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Yi Zhang

Research Profile

Chemicals & Drugs

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Methylation

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Mouse

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Publications

TOP 3
Ming Lu; Kamil Ugurbil; Yi Zhang; Wei Chen; Xiao-Hong Zhu
In vitro and in vivo studies of (17) O NMR sensitivity at 9.4 and 16.4 T.
Li Shen; Hao Wu; Shinpei Yamaguchi; Kun Zhang; Ana C D'Alessio; Dinh Diep; Ho-Lim Fung; Yi Zhang
Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics.
Yi Zhang; He Zhu; Jin-Shun Liu; Gang Wang; Cheng-Fan Yu; Yan-Qun Na
Training for percutaneous renal access on a virtual reality simulator.

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All Publications

2013: Ming Lu; Kamil Ugurbil; Yi Zhang; Wei Chen; Xiao-Hong Zhu
In vitro and in vivo studies of (17) O NMR sensitivity at 9.4 and 16.4 T.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2013;69(6):1523-7.
2013: Li Shen; Hao Wu; Shinpei Yamaguchi; Kun Zhang; Ana C D'Alessio; Dinh Diep; Ho-Lim Fung; Yi Zhang
Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics.
Cell 2013;153(3):692-706.
2013: Yi Zhang; He Zhu; Jin-Shun Liu; Gang Wang; Cheng-Fan Yu; Yan-Qun Na
Training for percutaneous renal access on a virtual reality simulator.
Chinese medical journal 2013;126(8):1528-31.
2013: He Zhu; Jin-Shun Liu; Gang Wang; Cheng-Fan Yu; Yi Zhang; Yan-Qun Na
Virtual reality simulator for training urologists on transurethral prostatectomy.
Chinese medical journal 2013;126(7):1220-3.
2013: Kazuhiro Mochizuki; Qing Tong; Fang Xie; Hideo Yagita; Yajun Guo; Shan He; Koji Kato; Yongnian Liu; Shin Mineishi; Izumi Mochizuki; Yi Zhang
Delta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(7):3772-82.
2013: Li Xiao; Xiuzhen Xie; Wei Yue; Yi Zhang; Mahendra D Chordia; Leland W K Chung; Ji-Ping Wang; Dongfeng Pan
Heptamethine cyanine based (64)Cu-PET probe PC-1001 for cancer imaging: synthesis and in vivo evaluation.
Nuclear medicine and biology 2013;40(3):351-60.
2013: Yi Zhang; Changli Wang; Dongsheng Yue; Fang Zhang; Biao He; Jianxing He; David M Jablons; Hui Li; Natalie Lui
SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma.
Journal of experimental & clinical cancer research : CR 2013;32():7.
2013: Wei Jiang; Jinzhao Wang; Yi Zhang
Histone H3K27me3 demethylases KDM6A and KDM6B modulate definitive endoderm differentiation from human ESCs by regulating WNT signaling pathway.
Cell research 2013;23(1):122-30.
2012: Shinpei Yamaguchi; Kun Zhang; Dinh Diep; Kwonho Hong; Azusa Inoue; Rui Liu; Li Shen; Yi Zhang
Tet1 controls meiosis by regulating meiotic gene expression.
Nature 2012;492(7429):443-7.
2012: Jian-liang Cai; Ning-chen Li; Guo-feng Sun; Xiang-hua Zhang; Yi Zhang; Yan-qun Na
[Value of laparoscopic virtual reality simulator in laparoscopic suture ability training of catechumen].
Zhonghua wai ke za zhi [Chinese journal of surgery] 2012;50(12):1096-8.
2012: Susanne M Rafelski; Kurt S Thorn; Matheus P Viana; Phoebe Yam; Yi Zhang; Yee-Hung M Chan; Luciano da F Costa; Jennifer C Fung; Hao Li; Wallace F Marshall
Mitochondrial network size scaling in budding yeast.
Science (New York, N.Y.) 2012;338(6108):822-4.
2012: Zhi-Yong Zhang; Jin-Gang An; Zhi-Qiang Feng; Xi Gong; Yang He; Yi Zhang
[Evaluation of the navigation system for orbital wall reconstruction in unilateral orbital fractures].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2012;47(11):657-61.
2012: Xiao-Jing Liu; Jin-Gang An; Xi Gong; Chuan-bin Guo; Yang He; Yi Zhang
[Application of computer navigation system in the treatment of post-traumatic reconstruction].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2012;47(11):645-50.
2012: Yi Zhang; Abhijit S Dighe; James N Irvine; Vedavathi Madhu; Quanjun Cui
Osteogenic response of human adipose-derived stem cells to BMP-6, VEGF, and combined VEGF plus BMP-6 in vitro.
Growth factors (Chur, Switzerland) 2012;30(5):333-43.
2012: Liuh-Yow Chen; Hezhi Fang; Sok Ho Kim; Hongzhi Li; Zhenhua Luo; Li Qin; Benjamin P Tu; Jianming Xu; Patricia Yotnda; Qinfen Zhang; Yi Zhang; Yidong Bai; Zhou Songyang
Mitochondrial localization of telomeric protein TIN2 links telomere regulation to metabolic control.
Molecular cell 2012;47(6):839-50.
2012: Li Xiao; Yi Zhang; Stuart S Berr; Mahendra D Chordia; Patcharin Pramoonjago; Lin Pu; Dongfeng Pan
A novel near-infrared fluorescence imaging probe for in vivo neutrophil tracking.
Molecular imaging 2012;11(5):372-82.
2012: Fei Du; Yi Zhang; Xiao-Hong Zhu; Wei Chen
Simultaneous measurement of glucose blood-brain transport constants and metabolic rate in rat brain using in-vivo 1H MRS.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(9):1778-87.
2012: Zhengwei Xie; Yi Zhang; Ke Zou; Onn Brandman; Chunxiong Luo; Qi Ouyang; Hao Li
Molecular phenotyping of aging in single yeast cells using a novel microfluidic device.
Aging cell 2012;11(4):599-606.
2012: Li Xiao; Yaqin Xu; Zequan Yang; Yi Zhang; Mahendra D Chordia; Bijoy Kundu; Dongfeng Pan
Synthesis of PECAM-1-specific 64Cu PET imaging agent: evaluation of myocardial infarction caused by ischemia-reperfusion injury in mouse.
Bioorganic & medicinal chemistry letters 2012;22(12):4144-7.
2012: Fei Du; Yi Zhang; Wei Chen
Relayed magnetization transfer from nuclear Overhauser effect and chemical exchange observed by in vivo ³¹P MRS in rat brain.
Magnetic resonance imaging 2012;30(5):716-21.
2012: Gaoyang Liang; Jin He; Yi Zhang
Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming.
Nature cell biology 2012;14(5):457-66.
2012: Peng Gao; Jacob R Jokisaari; Jiangyu Li; Yuanming Liu; Christopher T Nelson; Seung-Hyub Baek; Chung Wung Bark; Chang-Beom Eom; Enge Wang; Yi Zhang; Xiaoqing Pan
Direct observations of retention failure in ferroelectric memories.
Advanced materials (Deerfield Beach, Fla.) 2012;24(8):1106-10.
2012: Shan He; Koji Kato; Rork Kuick; Yongnian Liu; Ram-Shankar Mani; Victor E Marquez; Shin Mineishi; Kazuhiro Mochizuki; Evelyn Nieves; Sooryanarayana Lnu; J Wang; Fang Xie; Arul M Chinnaiyan; Yi Zhang
Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
Blood 2012;119(5):1274-82.
2012: Yi Zhang; Ke Zou; Onn Brandman; Chunxiong Luo; Qi Ouyang; Zhengwei Xie; Hao Li
Single cell analysis of yeast replicative aging using a new generation of microfluidic device.
PloS one 2012;7(11):e48275.
2012: Li Shen; Yi Zhang
Enzymatic analysis of Tet proteins: key enzymes in the metabolism of DNA methylation.
Methods in enzymology 2012;512():93-105.
2011: Azusa Inoue; Li Shen; Qing Dai; Chuan He; Yi Zhang
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development.
Cell research 2011;21(12):1670-6.
2011: Kazuhiro Mochizuki; Shan He; Yi Zhang
Notch and inflammatory T-cell response: new developments and challenges.
Immunotherapy 2011;3(11):1353-66.
2011: Azusa Inoue; Yi Zhang
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos.
Science (New York, N.Y.) 2011;334(6053):194.
2011: J Di; Yi Zhang; J Zheng
Reactivation of p53 by inhibiting Mdm2 E3 ligase: a novel antitumor approach.
Current cancer drug targets 2011;11(8):987-94.
2011: Shinsuke Ito; Li Shen; James A Swenberg; Susan C Wu; Leonard B Collins; Qing Dai; Chuan He; Yi Zhang
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Science (New York, N.Y.) 2011;333(6047):1300-3.
2011: Anh T Nguyen; Olena Taranova; Jin He; Yi Zhang
Essential role of DOT1L in maintaining normal adult hematopoiesis.
Cell research 2011;21(9):1370-3.
2011: Yazhong Tao; Yi Zhang; Ru Cao; Jianfu Chen; Zhan-Peng Huang; Suk-Won Jin; Ronald L Neppl; Ruhang Tang; Da-Zhi Wang
The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly.
The Journal of cell biology 2011;194(4):551-65.
2011: Susan C Wu; Yi Zhang
Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability.
The Journal of biological chemistry 2011;286(32):28511-9.
2011: H W Jang; D A Felker; C W Bark; Yuhuang Wang; M K Niranjan; C T Nelson; Yi Zhang; D Su; C M Folkman; S H Baek; Sang Bok Lee; K Janicka; Yingxi Zhu; XQ Pan; D D Fong; Evgeny Y Tsymbal; M S Rzchowski; Chang-Beom Eom
Metallic and insulating oxide interfaces controlled by electronic correlations.
Science (New York, N.Y.) 2011;331(6019):886-9.
2011: Christopher T Nelson; Benjamin Winchester; Yi Zhang; Sung-Joo Kim; Alexander Melville; Carolina Adamo; Chad M Folkman; Seung-Hyub Baek; Chang-Beom Eom; Darrell G Schlom; LQ Chen; Xiaoqing Pan
Spontaneous vortex nanodomain arrays at ferroelectric heterointerfaces.
Nano letters 2011;11(2):828-34.
2011: Anh T Nguyen; Bin Xiao; Ronald L Neppl; Eric M Kallin; J Li; Taiping Chen; Da-Zhi Wang; Xiao Xiao; Yi Zhang
DOT1L regulates dystrophin expression and is critical for cardiac function.
Genes & development 2011;25(3):263-74.
2011: Yi Zhang; Ashley R Sandy; J Wang; Vedran Radojcic; Gloria T Shan; Ivy T Tran; Ann Friedman; Koji Kato; Shan He; Shuaiying Cui; Elizabeth Hexner; Dale M Frank; Stephen G Emerson; Warren S Pear; Ivan P Maillard
Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.
Blood 2011;117(1):299-308.
2011: Shan He; Koji Kato; Jiu Jiang; Daniel R Wahl; Shin Mineishi; Erin M Fisher; Donna M Murasko; Gary D Glick; Yi Zhang
Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells.
PloS one 2011;6(5):e20107.
2010: P Palazzo; C Balucani; K Barlinn; Georgios Tsivgoulis; Yi Zhang; L Zhao; J Dewolfe; B Toaldo; E Stamboulis; F Vernieri; P M Rossini; Andrei V Alexandrov
Association of reversed Robin Hood syndrome with risk of stroke recurrence.
Neurology 2010;75(22):2003-8.
2010: Yi Zhang; Li Xiao; Mahendra D Chordia; Landon W Locke; Mark B Williams; Stuart S Berr; Dongfeng Pan
Neutrophil targeting heterobivalent SPECT imaging probe: cFLFLF-PEG-TKPPR-99mTc.
Bioconjugate chemistry 2010;21(10):1788-93.
2010: Susan C Wu; Eric M Kallin; Yi Zhang
Role of H3K27 methylation in the regulation of lncRNA expression.
Cell research 2010;20(10):1109-16.
2010: Jin He; Yi Zhang
Janus kinase 2: an epigenetic 'writer' that activates leukemogenic genes.
Journal of molecular cell biology 2010;2(5):231-3.
2010: Susan C Wu; Yi Zhang
Active DNA demethylation: many roads lead to Rome.
Nature reviews. Molecular cell biology 2010;11(9):607-20.
2010: Gaoyang Liang; Olena Taranova; Kai Xia; Yi Zhang
Butyrate promotes induced pluripotent stem cell generation.
The Journal of biological chemistry 2010;285(33):25516-21.
2010: C Deisenroth; Yi Zhang
Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway.
Oncogene 2010;29(30):4253-60.
2010: Li Xiao; Yi Zhang; Zhongqiu Liu; Min Yang; Lin Pu; Dongfeng Pan
Synthesis of the Cyanine 7 labeled neutrophil-specific agents for noninvasive near infrared fluorescence imaging.
Bioorganic & medicinal chemistry letters 2010;20(12):3515-7.
2010: Koji Kato; Shuaiying Cui; Rork Kuick; Shin Mineishi; Elizabeth Hexner; James L M Ferrara; Stephen G Emerson; Yi Zhang
Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(6):751-71.
2010: Michael D Sheets; B Fritz; R S Hartley; Yi Zhang
Polyribosome analysis for investigating mRNA translation in Xenopus oocytes, eggs and embryos.
Methods (San Diego, Calif.) 2010;51(1):152-6.
2010: Marta Rubiera; Luis Cava; Georgios Tsivgoulis; Damon E Patterson; Limin Zhao; Yi Zhang; Aaron M Anderson; Alice Robinson; Mark R Harrigan; Edward Underwood; Joseph Horton; Andrei V Alexandrov
Diagnostic criteria and yield of real-time transcranial Doppler monitoring of intra-arterial reperfusion procedures.
Stroke; a journal of cerebral circulation 2010;41(4):695-9.
2010: Jee Young An; Eun-A Kim; Yonghua Jiang; Adriana Zakrzewska; Dong Eun Kim; Min Jae Lee; Inhee Mook-Jung; Yi Zhang; Yong Tae Kwon
UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(5):1912-7.
2010: Yuki Okada; Kazuo Yamagata; Kwonho Hong; Teruhiko Wakayama; Yi Zhang
A role for the elongator complex in zygotic paternal genome demethylation.
Nature 2010;463(7280):554-8.
2010: Michelle S Hsiang; Elizabeth J Carlton; Yi Zhang; Bo Zhong; Qiu Dongchuan; Pierre-Alain Cohen; Christopher C Stewart; Robert C Spear
Use of ultrasonography to evaluate Schistosoma japonicum-related morbidity in children, Sichuan Province, China, 2000-2007.
The American journal of tropical medicine and hygiene 2010;82(1):103-11.
2010: Yuki Okada; Keisuke Tateishi; Yi Zhang
Histone demethylase JHDM2A is involved in male infertility and obesity.
Journal of andrology 2010;31(1):75-8.
2009: Tao Lu; Mark Jackson; Aatur D Singhi; Eugene S Kandel; Maojing Yang; Yi Zhang; Andrei V Gudkov; George R Stark
Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16339-44.
2009: Susan C Wu; Yi Zhang
Minireview: role of protein methylation and demethylation in nuclear hormone signaling.
Molecular endocrinology (Baltimore, Md.) 2009;23(9):1323-34.
2009: Eric M Kallin; Ru Cao; Raja Jothi; Kai Xia; Kairong Cui; Keji Zhao; Yi Zhang
Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes.
PLoS genetics 2009;5(6):e1000506.
2009: Keisuke Tateishi; Yuki Okada; Eric M Kallin; Yi Zhang
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance.
Nature 2009;458(7239):757-61.
2009: Nara Lee; Hediye Erdjument-Bromage; Paul Tempst; Richard S Jones; Yi Zhang
The H3K4 demethylase lid associates with and inhibits histone deacetylase Rpd3.
Molecular and cellular biology 2009;29(6):1401-10.
2008: Keisuke Tateishi; Jin He; Olena Taranova; Gaoyang Liang; Ana C D'Alessio; Yi Zhang
Generation of insulin-secreting islet-like clusters from human skin fibroblasts.
The Journal of biological chemistry 2008;283(46):31601-7.
2008: Jin He; Eric M Kallin; Yu-Ichi Tsukada; Yi Zhang
The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b).
Nature structural & molecular biology 2008;15(11):1169-75.
2008: Nara Lee; Yi Zhang
Chemical answers to epigenetic crosstalk.
Nature chemical biology 2008;4(6):335-7.
2008: Jiancong Liang; Ma Wan; Yi Zhang; Peili Gu; Huawei Xin; Sung Yun Jung; Jun Qin; Jiemin Wong; Austin J Cooney; Dan Liu; Zhou Songyang
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.
Nature cell biology 2008;10(6):731-9.
2008: Xiangdong Lu; Grigoriy I Kovalev; Hua Chang; Eric Kallin; Geoffrey Knudsen; Li Xia; Nilamadhab Mishra; Phillip Ruiz; En Li; Lishan Su; Yi Zhang
Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice.
The Journal of biological chemistry 2008;283(20):13825-33.
2008: Ru Cao; Hengbin Wang; Jin He; Hediye Erdjument-Bromage; Paul Tempst; Yi Zhang
Role of hPHF1 in H3K27 methylation and Hox gene silencing.
Molecular and cellular biology 2008;28(5):1862-72.
2008: Brendan Jones; Hui Su; Audesh Bhat; Hong Lei; Jeffrey Bajko; Sarah Hevi; Gretchen A Baltus; Shilpa Kadam; Huili Zhai; Reginald Valdez; Susana Gonzalo; Yi Zhang; En Li; Taiping Chen
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
PLoS genetics 2008;4(9):e1000190.
2007: C David Allis; Shelley L Berger; Jacques Cote; Sharon Dent; Thomas Jenuwien; Tony Kouzarides; Lorraine Pillus; Danny Reinberg; Yang Shi; Ramin Shiekhattar; Ali Shilatifard; Jerry Workman; Yi Zhang
New nomenclature for chromatin-modifying enzymes.
Cell 2007;131(4):633-6.
2007: Robert J Klose; Yi Zhang
Histone H3 Arg2 methylation provides alternative directions for COMPASS.
Nature structural & molecular biology 2007;14(11):1058-60.
2007: Yuki Okada; Greg Scott; Manas K Ray; Yuji Mishina; Yi Zhang
Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis.
Nature 2007;450(7166):119-23.
2007: Jia Fang; Gregory J Hogan; Gaoyang Liang; Jason Dillon Lieb; Yi Zhang
The Saccharomyces cerevisiae histone demethylase Jhd1 fine-tunes the distribution of H3K36me2.
Molecular and cellular biology 2007;27(13):5055-65.
2007: Cyrus Martin; Yi Zhang
Mechanisms of epigenetic inheritance.
Current opinion in cell biology 2007;19(3):266-72.
2007: Robert J Klose; Kathryn E Gardner; Gaoyang Liang; Hediye Erdjument-Bromage; Paul Tempst; Yi Zhang
Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae?
Molecular and cellular biology 2007;27(11):3951-61.
2007: Nara Lee; Junyu Zhang; Robert J Klose; Hediye Erdjument-Bromage; Paul Tempst; Richard S Jones; Yi Zhang
The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase.
Nature structural & molecular biology 2007;14(4):341-3.
2007: Robert J Klose; Yi Zhang
Regulation of histone methylation by demethylimination and demethylation.
Nature reviews. Molecular cell biology 2007;8(4):307-18.
2007: Kenichi Yamane; Keisuke Tateishi; Robert J Klose; Jia Fang; Laura A Fabrizio; Hediye Erdjument-Bromage; Joyce Taylor-Papadimitriou; Paul Tempst; Yi Zhang
PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.
Molecular cell 2007;25(6):801-12.
2007: Robert J Klose; Qin Yan; Zuzana Tothova; Kenichi Yamane; Hediye Erdjument-Bromage; Paul Tempst; D Gary Gilliland; Yi Zhang; William G Kaelin
The retinoblastoma binding protein RBP2 is an H3K4 demethylase.
Cell 2007;128(5):889-900.
2007: Gaoyang Liang; Robert J Klose; Kathryn E Gardner; Yi Zhang
Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase.
Nature structural & molecular biology 2007;14(3):243-5.
2007: Yojiro Kotake; Ru Cao; Patrick Viatour; Julien Sage; Yi Zhang; Yue Xiong
pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.
Genes & development 2007;21(1):49-54.
2006: Yu-ichi Tsukada; Yi Zhang
Purification of histone demethylases from HeLa cells.
Methods (San Diego, Calif.) 2006;40(4):318-26.
2006: Laurel B Bender; Jinkyo Suh; Coleen R Carroll; Youyi Fong; Ian M Fingerman; Scott D Briggs; Ru Cao; Yi Zhang; Valerie Reinke; Susan Strome
MES-4: an autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line.
Development (Cambridge, England) 2006;133(19):3907-17.
2006: Yong Chen; Yuting Yang; Feng Wang; Ke Wan; Kenichi Yamane; Yi Zhang; Ming Lei
Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):13956-61.
2006: Robert J Klose; Eric M Kallin; Yi Zhang
JmjC-domain-containing proteins and histone demethylation.
Nature reviews. Genetics 2006;7(9):715-27.
2006: Yuki Okada; Qi Jiang; Margot Lemieux; Lucie Jeannotte; Lishan Su; Yi Zhang
Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L.
Nature cell biology 2006;8(9):1017-24.
2006: Zhizhong Li; Ru Cao; Ming Wang; Michael P Myers; Yi Zhang; Rui-Ming Xu
Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex.
The Journal of biological chemistry 2006;281(29):20643-9.
2006: Robert J Klose; Kenichi Yamane; Yangjin Bae; Dianzheng Zhang; Hediye Erdjument-Bromage; Paul Tempst; Jiemin Wong; Yi Zhang
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.
Nature 2006;442(7100):312-6.
2006: Yi Zhang
It takes a PHD to interpret histone methylation.
Nature structural & molecular biology 2006;13(7):572-4.
2006: Hengbin Wang; Ling Zhai; Jun Xu; Heui-Yun Joo; Sarah Jackson; Hediye Erdjument-Bromage; Paul Tempst; Yue Xiong; Yi Zhang
Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage.
Molecular cell 2006;22(3):383-94.
2006: Kenichi Yamane; Charalambos Toumazou; Yu-ichi Tsukada; Hediye Erdjument-Bromage; Paul Tempst; Jiemin Wong; Yi Zhang
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.
Cell 2006;125(3):483-95.
2006: Ying Huang; Jia Fang; Mark T Bedford; Yi Zhang; Rui-Ming Xu
Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A.
Science (New York, N.Y.) 2006;312(5774):748-51.
2006: Thusanth Thuraisingam; Hakeem Sam; Jacques Moisan; Yi Zhang; Aihao Ding; Danuta Radzioch
Delayed cutaneous wound healing in mice lacking solute carrier 11a1 (formerly Nramp1): correlation with decreased expression of secretory leukocyte protease inhibitor.
The Journal of investigative dermatology 2006;126(4):890-901.
2006: Jeesun Kim; Jeremy Daniel; Alexsandra Espejo; Aimee Lake; Murli Krishna; Li Xia; Yi Zhang; Mark T Bedford
Tudor, MBT and chromo domains gauge the degree of lysine methylation.
EMBO reports 2006;7(4):397-403.
2006: Cyrus Martin; Ru Cao; Yi Zhang
Substrate preferences of the EZH2 histone methyltransferase complex.
The Journal of biological chemistry 2006;281(13):8365-70.
2006: Yu-ichi Tsukada; Jia Fang; Hediye Erdjument-Bromage; Maria E Warren; Christoph H Borchers; Paul Tempst; Yi Zhang
Histone demethylation by a family of JmjC domain-containing proteins.
Nature 2006;439(7078):811-6.
2006: Nirit Feldman; Ariela Gerson; Jia Fang; En Li; Yi Zhang; Yoichi Shinkai; Howard Cedar; Yehudit Bergman
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.
Nature cell biology 2006;8(2):188-94.
2005: Ru Cao; Yu-Ichi Tsukada; Yi Zhang
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.
Molecular cell 2005;20(6):845-54.
2005: Cyrus Martin; Yi Zhang
The diverse functions of histone lysine methylation.
Nature reviews. Molecular cell biology 2005;6(11):838-49.
2005: Cecile C de la Cruz; Jia Fang; Kathrin Plath; Kathleen A Worringer; Dmitri A Nusinow; Yi Zhang; Barbara Panning
Developmental regulation of Suz 12 localization.
Chromosoma 2005;114(3):183-92.
2005: Yuki Okada; Qin Feng; Yihui Lin; Qi Jiang; Yaqiang Li; Vernon M Coffield; Lishan Su; Guoliang Xu; Yi Zhang
hDOT1L links histone methylation to leukemogenesis.
Cell 2005;121(2):167-78.
2005: George N Tzimas; Eric Chevet; Sarah Jenna; Duc Thang Nguyên; Abdel-Majid Khatib; Victoria A Marcus; Yi Zhang; Michel Chrétien; Nabil G Seidah; Peter Metrakos
Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases.
BMC cancer 2005;5():149.
2004: Jia Fang; Taiping Chen; Brian Chadwick; En Li; Yi Zhang
Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation.
The Journal of biological chemistry 2004;279(51):52812-5.
2004: David Umlauf; Yuji Goto; Ru Cao; Frédérique Cerqueira; Alexandre Wagschal; Yi Zhang; Robert Feil
Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes.
Nature genetics 2004;36(12):1296-300.
2004: Hengbin Wang; Liangjun Wang; Hediye Erdjument-Bromage; Miguel Vidal; Paul Tempst; Richard S Jones; Yi Zhang
Role of histone H2A ubiquitination in Polycomb silencing.
Nature 2004;431(7010):873-8.
2004: Yi Zhang
Molecular biology: no exception to reversibility.
Nature 2004;431(7009):637-9.
2004: Laurel B Bender; Ru Cao; Yi Zhang; Susan Strome
The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans.
Current biology : CB 2004;14(18):1639-43.
2004: Ru Cao; Yi Zhang
SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex.
Molecular cell 2004;15(1):57-67.
2004: Liangjun Wang; J Lesley Brown; Ru Cao; Yi Zhang; Judith A Kassis; Richard S Jones
Hierarchical recruitment of polycomb group silencing complexes.
Molecular cell 2004;14(5):637-46.
2004: Ru Cao; Yi Zhang
The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.
Current opinion in genetics & development 2004;14(2):155-64.
2004: Yi Zhang; Ru Cao; Liangjun Wang; Richard S Jones
Mechanism of Polycomb group gene silencing.
Cold Spring Harbor symposia on quantitative biology 2004;69():309-17.
2004: Jia Fang; Hengbin Wang; Yi Zhang
Purification of histone methyltransferases from HeLa cells.
Methods in enzymology 2004;377():213-26.
2003: Yi Zhang
Transcriptional regulation by histone ubiquitination and deubiquitination.
Genes & development 2003;17(22):2733-40.
2003: Hengbin Wang; Woojin An; Ru Cao; Li Xia; Hediye Erdjument-Bromage; Bruno Chatton; Paul Tempst; Robert G Roeder; Yi Zhang
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression.
Molecular cell 2003;12(2):475-87.
2003: Jinrong Min; Yi Zhang; Rui-Ming Xu
Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27.
Genes & development 2003;17(15):1823-8.
2003: Hogune Im; Changwon Park; Qin Feng; Kirby D Johnson; Carol M Kiekhaefer; Kyunghee Choi; Yi Zhang; Emery H Bresnick
Dynamic regulation of histone H3 methylated at lysine 79 within a tissue-specific chromatin domain.
The Journal of biological chemistry 2003;278(20):18346-52.
2003: Kathrin Plath; Jia Fang; Susanna Mlynarczyk-Evans; Ru Cao; Kathleen A Worringer; Hengbin Wang; Cecile C de la Cruz; Arie P Otte; Barbara Panning; Yi Zhang
Role of histone H3 lysine 27 methylation in X inactivation.
Science (New York, N.Y.) 2003;300(5616):131-5.
2003: Jinrong Min; Qin Feng; Zhizhong Li; Yi Zhang; Rui-Ming Xu
Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase.
Cell 2003;112(5):711-23.
2003: Dale A Ramsden; Yi Zhang
Everything is E(Z): linking histone methylation to B cell development.
Nature immunology 2003;4(2):101-3.
2003: Qin Feng; Yi Zhang
The NuRD complex: linking histone modification to nucleosome remodeling.
Current topics in microbiology and immunology 2003;274():269-90.
2003: Adam Wood; Nevan J Krogan; Jim Dover; Jessica Schneider; Jonathan Heidt; Marry Ann Boateng; Kimberly Dean; Ashkan Golshani; Yi Zhang; Jack F Greenblatt; Mark Johnston; Ali Shilatifard
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter.
Molecular cell 2003;11(1):267-74.
2002: Rabah Iratni; Yu-Ting Yan; Canhe Chen; Jixiang Ding; Yi Zhang; Sandy M Price; Danny Reinberg; Michael M Shen
Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1.
Science (New York, N.Y.) 2002;298(5600):1996-9.
2002: Ru Cao; Liangjun Wang; Hengbin Wang; Li Xia; Hediye Erdjument-Bromage; Paul Tempst; Richard S Jones; Yi Zhang
Role of histone H3 lysine 27 methylation in Polycomb-group silencing.
Science (New York, N.Y.) 2002;298(5595):1039-43.
2002: Huck-Hui Ng; Rui-Ming Xu; Yi Zhang; Kevin Struhl
Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79.
The Journal of biological chemistry 2002;277(38):34655-7.
2002: Jia Fang; Qin Feng; Carrie S Ketel; Hengbin Wang; Ru Cao; Li Xia; Hediye Erdjument-Bromage; Paul Tempst; Jeffrey A Simon; Yi Zhang
Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase.
Current biology : CB 2002;12(13):1086-99.
2002: Qin Feng; Hengbin Wang; Huck-Hui Ng; Hediye Erdjument-Bromage; Paul Tempst; Kevin Struhl; Yi Zhang
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Current biology : CB 2002;12(12):1052-8.
2002: Huck-Hui Ng; Qin Feng; Hengbin Wang; Hediye Erdjument-Bromage; Paul Tempst; Yi Zhang; Kevin Struhl
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association.
Genes & development 2002;16(12):1518-27.
2002: Andrei Kuzmichev; Yi Zhang; Hediye Erdjument-Bromage; Paul Tempst; Danny Reinberg
Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).
Molecular and cellular biology 2002;22(3):835-48.
2002: Liu Yang; Li Xia; Daniel Y Wu; Hengbin Wang; Howard A Chansky; William H Schubach; Dennis D Hickstein; Yi Zhang
Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.
Oncogene 2002;21(1):148-52.
2002: Qin Feng; Ru Cao; Li Xia; Hediye Erdjument-Bromage; Paul Tempst; Yi Zhang
Identification and functional characterization of the p66/p68 components of the MeCP1 complex.
Molecular and cellular biology 2002;22(2):536-46.
2001: Hongbing Wang; Ru Cao; Li Xia; Hediye Erdjument-Bromage; Christoph H Borchers; Paul Tempst; Yi Zhang
Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.
Molecular cell 2001;8(6):1207-17.
2001: Steven Jacobs; SEAN TAVERNA; Yi Zhang; Scott D Briggs; J Li; Joel C Eissenberg; C David Allis; Sepideh Khorasanizadeh
Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3.
The EMBO journal 2001;20(18):5232-41.
2001: Yi Zhang; D Reinberg
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails.
Genes & development 2001;15(18):2343-60.
2001: Hongbing Wang; Zhi-Qing Huang; Li Xia; Qin Feng; Hediye Erdjument-Bromage; Brian D Strahl; Scott D Briggs; C David Allis; Jiemin Wong; Paul Tempst; Yi Zhang
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor.
Science (New York, N.Y.) 2001;293(5531):853-7.
2001: H B Wang; Yi Zhang
Mi2, an auto-antigen for dermatomyositis, is an ATP-dependent nucleosome remodeling factor.
Nucleic acids research 2001;29(12):2517-21.
2001: Yi Zhang; Yue Xiong
A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation.
Science (New York, N.Y.) 2001;292(5523):1910-5.
2001: L Xia; Yi Zhang
Sp1 and ETS family transcription factors regulate the mouse Mta2 gene expression.
Gene 2001;268(1-2):77-85.
2001: Qin Feng; Yi Zhang
The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes.
Genes & development 2001;15(7):827-32.
2001: A Lai; Brian Kennedy; David A Barbie; Nicholas Bertos; Xiang-Jiao Yang; M C Theberge; S C Tsai; Edward Seto; Yi Zhang; Andrei Kuzmichev; William Stratton Lane; Danny Reinberg; Ed Harlow; Philip E Branton
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.
Molecular and cellular biology 2001;21(8):2918-32.
2000: Manabu Furukawa; Yi Zhang; Joseph F McCarville; Tomohiko Ohta; Yue Xiong
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
Molecular and cellular biology 2000;20(21):8185-97.
1999: HH Ng; Yi Zhang; Brian Hendrich; C A Johnson; Bryan M Turner; H Erdjument-Bromage; Paul Tempst; D Reinberg; Adrian Bird
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.
Nature genetics 1999;23(1):58-61.
1999: Yi Zhang; H H Ng; Hediye Erdjument-Bromage; Paul Tempst; A Bird; Danny Reinberg
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.
Genes & development 1999;13(15):1924-35.
1999: Yi Zhang; Yue Xiong
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53.
Molecular cell 1999;3(5):579-91.
1998: Yi Zhang; Gary LeRoy; H P Seelig; William Stratton Lane; Danny Reinberg
The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.
Cell 1998;95(2):279-89.
1998: X Sun; Yi Zhang; Helen Cho; P Rickert; Emma Lees; William Stratton Lane; Danny Reinberg
NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription.
Molecular cell 1998;2(2):213-22.
1998: Yi Zhang; Zu-Wen Sun; Rabah Iratni; Hediye Erdjument-Bromage; Paul Tempst; Michael Hampsey; Danny Reinberg
SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex.
Molecular cell 1998;1(7):1021-31.
1998: Yi Zhang; Yue Xiong; Wendell G Yarbrough
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways.
Cell 1998;92(6):725-34.
1997: Yi Zhang; Rabah Iratni; Hediye Erdjument-Bromage; Paul Tempst; Danny Reinberg
Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.
Cell 1997;89(3):357-64.
1996: Yi Zhang; L M Epstein
Cloning and characterization of extended hammerheads from a diverse set of caudate amphibians.
Gene 1996;172(2):183-90.
1994: Steven R Coats; Yi Zhang; L M Epstein
Transcription of satellite 2 DNA from the newt is driven by a snRNA type of promoter.
Nucleic acids research 1994;22(22):4697-704.
1991: L M Pabón-Peña; Yi Zhang; L M Epstein
Newt satellite 2 transcripts self-cleave by using an extended hammerhead structure.
Molecular and cellular biology 1991;11(12):6109-15.