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Yinghui Zhou

Research Profile

Concepts & Ideas

Activities & Behaviors

Clinical Trials, Phase I as Topic

Chemicals & Drugs

Procedures

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Publications

TOP 3
Gareth James; Yinghui Zhou; Sam Miller
Modeling data with structural and temporal correlation using lower level and higher level multilevel models.
Yinghui Zhou
Adaptive designs for Phase I dose-finding studies.
Roshini Sooriyarachchi; Patrick Kelly; Yinghui Zhou; Nigel Stallard; Helene Thygesen; Clive Bowman
Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme.

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All Publications

2011: Gareth James; Yinghui Zhou; Sam Miller
Modeling data with structural and temporal correlation using lower level and higher level multilevel models.
Pharmaceutical statistics 2011;10(5):395-406.
2010: Yinghui Zhou
Adaptive designs for Phase I dose-finding studies.
Fundamental & clinical pharmacology 2010;24(2):129-38.
2009: Roshini Sooriyarachchi; Patrick Kelly; Yinghui Zhou; Nigel Stallard; Helene Thygesen; Clive Bowman
Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme.
Pharmaceutical statistics 2009;8(4):287-300.
2008: Anne Whitehead; Roshini Sooriyarachchi; Susan Todd; Yinghui Zhou; Michael K Smith
Fitting models for the joint action of two drugs using SAS.
Pharmaceutical statistics 2008;7(4):272-84.
2008: Yinghui Zhou; Roshini Sooriyarachchi; Pasi Korhonen; Mika Mustonen
Implementation of a Bayesian design in a dose-escalation study of an experimental agent in healthy volunteers.
Biometrics 2008;64(1):299-308.
2007: Roshini Sooriyarachchi; Yinghui Zhou; Lisa Hampson; Edouard Ledent; Alvaro Pereira
A Bayesian approach for dose-escalation in a Phase I clinical trial incorporating pharmacodynamic endpoints.
Journal of biopharmaceutical statistics 2007;17(6):1117-29.
2006: Patrick Kelly; Nigel Stallard; Yinghui Zhou; Roshini Sooriyarachchi; Clive Bowman
Sequential genome-wide association studies for monitoring adverse events in the clinical evaluation of new drugs.
Statistics in medicine 2006;25(18):3081-92.
2006: Yinghui Zhou; Roshini Sooriyarachchi; Elisa Bonvini; John W Stevens
Bayesian decision procedures for binary and continuous bivariate dose-escalation studies.
Pharmaceutical statistics 2006;5(2):125-33.
2006: Roshini Sooriyarachchi; Yinghui Zhou; adrian mander; Sally Ritchie; Antony Sabin; Andrew Wright
An evaluation of Bayesian designs for dose-escalation studies in healthy volunteers.
Statistics in medicine 2006;25(3):433-45.
2006: Roshini Sooriyarachchi; Yinghui Zhou; John Stevens; Graham Blakey; Jim Price; Joanna Leadbetter
Bayesian decision procedures for dose-escalation based on evidence of undesirable events and therapeutic benefit.
Statistics in medicine 2006;25(1):37-53.
2004: Roshini Sooriyarachchi; Yinghui Zhou; John Stevens; Graham Blakey
An evaluation of a bayesian method of dose escalation based on bivariate binary responses.
Journal of biopharmaceutical statistics 2004;14(4):969-83.
2004: Yinghui Zhou
Choice of designs and doses for early phase trials.
Fundamental & clinical pharmacology 2004;18(3):373-8.
2001: Roshini Sooriyarachchi; Yinghui Zhou; Nigel Stallard; Susan Todd; Anne Whitehead
Learning from previous responses in phase I dose-escalation studies.
British journal of clinical pharmacology 2001;52(1):1-7.