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Lynn Zijenah

Research Profile

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Zimbabwe

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TOP 3
Kusum J Nathoo; H A Mujuru; Simbarashe Rusakaniko; I Ticklay; Ocean Tobaiwa; Lynn S Zijenah
Clinical predictors of HIV infection in hospitalized children aged 2-18 months in Harare, Zimbabwe.
Geneviève Boily-Larouche; Eric A Cohen; Jean H Humphrey; Annie-Claude Labbé; Miroslav P Milev; Andrew J Mouland; Johanne Poudrier; brian ward; Djimon M Zannou; Lynn S Zijenah; Michel Roger
Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission.
Mqondisi Tshabalala; Lynn S Zijenah; Justen Manasa; Mary Mucheche; Simbarashe Rusakaniko; Elizabeth Johnston; Gerard Kadzirange; Seble Kassaye; David Katzenstein
Surveillance of transmitted antiretroviral drug resistance among HIV-1 infected women attending antenatal clinics in Chitungwiza, Zimbabwe.

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All Publications

2012: Kusum J Nathoo; H A Mujuru; Simbarashe Rusakaniko; I Ticklay; Ocean Tobaiwa; Lynn S Zijenah
Clinical predictors of HIV infection in hospitalized children aged 2-18 months in Harare, Zimbabwe.
African health sciences 2012;12(3):259-67.
2012: Geneviève Boily-Larouche; Eric A Cohen; Jean H Humphrey; Annie-Claude Labbé; Miroslav P Milev; Andrew J Mouland; Johanne Poudrier; brian ward; Djimon M Zannou; Lynn S Zijenah; Michel Roger
Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission.
PloS one 2012;7(7):e40706.
2011: Mqondisi Tshabalala; Lynn S Zijenah; Justen Manasa; Mary Mucheche; Simbarashe Rusakaniko; Elizabeth Johnston; Gerard Kadzirange; Seble Kassaye; David Katzenstein
Surveillance of transmitted antiretroviral drug resistance among HIV-1 infected women attending antenatal clinics in Chitungwiza, Zimbabwe.
PloS one 2011;6(6):e21241.
2010: Soren Gantt; Jacquelyn Carlsson; Laura Heath; Marta E Bull; Avinash K Shetty; Junior Mutsvangwa; Georgina Musingwini; Godfrey Woelk; Lynn S Zijenah; David A Katzenstein; James I Mullins; Lisa M Frenkel
Genetic analyses of HIV-1 env sequences demonstrate limited compartmentalization in breast milk and suggest viral replication within the breast that increases with mastitis.
Journal of virology 2010;84(20):10812-9.
2010: Elizabeth Johnston White; Bryan McColgan; Seble Kassaye; Lynn S Zijenah; David Katzenstein
Unusual five amino acid insert within subtype C HIV-1 envelope contributes to dual-tropism (X4R5).
AIDS (London, England) 2010;24(7):1063-4.
2009: Geneviève Boily-Larouche; Anne-Laure Iscache; Lynn S Zijenah; Jean H Humphrey; Andrew J Mouland; brian ward; Michel Roger
Functional genetic variants in DC-SIGNR are associated with mother-to-child transmission of HIV-1.
PloS one 2009;4(10):e7211.
2008: Soren Gantt; Jacquelyn Carlsson; Avinash K Shetty; Kristy D Seidel; Xuan Qin; Junior Mutsvangwa; Georgina Musingwini; Godfrey Woelk; Lynn S Zijenah; David A Katzenstein; Lisa M Frenkel
Cytomegalovirus and Epstein-Barr virus in breast milk are associated with HIV-1 shedding but not with mastitis.
AIDS (London, England) 2008;22(12):1453-60.
2008: Maurice R G O'Gorman; Lynn S Zijenah
CD4 T cell measurements in the management of antiretroviral therapy--A review with an emphasis on pediatric HIV-infected patients.
Cytometry. Part B, Clinical cytometry 2008;74 Suppl 1():S19-26.
2007: Soren Gantt; Avinash K Shetty; Kristy D Seidel; Kuda Matasa; Georgina Musingwini; Godfrey B Woelk; Lynn S Zijenah; David A Katzenstein; Lisa M Frenkel
Laboratory indicators of mastitis are not associated with elevated HIV-1 DNA loads or predictive of HIV-1 RNA loads in breast milk.
The Journal of infectious diseases 2007;196(4):570-6.
2007: Seble Kassaye; Esther Lee; Rami Kantor; Elizabeth Johnston; Mark Winters; Lynn S Zijenah; Patrick Mateta; David Katzenstein
Drug resistance in plasma and breast milk after single-dose nevirapine in subtype C HIV type 1: population and clonal sequence analysis.
AIDS research and human retroviruses 2007;23(8):1055-61.
2007: Jean H Humphrey; Kusum J Nathoo; John W Hargrove; Peter J Iliff; Kuda Mutasa; Lawrence H Moulton; Henry Chidawanyika; Lucie C Malaba; Lynn S Zijenah; Partson Zvandasara; Robert Ntozini; Clare D Zunguza; brian ward
HIV-1 and HIV-2 prevalence and associated risk factors among postnatal women in Harare, Zimbabwe.
Epidemiology and infection 2007;135(6):933-42.
2007: Geneviève Boily-Larouche; Lynn S Zijenah; Mike Mbizvo; brian ward; Michel Roger
DC-SIGN and DC-SIGNR genetic diversity among different ethnic populations: potential implications for pathogen recognition and disease susceptibility.
Human immunology 2007;68(6):523-30.
2006: Partson Zvandasara; John W Hargrove; Robert Ntozini; Henry Chidawanyika; Kuda Mutasa; Peter J Iliff; Lawrence H Moulton; Faith Mzengeza; Lucie C Malaba; brian ward; Kusum J Nathoo; Lynn S Zijenah; Michael T Mbizvo; Clare D Zunguza; Jean H Humphrey
Mortality and morbidity among postpartum HIV-positive and HIV-negative women in Zimbabwe: risk factors, causes, and impact of single-dose postpartum vitamin A supplementation.
Journal of acquired immune deficiency syndromes (1999) 2006;43(1):107-16.
2006: Jean H Humphrey; John W Hargrove; Lucie C Malaba; Peter J Iliff; Lawrence H Moulton; Kuda Mutasa; Partson Zvandasara; Kusum J Nathoo; Faith Mzengeza; Henry Chidawanyika; Lynn S Zijenah; brian ward
HIV incidence among post-partum women in Zimbabwe: risk factors and the effect of vitamin A supplementation.
AIDS (London, England) 2006;20(10):1437-46.
2006: Jean H Humphrey; Peter J Iliff; Edmore Marinda; Kuda Mutasa; Lawrence H Moulton; Henry Chidawanyika; brian ward; Kusum J Nathoo; Lucie C Malaba; Lynn S Zijenah; Partson Zvandasara; Robert Ntozini; Faith Mzengeza; Agnes I Mahomva; ANDREA RUFF; Michael T Mbizvo; Clare D Zunguza
Effects of a single large dose of vitamin A, given during the postpartum period to HIV-positive women and their infants, on child HIV infection, HIV-free survival, and mortality.
The Journal of infectious diseases 2006;193(6):860-71.
2006: Julie Lajoie; John W Hargrove; Lynn S Zijenah; Jean H Humphrey; brian ward; Michel Roger
Genetic variants in nonclassical major histocompatibility complex class I human leukocyte antigen (HLA)-E and HLA-G molecules are associated with susceptibility to heterosexual acquisition of HIV-1.
The Journal of infectious diseases 2006;193(2):298-301.
2006: Lynn S Zijenah; Gerard Kadzirange; Simbarashe Rusakaniko; T Kufa; N Gonah; Ocean Tobaiwa; C Gwanzura; E Matsikire; David A Katzenstein
A pilot study to assess the immunologic and virologic efficacy of generic nevirapine, zidovudine and lamivudine in the treatment of HIV-1 infected women with pre-exposure to single dose nevirapine or short course zidovudine and their spouses in Chitungwiza, Zimbabwe.
The Central African journal of medicine 2006;52(1-2):1-8.
2006: Lynn S Zijenah; Gerard Kadzirange; Simon Madzime; Margaret Borok; Chiedza Mudiwa; Ocean Tobaiwa; Mary Mucheche; Simbarashe Rusakaniko; David A Katzenstein
Affordable flow cytometry for enumeration of absolute CD4+ T-lymphocytes to identify subtype C HIV-1 infected adults requiring antiretroviral therapy (ART) and monitoring response to ART in a resource-limited setting.
Journal of translational medicine 2006;4():33.
2005: Esther J Lee; Rami Kantor; Lynn S Zijenah; Wayne Sheldon; Lynda Emel; Patrick Mateta; Elizabeth Johnston; Jennifer Wells; Avinash K Shetty; Hoosen Coovadia; Yvonne Maldonado; Samuel Adeniyi Jones; Lynne M Mofenson; Christopher H Contag; Mary Bassett; David A Katzenstein
Breast-milk shedding of drug-resistant HIV-1 subtype C in women exposed to single-dose nevirapine.
The Journal of infectious diseases 2005;192(7):1260-4.
2005: Lynn S Zijenah; Ocean Tobaiwa; Simbarashe Rusakaniko; Kusum J Nathoo; Margaret Nhembe; Petronella Matibe; David A Katzenstein
Signal-boosted qualitative ultrasensitive p24 antigen assay for diagnosis of subtype C HIV-1 infection in infants under the age of 2 years.
Journal of acquired immune deficiency syndromes (1999) 2005;39(4):391-4.
2005: Jean Nicholas Roy; Julie Lajoie; Lynn S Zijenah; Azemi Barama; Charles Poirier; brian ward; Michel Roger
CYP3A5 genetic polymorphisms in different ethnic populations.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(7):884-7.
2005: Clive Gray; Carolyn Williamson; Helba Bredell; Adrian Puren; Xiaohua Xia; Ruben Filter; Lynn S Zijenah; Huyen Cao; Lynn Morris; Eftyhia Vardas; Mark Colvin; Glenda Gray; James McIntyre; ROSEMARY MUSONDA; Susan Allen; David Katzenstein; Mike Mbizo; Newton Kumwenda; Taha E Taha; Salim Abdool Karim; Jorge Flores; Haynes W Sheppard
Viral dynamics and CD4+ T cell counts in subtype C human immunodeficiency virus type 1-infected individuals from southern Africa.
AIDS research and human retroviruses 2005;21(4):285-91.
2005: Lucie C Malaba; Peter J Iliff; Kusum J Nathoo; Edmore Marinda; Lawrence H Moulton; Lynn S Zijenah; Partson Zvandasara; brian ward; Jean H Humphrey
Effect of postpartum maternal or neonatal vitamin A supplementation on infant mortality among infants born to HIV-negative mothers in Zimbabwe.
The American journal of clinical nutrition 2005;81(2):454-60.
2004: Agatha Masemola; Tumelo Mashishi; Greg Khoury; Helba Bredell; Maria Paximadis; Tiyani Mathebula; Debra Barkhan; Adrian Puren; Eftyhia Vardas; Mark Colvin; Lynn S Zijenah; David Katzenstein; ROSEMARY MUSONDA; Susan Allen; Newton Kumwenda; Taha E Taha; Glenda Gray; James McIntyre; Salim Abdool Karim; Haynes W Sheppard; Clive Gray
Novel and promiscuous CTL epitopes in conserved regions of Gag targeted by individuals with early subtype C HIV type 1 infection from southern Africa.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4607-17.
2004: Agatha Masemola; Tumelo Mashishi; Greg Khoury; Phineas Mohube; Pauline Mokgotho; Eftyhia Vardas; Mark Colvin; Lynn S Zijenah; David Katzenstein; ROSEMARY MUSONDA; Susan Allen; Newton Kumwenda; Taha E Taha; Glenda Gray; James McIntyre; Salim Abdool Karim; Haynes W Sheppard; Clive Gray
Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load.
Journal of virology 2004;78(7):3233-43.
2004: Leslie G Louie; Wendy E Hartogensis; Rachael P Jackman; Kathleen A Schultz; Lynn S Zijenah; Carina H-Y Yiu; Viet D Nguyen; Marie Y Sohsman; David K Katzenstein; Peter R Mason
Mycobacterium tuberculosis/HIV-1 coinfection and disease: role of human leukocyte antigen variation.
The Journal of infectious diseases 2004;189(6):1084-90.
2004: Claudine Matte; Julie Lajoie; Jean-Claude Lacaille; Lynn S Zijenah; brian ward; Michel Roger
Functionally active HLA-G polymorphisms are associated with the risk of heterosexual HIV-1 infection in African women.
AIDS (London, England) 2004;18(3):427-31.
2004: Lynn S Zijenah; Lawrence H Moulton; Peter J Iliff; Kusum J Nathoo; Marshall W Munjoma; Kuda Mutasa; Lucie C Malaba; Partson Zvandasara; brian ward; Jean H Humphrey
Timing of mother-to-child transmission of HIV-1 and infant mortality in the first 6 months of life in Harare, Zimbabwe.
AIDS (London, England) 2004;18(2):273-80.
2004: Kusum J Nathoo; Simbarashe Rusakaniko; Lynn S Zijenah; J Kasule; Kassam Mahomed; A Mashu; Rg Choto; Michael T Mbizvo
Survival pattern among infants born to human immunodeficiency virus type-1 infected mothers and uninfected mothers in Harare, Zimbabwe.
The Central African journal of medicine 2004;50(1-2):1-6.
2003: Julie Lajoie; Lynn S Zijenah; Marie-Claude Faucher; brian ward; Michel Roger
Novel TAP1 polymorphisms in indigenous Zimbabweans: their potential implications on TAP function and in human diseases.
Human immunology 2003;64(8):823-9.
2003: Julie Lajoie; Lynn S Zijenah; Marie-Claude Faucher; brian ward; Michel Roger
New transporter associated with antigen processing (TAP-2) polymorphisms in the Shona people of Zimbabwe.
Human immunology 2003;64(7):733-40.
2003: Elizabeth Johnston; Lynn S Zijenah; Solomon Mutetwa; Rami Kantor; Chonticha Kittinunvorakoon; David A Katzenstein
High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment.
Journal of virology 2003;77(13):7682-8.
2002: Rami Kantor; Lynn S Zijenah; Robert W Shafer; Solomon Mutetwa; Elizabeth Johnston; R Stephen Lloyd; Andrea von Lieven; Dennis Israelski; David A Katzenstein
HIV-1 subtype C reverse transcriptase and protease genotypes in Zimbabwean patients failing antiretroviral therapy.
AIDS research and human retroviruses 2002;18(18):1407-13.
2002: Claudine Matte; Lynn S Zijenah; Jean-Claude Lacaille; brian ward; Michel Roger
Mother-to-child human leukocyte antigen G concordance: no impact on the risk of vertical transmission of HIV-1.
AIDS (London, England) 2002;16(18):2491-4.
2002: Lynn S Zijenah; Wendy E Hartogensis; David A Katzenstein; Ocean Tobaiwa; Junior Mutswangwa; Peter R Mason; Leslie G Louie
Association of high HIV-1 RNA levels and homozygosity at HLA class II DRB1 in adults coinfected with Mycobacterium tuberculosis in Harare, Zimbabwe.
Human immunology 2002;63(11):1026-32.
2002: Claudine Matte; Jean-Claude Lacaille; Lynn S Zijenah; brian ward; Michel Roger
HLA-G exhibits low level of polymorphism in indigenous East Africans.
Human immunology 2002;63(6):495-501.
2002: Hugo Guevara; Jorge Casseb; Lynn S Zijenah; Michael T Mbizvo; Leopoldo F Oceguera; Carl Hanson; David A Katzenstein; R Michael Hendry
Maternal HIV-1 antibody and vertical transmission in subtype C virus infection.
Journal of acquired immune deficiency syndromes (1999) 2002;29(5):435-40.
2001: O Chishawa; Z Ziyambi; Patricia D Ndhlovu; Simbarashe Rusakaniko; O Moyo; Lynn S Zijenah
Comparative evaluation and assessment of the diagnostic usefulness of four commercial HIV-1/HIV-2 antibody assays using two well-characterized serum panels from Blood Transfusion Service and the National Health Laboratory Services in Zimbabwe.
The Central African journal of medicine 2001;47(1):1-8.
2000: H Guevara; Elizabeth Johnston; Lynn S Zijenah; O Tobaiwa; P Mason; Christopher H Contag; Kassam Mahomed; M Hendry; David Katzenstein
Prenatal transmission of subtype C HIV-1 in Zimbabwe: HIV-1 RNA and DNA in maternal and cord blood.
Journal of acquired immune deficiency syndromes (1999) 2000;25(5):390-7.
2000: Claudine Matte; Jean-Claude Lacaille; Lynn S Zijenah; brian ward; Michel Roger
HLA-G and HLA-E polymorphisms in an indigenous African population. The ZVITAMBO Study Group.
Human immunology 2000;61(11):1150-6.
1999: Lynn S Zijenah; Jean H Humphrey; Kusum J Nathoo; Lucie C Malaba; Partson Zvandasara; Agnes I Mahomva; Peter J Iliff; Michael T Mbizvo
Evaluation of the prototype Roche DNA amplification kit incorporating the new SSK145 and SKCC1B primers in detection of human immunodeficiency virus type 1 DNA in Zimbabwe.
Journal of clinical microbiology 1999;37(11):3569-71.
1999: David A Katzenstein; Michael T Mbizvo; Lynn S Zijenah; T Gittens; Marshall W Munjoma; D Hill; Simon Madzime; Yvonne Maldonado
Serum level of maternal human immunodeficiency virus (HIV) RNA, infant mortality, and vertical transmission of HIV in Zimbabwe.
The Journal of infectious diseases 1999;179(6):1382-7.
1998: Lynn S Zijenah; Michael T Mbizvo; J Kasule; Kusum J Nathoo; Marshall W Munjoma; Kassam Mahomed; Yvonne Maldonado; Simon Madzime; David Katzenstein
Mortality in the first 2 years among infants born to human immunodeficiency virus-infected women in Harare, Zimbabwe.
The Journal of infectious diseases 1998;178(1):109-13.