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Zemin Zhang

Research Profile

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Computational Biology

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Chemicals & Drugs

Genes & Molecular Sequences

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Oligonucleotide Array Sequence Analysis

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Publications

TOP 3
W Yuan; Zemin Zhang; R H Soriano; E Stawiski; Howard M Stern; J J Wallin; E Chan; Steffen Durinck; K A Edgar; G Fedorowicz; F Gnad; P M Haverty; S Heldens; V Janakiraman; L Johnson; Noelyn M Kljavin; M Merchant; Zora Modrusan; C S Rivers; Meron Roose-Girma; Somasekar Seshagiri
Conditional activation of Pik3ca(H1047R) in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations.
Zemin Zhang
Genomic landscape of liver cancer.
Somasekar Seshagiri; Timothy K Starr; Eric W Stawiski; Jeremy Stinson; Elaine E Storm; Weiru Wang; Thomas D Wu; Zemin Zhang; Jeremiah D Degenhardt; Gerrit J P Dijkgraaf; Steffen Durinck; Robert Gentleman; Florian Gnad; Yinghui Guan; Joseph Guillory; Connie Ha; Peter M Haverty; Melanie A Huntley; Bijay S Jaiswal; Vasantharajan Janakiraman; Hartmut Koeppen; David A Largaespada; Zora Modrusan; Richard Bourgon; Subhra Chaudhuri; Caitlin B Conboy; Frederic J de Sauvage
Recurrent R-spondin fusions in colon cancer.

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All Publications

2013: W Yuan; Zemin Zhang; R H Soriano; E Stawiski; Howard M Stern; J J Wallin; E Chan; Steffen Durinck; K A Edgar; G Fedorowicz; F Gnad; P M Haverty; S Heldens; V Janakiraman; L Johnson; Noelyn M Kljavin; M Merchant; Zora Modrusan; C S Rivers; Meron Roose-Girma; Somasekar Seshagiri
Conditional activation of Pik3ca(H1047R) in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations.
Oncogene 2013;32(3):318-26.
2012: Zemin Zhang
Genomic landscape of liver cancer.
Nature genetics 2012;44(10):1075-7.
2012: Somasekar Seshagiri; Timothy K Starr; Eric W Stawiski; Jeremy Stinson; Elaine E Storm; Weiru Wang; Thomas D Wu; Zemin Zhang; Jeremiah D Degenhardt; Gerrit J P Dijkgraaf; Steffen Durinck; Robert Gentleman; Florian Gnad; Yinghui Guan; Joseph Guillory; Connie Ha; Peter M Haverty; Melanie A Huntley; Bijay S Jaiswal; Vasantharajan Janakiraman; Hartmut Koeppen; David A Largaespada; Zora Modrusan; Richard Bourgon; Subhra Chaudhuri; Caitlin B Conboy; Frederic J de Sauvage
Recurrent R-spondin fusions in colon cancer.
Nature 2012;488(7413):660-4.
2012: Zhaoshi Jiang; Stephanie Johnson; Adrian M Jubb; Sharookh B Kapadia; Michael I Kennemer; William Lee; Jinfeng Liu; Zora Modrusan; Krishna P Pant; Somasekar Seshagiri; Howard M Stern; Jeremy Stinson; Thomas D Wu; Weilan Ye; Stacy Yeung; Dennis G Ballinger; Paolo Carnevali; Frederic J de Sauvage; Jingyu Diao; Robert C Gentleman; Yinghui Guan; Peter M Haverty; Suchit Jhunjhunwala; Zemin Zhang
The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.
Genome research 2012;22(4):593-601.
2010: Peng Yue; William F Forrest; Joshua S Kaminker; Scott Lohr; Zemin Zhang; Guy Cavet
Inferring the functional effects of mutation through clusters of mutations in homologous proteins.
Human mutation 2010;31(3):264-71.
2009: William Lee; Peng Yue; Zemin Zhang
Analytical methods for inferring functional effects of single base pair substitutions in human cancers.
Human genetics 2009;126(4):481-98.
2009: William Lee; Yan Zhang; Kiran Mukhyala; Robert A Lazarus; Zemin Zhang
Bi-directional SIFT predicts a subset of activating mutations.
PloS one 2009;4(12):e8311.
2009: Lawrence S Hon; Yan Zhang; Joshua S Kaminker; Zemin Zhang
Computational prediction of the functional effects of amino acid substitutions in signal peptides using a model-based approach.
Human mutation 2009;30(1):99-106.
2008: Peter M Haverty; Jane Fridlyand; Li Li; Gad Getz; Rameen Beroukhim; Scott Lohr; Thomas D Wu; Guy Cavet; Zemin Zhang; Chant John
High-resolution genomic and expression analyses of copy number alterations in breast tumors.
Genes, chromosomes & cancer 2008;47(6):530-42.
2008: Jinfeng Liu; Yan Zhang; Xingye Lei; Zemin Zhang
Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective.
Genome biology 2008;9(4):R69.
2007: Yan Zhang; Shiuh-Ming Luoh; Lawrence S Hon; Robert Baertsch; William I Wood; Zemin Zhang
GeneHub-GEPIS: digital expression profiling for normal and cancer tissues based on an integrated gene database.
Nucleic acids research 2007;35(Web Server issue):W152-8.
2007: Joshua S Kaminker; Yan Zhang; Colin Watanabe; Zemin Zhang
CanPredict: a computational tool for predicting cancer-associated missense mutations.
Nucleic acids research 2007;35(Web Server issue):W595-8.
2007: Joshua S Kaminker; Yan Zhang; Allison Waugh; Peter M Haverty; Brock Peters; Dragan Sebisanovic; Jeremy Stinson; William F Forrest; J. Fernando Bazan; Somasekar Seshagiri; Zemin Zhang
Distinguishing cancer-associated missense mutations from common polymorphisms.
Cancer research 2007;67(2):465-73.
2005: Daniel Gray; Adrian M Jubb; Deborah Hogue; Patrick Dowd; Noelyn M Kljavin; Sothy Yi; Wei Bai; Gretchen D Frantz; Zemin Zhang; Hartmut Koeppen; Frederic J de Sauvage; David P Davis
Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers.
Cancer research 2005;65(21):9751-61.
2004: Yan Zhang; David A Eberhard; Gretchen D Frantz; Patrick Dowd; Thomas D Wu; Yan Zhou; Colin Watanabe; Shiuh-Ming Luoh; Paul Polakis; Kenneth J Hillan; William I Wood; Zemin Zhang
GEPIS--quantitative gene expression profiling in normal and cancer tissues.
Bioinformatics (Oxford, England) 2004;20(15):2390-8.
2004: Zemin Zhang; William J Henzel
Signal peptide prediction based on analysis of experimentally verified cleavage sites.
Protein science : a publication of the Protein Society 2004;13(10):2819-24.
2003: Yan Zhou; Shiuh-Ming Luoh; Yan Zhang; Colin Watanabe; Thomas D Wu; Michael Ostland; William I Wood; Zemin Zhang
Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis.
Cancer research 2003;63(18):5781-4.
2003: Zemin Zhang; William I Wood
A profile hidden Markov model for signal peptides generated by HMMER.
Bioinformatics (Oxford, England) 2003;19(2):307-8.
2000: Ming-Hong Xie; Sudeepta Aggarwal; W H Ho; Jessica Foster; Zemin Zhang; Jeremy Stinson; William I Wood; Audrey D Goddard; Austin Gurney
Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.
The Journal of biological chemistry 2000;275(40):31335-9.