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Yanping Zhang

Research Profile

Chemicals & Drugs

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Mouse

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Publications

TOP 3
Laura A Tollini; Yanping Zhang
p53 Regulation Goes Live-Mdm2 and MdmX Co-Star: Lessons Learned from Mouse Modeling.
Hilary V Clegg; Koji Itahana; Yoko Itahana; Sundhar Ramalingam; Yanping Zhang
Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.
Da-Qiang Li; Suresh B Pakala; Sirigiri Divijendra Natha Reddy; Kazufumi Ohshiro; Jun-Xiang Zhang; Lei Wang; Yanping Zhang; Ignacio Moreno de Alborán; M Radhakrishna Pillai; Jeyanthy Eswaran; Rakesh Kumar
Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis.

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All Publications

2012: Laura A Tollini; Yanping Zhang
p53 Regulation Goes Live-Mdm2 and MdmX Co-Star: Lessons Learned from Mouse Modeling.
Genes & cancer 2012;3(3-4):219-25.
2012: Hilary V Clegg; Koji Itahana; Yoko Itahana; Sundhar Ramalingam; Yanping Zhang
Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.
PloS one 2012;7(5):e38212.
2011: Da-Qiang Li; Suresh B Pakala; Sirigiri Divijendra Natha Reddy; Kazufumi Ohshiro; Jun-Xiang Zhang; Lei Wang; Yanping Zhang; Ignacio Moreno de Alborán; M Radhakrishna Pillai; Jeyanthy Eswaran; Rakesh Kumar
Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8791-6.
2011: Chad Deisenroth; Yanping Zhang
The Ribosomal Protein-Mdm2-p53 Pathway and Energy Metabolism: Bridging the Gap between Feast and Famine.
Genes & cancer 2011;2(4):392-403.
2011: Paula L Miliani de Marval; Yanping Zhang
The RP-Mdm2-p53 pathway and tumorigenesis.
Oncotarget 2011;2(3):234-8.
2011: Wenqi Pan; Sameer Issaq; Yanping Zhang
The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression.
PloS one 2011;6(6):e21625.
2010: Xinran Wang; Xin Wen; Craig S Criddle; H Yan; Yanping Zhang; K Ding
Bacterial community dynamics in two full-scale wastewater treatment systems with functional stability.
Journal of applied microbiology 2010;109(4):1218-26.
2010: Everardo Macias; Aiwen Jin; Chad Deisenroth; Krishna Bhat; Hua Mao; Mikael S Lindström; Yanping Zhang
An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction.
Cancer cell 2010;18(3):231-43.
2010: Chad Deisenroth; Aaron R Thorner; Takeharu Enomoto; Charles M Perou; Yanping Zhang
Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.
Molecular and cellular biology 2010;30(16):3981-93.
2010: Hilary V Clegg; Yanping Zhang
Regulation of the p53 tumor suppressor pathway: the problems and promises of studying Mdm2's E3 ligase function.
Critical reviews in eukaryotic gene expression 2010;20(1):77-86.
2009: Da-Qiang Li; Sirigiri Divijendra Natha Reddy; Suresh B Pakala; Xifeng Wu; Yanping Zhang; Suresh K Rayala; Rakesh Kumar
MTA1 coregulator regulates p53 stability and function.
The Journal of biological chemistry 2009;284(50):34545-52.
2009: Yanping Zhang; Hua Lu
Signaling to p53: ribosomal proteins find their way.
Cancer cell 2009;16(5):369-77.
2009: Da-Qiang Li; Kazufumi Ohshiro; Sirigiri Divijendra Natha Reddy; Suresh B Pakala; Mong-Hong Lee; Yanping Zhang; Suresh K Rayala; Rakesh Kumar
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17493-8.
2009: Wei Fu; Qiuping Ma; Lei Chen; Pengfei Li; Mu Zhang; Sivapriya Ramamoorthy; Zafar Nawaz; Tsukasa Shimojima; Hengbin Wang; Yonghua Yang; Zheng Shen; Yingtao Zhang; Xiaohong Zhang; Santo V Nicosia; Yanping Zhang; Jack W Pledger; Jiandong Chen; Wenlong Bai
MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.
The Journal of biological chemistry 2009;284(21):13987-4000.
2009: Min Huang; Koji Itahana; Yanping Zhang; Beverly S Mitchell
Depletion of guanine nucleotides leads to the Mdm2-dependent proteasomal degradation of nucleostemin.
Cancer research 2009;69(7):3004-12.
2009: Yoko Itahana; Hengming Ke; Yanping Zhang
p53 Oligomerization is essential for its C-terminal lysine acetylation.
The Journal of biological chemistry 2009;284(8):5158-64.
2009: Yanping Zhang; M Zhang; H Dong; S Yong; X Li; Nancy Olashaw; Patricia A Kruk; Jin Q Cheng; Wenlong Bai; Jiandong Chen; Santo V Nicosia; Xiaohong Zhang
Deacetylation of cortactin by SIRT1 promotes cell migration.
Oncogene 2009;28(3):445-60.
2008: Koji Itahana; Hilary V Clegg; Yanping Zhang
ARF in the mitochondria: the last frontier?
Cell cycle (Georgetown, Tex.) 2008;7(23):3641-6.
2008: Mikael Lindström; Yanping Zhang
Ribosomal protein S9 is a novel B23/NPM-binding protein required for normal cell proliferation.
The Journal of biological chemistry 2008;283(23):15568-76.
2008: Koji Itahana; Yanping Zhang
Mitochondrial p32 is a critical mediator of ARF-induced apoptosis.
Cancer cell 2008;13(6):542-53.
2008: Hilary V Clegg; Koji Itahana; Yanping Zhang
Unlocking the Mdm2-p53 loop: ubiquitin is the key.
Cell cycle (Georgetown, Tex.) 2008;7(3):287-92.
2008: Min Huang; Yanshan Ji; Koji Itahana; Yanping Zhang; Beverly S Mitchell
Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption.
Leukemia research 2008;32(1):131-41.
2007: Koji Itahana; Hua Mao; Aiwen Jin; Yoko Itahana; Hilary V Clegg; Mikael Lindström; Krishna P Bhat; Virginia L Godfrey; Gerard I Evan; Yanping Zhang
Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation.
Cancer cell 2007;12(4):355-66.
2007: Mikael Lindström; Chad Deisenroth; Yanping Zhang
Putting a finger on growth surveillance: insight into MDM2 zinc finger-ribosomal protein interactions.
Cell cycle (Georgetown, Tex.) 2007;6(4):434-7.
2007: Mikael Lindström; Aiwen Jin; Chad Deisenroth; Gabrielle White Wolf; Yanping Zhang
Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
Molecular and cellular biology 2007;27(3):1056-68.
2006: Mushui Dai; Dingding Shi; Yetao Jin; Xiao-Xin Sun; Yanping Zhang; Steven R Grossman; Hua lu
Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism.
The Journal of biological chemistry 2006;281(34):24304-13.
2006: Takeharu Enomoto; Mikael Lindström; Aiwen Jin; Hengming Ke; Yanping Zhang
Essential role of the B23/NPM core domain in regulating ARF binding and B23 stability.
The Journal of biological chemistry 2006;281(27):18463-72.
2006: Yanping Zhang; Lawrence A Trissel
Physical instability of frozen pemetrexed solutions in PVC bags.
The Annals of pharmacotherapy 2006;40(7-8):1289-92.
2006: Yoko Itahana; Edward T H Yeh; Yanping Zhang
Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2.
Molecular and cellular biology 2006;26(12):4675-89.
2006: Yanping Zhang; Lawrence A Trissel
Physical and chemical stability of pemetrexed in infusion solutions.
The Annals of pharmacotherapy 2006;40(6):1082-5.
2006: Mikael Lindström; Yanping Zhang
B23 and ARF: friends or foes?
Cell biochemistry and biophysics 2006;46(1):79-90.
2005: Yanping Zhang; Lawrence A Trissel
Physical and chemical stability of pemetrexed solutions in plastic syringes.
The Annals of pharmacotherapy 2005;39(12):2026-8.
2005: Judith A Erkmann; Eric J Wagner; Jian Dong; Yanping Zhang; Ulrike Kutay; William F Marzluff
Nuclear import of the stem-loop binding protein and localization during the cell cycle.
Molecular biology of the cell 2005;16(6):2960-71.
2005: Lawrence A Trissel; Yanping Zhang
Palonosetron HCl compatibility and stability with doxorubicin HCl and epirubicin HCl during simulated Y-site administration.
The Annals of pharmacotherapy 2005;39(2):280-3.
2004: Aiwen Jin; Koji Itahana; Kevin O'Keefe; Yanping Zhang
Inhibition of HDM2 and activation of p53 by ribosomal protein L23.
Molecular and cellular biology 2004;24(17):7669-80.
2004: Krishna P Bhat; Koji Itahana; Aiwen Jin; Yanping Zhang
Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation.
The EMBO journal 2004;23(12):2402-12.
2004: Yanping Zhang
The ARF-B23 connection: implications for growth control and cancer treatment.
Cell cycle (Georgetown, Tex.) 2004;3(3):259-62.
2003: Yanping Zhang; Gabrielle White Wolf; Krishna Bhat; Aiwen Jin; Theresa Allio; William A Burkhart; Yue Xiong
Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway.
Molecular and cellular biology 2003;23(23):8902-12.
2003: Koji Itahana; Krishna P Bhat; Aiwen Jin; Yoko Itahana; David Hawke; Ryuji Kobayashi; Yanping Zhang
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.
Molecular cell 2003;12(5):1151-64.
2003: Kevin O'Keefe; Huiping Li; Yanping Zhang
Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination.
Molecular and cellular biology 2003;23(18):6396-405.
2003: Nicole Schneiderhan; Andreja Budde; Yanping Zhang; Bernhard Brüne
Nitric oxide induces phosphorylation of p53 and impairs nuclear export.
Oncogene 2003;22(19):2857-68.
2002: Lawrence A Trissel; Yanping Zhang
Stability of methylprednisolone sodium succinate in autodose infusion system bags.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 2002;42(6):868-70.
2002: Lawrence A Trissel; Yanping Zhang; Mary B Baker
Stability of fenoldopam mesylate in two infusion solutions.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2002;59(9):846-8.
2001: Yanping Zhang; Lawrence A Trissel
Stability of piperacillin and ticarcillin in AutoDose infusion system bags.
The Annals of pharmacotherapy 2001;35(11):1360-3.
2001: Ming Zhao; Cynthia R Shirley; Y E Yu; Bhagyalaxmi Mohapatra; Yanping Zhang; E Unni; Jian Min Deng; Nelson A Arango; N H Terry; Michael M Weil; LD Russell; Richard R Behringer; Marvin L Meistrich
Targeted disruption of the transition protein 2 gene affects sperm chromatin structure and reduces fertility in mice.
Molecular and cellular biology 2001;21(21):7243-55.
2001: Yanping Zhang; Yue Xiong
Control of p53 ubiquitination and nuclear export by MDM2 and ARF.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(4):175-86.
2001: Yanping Zhang; Lawrence A Trissel
Compatibility of linezolid injection with intravenous administration sets.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 2001;41(2):285-6.
2000: Quanyun Xu; Yanping Zhang; Lawrence A Trissel; DL Gilbert
Adequacy of a new chlorhexidine-bearing polyurethane central venous catheter for administration of 82 selected parenteral drugs.
The Annals of pharmacotherapy 2000;34(10):1109-16.
2000: Yanping Zhang; Quanyun Xu; Lawrence A Trissel; Kimberly Y Williams
Compatibility and stability of linezolid injection admixed with three quinolone antibiotics.
The Annals of pharmacotherapy 2000;34(9):996-1001.
2000: Yanping Zhang; Quanyun Xu; Lawrence A Trissel; Kimberly Y Williams
Compatibility and stability of linezolid injection admixed with aztreonam or piperacillin sodium.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 2000;40(4):520-4.
2000: Y E Yu; Yanping Zhang; E Unni; Cynthia R Shirley; Jian Min Deng; LD Russell; Michael M Weil; Richard R Behringer; Marvin L Meistrich
Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4683-8.
1999: Q Xu; Yanping Zhang; Lawrence A Trissel
Physical and chemical stability of gemcitabine hydrochloride solutions.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 1999;39(4):509-13.
1999: Yanping Zhang; Lawrence A Trissel
Physical and chemical stability of etoposide phosphate solutions.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 1999;39(2):146-50.
1998: Quanyun Xu; Yanping Zhang; Lawrence A Trissel; DL Gilbert; JF Martinez; J L Fox
Stability of cisatracurium besylate in vials, syringes, and infusion admixtures.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1998;55(10):1037-41.
1998: Yanping Zhang; Lawrence A Trissel; JF Martinez; DL Gilbert
Stability of acyclovir sodium 1, 7, and 10 mg/mL in 5% dextrose injection and 0.9% sodium chloride injection.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1998;55(6):574-7.
1998: M Hasegawa; Yanping Zhang; H Niibe; N H Terry; Marvin L Meistrich
Resistance of differentiating spermatogonia to radiation-induced apoptosis and loss in p53-deficient mice.
Radiation research 1998;149(3):263-70.
1997: Yanping Zhang; Quanyun Xu; Lawrence A Trissel; DL Gilbert; JF Martinez
Compatibility and stability of paclitaxel combined with cisplatin and with carboplatin in infusion solutions.
The Annals of pharmacotherapy 1997;31(12):1465-70.
1997: Marvin L Meistrich; Gene Wilson; Yanping Zhang; B Kurdoglu; Nicholas H A Terry
Protection from procarbazine-induced testicular damage by hormonal pretreatment does not involve arrest of spermatogonial proliferation.
Cancer research 1997;57(6):1091-7.
1996: Quanyun Xu; Lawrence A Trissel; Yanping Zhang; JF Martinez; DL Gilbert
Stability of thiotepa (lyophilized) in 5% dextrose injection at 4 and 23 degrees C.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1996;53(22):2728-30.
1996: Yanping Zhang; Lawrence A Trissel; JF Martinez; DL Gilbert
Stability of metoclopramide hydrochloride in plastic syringes.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1996;53(11):1300-2.
1995: E Unni; Artur Mayerhofer; Yanping Zhang; Y M Bhatnagar; L D Russell; Marvin L Meistrich
Increased accessibility of the N-terminus of testis-specific histone TH2B to antibodies in elongating spermatids.
Molecular reproduction and development 1995;42(2):210-9.
1995: E Unni; Yanping Zhang; Marko Kangasniemi; W Saperstein; S B Moss; Marvin L Meistrich
Stage-specific distribution of the spermatid-specific histone 2B in the rat testis.
Biology of reproduction 1995;53(4):820-6.
1995: Robert C Millikan; B Hulka; A Thor; Yanping Zhang; Susan M Edgerton; X Zhang; H Pei; M He; L Wold; Joseph L Melton
p53 mutations in benign breast tissue.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(9):2293-300.
1994: Zahid H Siddik; G Thai; M Yoshida; Yanping Zhang; Abdul R Khokhar
Tetravalent platinum complexes with ammine/amine carrier ligand configuration: circumvention of platinum resistance in vivo.
Anti-cancer drug design 1994;9(6):495-509.
1994: E Unni; Yanping Zhang; Marvin L Meistrich; R Balhorn
Rat spermatid basic nuclear protein TP3 is the precursor of protamine 2.
Experimental cell research 1994;210(1):39-45.
1994: M Yoshida; Abdul R Khokhar; Yanping Zhang; G Thai; Zahid H Siddik
Kinetics of tissue disposition of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin in mice bearing FSaIIC tumors.
Cancer chemotherapy and pharmacology 1994;35(1):38-44.
1994: Zahid H Siddik; G Thai; M Yoshida; Yanping Zhang; Abdul R Khokhar
Ammine/amine platinum (II) complexes effective in vivo against murine tumors sensitive or resistant to cisplatin and tetraplatin.
Journal of cancer research and clinical oncology 1994;120(10):571-7.