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Dujin Zhou

Research Profile

Chemicals & Drugs

Disorders

Breast Neoplasms

Concepts & Ideas

Anatomy

Tumor Cells, Cultured

Physiology

Genes & Molecular Sequences

Amino Acid Sequences

Phenomena

Protein Binding

Co-author Network

Publications

TOP 3
Yuanzhong Wang; Dujin Zhou; Sheryl Phung; Selma Masri; David Smith; Shiuan Chen
SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells.
Selma Masri; Ki Lui; Sheryl Phung; Jingjing Ye; Dujin Zhou; Xin Wang; Shiuan Chen
Characterization of the weak estrogen receptor alpha agonistic activity of exemestane.
Ki Lui; Takaya Tamura; Taisuke Mori; Dujin Zhou; Shiuan Chen
MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands.

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All Publications

2011: Yuanzhong Wang; Dujin Zhou; Sheryl Phung; Selma Masri; David Smith; Shiuan Chen
SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 2011;25(1):72-82.
2009: Selma Masri; Ki Lui; Sheryl Phung; Jingjing Ye; Dujin Zhou; Xin Wang; Shiuan Chen
Characterization of the weak estrogen receptor alpha agonistic activity of exemestane.
Breast cancer research and treatment 2009;116(3):461-70.
2008: Ki Lui; Takaya Tamura; Taisuke Mori; Dujin Zhou; Shiuan Chen
MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands.
Biochemical pharmacology 2008;76(2):208-15.
2008: Dujin Zhou; Ruoqing Shen; Jing Jing Ye; Yuping Li; Walter Tsark; Donna Isbell; Patrick Tso; Shiuan Chen
Nuclear receptor coactivator PNRC2 regulates energy expenditure and adiposity.
The Journal of biological chemistry 2008;283(1):541-53.
2007: Yanyan Hong; Bin Yu; Mark Sherman; Yate-Ching Yuan; Dujin Zhou; Shiuan Chen
Molecular basis for the aromatization reaction and exemestane-mediated irreversible inhibition of human aromatase.
Molecular endocrinology (Baltimore, Md.) 2007;21(2):401-14.
2007: Dujin Zhou; Shuping Zhong; Jing-Jing Ye; Keith M Quach; Deborah L Johnson; Shiuan Chen
PNRC is a unique nuclear receptor coactivator that stimulates RNA polymerase III-dependent transcription.
Journal of molecular signaling 2007;2():5.
2006: Dujin Zhou; Jing Jing Ye; Yuping Li; Ki Lui; Shiuan Chen
The molecular basis of the interaction between the proline-rich SH3-binding motif of PNRC and estrogen receptor alpha.
Nucleic acids research 2006;34(20):5974-86.
2005: Dujin Zhou; Selma Masri; Jing Jing Ye; Shiuan Chen
Transcriptional regulation of the mouse PNRC2 promoter by the nuclear factor Y (NFY) and E2F1.
Gene 2005;361():89-100.
2005: Shiuan Chen; Jingjing Ye; Ikuko Kijima; Yoshiyuki Kinoshita; Dujin Zhou
Positive and negative transcriptional regulation of aromatase expression in human breast cancer tissue.
The Journal of steroid biochemistry and molecular biology 2005;95(1-5):17-23.
2004: Shiuan Chen; Michael Cho; Kimberly Karlsberg; Dujin Zhou; Yate-Ching Yuan
Biochemical and biological characterization of a novel anti-aromatase coumarin derivative.
The Journal of biological chemistry 2004;279(46):48071-8.
2004: Dujin Zhou; Bin Chen; Jing-Jing Ye; Shiuan Chen
A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interaction.
Oncogene 2004;23(31):5394-404.
2003: Shiuan Chen; Fangming Zhang; Mark A Sherman; Ikuko Kijima; Michael Cho; Yate-Ching Yuan; Yoshiro Toma; Yoshio Osawa; Dujin Zhou; Elizabeth T Eng
Structure-function studies of aromatase and its inhibitors: a progress report.
The Journal of steroid biochemistry and molecular biology 2003;86(3-5):231-7.
2002: Shiuan Chen; Toru Itoh; Kebin Wu; Dujin Zhou; Chun Yang
Transcriptional regulation of aromatase expression in human breast tissue.
The Journal of steroid biochemistry and molecular biology 2002;83(1-5):93-9.
2002: Fangming Zhang; Dujin Zhou; Yeh-Chih Kao; Jingjing Ye; Shiuan Chen
Expression and purification of a recombinant form of human aromatase from Escherichia coli.
Biochemical pharmacology 2002;64(9):1317-24.
2002: Shiuan Chen; Dujin Zhou; Tomoharu Okubo; Yeh-Chih Kao; Elizabeth T Eng; Baiba Grube; Annette Kwon; Chun Yang; Bin Yu
Prevention and treatment of breast cancer by suppressing aromatase activity and expression.
Annals of the New York Academy of Sciences 2002;963():229-38.
2002: Chun Yang; Bin Yu; Dujin Zhou; Shiuan Chen
Regulation of aromatase promoter activity in human breast tissue by nuclear receptors.
Oncogene 2002;21(18):2854-63.
2001: Shiuan Chen; Dujin Zhou; Chun Yang; Tomoharu Okubo; Yoshiyuki Kinoshita; Bin Yu; Yeh-Chih Kao; Toru Itoh
Modulation of aromatase expression in human breast tissue.
The Journal of steroid biochemistry and molecular biology 2001;79(1-5):35-40.
2001: Dujin Zhou; Shiuan Chen
PNRC2 is a 16 kDa coactivator that interacts with nuclear receptors through an SH3-binding motif.
Nucleic acids research 2001;29(19):3939-48.
2001: Shiuan Chen; Dujin Zhou; Chun Yang; Mark Sherman
Molecular basis for the constitutive activity of estrogen-related receptor alpha-1.
The Journal of biological chemistry 2001;276(30):28465-70.
2001: Tomoharu Okubo; T K Truong; Bin Yu; Toru Itoh; J Zhao; Baiba Grube; Dujin Zhou; Shiuan Chen
Down-regulation of promoter 1.3 activity of the human aromatase gene in breast tissue by zinc-finger protein, snail (SnaH).
Cancer research 2001;61(4):1338-46.
2000: Dujin Zhou; K M Quach; Chun Yang; S Y Lee; B Pohajdak; Shiuan Chen
PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1).
Molecular endocrinology (Baltimore, Md.) 2000;14(7):986-98.
1999: Dujin Zhou; Shiuan Chen
Identification and characterization of a cAMP-responsive element in the region upstream from promoter 1.3 of the human aromatase gene.
Archives of biochemistry and biophysics 1999;371(2):179-90.
1999: Shiuan Chen; Dujin Zhou; Tomoharu Okubo; Yeh-Chih Kao; Chun Yang
Breast tumor aromatase: functional role and transcriptional regulation.
Endocrine-related cancer 1999;6(2):149-56.
1998: Chun Yang; Dujin Zhou; Shiuan Chen
Modulation of aromatase expression in the breast tissue by ERR alpha-1 orphan receptor.
Cancer research 1998;58(24):5695-700.
1998: Dujin Zhou; Shiuan Chen
Characterization of a silencer element in the human aromatase gene.
Archives of biochemistry and biophysics 1998;353(2):213-20.
1997: X Z Sun; Dujin Zhou; Shiuan Chen
Autocrine and paracrine actions of breast tumor aromatase. A three-dimensional cell culture study involving aromatase transfected MCF-7 and T-47D cells.
The Journal of steroid biochemistry and molecular biology 1997;63(1-3):29-36.
1997: Dujin Zhou; C Zhou; Shiuan Chen
Gene regulation studies of aromatase expression in breast cancer and adipose stromal cells.
The Journal of steroid biochemistry and molecular biology 1997;61(3-6):273-80.
1997: Shiuan Chen; R Knox; K Wu; P S Deng; Dujin Zhou; Mario Antonio Bianchet; Mario Amzel
Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse.
The Journal of biological chemistry 1997;272(3):1437-9.
1996: C Zhou; Dujin Zhou; J Esteban; JT Murai; Pentti Siiteri; S Wilczynski; Shiuan Chen
Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction.
The Journal of steroid biochemistry and molecular biology 1996;59(2):163-71.
1996: Yeh-Chih Kao; L L Cam; C A Laughton; Dujin Zhou; Shiuan Chen
Binding characteristics of seven inhibitors of human aromatase: a site-directed mutagenesis study.
Cancer research 1996;56(15):3451-60.
1996: Dujin Zhou; P Clarke; J Wang; Shiuan Chen
Identification of a promoter that controls aromatase expression in human breast cancer and adipose stromal cells.
The Journal of biological chemistry 1996;271(25):15194-202.
1994: Dujin Zhou; L L Cam; C A Laughton; K R Korzekwa; Shiuan Chen
Mutagenesis study at a postulated hydrophobic region near the active site of aromatase cytochrome P450.
The Journal of biological chemistry 1994;269(30):19501-8.
1993: Dujin Zhou; J Wang; E Chen; JT Murai; Pentti Siiteri; Shiuan Chen
Aromatase gene is amplified in MCF-7 human breast cancer cells.
The Journal of steroid biochemistry and molecular biology 1993;46(2):147-53.
1993: Shiuan Chen; Dujin Zhou; KM Swiderek; N Kadohama; Yoshio Osawa; P F Hall
Structure-function studies of human aromatase.
The Journal of steroid biochemistry and molecular biology 1993;44(4-6):347-56.
1992: Shiuan Chen; Dujin Zhou
Functional domains of aromatase cytochrome P450 inferred from comparative analyses of amino acid sequences and substantiated by site-directed mutagenesis experiments.
The Journal of biological chemistry 1992;267(31):22587-94.