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Detlef Zillikens

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Zlatko Kopecki; Ralf J Ludwig; Dedee F Murrell; Nadira Ruzehaji; Christopher Turner; Detlef Zillikens; Hioraki Iwata; Allison J Cowin
Topically applied flightless I neutralizing antibodies improve healing of blistered skin in a murine model of epidermolysis bullosa acquisita.
Tobias W Fischer; Lena H Hardkop; Konrad Kleszczyński; Nathalie Kruse; Detlef Zillikens
Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.
Stefan Tukaj; Detlef Zillikens; R J Ludwig; A Recke; Enno Schmidt; Cecylia Tukaj; M Kasperkiewicz
Vitamin D status in patients with bullous pemphigoid.

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2013: Zlatko Kopecki; Ralf J Ludwig; Dedee F Murrell; Nadira Ruzehaji; Christopher Turner; Detlef Zillikens; Hioraki Iwata; Allison J Cowin
Topically applied flightless I neutralizing antibodies improve healing of blistered skin in a murine model of epidermolysis bullosa acquisita.
The Journal of investigative dermatology 2013;133(4):1008-16.
2013: Tobias W Fischer; Lena H Hardkop; Konrad Kleszczyński; Nathalie Kruse; Detlef Zillikens
Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.
Journal of pineal research 2013;54(3):303-12.
2013: Stefan Tukaj; Detlef Zillikens; R J Ludwig; A Recke; Enno Schmidt; Cecylia Tukaj; M Kasperkiewicz
Vitamin D status in patients with bullous pemphigoid.
The British journal of dermatology 2013;168(4):873-4.
2013: Lars Komorowski; Ralf J Ludwig; Ralf Müller; Christian Probst; Andreas Recke; Richard Groves; Takashi Hashimoto; Marcel F Jonkman; Soo-Chan Kim; Winfried Stöcker; Artem Vorobyev; Detlef Zillikens; Enno Schmidt
Sensitive and specific assays for routine serological diagnosis of epidermolysis bullosa acquisita.
Journal of the American Academy of Dermatology 2013;68(3):e89-95.
2013: Unni Krishna S R L Samavedam; Jürgen Scheller; Enno Schmidt; Jürgen Westermann; Detlef Zillikens; Yask Gupta; Marcel F Jonkman; Kathrin Kalies; Stefan Rose-John; Hengameh Sadeghi; Ralf J Ludwig
Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction.
Journal of autoimmunity 2013;40():74-85.
2013: Jong Hoon Kim; S Kim; S-E Kim; Y H Kim; E B Noh; Enno Schmidt; A Vorobyev; Detlef Zillikens; Soo-Chan Kim
Serum levels of anti-type VII collagen antibodies detected by enzyme-linked immunosorbent assay in patients with epidermolysis bullosa acquisita are correlated with the severity of skin lesions.
Journal of the European Academy of Dermatology and Venereology : JEADV 2013;27(2):e224-30.
2013: Enno Schmidt; Detlef Zillikens
Pemphigoid diseases.
Lancet 2013;381(9863):320-32.
2012: Misa Hirose; Kathrin Kalies; Ralf J Ludwig; Mattias Collin; Stephanie Groth; Katerina Vafia; Jürgen Westermann; Detlef Zillikens; Enno Schmidt
Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen.
Journal of autoimmunity 2012;39(4):304-14.
2012: Iris Kamphausen; Enno Schmidt; Franziska Schulze; Detlef Zillikens; Manfred Kunz
Treatment of severe pemphigus vulgaris of the scalp with adjuvant rituximab and immunoadsorption.
European journal of dermatology : EJD 2012;22(6):786-7.
2012: S Groth; A Kuhn; A Recke; Winfried Stöcker; K Vafia; Detlef Zillikens; Cornelia Dähnrich; Enno Schmidt
Antibodies to the C-terminus of laminin γ1 are present in a distinct subgroup of patients with systemic and cutaneous lupus erythematosus.
Lupus 2012;21(13):1482-3.
2012: B Monshi; L Richter; Enno Schmidt; Detlef Zillikens; S Groth; K Rappersberger
A long-term study of a patient with anti-p200 pemphigoid: correlation of autoantibody levels with disease activity and an example of epitope spreading.
The British journal of dermatology 2012;167(5):1179-83.
2012: Irena Angelova-Fischer; V Becker; Tobias W Fischer; W Wigger-Alberti; Detlef Zillikens; S Kezic
Tandem repeated irritation in aged skin induces distinct barrier perturbation and cytokine profile in vivo.
The British journal of dermatology 2012;167(4):787-93.
2012: Michael Kasperkiewicz; Michael Meurer; Hendrik Schulze-Koops; Peter von Wussow; Detlef Zillikens; Melika Behzad; Thomas Dörner; Rüdiger Eming; Klaus Freivogel; Michael Hertl; Nicolas Hunzelmann; Enno Schmidt
Efficacy and safety of rituximab in pemphigus: experience of the German Registry of Autoimmune Diseases.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2012;10(10):727-32.
2012: Christian M Karsten; Regina Kilchenstein; Gabriele Köhl; Markus Berger; Veroniqué Blanchard; Gordon D Brown; Marc Ehlers; Julia Figge; Fred D Finkelman; Nathaniel L Harris; Constanze Hess; Ralf Ludwig; Irina V Majoul; Jacqueline U McDonald; Falk Nimmerjahn; Selinda J Orr; Manoj K Pandey; Dominique Petzold; Delyth M Reid; Marcela Rosas; Richard T Strait; Philip R Taylor; Eva Wex; André Winkler; Detlef Zillikens; Jörg Köhl
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.
Nature medicine 2012;18(9):1401-6.
2012: Michael Kasperkiewicz; Jörg Köhl; Tamás Laskay; Yask Gupta; Robert Häsler; Lars Hellberg; Misa Hirose; Hiroaki Iwata; Marcel F Jonkman; Kathrin Kalies; Steffen Möller; Falk Nimmerjahn; Ellen Rentz; Unni Samavedam; Enno Schmidt; Sabina Wende; Jürgen Westermann; Xinhua Yu; Detlef Zillikens; Ralf J Ludwig
Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury.
The Journal of pathology 2012;228(1):8-19.
2012: Damian Meyersburg; Enno Schmidt; Michael Kasperkiewicz; Detlef Zillikens
Immunoadsorption in dermatology.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2012;16(4):311-20.
2012: Ofer Sarig; Enno Schmidt; Karl Skorecki; Henri Trau; Detlef Zillikens; Lilach Zoller; Aviv Barzilai; Sharon Baum; Sivan Bercovici; Reuven Bergman; Ariel Darvasi; Dan Geiger; Ilan Goldberg; Michael Hertl; Saleh M Ibrahim; Margarita Indelman; Shirli Israeli; Oren Katz; Helena Martinez de Morentin; Dedee F Murrell; Sagi Nahum; Markus M Nöthen; Shai Rosenberg; Saharon Rosset; Nadav Sagiv; Eli Sprecher
Population-specific association between a polymorphic variant in ST18, encoding a pro-apoptotic molecule, and pemphigus vulgaris.
The Journal of investigative dermatology 2012;132(7):1798-805.
2012: Ralf J Ludwig; Andreia d C Marques; Steffen Möller; Susen Müller; Andreas Recke; Enno Schmidt; Detlef Zillikens; Saleh M Ibrahim
Identification of quantitative trait loci in experimental epidermolysis bullosa acquisita.
The Journal of investigative dermatology 2012;132(5):1409-15.
2012: I M Blöcker; Cornelia Dähnrich; Lars Komorowski; Christian Probst; S Saschenbrecker; Wolfgang Schlumberger; Winfried Stöcker; Detlef Zillikens; Enno Schmidt
Epitope mapping of BP230 leading to a novel enzyme-linked immunosorbent assay for autoantibodies in bullous pemphigoid.
The British journal of dermatology 2012;166(5):964-70.
2012: Michael Kasperkiewicz; Lars Komorowski; Christian Probst; Wolfgang Schlumberger; Winfried Stöcker; Detlef Zillikens; Cornelia Dähnrich; Christian Rose
Novel assay for detecting celiac disease-associated autoantibodies in dermatitis herpetiformis using deamidated gliadin-analogous fusion peptides.
Journal of the American Academy of Dermatology 2012;66(4):583-8.
2012: Lilia Westermann; Detlef Zillikens; Michael Weichenthal; Regine Gläser; Rainer Hügel; Markus Meier; Enno Schmidt
Glucocorticosteroid-resistant pemphigoid gestationis: successful treatment with adjuvant immunoadsorption.
The Journal of dermatology 2012;39(2):168-71.
2012: Jenny Dworschak; Miriam Freitag; Oliver J Kreuzer; Jana Langenhan; Ralf J Ludwig; Andreas Recke; Detlef Zillikens; Enno Schmidt
Mapping of B cell epitopes on desmoglein 3 in pemphigus vulgaris patients by the use of overlapping peptides.
Journal of dermatological science 2012;65(2):102-9.
2012: Michael Kasperkiewicz; Detlef Zillikens; Enno Schmidt
Pemphigoid diseases: pathogenesis, diagnosis, and treatment.
Autoimmunity 2012;45(1):55-70.
2012: Katerina Vafia; Detlef Zillikens; Tina Beckmann; Jenny Dworschak; Stephanie Groth; Takashi Hashimoto; Misa Hirose; Ralf J Ludwig; Andreas Recke; Enno Schmidt
Pathogenicity of autoantibodies in anti-p200 pemphigoid.
PloS one 2012;7(7):e41769.
2012: Nina van Beek; Detlef Zillikens; Winfried Stöcker; Inga M Bloecker; Kai Fechner; Michael Kasperkiewicz; Lars Komorowski; Christian Probst; Kristin Rentzsch; Enno Schmidt
Serological diagnosis of autoimmune bullous skin diseases: prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy.
Orphanet journal of rare diseases 2012;7():49.
2012: Michael Kasperkiewicz; Enno Schmidt; Detlef Zillikens
Current therapy of the pemphigus group.
Clinics in dermatology 2012;30(1):84-94.
2011: Christoph M Hammers; Saleh M Ibrahim; Kathrin Kalies; Ralf J Ludwig; David Banczyk; Katja Bieber; Christoph T Ellebrecht; Detlef Zillikens; Jürgen Westermann
Complement-fixing anti-type VII collagen antibodies are induced in Th1-polarized lymph nodes of epidermolysis bullosa acquisita-susceptible mice.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(10):5043-50.
2011: Zlatko Kopecki; Ralf J Ludwig; Dedee F Murrell; Xanthe L Strudwick; Detlef Zillikens; Ruth M Arkell; Leena Bruckner-Tuderman; Misa Hirose; Johannes S Kern; Allison J Cowin
Overexpression of the Flii gene increases dermal-epidermal blistering in an autoimmune ColVII mouse model of epidermolysis bullosa acquisita.
The Journal of pathology 2011;225(3):401-13.
2011: A Recke; Iakov Shimanovich; P Steven; L Westermann; Detlef Zillikens; Enno Schmidt
[Treatment-refractory anti-laminin 332 mucous membrane pemphigoid. Remission following adjuvant immunoadsorption and rituximab].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2011;62(11):852-8.
2011: Enno Schmidt; Detlef Zillikens
Diagnosis and treatment of patients with autoimmune bullous disorders in Germany.
Dermatologic clinics 2011;29(4):663-71.
2011: Michael Kasperkiewicz; Ralf J Ludwig; Christian Rose; Iakov Shimanovich; Detlef Zillikens; Enno Schmidt
Rituximab for treatment-refractory pemphigus and pemphigoid: a case series of 17 patients.
Journal of the American Academy of Dermatology 2011;65(3):552-8.
2011: Misa Hirose; Akira Ishiko; Tina Beckmann; Katja Bieber; Andreas Recke; Enno Schmidt; Atsushi Shimizu; Jürgen Westermann; Detlef Zillikens; Ralf J Ludwig
Repetitive immunization breaks tolerance to type XVII collagen and leads to bullous pemphigoid in mice.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(3):1176-83.
2011: Ralf J Ludwig; Detlef Zillikens
Pathogenesis of epidermolysis bullosa acquisita.
Dermatologic clinics 2011;29(3):493-501, xi.
2011: Michael Kasperkiewicz; Ralf J Ludwig; Moritz Magens; Rudolf Manz; Ralf Müller; Enno Schmidt; Csaba Somlai; Jürgen Westermann; Detlef Zillikens; Christoph M Hammers; Antal Orosz
Heat-shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that nonmalignant plasma cells are not therapeutic targets.
Blood 2011;117(23):6135-42.
2011: Enno Schmidt; Detlef Zillikens
The diagnosis and treatment of autoimmune blistering skin diseases.
Deutsches Ärzteblatt international 2011;108(23):399-405, I-III.
2011: Marwah Adly Saleh; Ken Ishii; Yool-Ja Kim; Akihiro Murakami; Norito Ishii; Takashi Hashimoto; Enno Schmidt; Detlef Zillikens; Yuji Shirakata; Koji Hashimoto; Yasuo Kitajima; Masayuki Amagai
Development of NC1 and NC2 domains of type VII collagen ELISA for the diagnosis and analysis of the time course of epidermolysis bullosa acquisita patients.
Journal of dermatological science 2011;62(3):169-75.
2011: Norito Ishii; Andreas Recke; Sidonia Mihai; Misa Hirose; Takashi Hashimoto; Detlef Zillikens; Ralf J Ludwig
Autoantibody-induced intestinal inflammation and weight loss in experimental epidermolysis bullosa acquisita.
The Journal of pathology 2011;224(2):234-44.
2011: Irena Angelova-Fischer; Anna-Clara Mannheimer; Anke Hinder; Andreas Ruether; Andre Franke; Reinhard H H Neubert; Tobias W Fischer; Detlef Zillikens
Distinct barrier integrity phenotypes in filaggrin-related atopic eczema following sequential tape stripping and lipid profiling.
Experimental dermatology 2011;20(4):351-6.
2011: Suhasini Kulkarni; Cassian Sitaru; Zoltan Jakus; Karen E Anderson; George Damoulakis; Keith Davidson; Misa Hirose; Jatinder Juss; David Oxley; Tamara A M Chessa; Faruk Ramadani; Herve Guillou; Anne Segonds-Pichon; Anja Fritsch; Gavin E Jarvis; Klaus Okkenhaug; Ralf Ludwig; Detlef Zillikens; Attila Mócsai; Bart Vanhaesebroeck; Len R Stephens; Phillip T Hawkins
PI3Kβ plays a critical role in neutrophil activation by immune complexes.
Science signaling 2011;4(168):ra23.
2011: David J Myers; Rashmi D Unwala; Ling Xia; Stephanie Groth; Detlef Zillikens; Erik J Stratman
Generalized annular bullous eruption--quiz case. Anti-laminin γ1 pemphigoid with a linear IgA bullous dermatosis–like presentation.
Archives of dermatology 2011;147(1):109-14.
2011: Valerie P J Saw; Enno Schmidt; Ifeoma Offiah; Grazyna Galatowicz; Detlef Zillikens; John Dart; Virginia L Calder; Julie T Daniels
Profibrotic phenotype of conjunctival fibroblasts from mucous membrane pemphigoid.
The American journal of pathology 2011;178(1):187-97.
2011: Michael Kasperkiewicz; Enno Schmidt; Yvonne Frambach; Christian Rose; Markus Meier; Martin Nitschke; Thomas M Falk; Kristian Reich; Ralf J Ludwig; Detlef Zillikens
Improvement of treatment-refractory atopic dermatitis by immunoadsorption: a pilot study.
The Journal of allergy and clinical immunology 2011;127(1):267-70, 270.e1-6.
2011: S Groth; A Recke; K Vafia; R J Ludwig; Takashi Hashimoto; Detlef Zillikens; Enno Schmidt
Development of a simple enzyme-linked immunosorbent assay for the detection of autoantibodies in anti-p200 pemphigoid.
The British journal of dermatology 2011;164(1):76-82.
2011: Ralf J Ludwig; Andreas Recke; Katja Bieber; Susen Müller; Andreia de Castro Marques; David Banczyk; Misa Hirose; Michael Kasperkiewicz; Norito Ishii; Enno Schmidt; Jürgen Westermann; Detlef Zillikens; Saleh M Ibrahim
Generation of antibodies of distinct subclasses and specificity is linked to H2s in an active mouse model of epidermolysis bullosa acquisita.
The Journal of investigative dermatology 2011;131(1):167-76.
2010: Xinhua Yu; Karoline Holdorf; Brigitte Kasper; Detlef Zillikens; Ralf J Ludwig; Frank Petersen
FcγRIIA and FcγRIIIB are required for autoantibody-induced tissue damage in experimental human models of bullous pemphigoid.
The Journal of investigative dermatology 2010;130(12):2841-4.
2010: Enno Schmidt; Detlef Zillikens
Modern diagnosis of autoimmune blistering skin diseases.
Autoimmunity reviews 2010;10(2):84-9.
2010: Irena Angelova-Fischer; Isabel M Fernandez; Marie-Hélène Donnadieu; Silvia Bulfone-Paus; Detlef Zillikens; Tobias W Fischer; Vassili Soumelis
Injury to the stratum corneum induces in vivo expression of human thymic stromal lymphopoietin in the epidermis.
The Journal of investigative dermatology 2010;130(10):2505-7.
2010: Jutta Zimmermann; Friedrich Bahmer; Christian Rose; Detlef Zillikens; Enno Schmidt
Clinical and immunopathological spectrum of paraneoplastic pemphigus.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2010;8(8):598-606.
2010: M Kasperkiewicz; U Hoppe; Detlef Zillikens; Enno Schmidt
Relapse-associated autoantibodies to BP180 in a patient with anti-p200 pemphigoid.
Clinical and experimental dermatology 2010;35(6):614-7.
2010: Adrian Baican; Corina Baican; Gabriela Chiriac; Mircea T Chiriac; Victorina Macovei; Detlef Zillikens; Dorina Ciuce; Cassian Sitaru
Pemphigus vulgaris is the most common autoimmune bullous disease in Northwestern Romania.
International journal of dermatology 2010;49(7):768-74.
2010: Andreas Recke; Cassian Sitaru; Gestur Vidarsson; Mirja Evensen; Mircea T Chiriac; Ralf J Ludwig; Detlef Zillikens
Pathogenicity of IgG subclass autoantibodies to type VII collagen: induction of dermal-epidermal separation.
Journal of autoimmunity 2010;34(4):435-44.
2010: M Kasperkiewicz; M Hirose; A Recke; Enno Schmidt; Detlef Zillikens; R J Ludwig
Clearance rates of circulating and tissue-bound autoantibodies to type VII collagen in experimental epidermolysis bullosa acquisita.
The British journal of dermatology 2010;162(5):1064-70.
2010: Enno Schmidt; Cornelia Dähnrich; Anke Rosemann; Christian Probst; Lars Komorowski; Sandra Saschenbrecker; Wolfgang Schlumberger; Winfried Stöcker; Takashi Hashimoto; Eva-Bettina Bröcker; Andreas Recke; Christian Rose; Detlef Zillikens
Novel ELISA systems for antibodies to desmoglein 1 and 3: correlation of disease activity with serum autoantibody levels in individual pemphigus patients.
Experimental dermatology 2010;19(5):458-63.
2010: I Angelova-Fischer; D Wuthe; Detlef Zillikens; B Kahle
Noninvasive bioengineering assessment of the skin barrier function in patients with chronic venous insufficiency.
The British journal of dermatology 2010;162(5):1071-5.
2010: Enno Schmidt; Detlef Zillikens
Immunoadsorption in dermatology.
Archives of dermatological research 2010;302(4):241-53.
2010: Norito Ishii; Takashi Hashimoto; Detlef Zillikens; Ralf J Ludwig
High-dose intravenous immunoglobulin (IVIG) therapy in autoimmune skin blistering diseases.
Clinical reviews in allergy & immunology 2010;38(2-3):186-95.
2010: Teruki Dainichi; Hiroshi Koga; Takako Tsuji; Norito Ishii; Bungo Ohyama; Akihiro Ueda; Yohei Natsuaki; T Karashima; Takekuni Nakama; Shinichiro Yasumoto; Detlef Zillikens; Takashi Hashimoto
From anti-p200 pemphigoid to anti-laminin gamma1 pemphigoid.
The Journal of dermatology 2010;37(3):231-8.
2010: Norito Ishii; Takahiro Hamada; Teruki Dainichi; T Karashima; Takekuni Nakama; Shinichiro Yasumoto; Detlef Zillikens; Takashi Hashimoto
Epidermolysis bullosa acquisita: what's new?
The Journal of dermatology 2010;37(3):220-30.
2010: Ana Gabriela Sitaru; Alina Sesarman; Sidonia Mihai; Mircea T Chiriac; Detlef Zillikens; Per Hultman; Werner Solbach; Cassian Sitaru
T cells are required for the production of blister-inducing autoantibodies in experimental epidermolysis bullosa acquisita.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1596-603.
2010: Michael Kasperkiewicz; Markus Meier; Detlef Zillikens; Enno Schmidt
Linear IgA disease: successful application of immunoadsorption and review of the literature.
Dermatology (Basel, Switzerland) 2010;220(3):259-63.
2010: Patrick Terheyden; Roland Houben; Parisa Pajouh; Christoph Thorns; Detlef Zillikens; Jürgen C Becker
Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene.
The Journal of investigative dermatology 2010;130(1):314-6.
2010: Katja Bieber; Shijie Sun; Norito Ishii; Michael Kasperkiewicz; Enno Schmidt; Misa Hirose; Jürgen Westermann; Xinhua Yu; Detlef Zillikens; Ralf J Ludwig
Animal models for autoimmune bullous dermatoses.
Experimental dermatology 2010;19(1):2-11.
2010: Iakov Shimanovich; Volker Merl; Detlef Zillikens; Jürgen Grabbe; Christian Rose
[Two faces of Janus. Coexistence of systemic lupus erythematosus and psoriasis in the same patient].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2010;61(1):58-63.
2009: Christian Probst; Wolfgang Schlumberger; Winfried Stöcker; Andreas Recke; Enno Schmidt; Takashi Hashimoto; Xue Jun Zhu; Detlef Zillikens; Lars Komorowski
Development of ELISA for the specific determination of autoantibodies against envoplakin and periplakin in paraneoplastic pemphigus.
Clinica chimica acta; international journal of clinical chemistry 2009;410(1-2):13-8.
2009: Thomas Dörner; David Isenberg; David Jayne; Heinz Wiendl; Detlef Zillikens; Gerd Burmester
Current status on B-cell depletion therapy in autoimmune diseases other than rheumatoid arthritis.
Autoimmunity reviews 2009;9(2):82-9.
2009: Imke Düker; Jörg Schaller; Christian Rose; Detlef Zillikens; Takashi Hashimoto; Johannes Kunze
Subcorneal pustular dermatosis-type IgA pemphigus with autoantibodies to desmocollins 1, 2, and 3.
Archives of dermatology 2009;145(10):1159-62.
2009: Enno Schmidt; Matthias Goebeler; Detlef Zillikens
Rituximab in severe pemphigus.
Annals of the New York Academy of Sciences 2009;1173():683-91.
2009: Christian Rose; Enno Schmidt; Andreas Kerstan; Sybille Thoma-Uszynski; Ulrich Wesselmann; Ulrich Käsbohrer; Detlef Zillikens; Iakov Shimanovich
Histopathology of anti-laminin 5 mucous membrane pemphigoid.
Journal of the American Academy of Dermatology 2009;61(3):433-40.
2009: Alexander Enk; Gerhard Fierlbeck; Lars French; Michael Hertl; Gerald Messer; Michael Meurer; Kerstin Steinbrink; Georg Stingl; Beatrice Volc-Platzer; Detlef Zillikens
Use of high-dose immunoglobulins in dermatology.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2009;7(9):806-812.
2009: Enno Schmidt; Kirsten Hennig; Christian Mengede; Detlef Zillikens; Arno Kromminga
Immunogenicity of rituximab in patients with severe pemphigus.
Clinical immunology (Orlando, Fla.) 2009;132(3):334-41.
2009: Andreas Recke; Christian Rose; Enno Schmidt; Eva-Bettina Bröcker; Detlef Zillikens; Cassian Sitaru
Transition from pemphigus foliaceus to bullous pemphigoid: intermolecular B-cell epitope spreading without IgG subclass shifting.
Journal of the American Academy of Dermatology 2009;61(2):333-6.
2009: Christian Rose; Franz Paul Armbruster; Jana Ruppert; Bernd-Wolfgang Igl; Detlef Zillikens; Iakov Shimanovich
Autoantibodies against epidermal transglutaminase are a sensitive diagnostic marker in patients with dermatitis herpetiformis on a normal or gluten-free diet.
Journal of the American Academy of Dermatology 2009;61(1):39-43.
2009: Franziska Bertram; Eva-B Bröcker; Detlef Zillikens; Enno Schmidt
Prospective analysis of the incidence of autoimmune bullous disorders in Lower Franconia, Germany.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2009;7(5):434-40.
2009: Enno Schmidt; Detlef Zillikens
Research in practice: diagnosis of subepidermal autoimmune bullous disorders.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2009;7(4):296-300.
2009: Silke C Hofmann; Ocko Kautz; Michael Hertl; Michael Sticherling; Detlef Zillikens; Leena Bruckner-Tuderman
Results of a survey of German dermatologists on the therapeutic approaches to pemphigus and bullous pemphigoid.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2009;7(3):227-33.
2009: Teruki Dainichi; Sadamu Kurono; Bungo Ohyama; Norito Ishii; Noriko Sanzen; Maria Hayashi; Chisei Shimono; Yukimasa Taniguchi; Hiroshi Koga; T Karashima; Shinichiro Yasumoto; Detlef Zillikens; Kiyotoshi Sekiguchi; Takashi Hashimoto
Anti-laminin gamma-1 pemphigoid.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2800-5.
2009: I Angelova-Fischer; T Pfeuti; Detlef Zillikens; Christian Rose
In vivo confocal laser scanning microscopy for non-invasive diagnosis of pemphigus foliaceus.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2009;15(1):40-4.
2009: S K Dresow; Cassian Sitaru; A Recke; Gertie J Oostingh; Detlef Zillikens; B F Gibbs
IgE autoantibodies against the intracellular domain of BP180.
The British journal of dermatology 2009;160(2):429-32.
2009: Enno Schmidt; Detlef Zillikens
Diagnosis and clinical severity markers of bullous pemphigoid.
F1000 medicine reports 2009;1():.
2008: Zhi Liu; Wen Sui; Ming-Lang Zhao; Zhuowei Li; Ning Li; Randy J Thresher; George J Giudice; Janet A Fairley; Cassian Sitaru; Detlef Zillikens; Gang Ning; M Peter Marinkovich; Luis A Diaz
Subepidermal blistering induced by human autoantibodies to BP180 requires innate immune players in a humanized bullous pemphigoid mouse model.
Journal of autoimmunity 2008;31(4):331-8.
2008: Wolfgang-Moritz Heupel; Detlef Zillikens; Detlev Drenckhahn; Jens Waschke
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):1825-34.
2008: Alina Sesarman; Ana Gabriela Sitaru; Florina Olaru; Detlef Zillikens; Cassian Sitaru
Neonatal Fc receptor deficiency protects from tissue injury in experimental epidermolysis bullosa acquisita.
Journal of molecular medicine (Berlin, Germany) 2008;86(8):951-9.
2008: Dédée F Murrell; Sarah Dick; A R Ahmed; Masayuki Amagai; Maria A Barnadas; Luca Borradori; Jean-Claude Bystryn; Giuseppe Cianchini; Luis A Diaz; David P Fivenson; Russell Hall; Karen E Harman; Takashi Hashimoto; Michael Hertl; Nico Hunzelmann; Pilar Iranzo; Pascal Joly; Marcel F Jonkman; Yasuo Kitajima; Neil J Korman; Linda K Martin; Daniel Mimouni; Amit G Pandya; Aimee S Payne; David S Rubenstein; Hiroshi Shimizu; Animesh Sinha; David Sirois; Detlef Zillikens; Victoria P Werth
Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus.
Journal of the American Academy of Dermatology 2008;58(6):1043-6.
2008: Michael Hertl; Detlef Zillikens; Luca Borradori; Leena Bruckner-Tuderman; Harald Burckhard; Rüdiger Eming; Andreas Engert; Matthias Goebeler; Silke Hofmann; Nicolas Hunzelmann; Franz Karlhofer; Ocko Kautz; Undine Lippert; Andrea Niedermeier; Martin Nitschke; Martin Pfütze; Marcel Reiser; Christian Rose; Enno Schmidt; Iakov Shimanovich; Michael Sticherling; Sonja Wolff-Franke
Recommendations for the use of rituximab (anti-CD20 antibody) in the treatment of autoimmune bullous skin diseases.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2008;6(5):366-73.
2008: Tobias Meyer-Ter-Vehn; Enno Schmidt; Detlef Zillikens; Gerd Geerling
[Mucous membrane pemphigoid with ocular involvement. Part II: therapy].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2008;105(4):405-19.
2008: Enno Schmidt; Tobias Meyer-Ter-Vehn; Detlef Zillikens; Gerd Geerling
[Mucous membrane pemphigoid with ocular involvement. Part I: Clinical manifestations, pathogenesis and diagnosis].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2008;105(3):285-97; quiz 298.
2008: A Sesarman; Sidonia Mihai; Mircea T Chiriac; F Olaru; A G Sitaru; J M Thurman; Detlef Zillikens; Cassian Sitaru
Binding of avian IgY to type VII collagen does not activate complement and leucocytes and fails to induce subepidermal blistering in mice.
The British journal of dermatology 2008;158(3):463-71.
2008: Iakov Shimanovich; Martin Nitschke; Christian Rose; Jürgen Grabbe; Detlef Zillikens
Treatment of severe pemphigus with protein A immunoadsorption, rituximab and intravenous immunoglobulins.
The British journal of dermatology 2008;158(2):382-8.
2008: Detlef Zillikens
Diagnosis of autoimmune bullous skin diseases.
Clinical laboratory 2008;54(11-12):491-503.
2008: Iakov Shimanovich; Hanieh Erdmann; Jürgen Grabbe; Detlef Zillikens; Christian Rose
Necrobiosis lipoidica in monozygotic twins.
Archives of dermatology 2008;144(1):119-20.
2007: Stefan Beissert; Thomas Werfel; Uta Frieling; Markus Böhm; Michael Sticherling; Rudolf Stadler; Detlef Zillikens; Berthold Rzany; Nicolas Hunzelmann; Michael Meurer; Harald Gollnick; Thomas Ruzicka; Hans Pillekamp; Volker Junghans; Gisela Bonsmann; Thomas A Luger
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid.
Archives of dermatology 2007;143(12):1536-42.
2007: Michael Kasperkiewicz; Detlef Zillikens
The pathophysiology of bullous pemphigoid.
Clinical reviews in allergy & immunology 2007;33(1-2):67-77.
2007: Detlef Zillikens; Kurt Derfler; Rüdiger Eming; Gerhard Fierlbeck; Matthias Goebeler; Michael Hertl; Silke C Hofmann; Franz Karlhofer; Ocko Kautz; Martin Nitschke; Andreas Opitz; Sven Quist; Christian Rose; Stefan Schanz; Enno Schmidt; Iakov Shimanovich; Michael Michael; Fabian Ziller
Recommendations for the use of immunoapheresis in the treatment of autoimmune bullous diseases.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007;5(10):881-7.
2007: Sidonia Mihai; Mircea T Chiriac; Josep E Herrero-González; Margaret Goodall; Roy Jefferis; Caroline O S Savage; Detlef Zillikens; Cassian Sitaru
IgG4 autoantibodies induce dermal-epidermal separation.
Journal of cellular and molecular medicine 2007;11(5):1117-28.
2007: Cassian Sitaru; Cornelia Dähnrich; Christian Probst; Lars Komorowski; Inga Blöcker; Enno Schmidt; Wolfgang Schlumberger; Christian Rose; Winfried Stöcker; Detlef Zillikens
Enzyme-linked immunosorbent assay using multimers of the 16th non-collagenous domain of the BP180 antigen for sensitive and specific detection of pemphigoid autoantibodies.
Experimental dermatology 2007;16(9):770-7.
2007: Volker Spindler; Detlev Drenckhahn; Detlef Zillikens; Jens Waschke
Pemphigus IgG causes skin splitting in the presence of both desmoglein 1 and desmoglein 3.
The American journal of pathology 2007;171(3):906-16.
2007: Sidonia Mihai; Mircea T Chiriac; Kazue Takahashi; Joshua M Thurman; V Michael Holers; Detlef Zillikens; Marina Botto; Cassian Sitaru
The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6514-21.
2007: Mircea T Chiriac; J Roesler; A Sindrilaru; K Scharffetter-Kochanek; Detlef Zillikens; Cassian Sitaru
NADPH oxidase is required for neutrophil-dependent autoantibody-induced tissue damage.
The Journal of pathology 2007;212(1):56-65.
2007: Iakov Shimanovich; Christian Rose; Detlef Zillikens; Jürgen Grabbe
Erythema and blistering of the left leg. Fixed drug eruption (FDE).
Archives of dermatology 2007;143(4):535-40.
2007: Christian Rose; Wolfgang Weyers; Natalja Denisjuk; Uwe Hillen; Detlef Zillikens; Iakov Shimanovich
Histopathology of anti-p200 pemphigoid.
The American Journal of dermatopathology 2007;29(2):119-24.
2007: Cassian Sitaru; Sidonia Mihai; Detlef Zillikens
The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases.
Archives of dermatological research 2007;299(1):1-8.
2007: Amrei Dilling; Christian Rose; Takashi Hashimoto; Detlef Zillikens; Iakov Shimanovich
Anti-p200 pemphigoid: a novel autoimmune subepidermal blistering disease.
The Journal of dermatology 2007;34(1):1-8.
2006: Jens Waschke; Volker Spindler; Paola Bruggeman; Detlef Zillikens; Gudula Schmidt; Detlev Drenckhahn
Inhibition of Rho A activity causes pemphigus skin blistering.
The Journal of cell biology 2006;175(5):721-7.
2006: Tamara Kopp; Cassian Sitaru; Friederike Pieczkowski; Achim Schneeberger; Dagmar Födinger; Detlef Zillikens; Georg Stingl; Franz Karlhofer
IgA pemphigus--occurrence of anti-desmocollin 1 and anti-desmoglein 1 antibody reactivity in an individual patient.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2006;4(12):1045-50.
2006: Jens Waschke; Paola Bruggeman; Werner Baumgartner; Detlef Zillikens; Detlev Drenckhahn
Wolfgang Bargmann-Preis 2006. Pemphigus foliaceus igG causes dissociation of desmoglein 1-containing junctions without blocking desmoglein 1 transinteraction.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2006;188(6):501-2.
2006: Josep E Herrero-González; José Mascaró; Carmen Herrero; Amrei Dilling; Detlef Zillikens; Cassian Sitaru
Autoantibodies from patients with BSLE inducing recruitment of leukocytes to the dermoepidermal junction and subepidermal splits in cryosections of human skin.
Archives of dermatology 2006;142(11):1513-6.
2006: Stefan Beissert; Thomas Werfel; Uta Frieling; Markus Böhm; Michael Sticherling; Rudolf Stadler; Detlef Zillikens; Berthold Rzany; Nicolas Hunzelmann; Michael Meurer; Harald Gollnick; Thomas Ruzicka; Hans Pillekamp; Volker Junghans; Thomas A Luger
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of pemphigus.
Archives of dermatology 2006;142(11):1447-54.
2006: Bernhard F Gibbs; Anne Räthling; Detlef Zillikens; Michael Huber; Helmut Haas
Initial Fc epsilon RI-mediated signal strength plays a key role in regulating basophil signaling and deactivation.
The Journal of allergy and clinical immunology 2006;118(5):1060-7.
2006: Franco Falcone; Detlef Zillikens; Bernhard F Gibbs
The 21st century renaissance of the basophil? Current insights into its role in allergic responses and innate immunity.
Experimental dermatology 2006;15(11):855-64.
2006: Enno Schmidt; Barbara Wehr; Katharina Wolf; Cassian Sitaru; Eva-B Bröcker; Detlef Zillikens
Localisation of bullous pemphigoid antigen 180 (BP180) in cultured human keratinocytes: functionally relevant modification by calcium.
Archives of dermatological research 2006;298(6):283-90.
2006: Iakov Shimanovich; Susanne Herzog; Enno Schmidt; Andreas Opitz; Erdwine Klinker; Eva-B Bröcker; Matthias Goebeler; Detlef Zillikens
Improved protocol for treatment of pemphigus vulgaris with protein A immunoadsorption.
Clinical and experimental dermatology 2006;31(6):768-74.
2006: Grace K Mulyowa; Gerold Jaeger; Jerome Kabakyenga; Eva-B Bröcker; Detlef Zillikens; Enno Schmidt
Autoimmune subepidermal blistering diseases in Uganda: correlation of autoantibody class with age of patients.
International journal of dermatology 2006;45(9):1047-52.
2006: Cassian Sitaru; Mircea T Chiriac; Sidonia Mihai; Jürgen Büning; Andreas Gebert; Akira Ishiko; Detlef Zillikens
Induction of complement-fixing autoantibodies against type VII collagen results in subepidermal blistering in mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):3461-8.
2006: Enno Schmidt; N Hunzelmann; Detlef Zillikens; Eva-B Bröcker; Matthias Goebeler
Rituximab in refractory autoimmune bullous diseases.
Clinical and experimental dermatology 2006;31(4):503-8.
2006: Florina Olaru; Sidonia Mihai; Ioan Petrescu; Detlef Zillikens; Cassian Sitaru
Generation and characterization of monoclonal antibodies against the intracellular domain of hemidesmosomal type XVII collagen.
Hybridoma (2005) 2006;25(3):158-62.
2006: Josep E Herrero-González; Olaf Brauns; Ralf Egner; Wolfgang Rönspeck; José Mascaró; Marcel F Jonkman; Detlef Zillikens; Cassian Sitaru
Immunoadsorption against two distinct epitopes on human type XVII collagen abolishes dermal-epidermal separation induced in vitro by autoantibodies from pemphigoid gestationis patients.
European journal of immunology 2006;36(4):1039-48.
2006: Enno Schmidt; Sandrine Benoit; Eva-B Bröcker; Detlef Zillikens; Matthias Goebeler
Successful adjuvant treatment of recalcitrant epidermolysis bullosa acquisita with anti-CD20 antibody rituximab.
Archives of dermatology 2006;142(2):147-50.
2006: Grace K Mulyowa; Gerold Jaeger; Cassian Sitaru; Eva-B Bröcker; Detlef Zillikens; Enno Schmidt
Scarring autoimmune bullous disease in a Ugandan patient with autoantibodies to BP180, BP230, and laminin 5.
Journal of the American Academy of Dermatology 2006;54(2 Suppl):S43-6.
2006: Sandrine Benoit; Enno Schmidt; Cassian Sitaru; Christian Rose; Matthias Goebeler; Eva-B Bröcker; Detlef Zillikens
[Anti-laminin 5 mucous membrane pemphigoid].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2006;4(1):41-4.
2005: Cassian Sitaru; Detlef Zillikens
Mechanisms of blister induction by autoantibodies.
Experimental dermatology 2005;14(12):861-75.
2005: Jens Waschke; Paola Bruggeman; Werner Baumgartner; Detlef Zillikens; Detlev Drenckhahn
Pemphigus foliaceus IgG causes dissociation of desmoglein 1-containing junctions without blocking desmoglein 1 transinteraction.
The Journal of clinical investigation 2005;115(11):3157-65.
2005: Enno Schmidt; Robert Kraensel; Matthias Goebeler; Ronald Sinkgraven; Eva-B Bröcker; Berthold Rzany; Detlef Zillikens
Treatment of bullous pemphigoid with dapsone, methylprednisolone, and topical clobetasol propionate: a retrospective study of 62 cases.
Cutis; cutaneous medicine for the practitioner 2005;76(3):205-9.
2005: Adrian Baican; Yoshiaki Hirako; Zelmira Lazarova; Kim B Yancey; Detlef Zillikens; Cassian Sitaru
IgG autoantibodies to type VII collagen and an exclusive IgG3 reactivity to the laminin alpha3 chain in a patient with an autoimmune subepidermal blistering disease.
Journal of the American Academy of Dermatology 2005;53(3):517-22.
2005: Josep E Herrero-González; Cassian Sitaru; Erdwine Klinker; Eva-B Bröcker; Detlef Zillikens
Successful adjuvant treatment of severe bullous pemphigoid by tryptophan immunoadsorption.
Clinical and experimental dermatology 2005;30(5):519-22.
2005: Franziska Mayrshofer; Michael Hertl; Ronald Sinkgraven; Michael Sticherling; Christiane Pfeiffer; Detlef Zillikens; Gerald Messer; Berthold Rzany Für Die Deutschebsd-Studiengruppe
[Significant decrease in quality of life in patients with pemphigus vulgaris. Results from the German Bullous Skin Disease (BSD) Study Group].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2005;3(6):431-5.
2005: Iakov Shimanovich; Eiko E Petersen; Wolfgang Weyers; Cassian Sitaru; Detlef Zillikens
Subepidermal blistering disease with autoantibodies to both the p200 autoantigen and the alpha3 chain of laminin 5.
Journal of the American Academy of Dermatology 2005;52(5 Suppl 1):S90-2.
2005: Alexander Kreuter; Christian Rose; Detlef Zillikens; Peter Altmeyer
Bullous rheumatoid neutrophilic dermatosis.
Journal of the American Academy of Dermatology 2005;52(5):916-8.
2005: Cassian Sitaru; Sidonia Mihai; Christoph Otto; Mircea T Chiriac; Ingrid Hausser; Barbara Dotterweich; Hitoshi Saito; Christian Rose; Akira Ishiko; Detlef Zillikens
Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen.
The Journal of clinical investigation 2005;115(4):870-8.
2005: Bernhard F Gibbs; Helmut H Wolff; Detlef Zillikens; Jürgen Grabbe
Differential role for mitogen-activated protein kinases in IgE-dependent signaling in human peripheral blood basophils: in contrast to p38 MAPK, c-Jun N-terminal kinase is poorly expressed and does not appear to control mediator release.
International archives of allergy and immunology 2005;136(4):329-39.
2005: Bernhard F Gibbs; Detlef Zillikens; Jürgen Grabbe
Nerve growth factor influences IgE-mediated human basophil activation: functional properties and intracellular mechanisms compared with IL-3.
International immunopharmacology 2005;5(4):735-47.
2005: Gertie J Oostingh; Cassian Sitaru; Detlef Zillikens; Arno Kromminga; Hardi Lührs
Subclass distribution of type VII collagen-specific autoantibodies in patients with inflammatory bowel disease.
Journal of dermatological science 2005;37(3):182-4.
2004: Zelmira Lazarova; Cassian Sitaru; Detlef Zillikens; Kim B Yancey
Comparative analysis of methods for detection of anti-laminin 5 autoantibodies in patients with anti-epiligrin cicatricial pemphigoid.
Journal of the American Academy of Dermatology 2004;51(6):886-92.
2004: Iakov Shimanovich; Sidonia Mihai; Gertie J Oostingh; T Toney Ilenchuk; Eva-B Bröcker; Ghislain Opdenakker; Detlef Zillikens; Cassian Sitaru
Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid.
The Journal of pathology 2004;204(5):519-27.
2004: Mary K Hacker-Foegen; Detlef Zillikens; George J Giudice; Mong-Shang Lin
T cell receptor gene usage of BP180-specific T lymphocytes from patients with bullous pemphigoid and pemphigoid gestationis.
Clinical immunology (Orlando, Fla.) 2004;113(2):179-86.
2004: Kathrin Sinemus; Detlef Zillikens; Percy Lehmann
[Pemphigoid gestationis--first sign of metastatic choriocarcinoma].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(10):851-4.
2004: Jennifer Hehn; Susanne Herzog; Anja Gesierich; Detlef Zillikens; Christian Rose
[Grouped blisters and mediastinal tumor in a 50-year-old woman].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(9):797-800.
2004: Matthias Goebeler; Cassian Sitaru; Detlef Zillikens
[Blistering autoimmune dermatoses (II): therapy].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(9):774-91; quiz 792-3.
2004: Iakov Shimanovich; Christian Rose; Cassian Sitaru; Eva-B Bröcker; Detlef Zillikens
Localized linear IgA disease induced by ampicillin/sulbactam.
Journal of the American Academy of Dermatology 2004;51(1):95-8.
2004: Arno Kromminga; Cassian Sitaru; Christine Hagel; Susanne Herzog; Detlef Zillikens
Development of an ELISA for the detection of autoantibodies to BP230.
Clinical immunology (Orlando, Fla.) 2004;111(1):146-52.
2004: Cassian Sitaru; Jenny Powell; Gerald Messer; Eva-B Bröcker; Fenella Wojnarowska; Detlef Zillikens
Immunoblotting and enzyme-linked immunosorbent assay for the diagnosis of pemphigoid gestationis.
Obstetrics and gynecology 2004;103(4):757-63.
2004: Ulrike Schara; Jens Tücke; Wilhelm Mortier; Thomas Nüsslein; Fatima Rouan; Ellen Pfendner; Detlef Zillikens; Leena Bruckner-Tuderman; Jouni Uitto; Gerhard Wiche; Rolf Schröder
Severe mucous membrane involvement in epidermolysis bullosa simplex with muscular dystrophy due to a novel plectin gene mutation.
European journal of pediatrics 2004;163(4-5):218-22.
2004: Enno Schmidt; B Wehr; E M Tabengwa; Stanislaus Reimer; Eva-B Bröcker; Detlef Zillikens
Elevated expression and release of tissue-type, but not urokinase-type, plasminogen activator after binding of autoantibodies to bullous pemphigoid antigen 180 in cultured human keratinocytes.
Clinical and experimental immunology 2004;135(3):497-504.
2004: Cassian Sitaru; Matthias Goebeler; Detlef Zillikens
[Bullous autoimmune dermatoses (I): Pathogenesis and diagnosis].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(2):123-8; quiz 139-40.
2004: Christian Rose; Eva-B Bröcker; Detlef Zillikens
[Relevance of histological examination in the diagnosis of autoimmune bullous dermatoses].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(2):96-104.
2004: Iakov Shimanovich; Christian Rose; Yoshiaki Hirako; Elke Butt-Dörje; Detlef Zillikens
[Anti-p200 pemphigoid--a new bullous autoimmune dermatosis].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(1):7-14.
2004: Susanne Herzog; Enno Schmidt; Matthias Goebeler; Eva-B Bröcker; Detlef Zillikens
Serum levels of autoantibodies to desmoglein 3 in patients with therapy-resistant pemphigus vulgaris successfully treated with adjuvant intravenous immunoglobulins.
Acta dermato-venereologica 2004;84(1):48-52.
2003: Yoshiaki Hirako; Yuji Nishizawa; Cassian Sitaru; Andreas Opitz; Katrin Marcus; Helmut E Meyer; Elke Butt; Katsushi Owaribe; Detlef Zillikens
The 97-kDa (LABD97) and 120-kDa (LAD-1) fragments of bullous pemphigoid antigen 180/type XVII collagen have different N-termini.
The Journal of investigative dermatology 2003;121(6):1554-6.
2003: Iakov Shimanovich; Yoshiaki Hirako; Cassian Sitaru; Takashi Hashimoto; Eva-B Bröcker; Elke Butt; Detlef Zillikens
The autoantigen of anti-p200 pemphigoid is an acidic noncollagenous N-linked glycoprotein of the cutaneous basement membrane.
The Journal of investigative dermatology 2003;121(6):1402-8.
2003: Sandrine Benoit; Christian Rose; Enno Schmidt; Detlef Zillikens
[Persistent papule/mole blisters/pustules papulary pustels on the face of a 21-year old man].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(11):907-9.
2003: Adam S Geyer; Detlef Zillikens; Christian Skrobek; Bernard A Cohen; Grant J Anhalt; H Carlos Nousari
Vesicular pemphigoid in a 16-year-old boy.
Journal of the American Academy of Dermatology 2003;49(4):722-4.
2003: Christian Rose; Detlef Zillikens
[Hemorrhages in the fingers of a 45-year-old woman].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(9):743-5.
2003: Cassian Sitaru; J Powell; Iakov Shimanovich; S Jainta; G Kirtschig; F Wojnarowska; Detlef Zillikens
Pemphigoid gestationis: maternal sera recognize epitopes restricted to the N-terminal portion of the extracellular domain of BP180 not present on its shed ectodomain.
The British journal of dermatology 2003;149(2):420-2.
2003: Enno Schmidt; Erdwine Klinker; Andreas Opitz; Susanne Herzog; Cassian Sitaru; Matthias Goebeler; B Mansouri Taleghoni; Eva-B Bröcker; Detlef Zillikens
Protein A immunoadsorption: a novel and effective adjuvant treatment of severe pemphigus.
The British journal of dermatology 2003;148(6):1222-9.
2003: Enno Schmidt; Arno Kromminga; Markus Kürschner; Heiko Zimmermann; Alisa D Katsen; Eva-B Bröcker; Detlef Zillikens; Ulrich Zimmermann; Vladimir Sukhorukov
Trehalose conserves expression of bullous pemphigoid antigen 180 during desiccation and freezing.
Journal of immunological methods 2003;275(1-2):179-90.
2003: Thomas Parlowsky; Julia Welzel; Masayuki Amagai; Detlef Zillikens; Thorsten Wygold
Neonatal pemphigus vulgaris: IgG4 autoantibodies to desmoglein 3 induce skin blisters in newborns.
Journal of the American Academy of Dermatology 2003;48(4):623-5.
2003: Alexander Enk; Michael Hertl; Gerald Messer; Michael Meurer; Ellen Rentz; Detlef Zillikens
[The use of high dose intravenous immunoglobulins in dermatology].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(3):183-90.
2003: Annette Kolb-Mäurer; H-J Koch; Cassian Sitaru; Christian Rose; Matthias Goebeler; Detlef Zillikens
[Intertriginous vesicle and pustule development in a 36-year old].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2003;54(3):294-8.
2003: Annette Kolb-Mäurer; Cassian Sitaru; Christian Rose; Eva-B Bröcker; Matthias Goebeler; Detlef Zillikens
[Treatment of lichen planus pemphigoides with acitretin and pulsed corticosteroids].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2003;54(3):268-73.
2003: Heike Leyendeckers; Kaisa Tasanen; Leena Bruckner-Tuderman; Detlef Zillikens; Cassian Sitaru; Jürgen Schmitz; Nicolas Hunzelmann
Memory B cells specific for the NC16A domain of the 180 kDa bullous pemphigoid autoantigen can be detected in peripheral blood of bullous pemphigoid patients and induced in vitro to synthesize autoantibodies.
The Journal of investigative dermatology 2003;120(3):372-8.
2003: Stefan Wöhrl; Alexandra Geusau; Franz Karlhofer; Kurt Derfler; Georg Stingl; Detlef Zillikens
Pemphigoid gestationis: treatment with immunoapheresis.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(2):126-30.
2003: Yoshiaki Hirako; Kohichiro Yoshino; Detlef Zillikens; Katsushi Owaribe
Extracellular cleavage of bullous pemphigoid antigen 180/type XVII collagen and its involvement in hemidesmosomal disassembly.
Journal of biochemistry 2003;133(2):197-206.
2003: Matthias Goebeler; Detlef Zillikens
[Blistering autoimmune diseases of childhood].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2003;54(1):14-24.
2002: Iakov Shimanovich; Christian Skrobek; Christian Rose; Zhuxiang Nie; Takashi Hashimoto; Eva-B Bröcker; Detlef Zillikens
Pemphigoid gestationis with predominant involvement of oral mucous membranes and IgA autoantibodies targeting the C-terminus of BP180.
Journal of the American Academy of Dermatology 2002;47(5):780-4.
2002: Gertie J Oostingh; Cassian Sitaru; Arno Kromminga; Dirk Dormann; Detlef Zillikens
Autoreactive T cell responses in pemphigus and pemphigoid.
Autoimmunity reviews 2002;1(5):267-72.
2002: Ruoyan Chen; Janet A Fairley; Ming-Lang Zhao; George J Giudice; Detlef Zillikens; Luis A Diaz; Zhi Liu
Macrophages, but not T and B lymphocytes, are critical for subepidermal blister formation in experimental bullous pemphigoid: macrophage-mediated neutrophil infiltration depends on mast cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3987-92.
2002: Iakov Shimanovich; Eva-B Bröcker; Detlef Zillikens
Pemphigoid gestationis: new insights into the pathogenesis lead to novel diagnostic tools.
BJOG : an international journal of obstetrics and gynaecology 2002;109(9):970-6.
2002: Enno Schmidt; B Höpfner; M Chen; C Kuhn; L Weber; Eva-B Bröcker; Leena Bruckner-Tuderman; Detlef Zillikens
Childhood epidermolysis bullosa acquisita: a novel variant with reactivity to all three structural domains of type VII collagen.
The British journal of dermatology 2002;147(3):592-7.
2002: Claudia Sommer; Thies Lindenlaub; Detlef Zillikens; Klaus V Toyka; Markus Naumann
Selective loss of cholinergic sudomotor fibers causes anhidrosis in Ross syndrome.
Annals of neurology 2002;52(2):247-50.
2002: Cassian Sitaru; Arno Kromminga; Takashi Hashimoto; Eva-B Bröcker; Detlef Zillikens
Autoantibodies to type VII collagen mediate Fcgamma-dependent neutrophil activation and induce dermal-epidermal separation in cryosections of human skin.
The American journal of pathology 2002;161(1):301-11.
2002: Enno Schmidt; Cassian Sitaru; Barbara Schubert; Ulrich Wesselmann; Arno Kromminga; Eva-B Bröcker; Detlef Zillikens
Subacute prurigo variant of bullous pemphigoid: autoantibodies show the same specificity compared with classic bullous pemphigoid.
Journal of the American Academy of Dermatology 2002;47(1):133-6.
2002: Berthold Rzany; Karin Partscht; Martin Jung; Werner Kippes; Dieter Mecking; Bozena Baima; Christin Prudlo; Beata Pawelczyk; Elisabeth M Messmer; Monika Schuhmann; Ronald Sinkgraven; Lutz Büchner; Lioba Büdinger; Christiane Pfeiffer; Michael Sticherling; Michael Hertl; Hans-Wilhelm Kaiser; Michael Meurer; Detlef Zillikens; Gerald Messer
Risk factors for lethal outcome in patients with bullous pemphigoid: low serum albumin level, high dosage of glucocorticosteroids, and old age.
Archives of dermatology 2002;138(7):903-8.
2002: Enno Schmidt; Arno Kromminga; Saskia Mimietz; Ulrich Leinfelder; Cassian Sitaru; Eva-B Bröcker; Detlef Zillikens; Ulrich Zimmermann
A highly sensitive and simple assay for the detection of circulating autoantibodies against full-length bullous pemphigoid antigen 180.
Journal of autoimmunity 2002;18(4):299-309.
2002: Rolf Schröder; Wolfram S Kunz; Fatima Rouan; Ellen Pfendner; Karen Tolksdorf; Karin Kappes-Horn; Manuela Altenschmidt-Mehring; Rupert Knoblich; Peter F.M. van der Ven; Jens Reimann; Dieter O Fürst; Ingmar Blümcke; Stefan Vielhaber; Detlef Zillikens; Sabine A Eming; Thomas Klockgether; Jouni Uitto; Gerhard Wiche; Arndt Rolfs
Disorganization of the desmin cytoskeleton and mitochondrial dysfunction in plectin-related epidermolysis bullosa simplex with muscular dystrophy.
Journal of neuropathology and experimental neurology 2002;61(6):520-30.
2002: Conleth A Egan; Carole Yee; Detlef Zillikens; Kim B Yancey
Anti-p200 pemphigoid: diagnosis and treatment of a case presenting as an inflammatory subepidermal blistering disease.
Journal of the American Academy of Dermatology 2002;46(5):786-9.
2002: Cassian Sitaru; Enno Schmidt; Steffen Petermann; Luminita S Munteanu; Eva-B Bröcker; Detlef Zillikens
Autoantibodies to bullous pemphigoid antigen 180 induce dermal-epidermal separation in cryosections of human skin.
The Journal of investigative dermatology 2002;118(4):664-71.
2002: Annette Kolb-Mäurer; Susanne Herzog; Cassian Sitaru; Christian Kneitz; Detlef Zillikens; Matthias Goebeler
[Vesicle, light hypersensitivity, mouth ulceration and arthralgia in a 40-year-old patient. Bullous systemic lupus erythematosus].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2002;53(3):202-6.
2002: Detlef Zillikens
BP180 as the common autoantigen in blistering diseases with different clinical phenotypes.
The Keio journal of medicine 2002;51(1):21-8.
2002: Lawrence S Chan; A Razzaque Ahmed; Grant J Anhalt; Wolfgang Bernauer; Kevin D Cooper; Mark J Elder; Jo-David Fine; C Stephen Foster; Reza Ghohestani; Takashi Hashimoto; Thanh Hoang-Xuan; Gudula Kirtschig; Neil J Korman; Susan Lightman; Francina Lozada-Nur; M Peter Marinkovich; Bartly J Mondino; Catherine Prost-Squarcioni; Roy S Rogers; Jane F Setterfield; Dennis P West; Fenella Wojnarowska; David T Woodley; Kim B Yancey; Detlef Zillikens; John J Zone
The first international consensus on mucous membrane pemphigoid: definition, diagnostic criteria, pathogenic factors, medical treatment, and prognostic indicators.
Archives of dermatology 2002;138(3):370-9.
2002: Mong-Shang Lin; Chang-Ling Fu; Monica Olague-Marchan; Mary K Hacker; Detlef Zillikens; George J Giudice; Janet A Fairley
Autoimmune responses in patients with linear IgA bullous dermatosis: both autoantibodies and T lymphocytes recognize the NC16A domain of the BP180 molecule.
Clinical immunology (Orlando, Fla.) 2002;102(3):310-9.
2002: K Hahn-Ristic; Berthold Rzany; Masayuki Amagai; Eva-B Bröcker; Detlef Zillikens
Increased incidence of pemphigus vulgaris in southern Europeans living in Germany compared with native Germans.
Journal of the European Academy of Dermatology and Venereology : JEADV 2002;16(1):68-71.
2002: Arno Kromminga; Cassian Sitaru; Jutta Meyer; Rüdiger Arndt; Enno Schmidt; Enno Christophers; Eva-B Bröcker; Detlef Zillikens
Cicatricial pemphigoid differs from bullous pemphigoid and pemphigoid gestationis regarding the fine specificity of autoantibodies to the BP180 NC16A domain.
Journal of dermatological science 2002;28(1):68-75.
2002: Martin Leverkus; Matthias Georgi; Zhuxiang Nie; Takashi Hashimoto; Eva-B Bröcker; Detlef Zillikens
Cicatricial pemphigoid with circulating IgA and IgG autoantibodies to the central portion of the BP180 ectodomain: beneficial effect of adjuvant therapy with high-dose intravenous immunoglobulin.
Journal of the American Academy of Dermatology 2002;46(1):116-22.
2001: Martin Leverkus; K Bhol; Yoshiaki Hirako; H Pas; Cassian Sitaru; Gerald Baier; Eva-B Bröcker; M F Jonkman; A R Ahmed; Detlef Zillikens
Cicatricial pemphigoid with circulating autoantibodies to beta4 integrin, bullous pemphigoid 180 and bullous pemphigoid 230.
The British journal of dermatology 2001;145(6):998-1004.
2001: Enno Schmidt; C Skrobek; Arno Kromminga; Takashi Hashimoto; Gerald Messer; Eva-B Bröcker; Kim B Yancey; Detlef Zillikens
Cicatricial pemphigoid: IgA and IgG autoantibodies target epitopes on both intra- and extracellular domains of bullous pemphigoid antigen 180.
The British journal of dermatology 2001;145(5):778-83.
2001: M Schachter; JC Brieva; J C Jones; Detlef Zillikens; C Skrobek; Lawrence S Chan
Pemphigoid nodularis associated with autoantibodies to the NC16A domain of BP180 and a hyperproliferative integrin profile.
Journal of the American Academy of Dermatology 2001;45(5):747-54.
2001: Enno Schmidt; Ulrich Leinfelder; Petra Gessner; Detlef Zillikens; Eva-B Bröcker; Ulrich Zimmermann
CD19+ B lymphocytes are the major source of human antibody-secreting hybridomas generated by electrofusion.
Journal of immunological methods 2001;255(1-2):93-102.
2001: S Spaeth; R Riechers; Luca Borradori; Detlef Zillikens; Lioba Büdinger; Michael Hertl
IgG, IgA and IgE autoantibodies against the ectodomain of desmoglein 3 in active pemphigus vulgaris.
The British journal of dermatology 2001;144(6):1183-8.
2001: Enno Schmidt; Stanislaus Reimer; Niels Kruse; Eva-B Bröcker; Detlef Zillikens
The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone.
Clinical and experimental immunology 2001;124(1):157-62.
2001: Matthias Georgi; C Scheckenbach; Arno Kromminga; Karin Partscht; Gerald Messer; Eva-B Bröcker; Detlef Zillikens
Mapping of epitopes on the BP180 ectodomain targeted by IgA and IgG autoantibodies in patients with the lamina lucida-type of linear IgA disease.
Archives of dermatological research 2001;293(3):109-14.
2001: Detlef Zillikens; Enno Schmidt; Stanislaus Reimer; I Chimanovitch; Katja Hardt-Weinelt; Christian Rose; Eva-B Bröcker; Martin Kock; W H Boehncke
Antibodies to desmogleins 1 and 3, but not to BP180, induce blisters in human skin grafted onto SCID mice.
The Journal of pathology 2001;193(1):117-24.
2000: Enno Schmidt; Stanislaus Reimer; Niels Kruse; S Jainta; Eva-B Bröcker; M Peter Marinkovich; George J Giudice; Detlef Zillikens
Autoantibodies to BP180 associated with bullous pemphigoid release interleukin-6 and interleukin-8 from cultured human keratinocytes.
The Journal of investigative dermatology 2000;115(5):842-8.
2000: Detlef Zillikens; A Ishiko; M F Jonkman; I Chimanovitch; H Shimizu; Takashi Hashimoto; Eva-B Bröcker
Autoantibodies in anti-p200 pemphigoid stain skin lacking laminin 5 and type VII collagen.
The British journal of dermatology 2000;143(5):1043-9.
2000: Arno Kromminga; C Scheckenbach; Matthias Georgi; Christine Hagel; Rüdiger Arndt; Enno Christophers; Eva-B Bröcker; Detlef Zillikens
Patients with bullous pemphigoid and linear IgA disease show a dual IgA and IgG autoimmune response to BP180.
Journal of autoimmunity 2000;15(3):293-300.
2000: K Hahn; Werner Kippes; Masayuki Amagai; Berthold Rzany; Eva-B Bröcker; Detlef Zillikens
[Clinical aspects and immunopathology in 48 patients with pemphigus].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(9):670-7.
2000: E Schmidt; E B Bröcker; Detlef Zillikens
[New aspects on the pathogenesis of bullous pemphigoid].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(9):637-45.
2000: Christian Rose; Detlef Zillikens
[Antibodies against tissue transglutaminase as a serological marker in dermatitis herpetiformis During].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(6):387-9.
2000: E Kersting; Matthias Goebeler; Henning Hamm; Christian Rose; Detlef Zillikens; Eva-B Bröcker
[Subepidermal bullous autoimmune dermatosis with linear deposition of IgA amd IgG].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(5):340-4.
2000: I Chimanovitch; Henning Hamm; Matthias Georgi; M Kroiss; W Stolz; C Apitz; Eva-B Bröcker; Detlef Zillikens
Bullous pemphigoid of childhood: autoantibodies target the same epitopes within the NC16A domain of BP180 as autoantibodies in bullous pemphigoid of adulthood.
Archives of dermatology 2000;136(4):527-32.
2000: R Döpp; Enno Schmidt; I Chimanovitch; Martin Leverkus; Eva-B Bröcker; Detlef Zillikens
IgG4 and IgE are the major immunoglobulins targeting the NC16A domain of BP180 in Bullous pemphigoid: serum levels of these immunoglobulins reflect disease activity.
Journal of the American Academy of Dermatology 2000;42(4):577-83.
2000: Uta Jappe; Detlef Zillikens; Bernd Bonnekoh; Harald Gollnick
Epidermolysis bullosa acquisita with ultraviolet radiationsensitivity.
The British journal of dermatology 2000;142(3):517-20.
2000: Enno Schmidt; K Obe; Eva-B Bröcker; Detlef Zillikens
Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid.
Archives of dermatology 2000;136(2):174-8.
2000: Hauke Schumann; J Baetge; Kaisa Tasanen; F Wojnarowska; Heike Schäcke; Detlef Zillikens; Leena Bruckner-Tuderman
The shed ectodomain of collagen XVII/BP180 is targeted by autoantibodies in different blistering skin diseases.
The American journal of pathology 2000;156(2):685-95.
2000: M Kunz; Fatima Rouan; Leena Pulkkinen; H Hamm; Reinhart Jeschke; Leena Bruckner-Tuderman; Eva-B Bröcker; Gerhard Wiche; Jouni Uitto; Detlef Zillikens
Mutation reports: epidermolysis bullosa simplex associated with severe mucous membrane involvement and novel mutations in the plectin gene.
The Journal of investigative dermatology 2000;114(2):376-80.
2000: José Mascaró; Detlef Zillikens; George J Giudice; Frédéric Caux; Matthew G Fleming; H M Katz; Luis A Diaz
A subepidermal bullous eruption associated with IgG autoantibodies to a 200 kd dermal antigen: the first case report from the United States.
Journal of the American Academy of Dermatology 2000;42(2 Pt 2):309-15.
2000: Enno Schmidt; Detlef Zillikens
Autoimmune and inherited subepidermal blistering diseases: advances in the clinic and the laboratory.
Advances in dermatology 2000;16():113-57; discussion 158.
2000: P Ogilvie; A Trautmann; W Dummer; Christian Rose; Eva-B Bröcker; Detlef Zillikens
[Pemphigoid gestationis without blisters].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(1):25-30.
1999: Werner Kippes; Enno Schmidt; A Roth; Berthold Rzany; Eva-B Bröcker; Detlef Zillikens
[Immunopathologic changes in 115 patients with bullous pemphigoid].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1999;50(12):866-72.
1999: Detlef Zillikens; K Herzele; Matthias Georgi; Enno Schmidt; I Chimanovitch; Hauke Schumann; José Mascaró; Luis A Diaz; Leena Bruckner-Tuderman; Eva-B Bröcker; George J Giudice
Autoantibodies in a subgroup of patients with linear IgA disease react with the NC16A domain of BP1801.
The Journal of investigative dermatology 1999;113(6):947-53.
1999: Christian Rose; Walburga Dieterich; Eva-B Bröcker; Detlef Schuppan; Detlef Zillikens
Circulating autoantibodies to tissue transglutaminase differentiate patients with dermatitis herpetiformis from those with linear IgA disease.
Journal of the American Academy of Dermatology 1999;41(6):957-61.
1999: Martin Leverkus; Enno Schmidt; Zelmira Lazarova; Eva-B Bröcker; Kim B Yancey; Detlef Zillikens
Antiepiligrin cicatricial pemphigoid: an underdiagnosed entity within the spectrum of scarring autoimmune subepidermal bullous diseases?
Archives of dermatology 1999;135(9):1091-8.
1999: M Jung; Werner Kippes; Gerald Messer; Detlef Zillikens; Berthold Rzany
Increased risk of bullous pemphigoid in male and very old patients: A population-based study on incidence.
Journal of the American Academy of Dermatology 1999;41(2 Pt 1):266-8.
1999: I Chimanovitch; Enno Schmidt; Gerald Messer; R Döpp; Karin Partscht; Eva-B Bröcker; George J Giudice; Detlef Zillikens
IgG1 and IgG3 are the major immunoglobulin subclasses targeting epitopes within the NC16A domain of BP180 in pemphigoid gestationis.
The Journal of investigative dermatology 1999;113(1):140-2.
1999: Detlef Zillikens; Frédéric Caux; José Mascaró; Ulrich Wesselmann; Enno Schmidt; Catherine Prost; J P Callen; Eva-B Bröcker; Luis A Diaz; George J Giudice
Autoantibodies in lichen planus pemphigoides react with a novel epitope within the C-terminal NC16A domain of BP180.
The Journal of investigative dermatology 1999;113(1):117-21.
1999: Detlef Zillikens
Acquired skin disease of hemidesmosomes.
Journal of dermatological science 1999;20(2):134-54.
1999: Hauke Schumann; U Amann; Kaisa Tasanen; S Müller; Detlef Zillikens; Dieter Metze; Thomas Luger; Leena Bruckner-Tuderman; Gisela Bonsmann
A child with localized vulval pemphigoid and IgG autoantibodies targeting the C-terminus of collagen XVII/BP180.
The British journal of dermatology 1999;140(6):1133-8.
1999: Enno Schmidt; K Herzele; Hauke Schumann; Ulrich Wesselmann; I Chimanovitch; Leena Bruckner-Tuderman; Eva-B Bröcker; George J Giudice; Detlef Zillikens
Linear IgA disease with circulating IgA antibodies against the NC16A domain of BP180.
The British journal of dermatology 1999;140(5):964-6.
1999: Detlef Zillikens; George J Giudice
BP180/type XVII collagen: its role in acquired and inherited disorders or the dermal-epidermal junction.
Archives of dermatological research 1999;291(4):187-94.
1999: Masayuki Amagai; Kazuyuki Tsunoda; Detlef Zillikens; Tetsuo Nagai; Takeji Nishikawa
The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile.
Journal of the American Academy of Dermatology 1999;40(2 Pt 1):167-70.
1998: H Murakami; S Nishioka; Jane F Setterfield; Balbir S Bhogal; Martin M Black; Detlef Zillikens; Kim B Yancey; Shawn D Balding; George J Giudice; Luis A Diaz; Takeji Nishikawa; C Kiyokawa; Takashi Hashimoto
Analysis of antigens targeted by circulating IgG and IgA autoantibodies in 50 patients with cicatricial pemphigoid.
Journal of dermatological science 1998;17(1):39-44.
1997: Detlef Zillikens; José Mascaró; P A Rose; Zhi Liu; S M Ewing; Frédéric Caux; Raymond G Hoffmann; Luis A Diaz; George J Giudice
A highly sensitive enzyme-linked immunosorbent assay for the detection of circulating anti-BP180 autoantibodies in patients with bullous pemphigoid.
The Journal of investigative dermatology 1997;109(5):679-83.
1997: Detlef Zillikens; P A Rose; Shawn D Balding; Zhi Liu; Monica Olague-Marchan; Luis A Diaz; George J Giudice
Tight clustering of extracellular BP180 epitopes recognized by bullous pemphigoid autoantibodies.
The Journal of investigative dermatology 1997;109(4):573-9.
1997: B Hornschuh; Henning Hamm; Sabine Wever; Takashi Hashimoto; U Schröder; Eva-B Bröcker; Detlef Zillikens
Treatment of 16 patients with bullous pemphigoid with oral tetracycline and niacinamide and topical clobetasol.
Journal of the American Academy of Dermatology 1997;36(1):101-3.
1996: S Wever; Detlef Zillikens; Eva-B Bröcker
Successful treatment of refractory mucosal lesions of pemphigus vulgaris using intravenous gammaglobulin as adjuvant therapy.
The British journal of dermatology 1996;135(5):862-3.
1996: H Murakami; Masayuki Amagai; M Higashiyama; K Hashimoto; T P Chorzelski; Balbir S Bhogal; R E Jenkins; Martin M Black; Detlef Zillikens; Takeji Nishikawa; T Hashimoto
Analysis of antigens recognized by autoantibodies in herpes gestationis. Usefulness of immunoblotting using a fusion protein representing an extracellular domain of the 180 kD bullous pemphigoid antigen.
Journal of dermatological science 1996;13(2):112-7.
1996: Enno Schmidt; Boris C Bastian; Reinhard Dummer; Hans-Peter Tony; Eva-B Bröcker; Detlef Zillikens
Detection of elevated levels of IL-4, IL-6, and IL-10 in blister fluid of bullous pemphigoid.
Archives of dermatological research 1996;288(7):353-7.
1996: Detlef Zillikens; Y Kawahara; Akira Ishiko; H Shimizu; J Mayer; C V Rank; Zhi Liu; George J Giudice; H H Tran; M Peter Marinkovich; E B Brocker; T Hashimoto
A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone.
The Journal of investigative dermatology 1996;106(6):1333-8.
1996: Detlef Zillikens; Y Kawahara; Akira Ishiko; H Shimizu; J Mayer; C V Rank; Zhi Liu; George J Giudice; H H Tran; M Peter Marinkovich; Eva-B Bröcker; T Hashimoto
A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone.
The Journal of investigative dermatology 1996;106(3):465-70.
1996: Enno Schmidt; A Ambach; Boris C Bastian; Eva-B Bröcker; Detlef Zillikens
Elevated levels of interleukin-8 in blister fluid of bullous pemphigoid compared with suction blisters of healthy control subjects.
Journal of the American Academy of Dermatology 1996;34(2 Pt 1):310-2.
1995: S Wever; C Rank; B Hornschuh; T Hashimoto; T Nishikawa; Eva-B Bröcker; Detlef Zillikens
[Bullous pemphigoid simulation subacute simple prurigo].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1995;46(11):789-95.
1995: M Axt; S Wever; Gerald Baier; S Bogdan; T Hashimoto; Eva-B Bröcker; Detlef Zillikens
[Cicatricial pemphigoid--a therapeutic problem].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1995;46(9):620-7.
1995: Detlef Zillikens; S Wever; A Roth; B Weidenthaler-Barth; T Hashimoto; Eva-B Bröcker
Incidence of autoimmune subepidermal blistering dermatoses in a region of central Germany.
Archives of dermatology 1995;131(8):957-8.
1995: S Wever; M Burger; K Langfritz; T Hashimoto; T Nishikawa; Eva-B Bröcker; Detlef Zillikens
[Herpes gestationis. Clinical spectrum and diagnostic possibilities].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1995;46(3):158-64.
1994: Detlef Zillikens; Eva-B Bröcker
[Paraneoplastic pemphigus. Induction of autoantibodies against structural proteins in the skin].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1994;45(12):827-33.
1994: Detlef Zillikens; H Erhard; C Prost; T Hashimoto; T Nishikawa; Eva-B Bröcker
[Inflammatory type of epidermolysis bullosa acquisita].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1994;45(3):166-70.
1994: A Zentner; Johann Rendl; I Grelle; Reinhard Dummer; Eva-B Bröcker; Detlef Zillikens
Elevated levels of soluble tumour necrosis factor receptor I in blister fluids of bullous pemphigoid and suction blisters.
Archives of dermatological research 1994;286(6):355-7.
1993: Detlef Zillikens; A Ambach; A Zentner; Reinhard Dummer; M Schüssler; G Burg; Eva-B Bröcker
Evidence for cell-mediated immune mechanisms in the pathology of pemphigus.
The British journal of dermatology 1993;128(6):636-43.
1993: C Blum; Detlef Zillikens; Hans-Peter Tony; A A Hartmann; G Burg
[Soluble interleukin 2 receptor as activity parameter in serum of systemic and discoid lupus erythematosus].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1993;44(5):290-5.
1993: Detlef Zillikens; A Zentner; M Burger; A A Hartmann; G Burg
[Pemphigus foliaceus caused by penicillamine].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1993;44(3):167-71.
1992: A Ambach; Detlef Zillikens; B Klingert; A A Hartmann; G Burg
[Immune phenotyping of mononuclear infiltrate in bullous pemphigoid].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1992;43(2):81-5.
1992: Detlef Zillikens; A Ambach; M Schuessler; Reinhard Dummer; A A Hartmann; G Burg
The interleukin-2 receptor in lesions and serum of bullous pemphigoid.
Archives of dermatological research 1992;284(3):141-5.
1991: R K Goldstein; Detlef Zillikens; K Miller; P Elsner; G Burg
[Local treatment of disseminated granuloma anulare with a vitamin E emulsion].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1991;42(3):176-8.
1991: Detlef Zillikens; A Bammel; C Lurz; P Elsner; G Burg
[Eosinophilia-myalgia syndrome after L-tryptophan intake].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1991;42(3):154-7.
1991: Detlef Zillikens; R K Goldstein; P Elsner; A A Hartmann; G Burg
Sweet's syndrome associated with Salmonella typhimurium infection.
Acta dermato-venereologica 1991;71(1):77-9.
1990: H Hackel; Detlef Zillikens; W Lechner; G Burg
[Unusual manifestation of scleroderma of the trunk].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1990;41(2):91-3.
1990: Detlef Zillikens; K Miller; A A Hartmann; G Burg
IgA pemphigus foliaceus: a case report.
Dermatologica 1990;181(4):304-7.