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Edward Brown

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Kantham Lakshmi; Quinn Steven J; Egbuna Ogo I; Baxi Khanjan; Butters Robert; Pang Jian L; Pollak Martin R; Goltzman David; Brown Edward M
The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion.
Mun H-C; Brennan S C; Delbridge L; Wilkinson M; Brown E M; Conigrave A D
Adenomatous human parathyroid cells exhibit impaired sensitivity to L-amino acids.
Brown Edward M
Anti-parathyroid and anti-calcium sensing receptor antibodies in autoimmune hypoparathyroidism.

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All Publications

2009: Kantham Lakshmi; Quinn Steven J; Egbuna Ogo I; Baxi Khanjan; Butters Robert; Pang Jian L; Pollak Martin R; Goltzman David; Brown Edward M
The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion.
American journal of physiology. Endocrinology and metabolism 2009;297(4):E915-23.
2009: Mun H-C; Brennan S C; Delbridge L; Wilkinson M; Brown E M; Conigrave A D
Adenomatous human parathyroid cells exhibit impaired sensitivity to L-amino acids.
The Journal of clinical endocrinology and metabolism 2009;94(9):3567-74.
2009: Brown Edward M
Anti-parathyroid and anti-calcium sensing receptor antibodies in autoimmune hypoparathyroidism.
Endocrinology and metabolism clinics of North America 2009;38(2):437-45, x.
2009: Hurtel-Lemaire Anne S; Mentaverri Romuald; Caudrillier Axelle; Cournarie Fabienne; Wattel Alice; Kamel Said; Terwilliger Ernest F; Brown Edward M; Brazier Michel
The calcium-sensing receptor is involved in strontium ranelate-induced osteoclast apoptosis. New insights into the associated signaling pathways.
The Journal of biological chemistry 2009;284(1):575-84.
2008: Egbuna Ogo I; Brown Edward M
Hypercalcaemic and hypocalcaemic conditions due to calcium-sensing receptor mutations.
Best practice & research. Clinical rheumatology 2008;22(1):129-48.
2008: Brown Edward M; Lian Jane B
New insights in bone biology: unmasking skeletal effects of the extracellular calcium-sensing receptor.
Science signaling 2008;1(35):pe40.
2008: Conigrave A D; Brown E M; Rizzoli R
Dietary protein and bone health: roles of amino acid-sensing receptors in the control of calcium metabolism and bone homeostasis.
Annual review of nutrition 2008;28():131-55.
2007: Chattopadhyay Naibedya; Quinn Stephen J; Kifor Olga; Ye Chianping; Brown Edward M
The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation.
Biochemical pharmacology 2007;74(3):438-47.
2007: Bandyopadhyay Sanghamitra; Jeong Kyeong-Hoon; Hansen Jacob Tfelt; Vassilev Peter M; Brown Edward M; Chattopadhyay Naibedya
Calcium-sensing receptor stimulates secretion of an interferon-gamma-induced monokine (CXCL10) and monocyte chemoattractant protein-3 in immortalized GnRH neurons.
Journal of neuroscience research 2007;85(4):882-95.
2007: Quinn Stephen J; Kifor Olga; Kifor Imre; Butters Robert R; Brown Edward M
Role of the cytoskeleton in extracellular calcium-regulated PTH release.
Biochemical and biophysical research communications 2007;354(1):8-13.
2007: Brown Edward M
Clinical lessons from the calcium-sensing receptor.
Nature clinical practice. Endocrinology & metabolism 2007;3(2):122-33.
2007: Bianco Suzy D C; Peng Ji-Bin; Takanaga Hitomi; Suzuki Yoshiro; Crescenzi Alessandra; Kos Claudine H; Zhuang Liyan; Freeman Michael R; Gouveia Cecilia H A; Wu Jiangping; Luo Hongyu; Mauro Theodora; Brown Edward M; Hediger Matthias A
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(2):274-85.
2007: Chattopadhyay Naibedya; Jeong Kyeong-Hoon; Yano Shozo; Huang Su; Pang Jian L; Ren Xianghui; Terwilliger Ernest; Kaiser Ursula B; Vassilev Peter M; Pollak Martin R; Brown Edward M
Calcium receptor stimulates chemotaxis and secretion of MCP-1 in GnRH neurons in vitro: potential impact on reduced GnRH neuron population in CaR-null mice.
American journal of physiology. Endocrinology and metabolism 2007;292(2):E523-32.
2007: Brown E M
The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics.
Sub-cellular biochemistry 2007;45():139-67.
2006: Mentaverri R; Yano S; Chattopadhyay N; Petit L; Kifor O; Kamel S; Terwilliger E F; Brazier M; Brown E M
The calcium sensing receptor is directly involved in both osteoclast differentiation and apoptosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2562-4.
2006: LaPlante Janice M; Sun Mei; Falardeau John; Dai Daisy; Brown Edward M; Slaugenhaupt Susan A; Vassilev Peter M
Lysosomal exocytosis is impaired in mucolipidosis type IV.
Molecular genetics and metabolism 2006;89(4):339-48.
2006: Conigrave Arthur D; Brown Edward M
Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(5):G753-61.
2006: Smajilovic Sanela; Hansen Jakob Lerche; Christoffersen Tue E H; Lewin Ewa; Sheikh Søren P; Terwilliger E F; Brown Edward M; Haunso Stig; Tfelt-Hansen Jacob
Extracellular calcium sensing in rat aortic vascular smooth muscle cells.
Biochemical and biophysical research communications 2006;348(4):1215-23.
2006: Adams Gregor B; Chabner Karissa T; Alley Ian R; Olson Douglas P; Szczepiorkowski Zbigniew M; Poznansky Mark C; Kos Claudine H; Pollak Martin R; Brown Edward M; Scadden David T
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor.
Nature 2006;439(7076):599-603.
2005: Tfelt-Hansen Jacob; Yano Shozo; John Macleod R; Smajilovic Sanela; Chattopadhyay Naibedya; Brown Edward M
High calcium activates the EGF receptor potentially through the calcium-sensing receptor in Leydig cancer cells.
Growth factors (Chur, Switzerland) 2005;23(2):117-23.
2005: Tfelt-Hansen Jacob; Ferreira Ana; Yano Shozo; Kanuparthi Deephti; Romero Jose R; Brown Edward M; Chattopadhyay Naibedya
Calcium-sensing receptor activation induces nitric oxide production in H-500 Leydig cancer cells.
American journal of physiology. Endocrinology and metabolism 2005;288(6):E1206-13.
2005: Yano Shozo; Mentaverri Romuald; Kanuparthi Deepthi; Bandyopadhyay Sanghamitra; Rivera Alicia; Brown Edward M; Chattopadhyay Naibedya
Functional expression of beta-chemokine receptors in osteoblasts: role of regulated upon activation, normal T cell expressed and secreted (RANTES) in osteoblasts and regulation of its secretion by osteoblasts and osteoclasts.
Endocrinology 2005;146(5):2324-35.
2004: Brown E M; Chattopadhyay N; Yano S
Calcium-sensing receptors in bone cells.
Journal of musculoskeletal & neuronal interactions 2004;4(4):412-3.
2004: LaPlante Janice M; Ye C P; Quinn Stephen J; Goldin Ehud; Brown Edward M; Slaugenhaupt Susan A; Vassilev Peter M
Functional links between mucolipin-1 and Ca2+-dependent membrane trafficking in mucolipidosis IV.
Biochemical and biophysical research communications 2004;322(4):1384-91.
2004: Yano Shozo; Macleod R John; Chattopadhyay Naibedya; Tfelt-Hansen Jacob; Kifor Olga; Butters Robert R; Brown Edward M
Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: role of epidermal growth factor receptor transactivation.
Bone 2004;35(3):664-72.
2004: Conigrave Arthur D; Mun Hee-Chang; Delbridge Leigh; Quinn Stephen J; Wilkinson Margaret; Brown Edward M
L-amino acids regulate parathyroid hormone secretion.
The Journal of biological chemistry 2004;279(37):38151-9.
2004: Quinn Stephen J; Bai Mei; Brown Edward M
pH Sensing by the calcium-sensing receptor.
The Journal of biological chemistry 2004;279(36):37241-9.
2004: Tfelt-Hansen Jacob; Yano Shozo; Bandyopadhyay Sanghamitra; Carroll Rona; Brown Edward M; Chattopadhyay Naibedya
Expression of pituitary tumor transforming gene (PTTG) and its binding protein in human astrocytes and astrocytoma cells: function and regulation of PTTG in U87 astrocytoma cells.
Endocrinology 2004;145(9):4222-31.
2004: MacLeod R John; Yano S; Chattopadhyay N; Brown E M
Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism.
Biochemical and biophysical research communications 2004;320(2):455-60.
2004: Chattopadhyay Naibedya; Yano Shozo; Tfelt-Hansen Jacob; Rooney Paul; Kanuparthi Deepthi; Bandyopadhyay Sanghamitra; Ren Xianghui; Terwilliger Ernest; Brown Edward M
Mitogenic action of calcium-sensing receptor on rat calvarial osteoblasts.
Endocrinology 2004;145(7):3451-62.
2004: Tfelt-Hansen J; Chattopadhyay N; Yano S; Kanuparthi D; Rooney P; Schwarz P; Brown E M
Calcium-sensing receptor induces proliferation through p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase but not extracellularly regulated kinase in a model of humoral hypercalcemia of malignancy.
Endocrinology 2004;145(3):1211-7.
2004: Chattopadhyay Naibedya; T-Felt Hansen Jacob; Godbole Madan M; Brown Edward M
Transforming growth factor beta receptor family ligands inhibit hepatocyte growth factor synthesis and secretion from astrocytoma cells.
Brain research. Molecular brain research 2004;121(1-2):146-50.
2004: Kifor Olga; McElduff Aidan; LeBoff Meryl S; Moore Francis D; Butters Robert; Gao Ping; Cantor Thomas L; Kifor Imre; Brown Edward M
Activating antibodies to the calcium-sensing receptor in two patients with autoimmune hypoparathyroidism.
The Journal of clinical endocrinology and metabolism 2004;89(2):548-56.
2004: Ye Chian Ping; Yano Shozo; Tfelt-Hansen Jacob; MacLeod R John; Ren Xianghui; Terwilliger Ernest; Brown Edward M; Chattopadhyay Naibedya
Regulation of a Ca2+-activated K+ channel by calcium-sensing receptor involves p38 MAP kinase.
Journal of neuroscience research 2004;75(4):491-8.
2004: Brown Edward M
Calcium sensing by endocrine cells.
Endocrine pathology 2004;15(3):187-219.
2003: Tfelt-Hansen Jacob; Schwarz Peter; Terwilliger Ernest F; Brown Edward M; Chattopadhyay Naibedya
Calcium-sensing receptor induces messenger ribonucleic acid of human securin, pituitary tumor transforming gene, in rat testicular cancer.
Endocrinology 2003;144(12):5188-93.
2003: Kifor Olga; Kifor Imre; Moore Francis D; Butters Robert R; Cantor Thomas; Gao Ping; Brown Edward M
Decreased expression of caveolin-1 and altered regulation of mitogen-activated protein kinase in cultured bovine parathyroid cells and human parathyroid adenomas.
The Journal of clinical endocrinology and metabolism 2003;88(9):4455-64.
2003: Kifor Olga; Kifor Imre; Moore Francis D; Butters Robert R; Brown Edward M
m-Calpain colocalizes with the calcium-sensing receptor (CaR) in caveolae in parathyroid cells and participates in degradation of the CaR.
The Journal of biological chemistry 2003;278(33):31167-76.
2003: Tfelt-Hansen J; MacLeod R J; Chattopadhyay N; Yano S; Quinn S; Ren X; Terwilliger E F; Schwarz P; Brown E M
Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells.
American journal of physiology. Endocrinology and metabolism 2003;285(2):E329-37.
2003: Tfelt-Hansen Jacob; Schwarz Peter; Brown Edward M; Chattopadhyay Naibedya
The calcium-sensing receptor in human disease.
Frontiers in bioscience : a journal and virtual library 2003;8():s377-90.
2003: Nauli Surya M; Alenghat Francis J; Luo Ying; Williams Eric; Vassilev Peter; Li Xiaogang; Elia Andrew E H; Lu Weining; Brown Edward M; Quinn Stephen J; Ingber Donald E; Zhou Jing
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.
Nature genetics 2003;33(2):129-37.
2003: MacLeod R John; Chattopadhyay Naibedya; Brown Edward M
PTHrP stimulated by the calcium-sensing receptor requires MAP kinase activation.
American journal of physiology. Endocrinology and metabolism 2003;284(2):E435-42.
2003: Kifor Olga; Moore Francis D; Delaney Miriam; Garber Jeffrey; Hendy Geoffrey N; Butters Robert; Gao Ping; Cantor Thomas L; Kifor Imre; Brown Edward M; Wysolmerski John
A syndrome of hypocalciuric hypercalcemia caused by autoantibodies directed at the calcium-sensing receptor.
The Journal of clinical endocrinology and metabolism 2003;88(1):60-72.
2003: Chattopadhyay Naibedya; MacLeod R J; Tfelt-Hansen Jacob; Brown Edward M
1alpha,25(OH)2-vitamin D3 inhibits HGF synthesis and secretion from MG-63 human osteosarcoma cells.
American journal of physiology. Endocrinology and metabolism 2003;284(1):E219-27.
2003: Brown Edward M
Is the calcium receptor a molecular target for the actions of strontium on bone?
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2003;14 Suppl 3():S25-34.
2002: LaPlante Janice M; Falardeau John; Sun Mei; Kanazirska Marie; Brown Edward M; Slaugenhaupt Susan A; Vassilev Peter M
Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway.
FEBS letters 2002;532(1-2):183-7.
2002: Conigrave A D; Franks A H; Brown E M; Quinn S J
L-amino acid sensing by the calcium-sensing receptor: a general mechanism for coupling protein and calcium metabolism?
European journal of clinical nutrition 2002;56(11):1072-80.
2002: Brown Edward M
The pathophysiology of primary hyperparathyroidism.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17 Suppl 2():N24-9.
2002: Zhang Zaixiang; Qiu Weiying; Quinn Stephen J; Conigrave Arthur D; Brown Edward M; Bai Mei
Three adjacent serines in the extracellular domains of the CaR are required for L-amino acid-mediated potentiation of receptor function.
The Journal of biological chemistry 2002;277(37):33727-35.
2002: Kifor Olga; Kifor Imre; Brown Edward M
Signal transduction in the parathyroid.
Current opinion in nephrology and hypertension 2002;11(4):397-402.
2002: Chattopadhyay Naibedya; Tfelt-Hansen Jacob; Brown Edward M
PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells.
Brain research. Molecular brain research 2002;102(1-2):73-82.
2002: Bradbury R A; Cropley J; Kifor O; Lovicu F J; de Iongh R U; Kable E; Brown E M; Seely E W; Peat B B; Conigrave A D
Localization of the extracellular Ca(2+)-sensing receptor in the human placenta.
Placenta 2002;23(2-3):192-200.
2002: Brown Edward M
The calcium-sensing receptor (CaR) and its disorders.
Hormones (Athens, Greece) 2002;1(1):10-21.
2001: Sanders J L; Chattopadhyay N; Kifor O; Yamaguchi T; Brown E M
Ca(2+)-sensing receptor expression and PTHrP secretion in PC-3 human prostate cancer cells.
American journal of physiology. Endocrinology and metabolism 2001;281(6):E1267-74.
2001: Vassilev P M; Peng J B; Hediger M A; Brown E M
Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.
The Journal of membrane biology 2001;184(2):113-20.
2001: Caroppo R; Gerbino A; Debellis L; Kifor O; Soybel D I; Brown E M; Hofer A M; Curci S
Asymmetrical, agonist-induced fluctuations in local extracellular [Ca(2+)] in intact polarized epithelia.
The EMBO journal 2001;20(22):6316-26.
2001: Hjälm G; MacLeod R J; Kifor O; Chattopadhyay N; Brown E M
Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase.
The Journal of biological chemistry 2001;276(37):34880-7.
2001: Chattopadhyay N; Brown E M
Retinoic acid receptors are expressed in human primary astrocytes and their agonists inhibit parathyroid hormone-related peptide expression and secretion.
Brain research. Molecular brain research 2001;92(1-2):172-6.
2001: Chen X Z; Segal Y; Basora N; Guo L; Peng J B; Babakhanlou H; Vassilev P M; Brown E M; Hediger M A; Zhou J
Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X.
Biochemical and biophysical research communications 2001;282(5):1251-6.
2001: Vassilev P M; Guo L; Chen X Z; Segal Y; Peng J B; Basora N; Babakhanlou H; Cruger G; Kanazirska M; Ye Cp; Brown E M; Hediger M A; Zhou J
Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease.
Biochemical and biophysical research communications 2001;282(1):341-50.
2001: Chattopadhyay N; Butters R R; Brown E M
Agonists of the retinoic acid- and retinoid X-receptors inhibit hepatocyte growth factor secretion and expression in U87 human astrocytoma cells.
Brain research. Molecular brain research 2001;87(1):100-8.
2001: Kifor O; MacLeod R J; Diaz R; Bai M; Yamaguchi T; Yao T; Kifor I; Brown E M
Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells.
American journal of physiology. Renal physiology 2001;280(2):F291-302.
2001: Yamaguchi T; Chattopadhyay N; Kifor O; Ye C; Vassilev P M; Sanders J L; Brown E M
Expression of extracellular calcium-sensing receptor in human osteoblastic MG-63 cell line.
American journal of physiology. Cell physiology 2001;280(2):C382-93.
2001: Zhang Z; Sun S; Quinn S J; Brown E M; Bai M
The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions.
The Journal of biological chemistry 2001;276(7):5316-22.
2001: Vassilev P M; Peng J B; Johnson J; Hediger M A; Brown E M
Inhibition of CaT1 channel activity by a noncompetitive IP3 antagonist.
Biochemical and biophysical research communications 2001;280(1):145-50.
2001: Brown E M; MacLeod R J
Extracellular calcium sensing and extracellular calcium signaling.
Physiological reviews 2001;81(1):239-297.
2000: Yamaguchi T; Chattopadhyay N; Kifor O; Sanders J L; Brown E M
Activation of p42/44 and p38 mitogen-activated protein kinases by extracellular calcium-sensing receptor agonists induces mitogenic responses in the mouse osteoblastic MC3T3-E1 cell line.
Biochemical and biophysical research communications 2000;279(2):363-8.
2000: Sanders J L; Chattopadhyay N; Kifor O; Yamaguchi T; Butters R R; Brown E M
Extracellular calcium-sensing receptor expression and its potential role in regulating parathyroid hormone-related peptide secretion in human breast cancer cell lines.
Endocrinology 2000;141(12):4357-64.
2000: Conigrave A D; Quinn S J; Brown E M
Cooperative multi-modal sensing and therapeutic implications of the extracellular Ca(2+) sensing receptor.
Trends in pharmacological sciences 2000;21(10):401-7.
2000: Ye C; Chattopadhyay N; Brown E M; Vassilev P M
Defective extracellular calcium (Ca(o))-sensing receptor (CaR)-mediated stimulation of a Ca(2+)-activated potassium channel in glioblastoma cells transfected with a dominant negative CaR.
Brain research. Molecular brain research 2000;80(2):177-87.
2000: Brown E M
Familial hypocalciuric hypercalcemia and other disorders with resistance to extracellular calcium.
Endocrinology and metabolism clinics of North America 2000;29(3):503-22.
2000: Chattopadhyay N; Evliyaoglu C; Heese O; Carroll R; Sanders J; Black P; Brown E M
Regulation of secretion of PTHrP by Ca(2+)-sensing receptor in human astrocytes, astrocytomas, and meningiomas.
American journal of physiology. Cell physiology 2000;279(3):C691-9.
2000: Hofer A M; Curci S; Doble M A; Brown E M; Soybel D I
Intercellular communication mediated by the extracellular calcium-sensing receptor.
Nature cell biology 2000;2(7):392-8.
2000: Ye C P; Yamaguchi T; Chattopadhyay N; Sanders J L; Vassilev P M; Brown E M
Extracellular calcium-sensing-receptor (CaR)-mediated opening of an outward K(+) channel in murine MC3T3-E1 osteoblastic cells: evidence for expression of a functional CaR.
Bone 2000;27(1):21-7.
2000: Chattopadhyay N; Brown E M
Cellular "sensing" of extracellular calcium (Ca(2+)(o)): emerging roles in regulating diverse physiological functions.
Cellular signalling 2000;12(6):361-6.
2000: Olszak I T; Poznansky M C; Evans R H; Olson D; Kos C; Pollak M R; Brown E M; Scadden D T
Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo.
The Journal of clinical investigation 2000;105(9):1299-305.
2000: Yamaguchi T; Ye C; Chattopadhyay N; Sanders J L; Vassilev P M; Brown E M
Enhanced expression of extracellular calcium sensing receptor in monocyte-differentiated versus undifferentiated HL-60 cells: potential role in regulation of a nonselective cation channel.
Calcified tissue international 2000;66(5):375-82.
2000: Conigrave A D; Quinn S J; Brown E M
L-amino acid sensing by the extracellular Ca2+-sensing receptor.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4814-9.
2000: Haden S T; Brown E M; Hurwitz S; Scott J; El-Hajj Fuleihan G
The effects of age and gender on parathyroid hormone dynamics.
Clinical endocrinology 2000;52(3):329-38.
2000: Sanders J L; Chattopadhyay N; Kifor O; Yamaguchi T; Brown E M
Extracellular calcium-sensing receptor (CaR) expression and its potential role in parathyroid hormone-related peptide (PTHrP) secretion in the H-500 rat Leydig cell model of humoral hypercalcemia of malignancy.
Biochemical and biophysical research communications 2000;269(2):427-32.
2000: Brown E M
G protein-coupled, extracellular Ca2+ (Ca2+(o))-sensing receptor enables Ca2+(o) to function as a versatile extracellular first messenger.
Cell biochemistry and biophysics 2000;33(1):63-95.
2000: Brown E M
The extracellular Ca2+-sensing receptor: central mediator of systemic calcium homeostasis.
Annual review of nutrition 2000;20():507-33.
2000: Yamaguchi T; Chattopadhyay N; Brown E M
G protein-coupled extracellular Ca2+ (Ca2+o)-sensing receptor (CaR): roles in cell signaling and control of diverse cellular functions.
Advances in pharmacology (San Diego, Calif.) 2000;47():209-53.
1999: Chattopadhyay N; Ye C P; Yamaguchi T; Kerner R; Vassilev P M; Brown E M
Extracellular calcium-sensing receptor induces cellular proliferation and activation of a nonselective cation channel in U373 human astrocytoma cells.
Brain research 1999;851(1-2):116-24.
1999: Chen X Z; Vassilev P M; Basora N; Peng J B; Nomura H; Segal Y; Brown E M; Reeders S T; Hediger M A; Zhou J
Polycystin-L is a calcium-regulated cation channel permeable to calcium ions.
Nature 1999;401(6751):383-6.
1999: Chattopadhyay N; Ye C; Yamaguchi T; Nakai M; Kifor O; Vassilev P M; Nishimura R N; Brown E M
The extracellular calcium-sensing receptor is expressed in rat microglia and modulates an outward K+ channel.
Journal of neurochemistry 1999;72(5):1915-22.
1999: Chattopadhyay N; Ye C P; Yamaguchi T; Vassilev P M; Brown E M
Evidence for extracellular calcium-sensing receptor mediated opening of an outward K+ channel in a human astrocytoma cell line (U87).
Glia 1999;26(1):64-72.
1999: Bai M; Trivedi S; Kifor O; Quinn S J; Brown E M
Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2834-9.
1999: Brown E M
Physiology and pathophysiology of the extracellular calcium-sensing receptor.
The American journal of medicine 1999;106(2):238-53.
1999: Porter L; Conlin P R; Scott J; Brown E M; El-Hajj Fuleihan G
Calcium modulation of the renin-aldosterone axis.
Journal of endocrinological investigation 1999;22(2):115-21.
1999: Haden S T; Brown E M; Stoll A L; Scott J; Fuleihan G E
The effect of lithium on calcium-induced changes in adrenocorticotrophin levels.
The Journal of clinical endocrinology and metabolism 1999;84(1):198-200.
1999: Cheng I; Qureshi I; Chattopadhyay N; Qureshi A; Butters R R; Hall A E; Cima R R; Rogers K V; Hebert S C; Geibel J P; Brown E M; Soybel D I
Expression of an extracellular calcium-sensing receptor in rat stomach.
Gastroenterology 1999;116(1):118-26.
1999: Brown E M; Vassilev P M; Quinn S; Hebert S C
G-protein-coupled, extracellular Ca(2+)-sensing receptor: a versatile regulator of diverse cellular functions.
Vitamins and hormones 1999;55():1-71.
1998: Chattopadhyay N; Ye C P; Yamaguchi T; Kifor O; Vassilev P M; Nishimura R; Brown E M
Extracellular calcium-sensing receptor in rat oligodendrocytes: expression and potential role in regulation of cellular proliferation and an outward K+ channel.
Glia 1998;24(4):449-58.
1998: Chattopadhyay N; Yamaguchi T; Brown E M
Ca(2+) receptor from brain to gut: common stimulus, diverse actions.
Trends in endocrinology and metabolism: TEM 1998;9(9):354-9.
1998: Yamaguchi T; Chattopadhyay N; Kifor O; Butters R R; Sugimoto T; Brown E M
Mouse osteoblastic cell line (MC3T3-E1) expresses extracellular calcium (Ca2+o)-sensing receptor and its agonists stimulate chemotaxis and proliferation of MC3T3-E1 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(10):1530-8.
1998: Yamaguchi T; Kifor O; Chattopadhyay N; Bai M; Brown E M
Extracellular calcium (Ca2+o)-sensing receptor in a mouse monocyte-macrophage cell line (J774): potential mediator of the actions of Ca2+o on the function of J774 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(9):1390-7.
1998: Bai M; Trivedi S; Brown E M
Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells.
The Journal of biological chemistry 1998;273(36):23605-10.
1998: Kifor O; Diaz R; Butters R; Kifor I; Brown E M
The calcium-sensing receptor is localized in caveolin-rich plasma membrane domains of bovine parathyroid cells.
The Journal of biological chemistry 1998;273(34):21708-13.
1998: Bai M; Trivedi S; Lane C R; Yang Y; Quinn S J; Brown E M
Protein kinase C phosphorylation of threonine at position 888 in Ca2+o-sensing receptor (CaR) inhibits coupling to Ca2+ store release.
The Journal of biological chemistry 1998;273(33):21267-75.
1998: Yamaguchi T; Chattopadhyay N; Kifor O; Brown E M
Extracellular calcium (Ca2+(o))-sensing receptor in a murine bone marrow-derived stromal cell line (ST2): potential mediator of the actions of Ca2+(o) on the function of ST2 cells.
Endocrinology 1998;139(8):3561-8.
1998: el-Hajj Fuleihan G; Seifter J; Scott J; Brown E M
Calcium-regulated renal calcium handling in healthy men: relationship to sodium handling.
The Journal of clinical endocrinology and metabolism 1998;83(7):2366-72.
1998: Yamaguchi T; Olozak I; Chattopadhyay N; Butters R R; Kifor O; Scadden D T; Brown E M
Expression of extracellular calcium (Ca2+o)-sensing receptor in human peripheral blood monocytes.
Biochemical and biophysical research communications 1998;246(2):501-6.
1998: Bradbury R A; Sunn K L; Crossley M; Bai M; Brown E M; Delbridge L; Conigrave A D
Expression of the parathyroid Ca(2+)-sensing receptor in cytotrophoblasts from human term placenta.
The Journal of endocrinology 1998;156(3):425-30.
1998: Yamaguchi T; Kifor O; Chattopadhyay N; Brown E M
Expression of extracellular calcium (Ca2 + o)-sensing receptor in the clonal osteoblast-like cell lines, UMR-106 and SAOS-2.
Biochemical and biophysical research communications 1998;243(3):753-7.
1998: Cheng I; Klingensmith M E; Chattopadhyay N; Kifor O; Butters R R; Soybel D I; Brown E M
Identification and localization of the extracellular calcium-sensing receptor in human breast.
The Journal of clinical endocrinology and metabolism 1998;83(2):703-7.
1998: Chattopadhyay N; Cheng I; Rogers K; Riccardi D; Hall A; Diaz R; Hebert S C; Soybel D I; Brown E M
Identification and localization of extracellular Ca(2+)-sensing receptor in rat intestine.
The American journal of physiology 1998;274(1 Pt 1):G122-30.
1998: Brown E M; Chattopadhyay N; Vassilev P M; Hebert S C
The calcium-sensing receptor (CaR) permits Ca2+ to function as a versatile extracellular first messenger.
Recent progress in hormone research 1998;53():257-80; discussion 280-1.
1998: Brown E M; Pollak M; Hebert S C
The extracellular calcium-sensing receptor: its role in health and disease.
Annual review of medicine 1998;49():15-29.
1997: House M G; Kohlmeier L; Chattopadhyay N; Kifor O; Yamaguchi T; Leboff M S; Glowacki J; Brown E M
Expression of an extracellular calcium-sensing receptor in human and mouse bone marrow cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(12):1959-70.
1997: Cima R R; Cheng I; Klingensmith M E; Chattopadhyay N; Kifor O; Hebert S C; Brown E M; Soybel D I
Identification and functional assay of an extracellular calcium-sensing receptor in Necturus gastric mucosa.
The American journal of physiology 1997;273(5 Pt 1):G1051-60.
1997: Nielsen P K; Rasmussen A K; Butters R; Feldt-Rasmussen U; Bendtzen K; Diaz R; Brown E M; Olgaard K
Inhibition of PTH secretion by interleukin-1 beta in bovine parathyroid glands in vitro is associated with an up-regulation of the calcium-sensing receptor mRNA.
Biochemical and biophysical research communications 1997;238(3):880-5.
1997: Diaz R; Hurwitz S; Chattopadhyay N; Pines M; Yang Y; Kifor O; Einat M S; Butters R; Hebert S C; Brown E M
Cloning, expression, and tissue localization of the calcium-sensing receptor in chicken (Gallus domesticus).
The American journal of physiology 1997;273(3 Pt 2):R1008-16.
1997: Autry C P; Kifor O; Brown E M; Fuller F H; Rogers K V; Halloran B P
Ca2+ receptor mRNA and protein increase in the rat parathyroid gland with advancing age.
The Journal of endocrinology 1997;153(3):437-44.
1997: Chattopadhyay N; Legradi G; Bai M; Kifor O; Ye C; Vassilev P M; Brown E M; Lechan R M
Calcium-sensing receptor in the rat hippocampus: a developmental study.
Brain research. Developmental brain research 1997;100(1):13-21.
1997: Kifor O; Diaz R; Butters R; Brown E M
The Ca2+-sensing receptor (CaR) activates phospholipases C, A2, and D in bovine parathyroid and CaR-transfected, human embryonic kidney (HEK293) cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(5):715-25.
1997: Vassilev P M; Mitchel J; Vassilev M; Kanazirska M; Brown E M
Assessment of frequency-dependent alterations in the level of extracellular Ca2+ in the synaptic cleft.
Biophysical journal 1997;72(5):2103-16.
1997: Vassilev P M; Ho-Pao C L; Kanazirska M P; Ye C; Hong K; Seidman C E; Seidman J G; Brown E M
Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons.
Neuroreport 1997;8(6):1411-6.
1997: Chattopadhyay N; Ye C; Singh D P; Kifor O; Vassilev P M; Shinohara T; Chylack L T; Brown E M
Expression of extracellular calcium-sensing receptor by human lens epithelial cells.
Biochemical and biophysical research communications 1997;233(3):801-5.
1997: Bai M; Janicic N; Trivedi S; Quinn S J; Cole D E; Brown E M; Hendy G N
Markedly reduced activity of mutant calcium-sensing receptor with an inserted Alu element from a kindred with familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.
The Journal of clinical investigation 1997;99(8):1917-25.
1997: Brown E M; Hebert S C
Calcium-receptor-regulated parathyroid and renal function.
Bone 1997;20(4):303-9.
1997: Butters R R; Chattopadhyay N; Nielsen P; Smith C P; Mithal A; Kifor O; Bai M; Quinn S; Goldsmith P; Hurwitz S; Krapcho K; Busby J; Brown E M
Cloning and characterization of a calcium-sensing receptor from the hypercalcemic New Zealand white rabbit reveals unaltered responsiveness to extracellular calcium.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(4):568-79.
1997: Ye C; Ho-Pao C L; Kanazirska M; Quinn S; Rogers K; Seidman C E; Seidman J G; Brown E M; Vassilev P M
Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.
Journal of neuroscience research 1997;47(5):547-54.
1997: Hebert S C; Brown E M; Harris H W
Role of the Ca(2+)-sensing receptor in divalent mineral ion homeostasis.
The Journal of experimental biology 1997;200(Pt 2):295-302.
1997: Rogers K V; Dunn C K; Hebert S C; Brown E M
Localization of calcium receptor mRNA in the adult rat central nervous system by in situ hybridization.
Brain research 1997;744(1):47-56.
1997: Vassilev P M; Kanazirska M P; Ye C; Francis J; Hong K; Brown E M
A flickery block of a K+ channel mediated by extracellular Ca2+ and other agonists of the Ca2+-sensing receptors in dispersed bovine parathyroid cells.
Biochemical and biophysical research communications 1997;230(3):616-23.
1997: Bai M; Pearce S H; Kifor O; Trivedi S; Stauffer U G; Thakker R V; Brown E M; Steinmann B
In vivo and in vitro characterization of neonatal hyperparathyroidism resulting from a de novo, heterozygous mutation in the Ca2+-sensing receptor gene: normal maternal calcium homeostasis as a cause of secondary hyperparathyroidism in familial benign hypocalciuric hypercalcemia.
The Journal of clinical investigation 1997;99(1):88-96.
1997: el-Hajj Fuleihan G; Klerman E B; Brown E N; Choe Y; Brown E M; Czeisler C A
The parathyroid hormone circadian rhythm is truly endogenous--a general clinical research center study.
The Journal of clinical endocrinology and metabolism 1997;82(1):281-6.
1997: Brown E M
Mutations in the calcium-sensing receptor and their clinical implications.
Hormone research 1997;48(5):199-208.
1997: Ye C; Ho-Pao C L; Kanazirska M; Quinn S; Seidman C E; Seidman J G; Brown E M; Vassilev P M
Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene.
Brain research bulletin 1997;44(1):75-84.
1996: Riccardi D; Lee W S; Lee K; Segre G V; Brown E M; Hebert S C
Localization of the extracellular Ca(2+)-sensing receptor and PTH/PTHrP receptor in rat kidney.
The American journal of physiology 1996;271(4 Pt 2):F951-6.
1996: Pearce S H; Bai M; Quinn S J; Kifor O; Brown E M; Thakker R V
Functional characterization of calcium-sensing receptor mutations expressed in human embryonic kidney cells.
The Journal of clinical investigation 1996;98(8):1860-6.
1996: Pearce S H; Williamson C; Kifor O; Bai M; Coulthard M G; Davies M; Lewis-Barned N; McCredie D; Powell H; Kendall-Taylor P; Brown E M; Thakker R V
A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor.
The New England journal of medicine 1996;335(15):1115-22.
1996: Chattopadhyay N; Baum M; Bai M; Riccardi D; Hebert S C; Harris H W; Brown E M
Ontogeny of the extracellular calcium-sensing receptor in rat kidney.
The American journal of physiology 1996;271(3 Pt 2):F736-43.
1996: Ye C; Rogers K; Bai M; Quinn S J; Brown E M; Vassilev P M
Agonists of the Ca(2+)-sensing receptor (CaR) activate nonselective cation channels in HEK293 cells stably transfected with the human CaR.
Biochemical and biophysical research communications 1996;226(2):572-9.
1996: Brown E M; Hebert S C
The First Annual Bayard D. Catherwood Memorial Lecture. Ca2+-receptor-mediated regulation of parathyroid and renal function.
The American journal of the medical sciences 1996;312(3):99-109.
1996: Bai M; Quinn S; Trivedi S; Kifor O; Pearce S H; Pollak M R; Krapcho K; Hebert S C; Brown E M
Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor.
The Journal of biological chemistry 1996;271(32):19537-45.
1996: Ye C; Kanazirska M; Quinn S; Brown E M; Vassilev P M
Modulation by polycationic Ca(2+)-sensing receptor agonists of nonselective cation channels in rat hippocampal neurons.
Biochemical and biophysical research communications 1996;224(1):271-80.
1996: Pearce S H; Brown E M
Disorders of calcium ion sensing.
The Journal of clinical endocrinology and metabolism 1996;81(6):2030-5.
1996: Pollak M R; Seidman C E; Brown E M
Three inherited disorders of calcium sensing.
Medicine 1996;75(3):115-23.
1996: Emanuel R L; Adler G K; Kifor O; Quinn S J; Fuller F; Krapcho K; Brown E M
Calcium-sensing receptor expression and regulation by extracellular calcium in the AtT-20 pituitary cell line.
Molecular endocrinology (Baltimore, Md.) 1996;10(5):555-65.
1996: Brown E M; Hebert S C
A cloned extracellular Ca(2+)-sensing receptor: molecular mediator of the actions of extracellular Ca2+ on parathyroid and kidney cells?
Kidney international 1996;49(4):1042-6.
1996: Kifor O; Moore F D; Wang P; Goldstein M; Vassilev P; Kifor I; Hebert S C; Brown E M
Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism.
The Journal of clinical endocrinology and metabolism 1996;81(4):1598-606.
1996: Fuleihan G E; Brown E M; Gleason R; Scott J; Adler G K
Calcium modulation of adrenocorticotropin levels in women--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1996;81(3):932-6.
1996: Hebert S C; Brown E M
The scent of an ion: calcium-sensing and its roles in health and disease.
Current opinion in nephrology and hypertension 1996;5(1):45-53.
1996: Brown E M; Segre G V; Goldring S R
Serpentine receptors for parathyroid hormone, calcitonin and extracellular calcium ions.
Baillière's clinical endocrinology and metabolism 1996;10(1):123-61.
1996: Hebert S C; Pollak M; Riccardi D; Brown E M
A Ca(2+)-sensing receptor: from physiology to inherited disorders of calcium homeostasis.
Advances in nephrology from the Necker Hospital 1996;25():245-55.
1995: Brown E M; Vassilev P M; Hebert S C
Calcium ions as extracellular messengers.
Cell 1995;83(5):679-82.
1995: Ho C; Conner D A; Pollak M R; Ladd D J; Kifor O; Warren H B; Brown E M; Seidman J G; Seidman C E
A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.
Nature genetics 1995;11(4):389-94.
1995: Garrett J E; Tamir H; Kifor O; Simin R T; Rogers K V; Mithal A; Gagel R F; Brown E M
Calcitonin-secreting cells of the thyroid express an extracellular calcium receptor gene.
Endocrinology 1995;136(11):5202-11.
1995: Brown E M; Pollak M; Chou Y H; Seidman C E; Seidman J G; Hebert S C
Cloning and functional characterization of extracellular Ca(2+)-sensing receptors from parathyroid and kidney.
Bone 1995;17(2 Suppl):7S-11S.
1995: Hebert S C; Brown E M
The extracellular calcium receptor.
Current opinion in cell biology 1995;7(4):484-92.
1995: Brown E M; Pollak M; Seidman C E; Seidman J G; Chou Y H; Riccardi D; Hebert S C
Calcium-ion-sensing cell-surface receptors.
The New England journal of medicine 1995;333(4):234-40.
1995: Mithal A; Kifor O; Kifor I; Vassilev P; Butters R; Krapcho K; Simin R; Fuller F; Hebert S C; Brown E M
The reduced responsiveness of cultured bovine parathyroid cells to extracellular Ca2+ is associated with marked reduction in the expression of extracellular Ca(2+)-sensing receptor messenger ribonucleic acid and protein.
Endocrinology 1995;136(7):3087-92.
1995: Brown E M; Pollak M; Chou Y H; Seidman C E; Seidman J G; Hebert S C
The cloning of extracellular Ca(2+)-sensing receptors from parathyroid and kidney: molecular mechanisms of extracellular Ca(2+)-sensing.
The Journal of nutrition 1995;125(7 Suppl):1965S-1970S.
1995: Garrett J E; Capuano I V; Hammerland L G; Hung B C; Brown E M; Hebert S C; Nemeth E F; Fuller F
Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs.
The Journal of biological chemistry 1995;270(21):12919-25.
1995: Brown E M; Pollak M; Hebert S C
Molecular mechanisms underlying the sensing of extracellular Ca2+ by parathyroid and kidney cells.
European journal of endocrinology / European Federation of Endocrine Societies 1995;132(5):523-31.
1995: Kanazirska M P; Vassilev P M; Ye C P; Francis J E; Brown E M
Intracellular Ca(2+)-activated K+ channels modulated by variations in extracellular Ca2+ in dispersed bovine parathyroid cells.
Endocrinology 1995;136(5):2238-43.
1995: Brown E M; Pollak M; Hebert S C
Sensing of extracellular Ca2+ by parathyroid and kidney cells: cloning and characterization of an extracellular Ca(2+)-sensing receptor.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1995;25(3):506-13.
1995: Rogers K V; Dunn C K; Conklin R L; Hadfield S; Petty B A; Brown E M; Hebert S C; Nemeth E F; Fox J
Calcium receptor messenger ribonucleic acid levels in the parathyroid glands and kidney of vitamin D-deficient rats are not regulated by plasma calcium or 1,25-dihydroxyvitamin D3.
Endocrinology 1995;136(2):499-504.
1995: Riccardi D; Park J; Lee W S; Gamba G; Brown E M; Hebert S C
Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):131-5.
1994: Fuleihan G E; Gundberg C M; Gleason R; Brown E M; Stromski M E; Grant F D; Conlin P R
Racial differences in parathyroid hormone dynamics.
The Journal of clinical endocrinology and metabolism 1994;79(6):1642-7.
1994: Pollak M R; Brown E M; Estep H L; McLaine P N; Kifor O; Park J; Hebert S C; Seidman C E; Seidman J G
Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation.
Nature genetics 1994;8(3):303-7.
1994: Pollak M R; Chou Y H; Marx S J; Steinmann B; Cole D E; Brandi M L; Papapoulos S E; Menko F H; Hendy G N; Brown E M
Familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Effects of mutant gene dosage on phenotype.
The Journal of clinical investigation 1994;93(3):1108-12.
1994: Brown E M; Pollak M; Riccardi D; Hebert S C
Cloning and characterization of an extracellular Ca(2+)-sensing receptor from parathyroid and kidney: new insights into the physiology and pathophysiology of calcium metabolism.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1994;9(12):1703-6.
1993: Brown E M; Gamba G; Riccardi D; Lombardi M; Butters R; Kifor O; Sun A; Hediger M A; Lytton J; Hebert S C
Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid.
Nature 1993;366(6455):575-80.
1993: Pollak M R; Brown E M; Chou Y H; Hebert S C; Marx S J; Steinmann B; Levi T; Seidman C E; Seidman J G
Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.
Cell 1993;75(7):1297-303.
1993: Brown E M
Mechanisms underlying the regulation of parathyroid hormone secretion in vivo and in vitro.
Current opinion in nephrology and hypertension 1993;2(4):541-51.
1992: Rivkees S A; el-Hajj-Fuleihan G; Brown E M; Crawford J D
Tertiary hyperparathyroidism during high phosphate therapy of familial hypophosphatemic rickets.
The Journal of clinical endocrinology and metabolism 1992;75(6):1514-8.
1992: Kifor O; Kifor I; Brown E M
Effects of high extracellular calcium concentrations on phosphoinositide turnover and inositol phosphate metabolism in dispersed bovine parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(11):1327-36.
1992: el-Hajj Fuleihan G; Brown E M; Curtis K; Berger M J; Berger B M; Gleason R; LeBoff M S
Effect of sequential and daily continuous hormone replacement therapy on indexes of mineral metabolism.
Archives of internal medicine 1992;152(9):1904-9.
1992: Katz C L; Butters R R; Chen C J; Brown E M
Structure-function relationships for the effects of various aminoglycoside antibiotics on dispersed bovine parathyroid cells.
Endocrinology 1992;131(2):903-10.
1992: Seely E W; Wood R J; Brown E M; Graves S W
Lower serum ionized calcium and abnormal calciotropic hormone levels in preeclampsia.
The Journal of clinical endocrinology and metabolism 1992;74(6):1436-40.
1992: Brown E M; Butters R; Katz C; Kifor O; Fuleihan G E
A comparison of the effects of concanavalin-A and tetradecanoylphorbol acetate on the modulation of parathyroid function by extracellular calcium and neomycin in dispersed bovine parathyroid cells.
Endocrinology 1992;130(6):3143-51.
1991: Brown E M; Katz C; Butters R; Kifor O
Polyarginine, polylysine, and protamine mimic the effects of high extracellular calcium concentrations on dispersed bovine parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(11):1217-25.
1991: Fajtova V T; Quinn S J; Brown E M
Cytosolic calcium responses of single rMTC 44-2 cells to stimulation with external calcium and potassium.
The American journal of physiology 1991;261(1 Pt 1):E151-8.
1991: el-Hajj Fuleihan G; Katz C; Kifor O; Gleason R; Brown E M
Effects of the lectin concanavalin-A on the regulation of second messengers and parathyroid hormone release by extracellular Ca2+ in bovine parathyroid cells.
Endocrinology 1991;128(6):2931-6.
1991: Brown E M; Butters R; Katz C; Kifor O
Neomycin mimics the effects of high extracellular calcium concentrations on parathyroid function in dispersed bovine parathyroid cells.
Endocrinology 1991;128(6):3047-54.
1991: Brown E M
Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers.
Physiological reviews 1991;71(2):371-411.
1991: Rubin L P; Posillico J T; Anast C S; Brown E M
Circulating levels of biologically active and immunoreactive intact parathyroid hormone in human newborns.
Pediatric research 1991;29(2):201-7.
1991: Gundberg C M; Grant F D; Conlin P R; Chen C J; Brown E M; Johnson P J; LeBoff M S
Acute changes in serum osteocalcin during induced hypocalcemia in humans.
The Journal of clinical endocrinology and metabolism 1991;72(2):438-43.
1990: Kifor O; Congo D; Brown E M
Phorbol esters modulate the high Ca2(+)-stimulated accumulation of inositol phosphates in bovine parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(10):1003-11.
1990: Brown E M; Fuleihan G el-H; Chen C J; Kifor O
A comparison of the effects of divalent and trivalent cations on parathyroid hormone release, 3',5'-cyclic-adenosine monophosphate accumulation, and the levels of inositol phosphates in bovine parathyroid cells.
Endocrinology 1990;127(3):1064-71.
1990: Grant F D; Conlin P R; Brown E M
Rate and concentration dependence of parathyroid hormone dynamics during stepwise changes in serum ionized calcium in normal humans.
The Journal of clinical endocrinology and metabolism 1990;71(2):370-8.
1990: Leboff M S; Oetting M; Brown E M
Mechanisms underlying the stimulation of PTH release by GppNHp in permeabilized bovine parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(7):683-9.
1990: Chen C J; Brown E M
The diltiazem analog TA-3090 mimics the actions of high extracellular Ca2+ on parathyroid function in dispersed bovine parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(6):581-7.
1990: Brown E M; Chen C J; Kifor O; Leboff M S; el-Hajj G; Fajtova V; Rubin L T
Ca2(+)-sensing, second messengers, and the control of parathyroid hormone secretion.
Cell calcium 1990;11(5):333-7.
1990: el-Hajj Fuleihan G; Brown E M
Effect of the lectin concanavalin-A on calcium-regulated adenosine 3',5'-monophosphate accumulation in bovine parathyroid cells.
Endocrinology 1990;126(4):1996-2002.
1989: Smith S; Swain J; Brown E M; Wyshak G; Albright T; Ravnikar V A; Schiff I
A preliminary report of the short-term effect of carbonated beverage consumption on calcium metabolism in normal women.
Archives of internal medicine 1989;149(11):2517-9.
1989: Warren H B; Lausen N C; Segre G V; el-Hajj G; Brown E M
Regulation of calciotropic hormones in vivo in the New Zealand white rabbit.
Endocrinology 1989;125(5):2683-90.
1989: el-Hajj Fuleihan G; Chen C J; Rivkees S A; Marynick S P; Stock J; Pallotta J A; Brown E M
Calcium-dependent release of N-terminal fragments and intact immunoreactive parathyroid hormone by human pathological parathyroid tissue in vitro.
The Journal of clinical endocrinology and metabolism 1989;69(4):860-7.
1989: Conlin P R; Fajtova V T; Mortensen R M; LeBoff M S; Brown E M
Hysteresis in the relationship between serum ionized calcium and intact parathyroid hormone during recovery from induced hyper- and hypocalcemia in normal humans.
The Journal of clinical endocrinology and metabolism 1989;69(3):593-9.
1989: Seely E W; Moore T J; LeBoff M S; Brown E M
A single dose of lithium carbonate acutely elevates intact parathyroid hormone levels in humans.
Acta endocrinologica 1989;121(2):174-6.
1989: Ikeda K; Posillico J T; Boyle M B; Webb A C; Brown E M; Broadus A E
Microinjected Xenopus oocytes secrete mature, biologically active parathyroid hormone.
Molecular endocrinology (Baltimore, Md.) 1989;3(7):1084-9.
1989: Seely E W; LeBoff M S; Brown E M; Chen C; Posillico J T; Hollenberg N K; Williams G H
The calcium channel blocker diltiazem lowers serum parathyroid hormone levels in vivo and in vitro.
The Journal of clinical endocrinology and metabolism 1989;68(6):1007-12.
1989: Chen C J; Barnett J V; Congo D A; Brown E M
Divalent cations suppress 3',5'-adenosine monophosphate accumulation by stimulating a pertussis toxin-sensitive guanine nucleotide-binding protein in cultured bovine parathyroid cells.
Endocrinology 1989;124(1):233-9.
1989: Brown E M; Chen C J; LeBoff M S; Kifor O; Oetting M H; el-Hajj G
Mechanisms underlying the inverse control of parathyroid hormone secretion by calcium.
Society of General Physiologists series 1989;44():251-68.
1988: Ikeda K; Weir E C; Mangin M; Dannies P S; Kinder B; Deftos L J; Brown E M; Broadus A E
Expression of messenger ribonucleic acids encoding a parathyroid hormone-like peptide in normal human and animal tissues with abnormal expression in human parathyroid adenomas.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1230-6.
1988: Kifor O; Brown E M
Relationship between diacylglycerol levels and extracellular Ca2+ in dispersed bovine parathyroid cells.
Endocrinology 1988;123(6):2723-9.
1988: Brent G A; LeBoff M S; Seely E W; Conlin P R; Brown E M
Relationship between the concentration and rate of change of calcium and serum intact parathyroid hormone levels in normal humans.
The Journal of clinical endocrinology and metabolism 1988;67(5):944-50.
1988: Davis O K; Hawkins D S; Rubin L P; Posillico J T; Brown E M; Schiff I
Serum parathyroid hormone (PTH) in pregnant women determined by an immunoradiometric assay for intact PTH.
The Journal of clinical endocrinology and metabolism 1988;67(4):850-2.
1988: Chen C J; Anast C S; Brown E M
Effects of fluoride on parathyroid hormone secretion and intracellular second messengers in bovine parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1988;3(3):279-88.
1987: Oetting M; LeBoff M S; Levy S; Swiston L; Preston J; Chen C; Brown E M
Permeabilization reveals classical stimulus-secretion coupling in bovine parathyroid cells.
Endocrinology 1987;121(4):1571-6.
1987: Chen C J; Anast C S; Posillico J T; Brown E M
Effects of extracellular calcium and magnesium on cytosolic calcium concentration in Fura-2-loaded bovine parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1987;2(4):319-27.
1987: Posillico J T; Wilson R E; Srikanta S S; Eisenbarth G S; Letarte M; Quackenbush E J; Quaranta V; Kajaji S; Brown E M
Monoclonal antibody-mediated modulation of parathyroid hormone secretion by dispersed parathyroid cells.
Archives of surgery (Chicago, Ill. : 1960) 1987;122(4):436-42.
1987: Posillico J T; Srikanta S; Eisenbarth G; Quaranta V; Kajiji S; Brown E M
Binding of monoclonal antibody (4F2) to its cell surface antigen on dispersed adenomatous parathyroid cells raises cytosolic calcium and inhibits parathyroid hormone secretion.
The Journal of clinical endocrinology and metabolism 1987;64(1):43-50.
1987: Brown E M; LeBoff M S; Oetting M; Posillico J T; Chen C
Secretory control in normal and abnormal parathyroid tissue.
Recent progress in hormone research 1987;43():337-82.
1986: Posillico J T; Wortsman J; Srikanta S; Eisenbarth G S; Mallette L E; Brown E M
Parathyroid cell surface autoantibodies that inhibit parathyroid hormone secretion from dispersed human parathyroid cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(5):475-83.
1986: LeBoff M S; Chang J; Henry M; Beaudoin D; Swiston L; Brown E M
Role of cytosolic calcium in the control of cAMP content by calcium in bovine parathyroid cells.
Molecular and cellular endocrinology 1986;45(2-3):127-35.

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