangpu Liu
Folate-mediated targeted and intracellular delivery of paclitaxel using a novel deoxycholic acid-O-carboxymethylated chitosan-folic acid micelles.
International journal of nanomedicine 2012;7():325-37.
2012: Yue Liu; Feihu Wang; Pengcheng Xie; Dianrui Zhang; Cunxian Duan; Leilei Hao; Lejiao Jia; Guangpu Liu; Xueshun Zhang; Dandan Zheng; Qiang Zhang
Studies on pharmacokinetics and tissue distribution of bifendate nanosuspensions for intravenous delivery.
Journal of microencapsulation 2012;29(2):194-203.
2012: Yang Zhang; Xuan Zhang; Jiancheng Wang; Xueqing Wang; Hua Zhang; Qiang Zhang
The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles.
Biomaterials 2012;33(2):679-91.
2011: Feihu Wang; Dianrui Zhang; Qiang Zhang; Dandan Zheng; Yuxuan Chen; Cunxian Duan; Leilei Hao; Lejiao Jia; Guangpu Liu; Yue Liu
Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance.
Biomaterials 2011;32(35):9444-56.
2011: Gu Yuan; Qiang Zhang; Jiang Zhou; Huihui Li
Mass spectrometry of G-quadruplex DNA: formation, recognition, property, conversion, and conformation.
Mass spectrometry reviews 2011;30(6):1121-42.
2011: Xue-Qing Wang; Jie-ming Fan; Zeng-rong Jia; Ya-ou Liu; Bo Zhao; Qiang Zhang
Bioavailability and pharmacokinetics of sorafenib suspension, nanoparticles and nanomatrix for oral administration to rat.
International journal of pharmaceutics 2011;419(1-2):339-46.
2011: Haiyan Lou; Xinbing Wei; Dianrui Zhang; Lei Gao; Ying Li; Xiumei Zhang; Zhen Zhang; Dandan Zheng; Qiang Zhang
Oridonin nanosuspension enhances anti-tumor efficacy in SMMC-7721 cells and H22 tumor bearing mice.
Colloids and surfaces. B, Biointerfaces 2011;87(2):319-25.
2011: Zengrong Jia; Ping Lin; Jiancheng Wang; Xueqing Wang; Yu Xiang; Xuan Zhang; Qiang Zhang
A novel nanomatrix system consisted of colloidal silica and pH-sensitive polymethylacrylate improves the oral bioavailability of fenofibrate.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011;79(1):126-34.
2011: Hua Zhang; Qiang Zhang; Christin P Hollis; Tonglei Li
Preparation and antitumor study of camptothecin nanocrystals.
International journal of pharmaceutics 2011;415(1-2):293-300.
2011: Dandan Zheng; Yancai Wang; Dianrui Zhang; Zhaoping Liu; Cunxian Duan; Lejiao Jia; Feihu Wang; Yue Liu; Guangpu Liu; Leilei Hao; Qiang Zhang
In vitro antitumor activity of silybin nanosuspension in PC-3 cells.
Cancer letters 2011;307(2):158-64.
2011: Hong-an Liu; Yu-ling Liu; Zhi-zhong Ma; Jian-Cheng Wang; Qiang Zhang
A lipid nanoparticle system improves siRNA efficacy in RPE cells and a laser-induced murine CNV model.
Investigative ophthalmology & visual science 2011;52(7):4789-94.
2011: Bo-Jun Zhao; Xi-Yu Ke; Yue Huang; Xiao-Mei Chen; Xin Zhao; Bing-Xiang Zhao; Wan-Liang Lu; Jin-Ning Lou; Xuan Zhang; Qiang Zhang
The antiangiogenic efficacy of NGR-modified PEG-DSPE micelles containing paclitaxel (NGR-M-PTX) for the treatment of glioma in rats.
Journal of drug targeting 2011;19(5):382-90.
2011: Cunxian Duan; Dianrui Zhang; Feihu Wang; Dandan Zheng; Lejiao Jia; Feifei Feng; Yue Liu; Yancai Wang; Keli Tian; Fengshan Wang; Qiang Zhang
Chitosan-g-poly(N-isopropylacrylamide) based nanogels for tumor extracellular targeting.
International journal of pharmaceutics 2011;409(1-2):252-9.
2011: Yuan Zhang; X Wang; J Wang; Xuan Zhang; Qiang Zhang
Octreotide-modified polymeric micelles as potential carriers for targeted docetaxel delivery to somatostatin receptor overexpressing tumor cells.
Pharmaceutical research 2011;28(5):1167-78.
2011: Chunxia Zhao; Xiufang Wu; Qiang Zhang; Shuqin Yan; Mingzhong Li
Enzymatic degradation of Antheraea pernyi silk fibroin 3D scaffolds and fibers.
International journal of biological macromolecules 2011;48(2):249-55.
2011: Yiguang Wang; Tingyuan Yang; X Wang; Wenbing Dai; Jiancheng Wang; Xuan Zhang; Zaiquan Li; Qiang Zhang
Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system.
Journal of controlled release : official journal of the Controlled Release Society 2011;149(3):299-306.
2011: ChuanYun Dai; Ya Fu; Biao Li; YiGuang Wang; Xuan Zhang; JianCheng Wang; Qiang Zhang
Linkage with cathepsin B-sensitive dipeptide promotes the in vitro and in vivo anticancer activity of PEGylated tumor necrosis factor-alpha (TNF-α) against murine fibrosarcoma.
Science China. Life sciences 2011;54(2):128-38.
2011: Qiang Zhang; Lihua J Zhu; Scott Lonning; Vidit Sharma; Beverly A Teicher; Ximing J Yang; Nengwang Yu; Charles Brendler; William J Catalona; Lin Chen; Yinglu Guo; Jay Harper; Brian T Helfand; Thomas L Jang; Borko Javonovic; James Kozlowski; Timothy Michael Kuzel; Chung Lee
TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence.
PloS one 2011;6(9):e25168.
2011: Xinru Li; Yan Liu; Xiaoning Wang; Chao Fan; Yating Fan; Yanhui Zhang; Yanxia Zhou; Qiang Zhang
Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol.
Nanoscale research letters 2011;6(1):275.
2011: Jin-Yang Zhang; Zheng Cui; Bing He; Wei Qu; Jian-Cheng Wang; Yi-bo Wang; Hua Zhang; Qiang Zhang
Preparation of the albumin nanoparticle system loaded with both paclitaxel and sorafenib and its evaluation in vitro and in vivo.
Journal of microencapsulation 2011;28(6):528-36.
2011: Feifei Feng; Dandan Zheng; Dianrui Zhang; Cunxian Duan; Yancai Wang; Lejiao Jia; Feihu Wang; Yue Liu; Qun Gao; Qiang Zhang
Preparation, characterization and biodistribution of nanostructured lipid carriers for parenteral delivery of bifendate.
Journal of microencapsulation 2011;28(4):280-5.
2011: Chun-Hui Zhang; Bing-Xiang Zhao; Yue Huang; Ying Wang; Xi-Yu Ke; Bo-Jun Zhao; Xuan Zhang; Qiang Zhang
A novel domperidone hydrogel: preparation, characterization, pharmacokinetic, and pharmacodynamic properties.
Journal of drug delivery 2011;2011():841054.
2011: Ying Wang; Ke-Chun Wu; Bing-Xiang Zhao; Xin Zhao; Xin Wang; Su Chen; Shu-Fang Nie; Wei-San Pan; Xuan Zhang; Qiang Zhang
A novel paclitaxel microemulsion containing a reduced amount of Cremophor EL: pharmacokinetics, biodistribution, and in vivo antitumor efficacy and safety.
Journal of biomedicine & biotechnology 2011;2011():854872.
2011: Yanqin Li; Qiang Zhang; Xiaolei Yin; Weifeng Yang; Yuanyuan Du; Pingping Hou; Jian Ge; Chun Liu; Weiqi Zhang; Xu Zhang; Yetao Wu; Honggang Li; Kang Liu; Chen Wu; Zhihua Song; Yang Zhao; Yan Shi; Hongkui Deng
Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.
Cell research 2011;21(1):196-204.
2011: Jie Yin; Zaiquan Li; Tingyuan Yang; Jiancheng Wang; Xuan Zhang; Qiang Zhang
Cyclic RGDyK conjugation facilitates intracellular drug delivery of polymeric micelles to integrin-overexpressing tumor cells and neovasculature.
Journal of drug targeting 2011;19(1):25-36.
2010: Nengwang Yu; James M Kozlowski; Irwin I Park; Lin Chen; Qiang Zhang; Danfeng Xu; Jennifer A Doll; Susan E Crawford; Charles B Brendler; Chung Lee
Overexpression of transforming growth factor β1 in malignant prostate cells is partly caused by a runaway of TGF-β1 auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-β type I receptor.
Urology 2010;76(6):1519.e8-13.
2010: Juan Jiang; Shi-Jin Yang; Jian-Cheng Wang; Li-Juan Yang; Zhen-Zhong Xu; Ting Yang; Xiao-Yan Liu; Qiang Zhang
Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010;76(2):170-8.
2010: Yiguang Wang; Tingyuan Yang; X Wang; Jiancheng Wang; Xuan Zhang; Qiang Zhang
Targeted polymeric micelle system for delivery of combretastatin A4 to tumor vasculature in vitro.
Pharmaceutical research 2010;27(9):1861-8.
2010: Junlin Zhang; Wu Jin; Xueqing Wang; J Wang; Xuan Zhang; Qiang Zhang
A novel octreotide modified lipid vesicle improved the anticancer efficacy of doxorubicin in somatostatin receptor 2 positive tumor models.
Molecular pharmaceutics 2010;7(4):1159-68.
2010: Xiao-Yan Ke; Bo-Jun Zhao; Xin Zhao; Ying Wang; Yue Huang; Xiao-Mei Chen; Bing-Xiang Zhao; Shan-Shan Zhao; Xuan Zhang; Qiang Zhang
The therapeutic efficacy of conjugated linoleic acid - paclitaxel on glioma in the rat.
Biomaterials 2010;31(22):5855-64.
2010: Yue Huang; Xiao-Mei Chen; Bing-Xiang Zhao; Xi-Yu Ke; Bo-Jun Zhao; Xin Zhao; Ying Wang; Xuan Zhang; Qiang Zhang
Antiangiogenic activity of sterically stabilized liposomes containing paclitaxel (SSL-PTX): in vitro and in vivo.
AAPS PharmSciTech 2010;11(2):752-9.
2010: Wenbing Dai; Tingyuan Yang; Xueqing Wang; Jiancheng Wang; Xuan Zhang; Qiang Zhang
PHSCNK-Modified and doxorubicin-loaded liposomes as a dual targeting system to integrin-overexpressing tumor neovasculature and tumor cells.
Journal of drug targeting 2010;18(4):254-63.
2010: Qin Wang; Liang Zhang; Wei Hu; Zhan-Hong Hu; Yong-Yan Bei; Jing-Yu Xu; Wen-Juan Wang; Xue-Nong Zhang; Qiang Zhang
Norcantharidin-associated galactosylated chitosan nanoparticles for hepatocyte-targeted delivery.
Nanomedicine : nanotechnology, biology, and medicine 2010;6(2):371-81.
2010: J Wu; H Yang; Z Qiu; Qiang Zhang; T Ding; D Geng
Effect of combined treatment with methylprednisolone and Nogo-A monoclonal antibody after rat spinal cord injury.
The Journal of international medical research 2010;38(2):570-82.
2010: Yi-Fei Zhang; Jian-Cheng Wang; Dong-Yan Bian; Xuan Zhang; Qiang Zhang
Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A-4 and doxorubicin for tumor therapy: in vitro and in vivo studies.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010;74(3):467-73.
2010: Xue Ying; He Wen; Wan-Liang Lu; Ju Du; Jia Guo; Wei Tian; Ying Men; Yan Zhang; Ruo-Jing Li; Ting-Yuan Yang; De-Wei Shang; Jin-Ning Lou; Liang-Ren Zhang; Qiang Zhang
Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(2):183-92.
2010: Fenghua Xu; Guiyang Liu; Qiang Zhang; Ronald A Siegel
A comparative study on two phenylboronic acid based glucose-sensitive hydrogels.
Frontiers in bioscience (Elite edition) 2010;2():657-67.
2010: Le-Jiao Jia; Zhen-Yu Li; Yan-Cai Wang; Dian-Rui Zhang; Wen-Ting Dai; Cun-Xian Duan; Fei-Fei Feng; Qiang Zhang
Preparation and characterization of silybin-loaded nanostructured lipid carriers.
Drug delivery 2010;17(1):11-8.
2009: Irwin I Park; Qiang Zhang; Victoria Liu; James M Kozlowski; Ju Zhang; Chung Lee
17Beta-estradiol at low concentrations acts through distinct pathways in normal versus benign prostatic hyperplasia-derived prostate stromal cells.
Endocrinology 2009;150(10):4594-605.
2009: X Wang; Yiguang Wang; X Chen; Jiancheng Wang; Xuan Zhang; Qiang Zhang
NGR-modified micelles enhance their interaction with CD13-overexpressing tumor and endothelial cells.
Journal of controlled release : official journal of the Controlled Release Society 2009;139(1):56-62.
2009: Yiguang Wang; Xun Wang; Yifei Zhang; Shijin Yang; Jiancheng Wang; Xuan Zhang; Qiang Zhang
RGD-modified polymeric micelles as potential carriers for targeted delivery to integrin-overexpressing tumor vasculature and tumor cells.
Journal of drug targeting 2009;17(6):459-67.
2009: Li Ma; Yu-Ling Liu; Zhi-zhong Ma; Hong-Liang Dou; Jun-Hui Xu; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
Targeted treatment of choroidal neovascularization using integrin-mediated sterically stabilized liposomes loaded with combretastatin A4.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2009;25(3):195-200.
2009: Qiang Zhang; Brian T Helfand; Thomas L Jang; Lihua J Zhu; Lin Chen; Ximing J Yang; James Kozlowski; Norm Smith; Shilajit D Kundu; Guang-Yu Yang; Adekunle A Raji; Borko Javonovic; Michael Pins; Paul Lindholm; Yinglu Guo; William J Catalona; Chung Lee
Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(10):3557-67.
2009: Ju Du; Wan-Liang Lu; Xue Ying; Yang Liu; Ping Du; Wei Tian; Ying Men; Jia Guo; Yan Zhang; Ruo-Jing Li; Jia Zhou; Jin-Ning Lou; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumor-bearing animals.
Molecular pharmaceutics 2009;6(3):905-17.
2009: Yang Yang; JianCheng Wang; Xuan Zhang; WangLiang Lu; Qiang Zhang
A novel mixed micelle gel with thermo-sensitive property for the local delivery of docetaxel.
Journal of controlled release : official journal of the Controlled Release Society 2009;135(2):175-82.
2008: Yi Sun; Jiancheng Wang; Xuan Zhang; Zhijun Zhang; Yan Zheng; Dawei Chen; Qiang Zhang
Synchronic release of two hormonal contraceptives for about one month from the PLGA microspheres: in vitro and in vivo studies.
Journal of controlled release : official journal of the Controlled Release Society 2008;129(3):192-9.
2008: Gong-Wen Liang; Wan-Liang Lu; Jin-Wei Wu; Ji-Hui Zhao; Hai-Yan Hong; Chuan Long; Ting Li; Yu-Teng Zhang; Hua Zhang; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
Enhanced therapeutic effects on the multi-drug resistant human leukemia cells in vitro and xenograft in mice using the stealthy liposomal vincristine plus quinacrine.
Fundamental & clinical pharmacology 2008;22(4):429-37.
2008: Juan-Li Lu; Jian-Cheng Wang; Shu-Xin Zhao; Xiao-Yan Liu; Hui Zhao; Xuan Zhang; Shu-Feng Zhou; Qiang Zhang
Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(3):899-907.
2008: Mao-Bo Cheng; Jian-Cheng Wang; Yu-Hua Li; Xiao-Yan Liu; Xuan Zhang; Da-Wei Chen; Shu-Feng Zhou; Qiang Zhang
Characterization of water-in-oil microemulsion for oral delivery of earthworm fibrinolytic enzyme.
Journal of controlled release : official journal of the Controlled Release Society 2008;129(1):41-8.
2008: Yang Liu; Wan-Liang Lu; Jia Guo; Ju Du; Ting Li; Jin-Wei Wu; Gui-Ling Wang; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
A potential target associated with both cancer and cancer stem cells: a combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2008;129(1):18-25.
2008: Kent Perry; Larry Wong; Victoria Liu; Irwin Park; Qiang Zhang; Varun Rejen; Xuemei Huang; Norm D Smith; Borko Jovanovic; Scott Lonning; Beverly A Teicher; Chung Lee
Treatment of transforming growth factor-beta-insensitive mouse Renca tumor by transforming growth factor-beta elimination.
Urology 2008;72(1):225-9.
2008: Meng Meng; Yu Liu; Yi-Bo Wang; Jian-Cheng Wang; Hua Zhang; Xue-Qing Wang; Xuan Zhang; Wan-Liang Lu; Qiang Zhang
Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2008;128(2):113-9.
2008: Xiang-Rui Liu; Ke-Chun Wu; Yue Huang; Jia-Bei Sun; Xi-Yu Ke; Jian-Cheng Wang; Wan-Liang Lu; Xuan Zhang; Qiang Zhang
In vitro and in vivo studies on plasma-to-blood ratio of paclitaxel in human, rabbit and rat blood fractions.
Biological & pharmaceutical bulletin 2008;31(6):1215-20.
2008: Xue-Qing Wang; Jun-dong Dai; Hua Zhang; Xuan Zhang; Jian-Cheng Wang; Qiang Zhang
Absorption mechanism of cyclosporine A loaded pH-sensitive nanoparticles in rats.
Journal of nanoscience and nanotechnology 2008;8(5):2422-31.
2008: Rong-Rong Guo; Yang Liu; Wan-Liang Lu; Ji-Hui Zhao; Xue-Qing Wang; Hua Zhang; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
A recombinant peptide, hirudin, potentiates the inhibitory effects of stealthy liposomal vinblastine on the growth and metastasis of melanoma.
Biological & pharmaceutical bulletin 2008;31(4):696-702.
2008: W Xiao; Qiang Zhang; Geoffrey M Habermacher; X Yang; A-Y Zhang; X Cai; J Hahn; J Liu; Michael Pins; Lynn Doglio; R Dhir; J Gingrich; Z Wang
U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia.
Oncogene 2008;27(11):1536-44.
2008: Shilajit D Kundu; Chung Lee; Benjamin K Billips; Geoffrey M Habermacher; Qiang Zhang; Victoria C Liu; Larry Y Wong; David J Klumpp; Praveen Thumbikat
The toll-like receptor pathway: a novel mechanism of infection-induced carcinogenesis of prostate epithelial cells.
The Prostate 2008;68(2):223-9.
2008: Shuang-Qing Zhang; Xu-Ying Zhong; Guo-Hua Chen; Wan-Liang Lu; Qiang Zhang
The anti-diabetic effects and pharmacokinetic profiles of bis(maltolato)oxovanadium in non-diabetic and diabetic rats.
The Journal of pharmacy and pharmacology 2008;60(1):99-105.
2007: Yu-jie Zhang; Qiang Zhang; Jie Yang; Ming-jie Sun; Xiao-liang Wang; Ming-xia Chen; Qi Wang; Hao Jiang
[Promoting mechanism of enhancers and transport pathway of large hydrophilic molecular across nasal epithelium studied by ESR and CLSM technologies].
Yao xue xue bao = Acta pharmaceutica Sinica 2007;42(11):1195-200.
2007: Ji-Hui Zhao; Ji-Hua Fu; Shu-Ming Wang; Chang-Hai Su; Ying Shan; Shu-Jia Kong; Yuan Wang; Wan-Liang Lu; Hua Zhang; Shuang Zhang; Lin Li; En-Hong Zhang; li wang; Qiu-Ling Pei; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
A novel transdermal patch incorporating isosorbide dinitrate with bisoprolol: in vitro and in vivo characterization.
International journal of pharmaceutics 2007;337(1-2):88-101.
2007: Xue-nong Zhang; J Xu; Li-Hua Tang; J Gong; Xue-Ying Yan; Qiang Zhang
Influence on intestinal mucous permeation of paclitaxel of absorption enhancers and dosage forms based on electron spin resonance spectroscopy.
Die Pharmazie 2007;62(5):368-71.
2007: Victoria C Liu; Larry Y Wong; Thomas Jang; Ali H Shah; Irwin Park; Ximing Yang; Qiang Zhang; Scott Lonning; Beverly A Teicher; Chung Lee
Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2883-92.
2007: Yu Liu; Wan-Liang Lu; Jian-Cheng Wang; Xuan Zhang; Hua Zhang; Xue-Qing Wang; Tian-Yan Zhou; Qiang Zhang
Controlled delivery of recombinant hirudin based on thermo-sensitive Pluronic F127 hydrogel for subcutaneous administration: In vitro and in vivo characterization.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(3):387-95.
2007: Ming-Guang Li; Wan-Liang Lu; Jian-Cheng Wang; Xuan Zhang; Xue-Qing Wang; Ai-ping Zheng; Qiang Zhang
Distribution, transition, adhesion and release of insulin loaded nanoparticles in the gut of rats.
International journal of pharmaceutics 2007;329(1-2):182-91.
2007: Shuang-Qing Zhang; Guo-Hua Chen; Wan-Liang Lu; Qiang Zhang
Effects on the bones of vanadyl acetylacetonate by oral administration: a comparison study in diabetic rats.
Journal of bone and mineral metabolism 2007;25(5):293-301.
2006: Yu-jie Zhang; Jian-mei Wu; Qiang Zhang; Ming-xia Chen; Wan-jing Sun
[Degradation of recombinant hirudin-2 in nasal mucosa of rabbits in vitro].
Yao xue xue bao = Acta pharmaceutica Sinica 2006;41(11):1099-103.
2006: Ting Li; Wan-Liang Lu; Hai-Yan Hong; Yan-Sheng Yao; Pu Han; Zhong-Kun Li; Gui-Ling Wang; Yi Cao; Xiang-Rui Liu; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
Pharmacokinetics and anti-asthmatic potential of non-parenterally administered recombinant human interleukin-1 receptor antagonist in animal models.
Journal of pharmacological sciences 2006;102(3):321-30.
2006: Yu-Hua Li; Mo Zhang; Jian-Cheng Wang; Shu Zhang; Jian-Rong Liu; Qiang Zhang
[Effects of absorption enhancers on intestinal absorption of lumbrokinase].
Yao xue xue bao = Acta pharmaceutica Sinica 2006;41(10):939-44.
2006: Xue-Qing Wang; Jia Huang; Jun-dong Dai; Tao Zhang; Wan-liang Lü; Hua Zhang; Xuan Zhang; Jian-cheng Wang; Qiang Zhang
Long-term studies on the stability and oral bioavailability of cyclosporine A nanoparticle colloid.
International journal of pharmaceutics 2006;322(1-2):146-53.
2006: Ai-ping Zheng; Jian-Cheng Wang; Wan-Liang Lu; Xuan Zhang; Hua Zhang; Xue-Qing Wang; Qiang Zhang
Thymopentin-loaded pH-sensitive chitosan nanoparticles for oral administration: preparation, characterization, and pharmacodynamics.
Journal of nanoscience and nanotechnology 2006;6(9-10):2936-44.
2006: Ming-Guang Li; Wan-Liang Lu; Jian-Cheng Wang; Xuan Zhang; Hua Zhang; Xue-Qing Wang; Cui-Shuan Wu; Qiang Zhang
Preparation and characterization of insulin nanoparticles employing chitosan and poly(methylmethacrylate/methylmethacrylic acid) copolymer.
Journal of nanoscience and nanotechnology 2006;6(9-10):2874-86.
2006: Yuan He; Yu Liu; Yu Liu; Jiancheng Wang; Xuan Zhang; Wanliang Lu; Zhizhong Ma; Xiuan Zhu; Qiang Zhang
Cyclosporine-loaded microspheres for treatment of uveitis: in vitro characterization and in vivo pharmacokinetic study.
Investigative ophthalmology & visual science 2006;47(9):3983-8.
2006: Yang Liu; Wan-liang Lü; Qiang Zhang
[Recent advances in liposomes and nanoparticles as drug carriers for drug delivery].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 2006;28(4):583-9.
2006: Qiang Zhang; Wei Zhou; Shilajit Kundu; Thomas L Jang; Ximing Yang; Michael Pins; Norm Smith; Borko Jovanovic; Dian-qi Xin; Lili Liang; Yinglu Guo; Chung Lee
The leader sequence triggers and enhances several functions of clusterin and is instrumental in the progression of human prostate cancer in vivo and in vitro.
BJU international 2006;98(2):452-60.
2006: Qiang Zhang; Ximing J Yang; Shilajit D Kundu; Michael Pins; Borko Javonovic; Robert Meyer; Seong-Jin Kim; Norman M Greenberg; Timothy Kuzel; Richard Meagher; Yinglu Guo; Chung Lee
Blockade of transforming growth factor-{beta} signaling in tumor-reactive CD8(+) T cells activates the antitumor immune response cycle.
Molecular cancer therapeutics 2006;5(7):1733-43.
2006: X Li; Wan-Liang Lu; Gong-Wen Liang; Guo-Rui Ruan; Hai-Yan Hong; C Long; Y T Zhang; Yang Liu; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
Effect of stealthy liposomal topotecan plus amlodipine on the multidrug-resistant leukaemia cells in vitro and xenograft in mice.
European journal of clinical investigation 2006;36(6):409-18.
2006: Xing Li; Guo-Rui Ruan; Wan-Liang Lu; Hai-Yan Hong; Gong-Wen Liang; Yu-Teng Zhang; Yang Liu; Chuan Long; Xi Ma; Lan Yuan; Jian-Cheng Wang; Xuan Zhang; Qiang Zhang
A novel stealth liposomal topotecan with amlodipine: apoptotic effect is associated with deletion of intracellular Ca2+ by amlodipine thus leading to an enhanced antitumor activity in leukemia.
Journal of controlled release : official journal of the Controlled Release Society 2006;112(2):186-98.
2006: Yuan He; Jian-Cheng Wang; Yu-Ling Liu; Zhi-zhong Ma; Xiu-an Zhu; Qiang Zhang
Therapeutic and toxicological evaluations of cyclosporine a microspheres as a treatment vehicle for uveitis in rabbits.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2006;22(2):121-31.
2006: Jing Wang; Wan-Liang Lu; Gong-Wen Liang; Ke-Chun Wu; Chun-Guang Zhang; Xuan Zhang; Jian-Cheng Wang; Hua Zhang; Xue-Qing Wang; Qiang Zhang
Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague-Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers.
Peptides 2006;27(4):826-35.
2006: Yu-jie Zhang; Qiang Zhang; Jun-ling Hou; Xiao-liang Wang; Ming-xia Chen
[The pharmacokinetics and pharmacodynamics of recombinant hirudin-2 nasal spray].
Yao xue xue bao = Acta pharmaceutica Sinica 2006;41(3):268-71.
2006: Xue-nong Zhang; Li-Hua Tang; Jin-Hong Gong; Xue-Ying Yan; Qiang Zhang
An alternative paclitaxel self-emulsifying microemulsion formulation: preparation, pharmacokinetic profile, and hypersensitivity evaluation.
PDA journal of pharmaceutical science and technology / PDA 2006;60(2):89-94.
2006: Qiang Zhang; Thomas L Jang; Ximing Yang; Irwin Park; Robert E Meyer; Shilajit Kundu; Michael Pins; Borko Javonovic; Timothy Kuzel; Seong-Jin Kim; Luk Van Parijs; Norm Smith; Larry Wong; Norman M Greenberg; Yinglu Guo; Chung Lee
Infiltration of tumor-reactive transforming growth factor-beta insensitive CD8+ T cells into the tumor parenchyma is associated with apoptosis and rejection of tumor cells.
The Prostate 2006;66(3):235-47.
2005: Xiao-Bing Xiong; Yue Huang; Wan-liang Lü; Xuan Zhang; Hua Zhang; Qiang Zhang
[Preparation of doxorubicin-loaded stealth liposomes modified with RGD mimetic and cellular association in vitro].
Yao xue xue bao = Acta pharmaceutica Sinica 2005;40(12):1085-90.
2005: Chun-Ying Cui; Wan-Liang Lu; Lan Xiao; Shuang-Qing Zhang; Yan-Bei Huang; Sheng-Lin Li; Rui-Juan Zhang; Gui-Ling Wang; Xuan Zhang; Qiang Zhang
Sublingual delivery of insulin: effects of enhancers on the mucosal lipid fluidity and protein conformation, transport, and in vivo hypoglycemic activity.
Biological & pharmaceutical bulletin 2005;28(12):2279-88.
2005: Yu-jie Zhang; Chang-hua Ma; Wan-Liang Lu; Xuan Zhang; Xiao-liang Wang; Jian-ning Sun; Qiang Zhang
Permeation-enhancing effects of chitosan formulations on recombinant hirudin-2 by nasal delivery in vitro and in vivo.
Acta pharmacologica Sinica 2005;26(11):1402-8.
2005: Xiao-Bing Xiong; Yue Huang; Wan-Liang Lu; Xuan Zhang; Hua Zhang; Tsuneji Nagai; Qiang Zhang
Enhanced intracellular delivery and improved antitumor efficacy of doxorubicin by sterically stabilized liposomes modified with a synthetic RGD mimetic.
Journal of controlled release : official journal of the Controlled Release Society 2005;107(2):262-75.
2005: Chao Li; Yu-liang Li; Zhong-gao Wang; Qiang Zhang; Yong-quan Gu; Jie-fang Bian
[Application of endovascular thoracic branched aortic stent-grafts in the treatment of aortic arch dissection].
Zhonghua wai ke za zhi [Chinese journal of surgery] 2005;43(18):1184-6.
2005: Xue-nong Zhang; Li-Hua Tang; Xue-Ying Yan; Qiang Zhang
[The influence of absorption enhancer and preparation of paclitaxel on its intestinal mucous membrane permeation detected by enhancement by using electron spin resonance technique].
Yao xue xue bao = Acta pharmaceutica Sinica 2005;40(9):861-4.
2005: Qiang Zhang; Jonathan N Rubenstein; Thomas L Jang; Michael Pins; Borko Javonovic; Ximing Yang; Seong-Jin Kim; Irwin Park; Chung Lee
Insensitivity to transforming growth factor-beta results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP).
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2390-9.
2005: Xiao-Bing Xiong; Yue Huang; Wan-Liang Lu; Xuan Zhang; Hua Zhang; Tsuneji Nagai; Qiang Zhang
Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved antitumor efficacy: in vitro and in vivo.
Journal of pharmaceutical sciences 2005;94(8):1782-93.
2005: Yu-Jie Zhang; Jun-Ling Hou; Chang-hua Ma; Xiao-Liang Wang; Ming-xia Chen; Qiang Zhang
[Studies on the nasal epithelium toxicity of adjuvants and recombination hirudin (rHV2) nasal spary].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 2005;30(11):821-4.
2005: Xiao-Bing Xiong; Yue Huang; Wan-Liang Lu; Hua Zhang; Xuan Zhang; Qiang Zhang
Enhanced intracellular uptake of sterically stabilized liposomal Doxorubicin in vitro resulting in improved antitumor activity in vivo.
Pharmaceutical research 2005;22(6):933-9.
2005: Jian-cheng Wang; Xiao-yan Liu; Wan-liang Lü; How-Sung Lee; Boon Cher Goh; Qiang Zhang
[The in vitro cytotoxicity and in vivo toxicity of doxorubicin antiresistant stealth liposomes].
Yao xue xue bao = Acta pharmaceutica Sinica 2005;40(5):475-80.
2005: Yuling Liu; Zhizhong Ma; Mark O M Tso; Qiang Zhang
Frosted branch angiitis secondary to macular choroidal neovascularization in a chinese woman.
Japanese journal of ophthalmology 2005;49(3):228-30.
2005: Shuang-Qing Zhang; Xu-Ying Zhong; Wan-Liang Lu; Li Zheng; Xuan Zhang; Feng Sun; Gui-Ying Fu; Qiang Zhang
Pharmacodynamics and pharmacokinetics of the insulin-mimetic agent vanadyl acetylacetonate in non-diabetic and diabetic rats.
Journal of inorganic biochemistry 2005;99(5):1064-75.
2005: Li Yang; Xian-rong Qi; Jing Shi; Wen-qian Chen; Qiang Zhang
[Preparation of 8-chloro-adenosine long circulation liposomes and its pharmacokinetics in rats].
Yao xue xue bao = Acta pharmaceutica Sinica 2005;40(4):382-4.
2005: Xue-nong Zhang; Xue-Ying Yan; Li-Hua Tang; Jin-hong Gong; Qiang Zhang
[Preparation, identification and inclusion actions of irisquinone hydroxypropyl-beta-cyclodextrin inclusion complex].
Yao xue xue bao = Acta pharmaceutica Sinica 2005;40(4):369-72.
2005: Qiang Zhang; Ximing Yang; Michael Pins; Borko Javonovic; Timothy Kuzel; Seong-Jin Kim; Luk Van Parijs; Norman M Greenberg; Victoria C Liu; Yinglu Guo; Chung Lee
Adoptive transfer of tumor-reactive transforming growth factor-beta-insensitive CD8+ T cells: eradication of autologous mouse prostate cancer.
Cancer research 2005;65(5):1761-9.
2005: Yu Liu; Wan-Liang Lu; Xuan Zhang; Xue-Qing Wang; Hua Zhang; Qiang Zhang
Pharmacodynamics and pharmacokinetics of recombinant hirudin via four non-parenteral routes.
Peptides 2005;26(3):423-30.
2005: Qiang Zhang; Jonathan N Rubenstein; Victoria C Liu; Irwin Park; Thomas Jang; Chung Lee
Restoration of expression of transforming growth factor-beta type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2'-deoxycytidine.
Life sciences 2005;76(10):1159-66.
2004: Jun-dong Dai; Xue-Qing Wang; Tao Zhang; Meng Meng; Xuan Zhang; Wan-liang Lü; Qiang Zhang
[Preparation of cyclosporine A pH sensitive nanoparticles and oral pharmacokinetics in rats].
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(12):1023-7.
2004: Wan-Liang Lu; Qiang Zhang; Li Zheng; Hua Wang; Rong-Yu Li; Li-Feng Zhang; Wen-Bin Shen; Xi-De Tu
Antipyretic, analgesic and anti-inflammatory activities of ketoprofen beta-cyclodextrin inclusion complexes in animals.
Biological & pharmaceutical bulletin 2004;27(10):1515-20.
2004: Shaoyun Yu; Ying Zhao; Fenglan Wu; Xuan Zhang; Wan-liang Lü; Hua Zhang; Qiang Zhang
Nasal insulin delivery in the chitosan solution: in vitro and in vivo studies.
International journal of pharmaceutics 2004;281(1-2):11-23.
2004: Jundong Dai; Tsuneji Nagai; Xueqing Wang; Tao Zhang; Meng Meng; Qiang Zhang
pH-sensitive nanoparticles for improving the oral bioavailability of cyclosporine A.
International journal of pharmaceutics 2004;280(1-2):229-40.
2004: Xue-Qing Wang; Jun-dong Dai; Zhen Chen; Tao Zhang; Gui-min Xia; Tsuneji Nagai; Qiang Zhang
Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration.
Journal of controlled release : official journal of the Controlled Release Society 2004;97(3):421-9.
2004: Wan-Liang Lu; Xian-rong Qi; Qiang Zhang; Rong-Yu Li; Gui-Lin Wang; Rui-Juan Zhang; Shu-li Wei
A pegylated liposomal platform: pharmacokinetics, pharmacodynamics, and toxicity in mice using doxorubicin as a model drug.
Journal of pharmacological sciences 2004;95(3):381-9.
2004: Xu-ying Zhong; Hua Zhang; Xuan Zhang; Wan-liang Lv; Qiang Zhang
[Hypoglycemic effects of bis(maltolato)oxovanadium administered by different routes upon diabetic rats].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2004;36(3):313-8.
2004: Zhao-gang Yang; Huan Meng; Xuan Zhang; Xiao-dan Li; Wan-liang Lv; Qiang Zhang
[Effect of quercetin on the acyclovir intestinal absorption].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2004;36(3):309-12.
2004: Xun-qing Wang; Zhen Chen; Jun-dong Dai; Tao Zhang; Gui-min Xia; Qiang Zhang
[Influence of suspending agents on relative bioavailability of cyclosporine A-loaded HPMCP nanoparticles for oral administration to rats].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2004;36(3):305-8.
2004: Xue-Qing Wang; Jun-dong Dai; Qiang Zhang; Tao Zhang; Gui-min Xia
[Relative bioavailability of cyclosporine A-loaded hydroxypropyl methylcellulose phthalate nanoparticles for oral administration in rats].
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(6):463-6.
2004: Zhi-ying Wang; Yue Zhang; Qiang Zhang
[Transport of proteins and peptides across human cultured alveolar A549 cell monolayers].
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(5):392-5.
2004: Kuang-shi Wu; Jin-tian Tang; Xuan Liu; Qiang Zhang
[Preparation of magnetoliposomes and its in vivo behavior on ICR mice].
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(4):288-91.
2004: Xueying Yan; Xiangtao Wang; Xuenong Zhang; Qiang Zhang
Gastrointestinal absorption of recombinant hirudin-2 in rats.
The Journal of pharmacology and experimental therapeutics 2004;308(2):774-9.
2004: Zhiying Wang; Qiang Zhang
Transport of proteins and peptides across human cultured alveolar A549 cell monolayer.
International journal of pharmaceutics 2004;269(2):451-6.
2004: Tianyan Zhou; Guoshu Chen; Yifan Wang; Qiang Zhang; Ming Yang; Tianhu Li
Synthesis of unimolecularly circular G-quadruplexes as prospective molecular probes.
Nucleic acids research 2004;32(21):e173.
2004: Xue-Ying Yan; Xue-nong Zhang; Qiang Zhang
[Absorption of recombinant hirudin in rats GI tract].
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(1):77-80.
2004: Xue-Qing Wang; Tao Zhang; Ying He; Liang Zhang; Qiang Zhang
[Study on preparation conditions for polylactide nanoparticles loaded cyclosporine A and its oral bioavailability in rats].
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(1):68-71.
2003: Kuangshi Wu; Ganlin Zhao; Shiqin Zhang; Qiang Zhang
[Development of sustained release tablet of tamoxifen citrate and its in vitro release profile].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2003;35(6):625-8.
2003: Zhi-Ying Wang; Qiang Zhang
[Study on pulmonary delivery of peptide drugs in rats: effects of absorption enhancers on cellular membrane fluidity].
Yao xue xue bao = Acta pharmaceutica Sinica 2003;38(12):957-61.
2003: Xuan Zhang; Li-xin Huang; Song-qing Nie; Xian-rong Qi; Qiang Zhang
[Secondary structure of insulin encapsulated within liposomes].
Yao xue xue bao = Acta pharmaceutica Sinica 2003;38(11):863-6.
2003: Zhiying Wang; Qiang Zhang
[Study on pulmonary delivery system of salmon calcitonin in rats].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2003;35(3):329-32.
2003: Xue-nong Zhang; Qiang Zhang; Hao Wen; Guo-quan Wang; Dian-jia Sun
[Preparation of albendazole polybutycyanocrylate nanoparticles and study on its pharmaceutical properties and tissue distribution].
Yao xue xue bao = Acta pharmaceutica Sinica 2003;38(6):462-6.
2003: Lei He; Gui-ling Wang; Qiang Zhang
[Studies on hypersensitivity and pharmacokinetics of paclitaxel microemulsion].
Yao xue xue bao = Acta pharmaceutica Sinica 2003;38(3):227-30.
2003: Lei He; Gui-ling Wang; Qiang Zhang
An alternative paclitaxel microemulsion formulation: hypersensitivity evaluation and pharmacokinetic profile.
International journal of pharmaceutics 2003;250(1):45-50.
2003: Wan-Liang Lu; Qiang Zhang; How-Sung Lee; Tian-Yan Zhou; Hua-Dong Sun; Da-Wei Zhang; Li Zheng; Michael Lee; Sai-Ming Wong
Total coenzyme Q10 concentrations in Asian men following multiple oral 50-mg doses administered as coenzyme Q10 sustained release tablets or regular tablets.
Biological & pharmaceutical bulletin 2003;26(1):52-5.
2002: Tian-zhi Yang; Xiang-Tao Wang; Xue-Ying Yan; Qiang Zhang
Phospholipid deformable vesicles for buccal delivery of insulin.
Chemical & pharmaceutical bulletin 2002;50(6):749-53.
2002: Xuan Zhang; Xian-rong Qi; Qiang Zhang
[Interaction between insulin with liposome].
Yao xue xue bao = Acta pharmaceutica Sinica 2002;37(5):370-3.
2002: Qiang Zhang; Lin Chen; Lili Liang; Zhijun Xi; Yi Ding; Ming Tong; Zhiwen Zhang; Chung Lee; Yinlu Guo
Renal cell carcinoma related novel gene, GYLZ-RCC18: cloning and functional studies.
Chinese medical journal 2002;115(5):746-9.
2002: Hua Zhang; Xian-rong Qi; Qiang Zhang
[Study on pharmaceutical characterization and pharmacokinetics of daunorubicin long-circulating liposomes in rat].
Yao xue xue bao = Acta pharmaceutica Sinica 2002;37(4):299-303.
2002: Da-bing Chen; Tian-zhi Yang; Wan-Liang Lu; Qiang Zhang
[In vitro and in vivo study of two kinds of long-circulating solid lipid nanoparticles containing paclitaxel].
Yao xue xue bao = Acta pharmaceutica Sinica 2002;37(1):54-8.
2001: Xuan Zhang; Qiang Zhang; Xian-rong Qi
[Structure characteristics of insulin liposomes].
Yao xue xue bao = Acta pharmaceutica Sinica 2001;36(6):448-51.
2001: Qiang Zhang; Z Shen; Tsuneji Nagai
Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats.
International journal of pharmaceutics 2001;218(1-2):75-80.
2001: Jing Wang; Qiang Zhang
Uptake of cyclosporine A loaded colloidal drug carriers by mouse peritoneal macrophages in vitro.
Acta pharmacologica Sinica 2001;22(1):57-61.
2000: Xian-rong Qi; Yoshie Maitani; Xin-pu Hou; Qiang Zhang; Shu-li Wei; Tsuneji Nagai
[Interactions of insulin with dipalmitoylphosphatidylcholine liposomes].
Yao xue xue bao = Acta pharmaceutica Sinica 2000;35(12):924-8.
2000: Qiang Zhang; Zheng Zhang; Dian-qi Xin; L Liang; Yanqun Na; Yinglu Guo
[Cloning and identifying of renal cell carcinoma differentially expressed genes].
Zhonghua wai ke za zhi [Chinese journal of surgery] 2000;38(12):935-8.