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Wen Zhao

Research Profile

Chemicals & Drugs

Anatomy

Disorders

Myocardial Contraction

Living Beings

Phenomena

Phosphorylation

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Publications

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Chi Keung Lam; Yong Liu; Xiaoping Ren; Nathan Robbins; Jack Rubinstein; Elizabeth Vafiadaki; Zhiguo Zhang; Wen Zhao; Xiaoyang Zhou; Wenfeng Cai; Stela M Florea; Min Jiang; W Keith Jones; Evangelia G Kranias
Novel role of HAX-1 in ischemic injury protection involvement of heat shock protein 90.
Hong-Sheng Wang; Demetrios A Arvanitis; Min Dong; Paul J Niklewski; Wen Zhao; Chi Keung Lam; Evangelia G Kranias; Despina Sanoudou
SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts.
Wen Zhao; Jason R Waggoner; Zhi-Guo Zhang; Chi Keung Lam; Peidong Han; Jiang Qian; Paul M Schroder; Bryan Mitton; Aikaterini Kontrogianni-Konstantopoulos; Seth L Robia; Evangelia G Kranias
The anti-apoptotic protein HAX-1 is a regulator of cardiac function.

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All Publications

2013: Chi Keung Lam; Yong Liu; Xiaoping Ren; Nathan Robbins; Jack Rubinstein; Elizabeth Vafiadaki; Zhiguo Zhang; Wen Zhao; Xiaoyang Zhou; Wenfeng Cai; Stela M Florea; Min Jiang; W Keith Jones; Evangelia G Kranias
Novel role of HAX-1 in ischemic injury protection involvement of heat shock protein 90.
Circulation research 2013;112(1):79-89.
2011: Hong-Sheng Wang; Demetrios A Arvanitis; Min Dong; Paul J Niklewski; Wen Zhao; Chi Keung Lam; Evangelia G Kranias; Despina Sanoudou
SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts.
Physiological genomics 2011;43(7):357-64.
2009: Wen Zhao; Jason R Waggoner; Zhi-Guo Zhang; Chi Keung Lam; Peidong Han; Jiang Qian; Paul M Schroder; Bryan Mitton; Aikaterini Kontrogianni-Konstantopoulos; Seth L Robia; Evangelia G Kranias
The anti-apoptotic protein HAX-1 is a regulator of cardiac function.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(49):20776-81.
2009: Wen Zhao; Guo-Chang Fan; Zhi-Guo Zhang; Arun Bandyopadhyay; Xiaoyang Zhou; Evangelia G Kranias
Protection of peroxiredoxin II on oxidative stress-induced cardiomyocyte death and apoptosis.
Basic research in cardiology 2009;104(4):377-89.
2007: Qunying Yuan; Guo-Chang Fan; Min Dong; Beth Altschafl; Abhinav Diwan; Xiaoping Ren; Harvey H Hahn; Wen Zhao; Jason R Waggoner; Larry R Jones; W Keith Jones; Donald M Bers; Gerald W Dorn; Hong-Sheng Wang; Héctor H Valdivia; Guoxiang Chu; Evangelia G Kranias
Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity.
Circulation 2007;115(3):300-9.
2007: Guo-Chang Fan; Qunying Yuan; Wen Zhao; Guoxiang Chu; Evangelia G Kranias
Junctin is a prominent regulator of contractility in cardiomyocytes.
Biochemical and biophysical research communications 2007;352(3):617-22.
2006: Wen Zhao; Qunying Yuan; Jiang Qian; Jason R Waggoner; Anand Pathak; Guoxiang Chu; Bryan Mitton; Xiaoyin Sun; Jay Jin; Julian C Braz; Harvey S Hahn; Yehia Marreez; Faisal M Syed; Piero Pollesello; Arto Annila; Hong-Sheng Wang; Jo El J Schultz; Jeffery D Molkentin; Stephen B Liggett; Gerald W Dorn; Evangelia G Kranias
The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling.
Circulation 2006;113(7):995-1004.
2006: Yong Ji; Wen Zhao; Bailing Li; Jaime DeSantiago; Eckard Picht; Marcia A Kaetzel; Jo El J Schultz; Evangelia G Kranias; Donald M Bers; John R Dedman
Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility.
American journal of physiology. Heart and circulatory physiology 2006;290(2):H599-606.
2005: Anand Pathak; Federica del Monte; Wen Zhao; Jo-El Schultz; John N Lorenz; Ilona Bodi; Doug Weiser; Harvey Hahn; Andrew N Carr; Faisal M Syed; Nirmala Mavila; Leena Jha; Jiang Qian; Yehia Marreez; Guoli Chen; Dennis W McGraw; E Kevin Heist; J Luis Guerrero; Anna A DePaoli-Roach; Roger J Hajjar; Evangelia G Kranias
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1.
Circulation research 2005;96(7):756-66.
2004: Guo-Chang Fan; Kimberly N Gregory; Wen Zhao; Woo Jin Park; Evangelia G Kranias
Regulation of myocardial function by histidine-rich, calcium-binding protein.
American journal of physiology. Heart and circulatory physiology 2004;287(4):H1705-11.
2004: Wen Zhao; Yoshiki Uehara; Guoxiang Chu; Qiujing Song; Jiang Qian; Karen Young; Evangelia G Kranias
Threonine-17 phosphorylation of phospholamban: a key determinant of frequency-dependent increase of cardiac contractility.
Journal of molecular and cellular cardiology 2004;37(2):607-12.
2004: Guoxiang Chu; Gregory F Egnaczyk; Wen Zhao; Su-Hyun Jo; Guo-Chang Fan; John E Maggio; Rui-Ping Xiao; Evangelia G Kranias
Phosphoproteome analysis of cardiomyocytes subjected to beta-adrenergic stimulation: identification and characterization of a cardiac heat shock protein p20.
Circulation research 2004;94(2):184-93.
2003: Wen Zhao; Konrad Frank; Guoxiang Chu; Michael J Gerst; Albrecht G Schmidt; Yong Ji; Muthu Periasamy; Evangelia G Kranias
Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state.
Cardiovascular research 2003;57(1):71-81.
2001: Konrad Frank; L Mesnard-Rouiller; Guoxiang Chu; Karen B Young; Wen Zhao; Kobra Haghighi; Yoji Sato; Evangelia G Kranias
Structure and expression of the mouse cardiac calsequestrin gene.
Basic research in cardiology 2001;96(6):636-44.