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Anthony Brown

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Yoshimi Endo Greer; Anthony M C Brown; Alan P Fields; Jeffrey S Rubin
Atypical protein kinase Cι is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2.
José M González-Sancho; Yoshimi Endo Greer; Kyung Ho Lee; Kyung S Lee; Jeffrey S Rubin; Yutaka Takigawa; Cristina L Abrahams; Bolormaa Baljinnyam; Anthony M C Brown
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
Francisco Santiago; Junya Oguma; Anthony M C Brown; Jeffrey Laurence
Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir.

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All Publications

2013: Yoshimi Endo Greer; Anthony M C Brown; Alan P Fields; Jeffrey S Rubin
Atypical protein kinase Cι is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2.
The Journal of biological chemistry 2013;288(13):9438-46.
2013: José M González-Sancho; Yoshimi Endo Greer; Kyung Ho Lee; Kyung S Lee; Jeffrey S Rubin; Yutaka Takigawa; Cristina L Abrahams; Bolormaa Baljinnyam; Anthony M C Brown
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
The Journal of biological chemistry 2013;288(13):9428-37.
2012: Francisco Santiago; Junya Oguma; Anthony M C Brown; Jeffrey Laurence
Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir.
Biochemical and biophysical research communications 2012;417(1):223-30.
2011: Foster Gonsalves; Keren Klein; Brittany B Carson; Shauna Katz; Laura A Ekas; Steve Evans; Robert Nagourney; Timothy Cardozo; Anthony M C Brown; Ramanuj DasGupta
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(15):5954-63.
2008: Yutaka Takigawa; Anthony M C Brown
Wnt signaling in liver cancer.
Current drug targets 2008;9(11):1013-24.
2007: Norio Tezuka; Anthony M C Brown; Shin-ichi Yanagawa
GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway.
Biochemical and biophysical research communications 2007;356(3):648-54.
2006: T Néstor H Masckauchán; Dritan Agalliu; Marina Vorontchikhina; Audrey Ahn; Nancy L Parmalee; Chi-Ming Li; Alan Khoo; Benjamin Tycko; Anthony M C Brown; Jan Kitajewski
Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2.
Molecular biology of the cell 2006;17(12):5163-72.
2005: Louise R Howe; Sung-Hee Chang; Kelly C Tolle; Rachelle Dillon; Lawrence J T Young; Robert Cardiff; Robert A Newman; Peiying Yang; Howard T Thaler; William J Muller; Clifford Hudis; Anthony M C Brown; Timothy Hla; Kotha Subbaramaiah; Andrew J Dannenberg
HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.
Cancer research 2005;65(21):10113-9.
2005: Anthony M C Brown
Canonical Wnt signaling: high-throughput RNAi widens the path.
Genome biology 2005;6(9):231.
2004: Catherine Chesnutt; Laura W Burrus; Anthony M C Brown; Lee Niswander
Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity.
Developmental biology 2004;274(2):334-47.
2004: Keith Brennan; José M Gonzalez-Sancho; Leslie A Castelo-Soccio; Louise R Howe; Anthony M C Brown
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.
Oncogene 2004;23(28):4873-84.
2004: Peter J Morin; Miguel Medina; Mikhail Semenov; Anthony M C Brown; Kenneth S Kosik
Wnt-1 expression in PC12 cells induces exon 15 deletion and expression of L-APP.
Neurobiology of disease 2004;16(1):59-67.
2004: José Manuel González-Sancho; Keith R Brennan; Leslie A Castelo-Soccio; Anthony M C Brown
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin.
Molecular and cellular biology 2004;24(11):4757-68.
2004: Keith R Brennan; Anthony M C Brown
Wnt proteins in mammary development and cancer.
Journal of mammary gland biology and neoplasia 2004;9(2):119-31.
2004: Louise R Howe; Anthony M C Brown
Wnt signaling and breast cancer.
Cancer biology & therapy 2004;3(1):36-41.
2003: Kelly Anakwe; Lesley Robson; Julia Hadley; Paul Buxton; Vicki Church; Steve Allen; Christine Hartmann; Brian D Harfe; Tsutomu Nohno; Anthony M C Brown; Darrell J R Evans; Philippa Francis-West
Wnt signalling regulates myogenic differentiation in the developing avian wing.
Development (Cambridge, England) 2003;130(15):3503-14.
2003: Louise R Howe; Osamu Watanabe; James Leonard; Anthony M C Brown
Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation.
Cancer research 2003;63(8):1906-13.
2003: Keith Brennan; Anthony M C Brown
Is there a role for Notch signalling in human breast cancer?
Breast cancer research : BCR 2003;5(2):69-75.
2002: Edmund Wong; Kan Yang; Mari Kuraguchi; Uwe Werling; Elena Avdievich; Kunhua Fan; Melissa Fazzari; Bo Jin; Anthony M C Brown; Martin Lipkin; Winfried Edelmann
Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):14937-42.
2002: Louise R Howe; Kotha Subbaramaiah; Jay Patel; Jaime L Masferrer; Aparna Deora; Clifford Hudis; Howard T Thaler; William J Muller; Baoheng Du; Anthony M C Brown; Andrew J Dannenberg
Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer.
Cancer research 2002;62(19):5405-7.
2002: Melanie Haas Kucherlapati; Kan Yang; Mari Kuraguchi; Jie Zhao; Mariel Lia; Joerg Heyer; Michael F Kane; Kunhua Fan; Robert Russell; Anthony M C Brown; Burkhard Kneitz; Winfried Edelmann; Richard D Kolodner; Martin Lipkin; Raju Kucherlapati
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9924-9.
2002: Zongbing You; Daniel Saims; Shaoqiong Chen; Zhaocheng Zhang; Denis C Guttridge; Kun-Liang Guan; Ormond A MacDougald; Anthony M C Brown; Gerard Evan; Jan Kitajewski; Cun-Yu Wang
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.
The Journal of cell biology 2002;157(3):429-40.
2001: Mari Kuraguchi; Kan Yang; Edmund Wong; Elena Avdievich; Kunhua Fan; Richard D Kolodner; Martin Lipkin; Anthony M C Brown; Raju Kucherlapati; Winfried Edelmann
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.
Cancer research 2001;61(21):7934-42.
2001: Louise R Howe; Howard C Crawford; Kotha Subbaramaiah; J A Hassell; Andrew J Dannenberg; Anthony M C Brown
PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2.
The Journal of biological chemistry 2001;276(23):20108-15.
2001: Louise R Howe; Kotha Subbaramaiah; Anthony M C Brown; Andrew J Dannenberg
Cyclooxygenase-2: a target for the prevention and treatment of breast cancer.
Endocrine-related cancer 2001;8(2):97-114.
2001: Anthony M C Brown
Wnt signaling in breast cancer: have we come full circle?
Breast cancer research : BCR 2001;3(6):351-5.
2000: Mari Kuraguchi; Winfried Edelmann; Kan Yang; Martin Lipkin; Raju Kucherlapati; Anthony M C Brown
Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency.
Oncogene 2000;19(50):5755-63.
2000: Anne-Gaëlle Borycki; Anthony M C Brown; Charles P Emerson
Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites.
Development (Cambridge, England) 2000;127(10):2075-87.
1999: Louise R Howe; Kotha Subbaramaiah; W J Chung; Andrew J Dannenberg; Anthony M C Brown
Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells.
Cancer research 1999;59(7):1572-7.
1999: Winfried Edelmann; Kan Yang; Mari Kuraguchi; Joerg Heyer; Mariel Lia; Burkhard Kneitz; Kunhua Fan; Anthony M C Brown; Martin Lipkin; Raju Kucherlapati
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.
Cancer research 1999;59(6):1301-7.