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Gordon Brown

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Bernhard Kerscher; Janet A Willment; Gordon D Brown
The Dectin-2 family of C-type lectin-like receptors: an update.
Mohlopheni J Marakalala; Hector Mora-Montes; Carol A Munro; Graeme I Murray; Mihai G Netea; Joanna Potrykus; Kelly M Shepardson; Simon Vautier; Louise A Walker; Robert Wheeler; Robert A Cramer; Neil A R Gow; Alex Hopke; Ann Kerrigan; Donna M Maccallum; Alistair J P Brown; Gordon D Brown
Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1.
Anthony Plato; Janet A Willment; Gordon D Brown
C-type lectin-like receptors of the dectin-1 cluster: ligands and signaling pathways.

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All Publications

2013: Bernhard Kerscher; Janet A Willment; Gordon D Brown
The Dectin-2 family of C-type lectin-like receptors: an update.
International immunology 2013;25(5):271-7.
2013: Mohlopheni J Marakalala; Hector Mora-Montes; Carol A Munro; Graeme I Murray; Mihai G Netea; Joanna Potrykus; Kelly M Shepardson; Simon Vautier; Louise A Walker; Robert Wheeler; Robert A Cramer; Neil A R Gow; Alex Hopke; Ann Kerrigan; Donna M Maccallum; Alistair J P Brown; Gordon D Brown
Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1.
PLoS pathogens 2013;9(4):e1003315.
2013: Anthony Plato; Janet A Willment; Gordon D Brown
C-type lectin-like receptors of the dectin-1 cluster: ligands and signaling pathways.
International reviews of immunology 2013;32(2):134-56.
2012: Gordon D Brown; David W Denning; Neil A R Gow; Stuart M Levitz; Mihai G Netea; Theodore C White
Hidden killers: human fungal infections.
Science translational medicine 2012;4(165):165rv13.
2012: Simon Vautier; Rebecca A Drummond; Donna M MacCallum; Graeme I Murray; Pierre Redelinghuys; Gordon D Brown
Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract.
Infection and immunity 2012;80(12):4216-22.
2012: Sarah E Hardison; Gordon D Brown
C-type lectin receptors orchestrate antifungal immunity.
Nature immunology 2012;13(9):817-22.
2012: Lisa M Graham; Reto Guler; Vandana Gupta; William G Hornsell; Stella K Kim; Matti Kimberg; Angelina S Palma; Delyth M Reid; Georgia Schafer; Peter Sobieszczuk; Janet A Willment; Maria A Campanero-Rhodes; Kevin M Dennehy; Ten Feizi; Gordon D Brown
The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase.
The Journal of biological chemistry 2012;287(31):25964-74.
2012: Gordon D Brown; Mihai G Netea
Exciting developments in the immunology of fungal infections.
Cell host & microbe 2012;11(5):422-4.
2012: Gordon D Brown; David W Denning; Stuart M Levitz
Tackling human fungal infections.
Science (New York, N.Y.) 2012;336(6082):647.
2012: Simon Vautier; Donna M MacCallum; Gordon D Brown
C-type lectin receptors and cytokines in fungal immunity.
Cytokine 2012;58(1):89-99.
2012: A M Kerrigan; L Navarro-Nuñez; Elwira Pyz; S P Watson; Janet A Willment; B A Finney; Gordon D Brown
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2.
Journal of thrombosis and haemostasis : JTH 2012;10(3):484-6.
2012: Dominikus Strasser; Henning Urlaub; Gottfried Baier; Hanna Bergmann; Frank Brombacher; Gordon D Brown; Reto Guler; Karl-Peter Hopfner; Michael Leitges; Mohlopheni J Marakalala; Konstantin Neumann; Anna Rojowska; Jürgen Ruland
Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity.
Immunity 2012;36(1):32-42.
2012: Inês Faro-Trindade; Sabelo Hadebe; Ann M Kerrigan; Dirk M Lang; Pierre Redelinghuys; Delyth M Reid; Naren Srinivasan; Chad Steele; Helen Wainwright; Janet A Willment; Gordon D Brown
Characterisation of innate fungal recognition in the lung.
PloS one 2012;7(4):e35675.
2012: Ann M Kerrigan; Maria da Glória Teixeira de Sousa; Gordon D Brown
Simple assays for measuring innate interactions with fungi.
Methods in molecular biology (Clifton, N.J.) 2012;845():303-17.
2011: Rebecca A Drummond; Gordon D Brown
The role of Dectin-1 in the host defence against fungal infections.
Current opinion in microbiology 2011;14(4):392-9.
2011: Jacqueline U McDonald; Andrea Cortini; Marcela Rosas; Liliane Fossati-Jimack; Guang Sheng Ling; Kimberley J Lewis; Sharon Dewitt; Kate Liddiard; Gordon D Brown; Simon A Jones; Maurice B Hallett; Marina Botto; Philip R Taylor
In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(6):1972-82.
2011: Maria da Glória Sousa; Delyth M Reid; Edina Schweighoffer; Victor Tybulewicz; Jürgen Ruland; Jean Langhorne; Sho Yamasaki; Philip R Taylor; Sandro R Almeida; Gordon D Brown
Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin.
Cell host & microbe 2011;9(5):436-43.
2011: Hector Mora-Montes; Mihai G Netea; Gerben Ferwerda; Megan D Lenardon; Gordon D Brown; Anita R Mistry; Bart Jan Kullberg; Chris A O'Callaghan; Chirag C Sheth; Frank C Odds; Alistair J P Brown; Carol A Munro; Neil A R Gow
Recognition and blocking of innate immunity cells by Candida albicans chitin.
Infection and immunity 2011;79(5):1961-70.
2011: Ann M Kerrigan; Gordon D Brown
Syk-coupled C-type lectins in immunity.
Trends in immunology 2011;32(4):151-6.
2011: Rebecca A Drummond; Shinobu Saijo; Yoichiro Iwakura; Gordon D Brown
The role of Syk/CARD9 coupled C-type lectins in antifungal immunity.
European journal of immunology 2011;41(2):276-81.
2011: Mohlopheni J Marakalala; Reto Guler; Lungile Matika; Graeme Murray; Muazzam Jacobs; Frank Brombacher; Antonio Gigliotti Rothfuchs; Alan Sher; Gordon D Brown
The Syk/CARD9-coupled receptor Dectin-1 is not required for host resistance to Mycobacterium tuberculosis in mice.
Microbes and infection / Institut Pasteur 2011;13(2):198-201.
2011: Mohlopheni J Marakalala; Ann M Kerrigan; Gordon D Brown
Dectin-1: a role in antifungal defense and consequences of genetic polymorphisms in humans.
Mammalian genome : official journal of the International Mammalian Genome Society 2011;22(1-2):55-65.
2011: Elwira Pyż; Gordon D Brown
Screening for ligands of C-type lectin-like receptors.
Methods in molecular biology (Clifton, N.J.) 2011;748():1-19.
2011: Gordon D Brown
Innate antifungal immunity: the key role of phagocytes.
Annual review of immunology 2011;29():1-21.
2010: Simon Vautier; Maria da Glória Sousa; Gordon D Brown
C-type lectins, fungi and Th17 responses.
Cytokine & growth factor reviews 2010;21(6):405-12.
2010: Ann M Kerrigan; Gordon D Brown
Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs.
Immunological reviews 2010;234(1):335-52.
2010: Gordon D Brown
How fungi have shaped our understanding of mammalian immunology.
Cell host & microbe 2010;7(1):9-11.
2010: Mohlopheni Jackson Marakalala; Lisa M Graham; Gordon D Brown
The role of Syk/CARD9-coupled C-type lectin receptors in immunity to Mycobacterium tuberculosis infections.
Clinical & developmental immunology 2010;2010():567571.
2009: Lisa M Graham; Gordon D Brown
The Dectin-2 family of C-type lectins in immunity and homeostasis.
Cytokine 2009;48(1-2):148-55.
2009: S Vicky Tsoni; Ann M Kerrigan; Mohlopheni J Marakalala; Naren Srinivasan; Maureen Duffield; Philip R Taylor; Marina Botto; Chad Steele; Gordon D Brown
Complement C3 plays an essential role in the control of opportunistic fungal infections.
Infection and immunity 2009;77(9):3679-85.
2009: Matthew J Robinson; Fabiola Osorio; Marcela Rosas; Rui P Freitas; Edina Schweighoffer; Olaf Gross; Sjef Verbeek; Jürgen Ruland; Victor L J Tybulewicz; Gordon D Brown; Luis Ferreira Moita; Philip R Taylor; Caetano Reis e Sousa
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.
The Journal of experimental medicine 2009;206(9):2037-51.
2009: Ann M Kerrigan; Gordon D Brown
C-type lectins and phagocytosis.
Immunobiology 2009;214(7):562-75.
2009: Kevin M Dennehy; Janet A Willment; David L Williams; Gordon D Brown
Reciprocal regulation of IL-23 and IL-12 following co-activation of Dectin-1 and TLR signaling pathways.
European journal of immunology 2009;39(5):1379-86.
2009: Ann M Kerrigan; Kevin M Dennehy; Diego Mourão-Sá; Inês Faro-Trindade; Janet A Willment; Philip R Taylor; Johannes A Eble; Caetano Reis e Sousa; Gordon D Brown
CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4150-7.
2009: Delyth M Reid; Neil A R Gow; Gordon D Brown
Pattern recognition: recent insights from Dectin-1.
Current opinion in immunology 2009;21(1):30-7.
2009: Kerstin Werninghaus; Anna Babiak; Olaf Gross; Christoph Hölscher; Harald Dietrich; Else Marie Agger; Jörg Mages; Attila Mócsai; Hanne Schoenen; Katrin Finger; Falk Nimmerjahn; Gordon D Brown; Carsten J Kirschning; Antje Heit; Peter Andersen; Hermann Wagner; Jürgen Ruland; Roland Lang
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.
The Journal of experimental medicine 2009;206(1):89-97.
2009: Sigrid E M Heinsbroek; Lynn A Kamen; Philip R Taylor; Gordon D Brown; Joel A Swanson; Siamon Gordon
Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages.
Journal of innate immunity 2009;1(3):244-53.
2009: Georgia Schäfer; Muazzam Jacobs; Robert J Wilkinson; Gordon D Brown
Non-opsonic recognition of Mycobacterium tuberculosis by phagocytes.
Journal of innate immunity 2009;1(3):231-43.
2009: Georgia Schäfer; Reto Guler; Graeme Murray; Frank Brombacher; Gordon D Brown
The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model.
PloS one 2009;4(12):e8448.
2009: Georgia Schäfer; Gordon D Brown
Generation of retroviral macrophage cDNA expression libraries and functional screening for surface receptors.
Methods in molecular biology (Clifton, N.J.) 2009;531():1-15.
2008: Salomé LeibundGut-Landmann; Fabiola Osorio; Gordon D Brown; Caetano Reis e Sousa
Stimulation of dendritic cells via the dectin-1/Syk pathway allows priming of cytotoxic T-cell responses.
Blood 2008;112(13):4971-80.
2008: Sigrid E M Heinsbroek; Philip R Taylor; Fernando O Martinez; Luisa Martinez-Pomares; Gordon D Brown; Siamon Gordon
Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.
PLoS pathogens 2008;4(11):e1000218.
2008: Matti Kimberg; Gordon D Brown
Dectin-1 and its role in antifungal immunity.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2008;46(7):631-6.
2008: Gordon D Brown
Sensing necrosis with Mincle.
Nature immunology 2008;9(10):1099-100.
2008: Marcela Rosas; Kate Liddiard; Matti Kimberg; Inês Faro-Trindade; Jacqueline U McDonald; David L Williams; Gordon D Brown; Philip R Taylor
The induction of inflammation by dectin-1 in vivo is dependent on myeloid cell programming and the progression of phagocytosis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3549-57.
2008: Cristal Huysamen; Janet A Willment; Kevin M Dennehy; Gordon D Brown
CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes.
The Journal of biological chemistry 2008;283(24):16693-701.
2008: Elwira Pyz; Cristal Huysamen; Andrew S J Marshall; Siamon Gordon; Philip R Taylor; Gordon D Brown
Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand.
European journal of immunology 2008;38(4):1157-63.
2008: Kevin M Dennehy; Gerben Ferwerda; Inês Faro-Trindade; Elwira Pyz; Janet A Willment; Philip R Taylor; Ann Kerrigan; S Vicky Tsoni; Siamon Gordon; Friederike Meyer-Wentrup; Gosse J Adema; Bart Jan Kullberg; Edina Schweighoffer; Victor L J Tybulewicz; Hector Mora-Montes; Neil A R Gow; David L Williams; Mihai G Netea; Gordon D Brown
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.
European journal of immunology 2008;38(2):500-6.
2008: Janet A Willment; Gordon D Brown
C-type lectin receptors in antifungal immunity.
Trends in microbiology 2008;16(1):27-32.
2007: Neil A R Gow; Mihai G Netea; Carol A Munro; Gerben Ferwerda; Steven Bates; Hector Mora-Montes; Louise Walker; Trees Jansen; Liesbeth Jacobs; Vicky Tsoni; Gordon D Brown; Frank C Odds; Jos W M van der Meer; Alistair J P Brown; Bart Jan Kullberg
Immune recognition of Candida albicans beta-glucan by dectin-1.
The Journal of infectious diseases 2007;196(10):1565-71.
2007: Kevin M Dennehy; Gordon D Brown
The role of the beta-glucan receptor Dectin-1 in control of fungal infection.
Journal of leukocyte biology 2007;82(2):253-8.
2007: James Brown; Chris A O'Callaghan; Andrew S J Marshall; Robert J C Gilbert; Christian Siebold; Siamon Gordon; Gordon D Brown; E Yvonne Jones
Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.
Protein science : a publication of the Protein Society 2007;16(6):1042-52.
2007: Emma C Slack; Matthew J Robinson; Patricia Hernanz-Falcón; Gordon D Brown; David L Williams; Edina Schweighoffer; Victor L J Tybulewicz; Caetano Reis e Sousa
Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan.
European journal of immunology 2007;37(6):1600-12.
2007: Salomé LeibundGut-Landmann; Olaf Gross; Matthew J Robinson; Fabiola Osorio; Emma C Slack; S Vicky Tsoni; Edina Schweighoffer; Victor L J Tybulewicz; Gordon D Brown; Jürgen Ruland; Caetano Reis e Sousa
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.
Nature immunology 2007;8(6):630-8.
2007: Adam D Kennedy; Janet A Willment; David W Dorward; David L Williams; Gordon D Brown; Frank R DeLeo
Dectin-1 promotes fungicidal activity of human neutrophils.
European journal of immunology 2007;37(2):467-78.
2007: Philip R Taylor; S Vicky Tsoni; Janet A Willment; Kevin M Dennehy; Marcela Rosas; Helen Findon; Ken Haynes; Chad Steele; Marina Botto; Siamon Gordon; Gordon D Brown
Dectin-1 is required for beta-glucan recognition and control of fungal infection.
Nature immunology 2007;8(1):31-8.
2006: Andrew S J Marshall; Janet A Willment; Elwira Pyz; Kevin M Dennehy; Delyth M Reid; Pietro Dri; Siamon Gordon; Simon Y C Wong; Gordon D Brown
Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation.
European journal of immunology 2006;36(8):2159-69.
2006: Lisa M Graham; S Vicky Tsoni; Janet A Willment; David L Williams; Philip R Taylor; Siamon Gordon; Kevin M Dennehy; Gordon D Brown
Soluble Dectin-1 as a tool to detect beta-glucans.
Journal of immunological methods 2006;314(1-2):164-9.
2006: Sigrid E M Heinsbroek; Philip R Taylor; Marcela Rosas; Janet A Willment; David L Williams; Siamon Gordon; Gordon D Brown
Expression of functionally different dectin-1 isoforms by murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5513-8.
2006: Eamon P McGreal; Marcela Rosas; Gordon D Brown; Susanne Zamze; Simon Y C Wong; Siamon Gordon; Luisa Martinez-Pomares; Philip R Taylor
The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose.
Glycobiology 2006;16(5):422-30.
2006: Gordon D Brown
Macrophage receptors and innate immunity: insights from dectin-1.
Novartis Foundation symposium 2006;279():114-23; discussion 123-6, 216-9.
2006: Elwira Pyz; Andrew S J Marshall; Siamon Gordon; Gordon D Brown
C-type lectin-like receptors on myeloid cells.
Annals of medicine 2006;38(4):242-51.
2006: Gordon D Brown
Dectin-1: a signalling non-TLR pattern-recognition receptor.
Nature reviews. Immunology 2006;6(1):33-43.
2005: Yunpeng Su; Talitha Bakker; James Harris; Clarence Tsang; Gordon D Brown; Mark R Wormald; Siamon Gordon; Raymond A Dwek; Pauline M Rudd; Luisa Martinez-Pomares
Glycosylation influences the lectin activities of the macrophage mannose receptor.
The Journal of biological chemistry 2005;280(38):32811-20.
2005: Philip R Taylor; Delyth M Reid; Sigrid E M Heinsbroek; Gordon D Brown; Siamon Gordon; Simon Y C Wong
Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo.
European journal of immunology 2005;35(7):2163-74.
2005: Sigrid E M Heinsbroek; Gordon D Brown; Siamon Gordon
Dectin-1 escape by fungal dimorphism.
Trends in immunology 2005;26(7):352-4.
2005: Janet A Willment; Andrew S J Marshall; Delyth M Reid; David L Williams; Simon Y C Wong; Siamon Gordon; Gordon D Brown
The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells.
European journal of immunology 2005;35(5):1539-47.
2005: Neil C Rogers; Emma C Slack; Alexander D Edwards; Martijn A Nolte; Oliver Schulz; Edina Schweighoffer; David L Williams; Siamon Gordon; Victor L J Tybulewicz; Gordon D Brown; Caetano Reis e Sousa
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins.
Immunity 2005;22(4):507-17.
2005: Gordon D Brown; Siamon Gordon
Immune recognition of fungal beta-glucans.
Cellular microbiology 2005;7(4):471-9.
2005: P R Taylor; Luisa Martinez-Pomares; Martin Stacey; H-H Lin; Gordon D Brown; S Gordon
Macrophage receptors and immune recognition.
Annual review of immunology 2005;23():901-44.
2004: Jurgen Herre; Andrew S J Marshall; Emmanuelle Caron; Alexander D Edwards; David L Williams; Edina Schweighoffer; Victor L J Tybulewicz; Caetano Reis e Sousa; Siamon Gordon; Gordon D Brown
Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages.
Blood 2004;104(13):4038-45.
2004: Richard P Hobson; Carol A Munro; Steven Bates; Donna MacCallum; Jim E Cutler; Sigrid E M Heinsbroek; Gordon D Brown; Frank C Odds; Neil A R Gow
Loss of cell wall mannosylphosphate in Candida albicans does not influence macrophage recognition.
The Journal of biological chemistry 2004;279(38):39628-35.
2004: Subhankar Mukhopadhyay; Jurgen Herre; Gordon D Brown; Siamon Gordon
The potential for Toll-like receptors to collaborate with other innate immune receptors.
Immunology 2004;112(4):521-30.
2004: Andrew S J Marshall; Janet A Willment; Hsi-Hsien Lin; David L Williams; Siamon Gordon; Gordon D Brown
Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes.
The Journal of biological chemistry 2004;279(15):14792-802.
2004: Jurgen Herre; Siamon Gordon; Gordon D Brown
Dectin-1 and its role in the recognition of beta-glucans by macrophages.
Molecular immunology 2004;40(12):869-76.
2004: Philip R Taylor; Gordon D Brown; Jurgen Herre; David L Williams; Janet A Willment; Siamon Gordon
The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1157-62.
2004: Jurgen Herre; Janet A Willment; Siamon Gordon; Gordon D Brown
The role of Dectin-1 in antifungal immunity.
Critical reviews in immunology 2004;24(3):193-203.
2003: Janet A Willment; Hsi-Hsien Lin; Delyth M Reid; Philip R Taylor; David L Williams; Simon Y C Wong; Siamon Gordon; Gordon D Brown
Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4569-73.
2003: Gordon D Brown; Siamon Gordon
Fungal beta-glucans and mammalian immunity.
Immunity 2003;19(3):311-5.
2003: Philip R Taylor; Gordon D Brown; Anja B Geldhof; Luisa Martinez-Pomares; Siamon Gordon
Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo.
European journal of immunology 2003;33(8):2090-7.
2003: Gordon D Brown; Jurgen Herre; David L Williams; Janet A Willment; Andrew S J Marshall; Siamon Gordon
Dectin-1 mediates the biological effects of beta-glucans.
The Journal of experimental medicine 2003;197(9):1119-24.
2003: Luisa Martinez-Pomares; Delyth M Reid; Gordon D Brown; Philip R Taylor; Richard J Stillion; Sheena A Linehan; Susanne Zamze; Siamon Gordon; Simon Y C Wong
Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies.
Journal of leukocyte biology 2003;73(5):604-13.
2002: Joel A Dave; Nicolaas C Gey van Pittius; Albert D Beyers; Mario R W Ehlers; Gordon D Brown
Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages.
BMC microbiology 2002;2():30.
2002: Philip R Taylor; Gordon D Brown; Delyth M Reid; Janet A Willment; Luisa Martinez-Pomares; Siamon Gordon; Simon Y C Wong
The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3876-82.
2002: Gordon D Brown; Philip R Taylor; Delyth M Reid; Janet A Willment; David L Williams; Luisa Martinez-Pomares; Simon Y C Wong; Siamon Gordon
Dectin-1 is a major beta-glucan receptor on macrophages.
The Journal of experimental medicine 2002;196(3):407-12.
2001: Janet A Willment; Siamon Gordon; Gordon D Brown
Characterization of the human beta -glucan receptor and its alternatively spliced isoforms.
The Journal of biological chemistry 2001;276(47):43818-23.
2001: Gordon D Brown; Siamon Gordon
Immune recognition. A new receptor for beta-glucans.
Nature 2001;413(6851):36-7.
2001: Nicolaas C Gey van Pittius; Junaid Gamieldien; Winston Hide; Gordon D Brown; Roland Siezen; Albert D Beyers
The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria.
Genome biology 2001;2(10):RESEARCH0044.
2000: Gordon D Brown; J A Dave; Nicolaas C Gey van Pittius; L Stevens; Mario R W Ehlers; Albert D Beyers
The mycosins of Mycobacterium tuberculosis H37Rv: a family of subtilisin-like serine proteases.
Gene 2000;254(1-2):147-55.
1998: Paul R Meyers; William Bourn; Lafras M Steyn; Paul D van Helden; Albert D Beyers; Gordon D Brown
Novel method for rapid measurement of growth of mycobacteria in detergent-free media.
Journal of clinical microbiology 1998;36(9):2752-4.