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Tong Zhou

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TOP 3
Zilu Zhu; Hao Li; Ran Li; Tong Zhou; Randall S Davis
FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling.
Qi Yan; Tong Zhou; Jay M McDonald; Yuhua Song
Structural insight for the roles of fas death domain binding to FADD and oligomerization degree of the Fas-FADD complex in the death-inducing signaling complex formation: a computational study.
Larissa Sweeny; Tong Zhou; Benjamin D Bush; Yolanda Hartman; Zhiyong Liu; Eben L Rosenthal
CD147 and AGR2 expression promote cellular proliferation and metastasis of head and neck squamous cell carcinoma.

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All Publications

2013: Zilu Zhu; Hao Li; Ran Li; Tong Zhou; Randall S Davis
FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(14):E1282-90.
2013: Qi Yan; Tong Zhou; Jay M McDonald; Yuhua Song
Structural insight for the roles of fas death domain binding to FADD and oligomerization degree of the Fas-FADD complex in the death-inducing signaling complex formation: a computational study.
Proteins 2013;81(3):377-85.
2012: Larissa Sweeny; Tong Zhou; Benjamin D Bush; Yolanda Hartman; Zhiyong Liu; Eben L Rosenthal
CD147 and AGR2 expression promote cellular proliferation and metastasis of head and neck squamous cell carcinoma.
Experimental cell research 2012;318(14):1788-98.
2012: Patsy G Oliver; Guihua Zhai; Tong Zhou; Kurt R Zinn; Andres Forero; Hyunki Kim; Choo H Lee; Yufeng Li; Albert F LoBuglio; Donald J Buchsbaum
Effect of anti-DR5 and chemotherapy on basal-like breast cancer.
Breast cancer research and treatment 2012;133(2):417-26.
2012: Nemil Shah; Cecil R Stockard; Guihua Zhai; Tong Zhou; Kurt R Zinn; Naomi S Fineberg; William E Grizzle; Joseph A Knowles; Eben Rosenthal; Hyunki Kim
(18)F-FDG PET/CT imaging detects therapy efficacy of anti-EMMPRIN antibody and gemcitabine in orthotopic pancreatic tumor xenografts.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2012;14(2):237-44.
2011: Hyunki Kim; Joseph A Knowles; Zhiyong Liu; Sharon Samuel; Nemil Shah; Cecil R Stockard; Guihua Zhai; Tong Zhou; Kurt R Zinn; Naomi S Fineberg; William E Grizzle; Emily E Helman; Eben Rosenthal
Extracelluar matrix metalloproteinase as a novel target for pancreatic cancer therapy.
Anti-cancer drugs 2011;22(9):864-74.
2011: Zhiyong Liu; Yolanda E Hartman; Joseph A Knowles; Larissa Sweeny; Jason M Warram; Tong Zhou; Eben Rosenthal
Fibroblast growth factor receptor mediates fibroblast-dependent growth in EMMPRIN-depleted head and neck cancer tumor cells.
Molecular cancer research : MCR 2011;9(8):1008-17.
2011: Hope M Amm; Tong Zhou; Adam D Steg; Huichien Kuo; Yufeng Li; Donald J Buchsbaum
Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells.
Molecular cancer research : MCR 2011;9(4):403-17.
2011: Mianen Sun; Ling Song; Tong Zhou; G Yancey Gillespie; Richard Scott Jope
The role of DDX3 in regulating Snail.
Biochimica et biophysica acta 2011;1813(3):438-47.
2010: Fumiaki Yokoi; Guang Yang; Jindong Li; Mark P DeAndrade; Tong Zhou; Y Li
Earlier onset of motor deficits in mice with double mutations in Dyt1 and Sgce.
Journal of biochemistry 2010;148(4):459-66.
2009: Peter J Frederick; James E Kendrick; J Michael Straughn; Debbie L Della Manna; Patsy G Oliver; Hui-Yi Lin; William E Grizzle; Cecil R Stockard; Ronald D Alvarez; Tong Zhou; Albert F LoBuglio; Donald J Buchsbaum
Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2009;19(5):814-9.
2008: M Sun; Ling Song; Y Li; Tong Zhou; Richard Scott Jope
Identification of an antiapoptotic protein complex at death receptors.
Cell death and differentiation 2008;15(12):1887-900.
2008: Xinrui Li; Kaihong Su; Chuanyi Ji; Alexander Szalai; Jianming Wu; Yan Zhang; Tong Zhou; Robert P Kimberly; Jeffrey C Edberg
Immune opsonins modulate BLyS/BAFF release in a receptor-specific fashion.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1012-8.
2008: John B Fiveash; G Yancey Gillespie; Patsy G Oliver; Tong Zhou; Michael L Belenky; Donald J Buchsbaum
Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5.
International journal of radiation oncology, biology, physics 2008;71(2):507-16.
2008: Patsy G Oliver; Albert F LoBuglio; Kurt R Zinn; Hyunki Kim; Li Nan; Tong Zhou; Wenquan Wang; Donald J Buchsbaum
Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(7):2180-9.
2007: Leo Christopher DeRosier; Selwyn M Vickers; Kurt R Zinn; Zhi Huang; Wenquan Wang; William E Grizzle; Jeffrey Sellers; Cecil R Stockard; Tong Zhou; Patsy G Oliver; Pablo Arnoletti; Albert F LoBuglio; Donald J Buchsbaum
TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth.
Molecular cancer therapeutics 2007;6(12 Pt 1):3198-207.
2007: Leo Christopher DeRosier; Donald J Buchsbaum; Patsy G Oliver; Zhi-Qiang Huang; Jeffrey C Sellers; William E Grizzle; Wenquan Wang; Tong Zhou; Kurt R Zinn; Joshua W Long; Selwyn M Vickers
Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(18 Pt 2):5535s-5543s.
2007: Jacob M Estes; Patsy G Oliver; J Michael Straughn; Tong Zhou; Wenquan Wang; William E Grizzle; Ronald D Alvarez; Cecil R Stockard; Albert F LoBuglio; Donald J Buchsbaum
Efficacy of anti-death receptor 5 (DR5) antibody (TRA-8) against primary human ovarian carcinoma using a novel ex vivo tissue slice model.
Gynecologic oncology 2007;105(2):291-8.
2007: Kaihong Su; Hengxuan Yang; Xiaoli Li; Xiaoli Li; Andrew W Gibson; John M Cafardi; Tong Zhou; Jeffrey C Edberg; Robert P Kimberly
Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):3272-80.
2006: Yang Li; Hong Wang; Zheng Wang; Sharmila K Makhija; Donald J Buchsbaum; Albert F LoBuglio; Robert P Kimberly; Tong Zhou
Inducible resistance of tumor cells to tumor necrosis factor-related apoptosis-inducing ligand receptor 2-mediated apoptosis by generation of a blockade at the death domain function.
Cancer research 2006;66(17):8520-8.
2006: Donald J Buchsbaum; Tong Zhou; Albert F LoBuglio
TRAIL receptor-targeted therapy.
Future oncology (London, England) 2006;2(4):493-508.
2006: J Michael Straughn; Patsy G Oliver; Tong Zhou; Wenquan Wang; Ronald D Alvarez; William E Grizzle; Donald J Buchsbaum
Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model.
Gynecologic oncology 2006;101(1):46-54.
2006: Sergey A Kaliberov; S Chiz; Lyudmila N Kaliberova; Valentina Krendelchtchikova; Debbie Della Manna; Tong Zhou; Donald J Buchsbaum
Combination of cytosine deaminase suicide gene expression with DR5 antibody treatment increases cancer cell cytotoxicity.
Cancer gene therapy 2006;13(2):203-14.
2006: Hui-Chen Hsu; Tong Zhou; Helen Kim; Stephen Barnes; Pingar Yang; Qi Wu; Juling Zhou; Bruce Freeman; Ming Luo; John D Mountz
Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis.
Arthritis and rheumatism 2006;54(1):343-55.
2005: Robert H Carter; Hong Zhao; Ximeng Liu; Marc Pelletier; Winn Chatham; Robert P Kimberly; Tong Zhou
Expression and occupancy of BAFF-R on B cells in systemic lupus erythematosus.
Arthritis and rheumatism 2005;52(12):3943-54.
2004: Hui-Chen Hsu; Tong Zhou; John D Mountz
Nur77 family of nuclear hormone receptors.
Current drug targets. Inflammation and allergy 2004;3(4):413-23.
2004: Tong Zhou; Hong Wang; Danlin Luo; Thomas Rowe; Zheng Wang; Robert Jeffrey Hogan; Shihong Qiu; Robert J Bunzel; Guoqiang Huang; Vinod Mishra; Thomas G Voss; Robert P Kimberly; Ming Luo
An exposed domain in the severe acute respiratory syndrome coronavirus spike protein induces neutralizing antibodies.
Journal of virology 2004;78(13):7217-26.
2004: Weimin Liu; Alexander Szalai; Limin Zhao; Di Liu; Flavius Martin; Robert P Kimberly; Tong Zhou; Robert H Carter
Control of spontaneous B lymphocyte autoimmunity with adenovirus-encoded soluble TACI.
Arthritis and rheumatism 2004;50(6):1884-96.
2004: Ling Song; Tong Zhou; Richard Scott Jope
Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor.
BMC neuroscience 2004;5():20.
2004: Sergey A Kaliberov; Murray A Stackhouse; Lyudmila N Kaliberova; Tong Zhou; Donald J Buchsbaum
Enhanced apoptosis following treatment with TRA-8 anti-human DR5 monoclonal antibody and overexpression of exogenous Bax in human glioma cells.
Gene therapy 2004;11(8):658-67.
2003: Donald J Buchsbaum; Tong Zhou; William E Grizzle; Patsy G Oliver; Charlotte J Hammond; Sijian Zhang; Mark Carpenter; Albert F LoBuglio
Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3731-41.
2003: Yuanyuan Xu; Alexander Szalai; Tong Zhou; Kurt R Zinn; Tandra R Chaudhuri; Xiaoli Li; William J Koopman; Robert P Kimberly
Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: implications for agonistic antibody-based therapeutics.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):562-8.
2003: Tong Zhou; Jun Zhang; Robert Carter; Robert P Kimberly
BLyS and B cell autoimmunity.
Current directions in autoimmunity 2003;6():21-37.
2002: Y Matsuki; Huang-Ge Zhang; Hui-Chen Hsu; Ping-Ar Yang; Tong Zhou; Christopher H Dodd; Francesco Cecconi; P Gruss; T Tadakuma; John D Mountz
Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture.
Scandinavian journal of immunology 2002;56(2):174-84.
2002: Chulhee Choi; Olaf Kutsch; Jinseu Park; Tong Zhou; Dai-Wu Seol; Etty N Benveniste
Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells.
Molecular and cellular biology 2002;22(3):724-36.
2002: Tong Zhou; John D Mountz; Robert P Kimberly
Immunobiology of tumor necrosis factor receptor superfamily.
Immunologic research 2002;26(1-3):323-36.
2002: Huang-Ge Zhan; John D Mountz; Martin Fleck; Tong Zhou; Hui-Chen Hsu
Specific deletion of autoreactive T cells by adenovirus-transfected, Fas ligand-producing antigen-presenting cells.
Immunologic research 2002;26(1-3):235-46.
2001: Hui-Chen Hsu; Huang-Ge Zhang; G G Song; J Xie; Di Liu; Ping-Ar Yang; Martin Fleck; W Wintersberger; Tong Zhou; Carl K Edwards; John D Mountz
Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection.
Arthritis and rheumatism 2001;44(9):2146-59.
2001: Hui-Chen Hsu; Tong Zhou; J Shi; Ping-Ar Yang; Di Liu; Huang-Ge Zhang; H Bluethmann; John D Mountz
Aged mice exhibit in vivo defective peripheral clonal deletion of D(b)/H-Y reactive CD8(+) T cells.
Mechanisms of ageing and development 2001;122(3):305-26.
2001: Hui-Chen Hsu; Y Matsuki; Huang-Ge Zhang; Tong Zhou; John D Mountz
The Fas signaling connection between autoimmunity and embryonic lethality.
Journal of clinical immunology 2001;21(1):1-14.
2000: Huang-Ge Zhang; Jinfu Xie; Pingar Yang; Yongming Wang; Liang Xu; D Liu; Hui-Chen Hsu; Tong Zhou; Carl K Edwards; John D Mountz
Adeno-associated virus production of soluble tumor necrosis factor receptor neutralizes tumor necrosis factor alpha and reduces arthritis.
Human gene therapy 2000;11(17):2431-42.
2000: Huang-Ge Zhang; N Huang; Di Liu; L Bilbao; X Zhang; Pingar Yang; Tong Zhou; D T Curiel; John D Mountz
Gene therapy that inhibits nuclear translocation of nuclear factor kappaB results in tumor necrosis factor alpha-induced apoptosis of human synovial fibroblasts.
Arthritis and rheumatism 2000;43(5):1094-105.
2000: Sun Jung Lee; Tong Zhou; Chulhee Choi; Z Wang; Etty N Benveniste
Differential regulation and function of Fas expression on glial cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1277-85.
1999: Guadalupe Bilbao; H Zhang; Juan L Contreras; Tong Zhou; M Feng; I Saito; John D Mountz; David T Curiel
Construction of a recombinant adenovirus vector encoding Fas ligand with a CRE/Loxp inducible system.
Transplantation proceedings 1999;31(1-2):792-3.
1999: Huang-Ge Zhang; X Su; Di Liu; W Liu; Pingar Yang; Z Wang; Carl K Edwards; H Bluethmann; John D Mountz; Tong Zhou
Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1423-30.
1999: Hui-Chen Hsu; John D Mountz; Tong Zhou
Regulation of Fas-mediated apoptosis in CD2-fas transgenic mice.
International reviews of immunology 1999;18(4):309-27.
1999: Tong Zhou; Ling Song; Pingar Yang; Z Wang; D Lui; Richard Scott Jope
Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases.
Nature medicine 1999;5(1):42-8.
1998: Huang-Ge Zhang; Di Liu; Y Heike; Pingar Yang; Z Wang; X Wang; David T Curiel; Tong Zhou; John D Mountz
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells.
Nature biotechnology 1998;16(11):1045-9.
1998: Huang-Ge Zhang; Tong Zhou; Pingar Yang; Carl K Edwards; David T Curiel; John D Mountz
Inhibition of tumor necrosis factor alpha decreases inflammation and prolongs adenovirus gene expression in lung and liver.
Human gene therapy 1998;9(13):1875-84.
1998: X Su; J Cheng; W Liu; Cunren Liu; Z Wang; Pingar Yang; Tong Zhou; John D Mountz
Autocrine and paracrine apoptosis are mediated by differential regulation of Fas ligand activity in two distinct Jurkat T cell populations.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5288-93.
1998: Huang-Ge Zhang; Guadalupe Bilbao; Tong Zhou; Juan L Contreras; Jesús Gómez-Navarro; M Feng; I Saito; John D Mountz; David T Curiel
Application of a Fas ligand encoding a recombinant adenovirus vector for prolongation of transgene expression.
Journal of virology 1998;72(3):2483-90.
1998: X Su; Tong Zhou; Pingar Yang; Carl K Edwards; John D Mountz
Reduction of arthritis and pneumonitis in motheaten mice by soluble tumor necrosis factor receptor.
Arthritis and rheumatism 1998;41(1):139-49.
1997: John D Mountz; J Wu; Tong Zhou; Hui-Chen Hsu
Cell death and longevity: implications of Fas-mediated apoptosis in T-cell senescence.
Immunological reviews 1997;160():19-30.
1997: J Cheng; Cunren Liu; Pingar Yang; Tong Zhou; John D Mountz
Increased lymphocyte apoptosis in Fas ligand transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(2):674-84.
1997: Hui-Chen Hsu; Tong Zhou; Ping-Ar Yang; G A Herrera; John D Mountz
Increased acute-phase response and renal amyloidosis in aged CD2-fas-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5988-96.
1997: Tong Zhou; Martin Fleck; U Müeller-Ladner; Pingar Yang; Z Wang; Steffen Gay; S Matsumoto; John D Mountz
Kinetics of Fas-induced apoptosis in thymic organ culture.
Journal of clinical immunology 1997;17(1):74-84.
1996: John D Mountz; Tong Zhou; X Su; J Cheng; M Pierson; H Bluethmann; C K Edwards
Autoimmune disease results from multiple interactive defects in apoptosis induction molecules and signaling pathways.
Behring Institute Mitteilungen 1996;(97):200-19.
1996: Carl K Edwards; Tong Zhou; J Zhang; T J Baker; M De; R E Long; D R Borcherding; T L Bowlin; H Bluethmann; John D Mountz
Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1758-72.
1996: X Su; Tong Zhou; P A Yang; Z Wang; John D Mountz
Hematopoietic cell protein-tyrosine phosphatase-deficient motheaten mice exhibit T cell apoptosis defect.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(11):4198-208.
1996: Tong Zhou; Carl K Edwards; Pingar Yang; Z Wang; H Bluethmann; John D Mountz
Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor I.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2661-5.
1996: Tong Zhou; J Cheng; Pingar Yang; Z Wang; C Liu; X Su; H Bluethmann; John D Mountz
Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells.
The Journal of experimental medicine 1996;183(4):1879-92.
1996: John D Mountz; Carl K Edwards; J Cheng; Pingar Yang; Z Wang; C Liu; X Su; H Bluethmann; Tong Zhou
Autoimmunity due to defective Nur77, Fas, and TNF-RI apoptosis.
Advances in experimental medicine and biology 1996;406():241-62.
1995: John D Mountz; T J Baker; D R Borcherding; H Bluethmann; Tong Zhou; Carl K Edwards
Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4829-37.
1995: John D Mountz; J Cheng; X Su; J Wu; Tong Zhou
Autoimmunity, apoptosis defects and retroviruses.
Advances in experimental medicine and biology 1995;374():183-201.
1995: John D Mountz; Tong Zhou; J Wu; W Wang; X Su; J Cheng
Regulation of apoptosis in immune cells.
Journal of clinical immunology 1995;15(1):1-16.
1994: John D Mountz; J Wu; J Cheng; Tong Zhou
Autoimmune disease. A problem of defective apoptosis.
Arthritis and rheumatism 1994;37(10):1415-20.
1994: Jianming Wu; Tong Zhou; J Zhang; J He; W C Gause; John D Mountz
Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2344-8.
1994: John D Mountz; H Bluethmann; Tong Zhou; Jianming Wu
Defective clonal deletion and anergy induction in TCR transgenic lpr/lpr mice.
Seminars in immunology 1994;6(1):27-37.
1994: John D Mountz; Tong Zhou; R E Long; H Bluethmann; William J Koopman; Carl K Edwards
T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice.
Arthritis and rheumatism 1994;37(1):113-24.
1994: John D Mountz; Tong Zhou; H Bluethmann; Jianming Wu; C K Edwards
Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice.
International reviews of immunology 1994;11(4):321-42.
1993: Tong Zhou; H Bluethmann; J Eldridge; K Berry; John D Mountz
Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3651-67.
1992: Tong Zhou; H Bluethmann; J Zhang; C K Edwards; John D Mountz
Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice.
The Journal of experimental medicine 1992;176(4):1063-72.
1991: Tong Zhou; H Bluethmann; J Eldridge; M Brockhaus; K Berry; John D Mountz
Abnormal thymocyte development and production of autoreactive T cells in T cell receptor transgenic autoimmune mice.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(2):466-74.
1990: John D Mountz; Tong Zhou; J Eldridge; K Berry; H Blüthmann
Transgenic rearranged T cell receptor gene inhibits lymphadenopathy and accumulation of CD4-CD8-B220+ T cells in lpr/lpr mice.
The Journal of experimental medicine 1990;172(6):1805-17.