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Bo-Jian Zheng

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Anna J X Zhang; Bo-Jian Zheng; Chris C S Chan; Ivan F N Hung; Karen S L Lam; Candy C Y Lau; Can Li; Vincent K M Poon; Kelvin K W To; Aimin Xu; Kwok yung Yuen
Leptin mediates the pathogenesis of severe 2009 pandemic influenza A(H1N1) infection associated with cytokine dysregulation in mice with diet-induced obesity.
Lanying Du; Lei Jin; Junfeng Li; Ye Li; Robert C Liddington; Shihui Sun; Hong Yu; Guangyu Zhao; Bo-Jian Zheng; Yusen Zhou; Shibo Jiang
Identification and structural characterization of a broadly neutralizing antibody targeting a novel conserved epitope on the influenza virus H5N1 hemagglutinin.
Susanna K P Lau; Kang-Sheng Li; Rosana W S Poon; Chung-Tong Shek; Alan K L Tsang; Ming Wang; Sylvia Y H Wang; Beatrice H L Wong; Patrick C Y Woo; Kwok-Hung Chan; Garnet K Y Choi; Rachel Y Y Fan; Rongtong Guo; Carol S F Lam; Bo-Jian Zheng; Kwok-Yung Yuen
Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders.

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2013: Anna J X Zhang; Bo-Jian Zheng; Chris C S Chan; Ivan F N Hung; Karen S L Lam; Candy C Y Lau; Can Li; Vincent K M Poon; Kelvin K W To; Aimin Xu; Kwok yung Yuen
Leptin mediates the pathogenesis of severe 2009 pandemic influenza A(H1N1) infection associated with cytokine dysregulation in mice with diet-induced obesity.
The Journal of infectious diseases 2013;207(8):1270-80.
2013: Lanying Du; Lei Jin; Junfeng Li; Ye Li; Robert C Liddington; Shihui Sun; Hong Yu; Guangyu Zhao; Bo-Jian Zheng; Yusen Zhou; Shibo Jiang
Identification and structural characterization of a broadly neutralizing antibody targeting a novel conserved epitope on the influenza virus H5N1 hemagglutinin.
Journal of virology 2013;87(4):2215-25.
2012: Susanna K P Lau; Kang-Sheng Li; Rosana W S Poon; Chung-Tong Shek; Alan K L Tsang; Ming Wang; Sylvia Y H Wang; Beatrice H L Wong; Patrick C Y Woo; Kwok-Hung Chan; Garnet K Y Choi; Rachel Y Y Fan; Rongtong Guo; Carol S F Lam; Bo-Jian Zheng; Kwok-Yung Yuen
Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders.
Journal of virology 2012;86(21):11906-18.
2012: Jie Zhou; Guo-Ping Zhao; Bo-Jian Zheng; Kwok-Hung Chan; Zhong-Shan Cheng; Hui Dong; Yan-Hui Fan; Candy Choi-Yi Lau; Vincent K M Poon; You-Qiang Song; Kelvin Kai-Wang To; Herman Tse; Kwok-Yung Yuen
A functional variation in CD55 increases the severity of 2009 pandemic H1N1 influenza A virus infection.
The Journal of infectious diseases 2012;206(4):495-503.
2012: Liang Hu; Ke-Ke Huo; Ming Liu; Jian Wang; Dan Xie; Bo-Jian Zheng; Tim Hon Man Chan; Leilei Chen; Xin-Yuan Guan
SCYL1 binding protein 1 promotes the ubiquitin-dependent degradation of Pirh2 and has tumor-suppressive function in the development of hepatocellular carcinoma.
Carcinogenesis 2012;33(8):1581-8.
2012: Susanna K P Lau; Alan K L Tsang; Ming Wang; Patrick C Y Woo; Cyril C Y Yip; Kwok-Hung Chan; Xiao-Yan Che; Rachel Y Y Fan; Rongtong Guo; Yi Huang; Kenneth Lai; Carol S F Lam; Bo-Jian Zheng; Kwok-Yung Yuen
Isolation and characterization of a novel Betacoronavirus subgroup A coronavirus, rabbit coronavirus HKU14, from domestic rabbits.
Journal of virology 2012;86(10):5481-96.
2012: Patrick C Y Woo; Ying Wu; Anna J X Zhang; Bo-Jian Zheng; Kwok-Hung Chan; Garnet K Y Choi; Rachel Y Y Fan; Janet Hui; Susanna K P Lau; Kang-Sheng Li; Ming Wang; Annette Y P Wong; Beatrice H L Wong; Kwok-Yung Yuen
Feline morbillivirus, a previously undescribed paramyxovirus associated with tubulointerstitial nephritis in domestic cats.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(14):5435-40.
2012: Patrick C Y Woo; Bo-Jian Zheng; Ru Bai; Kwok-Hung Chan; Carol S F Lam; Candy C Y Lau; John H N Lau; Susanna K P Lau; Jade L L Teng; Alan K L Tsang; Chris C C Tsang; Ming Wang; Kwok-Yung Yuen
Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus.
Journal of virology 2012;86(7):3995-4008.
2012: Ting Lei; Patrick C K Li; Kam-Leung Siu; Kelvin K W To; Ming Wang; Kwok-Yung Yuen; Bo-Jian Zheng; Jie Zhou; Eric Y T Chan; Kwok-Hung Chan; I F N Hung; Kin-Hang Kok; Dong-Yan Jin
Anti-ganglioside antibodies were not detected in human subjects infected with or vaccinated against 2009 pandemic influenza A (H1N1) virus.
Vaccine 2012;30(16):2605-10.
2012: Tim Hon Man Chan; Leilei Chen; Liang Hu; Jian-Dong Huang; Pinzhu Huang; Ming Liu; Vincent Kwok-Man Poon; George Sai-wah Tsao; Jie Yang; Yun-Fei Yuan; Bo-Jian Zheng; Xin-Yuan Guan
Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development.
Hepatology (Baltimore, Md.) 2012;55(2):491-505.
2012: Song-yue Zheng; Min Chen; Yan-Hong Hua; Rory Munro Watt; Bin Yu; Shuofeng Yuan; Kwok-Yung Yuen; Ke Zhang; Bo-Jian Zheng; Jian-Dong Huang
Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines.
BMC immunology 2012;13():54.
2012: Lin Xu; Kwok-Yung Yuen; Ding-mei Zhang; Bo-Jian Zheng; Rong Zhou; Fa-shen Feng; Lin-lin Guan; Xia He; Meng-feng Li; Zhu Wang; Jue-heng Wu; Kai-Yuan Cao
Surveillance and genome analysis of human bocavirus in patients with respiratory infection in Guangzhou, China.
PloS one 2012;7(9):e44876.
2012: Hao Wu; Hui-fang Xu; Hao-Jie Zhang; Xiao-min Zhang; Jian-Dong Huang; Ming Wang; Bo-Jian Zheng
Identification of drug resistant mutations in HIV-1 CRF07_BC variants selected by nevirapine in vitro.
PloS one 2012;7(9):e44333.
2012: Bin Yu; Kwok-Yung Yuen; Bo-Jian Zheng; Qinqin Jiang; Xuefei Li; Lei Shi; David K Smith; Erwei Song; Lei-Han Tang; Mei Yang; Yandan Yao; Jian-Dong Huang
Explicit hypoxia targeting with tumor suppression by creating an "obligate" anaerobic Salmonella Typhimurium strain.
Scientific reports 2012;2():436.
2012: Qiwei Zhang; Xiaomin Zhang; Zhiwei Chen; Donald Seto; Chengsong Wan; Hao Wu; Hao-Jie Zhang; Bo-Jian Zheng
Parental LTRs are important in a construct of a stable and efficient replication-competent infectious molecular clone of HIV-1 CRF08_BC.
PloS one 2012;7(2):e31233.
2011: Xiaohui Wang; Min Yang; Kwok Yung Yuen; Bo-Jian Zheng; Jie Zhou; Chris C S Chan; Jun Deng; King-Hung Ko; Virtual H C Leung; Vincent K M Poon; Liwei Lu
A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection.
Cellular & molecular immunology 2011;8(6):462-8.
2011: Bin Yu; Kwok-Yung Yuen; Bo-Jian Zheng; Erwei Song; Rory Munro Watt; Ho Yin Bosco Wong; Mei Yang; Jian-Dong Huang
A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategy.
Applied microbiology and biotechnology 2011;91(1):177-88.
2011: Leilei Chen; Yun-Fei Yuan; Yan Li; Tim Hon Man Chan; Bo-Jian Zheng; Jun Huang; Xin-Yuan Guan
Clinical significance of CHD1L in hepatocellular carcinoma and therapeutic potentials of virus-mediated CHD1L depletion.
Gut 2011;60(4):534-43.
2011: Tiegang Li; Enjie Lu; Jianyun Lu; Yulin Wang; Jibin Wu; Zhicong Yang; Bo-Jian Zheng; Kai-Yuan Cao; Yiyun Chen; Biao Di; Zhiqiang Dong; Chuanxi Fu; Jinmei Geng; Wensui Hu; Meixia Li; Meng-Feng Li; Ming Wang
A two-year surveillance of 2009 pandemic influenza A (H1N1) in Guangzhou, China: from pandemic to seasonal influenza?
PloS one 2011;6(11):e28027.
2011: Herman Tse; Hoi-Wah Tsoi; Patrick C Y Woo; Xin-Chun Chen; Susanna K P Lau; Haiying Liu; Jade L L Teng; Bo-Jian Zheng; Boping Zhou; Kwok-Yung Yuen
Discovery and genomic characterization of a novel ovine partetravirus and a new genotype of bovine partetravirus.
PloS one 2011;6(9):e25619.
2011: Lanying Du; Virtual Ho-Chuen Leung; Xiujuan Zhang; Jie Zhou; Min Chen; Wu He; Hai-Ying Zhang; Chris C S Chan; Vincent K M Poon; Guangyu Zhao; Shihui Sun; Lifeng Cai; Yusen Zhou; Bo-Jian Zheng; Shibo Jiang
A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses.
PloS one 2011;6(1):e16555.
2011: Zai Wang; Jian-Dong Huang; Kin-Ling Wong; Pei-Gang Wang; Hao-Jie Zhang; Julian Tanner; ottavia spiga; Andrea Bernini; Bo-Jian Zheng; Neri Niccolai
On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus.
The FEBS journal 2011;278(2):383-9.
2011: Ke Xu; Christoph Klenk; Bin Liu; Bjoern Keiner; Jinke Cheng; Bo-Jian Zheng; Li Li; Qinglin Han; Chen Wang; Tianxian Li; Ze Chen; Yuelong Shu; Jinhua Liu; Hans-Dieter Klenk; Bing Sun
Modification of nonstructural protein 1 of influenza A virus by SUMO1.
Journal of virology 2011;85(2):1086-98.
2010: Stephanie Ma; Kwan Ho Tang; Yuen-Piu Chan; Terence K Lee; Pak Shing Kwan; Antonia Castilho; Irene Ng; Kwan Man; Nathalie Wong; Ka-Fai To; Bo-Jian Zheng; Paul B S Lai; Chung-Mau Lo; Kwok Wah Chan; Xin-Yuan Guan
miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.
Cell stem cell 2010;7(6):694-707.
2010: Susanna K P Lau; Rosana W S Poon; Beatrice H L Wong; Ming Wang; Yi Huang; Huifang Xu; Rongtong Guo; Kang-Sheng Li; Kai Gao; Kwok-Hung Chan; Bo-Jian Zheng; Patrick C Y Woo; Kwok-Yung Yuen
Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup.
Journal of virology 2010;84(21):11385-94.
2010: Guangyu Zhao; Lanying Du; Wenjun Xiao; Shihui Sun; Yongping Lin; Min Chen; Zhihua Kou; Yuxian He; Sara Lustigman; Shibo Jiang; Bo-Jian Zheng; Yusen Zhou
Induction of protection against divergent H5N1 influenza viruses using a recombinant fusion protein linking influenza M2e to Onchocerca volvulus activation associated protein-1 (ASP-1) adjuvant.
Vaccine 2010;28(44):7233-40.
2010: Susanna K P Lau; Patrick C Y Woo; Beatrice H L Wong; Annette Y P Wong; Hoi-Wah Tsoi; Ming Wang; Paul Lee; Huifang Xu; Rosana W S Poon; Rongtong Guo; Kang-Sheng Li; Kwok-Hung Chan; Bo-Jian Zheng; Kwok-Yung Yuen
Identification and complete genome analysis of three novel paramyxoviruses, Tuhoko virus 1, 2 and 3, in fruit bats from China.
Virology 2010;404(1):106-16.
2010: Lanying Du; Guangyu Zhao; Xiujuan Zhang; Zhonghua Liu; Hong Yu; Bo-Jian Zheng; Yusen Zhou; Shibo Jiang
Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies.
Biochemical and biophysical research communications 2010;397(3):580-5.
2010: Richard Y T Kao; Dan Yang; Lai-Shan Lau; Wayne H W Tsui; Lihong Hu; Jun Dai; Mei-Po Chan; Che-Man Chan; Pui Wang; Bo-Jian Zheng; Jian Sun; Jian-Dong Huang; Jason Madar; Guanhua Chen; Honglin Chen; Yi Guan; Kwok-Yung Yuen
Identification of influenza A nucleoprotein as an antiviral target.
Nature biotechnology 2010;28(6):600-5.
2010: Lanying Du; Guangyu Zhao; Chris C S Chan; Lin Li; Yuxian He; Yusen Zhou; Bo-Jian Zheng; Shibo Jiang
A 219-mer CHO-expressing receptor-binding domain of SARS-CoV S protein induces potent immune responses and protective immunity.
Viral immunology 2010;23(2):211-9.
2010: Min Yang; Lingyun Sun; Shengjun Wang; King-Hung Ko; Huaxi Xu; Bo-Jian Zheng; Xuetao Cao; Liwei Lu
Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(7):3321-5.
2010: Ding-Qiang Chen; Yong Zeng; Jie Zhou; Ling Yang; Shibo Jiang; Jian-Dong Huang; Liwei Lu; Bo-Jian Zheng
Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population.
Journal of medical virology 2010;82(3):371-8.
2010: Susanna K P Lau; Kang-Sheng Li; Yi Huang; Chung-Tong Shek; Herman Tse; Ming Wang; Garnet K Y Choi; Huifang Xu; Carol S F Lam; Rongtong Guo; Kwok-Hung Chan; Bo-Jian Zheng; Patrick C Y Woo; Kwok-Yung Yuen
Ecoepidemiology and complete genome comparison of different strains of severe acute respiratory syndrome-related Rhinolophus bat coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events.
Journal of virology 2010;84(6):2808-19.
2010: Kwok-Hung Chan; Anna J X Zhang; Kelvin K W To; Chris C S Chan; Vincent K M Poon; Kunyuan Guo; Fai Ng; Qi-Wei Zhang; Virtual H C Leung; Annie N Y Cheung; Candy C Y Lau; Patrick C Y Woo; Herman Tse; Wailan Wu; Honglin Chen; Bo-Jian Zheng; Kwok-Yung Yuen
Wild type and mutant 2009 pandemic influenza A (H1N1) viruses cause more severe disease and higher mortality in pregnant BALB/c mice.
PloS one 2010;5(10):e13757.
2010: Guangyu Zhao; Shihui Sun; Lanying Du; Wenjun Xiao; Zhitao Ru; Zhihua Kou; Yan Guo; Hong Yu; Shibo Jiang; Yuchun Lone; Bo-Jian Zheng; Yusen Zhou
An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virus.
Virology journal 2010;7():151.
2010: Yan Li; Jin-kou Zhao; Ming Wang; Zhi-Gang Han; Wei-Ping Cai; Bo-Jian Zheng; Hui-Fang Xu
Current antibody-based immunoassay algorithm failed to confirm three late-stage AIDS cases in China: case report.
Virology journal 2010;7():58.
2010: Guangyu Zhao; Yongping Lin; Lanying Du; Jie Guan; Shihui Sun; Hongyan Sui; Zhihua Kou; Chris Cs Chan; Yan Guo; Shibo Jiang; Bo-Jian Zheng; Yusen Zhou
An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses.
Virology journal 2010;7():9.
2009: I W S Li; Kwok-Hung Chan; K W K To; S S Y Wong; Pak-Leung Ho; S K P Lau; P C Y Woo; Hoi-Wah Tsoi; J F W Chan; V C C Cheng; Bo-Jian Zheng; Honglin Chen; Kwok-Yung Yuen
Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2009;46(4):325-30.
2009: Lanying Du; Guangyu Zhao; Chris C S Chan; Shihui Sun; Min Chen; Zhonghua Liu; Hongxiang Guo; Yuxian He; Yusen Zhou; Bo-Jian Zheng; Shibo Jiang
Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity.
Virology 2009;393(1):144-50.
2009: Cherry Kam Chun Lo; Queenie Lai Kwan Lam; Min Yang; King-Hung Ko; Lingyun Sun; Rui Ma; Shengjun Wang; Huaxi Xu; Sidney Tam; Chang-You Wu; Bo-Jian Zheng; Liwei Lu
Leptin signaling protects NK cells from apoptosis during development in mouse bone marrow.
Cellular & molecular immunology 2009;6(5):353-60.
2009: Kam-Leung Siu; Cangel Pui-Yee Chan; Chris Chan; Bo-Jian Zheng; Dong-Yan Jin
Severe acute respiratory syndrome coronavirus nucleocapsid protein does not modulate transcription of the human FGL2 gene.
The Journal of general virology 2009;90(Pt 9):2107-13.
2009: Jie Zhou; Jian-Dong Huang; Vincent K M Poon; Ding-Qiang Chen; Chris C S Chan; Fai Ng; Xin-Yuan Guan; Rory Munro Watt; Liwei Lu; Kwok-Yung Yuen; Bo-Jian Zheng
Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection.
Journal of hepatology 2009;51(2):322-32.
2009: Lanying Du; Guangyu Zhao; Lin Li; Yuxian He; Yusen Zhou; Bo-Jian Zheng; Shibo Jiang
Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells.
Biochemical and biophysical research communications 2009;384(4):486-90.
2009: Leilei Chen; Liang Hu; Tak Hang Chan; George S W Tsao; Dan Xie; Ke-Ke Huo; Li Fu; Stephanie Ma; Bo-Jian Zheng; Xin-Yuan Guan
Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.
Hepatology (Baltimore, Md.) 2009;50(1):122-9.
2009: Kam-Leung Siu; Kin-Hang Kok; Ming-Him James Ng; Vincent K M Poon; Kwok-Yung Yuen; Bo-Jian Zheng; Dong-Yan Jin
Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.
The Journal of biological chemistry 2009;284(24):16202-9.
2009: Ming Wang; Chuanxi Fu; Bo-Jian Zheng
Antibodies against H5 and H9 avian influenza among poultry workers in China.
The New England journal of medicine 2009;360(24):2583-4.
2009: Ke Xu; Bo-Jian Zheng; Rong Zeng; Wei Lu; Yong-Ping Lin; Liang Xue; Li Li; Lei-Lei Yang; Chen Xu; Jie Dai; Fei Wang; Qing Li; Qing-Xi Dong; Ruifu Yang; Jia-Rui Wu; Bing Sun
Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein.
Virology 2009;388(2):279-85.
2009: Xiu-Ying Zhao; Rui-Shan Li; Jia-Qing Huang; Zhi-Wei Chen; Bo-Jian Zheng
[A transcriptional study of SDF-1alpha expression in PBL and the correlation between SDF-1alpha transcription and HIV-1 infection].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2009;23(3):204-7.
2009: Ming-Liang He; Bo-Jian Zheng; Ying Chen; Kin-Ling Wong; Jian-Dong Huang; Marie C M Lin; Kwok-Yung Yuen; J J Y Sung; Hsiang-Fu Kung
Development of interfering RNA agents to inhibit SARS-associated coronavirus infection and replication.
Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 2009;15(3 Suppl 4):28-31.
2009: Jie Zhou; Ding-Qiang Chen; Vincent K M Poon; Yong Zeng; Fai Ng; Liwei Lu; Jian-Dong Huang; Kwok-Yung Yuen; Bo-Jian Zheng
A regulatory polymorphism in interferon-gamma receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection.
Immunogenetics 2009;61(6):423-30.
2009: Che-Man Chan; Herman Tse; S S Y Wong; P C Y Woo; S K P Lau; L Chen; Bo-Jian Zheng; Jian-Dong Huang; Kwok-Yung Yuen
Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2009;45(1):54-60.
2009: Lanying Du; Yuxian He; Yusen Zhou; Shuwen Liu; Bo-Jian Zheng; Shibo Jiang
The spike protein of SARS-CoV--a target for vaccine and therapeutic development.
Nature reviews. Microbiology 2009;7(3):226-36.
2009: Qiwei Zhang; Xiaobo Su; Donald Seto; Bo-Jian Zheng; Xingui Tian; Huiying Sheng; Haitao Li; Youshao Wang; Rong Zhou
Construction and characterization of a replication-competent human adenovirus type 3-based vector as a live-vaccine candidate and a viral delivery vector.
Vaccine 2009;27(8):1145-53.
2009: Dong-Yan Jin; Bo-Jian Zheng
Roles of spike protein in the pathogenesis of SARS coronavirus.
Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 2009;15 Suppl 2():37-40.
2009: Zhi Li; Ming-Liang He; Hong Yao; Qing-Ming Dong; Yang-Chao Chen; Chu-Yan Chan; Bo-Jian Zheng; Kwok-Yung Yuen; Ying Peng; Qiang Sun; Xiao Yang; Marie C Lin; Joseph J Y Sung; Hsiang-Fu Kung
Inhibition of HBV replication and gene expression in vitro and in vivo with a single AAV vector delivering two shRNA molecules.
BMB reports 2009;42(1):59-64.
2009: Muhan Chen; Jian-Dong Huang; Liang Hu; Bo-Jian Zheng; Leilei Chen; Sze Lan Tsang; Xin-yuan Guan
Transgenic CHD1L expression in mouse induces spontaneous tumors.
PloS one 2009;4(8):e6727.
2009: Hao-Jie Zhang; Yong-Xiang Wang; Hao Wu; Dong-Yan Jin; Yu-Mei Wen; Bo-Jian Zheng
The y271 and i274 amino acids in reverse transcriptase of human immunodeficiency virus-1 are critical to protein stability.
PloS one 2009;4(7):e6108.
2009: Hong-Yan Sui; Guang-Yu Zhao; Jian-Dong Huang; Dong-Yan Jin; Kwok-Yung Yuen; Bo-Jian Zheng
Small interfering RNA targeting m2 gene induces effective and long term inhibition of influenza A virus replication.
PloS one 2009;4(5):e5671.
2009: Jin-Yan Chen; Wan-Nan Chen; Kwok-Man Vincent Poon; Bo-Jian Zheng; Xu Lin; Yong-Xiang Wang; Yu-Mei Wen
Interaction between SARS-CoV helicase and a multifunctional cellular protein (Ddx5) revealed by yeast and mammalian cell two-hybrid systems.
Archives of virology 2009;154(3):507-12.
2009: Che-Man Chan; Susanna K P Lau; Patrick C Y Woo; Herman Tse; Bo-Jian Zheng; Ling Chen; Jian-Dong Huang; Kwok-Yung Yuen
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection.
Journal of virology 2009;83(2):1026-35.
2009: Jie Zhou; D K Smith; Liwei Lu; V K M Poon; F Ng; D-Q Chen; J-D Huang; K-Y Yuen; Kai-Yuan Cao; Bo-Jian Zheng
A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection.
Journal of viral hepatitis 2009;16(1):45-52.
2008: Yong-Xiang Wang; Hao-Jie Zhang; Jing Xu; Bo-Jian Zheng; Yu-Mei Wen
Mutational analysis of the "turn" of helix clamp motif of HIV-1 reverse transcriptase.
Biochemical and biophysical research communications 2008;377(3):915-20.
2008: Che-Man Chan; Patrick C Y Woo; Susanna K P Lau; Herman Tse; Hong-Lin Chen; Feng Li; Bo-Jian Zheng; Ling Chen; Jian-Dong Huang; Kwok-Yung Yuen
Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection.
Experimental biology and medicine (Maywood, N.J.) 2008;233(12):1527-36.
2008: Queenie Lai Kwan Lam; Otis King Hung Ko; Bo-Jian Zheng; Liwei Lu
Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):14993-8.
2008: Cherry Kam Chun Lo; Queenie Lai Kwan Lam; Lingyun Sun; Shengjun Wang; King-Hung Ko; Huaxi Xu; Chang-You Wu; Bo-Jian Zheng; Liwei Lu
Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production.
Arthritis and rheumatism 2008;58(9):2700-11.
2008: Bo-Jian Zheng; L Y Du; G Y Zhao; Y P Lin; H Y Sui; C Chan; S Ma; Yi Guan; Kwok-Yung Yuen
Studies of SARS virus vaccines.
Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 2008;14 Suppl 4():39-43.
2008: J D Huang; Bo-Jian Zheng; Hong-Zhe Sun
Helicases as antiviral drug targets.
Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 2008;14 Suppl 4():36-8.
2008: Susanna K P Lau; Patrick C Y Woo; Herman Tse; Clara T Y Fu; Wing-Ka Au; Xin-Chun Chen; Hoi-Wah Tsoi; Thomas H F Tsang; Joanna S Y Chan; Dominic N C Tsang; Kang-Sheng Li; Cindy W S Tse; Tak-Keung Ng; Owen T Y Tsang; Bo-Jian Zheng; Sidney Tam; Kwok-Hung Chan; Boping Zhou; Kwok-Yung Yuen
Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4.
The Journal of general virology 2008;89(Pt 8):1840-8.
2008: Stephanie Ma; Kwok Wah Chan; Terence Kin-Wah Lee; Kwan Ho Tang; Jana Yim-Hung Wo; Bo-Jian Zheng; Xin-Yuan Guan
Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.
Molecular cancer research : MCR 2008;6(7):1146-53.
2008: Bo-Jian Zheng; Kwok Wah Chan; Yong-Ping Lin; Guang-Yu Zhao; Chris Chan; Hao-Jie Zhang; Hong-Lin Chen; Samson S Y Wong; Susanna K P Lau; Patrick C Y Woo; Kwok-Hung Chan; Dong-Yan Jin; Kwok-Yung Yuen
Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(23):8091-6.
2008: Zhi Li; Hong Yao; Yan Ma; Qingming Dong; Yangchao Chen; Ying Peng; Bo-Jian Zheng; Jian-Dong Huang; Chu-yan Chan; Marie C Lin; Joseph J Sung; Kwok Yun Yuen; Hsiang-Fu Kung; Ming-Liang He
Inhibition of HBV gene expression and replication by stably expressed interferon-alpha1 via adeno-associated viral vectors.
The journal of gene medicine 2008;10(6):619-27.
2008: Lanying Du; Guangyu Zhao; Yongping Lin; Chris Chan; Yuxian He; Shibo Jiang; Changyou Wu; Dong-Yan Jin; Kwok-Yung Yuen; Yusen Zhou; Bo-Jian Zheng
Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection.
Vaccine 2008;26(13):1644-51.
2008: Ning-Fang Ma; Liang Hu; Jackie M Fung; Dan Xie; Bo-Jian Zheng; Leilei Chen; Dong-Jiang Tang; Li Fu; Zhenguo Wu; Muhan Chen; Yan Fang; Xin-Yuan Guan
Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2008;47(2):503-10.
2008: Lanying Du; Guangyu Zhao; Yongping Lin; Hongyan Sui; Chris Chan; Selene Ma; Yuxian He; Shibo Jiang; Changyou Wu; Kwok-Yung Yuen; Dong-Yan Jin; Yusen Zhou; Bo-Jian Zheng
Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong mucosal immune responses and provides long-term protection against SARS-CoV infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):948-56.
2008: Lanying Du; Yuxian He; Shibo Jiang; Bo-Jian Zheng
Development of subunit vaccines against severe acute respiratory syndrome.
Drugs of today (Barcelona, Spain : 1998) 2008;44(1):63-73.
2007: Kai-Yuan Cao; Xiao-Peng Mao; Dao-Hu Wang; Lin Xu; Guang-Qing Yuan; Shu-Qin Dai; Bo-Jian Zheng; Shao-peng Qiu
High expression of PSM-E correlated with tumor grade in prostate cancer: a new alternatively spliced variant of prostate-specific membrane antigen.
The Prostate 2007;67(16):1791-800.
2007: Nan Yang; Julian Tanner; Zai Wang; Jian-Dong Huang; Bo-Jian Zheng; Nianyong Zhu; Hongzhe Sun
Inhibition of SARS coronavirus helicase by bismuth complexes.
Chemical communications (Cambridge, England) 2007;(42):4413-5.
2007: Susanna K P Lau; Patrick C Y Woo; Kang-Sheng Li; Yi Huang; Ming Wang; Carol S F Lam; Huifang Xu; Rongtong Guo; Kwok-Hung Chan; Bo-Jian Zheng; Kwok-Yung Yuen
Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome.
Virology 2007;367(2):428-39.
2007: Queenie Lai Kwan Lam; Bo-Jian Zheng; Dong-Yan Jin; Xuetao Cao; Liwei Lu
Leptin induces CD40 expression through the activation of Akt in murine dendritic cells.
The Journal of biological chemistry 2007;282(38):27587-97.
2007: Lanying Du; Richard Y T Kao; Yusen Zhou; Yuxian He; Guangyu Zhao; Charlotte Wong; Shibo Jiang; Kwok-Yung Yuen; Dong-Yan Jin; Bo-Jian Zheng
Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity.
Biochemical and biophysical research communications 2007;359(1):174-9.
2007: Stephanie Ma; Kwok Wah Chan; Liang Hu; Terence K Lee; Jana Yim-Hung Wo; Irene Oi-Lin Ng; Bo-Jian Zheng; Xin-Yuan Guan
Identification and characterization of tumorigenic liver cancer stem/progenitor cells.
Gastroenterology 2007;132(7):2542-56.
2007: Jonathan Chen; KH Wong; K Chan; HY Lam; S S Lee; P Li; M P Lee; Dominic N C Tsang; Bo-Jian Zheng; Kwok-Yung Yuen; Wing-Cheong Yam
Evaluation of an in-house genotyping resistance test for HIV-1 drug resistance interpretation and genotyping.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007;39(2):125-31.
2007: Lanying Du; Guangyu Zhao; Yuxian He; Yan Guo; Bo-Jian Zheng; Shibo Jiang; Yusen Zhou
Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model.
Vaccine 2007;25(15):2832-8.
2007: Man-Fung Yuen; Danny Ka-Ho Wong; Bo-Jian Zheng; C C-S Chan; John Chi-Hang Yuen; Benjamin Chun-Yu Wong; Ching-Lung Lai
Difference in T helper responses during hepatitis flares in hepatitis B e antigen (HBeAg)-positive patients with genotypes B and C: implication for early HBeAg seroconversion.
Journal of viral hepatitis 2007;14(4):269-75.
2007: Queenie Lai Kwan Lam; Cherry Kam Chun Lo; Bo-Jian Zheng; King-Hung Ko; Dennis G Osmond; Gillian E Wu; Robert Rottapel; Liwei Lu
Impaired V(D)J recombination and increased apoptosis among B cell precursors in the bone marrow of c-Abl-deficient mice.
International immunology 2007;19(3):267-76.
2007: Jie Zhou; Liwei Lu; Man-Fung Yuen; Ting Wa Lam; Chi-Ping Chung; Chun-Lit Lam; Bin Zhang; Song Wang; Yu Chen; Sharon H W Wu; Vincent K M Poon; Fai Ng; Chris C S Chan; Shibo Jiang; Kwok-Yung Yuen; Bo-Jian Zheng
Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection.
Journal of hepatology 2007;46(2):198-205.
2007: Patrick C Y Woo; Ming Wang; Susanna K P Lau; Huifang Xu; Rosana W S Poon; Rongtong Guo; Beatrice H L Wong; Kai Gao; Hoi-Wah Tsoi; Yi Huang; Kang-Sheng Li; Carol S F Lam; Kwok-Hung Chan; Bo-Jian Zheng; Kwok-Yung Yuen
Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features.
Journal of virology 2007;81(4):1574-85.
2007: Nan Yang; Julian Tanner; Bo-Jian Zheng; Rory Munro Watt; Ming-Liang He; Lin-Yu Lu; Jie-Qing Jiang; Ka-To Shum; Yong-Ping Lin; Kin-Ling Wong; Marie C M Lin; Hsiang-Fu Kung; Hongzhe Sun; Jian-Dong Huang
Bismuth complexes inhibit the SARS coronavirus.
Angewandte Chemie (International ed. in English) 2007;46(34):6464-8.
2006: Ming Wang; Biao Di; Duan-hua Zhou; Bo-Jian Zheng; Huaiqi Jing; Yong-Ping Lin; Yu-fei Liu; Xin-wei Wu; Peng-Zhe Qin; Yu-Lin Wang; Li-Yun Jian; Xiang-Zhong Li; Jian-Xiong Xu; En-jie Lu; Tie-Gang Li; Jianguo Xu
Food markets with live birds as source of avian influenza.
Emerging infectious diseases 2006;12(11):1773-5.
2006: Lanying Du; Yuxian He; Yijia Wang; Haojie Zhang; Selene Ma; Charlotte K L Wong; Sharon H W Wu; Fai Ng; Jian-Dong Huang; Kwok-Yung Yuen; Shibo Jiang; Yusen Zhou; Bo-Jian Zheng
Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines.
Virology 2006;353(1):6-16.
2006: Ying Zheng; Kai-Yuan Cao; Sze Park Ng; Daniel T T Chua; Jonathan S T Sham; Dora L W Kwong; Mun-Hon Ng; Liwei Lu; Bo-Jian Zheng
Complementary activation of peripheral natural killer cell immunity in nasopharyngeal carcinoma.
Cancer science 2006;97(9):912-9.
2006: Cangel Pui-Yee Chan; Junet W Y Choi; Kai-Yuan Cao; Ming Wang; Yang Gao; Duan-hua Zhou; Biao Di; Hui-fang Xu; Man-Fai Leung; Andreas Bergmann; Matthias Lehmann; Yong-Mei Nie; George W H Cautherley; Dietmar Fuchs; Reinhard Renneberg; Bo-Jian Zheng
Detection of serum neopterin for early assessment of dengue virus infection.
The Journal of infection 2006;53(3):152-8.
2006: Wei Lu; Bo-Jian Zheng; Ke Xu; Wolfgang Schwarz; Lanying Du; Charlotte K L Wong; Jiadong Chen; Shuming Duan; Vincent Deubel; Bing Sun
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12540-5.
2006: Ming-Liang He; Bo-Jian Zheng; Ying Chen; Kin-Ling Wong; Jian-Dong Huang; Marie C Lin; Ying Peng; Kwok Y Yuen; Joseph J Y Sung; Hsiang-Fu Kung
Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus.
FEBS letters 2006;580(10):2414-20.
2006: Wing-Cheong Yam; Jonathan Chen; KH Wong; K Chan; V C C Cheng; HY Lam; S S Lee; Bo-Jian Zheng; Kwok-Yung Yuen
Clinical utility of genotyping resistance test on determining the mutation patterns in HIV-1 CRF01_AE and subtype B patients receiving antiretroviral therapy in Hong Kong.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006;35(4):454-7.
2005: Bao-jian Li; Qingquan Tang; Du Cheng; Chuan Qin; Frank Y Xie; Qiang Wei; Jun Xu; Yijia Liu; Bo-Jian Zheng; Martin C Woodle; Nanshan Zhong; Patrick Y Lu
Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque.
Nature medicine 2005;11(9):944-51.
2005: Zhong-ping Duan; Xiu-ying Zhao; De-zhuang Huang; Li-xiang He; Yu Chen; Chun-hui Zhao; Bo-Jian Zheng
RANTES gene single nucleotide polymorphisms and expression in patients with chronic hepatitis B virus infection.
Chinese medical journal 2005;118(11):909-14.
2005: Xiu-Ying Zhao; Shui-Shan Lee; Ka-Hing Wong; Kenny Chi-Wai Chan; Fai Ng; Chris C S Chan; Dan Han; Wing-Cheong Yam; Kwok-Yung Yuen; Mun-Hon Ng; Bo-Jian Zheng
Functional analysis of naturally occurring mutations in the open reading frame of CCR5 in HIV-infected Chinese patients and healthy controls.
Journal of acquired immune deficiency syndromes (1999) 2005;38(5):509-17.
2005: Julian Tanner; Bo-Jian Zheng; Jie Zhou; Rory Munro Watt; Jie-Qing Jiang; Kin-Ling Wong; Yong-Ping Lin; Lin-Yu Lu; Ming-Liang He; Hsiang-Fu Kung; Andreas J Kesel; Jian-Dong Huang
The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus.
Chemistry & biology 2005;12(3):303-11.
2005: Ming Wang; Yang Gao; Duan-hua Zhou; Xin-wei Wu; Xiao-shuang Chen; Biao Di; Yu-fei Liu; Fang Chen; Lin Du; Hui-fang Xu; Jing Gu; Bo-Jian Zheng; Jian-guo Xu
[The effects of 4 laboratory test kits in early detecting of severe acute respiratory syndrome coronavirus].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2005;26(1):22-4.
2005: Bo-Jian Zheng; Yi Guan; Ming-Liang Hez; Hongzhe Sun; Lanying Du; Ying Zheng; Kin-Ling Wong; Honglin Chen; Ying Chen; Linyu Lu; Julian Tanner; Rory Munro Watt; Neri Niccolai; Andrea Bernini; ottavia spiga; Patrick C Y Woo; Hsiang-Fu Kung; Kwok-Yung Yuen; Jian-Dong Huang
Synthetic peptides outside the spike protein heptad repeat regions as potent inhibitors of SARS-associated coronavirus.
Antiviral therapy 2005;10(3):393-403.
2005: Biao Di; Wei Hao; Yang Gao; Ming Wang; Ya-di Wang; Li-wen Qiu; Kun Wen; Duan-hua Zhou; Xin-wei Wu; En-jie Lu; Zhi-yong Liao; Ya-bo Mei; Bo-Jian Zheng; Xiao-yan Che
Monoclonal antibody-based antigen capture enzyme-linked immunosorbent assay reveals high sensitivity of the nucleocapsid protein in acute-phase sera of severe acute respiratory syndrome patients.
Clinical and diagnostic laboratory immunology 2005;12(1):135-40.
2004: Ming Wang; Hui-fang Xu; Zi-yao Mo; Bo-Jian Zheng; Jing Gu; Peng-Zhe Qin; Zhou-Bin Zhang; Xiao-Zhong Zou; Cai-Yun Liang; Yu-Teng Zhao; Kai Gao
Anti-SARS virus antibody responses against human SARS-associated coronavirus and animal SARS-associated coronavirus-like virus.
Chinese medical journal 2004;117(11):1723-5.
2004: Xiu-Ying Zhao; Shui-Shan Lee; Ka-Hing Wong; Kenny Chi-Wai Chan; Zhu-Mei He; Selene Ma; Fai Ng; Chris Chung-Sing Chan; Tina Ho; Mun-Hon Ng; Bo-Jian Zheng
A novel CCR5 mutation selectively affects immunoreactivity and fusogenic property of the HIV co-receptor.
AIDS (London, England) 2004;18(12):1729-32.
2004: X-Y Zhao; S S Lee; K H Wong; K C W Chan; S Ma; Wing-Cheong Yam; K Y Yuen; M H Ng; Bo-Jian Zheng
Effects of single nucleotide polymorphisms in the RANTES promoter region in healthy and HIV-infected indigenous Chinese.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2004;31(4):179-83.
2004: Bo-Jian Zheng; Yi Guan; Qingquan Tang; Cheng Du; Frank Y Xie; Ming-Liang He; Kwok Wah Chan; Kin-Ling Wong; Eric Lader; Martin C Woodle; Patrick Y Lu; Baojian Li; Nanshan Zhong
Prophylactic and therapeutic effects of small interfering RNA targeting SARS-coronavirus.
Antiviral therapy 2004;9(3):365-74.
2004: Bo-Jian Zheng; Jie Zhou; Di Qu; Kam-Leung Siu; Ting Wa Lam; Hong Yuen Lo; S S Lee; Yu-Mei Wen
Selective functional deficit in dendritic cell--T cell interaction is a crucial mechanism in chronic hepatitis B virus infection.
Journal of viral hepatitis 2004;11(3):217-24.
2004: Patrick C Y Woo; Susanna K P Lau; Hoi-Wah Tsoi; Kwok-Hung Chan; Beatrice H L Wong; Xiao-yan Che; Victoria K P Tam; Sidney C F Tam; V C C Cheng; I F N Hung; Samson S Y Wong; Bo-Jian Zheng; Yi Guan; Kwok-Yung Yuen
Relative rates of non-pneumonic SARS coronavirus infection and SARS coronavirus pneumonia.
Lancet 2004;363(9412):841-5.
2004: V C C Cheng; I F N Hung; Bone S F Tang; Chung-Ming Chu; M M L Wong; Kwok-Hung Chan; A K L Wu; Doris M W Tse; Kin-Sang Chan; Bo-Jian Zheng; J S M Peiris; J J Y Sung; Kwok-Yung Yuen
Viral replication in the nasopharynx is associated with diarrhea in patients with severe acute respiratory syndrome.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;38(4):467-75.
2004: Bo-Jian Zheng; Ka-Hing Wong; Jie Zhou; Kin-Ling Wong; Betty Wan Y Young; Li Wei Lu; Shui Shan Lee
SARS-related virus predating SARS outbreak, Hong Kong.
Emerging infectious diseases 2004;10(2):176-8.
2003: Nan-shan Zhong; Bo-Jian Zheng; Yi-min Li; Z H Xie; K H Chan; P H Li; S Y Tan; Q Chang; J P Xie; xiaoqing liu; Jun Xu; D X Li; K Y Yuen; Y Guan
Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003.
Lancet 2003;362(9393):1353-8.
2003: Yi Guan; Bo-Jian Zheng; Y Q He; X L Liu; Z X Zhuang; Chung-Lam Cheung; Shi-Wei Luo; P H Li; LJ Zhang; Y J Guan; K M Butt; Kin-Ling Wong; Kwok Wah Chan; Wilina Lim; Kennedy F Shortridge; Kwok-Yung Yuen; J S M Peiris; Leo Poon
Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.
Science (New York, N.Y.) 2003;302(5643):276-8.
2003: J S M Peiris; Chung-Ming Chu; V C C Cheng; Kin-Sang Chan; I F N Hung; Leo Poon; Kin Ip Law; Bone S F Tang; Timothy Yu-Wai Hon; CS Chan; Kwok-Hung Chan; J S C Ng; Bo-Jian Zheng; Woon Leung Ng; Raymond W M Lai; Yi Guan; Kwok-Yung Yuen
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.
Lancet 2003;361(9371):1767-72.
2002: Bo-Jian Zheng; Xiu-Ying Zhao; Nai-shuo Zhu; Cangel Pui-Yee Chan; Ka-Hing Wong; Kenny Chi-Wai Chan; Wing-Cheong Yam; Kwok-Yung Yuen; Shui-Shan Lee
Polymorphisms of CCR5 gene in a southern Chinese population and their effects on disease progression in HIV infections.
AIDS (London, England) 2002;16(18):2480-2.
2002: Bo-Jian Zheng; Mun-Hon Ng; Kwok Wah Chan; Sidney Tam; Patrick C Y Woo; Sze Park Ng; Kwok-Yung Yuen
A single dose of oral DNA immunization delivered by attenuated Salmonella typhimurium down-regulates transgene expression in HBsAg transgenic mice.
European journal of immunology 2002;32(11):3294-304.
2002: Bo-Jian Zheng; Sze Park Ng; Daniel T T Chua; Jonathan S T Sham; Dora L W Kwong; Clarence K Lam; Mun-Hon Ng
Peripheral gamma delta T-cell deficit in nasopharyngeal carcinoma.
International journal of cancer. Journal international du cancer 2002;99(2):213-7.
2002: Wei-min Cheng; Kwok-Hung Chan; Hong-lin Chen; Rui-xian Luo; Sze Park Ng; Winsie Luk; Bo-Jian Zheng; Ming-fang Ji; Jin-sheng Liang; Jonathan S T Sham; De-kun Wang; Yong-Sheng Zong; Mun-Hon Ng
Assessing the risk of nasopharyngeal carcinoma on the basis of EBV antibody spectrum.
International journal of cancer. Journal international du cancer 2002;97(4):489-92.
2001: Bo-Jian Zheng; Mun-Hon Ng; Li-Fang He; Xin Yao; Kwok Wah Chan; Kwok-Yung Yuen; Yu-Mei Wen
Therapeutic efficacy of hepatitis B surface antigen-antibodies-recombinant DNA composite in HBsAg transgenic mice.
Vaccine 2001;19(30):4219-25.
2001: Bo-Jian Zheng; Kwok Wah Chan; S Im; Daniel T T Chua; Jonathan S T Sham; Pui-Chi Tin; Zhu-Mei He; Mun-Hon Ng
Anti-tumor effects of human peripheral gammadelta T cells in a mouse tumor model.
International journal of cancer. Journal international du cancer 2001;92(3):421-5.
2001: Patrick C Y Woo; Lei-Po Wong; Bo-Jian Zheng; Kwok-Yung Yuen
Unique immunogenicity of hepatitis B virus DNA vaccine presented by live-attenuated Salmonella typhimurium.
Vaccine 2001;19(20-22):2945-54.