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Juleen Zierath

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Skeletal Muscle

Chemicals & Drugs

Physiology

Disorders

Phenomena

Phosphorylation

Living Beings

Mice
Rats

Activities & Behaviors

Exercise

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Co-Publications
Name
62
Wallberg-Henriksson, Harriet
36
Krook, Anna
29
Chibalin, Alexander
28
Galuska, Dana
19
Ryder, Jeffrey
15
Long, Yun Chau
14
Björnholm, Marie
11
Karlsson, Håkan
9
Koistinen, Heikki
8
Barnes, Brian
8
Bouzakri, Karim
8
Glund, Stephan
7
Charron, Maureen
7
Kawano, Y
7
Rincon, J

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Publications

TOP 3
Peck Grantley R; Chavez Jose A; Roach William G; Budnik Bogdan A; Lane William S; Karlsson Håkan K R; Zierath Juleen R; Lienhard Gustav E
Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation.
Rune A; Osler M E; Fritz T; Zierath J R
Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.
Barrès Romain; Osler Megan E; Yan Jie; Rune Anna; Fritz Tomas; Caidahl Kenneth; Krook Anna; Zierath Juleen R
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.

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All Publications

2009: Peck Grantley R; Chavez Jose A; Roach William G; Budnik Bogdan A; Lane William S; Karlsson Håkan K R; Zierath Juleen R; Lienhard Gustav E
Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation.
The Journal of biological chemistry 2009;284(44):30016-23.
2009: Rune A; Osler M E; Fritz T; Zierath J R
Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.
Diabetologia 2009;52(10):2182-9.
2009: Barrès Romain; Osler Megan E; Yan Jie; Rune Anna; Fritz Tomas; Caidahl Kenneth; Krook Anna; Zierath Juleen R
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.
Cell metabolism 2009;10(3):189-98.
2009: Krook A; Zierath J R
Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA.
Diabetologia 2009;52(7):1231-9.
2009: Egan Brendan; Zierath Juleen R
Hunting for the SNARK in metabolic disease.
American journal of physiology. Endocrinology and metabolism 2009;296(5):E969-72.
2009: Treebak J T; Frøsig C; Pehmøller C; Chen S; Maarbjerg S J; Brandt N; MacKintosh C; Zierath J R; Hardie D G; Kiens B; Richter E A; Pilegaard H; Wojtaszewski J F P
Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle.
Diabetologia 2009;52(5):891-900.
2009: Wallberg-Henriksson Harriet; Zierath Juleen R
A new twist on brown fat metabolism.
Cell 2009;137(1):22-4.
2009: Sultan Ariane; Strodthoff Daniela; Robertson Anna-Karin; Paulsson-Berne Gabrielle; Fauconnier Jeremy; Parini Paolo; Rydén Mikael; Thierry-Mieg Nicolas; Johansson Maria E; Chibalin Alexander V; Zierath Juleen R; Arner Peter; Hansson Göran K
T cell-mediated inflammation in adipose tissue does not cause insulin resistance in hyperlipidemic mice.
Circulation research 2009;104(8):961-8.
2009: Karlsson Håkan K R; Chibalin Alexander V; Koistinen Heikki A; Yang Jing; Koumanov Francoise; Wallberg-Henriksson Harriet; Zierath Juleen R; Holman Geoffrey D
Kinetics of GLUT4 trafficking in rat and human skeletal muscle.
Diabetes 2009;58(4):847-54.
2009: Glund Stephan; Treebak Jonas T; Long Yun Chau; Barres Romain; Viollet Benoit; Wojtaszewski Jorgen F; Zierath Juleen R
Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle.
Endocrinology 2009;150(2):600-6.
2008: Benziane Boubacar; Burton Timothy J; Scanlan Brendan; Galuska Dana; Canny Benedict J; Chibalin Alexander V; Zierath Juleen R; Stepto Nigel K
Divergent cell signaling after short-term intensified endurance training in human skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2008;295(6):E1427-38.
2008: Chadt Alexandra; Leicht Katja; Deshmukh Atul; Jiang Lake Q; Scherneck Stephan; Bernhardt Ulrike; Dreja Tanja; Vogel Heike; Schmolz Katja; Kluge Reinhart; Zierath Juleen R; Hultschig Claus; Hoeben Rob C; Schürmann Annette; Joost Hans-Georg; Al-Hasani Hadi
Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity.
Nature genetics 2008;40(11):1354-9.
2008: Lundholm L; Bryzgalova G; Gao H; Portwood N; Fält S; Berndt K D; Dicker A; Galuska D; Zierath J R; Gustafsson J-A; Efendic S; Dahlman-Wright K; Khan A
The estrogen receptor {alpha}-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms.
The Journal of endocrinology 2008;199(2):275-86.
2008: Vieira Elaine; Nilsson Elisabeth C; Nerstedt Annika; Ormestad Mattias; Long Yun Chau; Garcia-Roves Pablo M; Zierath Juleen R; Mahlapuu Margit
Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2008;295(5):E1032-7.
2008: Kuoppamaa Heidi; Skrobuk Paulina; Sihvo Maarit; Hiukka Anne; Chibalin Alexander V; Zierath Juleen R; Koistinen Heikki A
Globular adiponectin stimulates glucose transport in type 2 diabetic muscle.
Diabetes/metabolism research and reviews 2008;24(7):554-62.
2008: Deshmukh A S; Hawley J A; Zierath J R
Exercise-induced phospho-proteins in skeletal muscle.
International journal of obesity (2005) 2008;32 Suppl 4():S18-23.
2008: Long Yun Chau; Zierath Juleen R
Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2008;295(3):E545-52.
2008: Austin Reginald L; Rune Anna; Bouzakri Karim; Zierath Juleen R; Krook Anna
siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.
Diabetes 2008;57(8):2066-73.
2008: Cabrera Over; Jacques-Silva M Caroline; Speier Stephan; Yang Shao-Nian; Köhler Martin; Fachado Alberto; Vieira Elaine; Zierath Juleen R; Kibbey Richard; Berman Dora M; Kenyon Norma S; Ricordi Camillo; Caicedo Alejandro; Berggren Per-Olof
Glutamate is a positive autocrine signal for glucagon release.
Cell metabolism 2008;7(6):545-54.
2008: Bouzakri Karim; Austin Reginald; Rune Anna; Lassman Michael E; Garcia-Roves Pablo M; Berger Joel P; Krook Anna; Chibalin Alexander V; Zhang Bei B; Zierath Juleen R
Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle.
Diabetes 2008;57(6):1508-16.
2008: Deshmukh Atul S; Treebak Jonas T; Long Yun Chau; Viollet Benoit; Wojtaszewski Jørgen F P; Zierath Juleen R
Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling.
Molecular endocrinology (Baltimore, Md.) 2008;22(5):1105-12.
2008: Osler Megan E; Zierath Juleen R
Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle.
Endocrinology 2008;149(3):935-41.
2008: Chibalin Alexander V; Leng Ying; Vieira Elaine; Krook Anna; Björnholm Marie; Long Yun Chau; Kotova Olga; Zhong Zhihui; Sakane Fumio; Steiler Tatiana; Nylén Carolina; Wang Jianjun; Laakso Markku; Topham Matthew K; Gilbert Marc; Wallberg-Henriksson Harriet; Zierath Juleen R
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.
Cell 2008;132(3):375-86.
2008: Zierath Juleen R
Xth International Symposium on insulin receptors and insulin action.
Acta physiologica (Oxford, England) 2008;192(1):1.
2007: Osler M E; Zierath J R
Fighting the battle of the bulge: exercise training in early-onset type 2 diabetes.
Diabetologia 2007;50(7):1362-4.
2007: Glund Stephan; Deshmukh Atul; Long Yun Chau; Moller Theodore; Koistinen Heikki A; Caidahl Kenneth; Zierath Juleen R; Krook Anna
Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.
Diabetes 2007;56(6):1630-7.
2007: Parikh Hemang; Carlsson Emma; Chutkow William A; Johansson Lovisa E; Storgaard Heidi; Poulsen Pernille; Saxena Richa; Ladd Christine; Schulze P Christian; Mazzini Michael J; Jensen Christine Bjørn; Krook Anna; Björnholm Marie; Tornqvist Hans; Zierath Juleen R; Ridderstråle Martin; Altshuler David; Lee Richard T; Vaag Allan; Groop Leif C; Mootha Vamsi K
TXNIP regulates peripheral glucose metabolism in humans.
PLoS medicine 2007;4(5):e158.
2007: Zierath Juleen R
The path to insulin resistance: paved with ceramides?
Cell metabolism 2007;5(3):161-3.
2007: Bouzakri Karim; Zierath Juleen R
MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.
The Journal of biological chemistry 2007;282(11):7783-9.
2007: Long Yun Chau; Glund Stephan; Garcia-Roves Pablo M; Zierath Juleen R
Calcineurin regulates skeletal muscle metabolism via coordinated changes in gene expression.
The Journal of biological chemistry 2007;282(3):1607-14.
2007: Karlsson Håkan K R; Zierath Juleen R
Insulin signaling and glucose transport in insulin resistant human skeletal muscle.
Cell biochemistry and biophysics 2007;48(2-3):103-13.
2006: O'Gorman D J; Karlsson H K R; McQuaid S; Yousif O; Rahman Y; Gasparro D; Glund S; Chibalin A V; Zierath J R; Nolan J J
Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes.
Diabetologia 2006;49(12):2983-92.
2006: Fritz Tomas; Krämer David K; Karlsson Håkan K R; Galuska Dana; Engfeldt Peter; Zierath Juleen R; Krook Anna
Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients.
Diabetes/metabolism research and reviews 2006;22(6):492-8.
2006: Wang J; Shafqat J; Hall K; Ståhlberg M; Wivall-Helleryd I-L; Bouzakri K; Zierath J R; Brismar K; Jörnvall H; Lewitt M S
Specific cleavage of insulin-like growth factor-binding protein-1 by a novel protease activity.
Cellular and molecular life sciences : CMLS 2006;63(19-20):2405-14.
2006: Cantó Carles; Chibalin Alexander V; Barnes Brian R; Glund Stephan; Suárez Elisabet; Ryder Jeffrey W; Palacín Manuel; Zierath Juleen R; Zorzano Antonio; Gumà Anna
Neuregulins mediate calcium-induced glucose transport during muscle contraction.
The Journal of biological chemistry 2006;281(31):21690-7.
2006: Long Yun Chau; Zierath Juleen R
AMP-activated protein kinase signaling in metabolic regulation.
The Journal of clinical investigation 2006;116(7):1776-83.
2006: Bouzakri Karim; Zachrisson Anna; Al-Khalili Lubna; Zhang Bei B; Koistinen Heikki A; Krook Anna; Zierath Juleen R
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle.
Cell metabolism 2006;4(1):89-96.
2006: Treebak Jonas T; Glund Stephan; Deshmukh Atul; Klein Ditte K; Long Yun Chau; Jensen Thomas E; Jørgensen Sebastian B; Viollet Benoit; Andersson Leif; Neumann Dietbert; Wallimann Theo; Richter Erik A; Chibalin Alexander V; Zierath Juleen R; Wojtaszewski Jørgen F P
AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.
Diabetes 2006;55(7):2051-8.
2006: Deshmukh Atul; Coffey Vernon G; Zhong Zhihui; Chibalin Alexander V; Hawley John A; Zierath Juleen R
Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle.
Diabetes 2006;55(6):1776-82.
2006: Karlsson Håkan K R; Ahlsén Maria; Zierath Juleen R; Wallberg-Henriksson Harriet; Koistinen Heikki A
Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients.
Diabetes 2006;55(5):1283-8.
2006: Bouzakri Karim; Karlsson Håkan K R; Vestergaard Henrik; Madsbad Sten; Christiansen Erik; Zierath Juleen R
IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.
Diabetes 2006;55(3):785-91.
2006: Bryzgalova G; Gao H; Ahren B; Zierath J R; Galuska D; Steiler T L; Dahlman-Wright K; Nilsson S; Gustafsson J-A; Efendic S; Khan A
Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver.
Diabetologia 2006;49(3):588-97.
2006: Nilsson Elisabeth C; Long Yun Chau; Martinsson Sofia; Glund Stephan; Garcia-Roves Pablo; Svensson L Thomas; Andersson Leif; Zierath Juleen R; Mahlapuu Margit
Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice.
The Journal of biological chemistry 2006;281(11):7244-52.
2006: Kannisto Katja; Chibalin Alexander; Glinghammar Björn; Zierath Juleen R; Hamsten Anders; Ehrenborg Ewa
Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.
International journal of molecular medicine 2006;17(1):45-52.
2006: Coffey Vernon G; Zhong Zhihui; Shield Anthony; Canny Benedict J; Chibalin Alexander V; Zierath Juleen R; Hawley John A
Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):190-2.
2006: Hawley John A; Hargreaves Mark; Zierath Juleen R
Signalling mechanisms in skeletal muscle: role in substrate selection and muscle adaptation.
Essays in biochemistry 2006;42():1-12.
2005: Barnes Brian R; Long Yun Chau; Steiler Tatiana L; Leng Ying; Galuska Dana; Wojtaszewski Jørgen F P; Andersson Leif; Zierath Juleen R
Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice.
Diabetes 2005;54(12):3484-9.
2005: Long Y C; Barnes B R; Mahlapuu M; Steiler T L; Martinsson S; Leng Y; Wallberg-Henriksson H; Andersson L; Zierath J R
Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle.
Diabetologia 2005;48(11):2354-64.
2005: Plomgaard Peter; Bouzakri Karim; Krogh-Madsen Rikke; Mittendorfer Bettina; Zierath Juleen R; Pedersen Bente K
Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation.
Diabetes 2005;54(10):2939-45.
2005: Bach Daniel; Naon Deborah; Pich Sara; Soriano Francesc X; Vega Nathalie; Rieusset Jennifer; Laville Martine; Guillet Christelle; Boirie Yves; Wallberg-Henriksson Harriet; Manco Melania; Calvani Menotti; Castagneto Marco; Palacín Manuel; Mingrone Geltrude; Zierath Juleen R; Vidal Hubert; Zorzano Antonio
Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.
Diabetes 2005;54(9):2685-93.
2005: Ryder Jeffrey W; Long Yun Chau; Nilsson Elisabeth; Mahlapuu Margit; Zierath Juleen R
Effects of calcineurin activation on insulin-, AICAR- and contraction-induced glucose transport in skeletal muscle.
The Journal of physiology 2005;567(Pt 2):379-86.
2005: Karlsson Håkan K R; Zierath Juleen R; Kane Susan; Krook Anna; Lienhard Gustav E; Wallberg-Henriksson Harriet
Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects.
Diabetes 2005;54(6):1692-7.
2005: Al-Khalili L; Forsgren M; Kannisto K; Zierath J R; Lönnqvist F; Krook A
Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1.
Diabetologia 2005;48(6):1173-9.
2005: Bouzakri Karim; Koistinen Heikki A; Zierath Juleen R
Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes.
Current diabetes reviews 2005;1(2):167-74.
2005: Barnes B R; Zierath J R
Role of AMP--activated protein kinase in the control of glucose homeostasis.
Current molecular medicine 2005;5(3):341-8.
2005: Barnes Brian R; Glund Stephan; Long Yun Chau; Hjälm Göran; Andersson Leif; Zierath Juleen R
5'-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):773-9.
2005: Karlsson Håkan K R; Hällsten Kirsti; Björnholm Marie; Tsuchida Hiroki; Chibalin Alexander V; Virtanen Kirsi A; Heinonen Olli J; Lönnqvist Fredrik; Nuutila Pirjo; Zierath Juleen R
Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.
Diabetes 2005;54(5):1459-67.
2005: Krämer David Kitz; Al-Khalili Lubna; Perrini Sebastio; Skogsberg Josefin; Wretenberg Per; Kannisto Katja; Wallberg-Henriksson Harriet; Ehrenborg Ewa; Zierath Juleen R; Krook Anna
Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.
Diabetes 2005;54(4):1157-63.
2005: Zierath Juleen R
Kinases in diabetes. Part II. 11-12 November 2004, Manchester, UK.
IDrugs : the investigational drugs journal 2005;8(2):121-3.
2005: Zierath Juleen R
Kinases in diabetes. Part I. 11-12 November 2004, Manchester, UK.
IDrugs : the investigational drugs journal 2005;8(2):118-20.
2004: Zierath Juleen R; Hawley John A
Skeletal muscle fiber type: influence on contractile and metabolic properties.
PLoS biology 2004;2(10):e348.
2004: Barnes Brian R; Marklund Stefan; Steiler Tatiana L; Walter Mark; Hjälm Göran; Amarger Valerie; Mahlapuu Margit; Leng Ying; Johansson Carina; Galuska Dana; Lindgren Kerstin; Abrink Magnus; Stapleton David; Zierath Juleen R; Andersson Leif
The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle.
The Journal of biological chemistry 2004;279(37):38441-7.
2004: Al-Khalili Lubna; Krook Anna; Zierath Juleen R; Cartee Gregory D
Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake.
American journal of physiology. Endocrinology and metabolism 2004;287(3):E553-7.
2004: Krook Anna; Wallberg-Henriksson Harriet; Zierath Juleen R
Sending the signal: molecular mechanisms regulating glucose uptake.
Medicine and science in sports and exercise 2004;36(7):1212-7.
2004: Karlsson Håkan K R; Nilsson Per-Anders; Nilsson Johnny; Chibalin Alexander V; Zierath Juleen R; Blomstrand Eva
Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise.
American journal of physiology. Endocrinology and metabolism 2004;287(1):E1-7.
2004: Leng Ying; Steiler Tatiana L; Zierath Juleen R
Effects of insulin, contraction, and phorbol esters on mitogen-activated protein kinase signaling in skeletal muscle from lean and ob/ob mice.
Diabetes 2004;53(6):1436-44.
2004: Al-Khalili Lubna; Chibalin Alexander V; Yu Mei; Sjödin Bertil; Nylén Carolina; Zierath Juleen R; Krook Anna
MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways.
American journal of physiology. Cell physiology 2004;286(6):C1410-6.
2004: Long Yun Chau; Widegren Ulrika; Zierath Juleen R
Exercise-induced mitogen-activated protein kinase signalling in skeletal muscle.
The Proceedings of the Nutrition Society 2004;63(2):227-32.
2004: Leng Ying; Karlsson Håkan K R; Zierath Juleen R
Insulin signaling defects in type 2 diabetes.
Reviews in endocrine & metabolic disorders 2004;5(2):111-7.
2004: Storgaard Heidi; Jensen Christine B; Björnholm Marie; Song Xiao Mei; Madsbad Sten; Zierath Juleen R; Vaag Allan A
Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2004;89(3):1301-11.
2004: Mahlapuu Margit; Johansson Carina; Lindgren Kerstin; Hjälm Göran; Barnes Brian R; Krook Anna; Zierath Juleen R; Andersson Leif; Marklund Stefan
Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2004;286(2):E194-200.
2004: Hawley John A; Zierath Juleen R
Integration of metabolic and mitogenic signal transduction in skeletal muscle.
Exercise and sport sciences reviews 2004;32(1):4-8.
2004: Koistinen Heikki A; Forsgren Margareta; Wallberg-Henriksson Harriet; Zierath Juleen R
Insulin action on expression of novel adipose genes in healthy and type 2 diabetic subjects.
Obesity research 2004;12(1):25-31.
2004: Perrini Sebastio; Henriksson Jan; Zierath Juleen R; Widegren Ulrika
Exercise-induced protein kinase C isoform-specific activation in human skeletal muscle.
Diabetes 2004;53(1):21-4.
2003: Steiler Tatiana L; Galuska Dana; Leng Ying; Chibalin Alexander V; Gilbert Marc; Zierath Juleen R
Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats.
Endocrinology 2003;144(12):5259-67.
2003: Ryder Jeffrey W; Bassel-Duby Rhonda; Olson Eric N; Zierath Juleen R
Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways.
The Journal of biological chemistry 2003;278(45):44298-304.
2003: Koistinen H A; Chibalin A V; Zierath J R
Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients.
Diabetologia 2003;46(10):1324-8.
2003: Zierath Juleen R; Kawano Yuichi
The effect of hyperglycaemia on glucose disposal and insulin signal transduction in skeletal muscle.
Best practice & research. Clinical endocrinology & metabolism 2003;17(3):385-98.
2003: Kemppainen Jukka; Tsuchida Hiroki; Stolen Kira; Karlsson Håkan; Björnholm Marie; Heinonen Olli J; Nuutila Pirjo; Krook Anna; Knuuti Juhani; Zierath Juleen R
Insulin signalling and resistance in patients with chronic heart failure.
The Journal of physiology 2003;550(Pt 1):305-15.
2003: Al-Khalili L; Chibalin A V; Kannisto K; Zhang B B; Permert J; Holman G D; Ehrenborg E; Ding V D H; Zierath J R; Krook A
Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content.
Cellular and molecular life sciences : CMLS 2003;60(5):991-8.
2003: Koistinen Heikki A; Galuska Dana; Chibalin Alexander V; Yang Jing; Zierath Juleen R; Holman Geoffrey D; Wallberg-Henriksson Harriet
5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.
Diabetes 2003;52(5):1066-72.
2003: Bach Daniel; Pich Sara; Soriano Francesc X; Vega Nathalie; Baumgartner Bernhard; Oriola Josep; Daugaard Jens R; Lloberas Jorge; Camps Marta; Zierath Juleen R; Rabasa-Lhoret Rémi; Wallberg-Henriksson Harriet; Laville Martine; Palacín Manuel; Vidal Hubert; Rivera Francisca; Brand Martin; Zorzano Antonio
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity.
The Journal of biological chemistry 2003;278(19):17190-7.
2003: Isaksson Bengt; Strömmer Lisa; Friess Helmut; Büchler Markus W; Herrington Margery K; Wang Feng; Zierath Juleen R; Wallberg-Henriksson Harriet; Larsson Jörgen; Permert Johan
Impaired insulin action on phosphatidylinositol 3-kinase activity and glucose transport in skeletal muscle of pancreatic cancer patients.
Pancreas 2003;26(2):173-7.
2003: Yu Mei; Stepto Nigel K; Chibalin Alexander V; Fryer Lee G D; Carling Dave; Krook Anna; Hawley John A; Zierath Juleen R
Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise.
The Journal of physiology 2003;546(Pt 2):327-35.
2002: Björnholm M; He A R; Attersand A; Lake S; Liu S C H; Lienhard G E; Taylor S; Arner P; Zierath J R
Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans.
Diabetologia 2002;45(12):1697-702.
2002: Tsuchida Hiroki; Björnholm Marie; Fernström Maria; Galuska Dana; Johansson Per; Wallberg-Henriksson Harriet; Zierath Juleen R; Lake Staffan; Krook Anna
Gene expression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in skeletal muscle from type 2 diabetic subjects.
Pflügers Archiv : European journal of physiology 2002;445(1):25-31.
2002: Barnes Brian R; Ryder Jeffrey W; Steiler Tatiana L; Fryer Lee G D; Carling David; Zierath Juleen R
Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction.
Diabetes 2002;51(9):2703-8.
2002: Ceddia Rolando B; Koistinen Heikki A; Zierath Juleen R; Sweeney Gary
Analysis of paradoxical observations on the association between leptin and insulin resistance.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1163-76.
2002: Zierath Juleen R
Invited review: Exercise training-induced changes in insulin signaling in skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(2):773-81.
2002: Zierath Juleen R; Wallberg-Henriksson Harriet
From receptor to effector: insulin signal transduction in skeletal muscle from type II diabetic patients.
Annals of the New York Academy of Sciences 2002;967():120-34.
2002: Song X M; Fiedler M; Galuska D; Ryder J W; Fernström M; Chibalin A V; Wallberg-Henriksson H; Zierath J R
5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice.
Diabetologia 2002;45(1):56-65.
2002: Koistinen H A; Zierath J R
Regulation of glucose transport in human skeletal muscle.
Annals of medicine 2002;34(6):410-8.
2001: Storgaard H; Song X M; Jensen C B; Madsbad S; Björnholm M; Vaag A; Zierath J R
Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].
Diabetes 2001;50(12):2770-8.
2001: Kawano Y; Ryder J W; Rincon J; Zierath J R; Krook A; Wallberg-Henriksson H
Evidence against high glucose as a mediator of ERK1/2 or p38 MAPK phosphorylation in rat skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2001;281(6):E1255-9.
2001: Yu M; Blomstrand E; Chibalin A V; Krook A; Zierath J R
Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle.
The Journal of physiology 2001;536(Pt 1):273-82.
2001: Chibalin A V; Kovalenko M V; Ryder J W; Féraille E; Wallberg-Henriksson H; Zierath J R
Insulin- and glucose-induced phosphorylation of the Na(+),K(+)-adenosine triphosphatase alpha-subunits in rat skeletal muscle.
Endocrinology 2001;142(8):3474-82.
2001: Wallberg-Henriksson H; Zierath J R
GLUT4: a key player regulating glucose homeostasis? Insights from transgenic and knockout mice (review).
Molecular membrane biology 2001;18(3):205-11.
2001: Widegren U; Ryder J W; Zierath J R
Mitogen-activated protein kinase signal transduction in skeletal muscle: effects of exercise and muscle contraction.
Acta physiologica Scandinavica 2001;172(3):227-38.
2001: Ryder J W; Portocarrero C P; Song X M; Cui L; Yu M; Combatsiaris T; Galuska D; Bauman D E; Barbano D M; Charron M J; Zierath J R; Houseknecht K L
Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression.
Diabetes 2001;50(5):1149-57.
2001: Tsao T S; Li J; Chang K S; Stenbit A E; Galuska D; Anderson J E; Zierath J R; McCarter R J; Charron M J
Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):958-69.
2001: Ryder J W; Chibalin A V; Zierath J R
Intracellular mechanisms underlying increases in glucose uptake in response to insulin or exercise in skeletal muscle.
Acta physiologica Scandinavica 2001;171(3):249-57.
2001: Yu M; Blomstrand E; Chibalin A V; Wallberg-Henriksson H; Zierath J R; Krook A
Exercise-associated differences in an array of proteins involved in signal transduction and glucose transport.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;90(1):29-34.
2000: Krook A; Widegren U; Jiang X J; Henriksson J; Wallberg-Henriksson H; Alessi D; Zierath J R
Effects of exercise on mitogen- and stress-activated kinase signal transduction in human skeletal muscle.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(5):R1716-21.
2000: Zierath J R; Krook A; Wallberg-Henriksson H
Insulin action and insulin resistance in human skeletal muscle.
Diabetologia 2000;43(7):821-35.
2000: Ryder J W; Yang J; Galuska D; Rincón J; Björnholm M; Krook A; Lund S; Pedersen O; Wallberg-Henriksson H; Zierath J R; Holman G D
Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients.
Diabetes 2000;49(4):647-54.
2000: Krook A; Björnholm M; Galuska D; Jiang X J; Fahlman R; Myers M G; Wallberg-Henriksson H; Zierath J R
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients.
Diabetes 2000;49(2):284-92.
2000: Ryder J W; Fahlman R; Wallberg-Henriksson H; Alessi D R; Krook A; Zierath J R
Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement Of the mitogen- and stress-activated protein kinase 1.
The Journal of biological chemistry 2000;275(2):1457-62.
2000: Chibalin A V; Yu M; Ryder J W; Song X M; Galuska D; Krook A; Wallberg-Henriksson H; Zierath J R
Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):38-43.
1999: Rincón J; Galuska D; Ryder J W; Kawano Y; Wallberg-Henriksson H; Gorrod J W; Zierath J R
Effect of the nicotine metabolite 5'-hydroxycotinine on glucose transport and glycogen synthase activity in rat skeletal muscle.
Pflügers Archiv : European journal of physiology 1999;439(1-2):130-3.
1999: Song X M; Ryder J W; Kawano Y; Chibalin A V; Krook A; Zierath J R
Muscle fiber type specificity in insulin signal transduction.
The American journal of physiology 1999;277(6 Pt 2):R1690-6.
1999: Ryder J W; Kawano Y; Galuska D; Fahlman R; Wallberg-Henriksson H; Charron M J; Zierath J R
Postexercise glucose uptake and glycogen synthesis in skeletal muscle from GLUT4-deficient mice.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(15):2246-56.
1999: Ryder J W; Kawano Y; Chibalin A V; Rincón J; Tsao T S; Stenbit A E; Combatsiaris T; Yang J; Holman G D; Charron M J; Zierath J R
In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle.
The Biochemical journal 1999;342 ( Pt 2)():321-8.
1999: Kawano Y; Rincon J; Soler A; Ryder J W; Nolte L A; Zierath J R; Wallberg-Henriksson H
Changes in glucose transport and protein kinase Cbeta(2) in rat skeletal muscle induced by hyperglycaemia.
Diabetologia 1999;42(9):1071-9.
1999: Hjeltnes N; Fernström M; Zierath J R; Krook A
Regulation of UCP2 and UCP3 by muscle disuse and physical activity in tetraplegic subjects.
Diabetologia 1999;42(7):826-30.
1999: Rincón J; Krook A; Galuska D; Wallberg-Henriksson H; Zierath J R
Altered skeletal muscle glucose transport and blood lipid levels in habitual cigarette smokers.
Clinical physiology (Oxford, England) 1999;19(2):135-42.
1999: Song X M; Kawano Y; Krook A; Ryder J W; Efendic S; Roth R A; Wallberg-Henriksson H; Zierath J R
Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats.
Diabetes 1999;48(3):664-70.
1998: Hjeltnes N; Galuska D; Björnholm M; Aksnes A K; Lannem A; Zierath J R; Wallberg-Henriksson H
Exercise-induced overexpression of key regulatory proteins involved in glucose uptake and metabolism in tetraplegic persons: molecular mechanism for improved glucose homeostasis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(15):1701-12.
1998: Zierath J R; Livingston J N; Thörne A; Bolinder J; Reynisdottir S; Lönnqvist F; Arner P
Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway.
Diabetologia 1998;41(11):1343-54.
1998: Widegren U; Jiang X J; Krook A; Chibalin A V; Björnholm M; Tally M; Roth R A; Henriksson J; Wallberg-henriksson H; Zierath J R
Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(13):1379-89.
1998: Krook A; Digby J; O'Rahilly S; Zierath J R; Wallberg-Henriksson H
Uncoupling protein 3 is reduced in skeletal muscle of NIDDM patients.
Diabetes 1998;47(9):1528-31.
1998: Krook A; Roth R A; Jiang X J; Zierath J R; Wallberg-Henriksson H
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects.
Diabetes 1998;47(8):1281-6.
1998: Zierath J R; Tsao T S; Stenbit A E; Ryder J W; Galuska D; Charron M J
Restoration of hypoxia-stimulated glucose uptake in GLUT4-deficient muscles by muscle-specific GLUT4 transgenic complementation.
The Journal of biological chemistry 1998;273(33):20910-5.
1998: Strömmer L; Permert J; Arnelo U; Koehler C; Isaksson B; Larsson J; Lundkvist I; Björnholm M; Kawano Y; Wallberg-Henriksson H; Zierath J R
Skeletal muscle insulin resistance after trauma: insulin signaling and glucose transport.
The American journal of physiology 1998;275(2 Pt 1):E351-8.
1998: Wallberg-Henriksson H; Rincon J; Zierath J R
Exercise in the management of non-insulin-dependent diabetes mellitus.
Sports medicine (Auckland, N.Z.) 1998;25(1):25-35.
1998: Zierath J R; Frevert E U; Ryder J W; Berggren P O; Kahn B B
Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes.
Diabetes 1998;47(1):1-4.
1997: Krook A; Kawano Y; Song X M; Efendic S; Roth R A; Wallberg-Henriksson H; Zierath J R
Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats.
Diabetes 1997;46(12):2110-4.
1997: Lund S; Holman G D; Zierath J R; Rincon J; Nolte L A; Clark A E; Schmitz O; Pedersen O; Wallberg-Henriksson H
Effect of insulin on GLUT4 cell surface content and turnover rate in human skeletal muscle as measured by the exofacial bis-mannose photolabeling technique.
Diabetes 1997;46(12):1965-9.
1997: Shepherd P R; Nave B T; Rincon J; Haigh R J; Foulstone E; Proud C; Zierath J R; Siddle K; Wallberg-Henriksson H
Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism.
Diabetologia 1997;40(10):1172-7.
1997: Lund S; Pedersen O; Holman G D; Clark A E; Zierath J R; Wallberg-Henriksson H
GLUT4 translocation in human muscle strips.
Biochemical Society transactions 1997;25(3):466S.
1997: Charron M J; Katz E B; Zierath J R
Metabolic and molecular consequences of modifying GLUT4 expression in skeletal muscle.
Biochemical Society transactions 1997;25(3):963-8.
1997: Tsao T S; Stenbit A E; Li J; Houseknecht K L; Zierath J R; Katz E B; Charron M J
Muscle-specific transgenic complementation of GLUT4-deficient mice. Effects on glucose but not lipid metabolism.
The Journal of clinical investigation 1997;100(3):671-7.
1997: Shepherd P R; Navé B T; Rincon J; Nolte L A; Bevan A P; Siddle K; Zierath J R; Wallberg-Henriksson H
Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle.
The Journal of biological chemistry 1997;272(30):19000-7.
1997: Björnholm M; Kawano Y; Lehtihet M; Zierath J R
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation.
Diabetes 1997;46(3):524-7.
1997: Zierath J R; Houseknecht K L; Gnudi L; Kahn B B
High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect.
Diabetes 1997;46(2):215-23.
1996: Zierath J R; He L; Gumà A; Odegoard Wahlström E; Klip A; Wallberg-Henriksson H
Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM.
Diabetologia 1996;39(10):1180-9.
1996: Wahren J; Johansson B L; Wallberg-Henriksson H; Linde B; Fernqvist-Forbes E; Zierath J R
C-peptide revisited--new physiological effects and therapeutic implications.
Journal of internal medicine 1996;240(3):115-24.
1996: Aksnes A K; Hjeltnes N; Wahlström E O; Katz A; Zierath J R; Wallberg-Henriksson H
Intact glucose transport in morphologically altered denervated skeletal muscle from quadriplegic patients.
The American journal of physiology 1996;271(3 Pt 1):E593-600.
1996: Houseknecht K L; Zhu A X; Gnudi L; Hamann A; Zierath J R; Tozzo E; Flier J S; Kahn B B
Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin.
The Journal of biological chemistry 1996;271(19):11347-55.
1996: Rincon J; Holmäng A; Wahlström E O; Lönnroth P; Björntorp P; Zierath J R; Wallberg-Henriksson H
Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment.
Diabetes 1996;45(5):615-21.
1996: Zierath J R; Handberg A; Tally M; Wallberg-Henriksson H
C-peptide stimulates glucose transport in isolated human skeletal muscle independent of insulin receptor and tyrosine kinase activation.
Diabetologia 1996;39(3):306-13.
1995: Nolte L A; Rincón J; Wahlström E O; Craig B W; Zierath J R; Wallberg-Henriksson H
Hyperglycemia activates glucose transport in rat skeletal muscle via a Ca(2+)-dependent mechanism.
Diabetes 1995;44(11):1345-8.
1995: Zierath J R; Nolte L A; Wahlström E; Galuska D; Shepherd P R; Kahn B B; Wallberg-Henriksson H
Carrier-mediated fructose uptake significantly contributes to carbohydrate metabolism in human skeletal muscle.
The Biochemical journal 1995;311 ( Pt 2)():517-21.
1995: Gumà A; Zierath J R; Wallberg-Henriksson H; Klip A
Insulin induces translocation of GLUT-4 glucose transporters in human skeletal muscle.
The American journal of physiology 1995;268(4 Pt 1):E613-22.
1995: Nolte L A; Abdel-Halim S M; Martin I K; Guenifi A; Zierath J R; Ostenson C G; Wallberg-Henriksson H
Development of decreased insulin-induced glucose transport in skeletal muscle of glucose-intolerant hybrids of diabetic GK rats.
Clinical science (London, England : 1979) 1995;88(3):301-6.
1994: Galuska D; Nolte L; Wahlström E; Smedegaard Kristensen J S; Wallberg-Henriksson H; Zierath J R
Effects of non-esterified fatty acids on insulin-stimulated glucose transport in isolated skeletal muscle from patients with type 2 (non-insulin-dependent) diabetes mellitus.
Acta diabetologica 1994;31(3):169-72.
1994: Galuska D; Nolte L A; Zierath J R; Wallberg-Henriksson H
Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM.
Diabetologia 1994;37(8):826-32.
1994: Nolte L A; Galuska D; Martin I K; Zierath J R; Wallberg-Henriksson H
Elevated free fatty acid levels inhibit glucose phosphorylation in slow-twitch rat skeletal muscle.
Acta physiologica Scandinavica 1994;151(1):51-9.
1994: Zierath J R; Galuska D; Nolte L A; Thörne A; Kristensen J S; Wallberg-Henriksson H
Effects of glycaemia on glucose transport in isolated skeletal muscle from patients with NIDDM: in vitro reversal of muscular insulin resistance.
Diabetologia 1994;37(3):270-7.
1994: Norgren S; Zierath J; Wedell A; Wallberg-Henriksson H; Luthman H
Regulation of human insulin receptor RNA splicing in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1465-9.
1994: Johansson U; Eriksson L S; Galuska D; Zierath J R; Wallberg-Henriksson H
Insulin action on glucose transport in isolated skeletal muscle from patients with liver cirrhosis.
Scandinavian journal of gastroenterology 1994;29(1):71-6.
1993: Norgren S; Zierath J; Galuska D; Wallberg-Henriksson H; Luthman H
Differences in the ratio of RNA encoding two isoforms of the insulin receptor between control and NIDDM patients. The RNA variant without Exon 11 predominates in both groups.
Diabetes 1993;42(5):675-81.
1992: Zierath J R; Wallberg-Henriksson H
Exercise training in obese diabetic patients. Special considerations.
Sports medicine (Auckland, N.Z.) 1992;14(3):171-89.
1992: Zierath J R; Bang P; Galuska D; Hall K; Wallberg-Henriksson H
Insulin-like growth factor II stimulates glucose transport in human skeletal muscle.
FEBS letters 1992;307(3):379-82.
1992: Zierath J R; Galuska D; Engström A; Johnson K H; Betsholtz C; Westermark P; Wallberg-Henriksson H
Human islet amyloid polypeptide at pharmacological levels inhibits insulin and phorbol ester-stimulated glucose transport in in vitro incubated human muscle strips.
Diabetologia 1992;35(1):26-31.
1991: Zierath J R; Galuska D; Johansson B L; Wallberg-Henriksson H
Effect of human C-peptide on glucose transport in in vitro incubated human skeletal muscle.
Diabetologia 1991;34(12):899-901.
1991: Galuska D; Zierath J; Thörne A; Sonnenfeld T; Wallberg-Henriksson H
Metformin increases insulin-stimulated glucose transport in insulin-resistant human skeletal muscle.
Diabète & métabolisme 1991;17(1 Pt 2):159-63.

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