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Zdenek Zídek

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Co-Publications
Name
29
Holý, Antonín
20
Kmonícková, Eva
17
Franková, D
10
Masek, Karel
9
Farghali, Hassan
8
Potmesil, Petr
4
Otová, Berta
4
Anzenbacher, Pavel
4
Anzenbacherová, Eva
4
Buchar, Evzen
3
Canová, Nikolina
3
Boubelík, Michael
3
Masojídková, Milena
3
Nekvindová, Jana
3
Martínek, Jindrich

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Publications

TOP 3
Farghali Hassan; Cerný Dalibor; Kameníková Ludmila; Martínek Jindrich; Horínek Ales; Kmonícková Eva; Zídek Zdenek
Resveratrol attenuates lipopolysaccharide-induced hepatitis in D-galactosamine sensitized rats: role of nitric oxide synthase 2 and heme oxygenase-1.
Zídek Z; Anzenbacher P; Kmonícková E
Current status and challenges of cytokine pharmacology.
Cerný Dalibor; Canová Nikolina Kutinová; Martínek Jindrich; Horínek Ales; Kmonícková Eva; Zídek Zdenek; Farghali Hassan
Effects of resveratrol pretreatment on tert-butylhydroperoxide induced hepatocyte toxicity in immobilized perifused hepatocytes: involvement of inducible nitric oxide synthase and hemoxygenase-1.

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All Publications

2009: Farghali Hassan; Cerný Dalibor; Kameníková Ludmila; Martínek Jindrich; Horínek Ales; Kmonícková Eva; Zídek Zdenek
Resveratrol attenuates lipopolysaccharide-induced hepatitis in D-galactosamine sensitized rats: role of nitric oxide synthase 2 and heme oxygenase-1.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2009;21(3-4):216-25.
2009: Zídek Z; Anzenbacher P; Kmonícková E
Current status and challenges of cytokine pharmacology.
British journal of pharmacology 2009;157(3):342-61.
2009: Cerný Dalibor; Canová Nikolina Kutinová; Martínek Jindrich; Horínek Ales; Kmonícková Eva; Zídek Zdenek; Farghali Hassan
Effects of resveratrol pretreatment on tert-butylhydroperoxide induced hepatocyte toxicity in immobilized perifused hepatocytes: involvement of inducible nitric oxide synthase and hemoxygenase-1.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2009;20(1):1-8.
2008: Kmonícková Eva; Melkusová Petra; Harmatha Juraj; Vokác Karel; Farghali Hassan; Zídek Zdenek
Inhibitor of sarco-endoplasmic reticulum Ca2+-ATPase thapsigargin stimulates production of nitric oxide and secretion of interferon-gamma.
European journal of pharmacology 2008;588(1):85-92.
2008: Harmatha Juraj; Vokác Karel; Kmonícková Eva; Zídek Zdenek
Lack of interference of common phytoecdysteroids with production of nitric oxide by immune-activated mammalian macrophages.
Steroids 2008;73(4):466-71.
2008: Cesnek Michal; Holý Antonín; Masojídková Milena; Kmonícková Eva; Zídek Zdenek
Synthesis of guanidino analogues of PMPDAP and their immunobiological activity.
Bioorganic & medicinal chemistry 2008;16(2):965-80.
2008: Anzenbacherová E; Anzenbacher P; Zídek Z; Buchar E; Kmonícková E; Potmesil P; Nekvindová J; Veinlichová A; Holý A
In vivo study of the effect of antiviral acyclic nucleotide phosphonate (R)-9-[2-(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its prodrug tenofovir disoproxil fumarate on rat microsomal cytochrome P450.
Physiological research / Academia Scientiarum Bohemoslovaca 2008;57(5):761-7.
2008: Farghali H; Hodis J; Kutinová-Canová N; Potmesil P; Kmonícková E; Zídek Z
Glucose release as a response to glucagon in rat hepatocyte culture: involvement of NO signaling.
Physiological research / Academia Scientiarum Bohemoslovaca 2008;57(4):569-75.
2007: Kmonícková Eva; Melkusová Petra; Farghali Hassan; Holý Antonín; Zídek Zdenek
Nitric oxide production in mouse and rat macrophages: a rapid and efficient assay for screening of drugs immunostimulatory effects in human cells.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2007;17(3-4):160-9.
2007: Zídek Zdenek; Kmonícková Eva; Holý Antonín
Secretion of antiretroviral chemokines by human cells cultured with acyclic nucleoside phosphonates.
European journal of pharmacology 2007;574(1):77-84.
2007: Canová N Kutinová; Kmonícková E; Martínek J; Zídek Z; Farghali H
Thapsigargin, a selective inhibitor of sarco-endoplasmic reticulum Ca2+ -ATPases, modulates nitric oxide production and cell death of primary rat hepatocytes in culture.
Cell biology and toxicology 2007;23(5):337-54.
2007: Potmesil Petr; Holý Antonín; Kmonícková Eva; Krízková Jana; Zídek Zdenek
Acyclic nucleoside phosphonate antivirals activate gene expression of monocyte chemotactic protein 1 and 3.
Journal of biomedical science 2007;14(1):59-66.
2007: Hodis J; Kutinová-Canová N; Potmesil P; Kameníková L; Kmonícková E; Zídek Z; Farghali H
The role of adrenergic agonists on glycogenolysis in rat hepatocyte cultures and possible involvement of NO.
Physiological research / Academia Scientiarum Bohemoslovaca 2007;56(4):419-25.
2006: Nekvindová J; Masek V; Veinlichová A; Anzenbacherová E; Anzenbacher P; Zídek Z; Holý A
Inhibition of human liver microsomal cytochrome P450 activities by adefovir and tenofovir.
Xenobiotica; the fate of foreign compounds in biological systems 2006;36(12):1165-77.
2006: Matal Jaroslav; Orság Jirí; Nekvindová Jana; Anzenbacherová Eva; Veinlichová Alena; Anzenbacher Pavel; Zídek Zdenek; Holý Antonín
Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing monooxygenase 3.
Neuro endocrinology letters 2006;27 Suppl 2():27-30.
2006: Potmesil Petr; Krecmerová Marcela; Kmonícková Eva; Holý Antonín; Zídek Zdenek
Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives.
European journal of pharmacology 2006;540(1-3):191-9.
2006: Zídek Zdenek; Anzenbacher Pavel; Anzenbacherová Eva; Buchar Evzen; Kmonícková Eva; Potmesil Petr; Holý Antonín
In vivo effects of antiviral acyclic nucleoside phosphonate 9-[2-(phosphonomethoxy)ethyl]adenine (adefovir) on cytochrome P450 system of rat liver microsomes.
Journal of biomedical science 2006;13(3):295-301.
2006: Kmonícková Eva; Potmesil Petr; Holý Antonín; Zídek Zdenek
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
European journal of pharmacology 2006;530(1-2):179-87.
2005: Kmonícková Eva; Canová Nikolina Kutinová; Farghali Hassan; Holý Antonín; Zídek Zdenek
Modulator of intracellular Ca(2+), thapsigargin, interferes with in vitro secretion of cytokines and nitric oxide.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005;149(2):321-4.
2005: Zídek Zdenek; Kmonícková Eva; Holý Antonín
Cytotoxicity of pivoxil esters of antiviral acyclic nucleoside phosphonates: adefovir dipivoxil versus adefovir.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005;149(2):315-9.
2005: Cesnek Michal; Holý Antonín; Masojídková Milena; Zídek Zdenek
Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages.
Bioorganic & medicinal chemistry 2005;13(8):2917-26.
2005: Doláková Petra; Holý Antonín; Zídek Zdenek; Masojídková Milena; Kmonícková Eva
Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivatives.
Bioorganic & medicinal chemistry 2005;13(7):2349-54.
2004: Zídek Zdenek; Kmonícková Eva; Holý Antonín
Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues.
European journal of pharmacology 2004;501(1-3):79-86.
2004: Rasková H; Zídek Z
Surprises and omissions in toxicology.
Central European journal of public health 2004;12 Suppl():S94-6.
2004: Kmonícková E; Zídek Z
Quantitative aspects of lipopolysaccharide and cytokine requirements to generate nitric oxide in macrophages from LPS-hyporesponsive (Lps(d)) C3H/HeJ mice.
Folia microbiologica 2004;49(6):737-44.
2003: Botros Sanaa; William Samia; Hammam Olfat; Zídek Zdenek; Holý Antonín
Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice.
Antimicrobial agents and chemotherapy 2003;47(12):3853-8.
2003: Zídek Zdenek; Potmesil Petr; Holý Antonín
Cytostatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes.
Toxicology and applied pharmacology 2003;192(3):246-53.
2003: Zídek Zdenek; Potmesil Petr; Kmoníèková Eva; Holý Antonín
Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N6-substituted adenines, and 2,6-diaminopurines.
European journal of pharmacology 2003;475(1-3):149-59.
2002: Tucková Ludmila; Novotná Jana; Novák Petr; Flegelová Zuzana; Kveton Tomás; Jelínková Lenka; Zídek Zdenek; Man Petr; Tlaskalová-Hogenová Helena
Activation of macrophages by gliadin fragments: isolation and characterization of active peptide.
Journal of leukocyte biology 2002;71(4):625-31.
2001: Zídek Z; Franková D; Holý A
Activation by 9-(R)-[2-(phosphonomethoxy)propyl]adenine of chemokine (RANTES, macrophage inflammatory protein 1alpha) and cytokine (tumor necrosis factor alpha, interleukin-10 [IL-10], IL-1beta) production.
Antimicrobial agents and chemotherapy 2001;45(12):3381-6.
2001: Trebichavský I; Zídek Z; Franková D; Zahradnícková M; Splíchal I
Nitric oxide metabolites in gnotobiotic piglets orally infected with Salmonella enterica serovar typhimurium.
Folia microbiologica 2001;46(4):353-8.
2000: Zídek Z; Franková D; Holý A
Macrophage activation by antiviral acyclic nucleoside phosphonates in dependence on priming immune stimuli.
International journal of immunopharmacology 2000;22(12):1121-9.
2000: Zídek Z; Franková D; Boubelík M
Genetic variation in in-vitro cytokine-induced production of nitric oxide by murine peritoneal macrophages.
Pharmacogenetics 2000;10(6):493-501.
2000: Tucková L; Flegelová Z; Tlaskalová-Hogenová H; Zídek Z
Activation of macrophages by food antigens: enhancing effect of gluten on nitric oxide and cytokine production.
Journal of leukocyte biology 2000;67(3):312-8.
2000: Masek K; Petrovický P; Sevcík J; Zídek Z; Franková D
Past, present and future of psychoneuroimmunology.
Toxicology 2000;142(3):179-88.
1999: Zídek Z; Franková D; Holý A
Chemokines, nitric oxide and antiarthritic effects of 9-(2-phosphonomethoxyethyl)adenine (Adefovir).
European journal of pharmacology 1999;376(1-2):91-100.
1999: Zídek Z; Franková D; Holý A
Stimulation of cytokine and nitric oxide production by acyclic nucleoside phosphonates.
Nucleosides & nucleotides 1999;18(4-5):959-61.
1999: Franková D; Zídek Z; Buchar E; Jiøièka Z; Holý A
Antiinflammatory effects of phosphonomethoxyethyl analogues of adenine in a model of adjuvant arthritis.
Nucleosides & nucleotides 1999;18(4-5):955-8.
1997: Zídek Z; Franková D; Holý A; Boubelík M; Dráber P
Inhibition of murine macrophage nitric oxide synthase expression by a pivoxil prodrug of antiviral acyclic nucleotide analogue 9-(2-phosphonomethoxyethyl)adenine.
Biochemical pharmacology 1997;54(8):855-61.
1997: Zídek Z; Holý A; Franková D
Immunomodulatory properties of antiviral acyclic nucleotide analogues: cytokine stimulatory and nitric oxide costimulatory effects.
International journal of immunopharmacology 1997;19(9-10):587-97.
1997: Zídek Z; Holý A; Franková D
Antiretroviral agent (R)-9-(2-phosphonomethoxypropyl)adenine stimulates cytokine and nitric oxide production.
European journal of pharmacology 1997;331(2-3):245-52.
1997: Otová B; Zídek Z; Holý A; Votruba I; Sladká M; Marinov I; Lesková V
Antitumor activity of novel purine acyclic nucleotide analogs PMEA and PMEDAP.
In vivo (Athens, Greece) 1997;11(2):163-7.
1997: Farghali H; Zídek Z; Hynie S
Effects of nitroprusside as a nitric oxide donor on anoxia/reoxygenation and D-galactosamine hepatic injuries: a study in perfused hepatocytes.
Physiological research / Academia Scientiarum Bohemoslovaca 1997;46(5):363-9.
1996: Zídek Z; Lotzová E; Franková D; Savary C A
Indirect stimulatory effects of murine interleukin-12 on in vitro production of nitric oxide by mouse peritoneal cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(5):389-93.
1995: Zídek Z; Franková D; Otová B
Lack of causal relationship between inducibility/severity of adjuvant arthritis in the rat and disease associated changes in production of nitric oxide by macrophages.
Annals of the rheumatic diseases 1995;54(4):325-7.
1995: Zídek Z; Franková D
Interferon-gamma/tumour necrosis factor-alpha synergism as a mechanism for enhanced nitric oxide production following in vivo administration of muramyl dipeptide (MDP) to mice.
International journal of immunopharmacology 1995;17(4):313-7.
1995: Mráz M; Donát P; Starec M; Zídek Z; Rasková H; Hynie S
[Differences in the behavior of organic lesions, immunologic and metabolic parameters in 2 inbred strains of rats]
Ceskoslovenská fysiologie / Ústrední ústav biologický 1995;44(1):18-20.
1994: Starec M; Mráz M; Zídek Z; Donát P; Krsiak M; Hynie S; Rasková H
Genetic differences in immunomodulation, behavior, and stress-induced organ lesions.
Annals of the New York Academy of Sciences 1994;741():252-62.
1994: Zídek Z
Immune-related edemagenic activity of glutamines and glutamic acid, components of immunomodulatory agents.
Agents and actions 1994;42(3-4):163-6.
1994: Otová B; Zídek Z; Holý A; Votruba I; Franková D
Immunomodulatory properties of 9-(2-phosphonomethoxyethyl)-adenine (PMEA).
Folia biologica 1994;40(4):185-92.
1993: Zídek Z; Masek K; Franková D; Flegel M
T-cell-dependent immunobiological activity of a desmuramyl analog of muramyl dipeptide, adamantylamide dipeptide (AdDP), and D-isoglutamine.
International journal of immunopharmacology 1993;15(5):631-7.
1993: Zídek Z; Franková D; Masek K
Some cellular and pathophysiological correlates of the inflammatory effects of a synthetic immunomodulatory agent, muramyl dipeptide (MDP).
Agents and actions 1993;38(1-2):106-15.
1993: Otová B; Krenová D; Zídek Z; Holý A; Votruba I; Kren V
Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). III. Rat and mouse carcinomas and sarcomas.
Folia biologica 1993;39(6):311-4.
1992: Zídek Z
Differences in proinflammatory activity of several immunomodulatory derivatives of muramyl dipeptide (MDP) with special reference to the mechanism of the MDP effects.
Agents and actions 1992;36(1-2):136-45.
1986: Kadlec O; Masek K; Zídek Z
The influence of immune status on the in vitro sensitivity of serotoninergic receptors in the rat stomach strip.
Methods and findings in experimental and clinical pharmacology 1986;8(2):127-9.
1986: Kameníková L; Zídek Z; Buchar E; Kren V; Krenová D; Janku I
Study of relationship between allogeneic transplantability of tumors and their effects on drug-metabolizing system in rats.
Neoplasma 1986;33(1):21-5.
1985: Zídek Z; Masek K
Edemagenic activity of aqueous form of muramyl dipeptide (MDP) in rats.
Methods and findings in experimental and clinical pharmacology 1985;7(8):419-26.
1984: Yanev S; Zídek Z; Kadiiska M; Serbinova E; Masek K; Stoytchev T
Hepatic mixed-function oxidase system and microsomal lipid peroxidation in rats treated with a synthetic immunomodulator, N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP).
Methods and findings in experimental and clinical pharmacology 1984;6(6):311-5.
1984: Zídek Z; Masek K; Sedivý F
Anti-inflammatory effects of muramyl dipeptide in experimental models of acute inflammation.
Agents and actions 1984;14(1):72-5.
1983: Zídek Z; Capková J; Boubelík M; Masek K
Opposite effects of the synthetic immunomodulator, muramyl dipeptide, on rejection of mouse skin allografts.
European journal of immunology 1983;13(10):859-61.
1983: Zídek Z; Kameníková L; Buchar E; Janku I; Masek K
Biotransformation of drugs in rats treated with a synthetic muramyl dipeptide, N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP).
International journal of immunopharmacology 1983;5(2):151-5.
1982: Zídek Z; Masek K; Jiricka Z
Arthritogenic activity of a synthetic immunoadjuvant, muramyl dipeptide.
Infection and immunity 1982;35(2):674-9.
1981: Zídek Z; Janku I
Increased acetylation and elimination of sulphadimidine in rats with adjuvant induced arthritis.
European journal of drug metabolism and pharmacokinetics 1981;6(4):255-9.

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