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Azel Zine

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Physiology

Disorders

Hearing Loss

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Publications

TOP 3
Ibtihel Smeti; Said Assou; Saber Masmoudi; Etienne Savary; Azel Zine
Transcriptomic analysis of the developing and adult mouse cochlear sensory epithelia.
Ibtihel Smeti; Etienne Savary; Vincent Capelle; Jean-Philippe Hugnot; Alain Uziel; Azel Zine
Expression of candidate markers for stem/progenitor cells in the inner ears of developing and adult GFAP and nestin promoter-GFP transgenic mice.
Nopporn Jongkamonwiwat; Azel Zine; Marcelo N Rivolta
Stem cell based therapy in the inner ear: appropriate donor cell types and routes for transplantation.

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All Publications

2012: Ibtihel Smeti; Said Assou; Saber Masmoudi; Etienne Savary; Azel Zine
Transcriptomic analysis of the developing and adult mouse cochlear sensory epithelia.
PloS one 2012;7(8):e42987.
2011: Ibtihel Smeti; Etienne Savary; Vincent Capelle; Jean-Philippe Hugnot; Alain Uziel; Azel Zine
Expression of candidate markers for stem/progenitor cells in the inner ears of developing and adult GFAP and nestin promoter-GFP transgenic mice.
Gene expression patterns : GEP 2011;11(1-2):22-32.
2010: Nopporn Jongkamonwiwat; Azel Zine; Marcelo N Rivolta
Stem cell based therapy in the inner ear: appropriate donor cell types and routes for transplantation.
Current drug targets 2010;11(7):888-97.
2010: Ralph N Abi-Hachem; Azel Zine; Thomas R Van De Water
The injured cochlea as a target for inflammatory processes, initiation of cell death pathways and application of related otoprotectives strategies.
Recent patents on CNS drug discovery 2010;5(2):147-63.
2009: Jean-Charles Sabourin; Karin B Ackema; David Ohayon; Pierre-Olivier Guichet; Florence E Perrin; Alain Garces; Chantal Ripoll; Jeroen Charité; Lionel Simonneau; H Kettenmann; Azel Zine; Alain Privat; Jean Valmier; Alexandre Pattyn; Jean-Philippe Hugnot
A mesenchymal-like ZEB1(+) niche harbors dorsal radial glial fibrillary acidic protein-positive stem cells in the spinal cord.
Stem cells (Dayton, Ohio) 2009;27(11):2722-33.
2009: Kei-ichi Katayama; Azel Zine; Maya Ota; Yoshifumi Matsumoto; Takashi Inoue; Bernd Fritzsch; Jun Aruga
Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice.
PloS one 2009;4(11):e7786.
2008: Etienne Savary; Jean Charles Sabourin; Julien Santo; Jean-Philippe Hugnot; Christian Chabbert; Thomas R Van De Water; Alain Uziel; Azel Zine
Cochlear stem/progenitor cells from a postnatal cochlea respond to Jagged1 and demonstrate that notch signaling promotes sphere formation and sensory potential.
Mechanisms of development 2008;125(8):674-86.
2007: Adrien A Eshraghi; Jing Wang; Eelam Adil; Jiao He; Azel Zine; Michael Bublik; Christophe Bonny; Jean-Luc Puel; Thomas J Balkany; Thomas R Van De Water
Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity.
Hearing research 2007;226(1-2):168-77.
2007: Etienne Savary; Jean-Philippe Hugnot; Yolaine Chassigneux; Cecile Travo; Christophe Duperray; Thomas R Van De Water; Azel Zine
Distinct population of hair cell progenitors can be isolated from the postnatal mouse cochlea using side population analysis.
Stem cells (Dayton, Ohio) 2007;25(2):332-9.
2006: Adrien A Eshraghi; Jiao He; Cai Hong Mou; Marek Polak; Azel Zine; Christophe Bonny; Thomas J Balkany; Thomas R Van De Water
D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2006;27(4):504-11.
2005: Christophe Bonny; Borsello Tiziana; Azel Zine
Targeting the JNK pathway as a therapeutic protective strategy for nervous system diseases.
Reviews in the neurosciences 2005;16(1):57-67.
2004: Azel Zine; Thomas R Van De Water
The MAPK/JNK signalling pathway offers potential therapeutic targets for the prevention of acquired deafness.
Current drug targets. CNS and neurological disorders 2004;3(4):325-32.
2004: Azel Zine
[Stem cells to repair neurosensory deafness?].
Médecine sciences : M/S 2004;20(5):518-20.
2003: Jing Wang; Thomas R Van De Water; Christophe Bonny; Francois de Ribaupierre; Jean-Luc Puel; Azel Zine
A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(24):8596-607.
2003: Azel Zine
Molecular mechanisms that regulate auditory hair-cell differentiation in the mammalian cochlea.
Molecular neurobiology 2003;27(2):223-38.
2002: Azel Zine; Francois de Ribaupierre
Notch/Notch ligands and Math1 expression patterns in the organ of Corti of wild-type and Hes1 and Hes5 mutant mice.
Hearing research 2002;170(1-2):22-31.
2001: Azel Zine; A Aubert; J Qiu; S Therianos; F Guillemot; R Kageyama; Francois de Ribaupierre
Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(13):4712-20.
2000: Azel Zine; Thomas R Van De Water; Francois de Ribaupierre
Notch signaling regulates the pattern of auditory hair cell differentiation in mammals.
Development (Cambridge, England) 2000;127(15):3373-83.
2000: Azel Zine; M Nyffeler; Francois de Ribaupierre
Spatial expression patterns of epidermal growth factor receptor gene transcripts in the postnatal mammalian cochlea.
Hearing research 2000;141(1-2):19-27.
1999: Azel Zine; Francois de Ribaupierre
Tissue-specific levels and cellular distribution of epidermal growth factor receptors within control and neomycin-damaged neonatal rat Organ of Corti.
Journal of neurobiology 1999;38(3):313-22.
1998: Azel Zine; Francois de Ribaupierre
Replacement of mammalian auditory hair cells.
Neuroreport 1998;9(2):263-8.