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Juleen Zierath

Research Profile

Anatomy

Muscle, Skeletal

Chemicals & Drugs

Physiology

Disorders

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TOP 3
Sojeong Ka; Ellen Markljung; Svante Pääbo; Henrik Ring; Paul B Siegel; Per Wahlberg; Juleen R Zierath; Frank W Albert; Leif Andersson; D Michael Denbow; Pablo M Garcia-Roves; Mohammad Harun-Or-Rashid; Finn Hallböök
Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight.
Henriette Kirchner; Anna Krook; Megan E Osler; Juleen R Zierath
Epigenetic flexibility in metabolic regulation: disease cause and prevention?
Romain Barres; Francisc R Kantor; Henriette Kirchner; Anna Krook; Erik Näslund; Morten Rasmussen; Jie Yan; Juleen R Zierath
Weight loss after gastric bypass surgery in human obesity remodels promoter methylation.

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All Publications

2013: Sojeong Ka; Ellen Markljung; Svante Pääbo; Henrik Ring; Paul B Siegel; Per Wahlberg; Juleen R Zierath; Frank W Albert; Leif Andersson; D Michael Denbow; Pablo M Garcia-Roves; Mohammad Harun-Or-Rashid; Finn Hallböök
Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight.
Physiological genomics 2013;45(9):367-76.
2013: Henriette Kirchner; Anna Krook; Megan E Osler; Juleen R Zierath
Epigenetic flexibility in metabolic regulation: disease cause and prevention?
Trends in cell biology 2013;23(5):203-9.
2013: Romain Barres; Francisc R Kantor; Henriette Kirchner; Anna Krook; Erik Näslund; Morten Rasmussen; Jie Yan; Juleen R Zierath
Weight loss after gastric bypass surgery in human obesity remodels promoter methylation.
Cell reports 2013;3(4):1020-7.
2013: Brendan Egan; Juleen R Zierath
Exercise metabolism and the molecular regulation of skeletal muscle adaptation.
Cell metabolism 2013;17(2):162-84.
2013: Lake Q Jiang; Ubiratan F Machado; Juleen R Zierath; Daniella E Duque-Guimaraes; Anna Krook
Altered response of skeletal muscle to IL-6 in type 2 diabetic patients.
Diabetes 2013;62(2):355-61.
2013: Fredirick Mashili; Alexander V Chibalin; Anna Krook; Juleen R Zierath
Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes.
Diabetes 2013;62(2):457-65.
2013: Thais de Castro Barbosa; Lake Q Jiang; Juleen R Zierath; Maria Tereza Nunes
L-Arginine enhances glucose and lipid metabolism in rat L6 myotubes via the NO/ c-GMP pathway.
Metabolism: clinical and experimental 2013;62(1):79-89.
2013: T Fritz; Anna Krook; P Lundström; F Mashili; M Osler; F L M Szekeres; P Wändell; Kenneth Caidahl; C G Östenson; Juleen R Zierath
Effects of Nordic walking on cardiovascular risk factors in overweight individuals with type 2 diabetes, impaired or normal glucose tolerance.
Diabetes/metabolism research and reviews 2013;29(1):25-32.
2012: Ferenc Szekeres; Robby Z Tom; Hadi Al-Hasani; Marie Björnholm; Alexandra Chadt; Alexander V Chibalin; Atul Deshmukh; Juleen R Zierath
The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism.
American journal of physiology. Endocrinology and metabolism 2012;303(4):E524-33.
2012: Boubacar Benziane; Marie Björnholm; Reginald L Austin; Olga Kotova; Sergej Pirkmajer; Benoit Viollet; Juleen R Zierath; Alexander V Chibalin
Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells.
The Journal of biological chemistry 2012;287(28):23451-63.
2012: Maria H Holmström; Eduardo Iglesias-Gutierrez; Juleen R Zierath; Pablo M Garcia-Roves
Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes.
American journal of physiology. Endocrinology and metabolism 2012;302(6):E731-9.
2012: Romain Barrès; Kenneth Caidahl; Brendan Egan; Tomas Fritz; Anna Krook; Donal J O'Gorman; Morten Rasmussen; Jonas Thue Treebak; Jie Yan; Juleen R Zierath
Acute exercise remodels promoter methylation in human skeletal muscle.
Cell metabolism 2012;15(3):405-11.
2012: Sameer S Kulkarni; Tomas Fritz; Anna Krook; Firoozeh Salehzadeh; Juleen R Zierath; Megan E Osler
Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus.
Metabolism: clinical and experimental 2012;61(2):175-85.
2012: Juleen R Zierath
Remembering our classics: then and now.
Diabetologia 2012;55(1):1-2.
2011: Jie Yan; Juleen R Zierath; Romain Barrès
Evidence for non-CpG methylation in mammals.
Experimental cell research 2011;317(18):2555-61.
2011: Sameer S Kulkarni; Ferenc Szekeres; Alexander V Chibalin; Håkan Karlsson; Anna Krook; Juleen R Zierath
Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle.
The Journal of biological chemistry 2011;286(40):34567-74.
2011: Juleen R Zierath; Romain E Barrès
Nutritional status affects the epigenomic profile of peripheral blood cells.
Epigenomics 2011;3(3):259-60.
2011: Brendan Egan; Paul Dowling; Paul L O'Connor; Michael Henry; Paula Meleady; Juleen R Zierath; Donal O'Gorman
2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training.
Proteomics 2011;11(8):1413-28.
2011: Romain Barres; Juleen R Zierath
DNA methylation in metabolic disorders.
The American journal of clinical nutrition 2011;93(4):897S-900.
2011: Fredirick L Mashili; Reginald Austin; Atul S Deshmukh; Tomas Fritz; Kenneth Caidahl; Katrin Bergdahl; Juleen R Zierath; Alexander V Chibalin; David E Moller; Alexei Kharitonenkov; Anna Krook
Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity.
Diabetes/metabolism research and reviews 2011;27(3):286-97.
2011: Frauke S Czepluch; Romain Barrès; Kenneth Caidahl; Servé Olieslagers; Anna Krook; Anette Rickenlund; Juleen R Zierath; Johannes Waltenberger
Strenuous physical exercise adversely affects monocyte chemotaxis.
Thrombosis and haemostasis 2011;105(1):122-30.
2011: B F Vind; C Pehmøller; Jonas T Treebak; Jesper B Birk; M Hey-Mogensen; Henning Beck-Nielsen; Juleen R Zierath; Jørgen F P Wojtaszewski; Kurt Højlund
Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training.
Diabetologia 2011;54(1):157-67.
2010: Juleen R Zierath; Anna Krook
[Molecular mechanisms underlying insulin resistance in skeletal muscle].
Läkartidningen 2010;107(45):2802-5.
2010: Xiaoli Feng; Jie Yan; Yibiao Wang; Juleen R Zierath; Magnus Nordenskjöld; Jan-Inge Henter; Bengt Fadeel; Chengyun Zheng
The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells.
Molecular immunology 2010;47(14):2388-96.
2010: Atul Deshmukh; Yun Chau Long; T de Castro Barbosa; Håkan Karlsson; Stephan Glund; W J Zavadoski; E M Gibbs; Heikki A Koistinen; Harriet Wallberg-Henriksson; Juleen R Zierath
Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle.
Diabetologia 2010;53(6):1142-50.
2010: Brendan Egan; Brian P Carson; Pablo M Garcia-Roves; Alexander V Chibalin; Fiona M Sarsfield; Niall Barron; Noel McCaffrey; niall moyna; Juleen R Zierath; Donal O'Gorman
Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle.
The Journal of physiology 2010;588(Pt 10):1779-90.
2010: Peter Sogaard; Ferenc Szekeres; Pablo M Garcia-Roves; dennis larsson; Alexander V Chibalin; Juleen R Zierath
Spatial insulin signalling in isolated skeletal muscle preparations.
Journal of cellular biochemistry 2010;109(5):943-9.
2010: Carles Cantó; Lake Q Jiang; Atul S Deshmukh; Chikage Mataki; Agnes Coste; Marie Lagouge; Juleen R Zierath; Johan Auwerx
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle.
Cell metabolism 2010;11(3):213-9.
2010: Lake Q Jiang; Pablo M Garcia-Roves; Thais de Castro Barbosa; Juleen R Zierath
Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity.
American journal of physiology. Endocrinology and metabolism 2010;298(1):E8-E16.
2009: Ellen Markljung; Lin Jiang; Jacob D Jaffe; Tarjei S Mikkelsen; Ola Wallerman; Martin Larhammar; Xiaolan Zhang; Li Wang; Veronica Saenz-Vash; Andreas Gnirke; Anders M Lindroth; Romain Barrés; Jie Yan; Siv Strömberg; Sachinandan De; Fredrik Pontén; Eric S Lander; Steven A Carr; Juleen R Zierath; Klas Kullander; Claes Wadelius; Kerstin Lindblad-Toh; Göran Andersson; Göran Hjälm; Leif Andersson
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
PLoS biology 2009;7(12):e1000256.
2009: Boubacar Benziane; Marie Björnholm; Louise Lantier; Benoit Viollet; Juleen R Zierath; Alexander V Chibalin
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase.
American journal of physiology. Cell physiology 2009;297(6):C1554-66.
2009: Atul Deshmukh; Stephan Glund; Robby Z Tom; Juleen R Zierath
Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2009;297(6):E1388-94.
2009: Grantley R Peck; Jose A Chavez; William G Roach; Bogdan A Budnik; William Stratton Lane; Håkan Karlsson; Juleen R Zierath; Gustav E Lienhard
Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation.
The Journal of biological chemistry 2009;284(44):30016-23.
2009: A Rune; M E Osler; T Fritz; Juleen R Zierath
Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.
Diabetologia 2009;52(10):2182-9.
2009: Romain Barrès; Megan E Osler; Jie Yan; Anna Rune; Tomas Fritz; Kenneth Caidahl; Anna Krook; Juleen R Zierath
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.
Cell metabolism 2009;10(3):189-98.
2009: Anna Krook; Juleen R Zierath
Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA.
Diabetologia 2009;52(7):1231-9.
2009: Brendan Egan; Juleen R Zierath
Hunting for the SNARK in metabolic disease.
American journal of physiology. Endocrinology and metabolism 2009;296(5):E969-72.
2009: Jonas T Treebak; Christian Frøsig; C Pehmøller; S Chen; S J Maarbjerg; N Brandt; C MacKintosh; Juleen R Zierath; D Grahame Hardie; Bente Kiens; Erik A Richter; Henriette Pilegaard; Jørgen F P Wojtaszewski
Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle.
Diabetologia 2009;52(5):891-900.
2009: Ariane Sultan; Daniela Strodthoff; Anna-Karin L Robertson; Gabrielle Paulsson-Berne; Jeremy Fauconnier; Paolo Parini; Mikael Rydén; Nicolas Thierry-Mieg; Maria E Johansson; Alexander V Chibalin; Juleen R Zierath; Peter Arner; Göran K Hansson
T cell-mediated inflammation in adipose tissue does not cause insulin resistance in hyperlipidemic mice.
Circulation research 2009;104(8):961-8.
2009: Harriet Wallberg-Henriksson; Juleen R Zierath
A new twist on brown fat metabolism.
Cell 2009;137(1):22-4.
2009: Håkan Karlsson; Alexander V Chibalin; Heikki A Koistinen; Jing Yang; Francoise Koumanov; Harriet Wallberg-Henriksson; Juleen R Zierath; Geoffrey D Holman
Kinetics of GLUT4 trafficking in rat and human skeletal muscle.
Diabetes 2009;58(4):847-54.
2009: Stephan Glund; Jonas T Treebak; Yun Chau Long; Romain Barres; Benoit Viollet; Jørgen F P Wojtaszewski; Juleen R Zierath
Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle.
Endocrinology 2009;150(2):600-6.
2008: Boubacar Benziane; Timothy J Burton; Brendan Scanlan; Dana Galuska; Benedict J Canny; Alexander V Chibalin; Juleen R Zierath; Nigel K Stepto
Divergent cell signaling after short-term intensified endurance training in human skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2008;295(6):E1427-38.
2008: Alexandra Chadt; Katja Leicht; Atul Deshmukh; Lake Q Jiang; Stephan Scherneck; Ulrike Bernhardt; Tanja Dreja; Heike Vogel; Katja Schmolz; Reinhart Kluge; Juleen R Zierath; Claus Hultschig; Rob Hoeben; Annette Schürmann; Hans-Georg Joost; Hadi Al-Hasani
Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity.
Nature genetics 2008;40(11):1354-9.
2008: L Lundholm; Galina Bryzgalova; Hui Gao; N Portwood; S Fält; K D Berndt; A Dicker; D Galuska; Juleen R Zierath; Jan-�ke GUSTAFSSON; Suad Efendic; Karin Dahlman-Wright; Akhtar Khan
The estrogen receptor {alpha}-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms.
The Journal of endocrinology 2008;199(2):275-86.
2008: Elaine Vieira; Elisabeth C Nilsson; Annika Nerstedt; Mattias Ormestad; Yun Chau Long; Pablo M Garcia-Roves; Juleen R Zierath; Margit Mahlapuu
Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2008;295(5):E1032-7.
2008: Heidi Kuoppamaa; Paulina Skrobuk; Maarit Sihvo; Anne Hiukka; Alexander V Chibalin; Juleen R Zierath; Heikki A Koistinen
Globular adiponectin stimulates glucose transport in type 2 diabetic muscle.
Diabetes/metabolism research and reviews 2008;24(7):554-62.
2008: Atul Deshmukh; John A Hawley; Juleen R Zierath
Exercise-induced phospho-proteins in skeletal muscle.
International journal of obesity (2005) 2008;32 Suppl 4():S18-23.
2008: Yun Chau Long; Juleen R Zierath
Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2008;295(3):E545-52.
2008: Reginald Austin; Anna Rune; Karim Bouzakri; Juleen R Zierath; Anna Krook
siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.
Diabetes 2008;57(8):2066-73.
2008: Over Cabrera; M Caroline Jacques-Silva; Stephan Speier; Shao-Nian Yang; Martin Köhler; Alberto Fachado; Elaine Vieira; Juleen R Zierath; Richard Kibbey; Dora Berman-Weinberg; Norma S Kenyon; Camillo Ricordi; Diego Caicedo-Vierkant; Per-Olof Berggren
Glutamate is a positive autocrine signal for glucagon release.
Cell metabolism 2008;7(6):545-54.
2008: Karim Bouzakri; Reginald Austin; Anna Rune; Michael E Lassman; Pablo M Garcia-Roves; Joel P Berger; Anna Krook; Alexander V Chibalin; Bei B Zhang; Juleen R Zierath
Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle.
Diabetes 2008;57(6):1508-16.
2008: Atul S Deshmukh; Jonas T Treebak; Yun Chau Long; Benoit Viollet; Jørgen F P Wojtaszewski; Juleen R Zierath
Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling.
Molecular endocrinology (Baltimore, Md.) 2008;22(5):1105-12.
2008: Megan E Osler; Juleen R Zierath
Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle.
Endocrinology 2008;149(3):935-41.
2008: Alexander V Chibalin; Ying Leng; Elaine Vieira; Anna Krook; Marie Björnholm; Yun Chau Long; Olga Kotova; Zhihui Zhong; Fumio Sakane; Tatiana Steiler; Carolina Nylén; Jianjun Wang; Markku Laakso; Matthew K Topham; Marc Gilbert; Harriet Wallberg-Henriksson; Juleen R Zierath
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.
Cell 2008;132(3):375-86.
2008: Juleen R Zierath
Xth International Symposium on insulin receptors and insulin action.
Acta physiologica (Oxford, England) 2008;192(1):1.
2007: M E Osler; Juleen R Zierath
Fighting the battle of the bulge: exercise training in early-onset type 2 diabetes.
Diabetologia 2007;50(7):1362-4.
2007: Stephan Glund; Atul Deshmukh; Yun Chau Long; Theodore Moller; Heikki A Koistinen; Kenneth Caidahl; Juleen R Zierath; Anna Krook
Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.
Diabetes 2007;56(6):1630-7.
2007: Hemang Parikh; Emma Carlsson; William A Chutkow; Lovisa E Johansson; Heidi Storgaard; Pernille Poulsen; Richa Saxena; Christine Ladd; P Christian Schulze; Michael J Mazzini; Christine B Jensen; Anna Krook; Marie Björnholm; Hans Tornqvist; Juleen R Zierath; Martin Ridderstråle; David Altshuler; Richard T Lee; Allan Vaag; Leif C Groop; Vamsi K Mootha
TXNIP regulates peripheral glucose metabolism in humans.
PLoS medicine 2007;4(5):e158.
2007: Karim Bouzakri; Juleen R Zierath
MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.
The Journal of biological chemistry 2007;282(11):7783-9.
2007: Juleen R Zierath
The path to insulin resistance: paved with ceramides?
Cell metabolism 2007;5(3):161-3.
2007: Yun Chau Long; Stephan Glund; Pablo M Garcia-Roves; Juleen R Zierath
Calcineurin regulates skeletal muscle metabolism via coordinated changes in gene expression.
The Journal of biological chemistry 2007;282(3):1607-14.
2007: Håkan Karlsson; Juleen R Zierath
Insulin signaling and glucose transport in insulin resistant human skeletal muscle.
Cell biochemistry and biophysics 2007;48(2-3):103-13.
2006: Donal O'Gorman; Håkan Karlsson; S McQuaid; O Yousif; Y Rahman; Declan Gasparro; Stephan Glund; Alexander V Chibalin; Juleen R Zierath; John J Nolan
Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes.
Diabetologia 2006;49(12):2983-92.
2006: Tomas Fritz; David Kitz Krämer; Håkan Karlsson; Dana Galuska; Peter Engfeldt; Juleen R Zierath; Anna Krook
Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients.
Diabetes/metabolism research and reviews 2006;22(6):492-8.
2006: J Wang; Jawed Shafqat; K Hall; Marie Ståhlberg; I-L Wivall-Helleryd; Karim Bouzakri; Juleen R Zierath; Kerstin Brismar; Hans Jörnvall; M S Lewitt
Specific cleavage of insulin-like growth factor-binding protein-1 by a novel protease activity.
Cellular and molecular life sciences : CMLS 2006;63(19-20):2405-14.
2006: Carles Cantó; Alexander V Chibalin; Brian R Barnes; Stephan Glund; Elisabeth Suárez; Jeffrey W Ryder; Manuel Palacín; Juleen R Zierath; Antonio Zorzano; Anna Gumà
Neuregulins mediate calcium-induced glucose transport during muscle contraction.
The Journal of biological chemistry 2006;281(31):21690-7.
2006: Yun Chau Long; Juleen R Zierath
AMP-activated protein kinase signaling in metabolic regulation.
The Journal of clinical investigation 2006;116(7):1776-83.
2006: Karim Bouzakri; Anna Zachrisson; Lubna Al-Khalili; Bei B Zhang; Heikki A Koistinen; Anna Krook; Juleen R Zierath
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle.
Cell metabolism 2006;4(1):89-96.
2006: Jonas T Treebak; Stephan Glund; Atul Deshmukh; Ditte K Klein; Yun Chau Long; Thomas E Jensen; Sebastian B Jørgensen; Benoit Viollet; Leif Andersson; Dietbert Neumann; Theo Wallimann; Erik A Richter; Alexander V Chibalin; Juleen R Zierath; Jørgen F P Wojtaszewski
AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.
Diabetes 2006;55(7):2051-8.
2006: Atul Deshmukh; Vernon G Coffey; Zhihui Zhong; Alexander V Chibalin; John A Hawley; Juleen R Zierath
Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle.
Diabetes 2006;55(6):1776-82.
2006: Håkan Karlsson; Maria Ahlsén; Juleen R Zierath; Harriet Wallberg-Henriksson; Heikki A Koistinen
Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients.
Diabetes 2006;55(5):1283-8.
2006: Elisabeth C Nilsson; Yun Chau Long; Sofia Martinsson; Stephan Glund; Pablo M Garcia-Roves; L Thomas Svensson; Leif Andersson; Juleen R Zierath; Margit Mahlapuu
Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice.
The Journal of biological chemistry 2006;281(11):7244-52.
2006: Karim Bouzakri; Håkan Karlsson; Henrik Vestergaard; Sten Madsbad; Erik Christiansen; Juleen R Zierath
IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.
Diabetes 2006;55(3):785-91.
2006: Galina Bryzgalova; H Gao; Bo Ahren; Juleen R Zierath; Dana Galuska; Tatiana L Steiler; Karin Dahlman-Wright; S Nilsson; Jan-�ke GUSTAFSSON; Suad Efendic; Akhtar Khan
Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver.
Diabetologia 2006;49(3):588-97.
2006: John A Hawley; Mark Hargreaves; Juleen R Zierath
Signalling mechanisms in skeletal muscle: role in substrate selection and muscle adaptation.
Essays in biochemistry 2006;42():1-12.
2006: Katja Kannisto; Alexander V Chibalin; Björn Glinghammar; Juleen R Zierath; Anders Hamsten; Ewa Ehrenborg
Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.
International journal of molecular medicine 2006;17(1):45-52.
2006: Vernon G Coffey; Zhihui Zhong; Anthony Shield; Benedict J Canny; Alexander V Chibalin; Juleen R Zierath; John A Hawley
Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):190-2.
2005: Brian R Barnes; Yun Chau Long; Tatiana L Steiler; Ying Leng; Dana Galuska; Jørgen F P Wojtaszewski; Leif Andersson; Juleen R Zierath
Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice.
Diabetes 2005;54(12):3484-9.
2005: Yun Chau Long; Brian R Barnes; Margit Mahlapuu; Tatiana L Steiler; Sofia Martinsson; Y Leng; H Wallberg-Henriksson; L Andersson; Juleen R Zierath
Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle.
Diabetologia 2005;48(11):2354-64.
2005: Peter Plomgaard; Karim Bouzakri; Rikke Krogh-Madsen; Bettina Mittendorfer; Juleen R Zierath; Bente Klarlund Pedersen
Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation.
Diabetes 2005;54(10):2939-45.
2005: Daniel Bach; Deborah Naon; Sara Pich; Francesc X Soriano; Nathalie Vega; Jennifer Rieusset; Martine Laville; Christelle Guillet; Yves Boirie; Harriet Wallberg-Henriksson; Melania Manco; Menotti Calvani; Marco Castagneto; Manuel Palacín; Geltrude Mingrone; Juleen R Zierath; Hubert Vidal; Antonio Zorzano
Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.
Diabetes 2005;54(9):2685-93.
2005: Jeffrey W Ryder; Yun Chau Long; Elisabeth Nilsson; Margit Mahlapuu; Juleen R Zierath
Effects of calcineurin activation on insulin-, AICAR- and contraction-induced glucose transport in skeletal muscle.
The Journal of physiology 2005;567(Pt 2):379-86.
2005: Håkan Karlsson; Juleen R Zierath; Susan Kane; Anna Krook; Gustav E Lienhard; Harriet Wallberg-Henriksson
Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects.
Diabetes 2005;54(6):1692-7.
2005: Lubna Al-Khalili; M Forsgren; Katja Kannisto; Juleen R Zierath; F Lönnqvist; Anna Krook
Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1.
Diabetologia 2005;48(6):1173-9.
2005: Karim Bouzakri; Heikki A Koistinen; Juleen R Zierath
Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes.
Current diabetes reviews 2005;1(2):167-74.
2005: Brian R Barnes; Juleen R Zierath
Role of AMP--activated protein kinase in the control of glucose homeostasis.
Current molecular medicine 2005;5(3):341-8.
2005: Brian R Barnes; Stephan Glund; Yun Chau Long; Göran Hjälm; Leif Andersson; Juleen R Zierath
5'-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):773-9.
2005: Håkan Karlsson; Kirsti Hällsten; Marie Björnholm; Hiroki Tsuchida; Alexander V Chibalin; Kirsi A Virtanen; Olli Heinonen; Fredrik Lönnqvist; Pirjo Nuutila; Juleen R Zierath
Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.
Diabetes 2005;54(5):1459-67.
2005: David Kitz Krämer; Lubna Al-Khalili; Sebastio Perrini; Josefin Skogsberg; Per Wretenberg; Katja Kannisto; Harriet Wallberg-Henriksson; Ewa Ehrenborg; Juleen R Zierath; Anna Krook
Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.
Diabetes 2005;54(4):1157-63.
2005: Juleen R Zierath
Kinases in diabetes. Part II. 11-12 November 2004, Manchester, UK.
IDrugs : the investigational drugs journal 2005;8(2):121-3.
2005: Juleen R Zierath
Kinases in diabetes. Part I. 11-12 November 2004, Manchester, UK.
IDrugs : the investigational drugs journal 2005;8(2):118-20.
2004: Juleen R Zierath; John A Hawley
Skeletal muscle fiber type: influence on contractile and metabolic properties.
PLoS biology 2004;2(10):e348.
2004: Brian R Barnes; Stefan Marklund; Tatiana L Steiler; Mark Walter; Göran Hjälm; Valerie AMARGER; Margit Mahlapuu; Ying Leng; Carina Johansson; Dana Galuska; Kerstin Lindgren; Magnus Abrink; David Stapleton; Juleen R Zierath; Leif Andersson
The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle.
The Journal of biological chemistry 2004;279(37):38441-7.
2004: Lubna Al-Khalili; Anna Krook; Juleen R Zierath; Gregory D Cartee
Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake.
American journal of physiology. Endocrinology and metabolism 2004;287(3):E553-7.
2004: Anna Krook; Harriet Wallberg-Henriksson; Juleen R Zierath
Sending the signal: molecular mechanisms regulating glucose uptake.
Medicine and science in sports and exercise 2004;36(7):1212-7.
2004: Håkan Karlsson; Per-Anders Nilsson; Johnny Nilsson; Alexander V Chibalin; Juleen R Zierath; Eva Blomstrand
Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise.
American journal of physiology. Endocrinology and metabolism 2004;287(1):E1-7.
2004: Ying Leng; Tatiana L Steiler; Juleen R Zierath
Effects of insulin, contraction, and phorbol esters on mitogen-activated protein kinase signaling in skeletal muscle from lean and ob/ob mice.
Diabetes 2004;53(6):1436-44.
2004: Lubna Al-Khalili; Alexander V Chibalin; Mei Yu; Bertil Sjödin; Carolina Nylén; Juleen R Zierath; Anna Krook
MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways.
American journal of physiology. Cell physiology 2004;286(6):C1410-6.
2004: Yun Chau Long; Ulrika widegren; Juleen R Zierath
Exercise-induced mitogen-activated protein kinase signalling in skeletal muscle.
The Proceedings of the Nutrition Society 2004;63(2):227-32.
2004: Ying Leng; Håkan Karlsson; Juleen R Zierath
Insulin signaling defects in type 2 diabetes.
Reviews in endocrine & metabolic disorders 2004;5(2):111-7.
2004: Heidi Storgaard; Christine B Jensen; Marie Björnholm; Xiao Mei Song; Sten Madsbad; Juleen R Zierath; Allan Vaag
Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2004;89(3):1301-11.
2004: Margit Mahlapuu; Carina Johansson; Kerstin Lindgren; Göran Hjälm; Brian R Barnes; Anna Krook; Juleen R Zierath; Leif Andersson; Stefan Marklund
Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2004;286(2):E194-200.
2004: John A Hawley; Juleen R Zierath
Integration of metabolic and mitogenic signal transduction in skeletal muscle.
Exercise and sport sciences reviews 2004;32(1):4-8.
2004: Heikki A Koistinen; Margareta Forsgren; Harriet Wallberg-Henriksson; Juleen R Zierath
Insulin action on expression of novel adipose genes in healthy and type 2 diabetic subjects.
Obesity research 2004;12(1):25-31.
2004: Sebastio Perrini; Jan Henriksson; Juleen R Zierath; Ulrika widegren
Exercise-induced protein kinase C isoform-specific activation in human skeletal muscle.
Diabetes 2004;53(1):21-4.
2003: Tatiana L Steiler; Dana Galuska; Ying Leng; Alexander V Chibalin; Marc Gilbert; Juleen R Zierath
Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats.
Endocrinology 2003;144(12):5259-67.
2003: Jeffrey W Ryder; Rhonda Bassel-Duby; Eric N Olson; Juleen R Zierath
Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways.
The Journal of biological chemistry 2003;278(45):44298-304.
2003: H A Koistinen; Alexander V Chibalin; Juleen R Zierath
Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients.
Diabetologia 2003;46(10):1324-8.
2003: Juleen R Zierath; Yuichi Kawano
The effect of hyperglycaemia on glucose disposal and insulin signal transduction in skeletal muscle.
Best practice & research. Clinical endocrinology & metabolism 2003;17(3):385-98.
2003: Jukka Kemppainen; Håkan Karlsson; Kira Q Stolen; Håkan Karlsson; Marie Björnholm; Olli Heinonen; Pirjo Nuutila; Anna Krook; Juhani Knuuti; Juleen R Zierath
Insulin signalling and resistance in patients with chronic heart failure.
The Journal of physiology 2003;550(Pt 1):305-15.
2003: Daniel Bach; Sara Pich; Francesc X Soriano; Nathalie Vega; Bernhard Baumgartner; Josep Oriola; Jens R Daugaard; Jorge Lloberas; Marta Camps; Juleen R Zierath; Rémi Rabasa-Lhoret; Harriet Wallberg-Henriksson; Martine Laville; Manuel Palacín; Hubert Vidal; Francisca Rivera; Martin Brand; Antonio Zorzano
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity.
The Journal of biological chemistry 2003;278(19):17190-7.
2003: Lubna Al-Khalili; Alexander V Chibalin; Katja Kannisto; B B Zhang; J Permert; Geoffrey D Holman; Ewa Ehrenborg; V D H Ding; Juleen R Zierath; Anna Krook
Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content.
Cellular and molecular life sciences : CMLS 2003;60(5):991-8.
2003: Heikki A Koistinen; Dana Galuska; Alexander V Chibalin; Jing Yang; Juleen R Zierath; Geoffrey D Holman; Harriet Wallberg-Henriksson
5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.
Diabetes 2003;52(5):1066-72.
2003: Bengt Isaksson; Lisa Strömmer; Helmut Friess; Markus W Büchler; Margery K Herrington; Feng Wang; Juleen R Zierath; Harriet Wallberg-Henriksson; Jörgen Larsson; Johan Permert
Impaired insulin action on phosphatidylinositol 3-kinase activity and glucose transport in skeletal muscle of pancreatic cancer patients.
Pancreas 2003;26(2):173-7.
2003: Mei Yu; Nigel K Stepto; Alexander V Chibalin; Lee G D Fryer; David Carling; Anna Krook; John A Hawley; Juleen R Zierath
Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise.
The Journal of physiology 2003;546(Pt 2):327-35.
2002: Marie Björnholm; A R He; Anneli Attersand; S Lake; S C H Liu; G E Lienhard; S Taylor; Peter Arner; Juleen R Zierath
Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans.
Diabetologia 2002;45(12):1697-702.
2002: Hiroki Tsuchida; Marie Björnholm; Maria Fernström; Dana Galuska; Per Johansson; Harriet Wallberg-Henriksson; Juleen R Zierath; Staffan Lake; Anna Krook
Gene expression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in skeletal muscle from type 2 diabetic subjects.
Pflügers Archiv : European journal of physiology 2002;445(1):25-31.
2002: Brian R Barnes; Jeffrey W Ryder; Tatiana L Steiler; Lee G D Fryer; David Carling; Juleen R Zierath
Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction.
Diabetes 2002;51(9):2703-8.
2002: Rolando B Ceddia; Heikki A Koistinen; Juleen R Zierath; Gary Sweeney
Analysis of paradoxical observations on the association between leptin and insulin resistance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1163-76.
2002: Juleen R Zierath
Invited review: Exercise training-induced changes in insulin signaling in skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(2):773-81.
2002: Juleen R Zierath; Harriet Wallberg-Henriksson
From receptor to effector: insulin signal transduction in skeletal muscle from type II diabetic patients.
Annals of the New York Academy of Sciences 2002;967():120-34.
2002: H A Koistinen; Juleen R Zierath
Regulation of glucose transport in human skeletal muscle.
Annals of medicine 2002;34(6):410-8.
2002: XM Song; M Fiedler; Dana Galuska; Jeffrey W Ryder; Maria Fernström; Alexander V Chibalin; Harriet Wallberg-Henriksson; Juleen R Zierath
5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice.
Diabetologia 2002;45(1):56-65.
2001: Heidi Storgaard; X M Song; Christine B Jensen; Sten Madsbad; Marie Björnholm; Allan Vaag; Juleen R Zierath
Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].
Diabetes 2001;50(12):2770-8.
2001: Y Kawano; Jeffrey W Ryder; J Rincon; Juleen R Zierath; Anna Krook; Harriet Wallberg-Henriksson
Evidence against high glucose as a mediator of ERK1/2 or p38 MAPK phosphorylation in rat skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2001;281(6):E1255-9.
2001: Mei Yu; Eva Blomstrand; Alexander V Chibalin; Anna Krook; Juleen R Zierath
Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle.
The Journal of physiology 2001;536(Pt 1):273-82.
2001: Alexander V Chibalin; M V Kovalenko; Jeffrey W Ryder; Eric Féraille; Harriet Wallberg-Henriksson; Juleen R Zierath
Insulin- and glucose-induced phosphorylation of the Na(+),K(+)-adenosine triphosphatase alpha-subunits in rat skeletal muscle.
Endocrinology 2001;142(8):3474-82.
2001: Harriet Wallberg-Henriksson; Juleen R Zierath
GLUT4: a key player regulating glucose homeostasis? Insights from transgenic and knockout mice (review).
Molecular membrane biology 2001;18(3):205-11.
2001: Ulrika widegren; Jeffrey W Ryder; Juleen R Zierath
Mitogen-activated protein kinase signal transduction in skeletal muscle: effects of exercise and muscle contraction.
Acta physiologica Scandinavica 2001;172(3):227-38.
2001: Jeffrey W Ryder; CP Portocarrero; XM Song; L Cui; M Yu; TP Combatsiaris; Dana Galuska; D E Bauman; David Mark Barbano; Maureen J Charron; Juleen R Zierath; Karen L Houseknecht
Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression.
Diabetes 2001;50(5):1149-57.
2001: Tsu-Shuen Tsao; Jing Li; K S Chang; Antine Elaine Stenbit; Dana Galuska; J E Anderson; Juleen R Zierath; R J McCarter; Maureen J Charron
Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):958-69.
2001: Jeffrey W Ryder; Alexander V Chibalin; Juleen R Zierath
Intracellular mechanisms underlying increases in glucose uptake in response to insulin or exercise in skeletal muscle.
Acta physiologica Scandinavica 2001;171(3):249-57.
2001: Mei Yu; Eva Blomstrand; Alexander V Chibalin; Harriet Wallberg-Henriksson; Juleen R Zierath; Anna Krook
Exercise-associated differences in an array of proteins involved in signal transduction and glucose transport.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;90(1):29-34.
2000: Anna Krook; Ulrika widegren; XJ Jiang; Jan Henriksson; Harriet Wallberg-Henriksson; D Alessi; Juleen R Zierath
Effects of exercise on mitogen- and stress-activated kinase signal transduction in human skeletal muscle.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(5):R1716-21.
2000: Juleen R Zierath; Anna Krook; Harriet Wallberg-Henriksson
Insulin action and insulin resistance in human skeletal muscle.
Diabetologia 2000;43(7):821-35.
2000: Jeffrey W Ryder; J Yang; Dana Galuska; J Rincón; Marie Björnholm; Anna Krook; Sten Lund; O Pedersen; Harriet Wallberg-Henriksson; Juleen R Zierath; Geoffrey D Holman
Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients.
Diabetes 2000;49(4):647-54.
2000: Anna Krook; Marie Björnholm; Dana Galuska; XJ Jiang; R Fahlman; Martin G Myers Jr; Harriet Wallberg-Henriksson; Juleen R Zierath
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients.
Diabetes 2000;49(2):284-92.
2000: Jeffrey W Ryder; R Fahlman; Harriet Wallberg-Henriksson; D R Alessi; Anna Krook; Juleen R Zierath
Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement Of the mitogen- and stress-activated protein kinase 1.
The Journal of biological chemistry 2000;275(2):1457-62.
2000: Alexander V Chibalin; M Yu; Jeffrey W Ryder; XM Song; Dana Galuska; Anna Krook; Harriet Wallberg-Henriksson; Juleen R Zierath
Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):38-43.
1999: J Rincón; Dana Galuska; Jeffrey W Ryder; Y Kawano; Harriet Wallberg-Henriksson; J W Gorrod; Juleen R Zierath
Effect of the nicotine metabolite 5'-hydroxycotinine on glucose transport and glycogen synthase activity in rat skeletal muscle.
Pflügers Archiv : European journal of physiology 1999;439(1-2):130-3.
1999: XM Song; Jeffrey W Ryder; Y Kawano; Alexander V Chibalin; Anna Krook; Juleen R Zierath
Muscle fiber type specificity in insulin signal transduction.
The American journal of physiology 1999;277(6 Pt 2):R1690-6.
1999: Jeffrey W Ryder; Y Kawano; Dana Galuska; R Fahlman; Harriet Wallberg-Henriksson; Maureen J Charron; Juleen R Zierath
Postexercise glucose uptake and glycogen synthesis in skeletal muscle from GLUT4-deficient mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(15):2246-56.
1999: Jeffrey W Ryder; Y Kawano; Alexander V Chibalin; J Rincón; Tsu-Shuen Tsao; Antine Elaine Stenbit; TP Combatsiaris; J Yang; Geoffrey D Holman; Maureen J Charron; Juleen R Zierath
In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle.
The Biochemical journal 1999;342 ( Pt 2)():321-8.
1999: Y Kawano; J Rincon; A Soler; Jeffrey W Ryder; LA Nolte; Juleen R Zierath; Harriet Wallberg-Henriksson
Changes in glucose transport and protein kinase Cbeta(2) in rat skeletal muscle induced by hyperglycaemia.
Diabetologia 1999;42(9):1071-9.
1999: Nils Hjeltnes; Maria Fernström; Juleen R Zierath; Anna Krook
Regulation of UCP2 and UCP3 by muscle disuse and physical activity in tetraplegic subjects.
Diabetologia 1999;42(7):826-30.
1999: J Rincón; Anna Krook; Dana Galuska; Harriet Wallberg-Henriksson; Juleen R Zierath
Altered skeletal muscle glucose transport and blood lipid levels in habitual cigarette smokers.
Clinical physiology (Oxford, England) 1999;19(2):135-42.
1999: XM Song; Y Kawano; Anna Krook; Jeffrey W Ryder; Suad Efendic; RA Roth; Harriet Wallberg-Henriksson; Juleen R Zierath
Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats.
Diabetes 1999;48(3):664-70.
1998: Nils Hjeltnes; Dana Galuska; Marie Björnholm; A K Aksnes; A Lannem; Juleen R Zierath; Harriet Wallberg-Henriksson
Exercise-induced overexpression of key regulatory proteins involved in glucose uptake and metabolism in tetraplegic persons: molecular mechanism for improved glucose homeostasis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(15):1701-12.
1998: Juleen R Zierath; J N Livingston; Anders Thörne; Jan Bolinder; S Reynisdottir; Fredrik Lönnqvist; Peter Arner
Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway.
Diabetologia 1998;41(11):1343-54.
1998: Ulrika widegren; XJ Jiang; Anna Krook; Alexander V Chibalin; Marie Björnholm; Michael Tally; R A Roth; Jan Henriksson; Harriet Wallberg-Henriksson; Juleen R Zierath
Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(13):1379-89.
1998: Anna Krook; J Digby; S O'Rahilly; Juleen R Zierath; Harriet Wallberg-Henriksson
Uncoupling protein 3 is reduced in skeletal muscle of NIDDM patients.
Diabetes 1998;47(9):1528-31.
1998: Juleen R Zierath; Tsu-Shuen Tsao; Antine Elaine Stenbit; Jeffrey W Ryder; Dana Galuska; Maureen J Charron
Restoration of hypoxia-stimulated glucose uptake in GLUT4-deficient muscles by muscle-specific GLUT4 transgenic complementation.
The Journal of biological chemistry 1998;273(33):20910-5.
1998: Anna Krook; RA Roth; XJ Jiang; Juleen R Zierath; Harriet Wallberg-Henriksson
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects.
Diabetes 1998;47(8):1281-6.
1998: Lisa Strömmer; Johan Permert; Urban Arnelo; C Koehler; Bengt Isaksson; Jörgen Larsson; Inger Lundkvist; Marie Björnholm; Y Kawano; Harriet Wallberg-Henriksson; Juleen R Zierath
Skeletal muscle insulin resistance after trauma: insulin signaling and glucose transport.
The American journal of physiology 1998;275(2 Pt 1):E351-8.
1998: Harriet Wallberg-Henriksson; J Rincon; Juleen R Zierath
Exercise in the management of non-insulin-dependent diabetes mellitus.
Sports medicine (Auckland, N.Z.) 1998;25(1):25-35.
1998: Juleen R Zierath; EU Frevert; Jeffrey W Ryder; Per-Olof Berggren; Barbara B Kahn
Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes.
Diabetes 1998;47(1):1-4.
1997: Anna Krook; Y Kawano; XM Song; S Efendić; RA Roth; Harriet Wallberg-Henriksson; Juleen R Zierath
Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats.
Diabetes 1997;46(12):2110-4.
1997: Sten Lund; Geoffrey D Holman; Juleen R Zierath; J Rincon; LA Nolte; AE Clark; Ole Schmitz; O Pedersen; Harriet Wallberg-Henriksson
Effect of insulin on GLUT4 cell surface content and turnover rate in human skeletal muscle as measured by the exofacial bis-mannose photolabeling technique.
Diabetes 1997;46(12):1965-9.
1997: Peter R Shepherd; BT Nave; J Rincon; R J Haigh; E Foulstone; C Proud; Juleen R Zierath; Kenneth Siddle; Harriet Wallberg-Henriksson
Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism.
Diabetologia 1997;40(10):1172-7.
1997: Sten Lund; O Pedersen; Geoffrey D Holman; AE Clark; Juleen R Zierath; Harriet Wallberg-Henriksson
GLUT4 translocation in human muscle strips.
Biochemical Society transactions 1997;25(3):466S.
1997: Maureen J Charron; Ellen B Katz; Juleen R Zierath
Metabolic and molecular consequences of modifying GLUT4 expression in skeletal muscle.
Biochemical Society transactions 1997;25(3):963-8.
1997: Tsu-Shuen Tsao; Antine Elaine Stenbit; Jing Li; Karen L Houseknecht; Juleen R Zierath; Ellen B Katz; Maureen J Charron
Muscle-specific transgenic complementation of GLUT4-deficient mice. Effects on glucose but not lipid metabolism.
The Journal of clinical investigation 1997;100(3):671-7.
1997: Peter R Shepherd; BT Navé; J Rincon; LA Nolte; Anna Bevan; Kenneth Siddle; Juleen R Zierath; Harriet Wallberg-Henriksson
Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle.
The Journal of biological chemistry 1997;272(30):19000-7.
1997: Marie Björnholm; Y Kawano; M Lehtihet; Juleen R Zierath
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation.
Diabetes 1997;46(3):524-7.
1997: Juleen R Zierath; Karen L Houseknecht; Luigi Gnudi; Barbara B Kahn
High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect.
Diabetes 1997;46(2):215-23.
1996: Juleen R Zierath; L He; A Gumà; E Odegoard Wahlström; Amira Klip; Harriet Wallberg-Henriksson
Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM.
Diabetologia 1996;39(10):1180-9.
1996: J Wahren; Bo-Lennart Johansson; Harriet Wallberg-Henriksson; B Linde; E Fernqvist-Forbes; Juleen R Zierath
C-peptide revisited--new physiological effects and therapeutic implications.
Journal of internal medicine 1996;240(3):115-24.
1996: A K Aksnes; Nils Hjeltnes; E O Wahlström; A Katz; Juleen R Zierath; Harriet Wallberg-Henriksson
Intact glucose transport in morphologically altered denervated skeletal muscle from quadriplegic patients.
The American journal of physiology 1996;271(3 Pt 1):E593-600.
1996: Karen L Houseknecht; A X Zhu; Luigi Gnudi; A Hamann; Juleen R Zierath; E Tozzo; Jeffrey S Flier; Barbara B Kahn
Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin.
The Journal of biological chemistry 1996;271(19):11347-55.
1996: J Rincon; Agneta Holmäng; E O Wahlström; P Lönnroth; P Björntorp; Juleen R Zierath; Harriet Wallberg-Henriksson
Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment.
Diabetes 1996;45(5):615-21.
1996: Juleen R Zierath; Aase Handberg; Michael Tally; Harriet Wallberg-Henriksson
C-peptide stimulates glucose transport in isolated human skeletal muscle independent of insulin receptor and tyrosine kinase activation.
Diabetologia 1996;39(3):306-13.
1995: L A Nolte; J Rincón; E O Wahlström; B W Craig; Juleen R Zierath; Harriet Wallberg-Henriksson
Hyperglycemia activates glucose transport in rat skeletal muscle via a Ca(2+)-dependent mechanism.
Diabetes 1995;44(11):1345-8.
1995: Juleen R Zierath; L A Nolte; E Wahlström; Dana Galuska; Peter R Shepherd; Barbara B Kahn; Harriet Wallberg-Henriksson
Carrier-mediated fructose uptake significantly contributes to carbohydrate metabolism in human skeletal muscle.
The Biochemical journal 1995;311 ( Pt 2)():517-21.
1995: A Gumà; Juleen R Zierath; Harriet Wallberg-Henriksson; Amira Klip
Insulin induces translocation of GLUT-4 glucose transporters in human skeletal muscle.
The American journal of physiology 1995;268(4 Pt 1):E613-22.
1995: L A Nolte; Samy M Abdel-Halim; I K Martin; A Guenifi; Juleen R Zierath; C G Ostenson; Harriet Wallberg-Henriksson
Development of decreased insulin-induced glucose transport in skeletal muscle of glucose-intolerant hybrids of diabetic GK rats.
Clinical science (London, England : 1979) 1995;88(3):301-6.
1994: Dana Galuska; L Nolte; E Wahlström; J S Smedegaard Kristensen; Harriet Wallberg-Henriksson; Juleen R Zierath
Effects of non-esterified fatty acids on insulin-stimulated glucose transport in isolated skeletal muscle from patients with type 2 (non-insulin-dependent) diabetes mellitus.
Acta diabetologica 1994;31(3):169-72.
1994: Dana Galuska; L A Nolte; Juleen R Zierath; Harriet Wallberg-Henriksson
Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM.
Diabetologia 1994;37(8):826-32.
1994: L A Nolte; Dana Galuska; I K Martin; Juleen R Zierath; Harriet Wallberg-Henriksson
Elevated free fatty acid levels inhibit glucose phosphorylation in slow-twitch rat skeletal muscle.
Acta physiologica Scandinavica 1994;151(1):51-9.
1994: Juleen R Zierath; Dana Galuska; L A Nolte; Anders Thörne; J S Kristensen; Harriet Wallberg-Henriksson
Effects of glycaemia on glucose transport in isolated skeletal muscle from patients with NIDDM: in vitro reversal of muscular insulin resistance.
Diabetologia 1994;37(3):270-7.
1994: Svante Norgren; Juleen R Zierath; Anna Wedell; Harriet Wallberg-Henriksson; Holger Luthman
Regulation of human insulin receptor RNA splicing in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1465-9.
1994: U Johansson; L S Eriksson; Dana Galuska; Juleen R Zierath; Harriet Wallberg-Henriksson
Insulin action on glucose transport in isolated skeletal muscle from patients with liver cirrhosis.
Scandinavian journal of gastroenterology 1994;29(1):71-6.
1993: Svante Norgren; Juleen R Zierath; Dana Galuska; Harriet Wallberg-Henriksson; Holger Luthman
Differences in the ratio of RNA encoding two isoforms of the insulin receptor between control and NIDDM patients. The RNA variant without Exon 11 predominates in both groups.
Diabetes 1993;42(5):675-81.
1992: Juleen R Zierath; Harriet Wallberg-Henriksson
Exercise training in obese diabetic patients. Special considerations.
Sports medicine (Auckland, N.Z.) 1992;14(3):171-89.
1992: Juleen R Zierath; P Bang; Dana Galuska; K Hall; Harriet Wallberg-Henriksson
Insulin-like growth factor II stimulates glucose transport in human skeletal muscle.
FEBS letters 1992;307(3):379-82.
1992: Juleen R Zierath; Dana Galuska; A Engström; K H Johnson; C Betsholtz; P Westermark; Harriet Wallberg-Henriksson
Human islet amyloid polypeptide at pharmacological levels inhibits insulin and phorbol ester-stimulated glucose transport in in vitro incubated human muscle strips.
Diabetologia 1992;35(1):26-31.
1991: Juleen R Zierath; Dana Galuska; Bo-Lennart Johansson; Harriet Wallberg-Henriksson
Effect of human C-peptide on glucose transport in in vitro incubated human skeletal muscle.
Diabetologia 1991;34(12):899-901.
1991: Dana Galuska; Juleen R Zierath; Anders Thörne; T Sonnenfeld; Harriet Wallberg-Henriksson
Metformin increases insulin-stimulated glucose transport in insulin-resistant human skeletal muscle.
Diabète & métabolisme 1991;17(1 Pt 2):159-63.