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Zeng Zhu

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María Verónica Lopez; Angel A Rivera; Diego Viale; Minghui Wang; Zeng B Zhu; Ronald D Alvarez; Lorena Benedetti; Alicia I Bravo; Nicasio Cuneo; David T Curiel; Joanne T Douglas; Manuel Gidekel; Kristopher J Kimball; Osvaldo L Podhajcer
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice.
A A V Paupoo; Zeng B Zhu; Minghui Wang; Daniel T Rein; A Starzinski-Powitz; David T Curiel
A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effect.
Kristopher J Kimball; Angel A Rivera; Kurt R Zinn; Mert Icyuz; Vaibhav Saini; Jing Li; Zeng B Zhu; Gene P Siegal; Joanne T Douglas; David T Curiel; Ronald D Alvarez; Anton V Borovjagin
Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.

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2012: María Verónica Lopez; Angel A Rivera; Diego Viale; Minghui Wang; Zeng B Zhu; Ronald D Alvarez; Lorena Benedetti; Alicia I Bravo; Nicasio Cuneo; David T Curiel; Joanne T Douglas; Manuel Gidekel; Kristopher J Kimball; Osvaldo L Podhajcer
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(12):2222-33.
2010: A A V Paupoo; Zeng B Zhu; Minghui Wang; Daniel T Rein; A Starzinski-Powitz; David T Curiel
A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effect.
Human reproduction (Oxford, England) 2010;25(8):2068-83.
2009: Kristopher J Kimball; Angel A Rivera; Kurt R Zinn; Mert Icyuz; Vaibhav Saini; Jing Li; Zeng B Zhu; Gene P Siegal; Joanne T Douglas; David T Curiel; Ronald D Alvarez; Anton V Borovjagin
Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.
Molecular imaging 2009;8(5):264-77.
2009: Ilya V Ulasov; Mathew A Tyler; Zeng B Zhu; Yu Han; Tong-Chuan He; Lesniak Maciej
Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy.
International journal of oncology 2009;34(3):729-42.
2008: Essam-Eldin R Othman; Zeng B Zhu; David T Curiel; Nilufar Khatoon; Hosam T Salem; Essam Al-Din M Khalifa; Ayman Al-Hendy
Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells.
American journal of obstetrics and gynecology 2008;199(2):117.e1-6.
2008: Suvobroto Nandi; Ilya V Ulasov; Matthew A Tyler; Adam Quasar Sugihara; Luciana Molinero; Yu Han; Zeng B Zhu; Lesniak Maciej
Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells.
Cancer research 2008;68(14):5778-84.
2008: Zeng B Zhu; Baogen Lu; Miey Park; Sharmila K Makhija; Thomas M Numnum; James E Kendrick; Minghui Wang; Yuko Tsuruta; Paul Fisher; Ronald D Alvarez; Fen Zhou; Gene P Siegal; Hongju Wu; David T Curiel
Development of an optimized conditionally replicative adenoviral agent for ovarian cancer.
International journal of oncology 2008;32(6):1179-88.
2008: C P L Paul; Maaike Everts; Joel N Glasgow; Paul Dent; Paul B Fisher; Ilya V Ulasov; Maciej S. Lesniak; Mariam A Stoff-Khalili; Justin Roth; M A Preuss; C M F Dirven; M L M Lamfers; Gene P Siegal; Zeng B Zhu; David T Curiel
Characterization of infectivity of knob-modified adenoviral vectors in glioma.
Cancer biology & therapy 2008;7(5):786-93.
2008: Mariam A Stoff-Khalili; Angel A Rivera; Ana Nedeljkovic-Kurepa; Arrigo DeBenedetti; Xiao-Lin Li; Yoshinobu Odaka; Jagat Podduturi; Don Arthur Sibley; Gene P Siegal; Alexander Stoff; Scott Young; Zeng B Zhu; David T Curiel; J Michael Mathis
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control.
Breast cancer research and treatment 2008;108(1):43-55.
2008: T Michael Numnum; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel Rivera; Mariam A Stoff-Khalili; Ronald D Alvarez; Zeng B Zhu; David T Curiel
Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines.
Gynecologic oncology 2008;108(1):34-41.
2007: Zeng B Zhu; J Michael Mathis; Sharmila K Makhija; Baogen Lu; Minghui Wang; Shaonin Ji; Angel A Rivera; Eben Rosenthal; Gene P Siegal; David T Curiel
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck.
International journal of oncology 2007;31(5):1213-22.
2007: Mariam A Stoff-Khalili; Angel A Rivera; J Michael Mathis; nirupama banerjee; Amanda S Moon; A Hess; Rodney P Rocconi; T Michael Numnum; Maaike Everts; Louise T Chow; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; Hans Georg Bender; Peter Dall; Alexander Stoff; Larisa Pereboeva; David T Curiel
Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma.
Breast cancer research and treatment 2007;105(2):157-67.
2007: Ilya V Ulasov; Angel A Rivera; Yu Han; David T Curiel; Zeng B Zhu; Lesniak Maciej
Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells.
Journal of neurosurgery 2007;107(3):617-27.
2007: Ilya V Ulasov; Zeng B Zhu; Matthew A Tyler; Yu Han; Angel A Rivera; Andrey Khramtsov; David T Curiel; Lesniak Maciej
Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma.
Human gene therapy 2007;18(7):589-602.
2007: Ilya V Ulasov; Angel A Rivera; Adam M Sonabend; Lisa B Rivera; Ming Wang; Zeng B Zhu; Lesniak Maciej
Comparative evaluation of survivin, midkine and CXCR4 promoters for transcriptional targeting of glioma gene therapy.
Cancer biology & therapy 2007;6(5):679-85.
2007: Rodney P Rocconi; Zeng B Zhu; Mariam A Stoff-Khalili; Angel A Rivera; Baogen Lu; Minghui Wang; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd).
Gynecologic oncology 2007;105(1):113-21.
2007: Sophy Zheng; Ilya V Ulasov; Yu Han; Matthew A Tyler; Zeng B Zhu; Lesniak Maciej
Fiber-knob modifications enhance adenoviral tropism and gene transfer in malignant glioma.
The journal of gene medicine 2007;9(3):151-60.
2007: Y Tang; Tie Han; Maaike Everts; Zeng B Zhu; G Yancey Gillespie; David T Curiel; Hongju Wu
Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model.
Gene therapy 2007;14(6):523-32.
2007: Mariam A Stoff-Khalili; Angel A Rivera; Alexander Stoff; J Michael Mathis; Rodney P Rocconi; Qiana L Matthews; Michael T Numnum; Isabell Herrmann; Peter Dall; Devin E Eckhoff; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; David T Curiel
Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer.
International journal of cancer. Journal international du cancer 2007;120(4):935-41.
2007: Zeng B Zhu; Angel A Rivera; Sharmila K Makhija; Baogen Lu; Minghui Wang; Miiru Izumi; Robert James Cerfolio; Mariam A Stoff-Khalili; Fen Zhou; Koichi Takayama; Gene P Siegal; David T Curiel
Targeting lung cancer using an infectivity enhanced CXCR4-CRAd.
Lung cancer (Amsterdam, Netherlands) 2007;55(2):145-56.
2006: Rodney P Rocconi; Michael T Numnum; Zeng B Zhu; Baogen Lu; Minghui Wang; Angel A Rivera; Mariam A Stoff-Khalili; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy.
Gynecologic oncology 2006;103(3):985-9.
2006: Yabing Chen; Jianmin Xu; Nirag C Jhala; Pritish Pawar; Zeng B Zhu; Liping Ma; Chang-Hyun Byon; Jay M McDonald
Fas-mediated apoptosis in cholangiocarcinoma cells is enhanced by 3,3'-diindolylmethane through inhibition of AKT signaling and FLICE-like inhibitory protein.
The American journal of pathology 2006;169(5):1833-42.
2006: Zeng B Zhu; Yabing Chen; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Masato Yamamoto; shuyi wang; Gene P Siegal; David T Curiel; Jay M McDonald
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.
International journal of oncology 2006;29(5):1319-29.
2006: Natalya Belousova; Raymond Harris; Kurt R Zinn; Mary Ann Rhodes-Selser; Alexander Kotov; Olga Kotova; Minghui Wang; Rosemarie Aurigemma; Zeng B Zhu; David T Curiel; Ronald D Alvarez
Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette.
Molecular pharmacology 2006;70(5):1488-93.
2006: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; shuyi wang; Koichi Takayama; Gene P Siegal; Paul N Reynolds; David T Curiel
Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(7):701-11.
2006: J Michael Mathis; Phoebe L Stewart; Zeng B Zhu; David T Curiel
Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(9):2651-6.
2006: Winan J van Houdt; Yosef S Haviv; Baogen Lu; Minghui Wang; Angel A Rivera; Ilya V Ulasov; Martine L M Lamfers; Daniel T Rein; Lesniak Maciej; Gene P Siegal; Clemens M F Dirven; David T Curiel; Zeng B Zhu
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
Journal of neurosurgery 2006;104(4):583-92.
2006: David T Curiel; Zeng B Zhu
Combining chemotherapy with virotherapy: a novel treatment strategy for malignant pleural mesothelioma.
Cancer biology & therapy 2006;5(2):236-7.
2005: Michael J Passineau; Gene P Siegal; Maaike Everts; Alexander Pereboev; Darshana Jhala; Minghui Wang; Zeng B Zhu; Sangae Kim Park; David T Curiel; Gina M Nelson
The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma.
Leukemia & lymphoma 2005;46(11):1627-1638.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; J Michael Mathis; Maaike Everts; Minghui Wang; Yosuke Kawakami; Reinhard Waehler; Quiana L Mathews; Masato Yamamoto; Rodney P Rocconi; Gene P Siegal; Dirk F Richter; Peter Dall; Zeng B Zhu; David T Curiel
Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.
Cancer biology & therapy 2005;4(11):1203-10.
2005: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; SangAe Kim-Park; Ilya V Ulasov; Fen Zhou; Ronald D Alvarez; Gene P Siegal; David T Curiel
Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo.
International journal of oncology 2005;27(1):237-46.
2005: Baogen Lu; Sharmila K Makhija; Dirk M Nettelbeck; Angel A Rivera; Minghui Wang; Svetlana Komarova; Fen Zhou; Masato Yamamoto; Hidde J Haisma; Ronald D Alvarez; David T Curiel; Zeng B Zhu
Evaluation of tumor-specific promoter activities in melanoma.
Gene therapy 2005;12(4):330-8.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; nirupama banerjee; Maaike Everts; Scott Young; Gene P Siegal; Dirk F Richter; Minghui Wang; Peter Dall; J Michael Mathis; Zeng B Zhu; David T Curiel
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system.
Breast cancer research : BCR 2005;7(6):R1141-52.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Meredith Preuss; Fen Zhou; Gene P Siegal; Ronald D Alvarez; David T Curiel
Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.
Virology 2004;325(1):116-28.
2004: Yosef S Haviv; Winan J van Houdt; Baogen Lu; David T Curiel; Zeng B Zhu
Transcriptional targeting in renal cancer cell lines via the human CXCR4 promoter.
Molecular cancer therapeutics 2004;3(6):687-91.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Masato Yamamoto; M Yamaoto; Ronald D Alvarez; David T Curiel
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Gene therapy 2004;11(7):645-8.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Shannon Barker; Masato Yamaoto; Fengzhi Li; Ronald D Alvarez; David T Curiel
Transcriptional targeting of tumors with a novel tumor-specific survivin promoter.
Cancer gene therapy 2004;11(4):256-62.
2003: Zeng B Zhu; John E Volanakis
Determining alleles of the C2 gene by Southern Blotting.
Methods in molecular biology (Clifton, N.J.) 2003;210():259-68.
1998: Zeng B Zhu; T Prescott Atkinson; John E Volanakis
A novel type II complement C2 deficiency allele in an African-American family.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(2):578-84.
1998: Harry Schroeder; Zeng B Zhu; R E March; R Duncan Campbell; Seth Mark Berney; S A Nedospasov; Regina L Turetskaya; T Prescott Atkinson; Rodney C P Go; Max D Cooper; John E Volanakis
Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypes.
Molecular medicine (Cambridge, Mass.) 1998;4(2):72-86.
1998: Zeng B Zhu; K Totemchokchyakarn; T Prescott Atkinson; John E Volanakis
Molecular defects leading to human complement component C6 deficiency in an African-American family.
Clinical and experimental immunology 1998;111(1):91-6.
1998: Francesco Cucca; Zeng B Zhu; A Khanna; F Cossu; Mauro Congia; M Badiali; Rosanna Lampis; Fulvia Frau; Stefano De Virgiliis; A Cao; M Arnone; P Piras; R Duncan Campbell; Max D Cooper; John E Volanakis; S H Powis
Evaluation of IgA deficiency in Sardinians indicates a susceptibility gene is encoded within the HLA class III region.
Clinical and experimental immunology 1998;111(1):76-80.
1997: M L Johnson; L G Keeton; Zeng B Zhu; John E Volanakis; Max D Cooper; Harry Schroeder
Age-related changes in serum immunoglobulins in patients with familial IgA deficiency and common variable immunodeficiency (CVID).
Clinical and experimental immunology 1997;108(3):477-83.
1994: Zeng B Zhu; B Jian; John E Volanakis
Ancestry of SINE-R.C2 a human-specific retroposon.
Human genetics 1994;93(5):545-51.
1993: Y Ishii; Zeng B Zhu; K J Macon; John E Volanakis
Structure of the human C2 gene.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):170-4.
1992: Robert F Ashman; F M Schaffer; John D Kemp; W M Yokoyama; Zeng B Zhu; Max D Cooper; John E Volanakis
Genetic and immunologic analysis of a family containing five patients with common-variable immune deficiency or selective IgA deficiency.
Journal of clinical immunology 1992;12(6):406-14.
1992: John E Volanakis; Zeng B Zhu; F M Schaffer; K J Macon; J Palermos; B O Barger; R Go; R Duncan Campbell; Harry Schroeder; Max D Cooper
Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency.
The Journal of clinical investigation 1992;89(6):1914-22.
1992: Zeng B Zhu; Shie-Liang Hsieh; D R Bentley; R Duncan Campbell; John E Volanakis
A variable number of tandem repeats locus within the human complement C2 gene is associated with a retroposon derived from a human endogenous retrovirus.
The Journal of experimental medicine 1992;175(6):1783-7.
1990: Zeng B Zhu; John E Volanakis
Allelic associations of multiple RFLPs of the gene encoding complement protein C2.
American journal of human genetics 1990;46(5):956-62.
1989: F M Schaffer; J Palermos; Zeng B Zhu; B O Barger; Max D Cooper; John E Volanakis
Individuals with IgA deficiency and common variable immunodeficiency share polymorphisms of major histocompatibility complex class III genes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8015-9.