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Wei-Zhong Zhu

Research Profile

Chemicals & Drugs

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Publications

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Khalid Chakir; Charlene Depry; Veronica L Dimaano; Nickolai Dulin; Theodore P Abraham; Jozef Bartunek; Shu-bai Liu; Eiki Takimoto; Gordon F Tomaselli; Marc Vanderheyden; Yang K Xiang; Rui-Ping Xiao; Jin Zhang; Manling Zhang; Wei-Zhong Zhu; David A Kass
Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart.
Dongmei Yang; Wei-Zhong Zhu; Bailong Xiao; Didier Brochet; S R Wayne Chen; Edward G Lakatta; Rui-Ping Xiao; Heping Cheng
Ca2+/calmodulin kinase II-dependent phosphorylation of ryanodine receptors suppresses Ca2+ sparks and Ca2+ waves in cardiac myocytes.
Yingbo Yang; Wei-Zhong Zhu; Mei-ling Joiner; Rong Zhang; Carmine V Oddis; Yue Hou; Jinying Yang; Edward E Price; Linda A Gleaves; Mesut Eren; Gemin Ni; Douglas E Vaughan; Rui-Ping Xiao; Mark E Anderson
Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo.

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All Publications

2011: Khalid Chakir; Charlene Depry; Veronica L Dimaano; Nickolai Dulin; Theodore P Abraham; Jozef Bartunek; Shu-bai Liu; Eiki Takimoto; Gordon F Tomaselli; Marc Vanderheyden; Yang K Xiang; Rui-Ping Xiao; Jin Zhang; Manling Zhang; Wei-Zhong Zhu; David A Kass
Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart.
Science translational medicine 2011;3(100):100ra88.
2007: Dongmei Yang; Wei-Zhong Zhu; Bailong Xiao; Didier Brochet; S R Wayne Chen; Edward G Lakatta; Rui-Ping Xiao; Heping Cheng
Ca2+/calmodulin kinase II-dependent phosphorylation of ryanodine receptors suppresses Ca2+ sparks and Ca2+ waves in cardiac myocytes.
Circulation research 2007;100(3):399-407.
2006: Yingbo Yang; Wei-Zhong Zhu; Mei-ling Joiner; Rong Zhang; Carmine V Oddis; Yue Hou; Jinying Yang; Edward E Price; Linda A Gleaves; Mesut Eren; Gemin Ni; Douglas E Vaughan; Rui-Ping Xiao; Mark E Anderson
Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo.
American journal of physiology. Heart and circulatory physiology 2006;291(6):H3065-75.
2005: Wei-Zhong Zhu; Khalid Chakir; Shengjun Zhang; Dongmei Yang; Catherine Lavoie; Michel Bouvier; Terence E Hébert; Edward G Lakatta; Heping Cheng; Rui-Ping Xiao
Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility.
Circulation research 2005;97(3):244-51.
2003: Dongmei Yang; Long-Sheng Song; Wei-Zhong Zhu; Khalid Chakir; Wei Wang; Caihong Wu; Yibin Wang; Rui-Ping Xiao; S R Wayne Chen; Heping Cheng
Calmodulin regulation of excitation-contraction coupling in cardiac myocytes.
Circulation research 2003;92(6):659-67.
2003: Wei-Zhong Zhu; Shi-Qiang Wang; Khalid Chakir; Dongmei Yang; Tong Zhang; Joan Heller Brown; Eric Devic; Brian K Kobilka; Heping Cheng; Rui-Ping Xiao
Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.
The Journal of clinical investigation 2003;111(5):617-25.
2002: Catherine Lavoie; Jean-François Mercier; Ali Salahpour; Dhiviya Umapathy; Andreas Breit; Louis Villeneuve; Wei-Zhong Zhu; Rui-Ping Xiao; Edward G Lakatta; Michel Bouvier; Terence E Hébert
Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy.
The Journal of biological chemistry 2002;277(38):35402-10.
2001: Wei-Zhong Zhu; Ming Zheng; Walter J Koch; RJ Lefkowitz; Brian K Kobilka; Rui-Ping Xiao
Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1607-12.
2000: Ming Zheng; Sheng-Jun Zhang; Wei-Zhong Zhu; Bruce D Ziman; Brian K Kobilka; Rui-Ping Xiao
beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes.
The Journal of biological chemistry 2000;275(51):40635-40.
2000: Ying-Ying Zhou; Dongmei Yang; Wei-Zhong Zhu; Sheng-Jun Zhang; D J Wang; Daniel K Rohrer; E Devic; Brian K Kobilka; Edward G Lakatta; Heping Cheng; Rui-Ping Xiao
Spontaneous activation of beta(2)- but not beta(1)-adrenoceptors expressed in cardiac myocytes from beta(1)beta(2) double knockout mice.
Molecular pharmacology 2000;58(5):887-94.
2000: Ying-Ying Zhou; Shi-Qiang Wang; Wei-Zhong Zhu; AJ Chruscinski; Brian K Kobilka; Bruce D Ziman; Su Wang; Edward G Lakatta; Heping Cheng; Rui-Ping Xiao
Culture and adenoviral infection of adult mouse cardiac myocytes: methods for cellular genetic physiology.
American journal of physiology. Heart and circulatory physiology 2000;279(1):H429-36.